WO2004091389A1 - A non-invasive sensor to visually analyze the level of muscle activity - Google Patents
A non-invasive sensor to visually analyze the level of muscle activity Download PDFInfo
- Publication number
- WO2004091389A1 WO2004091389A1 PCT/BE2004/000054 BE2004000054W WO2004091389A1 WO 2004091389 A1 WO2004091389 A1 WO 2004091389A1 BE 2004000054 W BE2004000054 W BE 2004000054W WO 2004091389 A1 WO2004091389 A1 WO 2004091389A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- sensing device
- patient
- muscle activity
- sensor
- muscle
- Prior art date
Links
- 210000003205 muscle Anatomy 0.000 title claims abstract description 29
- 230000000694 effects Effects 0.000 title claims abstract description 24
- 238000000034 method Methods 0.000 claims description 7
- 229920000642 polymer Polymers 0.000 claims description 6
- 238000003745 diagnosis Methods 0.000 description 4
- 206010044565 Tremor Diseases 0.000 description 3
- 239000002322 conducting polymer Substances 0.000 description 3
- 229920001940 conductive polymer Polymers 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 206010011953 Decreased activity Diseases 0.000 description 2
- 208000014094 Dystonic disease Diseases 0.000 description 2
- 230000008602 contraction Effects 0.000 description 2
- 208000035475 disorder Diseases 0.000 description 2
- 208000010118 dystonia Diseases 0.000 description 2
- 208000018360 neuromuscular disease Diseases 0.000 description 2
- 208000002343 primary orthostatic tremor Diseases 0.000 description 2
- 210000001364 upper extremity Anatomy 0.000 description 2
- 208000002033 Myoclonus Diseases 0.000 description 1
- 208000018737 Parkinson disease Diseases 0.000 description 1
- 206010037211 Psychomotor hyperactivity Diseases 0.000 description 1
- 239000000556 agonist Substances 0.000 description 1
- 239000005557 antagonist Substances 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 238000001647 drug administration Methods 0.000 description 1
- 201000006517 essential tremor Diseases 0.000 description 1
- 230000005021 gait Effects 0.000 description 1
- 208000013403 hyperactivity Diseases 0.000 description 1
- 210000002414 leg Anatomy 0.000 description 1
- 210000003141 lower extremity Anatomy 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 210000001087 myotubule Anatomy 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 230000001360 synchronised effect Effects 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- 210000000689 upper leg Anatomy 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
- 230000002747 voluntary effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/41—Detecting, measuring or recording for evaluating the immune or lymphatic systems
- A61B5/411—Detecting or monitoring allergy or intolerance reactions to an allergenic agent or substance
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
- A61B5/25—Bioelectric electrodes therefor
- A61B5/279—Bioelectric electrodes therefor specially adapted for particular uses
- A61B5/296—Bioelectric electrodes therefor specially adapted for particular uses for electromyography [EMG]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/74—Details of notification to user or communication with user or patient ; user input means
- A61B5/742—Details of notification to user or communication with user or patient ; user input means using visual displays
- A61B5/7445—Display arrangements, e.g. multiple display units
Abstract
The present invention is related to a sensing device for measuring muscle activity comprising an interface with electrodes (3), an active amplifier (4) and an electronic circuit (6) being in connection with a digital/video display (7).
Description
A NON-INVASIVE SENSOR TO VISUALLY ANALYZE THE LEVEL OF
MUSCLE ACTIVITY
Field of the invention
[0001] The present invention concerns a new tool (non-invasive, lightweight, ergonomic and portable) to analyze the level of muscle activity visually.
Background of the invention
[0002] Classical study of muscle activity in human requires the use of cables linked to an acquisition unit . EMG activity is recorded either using needle electrodes/wires inserted in the muscle, either using surface EMG electrodes. So far, there is no technique available to estimate visually and in colour the voluntary (such as a movement of the hand or the neck) or involuntary (such as tremor or dystonia) muscle activity, taking into account ergonomics (a tool which would be lightweight, portable and without cables) , and non-invasively. Such a tool would be of great help and benefit for the non- invasive follow-up of patients and for the diagnosis of neuromuscular diseases. For instance, the diagnosis of diseases like torticolis, hand dystonia, upper limb tremor would be easier.
