WO2003093290A8 - Nucleoside derivatives for treating hepatitis c virus infection - Google Patents
Nucleoside derivatives for treating hepatitis c virus infectionInfo
- Publication number
- WO2003093290A8 WO2003093290A8 PCT/US2003/014237 US0314237W WO03093290A8 WO 2003093290 A8 WO2003093290 A8 WO 2003093290A8 US 0314237 W US0314237 W US 0314237W WO 03093290 A8 WO03093290 A8 WO 03093290A8
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- virus infection
- treating hepatitis
- nucleoside derivatives
- nucleoside
- hepatitis
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
- A61K31/7072—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/052—Imidazole radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/22—Pteridine radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/23—Heterocyclic radicals containing two or more heterocyclic rings condensed among themselves or condensed with a common carbocyclic ring system, not provided for in groups C07H19/14 - C07H19/22
Abstract
Priority Applications (11)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2003232071A AU2003232071A1 (en) | 2002-05-06 | 2003-05-06 | Nucleoside derivatives for treating hepatitis c virus infection |
CA002484921A CA2484921A1 (en) | 2002-05-06 | 2003-05-06 | Nucleoside derivatives for treating hepatitis c virus infection |
MXPA04010983A MXPA04010983A (en) | 2002-05-06 | 2003-05-06 | Nucleoside derivatives for treating hepatitis c virus infection. |
JP2004501429A JP2005530759A (en) | 2002-05-06 | 2003-05-06 | Nucleoside derivatives for treating hepatitis C virus infection |
NZ536123A NZ536123A (en) | 2002-05-06 | 2003-05-06 | Nucleoside derivatives for treating hepatitis C virus infection |
EP03747674A EP1501850A2 (en) | 2002-05-06 | 2003-05-06 | Nucleoside derivatives for treating hepatitis c virus infection |
BR0309581-9A BR0309581A (en) | 2002-05-06 | 2003-05-06 | Nucleoside derivatives for treatment of hepatitis c virus infection |
KR10-2004-7017682A KR20050006221A (en) | 2002-05-06 | 2003-05-06 | Nucleoside derivatives for treating hepatitis c virus infection |
TW092128453A TW200423945A (en) | 2003-05-06 | 2003-10-14 | Nucleoside derivatives for treating hepatitis c virus infection |
IL16472904A IL164729A0 (en) | 2002-05-06 | 2004-10-20 | Nucleoside derivatives for treating hepatitis c virus infection |
NO20045247A NO20045247L (en) | 2002-05-06 | 2004-11-30 | Nucleoside derivatives for the treatment of hepatitis C virus infection |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US37862402P | 2002-05-06 | 2002-05-06 | |
US60/378,624 | 2002-05-06 | ||
US39287102P | 2002-06-28 | 2002-06-28 | |
US60/392,871 | 2002-06-28 |
Publications (3)
Publication Number | Publication Date |
---|---|
WO2003093290A2 WO2003093290A2 (en) | 2003-11-13 |
WO2003093290A3 WO2003093290A3 (en) | 2004-03-18 |
WO2003093290A8 true WO2003093290A8 (en) | 2005-05-19 |
Family
ID=31997164
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2003/014237 WO2003093290A2 (en) | 2002-05-06 | 2003-05-06 | Nucleoside derivatives for treating hepatitis c virus infection |
Country Status (14)
Country | Link |
---|---|
US (1) | US20040063658A1 (en) |
EP (1) | EP1501850A2 (en) |
JP (1) | JP2005530759A (en) |
KR (1) | KR20050006221A (en) |
CN (1) | CN1653077A (en) |
AU (1) | AU2003232071A1 (en) |
BR (1) | BR0309581A (en) |
CA (1) | CA2484921A1 (en) |
IL (1) | IL164729A0 (en) |
MX (1) | MXPA04010983A (en) |
NO (1) | NO20045247L (en) |
NZ (1) | NZ536123A (en) |
RU (1) | RU2004135392A (en) |
WO (1) | WO2003093290A2 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9186369B2 (en) | 2003-07-25 | 2015-11-17 | Idenix Pharmaceuticals, Llc | Purine nucleoside analogues for treating flaviviridae including hepatitis C |
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Free format text: IN PCT GAZETTE 46/2003 UNDER (84) ADD "HU" (EP) |