WO2004026367A2 - Connector for securing ultrasound catheter to transducer - Google Patents

Connector for securing ultrasound catheter to transducer Download PDF

Info

Publication number
WO2004026367A2
WO2004026367A2 PCT/US2003/029632 US0329632W WO2004026367A2 WO 2004026367 A2 WO2004026367 A2 WO 2004026367A2 US 0329632 W US0329632 W US 0329632W WO 2004026367 A2 WO2004026367 A2 WO 2004026367A2
Authority
WO
WIPO (PCT)
Prior art keywords
inner ring
extension
catheter
bore
ultrasound
Prior art date
Application number
PCT/US2003/029632
Other languages
French (fr)
Other versions
WO2004026367A3 (en
Inventor
Henry Nita
Martinos Tran
Original Assignee
Flowcardia, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Flowcardia, Inc. filed Critical Flowcardia, Inc.
Priority to AU2003275071A priority Critical patent/AU2003275071A1/en
Priority to EP03759339A priority patent/EP1538988A2/en
Publication of WO2004026367A2 publication Critical patent/WO2004026367A2/en
Publication of WO2004026367A3 publication Critical patent/WO2004026367A3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A61B17/22004Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for using mechanical vibrations, e.g. ultrasonic shock waves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/0046Surgical instruments, devices or methods, e.g. tourniquets with a releasable handle; with handle and operating part separable
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00477Coupling
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/12Diagnosis using ultrasonic, sonic or infrasonic waves in body cavities or body tracts, e.g. by using catheters