Summary of the invention
[0003] The new sensor according to the invention combines the use of active differential electromyographic
electrodes fixed directly on the skin (2) such as a Delsys electrode (www.delsys.com/products/electrodes.htm) coupled to digital video display preferably coupled to semiconducting polymer LΞDs (7) . Semi-conducting polymer LEDs (7) are electroluminescent polymers such as the one described by Braun D., Semi -conducting polymer LEDs . Materials today. June 2002; Elsevier Science, pp . 32-39. These polymer LEDs (7) are flexible and present switch on and off characteristics suitable for video display (10) applications.
[0004] Thanks to the development of active EMG electrodes, the signal-to-noise ratio is improved. These electrodes are directly fixed to the skin (2) of a patient.
The signal is amplified directly on the skin (2) and filters can be implemented in the amplifier.
[0005] The enclosed figures 1 to 3 show the characteristics of the (non-invasive, lightweight, ergonomic and portable by the patient) sensor, which can be applied directly upon the skin (2) of a patient in order to characterise the level of muscle (1) patient activity. The EMG electrode comprises an electrode interface (3) , an active amplifier (4) , a battery (5) , an electronic circuit
(6) connected to a semi-conducting polymer LED (7) .
[0006] In the figure 2 is presented the basic principle of the sensor presenting a video display for two colours. The EMG signal is therefore amplified and filtered. A rectifier (8) or inverter (11) can also be used.
[0007] The figure 3 presents a variant of the (colour-EMG) sensor according to the invention, which comprises a digital display (10) of the EMG activity. The numbers will appear according to the level of EMG activity.
Said system comprises also a classical analogue converter
(9) for a direct visual display.
[0008] The sensor according to the invention presents the following advantageous characteristics: [0009] The (colour-EMG) sensor of the invention is fixed on the skin of the neck in patients suffering from torticolis. The sensor informs the observer of the level of muscle hyperactivity (the colour selected is dependent on the level of EMG activity) . This procedure will improve the diagnosis, leading advantageously to a drug administration in the early stages of the disorder. [0010] Two units of (colour-EMG) sensor of the invention are fixed respectively on the flexor carpi radialis muscle and extensor carpi radialis muscle in a patient suffering from a upper limb tremor. The LEDs flash asynchronously in Parkinson's disease, whereas they flash synchronously in Essential Tremor. Furthermore, the level of EMG activity of each muscle will appear thanks to the colour flashing. Therefore, this technique can be used non- invasively or invasively, with the introduction of two fine wire electrodes in the muscle of the patient by the general practitioner.
[0011] This invention allows an analysis of the activity of muscle groups during clinical examination. Several (colour-EMG) sensors are fixed on the patient's lower limbs at the level of the thighs and the legs. This technique will help the neurologist to identify muscles which are overactive and those that are under-active during gait .
[0012] Furthermore, this sensor allows a diagnosis of primary orthostatic tremor (POT) . The (colour-EMG) sensor of the invention will flash at a high frequency (13 to 18 Hz) if fixed at the level of weight-bearing muscles while the patient is standing (this disorder is characterized by high-frequency synchronous discharges at a frequency of 13 to 18 Hz) .
[0013] The sensor can be used for the detection of myoclonus. The (colour-EMG) sensor of the invention will detect the brief and involuntary contractions (usually with a duration of less than 150 msec) by flashing on the skin. [0014] A "dream" for the rehabilitation specialists is to estimate visually and preferably non-invasively the activity of the muscle groups (agonists/antagonists /synergic) during rehabilitation. The (colour-EMG) sensor of the invention will help in this task by informing which muscle is active as compared to the other ones.
[0015] In addition, the sensor of the invention allows a non-invasive analysis of muscle activity following a hand grafting. These patients need to take imunosuppressive drugs. Therefore, needles are usually avoided. The (colour-EMG) sensor of the invention will help the therapist to follow the recovery.
