WO2004069331A3 - Neural stimulation - Google Patents

Neural stimulation Download PDF

Info

Publication number
WO2004069331A3
WO2004069331A3 PCT/US2004/002847 US2004002847W WO2004069331A3 WO 2004069331 A3 WO2004069331 A3 WO 2004069331A3 US 2004002847 W US2004002847 W US 2004002847W WO 2004069331 A3 WO2004069331 A3 WO 2004069331A3
Authority
WO
WIPO (PCT)
Prior art keywords
blocking
electrodes
disorders
neural stimulation
neural
Prior art date
Application number
PCT/US2004/002847
Other languages
French (fr)
Other versions
WO2004069331B1 (en
WO2004069331A2 (en
Inventor
Mark B Knudson
Timothy R Conrad
Luke B Evnin
Richard R Wilson
Katherine S Tweden
Original Assignee
Enteromedics Inc
Mark B Knudson
Timothy R Conrad
Luke B Evnin
Richard R Wilson
Katherine S Tweden
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/358,093 external-priority patent/US20040172084A1/en
Application filed by Enteromedics Inc, Mark B Knudson, Timothy R Conrad, Luke B Evnin, Richard R Wilson, Katherine S Tweden filed Critical Enteromedics Inc
Priority to DK04707122.0T priority Critical patent/DK1601414T3/en
Priority to AT04707122T priority patent/ATE547148T1/en
Priority to EP04707122A priority patent/EP1601414B1/en
Publication of WO2004069331A2 publication Critical patent/WO2004069331A2/en
Publication of WO2004069331A3 publication Critical patent/WO2004069331A3/en
Publication of WO2004069331B1 publication Critical patent/WO2004069331B1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36053—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for vagal stimulation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F5/00—Orthopaedic methods or devices for non-surgical treatment of bones or joints; Nursing devices; Anti-rape devices
    • A61F5/0003—Apparatus for the treatment of obesity; Anti-eating devices
    • A61F5/0013—Implantable devices or invasive measures
    • A61F5/0026—Anti-eating devices using electrical stimulation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/321—Electromedical belts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36007—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation of urogenital or gastrointestinal organs, e.g. for incontinence control
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/36071—Pain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/36082—Cognitive or psychiatric applications, e.g. dementia or Alzheimer's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/372—Arrangements in connection with the implantation of stimulators
    • A61N1/37211—Means for communicating with stimulators
    • A61N1/37235—Aspects of the external programmer

Abstract

A plurality of disorders are treated by neural stimulation with optional neural blocking. These include gastrointestinal disorders as well as neuropsychiatric and cardio-respiratory disorders. The apparatus includes stimulating and blocking electrodes. Stimulating electrodes proving a stimulation signal on a nerve. Blocking electrodes at least partially block nerve impulses at a blocking site.
PCT/US2004/002847 2003-02-03 2004-01-30 Neural stimulation WO2004069331A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
DK04707122.0T DK1601414T3 (en) 2003-02-03 2004-01-30 Neural stimulation
AT04707122T ATE547148T1 (en) 2003-02-03 2004-01-30 NERVE STIMULATION DEVICE
EP04707122A EP1601414B1 (en) 2003-02-03 2004-01-30 Apparatus for neural stimulation

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US10/358,093 2003-02-03
US10/358,093 US20040172084A1 (en) 2003-02-03 2003-02-03 Method and apparatus for treatment of gastro-esophageal reflux disease (GERD)
US10/675,818 2003-09-29
US10/674,330 US7489969B2 (en) 2003-02-03 2003-09-29 Vagal down-regulation obesity treatment
US10/674,324 2003-09-29
US10/674,324 US20040172085A1 (en) 2003-02-03 2003-09-29 Nerve stimulation and conduction block therapy
US10/674,330 2003-09-29
US10/675,818 US20040176812A1 (en) 2003-02-03 2003-09-29 Enteric rhythm management

Publications (3)

Publication Number Publication Date
WO2004069331A2 WO2004069331A2 (en) 2004-08-19
WO2004069331A3 true WO2004069331A3 (en) 2005-01-20
WO2004069331B1 WO2004069331B1 (en) 2005-03-17

Family

ID=32854477

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/002847 WO2004069331A2 (en) 2003-02-03 2004-01-30 Neural stimulation

Country Status (3)

Country Link
US (10) US7167750B2 (en)
EP (1) EP1601414B1 (en)
WO (1) WO2004069331A2 (en)