Definitions

  • the present invention pertains to medical equipment, and more particularly, to a device and method for attaching an ultrasound catheter to an ultrasound transducer which mitigates against breakage of the ultrasound transmission member, and which facilitates ultrasound energy propagation.
  • Ultrasound catheters have been utilized to ablate various types of obstructions from blood vessels of humans and animals.
  • Successful applications of ultrasound energy to smaller blood vessels, such as the coronary arteries requires the use of relatively small diameter ultrasound catheters which are sufficiently small and flexible to undergo transluminal advancement through the tortuous vasculature of the aortic arch and coronary tree.
  • the ultrasound transmission member which extends through such catheters is particularly susceptible to breakage and losses in the transmitted ultrasound energy.
  • Breakage of ultrasound transmission members often occurs near the proximal end thereof, generally at the coupling between the ultrasound catheter coupling and the ultrasound transducer. This is believed to be because energy concentrations are highest at these points. Thus, any external forces applied to the ultrasound transmission member in this region may result in stresses exceeding the elastic limit of the ultrasound transmission member.
  • External forces may be inadvertently and undesirably applied to the ultrasound transmission member by pressing upon, pushing, pulling, torquing, bending or bumping the ultrasound transmission member coupling during use of the ultrasound catheter.
  • Such forces when applied to the ultrasound catheter coupling area result in limited ultrasound energy transmission through the ultrasound transmission member. If ultrasound energy is being transmitted by the ultrasound transmission member at the instant such forces are applied thereto, stresses occur which commonly result in breakage of the ultrasound transmission member.
  • a connector assembly for connecting an ultrasound transducer to an ultrasound catheter that has an ultrasound transmission member extending longitudinally therethrough.
  • the connector assembly has an ultrasound transducer having a transducer housing, and an extension having a proximal end attached to the distal end of the transducer housing.
  • the connector assembly also includes a ring assembly having an inner ring and an outer ring that is received inside the bore of the outer ring.
  • the connector assembly also includes a catheter knob having a proximal end that is removably coupled to the extension. The inner ring is moved from a non- supporting position with the extension positioned inside the bore of the inner ring, to a supporting position with the catheter knob positioned inside the bore of the inner ring.
  • FIG. 1 is a perspective view of an ultrasound catheter attached to an ultrasound transducer according to one embodiment of the present invention, shown with the ring assembly in the supporting position.
  • FIG. 2 is an exploded perspective view illustrating the various elements of the ring assembly and the transducer housing of the system of FIG. 1.
  • FIG. 3 is a perspective view of the ring assembly and the transducer housing of FIG. 2 shown with the ring assembly in the non-supporting position.
  • FIG. 4A is a cross-sectional side view taken along lines 5-5 in FIG. 3 illustrating the ring assembly in the supporting position, and also illustrating the transducer and catheter knob.
  • FIG. 4B is a cross-sectional side view taken along lines 5-5 in FIG. 3 illustrating the ring assembly in the non-supporting position, and also illustrating the transducer and catheter knob.
  • FIG. 5 is a perspective view of the ultrasound catheter and the transducer housing shown with the ring assembly in the non-supporting position.
  • FIG. 6 is a cross-sectional side view of the ultrasound catheter of FIG. 1.
  • FIG. 1 illustrates an ultrasound catheter 10 that can be used for ablating and removing occlusive material inside the vessel of an animal or human being.
  • the ultrasound catheter 10 has a proximal end 12 and a distal end 14, and defines at least one lumen 15 (see FIG. 6) extending longitudinally therethrough.
  • An ultrasound transmission member 16 extends through the lumen 15 of the catheter 10 from the distal end 14 to the proximal end 12.
  • the ultrasound catheter 10 is operatively coupled at its proximal end 12, by way of a Y-connector 18, a catheter knob 20, and a ring assembly 22, to an ultrasound transducer housing 24.
  • An ultrasound transducer 25 is positioned inside the transducer housing 24, and is connected to a signal generator (not shown), which operates to send an electrical signal to the ultrasound transducer 25, which converts the electrical signal to ultrasound energy.
  • the ultrasound transducer 25 is coupled via a sonic connector 17 (described in greater detail below) to the ultrasound transmission member 16, so that the ultrasound energy can be passed through the sonic connector 17 and the ultrasound transmission member 16 to be delivered to the distal end 14 of the catheter 10.
  • a guidewire (not shown), which can be any conventional monorail or over-the-wire guidewire, may be utilized in conjunction with the catheter 10 in a manner that is well-known in the catheter art.
  • the frontal portion of the Y-connector 18 is connected to the proximal end 12 of the catheter 10 using techniques that are well-known in the catheter art.
  • An injection pump (not shown) or IV bag (not shown) can be connected, by way of an infusion tube (not shown), to an infusion port or sidearm 26 of the Y-connector 18.
  • the injection pump can be used to infuse coolant fluid (e.g., 0.9% NaCI solution) into and/or through the lumen 15 of the catheter 10.
  • coolant fluid e.g. 0.9% NaCI solution
  • Such flow of coolant fluid may be utilized to prevent overheating of the ultrasound transmission member 16 extending longitudinally through the lumen 15.
  • the injection pump may be utilized to infuse a radiographic contrast medium into the catheter 10 for purposes of imaging.
  • radiographic contrast media examples include iodinated radiographic contrast media which may be selectively infused into the catheter 10 via the injection pump are commercially available as Angiovist 370 from Berlex Labs, Wayne, N.J. and Hexabrix from Malinkrodt, St. Louis, MO.
  • the proximal end of the ultrasound transmission member 16 is attached to a sonic connector 17 which is configured to effect operative and removable attachment of the proximal end of the ultrasound transmission member 16 to the horn 19 of the ultrasound transducer 25.
  • the sonic connector 17 is preferably configured and constructed to permit passage of ultrasound energy through the ultrasound transmission member 16 with minimal lateral side-to-side movement of the ultrasound transmission member 16 while, at the same time, permitting unrestricted longitudinal forward/backward vibration or movement of the ultrasound transmission member 16.
  • the ultrasound transmission member 16 may be formed of any material capable of effectively transmitting the ultrasonic energy from the ultrasound transducer 25 to the distal end 14 of the catheter 10, including but not necessarily limited to metal, plastic, hard rubber, ceramic, fiber optics, crystal, polymers, and/or composites thereof.
  • all or a portion of the ultrasound transmission member 16 may be formed of one or more materials which exhibit super-elasticity. Such materials should preferably exhibit super-elasticity consistently within the range of temperatures normally encountered by the ultrasound transmission member 16 during operation of the catheter 10.
  • all or part of the ultrasound transmission member 16 may be formed of one or more metal alloys known as "shape memory alloys". Such super-elastic metal alloys are well-known in the art and will not be described in any further detail herein.
  • the proximal end of the Y-connector 18 is attached to the distal end of the catheter knob 20 by threadably engaging the proximal end of the Y-connector 18 inside a threaded distal bore 21 at the distal end of the catheter knob 20.
  • the proximal end of the catheter knob 20 is received by the ring assembly 22 and the distal end of the transducer housing 24.
  • the ring assembly 22 is positioned over the distal end of the transducer housing 24, and has a non-supporting position where the ring assembly 22 is retracted towards the transducer housing 24, and has a supporting position where the ring assembly 22 is extended to engage at least a portion of the catheter knob 20.
  • the ring assembly 22 functions as a support member that is disposed on the transducer housing 24 to support at least a portion of the catheter knob 20.
  • the ring assembly 22 has an inner ring 30 and an outer ring 32.
  • the inner ring 30 has a bore 34 and a longitidunal slit 38 that extends through the length of the inner ring 30.
  • the distal portion of the bore 34 can be tapered for receiving the catheter knob 20 in a manner which more tightly grips the catheter knob 20 as the inner ring 30 is moved from the non-supporting position to the supporting position.
  • the outer ring 32 also has a bore 36.
  • Each of the inner ring 30 and the outer ring 32 has an opening 40 and 42, respectively, that are aligned with each other and that are adapted to receive a locking pin 44.
  • the transducer housing 24 has a cylindrical wall 48 having two stepped cylindrical extensions 50 and 52 extending from the distal end of the housing 48.
  • the first extension 50 is attached to the distal end of the cylindrical wall 48, and has a greater outer diameter than the second extension 52 that is attached to the distal end of the first extension 50.
  • a throughbore 56 extends from the hollow interior 58 of the cylindrical wall 48 and through the extensions 50 and 52. The throughbore 56 can have the same diameter throughout its length.
  • the first extension 50 is adapted to be received inside the bore 34 of the inner ring 30, while the second extension 52 is adapted to couple the proximal end of the catheter knob 20.
  • the catheter knob 20 can be generally cylindrical having a hollow interior so that the proximal end 62 of the catheter knob 20 can be sleeved over the second extension 52 in a manner such that the outer surface of the catheter knob 20 can be substantially flush with the outer surface of the first extension 50, as best shown in FIGS. 4A and 4B.
  • a longitudinal close ended slot 60 is provided on the first extension 50 for receiving the pin 44.
  • the pin 44 extends through the openings 40, 42 and is then inserted in the slot 60, with the slot 60 defining the two limits of movement for the ring assembly 22, thereby defining the non-supporting position and the supporting position.
  • the ring assembly 22 functions as a support member that is disposed on the transducer housing 24 to support at least a portion of the catheter knob 20. Supporting of at least a portion of the catheter knob 20 mitigates against breakage of the ultrasound transmission member 16 by reducing mechanical stress applied to the proximal end thereof, particularly when ultrasound energy propogates through the ultrasound transmission member 16.
  • the ring assembly 22 tends to mitigate or prevent the transmission of external forces (e.g., caused by pushing, bending, pulling, torquing or bumping the catheter knob 20) from the catheter knob 20 to the proximal end of the ultrasound transmission member 16 extending therethrough.
  • the outer ring 32 is normally positioned over the inner ring 30 with the inner ring 30 seated in the bore 36 of the outer ring 32.
  • the combined inner and outer rings 30, 32 are then positioned over the first extension 50 so that the inner and outer rings 30, 32 are positioned against the transducer housing 24 in the non-supporting position (see FIGS. 4A and 5).
  • the proximal end 62 of the catheter knob 20 is then sleeved over the second extension 52 so that the second extension 52 is received inside the hollow interior of the catheter knob 20.
  • the inner surface of the proximal end 62 of the catheter knob 20 can have threads that removably engage corresponding threads provided on the outer surface of the second extension 52.
  • the ring assembly 22 is moved in a distal direction (see arrow D in FIGS. 1 and 4A) so that the combined inner and outer rings 30, 32 are then positioned over the second extension 52 in the supporting position (see FIGS. 1 and 4B).
  • the pin 44 slides along the slot 60, but the two opposing ends of the slot 60 define the two opposing limits of movement for the ring assembly 22.
  • the transducer 25 is coupled to the sonic connector 17 using techniques that are well known in the art.
  • the combined inner and outer rings 30, 32 tightly grip and firmly engage the captured (proximal) portion 62 of the catheter knob 20 so as to provide substantial support thereto, thereby mitigating the impact of unwanted forces on the ultrasound transmission member 16.
  • the ultrasound catheter 10 is removed from the transducer housing 24 by reversing the above-described procedure.
  • the combined inner and outer rings 30, 32 are retracted in a direction opposite to the direction of the arrow D so that the combined inner and outer rings 30, 32 are now positioned over the first extension 50 against the transducer housing 24 in the non-supporting position (see FIG. 6).
  • the catheter knob 20 can then be separated from the second extension 52 by unthreading and pulling the proximal end of the catheter knob 20 from the second extension 52.

Abstract

A connector assembly connects an ultrasound transducer to an ultrasound catheter that has an ultrasound transmission member extending longitudinally therethrough. The connector assembly has an ultrasound transducer having a transducer housing, and an extension having a proximal end attached to the distal end of the transducer housing. The connector assembly also includes a ring assembly having an inner ring and an outer ring that is received inside the bore of the outer ring. The connector assembly also includes a catheter knob having a proximal end that is removably coupled to the extension. The inner ring is moved from a non-supporting position with the extension positioned inside the bore of the inner ring, to a supporting position with the catheter knob positioned inside the bore of the inner ring.