[0016] The sensor of the invention can be used for analysis of EMG activity non-invasively in babies and in children, especially in intensive care units. [0017] The use of the (colour-EMG) sensor is also proposed in sports to estimate the level of contraction.
[0018] For a research perspective-, the sensor comprises fine wire electrodes (inserted in the muscle) , the (colour-EMG) sensor will be used to analyze the muscle activity in neuromuscular diseases. Advantageously, the analysis of the patient's muscle activity will be improved with the sensor according to the invention because the signal-to-noise ratio is increased compared • to a known technique that requires long connection means between a sensor and a recording apparatus.
[0019] A last aspect of the present invention is related to a method for measuring muscle activity of the patient, which comprises the step of maintaining the interface with
electrodes of the sensing device according to the invention upon the patient's skin for a sufficient time to obtain a measure and, possibly a recording of muscle activity of the patient .
[0020] Using several groups of wires inserted in the muscle or using multi-channels needles, the colour-EMG will allow to analyze simultaneously the activity of distinct groups of muscle fibers, to detect overactivity ou underactivity of different portions of the muscle
Claims
1. A sensing device for measuring muscle activity comprising an interface with electrodes (3) , an active amplifier (4) and an electronic circuit (6) being in connection with a digital/video display (7) .
2. The sensing device according to claim 1, wherein the video display comprises at least one polymer LED.
3. The sensing device according to claim 1 or 2 , wherein the active amplifier
(4) is provided with a battery. . The sensing device according to any of the claims 1 to 3, wherein the electronic circuit (6) further comprises a passive filter.
5. The sensing device according to claim 4, wherein the electronic circuit (6) further comprises a passive filter.
6. The sensing device according to any of the preceding claims 2 to 5, which comprises at least two polymer LEDs and wherein an inverter (11) is arranged between the electronic circuit (6) and one of the polymer LEDs .
7. The sensing device according to claim 1 , wherein an analogue converter (9) is arranged between the electronic circuit (6) and the digital/video display (7) .
8. The sensing device according to any of the preceding claims, wherein the interface (3) comprises fine wire electrodes .
9. The sensing device according to any of the preceding claims, which is portable by a patient.
10. A method for measuring muscle activity of a patient, which comprises the step of maintaining the interface with electrodes of the sensing device according to any of the preceding claims upon the patient's skin for-
a sufficient time to obtain a measure and, possibly, a recording of muscle activity of the patient .
Priority Applications (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2004229123A AU2004229123A1 (en) | 2003-04-16 | 2004-04-16 | A non-invasive sensor to visually analyze the level of muscle activity |
| BRPI0409755-6A BRPI0409755A (en) | 2003-04-16 | 2004-04-16 | sensor device and method for measuring muscle activity |
| CA002519876A CA2519876A1 (en) | 2003-04-16 | 2004-04-16 | A non-invasive sensor to visually analyze the level of muscle activity |
| JP2006504041A JP2006523472A (en) | 2003-04-16 | 2004-04-16 | Non-invasive sensor for visual analysis of the level of muscle activity |
| EP04727795A EP1617758A1 (en) | 2003-04-16 | 2004-04-16 | A non-invasive sensor to visually analyze the level of muscle activity |