Families Citing this family (402)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7076307B2 (en) * 2002-05-09 2006-07-11 Boveja Birinder R Method and system for modulating the vagus nerve (10th cranial nerve) with electrical pulses using implanted and external components, to provide therapy neurological and neuropsychiatric disorders
US9101765B2 (en) 1999-03-05 2015-08-11 Metacure Limited Non-immediate effects of therapy
US8666495B2 (en) 1999-03-05 2014-03-04 Metacure Limited Gastrointestinal methods and apparatus for use in treating disorders and controlling blood sugar
US6587719B1 (en) * 1999-07-01 2003-07-01 Cyberonics, Inc. Treatment of obesity by bilateral vagus nerve stimulation
US7300449B2 (en) * 1999-12-09 2007-11-27 Mische Hans A Methods and devices for the treatment of neurological and physiological disorders
US6600953B2 (en) 2000-12-11 2003-07-29 Impulse Dynamics N.V. Acute and chronic electrical signal therapy for obesity
US8914114B2 (en) 2000-05-23 2014-12-16 The Feinstein Institute For Medical Research Inhibition of inflammatory cytokine production by cholinergic agonists and vagus nerve stimulation
AU2001266345B2 (en) * 2000-06-30 2006-03-02 Sumitomo Dainippon Pharma Co., Ltd. Five-membered-ring compound
US6609025B2 (en) * 2001-01-02 2003-08-19 Cyberonics, Inc. Treatment of obesity by bilateral sub-diaphragmatic nerve stimulation
EP1357971B1 (en) * 2001-01-05 2015-05-20 Metacure Limited Regulation of eating habits
US7330753B2 (en) * 2001-04-18 2008-02-12 Metacure N.V. Analysis of eating habits
US7702394B2 (en) 2001-05-01 2010-04-20 Intrapace, Inc. Responsive gastric stimulator
US7616996B2 (en) 2005-09-01 2009-11-10 Intrapace, Inc. Randomized stimulation of a gastrointestinal organ
US20050143784A1 (en) * 2001-05-01 2005-06-30 Imran Mir A. Gastrointestinal anchor with optimal surface area
US7756582B2 (en) * 2001-05-01 2010-07-13 Intrapace, Inc. Gastric stimulation anchor and method
US7747322B2 (en) 2001-05-01 2010-06-29 Intrapace, Inc. Digestive organ retention device
US7689284B2 (en) 2001-05-01 2010-03-30 Intrapace, Inc. Pseudounipolar lead for stimulating a digestive organ
US7979127B2 (en) 2001-05-01 2011-07-12 Intrapace, Inc. Digestive organ retention device
US8774913B2 (en) 2002-04-08 2014-07-08 Medtronic Ardian Luxembourg S.A.R.L. Methods and apparatus for intravasculary-induced neuromodulation
US7617005B2 (en) 2002-04-08 2009-11-10 Ardian, Inc. Methods and apparatus for thermally-induced renal neuromodulation
US8347891B2 (en) 2002-04-08 2013-01-08 Medtronic Ardian Luxembourg S.A.R.L. Methods and apparatus for performing a non-continuous circumferential treatment of a body lumen
US7653438B2 (en) 2002-04-08 2010-01-26 Ardian, Inc. Methods and apparatus for renal neuromodulation
US8145316B2 (en) 2002-04-08 2012-03-27 Ardian, Inc. Methods and apparatus for renal neuromodulation
US9636174B2 (en) 2002-04-08 2017-05-02 Medtronic Ardian Luxembourg S.A.R.L. Methods for therapeutic renal neuromodulation
US7162303B2 (en) 2002-04-08 2007-01-09 Ardian, Inc. Renal nerve stimulation method and apparatus for treatment of patients
US20070129761A1 (en) 2002-04-08 2007-06-07 Ardian, Inc. Methods for treating heart arrhythmia
US8774922B2 (en) 2002-04-08 2014-07-08 Medtronic Ardian Luxembourg S.A.R.L. Catheter apparatuses having expandable balloons for renal neuromodulation and associated systems and methods
US9308044B2 (en) 2002-04-08 2016-04-12 Medtronic Ardian Luxembourg S.A.R.L. Methods for therapeutic renal neuromodulation
US7620451B2 (en) 2005-12-29 2009-11-17 Ardian, Inc. Methods and apparatus for pulsed electric field neuromodulation via an intra-to-extravascular approach
US20140018880A1 (en) 2002-04-08 2014-01-16 Medtronic Ardian Luxembourg S.A.R.L. Methods for monopolar renal neuromodulation
US9308043B2 (en) 2002-04-08 2016-04-12 Medtronic Ardian Luxembourg S.A.R.L. Methods for monopolar renal neuromodulation
US6978174B2 (en) 2002-04-08 2005-12-20 Ardian, Inc. Methods and devices for renal nerve blocking
US20070135875A1 (en) 2002-04-08 2007-06-14 Ardian, Inc. Methods and apparatus for thermally-induced renal neuromodulation
US7853333B2 (en) 2002-04-08 2010-12-14 Ardian, Inc. Methods and apparatus for multi-vessel renal neuromodulation
US8145317B2 (en) 2002-04-08 2012-03-27 Ardian, Inc. Methods for renal neuromodulation
US7756583B2 (en) 2002-04-08 2010-07-13 Ardian, Inc. Methods and apparatus for intravascularly-induced neuromodulation
US8150519B2 (en) 2002-04-08 2012-04-03 Ardian, Inc. Methods and apparatus for bilateral renal neuromodulation
US20080213331A1 (en) 2002-04-08 2008-09-04 Ardian, Inc. Methods and devices for renal nerve blocking
US8175711B2 (en) 2002-04-08 2012-05-08 Ardian, Inc. Methods for treating a condition or disease associated with cardio-renal function
US8131371B2 (en) 2002-04-08 2012-03-06 Ardian, Inc. Methods and apparatus for monopolar renal neuromodulation
US7837719B2 (en) 2002-05-09 2010-11-23 Daemen College Electrical stimulation unit and waterbath system
US20040082859A1 (en) 2002-07-01 2004-04-29 Alan Schaer Method and apparatus employing ultrasound energy to treat body sphincters
US7025791B2 (en) 2002-12-02 2006-04-11 Gi Dynamics, Inc. Bariatric sleeve
US7608114B2 (en) 2002-12-02 2009-10-27 Gi Dynamics, Inc. Bariatric sleeve
US7695446B2 (en) 2002-12-02 2010-04-13 Gi Dynamics, Inc. Methods of treatment using a bariatric sleeve
US7678068B2 (en) 2002-12-02 2010-03-16 Gi Dynamics, Inc. Atraumatic delivery devices
EP1569582B1 (en) 2002-12-02 2017-05-31 GI Dynamics, Inc. Bariatric sleeve
US20040172084A1 (en) 2003-02-03 2004-09-02 Knudson Mark B. Method and apparatus for treatment of gastro-esophageal reflux disease (GERD)
US7613515B2 (en) * 2003-02-03 2009-11-03 Enteromedics Inc. High frequency vagal blockage therapy
US7844338B2 (en) * 2003-02-03 2010-11-30 Enteromedics Inc. High frequency obesity treatment
US7167750B2 (en) 2003-02-03 2007-01-23 Enteromedics, Inc. Obesity treatment with electrically induced vagal down regulation
US7684865B2 (en) * 2003-03-14 2010-03-23 Endovx, Inc. Methods and apparatus for treatment of obesity
US8792985B2 (en) 2003-07-21 2014-07-29 Metacure Limited Gastrointestinal methods and apparatus for use in treating disorders and controlling blood sugar
US8821521B2 (en) * 2003-07-28 2014-09-02 Baronova, Inc. Gastro-intestinal device and method for treating addiction
US9700450B2 (en) 2003-07-28 2017-07-11 Baronova, Inc. Devices and methods for gastrointestinal stimulation
US9498366B2 (en) * 2003-07-28 2016-11-22 Baronova, Inc. Devices and methods for pyloric anchoring
US8048169B2 (en) * 2003-07-28 2011-11-01 Baronova, Inc. Pyloric valve obstructing devices and methods
US20090259236A2 (en) * 2003-07-28 2009-10-15 Baronova, Inc. Gastric retaining devices and methods
AU2004266574B2 (en) * 2003-08-13 2010-11-04 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Compressive device for percutaneous treatment of obesity
US20050070970A1 (en) * 2003-09-29 2005-03-31 Knudson Mark B. Movement disorder stimulation with neural block
US7054690B2 (en) * 2003-10-22 2006-05-30 Intrapace, Inc. Gastrointestinal stimulation device
US9050469B1 (en) 2003-11-26 2015-06-09 Flint Hills Scientific, Llc Method and system for logging quantitative seizure information and assessing efficacy of therapy using cardiac signals
US8057420B2 (en) 2003-12-09 2011-11-15 Gi Dynamics, Inc. Gastrointestinal implant with drawstring
EP1708655A1 (en) 2003-12-09 2006-10-11 GI Dynamics, Inc. Apparatus to be anchored within the gastrointestinal tract and anchoring method
US20060142790A1 (en) * 2004-03-23 2006-06-29 Michael Gertner Methods and devices to facilitate connections between body lumens
US20060195139A1 (en) * 2004-03-23 2006-08-31 Michael Gertner Extragastric devices and methods for gastroplasty
WO2007067206A2 (en) * 2005-05-10 2007-06-14 Michael Gertner Obesity treatment systems
US20070233170A1 (en) * 2004-03-23 2007-10-04 Michael Gertner Extragastric Balloon
WO2006049725A2 (en) * 2004-03-23 2006-05-11 Minimus Surgical Systems Surgical systems and devices to enhance gastric restriction therapies
US7946976B2 (en) * 2004-03-23 2011-05-24 Michael Gertner Methods and devices for the surgical creation of satiety and biofeedback pathways
US7255675B2 (en) * 2004-03-23 2007-08-14 Michael Gertner Devices and methods to treat a patient
EP1734941A2 (en) * 2004-03-25 2006-12-27 The Feinstein Institute for Medical Research Neural tourniquet
US10912712B2 (en) 2004-03-25 2021-02-09 The Feinstein Institutes For Medical Research Treatment of bleeding by non-invasive stimulation
EP1740132B1 (en) * 2004-04-26 2014-12-31 Synecor, LLC Restrictive and/or obstructive implant for inducing weight loss
US7803195B2 (en) * 2004-06-03 2010-09-28 Mayo Foundation For Medical Education And Research Obesity treatment and device
WO2006002375A2 (en) * 2004-06-23 2006-01-05 The Feinstein Institute For Medical Research Method of treating ileus by pharmacological activation of cholinergic receptors
US7664551B2 (en) * 2004-07-07 2010-02-16 Medtronic Transneuronix, Inc. Treatment of the autonomic nervous system
US7837643B2 (en) 2004-07-09 2010-11-23 Gi Dynamics, Inc. Methods and devices for placing a gastrointestinal sleeve
US20060020277A1 (en) * 2004-07-20 2006-01-26 Gostout Christopher J Gastric reshaping devices and methods
US20060020298A1 (en) * 2004-07-20 2006-01-26 Camilleri Michael L Systems and methods for curbing appetite
US8612016B2 (en) 2004-08-18 2013-12-17 Metacure Limited Monitoring, analysis, and regulation of eating habits
AU2005287010B2 (en) 2004-09-17 2010-04-15 Gi Dynamics, Inc. Gastrointestinal anchor
US20060070334A1 (en) * 2004-09-27 2006-04-06 Blue Hen, Llc Sidewall plank for constructing a trailer and associated trailer sidewall construction
ES2582334T3 (en) 2004-10-15 2016-09-12 Bfkw, Llc Bariatric device
US7833279B2 (en) * 2004-11-12 2010-11-16 Enteromedics Inc. Pancreatic exocrine secretion diversion apparatus and method
CN101124012B (en) 2004-12-27 2012-09-05 范因斯坦医学研究院 Device for treating inflammatory disorders by electrical vagus nerve stimulation
US11207518B2 (en) * 2004-12-27 2021-12-28 The Feinstein Institutes For Medical Research Treating inflammatory disorders by stimulation of the cholinergic anti-inflammatory pathway
US8600521B2 (en) 2005-01-27 2013-12-03 Cyberonics, Inc. Implantable medical device having multiple electrode/sensor capability and stimulation based on sensed intrinsic activity
US7561918B2 (en) * 2005-01-28 2009-07-14 Cyberonics, Inc. Autocapture in a neurostimulator
US7454245B2 (en) * 2005-01-28 2008-11-18 Cyberonics, Inc. Trained and adaptive response in a neurostimulator
US9314633B2 (en) 2008-01-25 2016-04-19 Cyberonics, Inc. Contingent cardio-protection for epilepsy patients
US8565867B2 (en) 2005-01-28 2013-10-22 Cyberonics, Inc. Changeable electrode polarity stimulation by an implantable medical device
US8260426B2 (en) 2008-01-25 2012-09-04 Cyberonics, Inc. Method, apparatus and system for bipolar charge utilization during stimulation by an implantable medical device
US9821158B2 (en) 2005-02-17 2017-11-21 Metacure Limited Non-immediate effects of therapy
US8700163B2 (en) * 2005-03-04 2014-04-15 Cyberonics, Inc. Cranial nerve stimulation for treatment of substance addiction
WO2007080595A2 (en) 2006-01-12 2007-07-19 Metacure N.V. Electrode assemblies, tools, and methods for gastric wall implantation
WO2006129321A2 (en) 2005-06-02 2006-12-07 Metacure N.V. Gi lead implantation
US7899540B2 (en) * 2005-04-29 2011-03-01 Cyberonics, Inc. Noninvasively adjustable gastric band
US7835796B2 (en) * 2005-04-29 2010-11-16 Cyberonics, Inc. Weight loss method and device
US7310557B2 (en) * 2005-04-29 2007-12-18 Maschino Steven E Identification of electrodes for nerve stimulation in the treatment of eating disorders
US7976488B2 (en) 2005-06-08 2011-07-12 Gi Dynamics, Inc. Gastrointestinal anchor compliance
US20070016262A1 (en) 2005-07-13 2007-01-18 Betastim, Ltd. Gi and pancreatic device for treating obesity and diabetes
US7711419B2 (en) * 2005-07-13 2010-05-04 Cyberonics, Inc. Neurostimulator with reduced size
US8862243B2 (en) 2005-07-25 2014-10-14 Rainbow Medical Ltd. Electrical stimulation of blood vessels
US7840280B2 (en) 2005-07-27 2010-11-23 Cyberonics, Inc. Cranial nerve stimulation to treat a vocal cord disorder
US20070027504A1 (en) * 2005-07-27 2007-02-01 Cyberonics, Inc. Cranial nerve stimulation to treat a hearing disorder
US20070027484A1 (en) * 2005-07-28 2007-02-01 Cyberonics, Inc. Autonomic nerve stimulation to treat a pancreatic disorder
US7856273B2 (en) * 2005-07-28 2010-12-21 Cyberonics, Inc. Autonomic nerve stimulation to treat a gastrointestinal disorder
US7672727B2 (en) 2005-08-17 2010-03-02 Enteromedics Inc. Neural electrode treatment