Description

CONNFCTOR FOR SECURING ULTRASOUND CATHFTFR TO TRANSDUCFR
Inventors: Henry Nita and Martinos Tran
BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention pertains to medical equipment, and more particularly, to a device and method for attaching an ultrasound catheter to an ultrasound transducer which mitigates against breakage of the ultrasound transmission member, and which facilitates ultrasound energy propagation.
2. Description of the Prior Art
A number of ultrasound systems and devices have heretofore been proposed for use in ablating or removing obstructive material from blood vessels. Ultrasound catheters have been utilized to ablate various types of obstructions from blood vessels of humans and animals. Successful applications of ultrasound energy to smaller blood vessels, such as the coronary arteries, requires the use of relatively small diameter ultrasound catheters which are sufficiently small and flexible to undergo transluminal advancement through the tortuous vasculature of the aortic arch and coronary tree. However, because of its small diameter, the ultrasound transmission member which extends through such catheters is particularly susceptible to breakage and losses in the transmitted ultrasound energy.
Breakage of ultrasound transmission members often occurs near the proximal end thereof, generally at the coupling between the ultrasound catheter coupling and the ultrasound transducer. This is believed to be because energy concentrations are highest at these points. Thus, any external forces applied to the ultrasound transmission member in this region may result in stresses exceeding the elastic limit of the ultrasound transmission member.
External forces may be inadvertently and undesirably applied to the ultrasound transmission member by pressing upon, pushing, pulling, torquing, bending or bumping the ultrasound transmission member coupling during use of the ultrasound catheter. Such forces when applied to the ultrasound catheter coupling area result in limited ultrasound energy transmission through the ultrasound transmission member. If ultrasound energy is being transmitted by the ultrasound transmission member at the instant such forces are applied thereto, stresses occur which commonly result in breakage of the ultrasound transmission member.
Thus, there still exists a need to mitigate against breakage of the ultrasound transmission member by reducing mechanical stress applied to the proximal end of the ultrasound transmission member during operation.
SUMMARY OF THE DISCLOSURE
It is an object of the present invention to provide an ultrasound catheter system that mitigates against breakage of the ultrasound transmission member by reducing mechanical stress applied to the proximal end of the ultrasound transmission member during operation.
It is another object of the present invention to provide an improved connection between the ultrasound catheter and the ultrasound transducer.
It is yet another object of the present invention to improve the propagation of ultrasound energy by limiting and minimizing impact of undesirable external forces.
In order to accomplish the objects of the present invention, there is provided a connector assembly for connecting an ultrasound transducer to an ultrasound catheter that has an ultrasound transmission member extending longitudinally therethrough. The connector assembly has an ultrasound transducer having a transducer housing, and an extension having a proximal end attached to the distal end of the transducer housing. The connector assembly also includes a ring assembly having an inner ring and an outer ring that is received inside the bore of the outer ring. The connector assembly also includes a catheter knob having a proximal end that is removably coupled to the extension. The inner ring is moved from a non- supporting position with the extension positioned inside the bore of the inner ring, to a supporting position with the catheter knob positioned inside the bore of the inner ring.
BRIEF DESCRIPTION OF THE DRAWINGS
FIG. 1 is a perspective view of an ultrasound catheter attached to an ultrasound transducer according to one embodiment of the present invention, shown with the ring assembly in the supporting position.
FIG. 2 is an exploded perspective view illustrating the various elements of the ring assembly and the transducer housing of the system of FIG. 1.
FIG. 3 is a perspective view of the ring assembly and the transducer housing of FIG. 2 shown with the ring assembly in the non-supporting position.
FIG. 4A is a cross-sectional side view taken along lines 5-5 in FIG. 3 illustrating the ring assembly in the supporting position, and also illustrating the transducer and catheter knob.
FIG. 4B is a cross-sectional side view taken along lines 5-5 in FIG. 3 illustrating the ring assembly in the non-supporting position, and also illustrating the transducer and catheter knob.
FIG. 5 is a perspective view of the ultrasound catheter and the transducer housing shown with the ring assembly in the non-supporting position.
FIG. 6 is a cross-sectional side view of the ultrasound catheter of FIG. 1.
DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS
The following detailed description is of the best presently contemplated modes of carrying out the invention. This description is not to be taken in a limiting sense, but is made merely for the purpose of illustrating general principles of embodiments of the invention. The scope of the invention is best defined by the appended claims. In certain instances, detailed descriptions of well-known devices, compositions, components, mechanisms and methods are omitted so as to not obscure the description of the present invention with unnecessary detail.
FIG. 1 illustrates an ultrasound catheter 10 that can be used for ablating and removing occlusive material inside the vessel of an animal or human being. The ultrasound catheter 10 has a proximal end 12 and a distal end 14, and defines at least one lumen 15 (see FIG. 6) extending longitudinally therethrough. An ultrasound transmission member 16 (see FIGS. 4A, 4B and 6) extends through the lumen 15 of the catheter 10 from the distal end 14 to the proximal end 12. The ultrasound catheter 10 is operatively coupled at its proximal end 12, by way of a Y-connector 18, a catheter knob 20, and a ring assembly 22, to an ultrasound transducer housing 24. An ultrasound transducer 25 is positioned inside the transducer housing 24, and is connected to a signal generator (not shown), which operates to send an electrical signal to the ultrasound transducer 25, which converts the electrical signal to ultrasound energy. The ultrasound transducer 25 is coupled via a sonic connector 17 (described in greater detail below) to the ultrasound transmission member 16, so that the ultrasound energy can be passed through the sonic connector 17 and the ultrasound transmission member 16 to be delivered to the distal end 14 of the catheter 10. A guidewire (not shown), which can be any conventional monorail or over-the-wire guidewire, may be utilized in conjunction with the catheter 10 in a manner that is well-known in the catheter art.
The frontal portion of the Y-connector 18 is connected to the proximal end 12 of the catheter 10 using techniques that are well-known in the catheter art. An injection pump (not shown) or IV bag (not shown) can be connected, by way of an infusion tube (not shown), to an infusion port or sidearm 26 of the Y-connector 18. The injection pump can be used to infuse coolant fluid (e.g., 0.9% NaCI solution) into and/or through the lumen 15 of the catheter 10. Such flow of coolant fluid may be utilized to prevent overheating of the ultrasound transmission member 16 extending longitudinally through the lumen 15. Such flow of the coolant fluid through the lumen 15 of the catheter 10 serves to bathe the outer surface of the ultrasound transmission member 16, thereby providing for an equilibration of temperature between the coolant fluid and the ultrasound transmission member 16. Thus, the temperature and/or flow rate of coolant fluid may be adjusted to provide adequate cooling and/or other temperature control of the ultrasound transmission member 16. In addition to the foregoing, the injection pump may be utilized to infuse a radiographic contrast medium into the catheter 10 for purposes of imaging. Examples of iodinated radiographic contrast media which may be selectively infused into the catheter 10 via the injection pump are commercially available as Angiovist 370 from Berlex Labs, Wayne, N.J. and Hexabrix from Malinkrodt, St. Louis, MO.
The proximal end of the ultrasound transmission member 16 is attached to a sonic connector 17 which is configured to effect operative and removable attachment of the proximal end of the ultrasound transmission member 16 to the horn 19 of the ultrasound transducer 25. The sonic connector 17 is preferably configured and constructed to permit passage of ultrasound energy through the ultrasound transmission member 16 with minimal lateral side-to-side movement of the ultrasound transmission member 16 while, at the same time, permitting unrestricted longitudinal forward/backward vibration or movement of the ultrasound transmission member 16.
The ultrasound transmission member 16 may be formed of any material capable of effectively transmitting the ultrasonic energy from the ultrasound transducer 25 to the distal end 14 of the catheter 10, including but not necessarily limited to metal, plastic, hard rubber, ceramic, fiber optics, crystal, polymers, and/or composites thereof. In accordance with one aspect of the invention, all or a portion of the ultrasound transmission member 16 may be formed of one or more materials which exhibit super-elasticity. Such materials should preferably exhibit super- elasticity consistently within the range of temperatures normally encountered by the ultrasound transmission member 16 during operation of the catheter 10. Specifically, all or part of the ultrasound transmission member 16 may be formed of one or more metal alloys known as "shape memory alloys". Such super-elastic metal alloys are well-known in the art and will not be described in any further detail herein.
The proximal end of the Y-connector 18 is attached to the distal end of the catheter knob 20 by threadably engaging the proximal end of the Y-connector 18 inside a threaded distal bore 21 at the distal end of the catheter knob 20. The proximal end of the catheter knob 20 is received by the ring assembly 22 and the distal end of the transducer housing 24. The ring assembly 22 is positioned over the distal end of the transducer housing 24, and has a non-supporting position where the ring assembly 22 is retracted towards the transducer housing 24, and has a supporting position where the ring assembly 22 is extended to engage at least a portion of the catheter knob 20. The ring assembly 22 functions as a support member that is disposed on the transducer housing 24 to support at least a portion of the catheter knob 20.
Referring to FIG. 2, the ring assembly 22 has an inner ring 30 and an outer ring 32. The inner ring 30 has a bore 34 and a longitidunal slit 38 that extends through the length of the inner ring 30. The distal portion of the bore 34 can be tapered for receiving the catheter knob 20 in a manner which more tightly grips the catheter knob 20 as the inner ring 30 is moved from the non-supporting position to the supporting position. The outer ring 32 also has a bore 36. Each of the inner ring 30 and the outer ring 32 has an opening 40 and 42, respectively, that are aligned with each other and that are adapted to receive a locking pin 44.
Referring now to FIGS. 2, 3, 4A and 4B, the transducer housing 24 has a cylindrical wall 48 having two stepped cylindrical extensions 50 and 52 extending from the distal end of the housing 48. The first extension 50 is attached to the distal end of the cylindrical wall 48, and has a greater outer diameter than the second extension 52 that is attached to the distal end of the first extension 50. A throughbore 56 extends from the hollow interior 58 of the cylindrical wall 48 and through the extensions 50 and 52. The throughbore 56 can have the same diameter throughout its length. The first extension 50 is adapted to be received inside the bore 34 of the inner ring 30, while the second extension 52 is adapted to couple the proximal end of the catheter knob 20. In particular, the catheter knob 20 can be generally cylindrical having a hollow interior so that the proximal end 62 of the catheter knob 20 can be sleeved over the second extension 52 in a manner such that the outer surface of the catheter knob 20 can be substantially flush with the outer surface of the first extension 50, as best shown in FIGS. 4A and 4B.
A longitudinal close ended slot 60 is provided on the first extension 50 for receiving the pin 44. The pin 44 extends through the openings 40, 42 and is then inserted in the slot 60, with the slot 60 defining the two limits of movement for the ring assembly 22, thereby defining the non-supporting position and the supporting position.
Thus, the ring assembly 22 functions as a support member that is disposed on the transducer housing 24 to support at least a portion of the catheter knob 20. Supporting of at least a portion of the catheter knob 20 mitigates against breakage of the ultrasound transmission member 16 by reducing mechanical stress applied to the proximal end thereof, particularly when ultrasound energy propogates through the ultrasound transmission member 16. The ring assembly 22 tends to mitigate or prevent the transmission of external forces (e.g., caused by pushing, bending, pulling, torquing or bumping the catheter knob 20) from the catheter knob 20 to the proximal end of the ultrasound transmission member 16 extending therethrough.
To use the ring assembly 22 of the present invention, the outer ring 32 is normally positioned over the inner ring 30 with the inner ring 30 seated in the bore 36 of the outer ring 32. The combined inner and outer rings 30, 32 are then positioned over the first extension 50 so that the inner and outer rings 30, 32 are positioned against the transducer housing 24 in the non-supporting position (see FIGS. 4A and 5). The proximal end 62 of the catheter knob 20 is then sleeved over the second extension 52 so that the second extension 52 is received inside the hollow interior of the catheter knob 20. In this regard, the inner surface of the proximal end 62 of the catheter knob 20 can have threads that removably engage corresponding threads provided on the outer surface of the second extension 52. At this time, the ring assembly 22 is moved in a distal direction (see arrow D in FIGS. 1 and 4A) so that the combined inner and outer rings 30, 32 are then positioned over the second extension 52 in the supporting position (see FIGS. 1 and 4B). As the ring assembly 22 is moved in a distal direction (see arrow D), the pin 44 slides along the slot 60, but the two opposing ends of the slot 60 define the two opposing limits of movement for the ring assembly 22. The transducer 25 is coupled to the sonic connector 17 using techniques that are well known in the art.
The combined inner and outer rings 30, 32 tightly grip and firmly engage the captured (proximal) portion 62 of the catheter knob 20 so as to provide substantial support thereto, thereby mitigating the impact of unwanted forces on the ultrasound transmission member 16. Upon completion of the therapeutic procedure, the ultrasound catheter 10 is removed from the transducer housing 24 by reversing the above-described procedure. In particular, the combined inner and outer rings 30, 32 are retracted in a direction opposite to the direction of the arrow D so that the combined inner and outer rings 30, 32 are now positioned over the first extension 50 against the transducer housing 24 in the non-supporting position (see FIG. 6). The catheter knob 20 can then be separated from the second extension 52 by unthreading and pulling the proximal end of the catheter knob 20 from the second extension 52.
While the description above refers to particular embodiments of the present invention, it will be understood that many modifications may be made without departing from the spirit thereof. The accompanying claims are intended to cover such modifications as would fall within the true scope and spirit of the present invention.

