WO2003087806A3 - Method for optimizing the positions of standards on maldi targets for mass spectometry - Google Patents

Method for optimizing the positions of standards on maldi targets for mass spectometry Download PDF

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Publication number
WO2003087806A3
WO2003087806A3 PCT/EP2003/004005 EP0304005W WO03087806A3 WO 2003087806 A3 WO2003087806 A3 WO 2003087806A3 EP 0304005 W EP0304005 W EP 0304005W WO 03087806 A3 WO03087806 A3 WO 03087806A3
Authority
WO
WIPO (PCT)
Prior art keywords
standards
positions
optimizing
maldi
mass spectometry
Prior art date
Application number
PCT/EP2003/004005
Other languages
French (fr)
Other versions
WO2003087806A2 (en
Inventor
Jacques Colinge
Martin Kussmann
Gerald Rossellat
Original Assignee
Geneprot Inc
Jacques Colinge
Martin Kussmann
Gerald Rossellat
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Geneprot Inc, Jacques Colinge, Martin Kussmann, Gerald Rossellat filed Critical Geneprot Inc
Priority to AU2003229690A priority Critical patent/AU2003229690A1/en
Priority to EP03722499A priority patent/EP1495481A2/en
Publication of WO2003087806A2 publication Critical patent/WO2003087806A2/en
Publication of WO2003087806A3 publication Critical patent/WO2003087806A3/en

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Classifications

    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
    • H01J49/0409—Sample holders or containers
    • H01J49/0418—Sample holders or containers for laser desorption, e.g. matrix-assisted laser desorption/ionisation [MALDI] plates or surface enhanced laser desorption/ionisation [SELDI] plates
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/0009—Calibration of the apparatus

Abstract

The invention relates to the field of molecular mass measurement by time-of-flight mass spectrometers where the ionization of analyte substances is produced by matrix-assisted laser absorption (MALDI). Methods for the correction of flight time values based on the use of external standards are provided, and in particular methods for determining, given a MALDI target, the optimal positions of mass calibration standards are described.
PCT/EP2003/004005 2002-04-17 2003-04-16 Method for optimizing the positions of standards on maldi targets for mass spectometry WO2003087806A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU2003229690A AU2003229690A1 (en) 2002-04-17 2003-04-16 Method for optimizing the positions of standards on maldi targets for mass spectometry
EP03722499A EP1495481A2 (en) 2002-04-17 2003-04-16 Method for optimizing the positions of standards on maldi targets for mass spectrometry

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US37333502P 2002-04-17 2002-04-17
US60/373,335 2002-04-17

Publications (2)

Publication Number Publication Date
WO2003087806A2 WO2003087806A2 (en) 2003-10-23
WO2003087806A3 true WO2003087806A3 (en) 2004-03-18

Family

ID=29251018

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2003/004005 WO2003087806A2 (en) 2002-04-17 2003-04-16 Method for optimizing the positions of standards on maldi targets for mass spectometry

Country Status (3)

Country Link
EP (1) EP1495481A2 (en)
AU (1) AU2003229690A1 (en)
WO (1) WO2003087806A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2452239B (en) * 2007-06-01 2012-08-29 Kratos Analytical Ltd Method and apparatus useful for imaging
JP6285735B2 (en) * 2014-02-04 2018-02-28 日本電子株式会社 Mass spectrometer
EP3850334A4 (en) * 2018-09-10 2022-06-01 Fluidigm Canada Inc. Fused-reference particle based normalisation for imaging mass spectrometry

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5886345A (en) * 1996-09-03 1999-03-23 Bruker Daltonik Gmbh Accurate mass determination with maldi time-of-flight mass spectrometers using internal reference substances
US6287872B1 (en) * 1997-12-11 2001-09-11 Bruker Daltonik Gmbh Sample support plates for Maldi mass spectrometry including methods for manufacture of plates and application of sample

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5886345A (en) * 1996-09-03 1999-03-23 Bruker Daltonik Gmbh Accurate mass determination with maldi time-of-flight mass spectrometers using internal reference substances
US6287872B1 (en) * 1997-12-11 2001-09-11 Bruker Daltonik Gmbh Sample support plates for Maldi mass spectrometry including methods for manufacture of plates and application of sample

Also Published As

Publication number Publication date
AU2003229690A8 (en) 2003-10-27
WO2003087806A2 (en) 2003-10-23
EP1495481A2 (en) 2005-01-12
AU2003229690A1 (en) 2003-10-27

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