US7822486B2 (en) * 2005-08-17 2010-10-26 Enteromedics Inc. Custom sized neural electrodes
US20070073354A1 (en) 2005-09-26 2007-03-29 Knudson Mark B Neural blocking therapy
US8442841B2 (en) 2005-10-20 2013-05-14 Matacure N.V. Patient selection method for assisting weight loss
US20070092591A1 (en) * 2005-10-24 2007-04-26 Cyberonics, Inc. Vacuum mandrel for use in fabricating an implantable electrode
US8509914B2 (en) * 2005-10-28 2013-08-13 Cyberonics, Inc. Insert for implantable electrode
US7957796B2 (en) 2005-10-28 2011-06-07 Cyberonics, Inc. Using physiological sensor data with an implantable medical device
US8041428B2 (en) 2006-02-10 2011-10-18 Electrocore Llc Electrical stimulation treatment of hypotension
US20090234417A1 (en) * 2005-11-10 2009-09-17 Electrocore, Inc. Methods And Apparatus For The Treatment Of Metabolic Disorders
US8295932B2 (en) 2005-12-05 2012-10-23 Metacure Limited Ingestible capsule for appetite regulation
CN103214484B (en) 2005-12-13 2016-07-06 因塞特控股公司 Pyrrolo-[2,3-b] pyridine replaced as the heteroaryl of Janus inhibitors of kinases and pyrrolo-[2,3-b] pyrimidine
US7996079B2 (en) 2006-01-24 2011-08-09 Cyberonics, Inc. Input response override for an implantable medical device
US7657310B2 (en) * 2006-01-26 2010-02-02 Cyberonics, Inc. Treatment of reproductive endocrine disorders by vagus nerve stimulation
US7467016B2 (en) * 2006-01-27 2008-12-16 Cyberonics, Inc. Multipolar stimulation electrode with mating structures for gripping targeted tissue
US7801601B2 (en) 2006-01-27 2010-09-21 Cyberonics, Inc. Controlling neuromodulation using stimulus modalities
EP1981584B1 (en) 2006-02-03 2015-05-13 Interventional Autonomics Corporation Intravascular device for neuromodulation
EP1984065B1 (en) * 2006-02-10 2012-08-22 Electrocore, Inc. Electrical stimulation treatment of hypotension
US8027718B2 (en) * 2006-03-07 2011-09-27 Mayo Foundation For Medical Education And Research Regional anesthetic
ES2538726T3 (en) 2006-03-29 2015-06-23 Dignity Health Vagus nerve stimulation system
US8180462B2 (en) 2006-04-18 2012-05-15 Cyberonics, Inc. Heat dissipation for a lead assembly
US8209034B2 (en) * 2008-12-18 2012-06-26 Electrocore Llc Methods and apparatus for electrical stimulation treatment using esophageal balloon and electrode
US20100057178A1 (en) * 2006-04-18 2010-03-04 Electrocore, Inc. Methods and apparatus for spinal cord stimulation using expandable electrode
US8401650B2 (en) 2008-04-10 2013-03-19 Electrocore Llc Methods and apparatus for electrical treatment using balloon and electrode
US20080183237A1 (en) * 2006-04-18 2008-07-31 Electrocore, Inc. Methods And Apparatus For Treating Ileus Condition Using Electrical Signals
US8187297B2 (en) 2006-04-19 2012-05-29 Vibsynt, Inc. Devices and methods for treatment of obesity
US8342183B2 (en) 2006-04-19 2013-01-01 Vibrynt, Inc. Devices and methods for treatment of obesity
US20090281498A1 (en) * 2006-04-19 2009-11-12 Acosta Pablo G Devices, system and methods for minimally invasive abdominal surgical procedures
US8585733B2 (en) * 2006-04-19 2013-11-19 Vibrynt, Inc Devices, tools and methods for performing minimally invasive abdominal surgical procedures
US20090272388A1 (en) * 2006-04-19 2009-11-05 Shuji Uemura Minimally-invasive methods for implanting obesity treatment devices
US20090281386A1 (en) * 2006-04-19 2009-11-12 Acosta Pablo G Devices, system and methods for minimally invasive abdominal surgical procedures
US20090281376A1 (en) * 2006-04-19 2009-11-12 Acosta Pablo G Devices, system and methods for minimally invasive abdominal surgical procedures
US8070768B2 (en) 2006-04-19 2011-12-06 Vibrynt, Inc. Devices and methods for treatment of obesity
US20110172767A1 (en) * 2006-04-19 2011-07-14 Pankaj Rathi Minimally invasive, direct delivery methods for implanting obesity treatment devices
US7976554B2 (en) * 2006-04-19 2011-07-12 Vibrynt, Inc. Devices, tools and methods for performing minimally invasive abdominal surgical procedures
US20090287227A1 (en) * 2006-04-19 2009-11-19 Newell Matthew B Minimally invasive ,methods for implanting obesity treatment devices
US8556925B2 (en) 2007-10-11 2013-10-15 Vibrynt, Inc. Devices and methods for treatment of obesity
US20090275972A1 (en) * 2006-04-19 2009-11-05 Shuji Uemura Minimally-invasive methods for implanting obesity treatment devices
US8398668B2 (en) 2006-04-19 2013-03-19 Vibrynt, Inc. Devices and methods for treatment of obesity
US7869885B2 (en) * 2006-04-28 2011-01-11 Cyberonics, Inc Threshold optimization for tissue stimulation therapy
US20070255336A1 (en) * 2006-04-28 2007-11-01 Medtronic, Inc. Gastric constriction device with selectable electrode combinations
US7962220B2 (en) 2006-04-28 2011-06-14 Cyberonics, Inc. Compensation reduction in tissue stimulation therapy
US20070255335A1 (en) * 2006-04-28 2007-11-01 Medtronic, Inc. Controller for gastric constriction device with selectable electrode configurations
US9020597B2 (en) 2008-11-12 2015-04-28 Endostim, Inc. Device and implantation system for electrical stimulation of biological systems
US7734341B2 (en) * 2006-06-06 2010-06-08 Cardiac Pacemakers, Inc. Method and apparatus for gastrointestinal stimulation via the lymphatic system
US20070282376A1 (en) 2006-06-06 2007-12-06 Shuros Allan C Method and apparatus for neural stimulation via the lymphatic system
US8478420B2 (en) 2006-07-12 2013-07-02 Cyberonics, Inc. Implantable medical device charge balance assessment
US20080027524A1 (en) 2006-07-26 2008-01-31 Maschino Steven E Multi-electrode assembly for an implantable medical device
US8905999B2 (en) 2006-09-01 2014-12-09 Cardiac Pacemakers, Inc. Method and apparatus for endolymphatic drug delivery
US20080071173A1 (en) * 2006-09-18 2008-03-20 Aldrich William N Visualizing Formation of Ablation Lesions
JP4314259B2 (en) * 2006-09-29 2009-08-12 株式会社東芝 Nonvolatile semiconductor memory
US20080086180A1 (en) * 2006-10-05 2008-04-10 Omry Ben-Ezra Techniques for gall bladder stimulation
US7738961B2 (en) * 2006-10-09 2010-06-15 Endostim, Inc. Method and apparatus for treatment of the gastrointestinal tract
US9345879B2 (en) * 2006-10-09 2016-05-24 Endostim, Inc. Device and implantation system for electrical stimulation of biological systems
US20150224310A1 (en) * 2006-10-09 2015-08-13 Endostim, Inc. Device and Implantation System for Electrical Stimulation of Biological Systems
US9724510B2 (en) * 2006-10-09 2017-08-08 Endostim, Inc. System and methods for electrical stimulation of biological systems
US11577077B2 (en) 2006-10-09 2023-02-14 Endostim, Inc. Systems and methods for electrical stimulation of biological systems
US7869867B2 (en) 2006-10-27 2011-01-11 Cyberonics, Inc. Implantable neurostimulator with refractory stimulation
WO2008058028A2 (en) * 2006-11-03 2008-05-15 Gep Technology, Inc. Apparatus and methods for minimally invasive obesity treatment
EP2066272A2 (en) * 2006-12-28 2009-06-10 Vibrynt, Inc. Devices and methods for treatment of obesity
CL2008000070A1 (en) * 2007-01-17 2008-07-25 Lg Life Sciences Ltd MALEIC ACID MONOSAL (3 - [({1 - [(2-AMINO-9H-PURIN-9-IL) METHYL] CICLOPROPIL} OXI) METHYL] -8,8-DIMETHYL-3,7-DIOXO-2,4 , 6-TRIOXA-3 LAMBDA 5-PHOSPHANON-1-IL-PIVALATE; PHARMACEUTICAL COMPOSITION THAT INCLUDES THE SUCH MONOSAL; AND USE FOR THE TREATMENT OF VIRUS H
US8301239B2 (en) * 2007-01-18 2012-10-30 Cardiac Pacemakers, Inc. Systems, devices and methods for acute autonomic stimulation
US7706875B2 (en) * 2007-01-25 2010-04-27 Cyberonics, Inc. Modulation of drug effects by vagus nerve stimulation
US7974707B2 (en) 2007-01-26 2011-07-05 Cyberonics, Inc. Electrode assembly with fibers for a medical device
US20080183186A1 (en) * 2007-01-30 2008-07-31 Cardiac Pacemakers, Inc. Method and apparatus for delivering a transvascular lead
US7917230B2 (en) * 2007-01-30 2011-03-29 Cardiac Pacemakers, Inc. Neurostimulating lead having a stent-like anchor
US8244378B2 (en) * 2007-01-30 2012-08-14 Cardiac Pacemakers, Inc. Spiral configurations for intravascular lead stability
US20080183265A1 (en) * 2007-01-30 2008-07-31 Cardiac Pacemakers, Inc. Transvascular lead with proximal force relief
US20080183264A1 (en) * 2007-01-30 2008-07-31 Cardiac Pacemakers, Inc. Electrode configurations for transvascular nerve stimulation
US20080183255A1 (en) * 2007-01-30 2008-07-31 Cardiac Pacemakers, Inc. Side port lead delivery system
US7949409B2 (en) * 2007-01-30 2011-05-24 Cardiac Pacemakers, Inc. Dual spiral lead configurations
US20080183187A1 (en) * 2007-01-30 2008-07-31 Cardiac Pacemakers, Inc. Direct delivery system for transvascular lead
US8755896B2 (en) * 2007-02-05 2014-06-17 University Of Southern California Treatment of consumption disorders with biostimulation
AU2008216316A1 (en) * 2007-02-13 2008-08-21 Virender K. Sharma Method and apparatus for electrical stimulation of the pancreatico-biliary system
US8529431B2 (en) * 2007-02-14 2013-09-10 Bfkw, Llc Bariatric device and method
US8801647B2 (en) 2007-02-22 2014-08-12 Gi Dynamics, Inc. Use of a gastrointestinal sleeve to treat bariatric surgery fistulas and leaks
US8068918B2 (en) * 2007-03-09 2011-11-29 Enteromedics Inc. Remote monitoring and control of implantable devices
CA2680477A1 (en) * 2007-03-13 2008-09-18 The Feinstein Institute For Medical Research Treatment of inflammation by non-invasive stimulation
US7962214B2 (en) 2007-04-26 2011-06-14 Cyberonics, Inc. Non-surgical device and methods for trans-esophageal vagus nerve stimulation
US7869884B2 (en) 2007-04-26 2011-01-11 Cyberonics, Inc. Non-surgical device and methods for trans-esophageal vagus nerve stimulation
US7904175B2 (en) 2007-04-26 2011-03-08 Cyberonics, Inc. Trans-esophageal vagus nerve stimulation
US7974701B2 (en) 2007-04-27 2011-07-05 Cyberonics, Inc. Dosing limitation for an implantable medical device
US8417329B2 (en) * 2007-05-09 2013-04-09 Metacure Ltd. Analysis and regulation of food intake
US20080281365A1 (en) * 2007-05-09 2008-11-13 Tweden Katherine S Neural signal duty cycle
US20080300657A1 (en) * 2007-05-31 2008-12-04 Mark Raymond Stultz Therapy system
WO2008157208A2 (en) * 2007-06-13 2008-12-24 Incyte Corporation Salts of the janus kinase inhibitor (r)-3-(4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1h-pyrazol-1-yl)-3-cyclopentylpropanenitrile
WO2009013749A2 (en) 2007-07-24 2009-01-29 Betastim, Ltd. Duodenal eating sensor
US7818069B2 (en) * 2007-07-27 2010-10-19 Cyberonics, Inc. Ribbon electrode
EP2195081A1 (en) * 2007-08-20 2010-06-16 Medtronic, INC. Electrode configurations for directional leads
EP2195078B1 (en) 2007-08-20 2013-10-09 Medtronic, Inc. Implantable medical lead with biased electrode
WO2009025817A2 (en) 2007-08-20 2009-02-26 Medtronic, Inc. Evaluating therapeutic stimulation electrode configurations based on physiological responses
WO2009029614A1 (en) 2007-08-27 2009-03-05 The Feinstein Institute For Medical Research Devices and methods for inhibiting granulocyte activation by neural stimulation
WO2009033049A1 (en) * 2007-09-07 2009-03-12 Baronova, Inc. Device for intermittently obstructing a gastric opening and method of use
WO2009038802A1 (en) * 2007-09-20 2009-03-26 Theodore Khalili Sensor and pacemaker imbedded with a gastric banding
US20090248033A1 (en) 2007-10-11 2009-10-01 Milux Holding S.A. Method for the treatment of gallstones
EP2211771B1 (en) * 2007-10-11 2021-01-13 Implantica Patent Ltd. Apparatus for the treatment of gallstones
US8868203B2 (en) 2007-10-26 2014-10-21 Cyberonics, Inc. Dynamic lead condition detection for an implantable medical device
US8942798B2 (en) 2007-10-26 2015-01-27 Cyberonics, Inc. Alternative operation mode for an implantable medical device based upon lead condition
US20090204173A1 (en) 2007-11-05 2009-08-13 Zi-Ping Fang Multi-Frequency Neural Treatments and Associated Systems and Methods
US8989858B2 (en) * 2007-12-05 2015-03-24 The Invention Science Fund I, Llc Implant system for chemical modulation of neural activity
US20090149799A1 (en) * 2007-12-05 2009-06-11 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Method for chemical modulation of neural activity
US8165668B2 (en) * 2007-12-05 2012-04-24 The Invention Science Fund I, Llc Method for magnetic modulation of neural conduction
US8170660B2 (en) * 2007-12-05 2012-05-01 The Invention Science Fund I, Llc System for thermal modulation of neural activity
UY31531A1 (en) * 2007-12-17 2009-08-03 SALTS DERIVED FROM 8-OXOADENINE PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM AND THEIR USE IN THERAPY AS TOLL TYPE RECEIVER MODULATORS (TLR)
US8382667B2 (en) 2010-10-01 2013-02-26 Flint Hills Scientific, Llc Detecting, quantifying, and/or classifying seizures using multimodal data
US8337404B2 (en) 2010-10-01 2012-12-25 Flint Hills Scientific, Llc Detecting, quantifying, and/or classifying seizures using multimodal data