Claims

What is claimed is:
1. A connector assembly for connecting an ultrasound transducer to an ultrasound catheter, the connector assembly comprising: an ultrasound transducer having a transducer housing having a distal end, and an extension provided at the distal end of the transducer housing; a ring assembly having an inner ring that has a bore, and an outer ring that has a bore, with the inner ring received inside the bore of the outer ring; a catheter knob having a proximal end that is coupled to the extension; and wherein the inner ring is moved from a non-supporting position with the extension positioned inside the bore of the inner ring, to a supporting position with the catheter knob positioned inside the bore of the inner ring.
2. The assembly of claim 1 , wherein the proximal end of the catheter knob is partially positioned inside the bore of the inner ring when the inner ring is in the supporting position.
3. The assembly of claim 1 , wherein the extension has a smaller outer diameter than the transducer housing.
4. The assembly of claim 2, wherein the inner ring is positioned inside the bore of the outer ring when the inner ring is in the supporting position.
5. The assembly of claim 2, wherein the inner ring is positioned inside the bore of the outer ring when the inner ring is in the non-supporting position.
6. The assembly of claim 1 , wherein the extension has a longitudinal slot, and wherein each of the inner ring and the outer ring has an opening, with a pin extending through the opening in the inner ring and the opening in the outer ring, and traveling within the slot.
7. The assembly of claim 1 , wherein the extension comprises a first extension having a distal end and a proximal end attached to the distal end of the transducer housing, and a second extension having a distal end and a proximal end attached to the distal end of the first extension.
8. The assembly of claim 7, wherein the first extension has a greater outer diameter than the second extension.
9. An ultrasound system, comprising: a catheter having a hollow lumen therethrough, the catheter having a proximal end and a distal end; an ultrasound transducer having a transducer housing having a distal end, with a first extension having a distal end and a proximal end attached to the distal end of the transducer housing, a second extension having a distal end and a proximal end attached to the distal end of the first extension; a ring assembly having an inner ring that has a bore, and an outer ring that has a bore, with the inner ring received inside the bore of the outer ring; a catheter knob having a distal end that is attached to the proximal end of the catheter, and a proximal end that is removably coupled to the second extension; an ultrasound transmission member having a proximal end that is coupled to the transducer, the ultrasound transmission member extending through the catheter knob and the lumen of the catheter to the distal end of the catheter; and wherein the inner ring is moved from a non-supporting position with the first extension positioned inside the bore of the inner ring, to a supporting position with the second extension positioned inside the bore of the inner ring.
10. The system of claim 9, wherein the proximal end of the catheter knob is positioned inside the bore of the inner ring when the inner ring is in the supporting position.
11. The system of claim 9, wherein the first extension has a greater outer diameter than the second extension.
12. The system of claim 10, wherein the inner ring is positioned inside the bore of the outer ring when the inner ring is in the supporting position.
13. The system of claim 10, wherein the inner ring is positioned inside the bore of the outer ring when the inner ring is in the non-supporting position.
14. The system of claim 9, wherein the first extension has a longitudinal slot, and wherein each of the inner ring and the outer ring has an opening, with a pin extending through the opening in the inner ring and the opening in the outer ring, and traveling within the slot.
PCT/US2003/029632 2002-09-20 2003-09-19 Connector for securing ultrasound catheter to transducer WO2004026367A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU2003275071A AU2003275071A1 (en) 2002-09-20 2003-09-19 Connector for securing ultrasound catheter to transducer
EP03759339A EP1538988A2 (en) 2002-09-20 2003-09-19 Connector for securing ultrasound catheter to transducer

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/251,227 2002-09-20
US10/251,227 US6702748B1 (en) 2002-09-20 2002-09-20 Connector for securing ultrasound catheter to transducer

Publications (2)

Publication Number Publication Date
WO2004026367A2 true WO2004026367A2 (en) 2004-04-01
WO2004026367A3 WO2004026367A3 (en) 2005-04-07

Family

ID=31887845

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2003/029632 WO2004026367A2 (en) 2002-09-20 2003-09-19 Connector for securing ultrasound catheter to transducer

Country Status (4)

Country Link
US (1) US6702748B1 (en)
EP (1) EP1538988A2 (en)
AU (1) AU2003275071A1 (en)
WO (1) WO2004026367A2 (en)

