WO2004101025A3 - Needle free hypodermic injector and ampule for intradermal, subcutaneous and intramuscular injection - Google Patents

Needle free hypodermic injector and ampule for intradermal, subcutaneous and intramuscular injection Download PDF

Info

Publication number
WO2004101025A3
WO2004101025A3 PCT/US2004/014511 US2004014511W WO2004101025A3 WO 2004101025 A3 WO2004101025 A3 WO 2004101025A3 US 2004014511 W US2004014511 W US 2004014511W WO 2004101025 A3 WO2004101025 A3 WO 2004101025A3
Authority
WO
WIPO (PCT)
Prior art keywords
ampule
medicament
injection mechanism
generating means
injector
Prior art date
Application number
PCT/US2004/014511
Other languages
French (fr)
Other versions
WO2004101025A2 (en
Inventor
John Deslierres
Conrad Anstead
Robert W Brant
Original Assignee
Intravacc Inc
John Deslierres
Conrad Anstead
Robert W Brant
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/603,496 external-priority patent/US6939319B1/en
Application filed by Intravacc Inc, John Deslierres, Conrad Anstead, Robert W Brant filed Critical Intravacc Inc
Priority to US10/555,742 priority Critical patent/US20070167907A1/en
Priority to JP2006532903A priority patent/JP2007518460A/en
Publication of WO2004101025A2 publication Critical patent/WO2004101025A2/en
Publication of WO2004101025A3 publication Critical patent/WO2004101025A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/30—Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/002—Packages specially adapted therefor, e.g. for syringes or needles, kits for diabetics
    • A61M2005/005—Magazines with multiple ampoules directly inserted into an injection or infusion device, e.g. revolver-like magazines containing ampoules with or without needles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M2005/2418—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic comprising means for damping shocks on ampoule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/204—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically connected to external reservoirs for multiple refilling
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/42—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for desensitising skin, for protruding skin to facilitate piercing, or for locating point where body is to be pierced
    • A61M5/425—Protruding skin to facilitate piercing, e.g. vacuum cylinders, vein immobilising means

Abstract

A needle free hypodermic injector (20) comprising a hand manipulatable elongate housing (21), an impact impulse injection mechanism (30) within the housing, a suction generating means (35) within the housing and cooperable with the impact impulse injection mechanism (30), a safety interlock mechanism (36), at least one medicament containing ampule (25) cooperable with the impact impulse injection mechanism and the suction generating means and having a jet orifice (66) through which medicament is injectable through a skin surface in response to an impulse placed on the medicament by the impact impulse injection mechanism, and means to receive and hold the ampule on the injector in registration with the impact impulse injection mechanism and in communication with the suction generating means; whereby the injector is adapted to expel the medicament from the ampule in a jet stream of sufficient velocity to penetrate skin tissue held against the orifice by the suction generating means and to deposit the medicament intradermally, subcutaneously or intramuscularly based on the position and angle of the jet orifice.
PCT/US2004/014511 2002-11-20 2004-05-10 Needle free hypodermic injector and ampule for intradermal, subcutaneous and intramuscular injection WO2004101025A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US10/555,742 US20070167907A1 (en) 2002-11-20 2004-05-10 Needle free hypodermic injector and ampule for intradermal, subcutaneous and intramuscular injection
JP2006532903A JP2007518460A (en) 2003-05-09 2004-05-10 Needleless syringes and ampoules for intradermal, subcutaneous and intramuscular injection

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US46944303P 2003-05-09 2003-05-09
US60/469,443 2003-05-09
US10/603,496 2003-06-25
US10/603,496 US6939319B1 (en) 2002-11-20 2003-06-25 Process and device for single use, needle-free intradermal, subcutaneous, or intramuscular injections

Publications (2)

Publication Number Publication Date
WO2004101025A2 WO2004101025A2 (en) 2004-11-25
WO2004101025A3 true WO2004101025A3 (en) 2005-06-09

Family

ID=33457141

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/014511 WO2004101025A2 (en) 2002-11-20 2004-05-10 Needle free hypodermic injector and ampule for intradermal, subcutaneous and intramuscular injection

Country Status (2)

Country Link
JP (1) JP2007518460A (en)
WO (1) WO2004101025A2 (en)

Families Citing this family (42)