US8571643B2 (en) 2010-09-16 2013-10-29 Flint Hills Scientific, Llc Detecting or validating a detection of a state change from a template of heart rate derivative shape or heart beat wave complex
WO2009094609A1 (en) 2008-01-25 2009-07-30 Sharma Virender K Device and implantation system for electrical stimulation of biological systems
US8565885B2 (en) * 2008-01-30 2013-10-22 The Board Of Regents Of The University Of Texas System Ileal electrical stimulation
US9005106B2 (en) 2008-01-31 2015-04-14 Enopace Biomedical Ltd Intra-aortic electrical counterpulsation
US8538535B2 (en) 2010-08-05 2013-09-17 Rainbow Medical Ltd. Enhancing perfusion by contraction
US9186502B2 (en) * 2008-02-14 2015-11-17 Enteromedics Inc. Treatment of excess weight by neural downregulation in combination with compositions
US7925352B2 (en) 2008-03-27 2011-04-12 Synecor Llc System and method for transvascularly stimulating contents of the carotid sheath
US9662490B2 (en) 2008-03-31 2017-05-30 The Feinstein Institute For Medical Research Methods and systems for reducing inflammation by neuromodulation and administration of an anti-inflammatory drug
WO2009146030A1 (en) 2008-03-31 2009-12-03 The Feinstein Institute For Medical Research Methods and systems for reducing inflammation by neuromodulation of t-cell activity
AU2009231601B2 (en) 2008-04-04 2014-02-27 Reshape Lifesciences, Inc. Methods and systems for glucose regulation
US8682449B2 (en) 2008-04-10 2014-03-25 ElectroCore, LLC Methods and apparatus for transcranial stimulation
US8204603B2 (en) * 2008-04-25 2012-06-19 Cyberonics, Inc. Blocking exogenous action potentials by an implantable medical device
US20090275997A1 (en) * 2008-05-01 2009-11-05 Michael Allen Faltys Vagus nerve stimulation electrodes and methods of use
US7890182B2 (en) 2008-05-15 2011-02-15 Boston Scientific Neuromodulation Corporation Current steering for an implantable stimulator device involving fractionalized stimulation pulses
WO2010006341A1 (en) 2008-07-11 2010-01-14 Gep Technology, Inc. Apparatus and methods for minimally invasive obesity treatment
US8768469B2 (en) 2008-08-08 2014-07-01 Enteromedics Inc. Systems for regulation of blood pressure and heart rate
US10603489B2 (en) 2008-10-09 2020-03-31 Virender K. Sharma Methods and apparatuses for stimulating blood vessels in order to control, treat, and/or prevent a hemorrhage
US9079028B2 (en) 2008-10-09 2015-07-14 Virender K. Sharma Method and apparatus for stimulating the vascular system
US8457747B2 (en) 2008-10-20 2013-06-04 Cyberonics, Inc. Neurostimulation with signal duration determined by a cardiac cycle
US8417344B2 (en) 2008-10-24 2013-04-09 Cyberonics, Inc. Dynamic cranial nerve stimulation based on brain state determination from cardiac data
US8255057B2 (en) 2009-01-29 2012-08-28 Nevro Corporation Systems and methods for producing asynchronous neural responses to treat pain and/or other patient conditions
US9327121B2 (en) 2011-09-08 2016-05-03 Nevro Corporation Selective high frequency spinal cord modulation for inhibiting pain, including cephalic and/or total body pain with reduced side effects, and associated systems and methods
AU2009316801C1 (en) 2008-11-18 2015-12-24 Setpoint Medical Corporation Devices and methods for optimizing electrode placement for anti-inflammatory stimulation
WO2010068797A1 (en) * 2008-12-10 2010-06-17 Waverx, Inc. Devices, systems and methods for preventing and treating sensation loss
US20100160995A1 (en) * 2008-12-18 2010-06-24 Jerome Dargent Method for treating obesity
CA2783009A1 (en) 2008-12-27 2010-07-01 John Hancock High specific gravity intragastric device
US8652129B2 (en) 2008-12-31 2014-02-18 Medtronic Ardian Luxembourg S.A.R.L. Apparatus, systems, and methods for achieving intravascular, thermally-induced renal neuromodulation
US8974445B2 (en) 2009-01-09 2015-03-10 Recor Medical, Inc. Methods and apparatus for treatment of cardiac valve insufficiency
US20100191304A1 (en) 2009-01-23 2010-07-29 Scott Timothy L Implantable Medical Device for Providing Chronic Condition Therapy and Acute Condition Therapy Using Vagus Nerve Stimulation
US20100191265A1 (en) * 2009-01-29 2010-07-29 Cavu Medical, Inc. Assembly and method for automatically controlling pressure for a gastric band
US20100191271A1 (en) * 2009-01-29 2010-07-29 Lilip Lau Assembly and method for automatically controlling pressure for a gastric band
EP2401031B1 (en) * 2009-02-06 2015-07-01 Cardiac Pacemakers, Inc. Cross-channel noise detector in implantable devices
US8326426B2 (en) * 2009-04-03 2012-12-04 Enteromedics, Inc. Implantable device with heat storage
US20110087076A1 (en) 2009-04-03 2011-04-14 Intrapace, Inc. Feedback systems and methods for communicating diagnostic and/or treatment signals to enhance obesity treatments
ES2624748T3 (en) 2009-04-22 2017-07-17 Nevro Corporation Selective high frequency modulation of the spinal cord for pain inhibition with reduced side effects, and associated systems and methods
EP2756864B1 (en) 2009-04-22 2023-03-15 Nevro Corporation Spinal cord modulation systems for inducing paresthetic and anesthetic effects
US8239028B2 (en) * 2009-04-24 2012-08-07 Cyberonics, Inc. Use of cardiac parameters in methods and systems for treating a chronic medical condition
US8827912B2 (en) 2009-04-24 2014-09-09 Cyberonics, Inc. Methods and systems for detecting epileptic events using NNXX, optionally with nonlinear analysis parameters
US9211410B2 (en) 2009-05-01 2015-12-15 Setpoint Medical Corporation Extremely low duty-cycle activation of the cholinergic anti-inflammatory pathway to treat chronic inflammation
US8996116B2 (en) 2009-10-30 2015-03-31 Setpoint Medical Corporation Modulation of the cholinergic anti-inflammatory pathway to treat pain or addiction
US8591396B2 (en) * 2009-05-04 2013-11-26 Covidien Lp Magnetic gastric reduction device
US8414559B2 (en) 2009-05-07 2013-04-09 Rainbow Medical Ltd. Gastroretentive duodenal pill
PE20120371A1 (en) 2009-05-22 2012-05-17 Incyte Corp 3- [4- (7H-PYRROLO [2,3-D] PYRIMIDIN-4YL) -1H-PYRAZOL-1-IL] OCTANE OR HEPTAN-NITRILE AS JAK INHIBITORS
AU2010258792B2 (en) 2009-06-09 2015-07-02 Setpoint Medical Corporation Nerve cuff with pocket for leadless stimulator
US8954166B2 (en) * 2009-06-21 2015-02-10 Eugene Eustis Pettinelli Induced modulation of neuronal transmission
US8498710B2 (en) 2009-07-28 2013-07-30 Nevro Corporation Linked area parameter adjustment for spinal cord stimulation and associated systems and methods
WO2011028685A1 (en) * 2009-09-01 2011-03-10 Incyte Corporation Heterocyclic derivatives of pyrazol-4-yl-pyrrolo[2,3-d]pyrimidines as janus kinase inhibitors
US11051744B2 (en) 2009-11-17 2021-07-06 Setpoint Medical Corporation Closed-loop vagus nerve stimulation
US9833621B2 (en) 2011-09-23 2017-12-05 Setpoint Medical Corporation Modulation of sirtuins by vagus nerve stimulation
US8321012B2 (en) 2009-12-22 2012-11-27 The Invention Science Fund I, Llc Device, method, and system for neural modulation as vaccine adjuvant in a vertebrate subject
CN105126248B (en) 2009-12-23 2018-06-12 赛博恩特医疗器械公司 For treating the nerve stimulation apparatus of chronic inflammation and system
US8934975B2 (en) 2010-02-01 2015-01-13 Metacure Limited Gastrointestinal electrical therapy
US8447403B2 (en) 2010-03-05 2013-05-21 Endostim, Inc. Device and implantation system for electrical stimulation of biological systems
US11717681B2 (en) 2010-03-05 2023-08-08 Endostim, Inc. Systems and methods for treating gastroesophageal reflux disease
MX364636B (en) 2010-03-10 2019-05-03 Incyte Corp Piperidin-4-yl azetidine derivatives as jak1 inhibitors.
US8478428B2 (en) 2010-04-23 2013-07-02 Cyberonics, Inc. Helical electrode for nerve stimulation
US8831732B2 (en) 2010-04-29 2014-09-09 Cyberonics, Inc. Method, apparatus and system for validating and quantifying cardiac beat data quality
US8562536B2 (en) 2010-04-29 2013-10-22 Flint Hills Scientific, Llc Algorithm for detecting a seizure from cardiac data
US8649871B2 (en) 2010-04-29 2014-02-11 Cyberonics, Inc. Validity test adaptive constraint modification for cardiac data used for detection of state changes
KR102040479B1 (en) 2010-05-21 2019-11-06 인사이트 홀딩스 코포레이션 Topical formulation for a jak inhibitor
US8825164B2 (en) 2010-06-11 2014-09-02 Enteromedics Inc. Neural modulation devices and methods
US10420665B2 (en) 2010-06-13 2019-09-24 W. L. Gore & Associates, Inc. Intragastric device for treating obesity
US8628554B2 (en) 2010-06-13 2014-01-14 Virender K. Sharma Intragastric device for treating obesity
US9526648B2 (en) 2010-06-13 2016-12-27 Synerz Medical, Inc. Intragastric device for treating obesity
US10010439B2 (en) 2010-06-13 2018-07-03 Synerz Medical, Inc. Intragastric device for treating obesity
US8679009B2 (en) 2010-06-15 2014-03-25 Flint Hills Scientific, Llc Systems approach to comorbidity assessment
US8641646B2 (en) 2010-07-30 2014-02-04 Cyberonics, Inc. Seizure detection using coordinate data
WO2012045030A2 (en) 2010-10-01 2012-04-05 Intrapace, Inc. Feedback systems and methods to enhance obstructive and other obesity treatments, optionally using multiple sensors
US8684921B2 (en) 2010-10-01 2014-04-01 Flint Hills Scientific Llc Detecting, assessing and managing epilepsy using a multi-variate, metric-based classification analysis
CN107007348B (en) 2010-10-25 2019-05-31 美敦力Af卢森堡有限责任公司 For the estimation of nerve modulation treatment and device, the system and method for feedback
SG190839A1 (en) 2010-11-19 2013-07-31 Incyte Corp Cyclobutyl substituted pyrrolopyridine and pyrrolopyrimidine derivatives as jak inhibitors
WO2012068440A1 (en) 2010-11-19 2012-05-24 Incyte Corporation Heterocyclic-substituted pyrrolopyridines and pyrrolopyrimidines as jak inhibitors
AU2011336606B2 (en) 2010-11-30 2016-06-23 Nevro Corporation Extended pain relief via high frequency spinal cord modulation, and associated systems and methods
US9504390B2 (en) 2011-03-04 2016-11-29 Globalfoundries Inc. Detecting, assessing and managing a risk of death in epilepsy
CN103596515A (en) 2011-04-14 2014-02-19 恩多斯提姆公司 Systems and methods for treating gastroesophageal reflux disease
US9498162B2 (en) 2011-04-25 2016-11-22 Cyberonics, Inc. Identifying seizures using heart data from two or more windows
WO2012149167A2 (en) 2011-04-26 2012-11-01 Christopher Gerard Kunis Method and device for treatment of hypertension and other maladies
US9402550B2 (en) 2011-04-29 2016-08-02 Cybertronics, Inc. Dynamic heart rate threshold for neurological event detection
CN103619405B (en) 2011-05-09 2015-11-25 赛博恩特医疗器械公司 The individual pulse being used for the treatment of the cholinergic anti-inflammatory pathway of chronic inflammatory disease activates
US10758723B2 (en) 2011-05-19 2020-09-01 Neuros Medical, Inc. Nerve cuff electrode for neuromodulation in large human nerve trunks
US11413458B2 (en) 2011-05-19 2022-08-16 Neuros Medical, Inc. Nerve cuff electrode for neuromodulation in large human nerve trunks
JP2014516696A (en) 2011-05-19 2014-07-17 ニューロス・メディカル・インコーポレイティッド High frequency electric nerve block
US9295841B2 (en) 2011-05-19 2016-03-29 Meuros Medical, Inc. High-frequency electrical nerve block
BR112013032720A2 (en) 2011-06-20 2016-09-13 Incyte Corp "azetidinyl phenyl, pyridyl or pyrazinyl carboxamide derivatives as jak inhibitors, composition and use of said derivatives"
CA2842001C (en) * 2011-06-27 2019-06-04 Michael Gabriel Tal Esophageal stimulation devices and methods
US9999767B2 (en) 2011-06-27 2018-06-19 E-Motion Medical, Ltd. Esophageal stimulation system
CN102952138B (en) * 2011-08-17 2016-07-06 上海特化医药科技有限公司 The salt of a kind of pyrazolopyrimidinone compound, polymorph and pharmaceutical composition, preparation method and application
TW201313721A (en) 2011-08-18 2013-04-01 Incyte Corp Cyclohexyl azetidine derivatives as JAK inhibitors
US9925367B2 (en) 2011-09-02 2018-03-27 Endostim, Inc. Laparoscopic lead implantation method
US9037245B2 (en) 2011-09-02 2015-05-19 Endostim, Inc. Endoscopic lead implantation method
UA111854C2 (en) 2011-09-07 2016-06-24 Інсайт Холдінгс Корпорейшн METHODS AND INTERMEDIATE COMPOUNDS FOR JAK INHIBITORS
WO2013035092A2 (en) 2011-09-09 2013-03-14 Enopace Biomedical Ltd. Wireless endovascular stent-based electrodes
US9549677B2 (en) 2011-10-14 2017-01-24 Flint Hills Scientific, L.L.C. Seizure detection methods, apparatus, and systems using a wavelet transform maximum modulus algorithm
US20140330068A1 (en) * 2011-12-02 2014-11-06 Michael J. Partsch Method for modulating the enteric nervous system to treat a disorder
US8382775B1 (en) 2012-01-08 2013-02-26 Vibrynt, Inc. Methods, instruments and devices for extragastric reduction of stomach volume
US9314362B2 (en) 2012-01-08 2016-04-19 Vibrynt, Inc. Methods, instruments and devices for extragastric reduction of stomach volume