Families Citing this family (141)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6855123B2 (en) 2002-08-02 2005-02-15 Flow Cardia, Inc. Therapeutic ultrasound system
US20040097996A1 (en) 1999-10-05 2004-05-20 Omnisonics Medical Technologies, Inc. Apparatus and method of removing occlusions using an ultrasonic medical device operating in a transverse mode
US8241274B2 (en) 2000-01-19 2012-08-14 Medtronic, Inc. Method for guiding a medical device
US8150519B2 (en) 2002-04-08 2012-04-03 Ardian, Inc. Methods and apparatus for bilateral renal neuromodulation
US7617005B2 (en) 2002-04-08 2009-11-10 Ardian, Inc. Methods and apparatus for thermally-induced renal neuromodulation
US9955994B2 (en) 2002-08-02 2018-05-01 Flowcardia, Inc. Ultrasound catheter having protective feature against breakage
US7137963B2 (en) 2002-08-26 2006-11-21 Flowcardia, Inc. Ultrasound catheter for disrupting blood vessel obstructions
US7335180B2 (en) 2003-11-24 2008-02-26 Flowcardia, Inc. Steerable ultrasound catheter
US6942677B2 (en) 2003-02-26 2005-09-13 Flowcardia, Inc. Ultrasound catheter apparatus
US7220233B2 (en) 2003-04-08 2007-05-22 Flowcardia, Inc. Ultrasound catheter devices and methods
WO2005037105A1 (en) * 2002-09-20 2005-04-28 Flowcardia, Inc. Connector for securing ultrasound catheter to transducer
US7331934B2 (en) * 2003-07-30 2008-02-19 Becton Dickinson Co Syringe assembly having disabling mechanism
DE202004021944U1 (en) 2003-09-12 2013-07-16 Vessix Vascular, Inc. Selectable eccentric remodeling and / or ablation of atherosclerotic material
US7758510B2 (en) 2003-09-19 2010-07-20 Flowcardia, Inc. Connector for securing ultrasound catheter to transducer
US7762977B2 (en) 2003-10-08 2010-07-27 Hemosphere, Inc. Device and method for vascular access
US20050137614A1 (en) * 2003-10-08 2005-06-23 Porter Christopher H. System and method for connecting implanted conduits
US7794414B2 (en) 2004-02-09 2010-09-14 Emigrant Bank, N.A. Apparatus and method for an ultrasonic medical device operating in torsional and transverse modes
US7540852B2 (en) 2004-08-26 2009-06-02 Flowcardia, Inc. Ultrasound catheter devices and methods
US9713730B2 (en) 2004-09-10 2017-07-25 Boston Scientific Scimed, Inc. Apparatus and method for treatment of in-stent restenosis
US9974607B2 (en) 2006-10-18 2018-05-22 Vessix Vascular, Inc. Inducing desirable temperature effects on body tissue
US8396548B2 (en) 2008-11-14 2013-03-12 Vessix Vascular, Inc. Selective drug delivery in a lumen
WO2006063199A2 (en) 2004-12-09 2006-06-15 The Foundry, Inc. Aortic valve repair
US8221343B2 (en) 2005-01-20 2012-07-17 Flowcardia, Inc. Vibrational catheter devices and methods for making same
IL179618A0 (en) * 2006-11-27 2007-10-31 Eyoca Medical Ltd Device for inducing vibrations
US9014786B2 (en) 2005-05-11 2015-04-21 Eyoca Medical Ltd. Device and method for opening vascular obstructions
US9282984B2 (en) * 2006-04-05 2016-03-15 Flowcardia, Inc. Therapeutic ultrasound system
US7261580B1 (en) 2006-04-27 2007-08-28 General Electric Company Cable connector
US8019435B2 (en) 2006-05-02 2011-09-13 Boston Scientific Scimed, Inc. Control of arterial smooth muscle tone
US20080039746A1 (en) 2006-05-25 2008-02-14 Medtronic, Inc. Methods of using high intensity focused ultrasound to form an ablated tissue area containing a plurality of lesions
CA2666663C (en) 2006-10-18 2016-02-09 Minnow Medical, Inc. System for inducing desirable temperature effects on body tissue
EP2455036B1 (en) 2006-10-18 2015-07-15 Vessix Vascular, Inc. Tuned RF energy and electrical tissue characterization for selective treatment of target tissues
US8246643B2 (en) 2006-11-07 2012-08-21 Flowcardia, Inc. Ultrasound catheter having improved distal end
US20110295181A1 (en) 2008-03-05 2011-12-01 Hemosphere, Inc. Implantable and removable customizable body conduit
WO2009111505A1 (en) 2008-03-05 2009-09-11 Hemosphere, Inc. Vascular access system
WO2010056745A1 (en) 2008-11-17 2010-05-20 Minnow Medical, Inc. Selective accumulation of energy with or without knowledge of tissue topography
US8226566B2 (en) 2009-06-12 2012-07-24 Flowcardia, Inc. Device and method for vascular re-entry
KR20130108067A (en) 2010-04-09 2013-10-02 베식스 바스큘라 인코포레이티드 Power generating and control apparatus for the treatment of tissue
US9192790B2 (en) 2010-04-14 2015-11-24 Boston Scientific Scimed, Inc. Focused ultrasonic renal denervation
US8473067B2 (en) 2010-06-11 2013-06-25 Boston Scientific Scimed, Inc. Renal denervation and stimulation employing wireless vascular energy transfer arrangement
US9358365B2 (en) 2010-07-30 2016-06-07 Boston Scientific Scimed, Inc. Precision electrode movement control for renal nerve ablation
US9463062B2 (en) 2010-07-30 2016-10-11 Boston Scientific Scimed, Inc. Cooled conductive balloon RF catheter for renal nerve ablation
US9084609B2 (en) 2010-07-30 2015-07-21 Boston Scientific Scime, Inc. Spiral balloon catheter for renal nerve ablation
US9155589B2 (en) 2010-07-30 2015-10-13 Boston Scientific Scimed, Inc. Sequential activation RF electrode set for renal nerve ablation
US9408661B2 (en) 2010-07-30 2016-08-09 Patrick A. Haverkost RF electrodes on multiple flexible wires for renal nerve ablation
US8974451B2 (en) 2010-10-25 2015-03-10 Boston Scientific Scimed, Inc. Renal nerve ablation using conductive fluid jet and RF energy
US9220558B2 (en) 2010-10-27 2015-12-29 Boston Scientific Scimed, Inc. RF renal denervation catheter with multiple independent electrodes
US9028485B2 (en) 2010-11-15 2015-05-12 Boston Scientific Scimed, Inc. Self-expanding cooling electrode for renal nerve ablation
US9668811B2 (en) 2010-11-16 2017-06-06 Boston Scientific Scimed, Inc. Minimally invasive access for renal nerve ablation
US9089350B2 (en) 2010-11-16 2015-07-28 Boston Scientific Scimed, Inc. Renal denervation catheter with RF electrode and integral contrast dye injection arrangement