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GB2414402B (en) 2004-05-28 2009-04-22 Cilag Ag Int Injection device
GB2414775B (en) 2004-05-28 2008-05-21 Cilag Ag Int Releasable coupling and injection device
GB2414400B (en) 2004-05-28 2009-01-14 Cilag Ag Int Injection device
US20060089593A1 (en) * 2004-10-26 2006-04-27 Sergio Landau Needle-free injection device for individual users
EP2532378B1 (en) * 2004-12-01 2016-04-27 AcuShot, Inc. Needle-free injector
US20060258986A1 (en) * 2005-02-11 2006-11-16 Hunter Ian W Controlled needle-free transport
BRPI0607934A2 (en) * 2005-02-11 2009-10-20 Massachusetts Inst Technology needle-free transdermal transport device for transferring a substance across a biological body surface, linear electromagnetic actuator and methods for transferring a substance and treating a disease
US7833189B2 (en) 2005-02-11 2010-11-16 Massachusetts Institute Of Technology Controlled needle-free transport
GB2427826B (en) 2005-04-06 2010-08-25 Cilag Ag Int Injection device comprising a locking mechanism associated with integrally formed biasing means
GB2425062B (en) 2005-04-06 2010-07-21 Cilag Ag Int Injection device
GB2424836B (en) 2005-04-06 2010-09-22 Cilag Ag Int Injection device (bayonet cap removal)
DE602005018480D1 (en) 2005-08-30 2010-02-04 Cilag Gmbh Int Needle device for a prefilled syringe
US20110098656A1 (en) 2005-09-27 2011-04-28 Burnell Rosie L Auto-injection device with needle protecting cap having outer and inner sleeves
GB2438591B (en) 2006-06-01 2011-07-13 Cilag Gmbh Int Injection device
GB2438590B (en) 2006-06-01 2011-02-09 Cilag Gmbh Int Injection device
GB2438593B (en) 2006-06-01 2011-03-30 Cilag Gmbh Int Injection device (cap removal feature)
CN101588829A (en) 2006-09-01 2009-11-25 麻省理工学院 Needle-free injector device with autoloading capability
EP3520840B1 (en) * 2008-03-14 2022-05-04 Boehringer Ingelheim Animal Health USA Inc. Veterinary syringe for multiple injections
GB2461086B (en) 2008-06-19 2012-12-05 Cilag Gmbh Int Injection device
GB2461089B (en) 2008-06-19 2012-09-19 Cilag Gmbh Int Injection device
GB2461085B (en) 2008-06-19 2012-08-29 Cilag Gmbh Int Injection device
GB2461084B (en) 2008-06-19 2012-09-26 Cilag Gmbh Int Fluid transfer assembly
GB2461087B (en) 2008-06-19 2012-09-26 Cilag Gmbh Int Injection device
EP2198904A1 (en) * 2008-12-19 2010-06-23 Sanofi-Aventis Deutschland GmbH Interlock mechanism for a drug delivery device and drug delivery device
WO2011028719A2 (en) 2009-09-01 2011-03-10 Massachusetts Institute Of Technology Nonlinear system identification techniques and devices for discovering dynamic and static tissue properties
GB201017363D0 (en) * 2010-10-14 2010-11-24 Owen Mumford Ltd Injection devices
US20110143310A1 (en) 2009-12-15 2011-06-16 Hunter Ian W Lorentz-Force Actuated Cleaning Device
WO2012137072A1 (en) 2011-04-06 2012-10-11 Biovaxim Limited Therapeutic vaccine compositions inducing tolerance to hiv for treating hiv infections in humans
CN105709221B (en) 2011-04-06 2020-11-17 拜欧瓦克西姆有限公司 Pharmaceutical composition for the prevention and/or treatment of HIV diseases in humans
JP2013059424A (en) 2011-09-12 2013-04-04 Daicel Corp Needleless syringe
RU2627632C2 (en) * 2011-12-13 2017-08-09 Фармаджет Инк. Needle-free intradermal injection device
GB2515032A (en) 2013-06-11 2014-12-17 Cilag Gmbh Int Guide for an injection device
GB2515039B (en) 2013-06-11 2015-05-27 Cilag Gmbh Int Injection Device
GB2517896B (en) 2013-06-11 2015-07-08 Cilag Gmbh Int Injection device
GB2515038A (en) 2013-06-11 2014-12-17 Cilag Gmbh Int Injection device
JP6468581B2 (en) * 2014-02-19 2019-02-13 株式会社ダイセル Needleless syringe
WO2015153900A1 (en) * 2014-04-02 2015-10-08 Zogenix, Inc. Kits for drug delivery site preparation
WO2016181377A1 (en) 2015-05-10 2016-11-17 Kolorpen Ltd. Device and method for repetitive needleless injection
CN107921215B (en) 2015-08-18 2020-11-17 株式会社大赛璐 Needleless injector
KR101939954B1 (en) * 2018-07-30 2019-01-17 김명숙 Portable Skin Care Apparatus
CN111481774B (en) * 2019-01-25 2023-06-09 凯联医疗科技(上海)有限公司 Needleless syringe for trace medicine
IL310149A (en) 2021-07-15 2024-03-01 Allspim Compositions and methods for preventing and/or treating disease associated with il-23 expression

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US5911703A (en) * 1997-05-22 1999-06-15 Avant Drug Delivery Systems, Inc. Two-stage fluid medicament jet injector
US6406456B1 (en) * 2000-06-08 2002-06-18 Avant Drug Delivery Systems, Inc. Jet injector
US6652483B2 (en) * 2000-11-07 2003-11-25 Avant Drug Delivery Systems, Inc. Needleless jet injector system with separate drug reservoir
US6669664B2 (en) * 2001-09-07 2003-12-30 Avant Drug Delivery Systems, Inc. Vacuum control cycle for jet injector

Patent Citations (4)

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Publication number Priority date Publication date Assignee Title
US5911703A (en) * 1997-05-22 1999-06-15 Avant Drug Delivery Systems, Inc. Two-stage fluid medicament jet injector
US6406456B1 (en) * 2000-06-08 2002-06-18 Avant Drug Delivery Systems, Inc. Jet injector
US6652483B2 (en) * 2000-11-07 2003-11-25 Avant Drug Delivery Systems, Inc. Needleless jet injector system with separate drug reservoir
US6669664B2 (en) * 2001-09-07 2003-12-30 Avant Drug Delivery Systems, Inc. Vacuum control cycle for jet injector

Also Published As

Publication number Publication date
JP2007518460A (en) 2007-07-12
WO2004101025A2 (en) 2004-11-25

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