WO2004041183A3 - Methods of treating pulmonary fibrotic disorders - Google Patents
Methods of treating pulmonary fibrotic disorders Download PDFInfo
- Publication number
- WO2004041183A3 WO2004041183A3 PCT/US2003/034582 US0334582W WO2004041183A3 WO 2004041183 A3 WO2004041183 A3 WO 2004041183A3 US 0334582 W US0334582 W US 0334582W WO 2004041183 A3 WO2004041183 A3 WO 2004041183A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- methods
- treating pulmonary
- present
- fibrotic disorders
- pulmonary fibrotic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/117—Nucleic acids having immunomodulatory properties, e.g. containing CpG-motifs
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/111—General methods applicable to biologically active non-coding nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/17—Immunomodulatory nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/31—Chemical structure of the backbone
- C12N2310/315—Phosphorothioates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2320/00—Applications; Uses
- C12N2320/30—Special therapeutic applications
- C12N2320/31—Combination therapy
Abstract
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2003287332A AU2003287332A1 (en) | 2002-11-01 | 2003-10-29 | Methods of treating pulmonary fibrotic disorders |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US42303502P | 2002-11-01 | 2002-11-01 | |
US60/423,035 | 2002-11-01 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2004041183A2 WO2004041183A2 (en) | 2004-05-21 |
WO2004041183A3 true WO2004041183A3 (en) | 2004-06-24 |
Family
ID=32312592
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2003/034582 WO2004041183A2 (en) | 2002-11-01 | 2003-10-29 | Methods of treating pulmonary fibrotic disorders |
Country Status (3)
Country | Link |
---|---|
US (1) | US20040248837A1 (en) |
AU (1) | AU2003287332A1 (en) |
WO (1) | WO2004041183A2 (en) |
Families Citing this family (52)
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US7935675B1 (en) | 1994-07-15 | 2011-05-03 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
US6207646B1 (en) | 1994-07-15 | 2001-03-27 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
US20030022854A1 (en) | 1998-06-25 | 2003-01-30 | Dow Steven W. | Vaccines using nucleic acid-lipid complexes |
AR040996A1 (en) | 2002-08-19 | 2005-04-27 | Coley Pharm Group Inc | IMMUNE STIMULATING NUCLEIC ACIDS |
CA2502015A1 (en) | 2002-12-11 | 2004-06-24 | Coley Pharmaceutical Group, Inc. | 5' cpg nucleic acids and methods of use |
JP4891066B2 (en) * | 2003-03-13 | 2012-03-07 | スリーエム イノベイティブ プロパティズ カンパニー | How to improve skin quality |
US7521459B2 (en) * | 2003-07-28 | 2009-04-21 | Metabeauty Inc. | Method for treating damaged skin |
FR2863890B1 (en) * | 2003-12-19 | 2006-03-24 | Aventis Pasteur | IMMUNOSTIMULATING COMPOSITION |
WO2006080946A2 (en) * | 2004-06-08 | 2006-08-03 | Coley Pharmaceutical Gmbh | Abasic oligonucleotide as carrier platform for antigen and immunostimulatory agonist and antagonist |
US7482158B2 (en) * | 2004-07-01 | 2009-01-27 | Mathison Brian H | Composite polynucleic acid therapeutics |
US8078266B2 (en) | 2005-10-25 | 2011-12-13 | Voyage Medical, Inc. | Flow reduction hood systems |
US7860555B2 (en) | 2005-02-02 | 2010-12-28 | Voyage Medical, Inc. | Tissue visualization and manipulation system |
US10064540B2 (en) | 2005-02-02 | 2018-09-04 | Intuitive Surgical Operations, Inc. | Visualization apparatus for transseptal access |
US7860556B2 (en) | 2005-02-02 | 2010-12-28 | Voyage Medical, Inc. | Tissue imaging and extraction systems |
US7918787B2 (en) | 2005-02-02 | 2011-04-05 | Voyage Medical, Inc. | Tissue visualization and manipulation systems |