US9326751B2 (en) 2010-11-17 2016-05-03 Boston Scientific Scimed, Inc. Catheter guidance of external energy for renal denervation
US9060761B2 (en) 2010-11-18 2015-06-23 Boston Scientific Scime, Inc. Catheter-focused magnetic field induced renal nerve ablation
US9023034B2 (en) 2010-11-22 2015-05-05 Boston Scientific Scimed, Inc. Renal ablation electrode with force-activatable conduction apparatus
US9192435B2 (en) 2010-11-22 2015-11-24 Boston Scientific Scimed, Inc. Renal denervation catheter with cooled RF electrode
US20120157993A1 (en) 2010-12-15 2012-06-21 Jenson Mark L Bipolar Off-Wall Electrode Device for Renal Nerve Ablation
WO2012087842A1 (en) 2010-12-23 2012-06-28 The Foundry, Llc System for mitral valve repair and replacement
US9220561B2 (en) 2011-01-19 2015-12-29 Boston Scientific Scimed, Inc. Guide-compatible large-electrode catheter for renal nerve ablation with reduced arterial injury
JP5872692B2 (en) 2011-06-21 2016-03-01 トゥエルヴ, インコーポレイテッド Artificial therapy device
WO2013013156A2 (en) 2011-07-20 2013-01-24 Boston Scientific Scimed, Inc. Percutaneous devices and methods to visualize, target and ablate nerves
JP6106669B2 (en) 2011-07-22 2017-04-05 ボストン サイエンティフィック サイムド,インコーポレイテッドBoston Scientific Scimed,Inc. A neuromodulation system having a neuromodulation element that can be placed in a helical guide
CN103813817A (en) 2011-09-06 2014-05-21 海默斯菲尔有限公司 Vascular access system with connector
EP2765942B1 (en) 2011-10-10 2016-02-24 Boston Scientific Scimed, Inc. Medical devices including ablation electrodes
US9420955B2 (en) 2011-10-11 2016-08-23 Boston Scientific Scimed, Inc. Intravascular temperature monitoring system and method
EP2765940B1 (en) 2011-10-11 2015-08-26 Boston Scientific Scimed, Inc. Off-wall electrode device for nerve modulation
US9364284B2 (en) 2011-10-12 2016-06-14 Boston Scientific Scimed, Inc. Method of making an off-wall spacer cage
EP2768568B1 (en) 2011-10-18 2020-05-06 Boston Scientific Scimed, Inc. Integrated crossing balloon catheter
EP2768563B1 (en) 2011-10-18 2016-11-09 Boston Scientific Scimed, Inc. Deflectable medical devices
US11202704B2 (en) 2011-10-19 2021-12-21 Twelve, Inc. Prosthetic heart valve devices, prosthetic mitral valves and associated systems and methods
US9763780B2 (en) 2011-10-19 2017-09-19 Twelve, Inc. Devices, systems and methods for heart valve replacement
US9655722B2 (en) 2011-10-19 2017-05-23 Twelve, Inc. Prosthetic heart valve devices, prosthetic mitral valves and associated systems and methods
AU2012325809B2 (en) 2011-10-19 2016-01-21 Twelve, Inc. Devices, systems and methods for heart valve replacement
CA3090422C (en) 2011-10-19 2023-08-01 Twelve, Inc. Prosthetic heart valve devices, prosthetic mitral valves and associated systems and methods
US9039757B2 (en) 2011-10-19 2015-05-26 Twelve, Inc. Prosthetic heart valve devices, prosthetic mitral valves and associated systems and methods
WO2013070724A1 (en) 2011-11-08 2013-05-16 Boston Scientific Scimed, Inc. Ostial renal nerve ablation
EP2779929A1 (en) 2011-11-15 2014-09-24 Boston Scientific Scimed, Inc. Device and methods for renal nerve modulation monitoring
US9119632B2 (en) 2011-11-21 2015-09-01 Boston Scientific Scimed, Inc. Deflectable renal nerve ablation catheter
US9265969B2 (en) 2011-12-21 2016-02-23 Cardiac Pacemakers, Inc. Methods for modulating cell function
WO2013096920A1 (en) 2011-12-23 2013-06-27 Vessix Vascular, Inc. Methods and apparatuses for remodeling tissue of or adjacent to a body passage
WO2013101452A1 (en) 2011-12-28 2013-07-04 Boston Scientific Scimed, Inc. Device and methods for nerve modulation using a novel ablation catheter with polymeric ablative elements
US9050106B2 (en) 2011-12-29 2015-06-09 Boston Scientific Scimed, Inc. Off-wall electrode device and methods for nerve modulation
WO2013109269A1 (en) 2012-01-18 2013-07-25 Bard Peripheral Vascular, Inc. Vascular re-entry device
US9579198B2 (en) 2012-03-01 2017-02-28 Twelve, Inc. Hydraulic delivery systems for prosthetic heart valve devices and associated methods
US10660703B2 (en) 2012-05-08 2020-05-26 Boston Scientific Scimed, Inc. Renal nerve modulation devices
US10238895B2 (en) 2012-08-02 2019-03-26 Flowcardia, Inc. Ultrasound catheter system
US10321946B2 (en) 2012-08-24 2019-06-18 Boston Scientific Scimed, Inc. Renal nerve modulation devices with weeping RF ablation balloons
CN104780859B (en) 2012-09-17 2017-07-25 波士顿科学西美德公司 Self-positioning electrode system and method for renal regulation
US10398464B2 (en) 2012-09-21 2019-09-03 Boston Scientific Scimed, Inc. System for nerve modulation and innocuous thermal gradient nerve block
US10549127B2 (en) 2012-09-21 2020-02-04 Boston Scientific Scimed, Inc. Self-cooling ultrasound ablation catheter
CN104869930B (en) 2012-10-10 2020-12-25 波士顿科学国际有限公司 Renal neuromodulation apparatus and methods
US10245051B2 (en) 2012-12-28 2019-04-02 Bard Peripheral Vascular, Inc. Drug delivery via mechanical vibration balloon
WO2014163987A1 (en) 2013-03-11 2014-10-09 Boston Scientific Scimed, Inc. Medical devices for modulating nerves
US9693821B2 (en) 2013-03-11 2017-07-04 Boston Scientific Scimed, Inc. Medical devices for modulating nerves
US9808311B2 (en) 2013-03-13 2017-11-07 Boston Scientific Scimed, Inc. Deflectable medical devices
EP2967734B1 (en) 2013-03-15 2019-05-15 Boston Scientific Scimed, Inc. Methods and apparatuses for remodeling tissue of or adjacent to a body passage
WO2014149690A2 (en) 2013-03-15 2014-09-25 Boston Scientific Scimed, Inc. Medical devices and methods for treatment of hypertension that utilize impedance compensation
US10265122B2 (en) 2013-03-15 2019-04-23 Boston Scientific Scimed, Inc. Nerve ablation devices and related methods of use
US10111747B2 (en) 2013-05-20 2018-10-30 Twelve, Inc. Implantable heart valve devices, mitral valve repair devices and associated systems and methods