US9782583B2 (en) 2012-02-21 2017-10-10 Virender K. Sharma System and method for electrical stimulation of anorectal structures to treat urinary dysfunction
US10576278B2 (en) 2012-02-21 2020-03-03 Virender K. Sharma System and method for electrical stimulation of anorectal structures to treat urinary dysfunction
US8706234B2 (en) 2012-02-21 2014-04-22 Virender K. Sharma System and method for electrical stimulation of anorectal structures to treat anal dysfunction
RU2644933C2 (en) 2012-03-08 2018-02-14 Медтроник Аф Люксембург Сарл Biomarker samples selection as part of devices for neuromodulation and relevant systems and methods
AU2013230781B2 (en) 2012-03-08 2015-12-03 Medtronic Af Luxembourg S.A.R.L. Ovarian neuromodulation and associated systems and methods
US9572983B2 (en) 2012-03-26 2017-02-21 Setpoint Medical Corporation Devices and methods for modulation of bone erosion
WO2013143600A1 (en) * 2012-03-30 2013-10-03 Ethicon Endo-Surgery, Inc. Devices and methods for the treatment of metabolic disorders.
WO2013143599A1 (en) * 2012-03-30 2013-10-03 Ethicon Endo-Surgery, Inc. Devices and methods for the treatment of metabolic disorders.
US8676331B2 (en) 2012-04-02 2014-03-18 Nevro Corporation Devices for controlling spinal cord modulation for inhibiting pain, and associated systems and methods, including controllers for automated parameter selection
US10448839B2 (en) 2012-04-23 2019-10-22 Livanova Usa, Inc. Methods, systems and apparatuses for detecting increased risk of sudden death
WO2013173720A1 (en) 2012-05-18 2013-11-21 Incyte Corporation Piperidinylcyclobutyl substituted pyrrolopyridine and pyrrolopyrimidine derivatives as jak inhibitors
US9456916B2 (en) 2013-03-12 2016-10-04 Medibotics Llc Device for selectively reducing absorption of unhealthy food
US9833614B1 (en) 2012-06-22 2017-12-05 Nevro Corp. Autonomic nervous system control via high frequency spinal cord modulation, and associated systems and methods
EP2888000A4 (en) 2012-08-23 2016-07-06 Endostim Inc Device and implantation system for electrical stimulation of biological systems
US20140110296A1 (en) 2012-10-19 2014-04-24 Medtronic Ardian Luxembourg S.A.R.L. Packaging for Catheter Treatment Devices and Associated Devices, Systems, and Methods
AU2013344780B2 (en) 2012-11-15 2018-03-01 Incyte Holdings Corporation Sustained-release dosage forms of ruxolitinib
EP2934667A1 (en) 2012-12-24 2015-10-28 E-Motion Medical, Ltd. Gi tract stimulation devices and methods
US10220211B2 (en) 2013-01-22 2019-03-05 Livanova Usa, Inc. Methods and systems to diagnose depression
WO2014118782A2 (en) * 2013-01-31 2014-08-07 Digma Medical Ltd. Methods and systems for reducing neural activity in an organ of a subject
JP5945061B2 (en) * 2013-02-13 2016-07-05 ハバロン メヂ アンド ビューティー カンパニー リミテッド Portable high-frequency treatment device with built-in battery
US9498619B2 (en) 2013-02-26 2016-11-22 Endostim, Inc. Implantable electrical stimulation leads
RS58547B1 (en) 2013-03-06 2019-05-31 Incyte Holdings Corp Processes and intermediates for making a jak inhibitor
US9011365B2 (en) 2013-03-12 2015-04-21 Medibotics Llc Adjustable gastrointestinal bifurcation (AGB) for reduced absorption of unhealthy food
US9067070B2 (en) 2013-03-12 2015-06-30 Medibotics Llc Dysgeusia-inducing neurostimulation for modifying consumption of a selected nutrient type
BR112015023344B1 (en) 2013-03-15 2022-05-31 Baronova, Inc Device for intermittently occluding a gastric opening; and reconfiguration method installing an occlusion device
US9056195B2 (en) 2013-03-15 2015-06-16 Cyberonics, Inc. Optimization of cranial nerve stimulation to treat seizure disorderse during sleep
CN105307719B (en) 2013-05-30 2018-05-29 格雷厄姆·H.·克雷西 Local nerve stimulation instrument
US11229789B2 (en) 2013-05-30 2022-01-25 Neurostim Oab, Inc. Neuro activator with controller
US9895539B1 (en) 2013-06-10 2018-02-20 Nevro Corp. Methods and systems for disease treatment using electrical stimulation
PT3030227T (en) 2013-08-07 2020-06-25 Incyte Corp Sustained release dosage forms for a jak1 inhibitor
CN105848708A (en) 2013-09-03 2016-08-10 恩多斯蒂姆股份有限公司 Methods and systems of electrode polarity switching in electrical stimulation therapy
WO2015068167A2 (en) 2013-11-06 2015-05-14 Enopace Biomedical Ltd. Wireless endovascular stent-based electrodes
US10149978B1 (en) 2013-11-07 2018-12-11 Nevro Corp. Spinal cord modulation for inhibiting pain via short pulse width waveforms, and associated systems and methods
CN105899256A (en) * 2013-11-20 2016-08-24 恩多斯蒂姆股份有限公司 Systems and methods for electrical stimulation of biological systems
WO2015103512A2 (en) * 2014-01-06 2015-07-09 Ohio State Innovation Foundation Neuromodulatory systems and methods for treating functional gastrointestinal disorders
US10123896B2 (en) 2014-03-06 2018-11-13 Mayo Foundation For Medical Education And Research Apparatus and methods of inducing weight loss using blood flow control
US10194979B1 (en) 2014-03-28 2019-02-05 Medtronic Ardian Luxembourg S.A.R.L. Methods for catheter-based renal neuromodulation
US10194980B1 (en) 2014-03-28 2019-02-05 Medtronic Ardian Luxembourg S.A.R.L. Methods for catheter-based renal neuromodulation
US9980766B1 (en) 2014-03-28 2018-05-29 Medtronic Ardian Luxembourg S.A.R.L. Methods and systems for renal neuromodulation
US20150272813A1 (en) * 2014-03-31 2015-10-01 Regents Of The University Of Minnesota Systems and methods for electrical stimulation of the gastrointestinal tract for treatment of post-operative ileus
EP3578228B1 (en) 2014-04-17 2022-02-16 Digma Medical Ltd. Systems for blocking neural activity in the duodenum
US9302109B2 (en) 2014-04-25 2016-04-05 Cyberonics, Inc. Cranial nerve stimulation to treat depression during sleep
US9585611B2 (en) 2014-04-25 2017-03-07 Cyberonics, Inc. Detecting seizures based on heartbeat data
WO2015184305A1 (en) 2014-05-30 2015-12-03 Incyte Corporation TREATMENT OF CHRONIC NEUTROPHILIC LEUKEMIA (CNL) AND ATYPICAL CHRONIC MYELOID LEUKEMIA (aCML) BY INHIBITORS OF JAK1
US11311725B2 (en) 2014-10-24 2022-04-26 Setpoint Medical Corporation Systems and methods for stimulating and/or monitoring loci in the brain to treat inflammation and to enhance vagus nerve stimulation
US9919152B2 (en) 2014-11-05 2018-03-20 Enterastim, Inc. Conditional gastrointestinal stimulation for improved motility
US9682234B2 (en) 2014-11-17 2017-06-20 Endostim, Inc. Implantable electro-medical device programmable for improved operational life
WO2016126807A1 (en) 2015-02-03 2016-08-11 Setpoint Medical Corporation Apparatus and method for reminding, prompting, or alerting a patient with an implanted stimulator
US11077301B2 (en) 2015-02-21 2021-08-03 NeurostimOAB, Inc. Topical nerve stimulator and sensor for bladder control
US10864367B2 (en) 2015-02-24 2020-12-15 Elira, Inc. Methods for using an electrical dermal patch in a manner that reduces adverse patient reactions
US9956393B2 (en) 2015-02-24 2018-05-01 Elira, Inc. Systems for increasing a delay in the gastric emptying time for a patient using a transcutaneous electro-dermal patch
US10335302B2 (en) 2015-02-24 2019-07-02 Elira, Inc. Systems and methods for using transcutaneous electrical stimulation to enable dietary interventions
US10376145B2 (en) 2015-02-24 2019-08-13 Elira, Inc. Systems and methods for enabling a patient to achieve a weight loss objective using an electrical dermal patch
US10765863B2 (en) 2015-02-24 2020-09-08 Elira, Inc. Systems and methods for using a transcutaneous electrical stimulation device to deliver titrated therapy
WO2016138176A1 (en) 2015-02-24 2016-09-01 Elira Therapeutics Llc Systems and methods for enabling appetite modulation and/or improving dietary compliance using an electro-dermal patch
US11318310B1 (en) 2015-10-26 2022-05-03 Nevro Corp. Neuromodulation for altering autonomic functions, and associated systems and methods
US10531907B2 (en) 2015-11-20 2020-01-14 Covidien Lp Devices, systems, and methods for treating ulcerative colitis and other inflammatory bowel diseases
US10596367B2 (en) 2016-01-13 2020-03-24 Setpoint Medical Corporation Systems and methods for establishing a nerve block
US10314501B2 (en) 2016-01-20 2019-06-11 Setpoint Medical Corporation Implantable microstimulators and inductive charging systems
US11471681B2 (en) 2016-01-20 2022-10-18 Setpoint Medical Corporation Batteryless implantable microstimulators
US10695569B2 (en) 2016-01-20 2020-06-30 Setpoint Medical Corporation Control of vagal stimulation
AU2017211121B2 (en) 2016-01-25 2022-02-24 Nevro Corp. Treatment of congestive heart failure with electrical stimulation, and associated systems and methods
US10583304B2 (en) 2016-01-25 2020-03-10 Setpoint Medical Corporation Implantable neurostimulator having power control and thermal regulation and methods of use
US10799701B2 (en) 2016-03-30 2020-10-13 Nevro Corp. Systems and methods for identifying and treating patients with high-frequency electrical signals
US10779980B2 (en) 2016-04-27 2020-09-22 Synerz Medical, Inc. Intragastric device for treating obesity
US11446504B1 (en) 2016-05-27 2022-09-20 Nevro Corp. High frequency electromagnetic stimulation for modulating cells, including spontaneously active and quiescent cells, and associated systems and methods
CN114569245A (en) 2016-08-14 2022-06-03 迪格玛医疗有限公司 Device and method for nerve ablation in the wall of the gastrointestinal tract
US10575904B1 (en) 2016-08-14 2020-03-03 Digma Medical Ltd. Apparatus and method for selective submucosal ablation
WO2018094207A1 (en) 2016-11-17 2018-05-24 Endostim, Inc. Modular stimulation system for the treatment of gastrointestinal disorders
US11083613B2 (en) 2017-01-23 2021-08-10 Baronova, Inc. Gastric obstruction device deployment assembly and methods of delivering and deploying a gastric obstruction device
US11173307B2 (en) 2017-08-14 2021-11-16 Setpoint Medical Corporation Vagus nerve stimulation pre-screening test
US10953225B2 (en) 2017-11-07 2021-03-23 Neurostim Oab, Inc. Non-invasive nerve activator with adaptive circuit
TW201924683A (en) 2017-12-08 2019-07-01 美商英塞特公司 Low dose combination therapy for treatment of myeloproliferative neoplasms
CA3085452A1 (en) 2017-12-13 2019-06-20 Neuros Medical, Inc. Nerve cuff deployment devices
US11864907B2 (en) 2018-01-16 2024-01-09 Boston Scientific Scimed, Inc. Devices, systems, and methods for monitoring gastrointestinal motility
CN112105608B (en) 2018-01-30 2023-07-14 因赛特公司 Process for the preparation of (1- (3-fluoro-2- (trifluoromethyl) isonicotinyl) piperidin-4-one
MX2022012285A (en) 2018-03-30 2023-08-15 Incyte Corp Treatment of hidradenitis suppurativa using jak inhibitors.
BR112020020867A2 (en) 2018-04-09 2021-01-26 Neuros Medical, Inc. apparatus and methods for adjusting electrical dose
US10835747B2 (en) 2018-09-24 2020-11-17 Vorso Corp. Auricular nerve stimulation to address patient disorders, and associated systems and methods
US11260229B2 (en) 2018-09-25 2022-03-01 The Feinstein Institutes For Medical Research Methods and apparatuses for reducing bleeding via coordinated trigeminal and vagal nerve stimulation
JP2020089723A (en) * 2018-12-07 2020-06-11 アヴェント インコーポレイテッド Device and method for selectively and reversibly modulating nervous system structure to inhibit perception of pain
AU2020207940A1 (en) 2019-01-17 2021-08-12 Nevro Corp. Sensory threshold and/or adaptation for neurological therapy screening and/or parameter selection, and associated systems and methods
US11590352B2 (en) 2019-01-29 2023-02-28 Nevro Corp. Ramped therapeutic signals for modulating inhibitory interneurons, and associated systems and methods
KR20220025834A (en) 2019-06-26 2022-03-03 뉴로스팀 테크놀로지스 엘엘씨 Non-invasive neural activators with adaptive circuits
IL293085A (en) 2019-11-22 2022-07-01 Incyte Corp Combination therapy comprising an alk2 inhibitor and a jak2 inhibitor
WO2021126921A1 (en) 2019-12-16 2021-06-24 Neurostim Solutions, Llc Non-invasive nerve activator with boosted charge delivery
US20230018722A1 (en) * 2019-12-17 2023-01-19 The Bionics Institute Of Australia Methods and System for Modulating Glycaemia
WO2021163308A1 (en) 2020-02-11 2021-08-19 Neuros Medical, Inc. System and method for quantifying qualitative patient-reported data sets
US11559385B2 (en) 2020-04-24 2023-01-24 Jt Godfrey, Llc Device for use with body tissue sphincters
US11628052B2 (en) 2020-05-13 2023-04-18 Jt Godfrey, Llc Device for use with body tissue sphincters
WO2021236977A1 (en) 2020-05-21 2021-11-25 The Feinstein Institutes For Medical Research Systems and methods for vagus nerve stimulation
US11833155B2 (en) 2020-06-03 2023-12-05 Incyte Corporation Combination therapy for treatment of myeloproliferative neoplasms
US11400299B1 (en) 2021-09-14 2022-08-02 Rainbow Medical Ltd. Flexible antenna for stimulator

