WO2003081246A8 - Treatment of congestive heart failure with natriuretic peptide and a diuretic - Google Patents

Treatment of congestive heart failure with natriuretic peptide and a diuretic

Info

Publication number
WO2003081246A8
WO2003081246A8 PCT/US2003/008211 US0308211W WO03081246A8 WO 2003081246 A8 WO2003081246 A8 WO 2003081246A8 US 0308211 W US0308211 W US 0308211W WO 03081246 A8 WO03081246 A8 WO 03081246A8
Authority
WO
WIPO (PCT)
Prior art keywords
diuretic
treatment
heart failure
congestive heart
natriuretic peptide
Prior art date
Application number
PCT/US2003/008211
Other languages
French (fr)
Other versions
WO2003081246A1 (en
Inventor
George F Schreiner
Original Assignee
Scios Inc
George F Schreiner
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scios Inc, George F Schreiner filed Critical Scios Inc
Priority to AU2003214210A priority Critical patent/AU2003214210A1/en
Priority to EP03711618A priority patent/EP1490683A2/en
Publication of WO2003081246A1 publication Critical patent/WO2003081246A1/en
Publication of WO2003081246A8 publication Critical patent/WO2003081246A8/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/58—Atrial natriuretic factor complex; Atriopeptin; Atrial natriuretic peptide [ANP]; Cardionatrin; Cardiodilatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/2242—Atrial natriuretic factor complex: Atriopeptins, atrial natriuretic protein [ANP]; Cardionatrin, Cardiodilatin

Abstract

Compositions and methods are disclosed for administration of synergistic levels of a diuretic and a natriuretic peptide, especially a recombinant form of human BNP, or hBNP. Theses compositions and methods are useful for the treatment of congestive heart failure.
PCT/US2003/008211 2002-03-18 2003-03-18 Treatment of congestive heart failure with natriuretic peptide and a diuretic WO2003081246A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU2003214210A AU2003214210A1 (en) 2002-03-18 2003-03-18 Treatment of congestive heart failure with natriuretic peptide and a diuretic
EP03711618A EP1490683A2 (en) 2002-03-18 2003-03-18 Treatment of congestive heart failure with natriuretic peptide and a diuretic

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US36463802P 2002-03-18 2002-03-18
US60/364,638 2002-03-18

Publications (2)

Publication Number Publication Date
WO2003081246A1 WO2003081246A1 (en) 2003-10-02
WO2003081246A8 true WO2003081246A8 (en) 2004-04-08

Family

ID=28454613

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2003/008211 WO2003081246A1 (en) 2002-03-18 2003-03-18 Treatment of congestive heart failure with natriuretic peptide and a diuretic

Country Status (4)

Country Link
US (1) US20040063630A1 (en)
EP (1) EP1490683A2 (en)
AU (1) AU2003214210A1 (en)
WO (1) WO2003081246A1 (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050113286A1 (en) * 2002-03-18 2005-05-26 Schreiner George F. Methods for treating congestive heart failure
DE60331584D1 (en) * 2002-11-26 2010-04-15 Biocon Ltd MODIFIED NATRIURETIC COMPOUNDS, CONJUGATES, AND ITS USES
AU2004270161A1 (en) 2003-08-28 2005-03-17 Nicox S.A. Nitrosated and nitrosylated cardiovascular compounds, compositions and methods of use
WO2005070446A1 (en) * 2004-01-15 2005-08-04 Scios Inc. Method for treating cardiac remodeling following myocardial injury
WO2006005140A2 (en) 2004-07-15 2006-01-19 The University Of Queensland Proteinaceous compounds and uses therefor
US20080207505A1 (en) * 2005-01-12 2008-08-28 James Kenneth D Bna Conjugates and Methods of Use
JP2008531579A (en) 2005-02-24 2008-08-14 ニトロメッド インコーポレーティッド Nitric oxide enhanced diuretic compounds, compositions and methods of use
HUE026231T2 (en) 2005-04-07 2016-06-28 Cardiorentis Ag Use of natriuretic peptide for treating heart failure
WO2007034498A1 (en) * 2005-09-26 2007-03-29 Compugen Ltd. Atrial natriuretic peptide (anp) splice variants and methods of using same
US20080312152A1 (en) * 2005-10-14 2008-12-18 Pollitt N Stephen Glycosylated Probnp
US8580746B2 (en) * 2006-03-30 2013-11-12 Palatin Technologies, Inc. Amide linkage cyclic natriuretic peptide constructs
AU2007233123A1 (en) * 2006-03-30 2007-10-11 Palatin Technologies, Inc. Linear natriuretic peptide constructs
WO2007115175A2 (en) 2006-03-30 2007-10-11 Palatin Technologies, Inc. Cyclic natriuretic peptide constructs
US9018168B2 (en) 2010-08-12 2015-04-28 Madeleine Pharmaceuticals Pty Ltd Therapeutic method for treating congestive heart failure
MX2019004401A (en) * 2016-10-20 2019-09-26 Cortene Inc Methods of treating diseases resulting from a maladapted stress response.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU6360394A (en) * 1993-03-03 1994-09-26 Mayo Foundation For Medical Education And Research Vasonatrin peptide and analogs thereof
US6407211B1 (en) * 1999-12-17 2002-06-18 Mayo Foundation For Medical Education And Research Chimeric natriuretic peptides
US6461828B1 (en) * 2001-09-04 2002-10-08 Syn X Pharma Conjunctive analysis of biological marker expression for diagnosing organ failure

Also Published As

Publication number Publication date
US20040063630A1 (en) 2004-04-01
EP1490683A2 (en) 2004-12-29
WO2003081246A1 (en) 2003-10-02
AU2003214210A1 (en) 2003-10-08

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