JP2016523147A (en) 2013-06-21 2016-08-08 ボストン サイエンティフィック サイムド,インコーポレイテッドBoston Scientific Scimed,Inc. Renal denervation balloon catheter with a riding-type electrode support
CN105473092B (en) 2013-06-21 2019-05-17 波士顿科学国际有限公司 The medical instrument for renal nerve ablation with rotatable shaft
US9707036B2 (en) 2013-06-25 2017-07-18 Boston Scientific Scimed, Inc. Devices and methods for nerve modulation using localized indifferent electrodes
AU2014284558B2 (en) 2013-07-01 2017-08-17 Boston Scientific Scimed, Inc. Medical devices for renal nerve ablation
WO2015006573A1 (en) 2013-07-11 2015-01-15 Boston Scientific Scimed, Inc. Medical device with stretchable electrode assemblies
US10660698B2 (en) 2013-07-11 2020-05-26 Boston Scientific Scimed, Inc. Devices and methods for nerve modulation
CN105682594B (en) 2013-07-19 2018-06-22 波士顿科学国际有限公司 Helical bipolar electrodes renal denervation dominates air bag
EP3024406B1 (en) 2013-07-22 2019-06-19 Boston Scientific Scimed, Inc. Medical devices for renal nerve ablation
JP6122217B2 (en) 2013-07-22 2017-04-26 ボストン サイエンティフィック サイムド,インコーポレイテッドBoston Scientific Scimed,Inc. Renal nerve ablation medical device
US10722300B2 (en) 2013-08-22 2020-07-28 Boston Scientific Scimed, Inc. Flexible circuit having improved adhesion to a renal nerve modulation balloon
EP3041425B1 (en) 2013-09-04 2022-04-13 Boston Scientific Scimed, Inc. Radio frequency (rf) balloon catheter having flushing and cooling capability
WO2015038947A1 (en) 2013-09-13 2015-03-19 Boston Scientific Scimed, Inc. Ablation balloon with vapor deposited cover layer
US11246654B2 (en) 2013-10-14 2022-02-15 Boston Scientific Scimed, Inc. Flexible renal nerve ablation devices and related methods of use and manufacture
CN105592778B (en) 2013-10-14 2019-07-23 波士顿科学医学有限公司 High-resolution cardiac mapping electrod-array conduit
US9770606B2 (en) 2013-10-15 2017-09-26 Boston Scientific Scimed, Inc. Ultrasound ablation catheter with cooling infusion and centering basket
CN105636537B (en) 2013-10-15 2018-08-17 波士顿科学国际有限公司 Medical instrument sacculus
WO2015057961A1 (en) 2013-10-18 2015-04-23 Boston Scientific Scimed, Inc. Balloon catheters with flexible conducting wires and related methods of use and manufacture
WO2015061457A1 (en) 2013-10-25 2015-04-30 Boston Scientific Scimed, Inc. Embedded thermocouple in denervation flex circuit
WO2015094514A1 (en) 2013-12-20 2015-06-25 Cryolife, Inc. Vascular access system with reinforcement member
JP6382989B2 (en) 2014-01-06 2018-08-29 ボストン サイエンティフィック サイムド,インコーポレイテッドBoston Scientific Scimed,Inc. Medical device with tear resistant flexible circuit assembly
CN106572881B (en) 2014-02-04 2019-07-26 波士顿科学国际有限公司 Substitution of the heat sensor on bipolar electrode is placed
US11000679B2 (en) 2014-02-04 2021-05-11 Boston Scientific Scimed, Inc. Balloon protection and rewrapping devices and related methods of use
US10238490B2 (en) 2015-08-21 2019-03-26 Twelve, Inc. Implant heart valve devices, mitral valve repair devices and associated systems and methods
CN116172753A (en) 2016-04-29 2023-05-30 美敦力瓦斯科尔勒公司 Prosthetic heart valve devices having tethered anchors and associated systems and methods
EP3537992B1 (en) 2016-11-10 2021-08-18 Merit Medical Systems, Inc. Anchor device for vascular anastomosis
US20180140321A1 (en) 2016-11-23 2018-05-24 C. R. Bard, Inc. Catheter With Retractable Sheath And Methods Thereof
US11596726B2 (en) 2016-12-17 2023-03-07 C.R. Bard, Inc. Ultrasound devices for removing clots from catheters and related methods
US10758256B2 (en) 2016-12-22 2020-09-01 C. R. Bard, Inc. Ultrasonic endovascular catheter
US11383072B2 (en) 2017-01-12 2022-07-12 Merit Medical Systems, Inc. Methods and systems for selection and use of connectors between conduits
US11590010B2 (en) 2017-01-25 2023-02-28 Merit Medical Systems, Inc. Methods and systems for facilitating laminar flow between conduits
US10582983B2 (en) 2017-02-06 2020-03-10 C. R. Bard, Inc. Ultrasonic endovascular catheter with a controllable sheath
US11026704B2 (en) 2017-03-06 2021-06-08 Merit Medical Systems, Inc. Vascular access assembly declotting systems and methods
WO2018175850A1 (en) 2017-03-24 2018-09-27 Merit Medical Systems, Inc. Subcutaneous vascular assemblies for improving blood flow and related devices and methods
US10702378B2 (en) 2017-04-18 2020-07-07 Twelve, Inc. Prosthetic heart valve device and associated systems and methods
US10575950B2 (en) 2017-04-18 2020-03-03 Twelve, Inc. Hydraulic systems for delivering prosthetic heart valve devices and associated methods
US10433961B2 (en) 2017-04-18 2019-10-08 Twelve, Inc. Delivery systems with tethers for prosthetic heart valve devices and associated methods
US10792151B2 (en) 2017-05-11 2020-10-06 Twelve, Inc. Delivery systems for delivering prosthetic heart valve devices and associated methods
US10646338B2 (en) 2017-06-02 2020-05-12 Twelve, Inc. Delivery systems with telescoping capsules for deploying prosthetic heart valve devices and associated methods
US10709591B2 (en) 2017-06-06 2020-07-14 Twelve, Inc. Crimping device and method for loading stents and prosthetic heart valves
US10729541B2 (en) 2017-07-06 2020-08-04 Twelve, Inc. Prosthetic heart valve devices and associated systems and methods
US10786352B2 (en) 2017-07-06 2020-09-29 Twelve, Inc. Prosthetic heart valve devices and associated systems and methods
EP3651829A4 (en) 2017-07-14 2021-04-21 Merit Medical Systems, Inc. Releasable conduit connectors
US11911585B2 (en) 2017-07-20 2024-02-27 Merit Medical Systems, Inc. Methods and systems for coupling conduits
WO2019089569A1 (en) 2017-10-31 2019-05-09 Merit Medical Systems, Inc. Subcutaneous vascular assemblies for improving blood flow and related devices and methods
EP4126182A4 (en) * 2020-03-31 2024-03-20 Dib UltraNav Medical LLC Handle assembly for medical devices