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5263480A (en) * 1991-02-01 1993-11-23 Cyberonics, Inc. Treatment of eating disorders by nerve stimulation
US20010012828A1 (en) * 1999-10-12 2001-08-09 Aoki Kei Roger Intraspinal botulinum toxin for treating pain
US20020055779A1 (en) * 1996-03-05 2002-05-09 Brian J. Andrews Neural prosthesis

Family Cites Families (223)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US127953A (en) * 1872-06-18 Improvement in processes for purifying iron, steel, and other metals
US181958A (en) * 1876-09-05 Improvement in mop-heads
US181959A (en) * 1876-09-05 Improvement in combined spading, plowing, and stalk-cutting machines
US3128760A (en) * 1961-08-21 1964-04-14 Winston Electronics Ltd Vagotomy test apparatus
US3411507A (en) * 1964-04-01 1968-11-19 Medtronic Inc Method of gastrointestinal stimulation with electrical pulses
US4315503A (en) * 1976-11-17 1982-02-16 Electro-Biology, Inc. Modification of the growth, repair and maintenance behavior of living tissues and cells by a specific and selective change in electrical environment
US4114625A (en) * 1976-12-02 1978-09-19 Onat Mustafa V Anti-vomiting, anti-aspirating oral-nasal gastric tube
US4198963A (en) * 1978-10-19 1980-04-22 Michigan Instruments, Inc. Cardiopulmonary resuscitator, defibrillator and monitor
US4441210A (en) 1981-09-18 1984-04-03 Hochmair Erwin S Transcutaneous signal transmission system and methods
US5370675A (en) 1992-08-12 1994-12-06 Vidamed, Inc. Medical probe device and method
CA1215128A (en) 1982-12-08 1986-12-09 Pedro Molina-Negro Electric nerve stimulator device
US4702254A (en) * 1983-09-14 1987-10-27 Jacob Zabara Neurocybernetic prosthesis
US5025807A (en) * 1983-09-14 1991-06-25 Jacob Zabara Neurocybernetic prosthesis
US4867164A (en) * 1983-09-14 1989-09-19 Jacob Zabara Neurocybernetic prosthesis
AT385894B (en) * 1985-10-04 1988-05-25 Basem Dr Nashef TUBULAR PROBE
US5226426A (en) * 1990-12-18 1993-07-13 Inbae Yoon Safety penetrating instrument
US5188104A (en) * 1991-02-01 1993-02-23 Cyberonics, Inc. Treatment of eating disorders by nerve stimulation
US5269303A (en) * 1991-02-22 1993-12-14 Cyberonics, Inc. Treatment of dementia by nerve stimulation
US5199430A (en) * 1991-03-11 1993-04-06 Case Western Reserve University Micturitional assist device
US5215086A (en) * 1991-05-03 1993-06-01 Cyberonics, Inc. Therapeutic treatment of migraine symptoms by stimulation
US5299569A (en) * 1991-05-03 1994-04-05 Cyberonics, Inc. Treatment of neuropsychiatric disorders by nerve stimulation
US5335657A (en) * 1991-05-03 1994-08-09 Cyberonics, Inc. Therapeutic treatment of sleep disorder by nerve stimulation
US5226429A (en) * 1991-06-20 1993-07-13 Inamed Development Co. Laparoscopic gastric band and method
US5231988A (en) * 1991-08-09 1993-08-03 Cyberonics, Inc. Treatment of endocrine disorders by nerve stimulation
IT1260485B (en) * 1992-05-29 1996-04-09 PROCEDURE AND DEVICE FOR THE TREATMENT OF THE OBESITY OF A PATIENT
US5330515A (en) * 1992-06-17 1994-07-19 Cyberonics, Inc. Treatment of pain by vagal afferent stimulation
US5292344A (en) * 1992-07-10 1994-03-08 Douglas Donald D Percutaneously placed electrical gastrointestinal pacemaker stimulatory system, sensing system, and pH monitoring system, with optional delivery port
US5344438A (en) 1993-04-16 1994-09-06 Medtronic, Inc. Cuff electrode
US5601604A (en) * 1993-05-27 1997-02-11 Inamed Development Co. Universal gastric band
US5620955A (en) * 1993-06-18 1997-04-15 Peptide Technologies Corporation Bombesin receptor antagonists and uses thereof
US5437291A (en) * 1993-08-26 1995-08-01 Univ Johns Hopkins Method for treating gastrointestinal muscle disorders and other smooth muscle dysfunction
US6974578B1 (en) 1993-12-28 2005-12-13 Allergan, Inc. Method for treating secretions and glands using botulinum toxin
US6405732B1 (en) * 1994-06-24 2002-06-18 Curon Medical, Inc. Method to treat gastric reflux via the detection and ablation of gastro-esophageal nerves and receptors
US5514175A (en) * 1994-11-09 1996-05-07 Cerebral Stimulation, Inc. Auricular electrical stimulator
US5571150A (en) * 1994-12-19 1996-11-05 Cyberonics, Inc. Treatment of patients in coma by nerve stimulation
US6558708B1 (en) 1995-05-17 2003-05-06 Cedars-Sinai Medical Center Methods for manipulating upper gastrointestinal transit, blood flow, and satiety, and for treating visceral hyperalgesia
US5540730A (en) * 1995-06-06 1996-07-30 Cyberonics, Inc. Treatment of motility disorders by nerve stimulation
US5707400A (en) * 1995-09-19 1998-01-13 Cyberonics, Inc. Treating refractory hypertension by nerve stimulation
US5747060A (en) 1996-03-26 1998-05-05 Euro-Celtique, S.A. Prolonged local anesthesia with colchicine
US6735471B2 (en) * 1996-04-30 2004-05-11 Medtronic, Inc. Method and system for endotracheal/esophageal stimulation prior to and during a medical procedure
US6532388B1 (en) 1996-04-30 2003-03-11 Medtronic, Inc. Method and system for endotracheal/esophageal stimulation prior to and during a medical procedure
US5690691A (en) * 1996-05-08 1997-11-25 The Center For Innovative Technology Gastro-intestinal pacemaker having phased multi-point stimulation
US6865423B2 (en) 1996-06-13 2005-03-08 The Victoria University Of Manchester Stimulation of muscles
AU4107297A (en) * 1996-09-05 1998-03-26 Governors Of The University Of Alberta, The Gastro-intestinal electrical pacemaker
US5716385A (en) * 1996-11-12 1998-02-10 University Of Virginia Crural diaphragm pacemaker and method for treating esophageal reflux disease
US6026326A (en) * 1997-01-13 2000-02-15 Medtronic, Inc. Apparatus and method for treating chronic constipation
JP3246374B2 (en) 1997-01-13 2002-01-15 株式会社日立製作所 Magnetic recording device using magnetoresistive element
US5749907A (en) * 1997-02-18 1998-05-12 Pacesetter, Inc. System and method for identifying and displaying medical data which violate programmable alarm conditions
EP1666087A3 (en) 1997-02-26 2009-04-29 The Alfred E Mann Foundation for Scientific Research Battery-powered patient implantable device
US5830434A (en) 1997-02-26 1998-11-03 Medical University Of South Carolina Foundation For Research Development Methods of treating non-insulin dependent diabetes mellitus with pancreatic polypeptide
US5938596A (en) 1997-03-17 1999-08-17 Medtronic, Inc. Medical electrical lead
US5861014A (en) * 1997-04-30 1999-01-19 Medtronic, Inc. Method and apparatus for sensing a stimulating gastrointestinal tract on-demand
US5836994A (en) * 1997-04-30 1998-11-17 Medtronic, Inc. Method and apparatus for electrical stimulation of the gastrointestinal tract
US6216039B1 (en) * 1997-05-02 2001-04-10 Medtronic Inc. Method and apparatus for treating irregular gastric rhythms
US6093167A (en) * 1997-06-16 2000-07-25 Medtronic, Inc. System for pancreatic stimulation and glucose measurement
US5919216A (en) * 1997-06-16 1999-07-06 Medtronic, Inc. System and method for enhancement of glucose production by stimulation of pancreatic beta cells
EP1779890B8 (en) * 1997-07-16 2009-07-08 Metacure Limited Smooth muscle controller
IT1293974B1 (en) 1997-08-13 1999-03-15 Sorin Biomedica Cardio Spa ACTIVE IMPLANTABLE DEVICE.
US6479523B1 (en) 1997-08-26 2002-11-12 Emory University Pharmacologic drug combination in vagal-induced asystole
US5967977A (en) * 1997-10-03 1999-10-19 Medtronic, Inc. Transesophageal medical lead
US6091992A (en) * 1997-12-15 2000-07-18 Medtronic, Inc. Method and apparatus for electrical stimulation of the gastrointestinal tract
US6104955A (en) * 1997-12-15 2000-08-15 Medtronic, Inc. Method and apparatus for electrical stimulation of the gastrointestinal tract
US6364899B1 (en) 1998-01-23 2002-04-02 Innercool Therapies, Inc. Heat pipe nerve cooler
US7468060B2 (en) * 1998-02-19 2008-12-23 Respiratory Diagnostic, Inc. Systems and methods for treating obesity and other gastrointestinal conditions
PT1089733E (en) 1998-06-15 2005-08-31 Sepracor Inc USE OF (+) - OPORELY PURE NORCISAPRIDE FOR TREATMENT OF COLON IRRITAVEL SYNDROME
US6148222A (en) * 1998-07-10 2000-11-14 Cardiocommand, Inc. Esophageal catheters and method of use
US6002964A (en) 1998-07-15 1999-12-14 Feler; Claudio A. Epidural nerve root stimulation
US6587725B1 (en) 1998-07-27 2003-07-01 Dominique Durand Method and apparatus for closed-loop stimulation of the hypoglossal nerve in human patients to treat obstructive sleep apnea
US7599736B2 (en) 2001-07-23 2009-10-06 Dilorenzo Biomedical, Llc Method and apparatus for neuromodulation and physiologic modulation for the treatment of metabolic and neuropsychiatric disease
DE19847446B4 (en) 1998-10-08 2010-04-22 Biotronik Gmbh & Co. Kg Nerve electrode assembly
US6366814B1 (en) * 1998-10-26 2002-04-02 Birinder R. Boveja External stimulator for adjunct (add-on) treatment for neurological, neuropsychiatric, and urological disorders
US20030212440A1 (en) * 2002-05-09 2003-11-13 Boveja Birinder R. Method and system for modulating the vagus nerve (10th cranial nerve) using modulated electrical pulses with an inductively coupled stimulation system
US20050137644A1 (en) 1998-10-26 2005-06-23 Boveja Birinder R. Method and system for vagal blocking and/or vagal stimulation to provide therapy for obesity and other gastrointestinal disorders
US6611715B1 (en) 1998-10-26 2003-08-26 Birinder R. Boveja Apparatus and method for neuromodulation therapy for obesity and compulsive eating disorders using an implantable lead-receiver and an external stimulator
US7076307B2 (en) * 2002-05-09 2006-07-11 Boveja Birinder R Method and system for modulating the vagus nerve (10th cranial nerve) with electrical pulses using implanted and external components, to provide therapy neurological and neuropsychiatric disorders
US6097984A (en) * 1998-11-25 2000-08-01 Medtronic, Inc. System and method of stimulation for treating gastro-esophageal reflux disease
US6624150B2 (en) * 1999-02-26 2003-09-23 Inspire Pharmaceuticals, Inc. Method of treating gastrointestinal tract disease with purinergic receptor agonists
IL129032A (en) 1999-03-17 2006-12-31 Moshe Dudai Gastric band
US6261280B1 (en) * 1999-03-22 2001-07-17 Medtronic, Inc Method of obtaining a measure of blood glucose
US6098629A (en) * 1999-04-07 2000-08-08 Endonetics, Inc. Submucosal esophageal bulking device
US6895278B1 (en) 1999-04-14 2005-05-17 Transneuronix, Inc. Gastric stimulator apparatus and method for use
US6341236B1 (en) * 1999-04-30 2002-01-22 Ivan Osorio Vagal nerve stimulation techniques for treatment of epileptic seizures
US7840278B1 (en) 1999-06-25 2010-11-23 Puskas John D Devices and methods for vagus nerve stimulation
US6587719B1 (en) * 1999-07-01 2003-07-01 Cyberonics, Inc. Treatment of obesity by bilateral vagus nerve stimulation
US7149773B2 (en) 1999-07-07 2006-12-12 Medtronic, Inc. System and method of automated invoicing for communications between an implantable medical device and a remote computer system or health care provider
US6308105B1 (en) 1999-07-15 2001-10-23 Medtronic Inc. Medical electrical stimulation system using an electrode assembly having opposing semi-circular arms
US6473644B1 (en) * 1999-10-13 2002-10-29 Cyberonics, Inc. Method to enhance cardiac capillary growth in heart failure patients
US6853862B1 (en) * 1999-12-03 2005-02-08 Medtronic, Inc. Gastroelectric stimulation for influencing pancreatic secretions
WO2001039763A2 (en) * 1999-12-06 2001-06-07 Rhode Island Hospital, A Lifespan Partner Use of methylol-containing compounds for the manufacture of a medicament for the treatment of tumors
IT1315260B1 (en) 1999-12-07 2003-02-03 Valerio Cigaina REMOVABLE GASTRIC BANDAGE
US6418346B1 (en) * 1999-12-14 2002-07-09 Medtronic, Inc. Apparatus and method for remote therapy and diagnosis in medical devices via interface systems
SE9904626D0 (en) 1999-12-16 1999-12-16 Pacesetter Ab Programming system for medical devices
US6261572B1 (en) * 2000-01-11 2001-07-17 Allergan Sales, Inc. Method for treating a pancreatic disorder with a neurotoxin
US6600953B2 (en) * 2000-12-11 2003-07-29 Impulse Dynamics N.V. Acute and chronic electrical signal therapy for obesity
US6612983B1 (en) 2000-03-28 2003-09-02 Medtronic, Inc. Pancreatic secretion response to stimulation test protocol
US6826428B1 (en) 2000-04-11 2004-11-30 The Board Of Regents Of The University Of Texas System Gastrointestinal electrical stimulation
US6610713B2 (en) * 2000-05-23 2003-08-26 North Shore - Long Island Jewish Research Institute Inhibition of inflammatory cytokine production by cholinergic agonists and vagus nerve stimulation
US6306423B1 (en) 2000-06-02 2001-10-23 Allergan Sales, Inc. Neurotoxin implant
US20020072780A1 (en) * 2000-09-26 2002-06-13 Transneuronix, Inc. Method and apparatus for intentional impairment of gastric motility and /or efficiency by triggered electrical stimulation of the gastrointestinal tract with respect to the intrinsic gastric electrical activity
US7623926B2 (en) 2000-09-27 2009-11-24 Cvrx, Inc. Stimulus regimens for cardiovascular reflex control
US6591137B1 (en) 2000-11-09 2003-07-08 Neuropace, Inc. Implantable neuromuscular stimulator for the treatment of gastrointestinal disorders
US6832114B1 (en) * 2000-11-21 2004-12-14 Advanced Bionics Corporation Systems and methods for modulation of pancreatic endocrine secretion and treatment of diabetes
US20020094962A1 (en) * 2000-12-01 2002-07-18 Gary Ashley Motilide compounds
US6609025B2 (en) * 2001-01-02 2003-08-19 Cyberonics, Inc. Treatment of obesity by bilateral sub-diaphragmatic nerve stimulation
US6754536B2 (en) * 2001-01-31 2004-06-22 Medtronic, Inc Implantable medical device affixed internally within the gastrointestinal tract
WO2002065896A2 (en) * 2001-02-20 2002-08-29 Case Western Reserve University Systems and methods for reversibly blocking nerve activity
US6761715B2 (en) 2001-04-26 2004-07-13 Ronald J. Carroll Method and device for neurocryo analgesia and anesthesia
US6684105B2 (en) * 2001-08-31 2004-01-27 Biocontrol Medical, Ltd. Treatment of disorders by unidirectional nerve stimulation
US6907295B2 (en) * 2001-08-31 2005-06-14 Biocontrol Medical Ltd. Electrode assembly for nerve control
AU2002305357A1 (en) 2001-05-01 2002-11-11 Second Sight, Llc High-density array of micro-machined electrodes for neural stimulation
US7702394B2 (en) 2001-05-01 2010-04-20 Intrapace, Inc. Responsive gastric stimulator
JP4289886B2 (en) * 2001-05-09 2009-07-01 バイオインターラクションズ リミテッド Wound closure system and method