US11478152B2 (en) | 2005-02-02 | 2022-10-25 | Intuitive Surgical Operations, Inc. | Electrophysiology mapping and visualization system |
US9510732B2 (en) | 2005-10-25 | 2016-12-06 | Intuitive Surgical Operations, Inc. | Methods and apparatus for efficient purging |
US8137333B2 (en) * | 2005-10-25 | 2012-03-20 | Voyage Medical, Inc. | Delivery of biological compounds to ischemic and/or infarcted tissue |
US8050746B2 (en) | 2005-02-02 | 2011-11-01 | Voyage Medical, Inc. | Tissue visualization device and method variations |
US20080015569A1 (en) | 2005-02-02 | 2008-01-17 | Voyage Medical, Inc. | Methods and apparatus for treatment of atrial fibrillation |
US7930016B1 (en) | 2005-02-02 | 2011-04-19 | Voyage Medical, Inc. | Tissue closure system |
US8221310B2 (en) | 2005-10-25 | 2012-07-17 | Voyage Medical, Inc. | Tissue visualization device and method variations |
US9055906B2 (en) | 2006-06-14 | 2015-06-16 | Intuitive Surgical Operations, Inc. | In-vivo visualization systems |
US10004388B2 (en) | 2006-09-01 | 2018-06-26 | Intuitive Surgical Operations, Inc. | Coronary sinus cannulation |
US20080097476A1 (en) | 2006-09-01 | 2008-04-24 | Voyage Medical, Inc. | Precision control systems for tissue visualization and manipulation assemblies |
JP2010502313A (en) | 2006-09-01 | 2010-01-28 | ボエッジ メディカル, インコーポレイテッド | Method and apparatus for the treatment of atrial fibrillation |
US20100256085A1 (en) * | 2006-10-16 | 2010-10-07 | Yale University | Toll-Like Receptor Agonist Regulation of VEGF-Induced Tissue Responses |
US20110245323A1 (en) * | 2006-10-16 | 2011-10-06 | Yale University | RIG-Like Helicase Innate Immunity Inhibits VEGF-Induced Tissue Responses |
US10335131B2 (en) | 2006-10-23 | 2019-07-02 | Intuitive Surgical Operations, Inc. | Methods for preventing tissue migration |
US20080183036A1 (en) | 2006-12-18 | 2008-07-31 | Voyage Medical, Inc. | Systems and methods for unobstructed visualization and ablation |
US9226648B2 (en) | 2006-12-21 | 2016-01-05 | Intuitive Surgical Operations, Inc. | Off-axis visualization systems |
US8131350B2 (en) | 2006-12-21 | 2012-03-06 | Voyage Medical, Inc. | Stabilization of visualization catheters |
EP2148608A4 (en) | 2007-04-27 | 2010-04-28 | Voyage Medical Inc | Complex shape steerable tissue visualization and manipulation catheter |
US8657805B2 (en) | 2007-05-08 | 2014-02-25 | Intuitive Surgical Operations, Inc. | Complex shape steerable tissue visualization and manipulation catheter |
US8709008B2 (en) | 2007-05-11 | 2014-04-29 | Intuitive Surgical Operations, Inc. | Visual electrode ablation systems |
US8235985B2 (en) | 2007-08-31 | 2012-08-07 | Voyage Medical, Inc. | Visualization and ablation system variations |
US8858609B2 (en) | 2008-02-07 | 2014-10-14 | Intuitive Surgical Operations, Inc. | Stent delivery under direct visualization |
US9101735B2 (en) | 2008-07-07 | 2015-08-11 | Intuitive Surgical Operations, Inc. | Catheter control systems |
US8894643B2 (en) | 2008-10-10 | 2014-11-25 | Intuitive Surgical Operations, Inc. | Integral electrode placement and connection systems |
US8333012B2 (en) | 2008-10-10 | 2012-12-18 | Voyage Medical, Inc. | Method of forming electrode placement and connection systems |
US9468364B2 (en) | 2008-11-14 | 2016-10-18 | Intuitive Surgical Operations, Inc. | Intravascular catheter with hood and image processing systems |
KR101856462B1 (en) | 2009-03-25 | 2018-05-10 | 보드 오브 리전츠, 더 유니버시티 오브 텍사스 시스템 | Compositions for stimulation of mammalian innate immune resistance to pathogens |
US8694071B2 (en) | 2010-02-12 | 2014-04-08 | Intuitive Surgical Operations, Inc. | Image stabilization techniques and methods |