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5989208A (en) * 1997-05-16 1999-11-23 Nita; Henry Therapeutic ultrasound system

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5417672A (en) 1993-10-04 1995-05-23 Baxter International Inc. Connector for coupling an ultrasound transducer to an ultrasound catheter

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5989208A (en) * 1997-05-16 1999-11-23 Nita; Henry Therapeutic ultrasound system

Also Published As

Publication number Publication date
AU2003275071A1 (en) 2004-04-08
AU2003275071A8 (en) 2004-04-08
WO2004026367A3 (en) 2005-04-07
US6702748B1 (en) 2004-03-09
EP1538988A2 (en) 2005-06-15

Similar Documents

Publication Publication Date Title
US6702748B1 (en) Connector for securing ultrasound catheter to transducer
US11426189B2 (en) Connector for securing ultrasound catheter to transducer
US6942620B2 (en) Connector for securing ultrasound catheter to transducer
US8133236B2 (en) Ultrasound catheter having protective feature against breakage
US10835267B2 (en) Ultrasound catheter having protective feature against breakage
US9282984B2 (en) Therapeutic ultrasound system
EP2298194B1 (en) Therapeutic ultrasound system
EP2417920B1 (en) Therapeutic ultrasound system
EP1545344B1 (en) Therapeutic ultrasound system
US8506519B2 (en) Pre-shaped therapeutic catheter
EP1663008B1 (en) Connector for securing ultrasound catheter to transducer

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SY TJ TM TN TR TT TZ UA UG UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LU MC NL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
WWE Wipo information: entry into national phase

Ref document number: 2003759339

Country of ref document: EP

WWP Wipo information: published in national office

Ref document number: 2003759339

Country of ref document: EP

NENP Non-entry into the national phase

Ref country code: JP

WWW Wipo information: withdrawn in national office

Country of ref document: JP