| US11/251,108 US20060094975A1 (en) | 2003-04-16 | 2005-10-14 | Non-invasive sensor to analyze visually the level of muscle activity |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US46389703P | 2003-04-16 | 2003-04-16 | |
| US60/463,897 | 2003-04-16 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| US11/251,108 Continuation-In-Part US20060094975A1 (en) | 2003-04-16 | 2005-10-14 | Non-invasive sensor to analyze visually the level of muscle activity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| WO2004091389A1 true WO2004091389A1 (en) | 2004-10-28 |
Family
ID=33300096
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/BE2004/000054 WO2004091389A1 (en) | 2003-04-16 | 2004-04-16 | A non-invasive sensor to visually analyze the level of muscle activity |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20060094975A1 (en) |
| EP (1) | EP1617758A1 (en) |
| JP (1) | JP2006523472A (en) |
| CN (1) | CN1774201A (en) |
| AU (1) | AU2004229123A1 (en) |
| BR (1) | BRPI0409755A (en) |
| CA (1) | CA2519876A1 (en) |
| WO (1) | WO2004091389A1 (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1707121A1 (en) * | 2005-03-30 | 2006-10-04 | Universite Libre De Bruxelles | Device for measuring the rhythmic activity of muscle fibres |
| EP1759725A1 (en) | 2005-08-31 | 2007-03-07 | Université Libre De Bruxelles | Electro-biochemical probe for intramuscular and intracerebral analysis |
| US8301237B2 (en) | 2006-06-02 | 2012-10-30 | Koninklijke Philips Electronics N.V. | Biofeedback system and display device |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9820658B2 (en) | 2006-06-30 | 2017-11-21 | Bao Q. Tran | Systems and methods for providing interoperability among healthcare devices |
| US7733224B2 (en) | 2006-06-30 | 2010-06-08 | Bao Tran | Mesh network personal emergency response appliance |
| US8500636B2 (en) | 2006-05-12 | 2013-08-06 | Bao Tran | Health monitoring appliance |
| US7539532B2 (en) | 2006-05-12 | 2009-05-26 | Bao Tran | Cuffless blood pressure monitoring appliance |
| US8323189B2 (en) | 2006-05-12 | 2012-12-04 | Bao Tran | Health monitoring appliance |
| US8968195B2 (en) | 2006-05-12 | 2015-03-03 | Bao Tran | Health monitoring appliance |
| US9060683B2 (en) | 2006-05-12 | 2015-06-23 | Bao Tran | Mobile wireless appliance |
| US8684922B2 (en) | 2006-05-12 | 2014-04-01 | Bao Tran | Health monitoring system |
| US7558622B2 (en) | 2006-05-24 | 2009-07-07 | Bao Tran | Mesh network stroke monitoring appliance |
| US8684900B2 (en) | 2006-05-16 | 2014-04-01 | Bao Tran | Health monitoring appliance |
| US7539533B2 (en) | 2006-05-16 | 2009-05-26 | Bao Tran | Mesh network monitoring appliance |
| US8750971B2 (en) * | 2007-05-24 | 2014-06-10 | Bao Tran | Wireless stroke monitoring |
| EP2320793B1 (en) * | 2008-08-28 | 2020-12-16 | St. Michael's Hospital | Determining patient- ventilator breath contribution index in spontaneously breathing, mechanically ventilated patients |
| EP2840964B1 (en) * | 2012-04-27 | 2019-04-17 | Fibrux Oy | A method and a device for measuring muscle signals |
| US9865176B2 (en) | 2012-12-07 | 2018-01-09 | Koninklijke Philips N.V. | Health monitoring system |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5058602A (en) * | 1988-09-30 | 1991-10-22 | Brody Stanley R | Paraspinal electromyography scanning |
| US6002957A (en) * | 1997-04-15 | 1999-12-14 | Paraspinal Diagnostic Corporation | EMG electrode array support belt |
| WO2000051543A2 (en) * | 1999-03-03 | 2000-09-08 | S.L.P. Ltd. | A nocturnal muscle activity monitoring system |
| US20030043611A1 (en) * | 2000-03-17 | 2003-03-06 | Tridonicatco Gmbh & Co. Kg | Drive for light-emitting diodes |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4329898A1 (en) * | 1993-09-04 | 1995-04-06 | Marcus Dr Besson | Wireless medical diagnostic and monitoring device |