US6928320B2 (en) 2001-05-17 2005-08-09 Medtronic, Inc. Apparatus for blocking activation of tissue or conduction of action potentials while other tissue is being therapeutically activated
US6901295B2 (en) * 2001-07-14 2005-05-31 Virender K. Sharma Method and apparatus for electrical stimulation of the lower esophageal sphincter
US20060116736A1 (en) 2001-07-23 2006-06-01 Dilorenzo Daniel J Method, apparatus, and surgical technique for autonomic neuromodulation for the treatment of obesity
US6622038B2 (en) * 2001-07-28 2003-09-16 Cyberonics, Inc. Treatment of movement disorders by near-diaphragmatic nerve stimulation
US20040036377A1 (en) * 2001-08-15 2004-02-26 Steven Mezinis High voltage lc electric and magnetic field motivator
US20040193230A1 (en) 2001-08-17 2004-09-30 Overstreet Edward H. Gradual recruitment of muscle/neural excitable tissue using high-rate electrical stimulation parameters
US6600956B2 (en) * 2001-08-21 2003-07-29 Cyberonics, Inc. Circumneural electrode assembly
US6760626B1 (en) * 2001-08-29 2004-07-06 Birinder R. Boveja Apparatus and method for treatment of neurological and neuropsychiatric disorders using programmerless implantable pulse generator system
US7885709B2 (en) * 2001-08-31 2011-02-08 Bio Control Medical (B.C.M.) Ltd. Nerve stimulation for treating disorders
US7974693B2 (en) 2001-08-31 2011-07-05 Bio Control Medical (B.C.M.) Ltd. Techniques for applying, configuring, and coordinating nerve fiber stimulation
US7734355B2 (en) 2001-08-31 2010-06-08 Bio Control Medical (B.C.M.) Ltd. Treatment of disorders by unidirectional nerve stimulation
US7778703B2 (en) * 2001-08-31 2010-08-17 Bio Control Medical (B.C.M.) Ltd. Selective nerve fiber stimulation for treating heart conditions
US7254444B2 (en) * 2001-10-17 2007-08-07 Encore Medical Asset Corporation Electrical nerve stimulation device
US7187978B2 (en) 2001-11-01 2007-03-06 Medtronic, Inc. Method and apparatus for programming an implantable medical device
US7050856B2 (en) * 2002-01-11 2006-05-23 Medtronic, Inc. Variation of neural-stimulation parameters
US7035691B2 (en) 2002-01-15 2006-04-25 Therapeutic Innovations, Inc. Resonant muscle stimulator
US6910604B2 (en) * 2002-01-17 2005-06-28 Carmine Gugliotti Kitchen sink top-mounted rigid stem-portable dispenser soap system
US20080147137A1 (en) 2002-01-23 2008-06-19 Biocontrol Medical Ltd. Inhibition of sympathetic nerves
US6721603B2 (en) * 2002-01-25 2004-04-13 Cyberonics, Inc. Nerve stimulation as a treatment for pain
US20030144708A1 (en) 2002-01-29 2003-07-31 Starkebaum Warren L. Methods and apparatus for retarding stomach emptying for treatment of eating disorders
US6985773B2 (en) 2002-02-07 2006-01-10 Cardiac Pacemakers, Inc. Methods and apparatuses for implantable medical device telemetry power management
US7317948B1 (en) 2002-02-12 2008-01-08 Boston Scientific Scimed, Inc. Neural stimulation system providing auto adjustment of stimulus output as a function of sensed impedance
US7239912B2 (en) 2002-03-22 2007-07-03 Leptos Biomedical, Inc. Electric modulation of sympathetic nervous system
US7236822B2 (en) * 2002-03-22 2007-06-26 Leptos Biomedical, Inc. Wireless electric modulation of sympathetic nervous system
US7689277B2 (en) 2002-03-22 2010-03-30 Leptos Biomedical, Inc. Neural stimulation for treatment of metabolic syndrome and type 2 diabetes
US7551964B2 (en) 2002-03-22 2009-06-23 Leptos Biomedical, Inc. Splanchnic nerve stimulation for treatment of obesity
US7702386B2 (en) 2002-03-22 2010-04-20 Leptos Biomedical, Inc. Nerve stimulation for treatment of obesity, metabolic syndrome, and Type 2 diabetes
US7689276B2 (en) 2002-09-13 2010-03-30 Leptos Biomedical, Inc. Dynamic nerve stimulation for treatment of disorders
US8145316B2 (en) * 2002-04-08 2012-03-27 Ardian, Inc. Methods and apparatus for renal neuromodulation
US20040015201A1 (en) 2002-04-22 2004-01-22 Transneuronix, Inc. Process for electrostimulation treatment of obesity
US20040193229A1 (en) 2002-05-17 2004-09-30 Medtronic, Inc. Gastric electrical stimulation for treatment of gastro-esophageal reflux disease
US20050065553A1 (en) 2003-06-13 2005-03-24 Omry Ben Ezra Applications of vagal stimulation
GB2405592A (en) * 2002-05-29 2005-03-09 Oklahoma Foundation For Digest Spinal cord stimulation as treatment for functional bowel disorders
US6746474B2 (en) * 2002-05-31 2004-06-08 Vahid Saadat Apparatus and methods for cooling a region within the body
US7292890B2 (en) 2002-06-20 2007-11-06 Advanced Bionics Corporation Vagus nerve stimulation via unidirectional propagation of action potentials
US6938135B1 (en) * 2002-10-04 2005-08-30 Veritas Operating Corporation Incremental backup of a data volume
US8543214B2 (en) 2002-10-15 2013-09-24 Medtronic, Inc. Configuring and testing treatment therapy parameters for a medical device system
US7236830B2 (en) 2002-12-10 2007-06-26 Northstar Neuroscience, Inc. Systems and methods for enhancing or optimizing neural stimulation therapy for treating symptoms of Parkinson's disease and/or other movement disorders
US7238357B2 (en) 2002-11-05 2007-07-03 Allergan, Inc. Methods for treating ulcers and gastroesophageal reflux disease
US6736722B1 (en) * 2002-12-04 2004-05-18 Deere & Company Unloader tube cleaning system for harvesting apparatus
US6990376B2 (en) 2002-12-06 2006-01-24 The Regents Of The University Of California Methods and systems for selective control of bladder function
US7933654B2 (en) 2002-12-17 2011-04-26 Massachusetts Eye & Ear Infirmary Vestibular stimulator
US8064994B2 (en) 2003-01-14 2011-11-22 The United States Of America As Represented By The Department Of Veterans Affairs Cervical vagal stimulation induced weight loss
US7167750B2 (en) * 2003-02-03 2007-01-23 Enteromedics, Inc. Obesity treatment with electrically induced vagal down regulation
US7844338B2 (en) 2003-02-03 2010-11-30 Enteromedics Inc. High frequency obesity treatment
US20040172084A1 (en) * 2003-02-03 2004-09-02 Knudson Mark B. Method and apparatus for treatment of gastro-esophageal reflux disease (GERD)
US7613515B2 (en) * 2003-02-03 2009-11-03 Enteromedics Inc. High frequency vagal blockage therapy
US7430449B2 (en) 2003-03-14 2008-09-30 Endovx, Inc. Methods and apparatus for testing disruption of a vagal nerve
US7783358B2 (en) 2003-03-14 2010-08-24 Endovx, Inc. Methods and apparatus for treatment of obesity with an ultrasound device movable in two or three axes
US7684865B2 (en) 2003-03-14 2010-03-23 Endovx, Inc. Methods and apparatus for treatment of obesity
US20060015151A1 (en) 2003-03-14 2006-01-19 Aldrich William N Method of using endoscopic truncal vagoscopy with gastric bypass, gastric banding and other procedures
US7142250B1 (en) 2003-04-05 2006-11-28 Apple Computer, Inc. Method and apparatus for synchronizing audio and video streams
DE10318071A1 (en) 2003-04-17 2004-11-25 Forschungszentrum Jülich GmbH Device for desynchronizing neuronal brain activity
US7444184B2 (en) 2003-05-11 2008-10-28 Neuro And Cardial Technologies, Llc Method and system for providing therapy for bulimia/eating disorders by providing electrical pulses to vagus nerve(s)
US7742818B2 (en) * 2003-05-19 2010-06-22 Medtronic, Inc. Gastro-electric stimulation for increasing the acidity of gastric secretions or increasing the amounts thereof
US7620454B2 (en) * 2003-05-19 2009-11-17 Medtronic, Inc. Gastro-electric stimulation for reducing the acidity of gastric secretions or reducing the amounts thereof
US7149574B2 (en) * 2003-06-09 2006-12-12 Palo Alto Investors Treatment of conditions through electrical modulation of the autonomic nervous system
US7263405B2 (en) * 2003-08-27 2007-08-28 Neuro And Cardiac Technologies Llc System and method for providing electrical pulses to the vagus nerve(s) to provide therapy for obesity, eating disorders, neurological and neuropsychiatric disorders with a stimulator, comprising bi-directional communication and network capabilities
US20050070970A1 (en) 2003-09-29 2005-03-31 Knudson Mark B. Movement disorder stimulation with neural block
US20050070974A1 (en) 2003-09-29 2005-03-31 Knudson Mark B. Obesity and eating disorder stimulation treatment with neural block
US8265770B2 (en) * 2003-10-02 2012-09-11 Medtronic, Inc. Driver circuitry switchable between energy transfer and telemetry for an implantable medical device
US7991479B2 (en) 2003-10-02 2011-08-02 Medtronic, Inc. Neurostimulator programmer with clothing attachable antenna
US20050143378A1 (en) * 2003-12-29 2005-06-30 Yun Anthony J. Treatment of conditions through pharmacological modulation of the autonomic nervous system
US7054690B2 (en) * 2003-10-22 2006-05-30 Intrapace, Inc. Gastrointestinal stimulation device
WO2005051486A1 (en) 2003-11-28 2005-06-09 University Technologies International Inc. Method and apparatus for gastrointestinal motility control
US7177693B2 (en) * 2004-01-07 2007-02-13 Medtronic, Inc. Gastric stimulation for altered perception to treat obesity
WO2006017634A2 (en) * 2004-08-04 2006-02-16 Ndi Medical, Llc Devices, systems, and methods employing a molded nerve cuff electrode
US8452407B2 (en) 2004-08-16 2013-05-28 Boston Scientific Neuromodulation Corporation Methods for treating gastrointestinal disorders
US8214047B2 (en) 2004-09-27 2012-07-03 Advanced Neuromodulation Systems, Inc. Method of using spinal cord stimulation to treat gastrointestinal and/or eating disorders or conditions
EP1827580A1 (en) 2004-10-21 2007-09-05 Advanced Neuromodulation Systems, Inc. New stimulation design for neuromodulation
US20060161217A1 (en) 2004-12-21 2006-07-20 Jaax Kristen N Methods and systems for treating obesity
US8260426B2 (en) 2008-01-25 2012-09-04 Cyberonics, Inc. Method, apparatus and system for bipolar charge utilization during stimulation by an implantable medical device
US9339190B2 (en) 2005-02-17 2016-05-17 Metacure Limited Charger with data transfer capabilities
US7310557B2 (en) 2005-04-29 2007-12-18 Maschino Steven E Identification of electrodes for nerve stimulation in the treatment of eating disorders
US7899540B2 (en) 2005-04-29 2011-03-01 Cyberonics, Inc. Noninvasively adjustable gastric band
US7774069B2 (en) 2005-04-29 2010-08-10 Medtronic, Inc. Alignment indication for transcutaneous energy transfer
US7561923B2 (en) 2005-05-09 2009-07-14 Cardiac Pacemakers, Inc. Method and apparatus for controlling autonomic balance using neural stimulation
US7343539B2 (en) 2005-06-24 2008-03-11 The United States Of America As Represented By The United States National Aeronautics And Space Administration ARA type protograph codes
US20070016262A1 (en) 2005-07-13 2007-01-18 Betastim, Ltd. Gi and pancreatic device for treating obesity and diabetes
US20070027484A1 (en) * 2005-07-28 2007-02-01 Cyberonics, Inc. Autonomic nerve stimulation to treat a pancreatic disorder
US7672727B2 (en) * 2005-08-17 2010-03-02 Enteromedics Inc. Neural electrode treatment
US7822486B2 (en) 2005-08-17 2010-10-26 Enteromedics Inc. Custom sized neural electrodes
US7551960B2 (en) 2005-09-08 2009-06-23 Medtronic, Inc. External presentation of electrical stimulation parameters
US7620455B2 (en) 2005-10-25 2009-11-17 Cyberonics, Inc. Cranial nerve stimulation to treat eating disorders
US20070100377A1 (en) * 2005-10-28 2007-05-03 Cyberonics, Inc. Providing multiple signal modes for a medical device
US8041428B2 (en) 2006-02-10 2011-10-18 Electrocore Llc Electrical stimulation treatment of hypotension
EP1981584B1 (en) 2006-02-03 2015-05-13 Interventional Autonomics Corporation Intravascular device for neuromodulation
US20070191912A1 (en) 2006-02-10 2007-08-16 Vision Quest Industries, Inc. Interactive electrical stimulator device and server-based support system
AU2006337679A1 (en) 2006-02-10 2007-08-16 Electrocore, Inc. Methods and apparatus for treating anaphylaxis using electrical modulation
ES2538726T3 (en) 2006-03-29 2015-06-23 Dignity Health Vagus nerve stimulation system
US8187297B2 (en) 2006-04-19 2012-05-29 Vibsynt, Inc. Devices and methods for treatment of obesity
WO2007137026A2 (en) 2006-05-18 2007-11-29 Cedars-Sinai Medical Center Electrical stimulation of the lower esophageal sphincter
US7738961B2 (en) 2006-10-09 2010-06-15 Endostim, Inc. Method and apparatus for treatment of the gastrointestinal tract
US7729760B2 (en) 2006-10-27 2010-06-01 Cyberonics, Inc. Patient management system for providing parameter data for an implantable medical device
US7706875B2 (en) 2007-01-25 2010-04-27 Cyberonics, Inc. Modulation of drug effects by vagus nerve stimulation
AU2008216316A1 (en) 2007-02-13 2008-08-21 Virender K. Sharma Method and apparatus for electrical stimulation of the pancreatico-biliary system
US8068918B2 (en) 2007-03-09 2011-11-29 Enteromedics Inc. Remote monitoring and control of implantable devices
US20080300657A1 (en) 2007-05-31 2008-12-04 Mark Raymond Stultz Therapy system
US8103399B2 (en) 2007-06-05 2012-01-24 Snap-On Incorporated System and method for transferring vehicle service data
WO2009064408A1 (en) 2007-11-12 2009-05-22 Dilorenzo Daniel J Method and apparatus for programming of autonomic neuromodulation for the treatment of obesity
US9186502B2 (en) 2008-02-14 2015-11-17 Enteromedics Inc. Treatment of excess weight by neural downregulation in combination with compositions
US7917226B2 (en) 2008-04-23 2011-03-29 Enteromedics Inc. Antenna arrangements for implantable therapy device
US8204603B2 (en) 2008-04-25 2012-06-19 Cyberonics, Inc. Blocking exogenous action potentials by an implantable medical device
US20090275997A1 (en) 2008-05-01 2009-11-05 Michael Allen Faltys Vagus nerve stimulation electrodes and methods of use
DE202010017584U1 (en) 2009-05-08 2012-02-29 Université Libre de Bruxelles Gastrointestinal device
BR112012001910A2 (en) 2009-09-21 2019-09-24 Medtronic Inc waveforms for electrical stimulation therapy
AU2011258026A1 (en) 2010-05-27 2012-12-20 Ndi Medical, Llc Waveform shapes for treating neurological disorders optimized for energy efficiency
AU2011282294B9 (en) 2010-07-19 2014-09-25 Cardiac Pacemakers, Inc. Minimally invasive lead system for vagus nerve stimulation
US20130184775A1 (en) 2010-10-01 2013-07-18 Indiana University Research & Technology Corporation Long term vagal nerve stimulation for therapeutic and diagnostic treatment
WO2012060874A2 (en) 2010-11-01 2012-05-10 Udaya Sankar Devanaboyina Methods for diagnosis and treatment of disorders of the gastrointestinal tract. and apparatus for use therewith
EP2635344B1 (en) 2010-11-03 2015-07-08 The Cleveland Clinic Foundation Apparatus for energy efficient stimulation