US9814522B2 (en) | 2010-04-06 | 2017-11-14 | Intuitive Surgical Operations, Inc. | Apparatus and methods for ablation efficacy |
US20140315210A1 (en) * | 2011-12-21 | 2014-10-23 | University College Dublin, National University Of Ireland, Dublin | Methods relating to idiopathic pulmonary fibrosis (ipf) |
IN2014MN02359A (en) * | 2012-05-03 | 2015-08-14 | Janssen R & D Ireland | |
US9919029B2 (en) | 2013-07-26 | 2018-03-20 | Inserm (Institut National De La Sante Et De La Recherche Medicale) | Methods and pharmaceutical compositions for the treatment of bacterial infections |
WO2016044839A2 (en) | 2014-09-19 | 2016-03-24 | The Board Of Regents Of The University Of Texas System | Compositions and methods for treating viral infections through stimulated innate immunity in combination with antiviral compounds |
WO2016180852A1 (en) | 2015-05-12 | 2016-11-17 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods for preparing antigen-specific t cells from an umbilical cord blood sample |
LU92821B1 (en) | 2015-09-09 | 2017-03-20 | Mologen Ag | Combination comprising immunostimulatory oligonucleotides |
GB2542425A (en) | 2015-09-21 | 2017-03-22 | Mologen Ag | Means for the treatment of HIV |
EP3392345A1 (en) * | 2017-04-22 | 2018-10-24 | Mologen AG | Biomarker for small cell lung cancer therapy |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5192528A (en) * | 1985-05-22 | 1993-03-09 | Liposome Technology, Inc. | Corticosteroid inhalation treatment method |
WO1998037919A1 (en) * | 1997-02-28 | 1998-09-03 | University Of Iowa Research Foundation | USE OF NUCLEIC ACIDS CONTAINING UNMETHYLATED CpG DINUCLEOTIDE IN THE TREATMENT OF LPS-ASSOCIATED DISORDERS |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5849719A (en) * | 1993-08-26 | 1998-12-15 | The Regents Of The University Of California | Method for treating allergic lung disease |
CA2302805A1 (en) * | 1997-09-05 | 1999-03-11 | The Regents Of The University Of California | Use of immunostimulatory oligonucleotides for preventing or reducing antigen-stimulated, granulocyte-mediated inflammation |
US20040241149A1 (en) * | 2001-09-05 | 2004-12-02 | Claudio De Simone | Use of unmethylatd cpg |
US20030139364A1 (en) * | 2001-10-12 | 2003-07-24 | University Of Iowa Research Foundation | Methods and products for enhancing immune responses using imidazoquinoline compounds |
-
2003
- 2003-10-29 AU AU2003287332A patent/AU2003287332A1/en not_active Abandoned
- 2003-10-29 WO PCT/US2003/034582 patent/WO2004041183A2/en not_active Application Discontinuation
- 2003-10-29 US US10/697,817 patent/US20040248837A1/en not_active Abandoned
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5192528A (en) * | 1985-05-22 | 1993-03-09 | Liposome Technology, Inc. | Corticosteroid inhalation treatment method |
WO1998037919A1 (en) * | 1997-02-28 | 1998-09-03 | University Of Iowa Research Foundation | USE OF NUCLEIC ACIDS CONTAINING UNMETHYLATED CpG DINUCLEOTIDE IN THE TREATMENT OF LPS-ASSOCIATED DISORDERS |
Non-Patent Citations (2)
Title |
---|
JAIN V.V. ET AL.: "CpG-oligodeoxynucleotides inhibit airway remodeling in a murine model of chronic asthma", JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, vol. 110, no. 6, December 2002 (2002-12-01), pages 867 - 872, XP002976934 * |
JUFFERMANS N.P. ET AL.: "CpG oligodeoxynucleotides enhance host defense during murine tuberculosis", INFECTION AND IMMUNITY, vol. 70, no. 1, January 2002 (2002-01-01), pages 147 - 152, XP002976933 * |
Also Published As
Publication number | Publication date |
---|---|
WO2004041183A2 (en) | 2004-05-21 |
AU2003287332A1 (en) | 2004-06-07 |
AU2003287332A8 (en) | 2004-06-07 |
US20040248837A1 (en) | 2004-12-09 |
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