WO2004055491A3 - Novel method for sequence determination using nmr - Google Patents

Novel method for sequence determination using nmr Download PDF

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Publication number
WO2004055491A3
WO2004055491A3 PCT/US2003/015850 US0315850W WO2004055491A3 WO 2004055491 A3 WO2004055491 A3 WO 2004055491A3 US 0315850 W US0315850 W US 0315850W WO 2004055491 A3 WO2004055491 A3 WO 2004055491A3
Authority
WO
WIPO (PCT)
Prior art keywords
nmr
novel method
sequence determination
polysaccharides
methods
Prior art date
Application number
PCT/US2003/015850
Other languages
French (fr)
Other versions
WO2004055491A8 (en
WO2004055491A2 (en
Inventor
Ram Sasisekharan
Ganesh Venkataraman
Rahul Raman
Benito Casu
Giangiacomo Torri
Marco Guerrini
Original Assignee
Massachusetts Inst Technology
Istituto G Ronzoni
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Massachusetts Inst Technology, Istituto G Ronzoni filed Critical Massachusetts Inst Technology
Priority to JP2004560266A priority Critical patent/JP4657726B2/en
Priority to CA2486456A priority patent/CA2486456C/en
Priority to EP03810037A priority patent/EP1590648A4/en
Priority to AU2003302219A priority patent/AU2003302219B8/en
Publication of WO2004055491A2 publication Critical patent/WO2004055491A2/en
Publication of WO2004055491A3 publication Critical patent/WO2004055491A3/en
Publication of WO2004055491A8 publication Critical patent/WO2004055491A8/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N24/00—Investigating or analyzing materials by the use of nuclear magnetic resonance, electron paramagnetic resonance or other spin effects
    • G01N24/08—Investigating or analyzing materials by the use of nuclear magnetic resonance, electron paramagnetic resonance or other spin effects by using nuclear magnetic resonance
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333—Saccharide [e.g., DNA, etc.]

Abstract

The invention relates to methods for analyzing polysaccharides. In particular, compositional and sequence information about the polysaccharides are derived (figure 1). Some methods use NMR in conjunction with another experimental method, such as, capillary electrophoretic techniques for the analysis (figures 2 & 3).
PCT/US2003/015850 2002-05-20 2003-05-20 Novel method for sequence determination using nmr WO2004055491A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP2004560266A JP4657726B2 (en) 2002-05-20 2003-05-20 A novel method for sequencing using NMR
CA2486456A CA2486456C (en) 2002-05-20 2003-05-20 Method for sequence determination using nmr
EP03810037A EP1590648A4 (en) 2002-05-20 2003-05-20 Novel method for sequence determination using nmr
AU2003302219A AU2003302219B8 (en) 2002-05-20 2003-05-20 Novel method for sequence determination using NMR

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US38194002P 2002-05-20 2002-05-20
US60/381,940 2002-05-20

Publications (3)

Publication Number Publication Date
WO2004055491A2 WO2004055491A2 (en) 2004-07-01
WO2004055491A3 true WO2004055491A3 (en) 2007-04-05
WO2004055491A8 WO2004055491A8 (en) 2007-05-18

Family

ID=32595013

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2003/015850 WO2004055491A2 (en) 2002-05-20 2003-05-20 Novel method for sequence determination using nmr

Country Status (6)

Country Link
US (4) US7508206B2 (en)
EP (1) EP1590648A4 (en)
JP (2) JP4657726B2 (en)
AU (1) AU2003302219B8 (en)
CA (1) CA2486456C (en)
WO (1) WO2004055491A2 (en)

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CN102206690A (en) * 2011-03-13 2011-10-05 广元市海鹏生物科技有限公司 Preparation method of heparin oligosaccharides
CN106093379A (en) * 2016-06-08 2016-11-09 中国科学院广州生物医药与健康研究院 A kind of semicarbazides derivatization reagent and rapid detection card thereof
EP3273239A1 (en) 2016-07-19 2018-01-24 Laboratorios Farmacéuticos Rovi, S.A. Procedure of analysis of glycosaminoglycans, heparins and their derivatives by nuclear magnetic resonance
CN110376235B (en) * 2019-07-18 2020-09-15 浙江大学 Space correlation spectrum testing method of cephalomannine based on nuclear magnetic resonance technology
WO2022115339A1 (en) * 2020-11-24 2022-06-02 The Johns Hopkins University Magnetic resonance imaging of glycogen and other polysaccharides by magnetic coupling with water

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US5284558A (en) * 1990-07-27 1994-02-08 University Of Iowa Research Foundation Electrophoresis-based sequencing of oligosaccharides
US6190522B1 (en) * 1998-04-24 2001-02-20 Board Of Regents, The University Of Texas System Analysis of carbohydrates derivatized with visible dye by high-resolution polyacrylamide gel electrophoresis

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Also Published As

Publication number Publication date
AU2003302219A1 (en) 2004-07-09
WO2004055491A8 (en) 2007-05-18
US8018231B2 (en) 2011-09-13
US20040092037A1 (en) 2004-05-13
JP2006505799A (en) 2006-02-16
AU2003302219B8 (en) 2009-03-26
US20080278164A1 (en) 2008-11-13
US20090045811A1 (en) 2009-02-19
US7728589B2 (en) 2010-06-01
WO2004055491A2 (en) 2004-07-01
EP1590648A2 (en) 2005-11-02
CA2486456A1 (en) 2004-07-01
JP2009300452A (en) 2009-12-24
US7508206B2 (en) 2009-03-24
EP1590648A4 (en) 2007-04-18
AU2003302219B2 (en) 2009-02-19
CA2486456C (en) 2012-07-17
US7737692B2 (en) 2010-06-15
JP4657726B2 (en) 2011-03-23
US20100216176A1 (en) 2010-08-26

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