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5263480A (en) * 1991-02-01 1993-11-23 Cyberonics, Inc. Treatment of eating disorders by nerve stimulation
US20020055779A1 (en) * 1996-03-05 2002-05-09 Brian J. Andrews Neural prosthesis
US20010012828A1 (en) * 1999-10-12 2001-08-09 Aoki Kei Roger Intraspinal botulinum toxin for treating pain

Also Published As

Publication number Publication date
US20070135856A1 (en) 2007-06-14
EP1601414A2 (en) 2005-12-07
US7444183B2 (en) 2008-10-28
US20130197600A1 (en) 2013-08-01
US7167750B2 (en) 2007-01-23
US7986995B2 (en) 2011-07-26
US7693577B2 (en) 2010-04-06
US7720540B2 (en) 2010-05-18
US8369952B2 (en) 2013-02-05
US20040172088A1 (en) 2004-09-02
US9586046B2 (en) 2017-03-07
WO2004069331B1 (en) 2005-03-17
US7630769B2 (en) 2009-12-08
WO2004069331A2 (en) 2004-08-19
US20040167583A1 (en) 2004-08-26
US8862233B2 (en) 2014-10-14
US20070135858A1 (en) 2007-06-14
US20070135846A1 (en) 2007-06-14
US20070142870A1 (en) 2007-06-21
US20150012065A1 (en) 2015-01-08
EP1601414B1 (en) 2012-02-29
US20070135857A1 (en) 2007-06-14
US20110270344A1 (en) 2011-11-03

Similar Documents

Publication Publication Date Title
WO2004069331A3 (en) Neural stimulation
WO2005011805A3 (en) Apparatus and methods for applying neural stimulation to a patient
WO2006073484A3 (en) Treating inflammatory disorders by electrical vagus nerve stimulation
ATE507872T1 (en) DEVICE FOR TREATING EPILEPSY AND RHYTHM DISORDERS
AU2003264847A1 (en) Nerve stimulation for treating spasticity, tremor, muscle weakness, and other motor disorders
WO2005087307A3 (en) Neuromuscular stimulation
WO2003026736A3 (en) Methods and implantable apparatus for electrical therapy
WO2003041559A3 (en) Electrical stimulation of the sympathetic nerve chain
WO2004022156A3 (en) Methods for treating central nervous system damage
DE502004009540D1 (en) DEVICE FOR THE DESYNCHRONIZATION OF NEURONAL BRAIN ACTIVITY
GB0402569D0 (en) Nerve and/or muscle stimulation electrodes
DE60332269D1 (en) DEVICE FOR ADJUSTING STIMULATION OF NERVES
WO2007033290A3 (en) Optical vestibular stimulator
AU2003231344A1 (en) Selective nerve fiber stimulation for treating heart conditions
WO2007117728A3 (en) Non-linear electrode array
WO2004052183A3 (en) Systems and methods for enhancing or optimizing neural stimulation therapy for treating symptoms of parkinson's disease and/or other movement disorders
GB202213010D0 (en) Neuromodulation system and neuromodulation stimulator based on the same
WO2005016287A3 (en) Prkwnks as modifiers of the rac pathway and methods of use
EP1633880A4 (en) Mptens as modifiers of the pten/igf pathway and methods of use
WO2004024882A3 (en) FLJ20647s AS MODIFIERS OF THE p21 PATHWAY AND METHODS OF USE
WO2008070585A3 (en) Gastrointestinal electrical stimulation for the treatment of visceral pain
Joshi et al. Modeling auditory-nerve responses to electrical stimulation
WO2004005483A3 (en) ADCY3S AS MODIFIERS OF THE p21 PATHWAY AND METHODS OF USE
WO2004015073A3 (en) MP21S AS MODIFIERS OF THE p21 PATHWAY AND METHODS OF USE
WO2004005486A3 (en) Mp21s as modifiers of the p21 pathway and methods of use

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BW BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE EG ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NA NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SY TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): BW GH GM KE LS MW MZ SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LU MC NL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
B Later publication of amended claims

Effective date: 20041202

WWE Wipo information: entry into national phase

Ref document number: 2004707122

Country of ref document: EP

WWP Wipo information: published in national office

Ref document number: 2004707122

Country of ref document: EP

DPEN Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed from 20040101)