| AUPN205095A0 (en) * | 1995-03-29 | 1995-04-27 | University Of Queensland, The | Diagnosis of neuromuscular dysfunction |
| US6047202A (en) * | 1997-04-15 | 2000-04-04 | Paraspinal Diagnostic Corporation | EMG electrode |
| US6004312A (en) * | 1997-04-15 | 1999-12-21 | Paraspinal Diagnostic Corporation | Computerized EMG diagnostic system |
| US6216034B1 (en) * | 1997-08-01 | 2001-04-10 | Genetronics, Inc. | Method of programming an array of needle electrodes for electroporation therapy of tissue |
| US6635989B1 (en) * | 1998-08-03 | 2003-10-21 | E. I. Du Pont De Nemours And Company | Encapsulation of polymer-based solid state devices with inorganic materials |
| EP1777255A3 (en) * | 1999-06-11 | 2007-07-11 | Sydney Hyman | Image making medium |
| TW559746B (en) * | 2001-05-15 | 2003-11-01 | Koninkl Philips Electronics Nv | Method of driving an organic electroluminescent display device and display device suitable for said method |
| US6816744B2 (en) * | 2001-05-29 | 2004-11-09 | Reproductive Health Technologies, Inc. | Device and system for remote for in-clinic trans-abdominal/vaginal/cervical acquisition, and detection, analysis, and communication of maternal uterine and maternal and fetal cardiac and fetal brain activity from electrical signals |
| WO2005007223A2 (en) * | 2003-07-16 | 2005-01-27 | Sasha John | Programmable medical drug delivery systems and methods for delivery of multiple fluids and concentrations |
| US20060194724A1 (en) * | 2005-02-25 | 2006-08-31 | Whitehurst Todd K | Methods and systems for nerve regeneration |
-
2004
- 2004-04-16 WO PCT/BE2004/000054 patent/WO2004091389A1/en not_active Application Discontinuation
- 2004-04-16 CN CNA2004800100907A patent/CN1774201A/en active Pending
- 2004-04-16 BR BRPI0409755-6A patent/BRPI0409755A/en not_active IP Right Cessation
- 2004-04-16 EP EP04727795A patent/EP1617758A1/en not_active Ceased
- 2004-04-16 JP JP2006504041A patent/JP2006523472A/en not_active Abandoned
- 2004-04-16 CA CA002519876A patent/CA2519876A1/en not_active Abandoned
- 2004-04-16 AU AU2004229123A patent/AU2004229123A1/en not_active Abandoned
-
2005
- 2005-10-14 US US11/251,108 patent/US20060094975A1/en not_active Abandoned
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5058602A (en) * | 1988-09-30 | 1991-10-22 | Brody Stanley R | Paraspinal electromyography scanning |
| US6002957A (en) * | 1997-04-15 | 1999-12-14 | Paraspinal Diagnostic Corporation | EMG electrode array support belt |
| WO2000051543A2 (en) * | 1999-03-03 | 2000-09-08 | S.L.P. Ltd. | A nocturnal muscle activity monitoring system |
| US20030043611A1 (en) * | 2000-03-17 | 2003-03-06 | Tridonicatco Gmbh & Co. Kg | Drive for light-emitting diodes |
Non-Patent Citations (1)
| Title |
|---|
| See also references of EP1617758A1 * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1707121A1 (en) * | 2005-03-30 | 2006-10-04 | Universite Libre De Bruxelles | Device for measuring the rhythmic activity of muscle fibres |
| WO2006102724A1 (en) * | 2005-03-30 | 2006-10-05 | Universite Libre De Bruxelles | Device for measuring a value corresponding to a muscular tremor |
| EP1759725A1 (en) | 2005-08-31 | 2007-03-07 | Université Libre De Bruxelles | Electro-biochemical probe for intramuscular and intracerebral analysis |
| US8301237B2 (en) | 2006-06-02 | 2012-10-30 | Koninklijke Philips Electronics N.V. | Biofeedback system and display device |
Also Published As
| Publication number | Publication date |
|---|---|
| CA2519876A1 (en) | 2004-10-28 |
| EP1617758A1 (en) | 2006-01-25 |
| BRPI0409755A (en) | 2006-05-09 |
| CN1774201A (en) | 2006-05-17 |
| US20060094975A1 (en) | 2006-05-04 |
| AU2004229123A1 (en) | 2004-10-28 |
| JP2006523472A (en) | 2006-10-19 |
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