WO2005015156A3 - Molecular detector - Google Patents
Molecular detector Download PDFInfo
- Publication number
- WO2005015156A3 WO2005015156A3 PCT/US2004/025062 US2004025062W WO2005015156A3 WO 2005015156 A3 WO2005015156 A3 WO 2005015156A3 US 2004025062 W US2004025062 W US 2004025062W WO 2005015156 A3 WO2005015156 A3 WO 2005015156A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- detect
- detection surface
- electric charge
- electronic
- biomolecular
- Prior art date
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y15/00—Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/403—Cells and electrode assemblies
- G01N27/414—Ion-sensitive or chemical field-effect transistors, i.e. ISFETS or CHEMFETS
- G01N27/4145—Ion-sensitive or chemical field-effect transistors, i.e. ISFETS or CHEMFETS specially adapted for biomolecules, e.g. gate electrode with immobilised receptors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
- G01N33/5438—Electrodes
Abstract
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/567,233 US20090029353A1 (en) | 2003-12-08 | 2004-08-02 | Molecular detector |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US49254603P | 2003-08-04 | 2003-08-04 | |
US60/492,546 | 2003-08-04 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2005015156A2 WO2005015156A2 (en) | 2005-02-17 |
WO2005015156A3 true WO2005015156A3 (en) | 2005-05-26 |
Family
ID=34135148
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2004/025062 WO2005015156A2 (en) | 2003-08-04 | 2004-08-02 | Molecular detector |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2005015156A2 (en) |
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US8764969B2 (en) | 2006-12-14 | 2014-07-01 | Life Technologies Corporation | Methods for operating chemically sensitive sensors with sample and hold capacitors |
US8841217B1 (en) | 2013-03-13 | 2014-09-23 | Life Technologies Corporation | Chemical sensor with protruded sensor surface |
US8858782B2 (en) | 2010-06-30 | 2014-10-14 | Life Technologies Corporation | Ion-sensing charge-accumulation circuits and methods |
US8890216B2 (en) | 2006-12-14 | 2014-11-18 | Life Technologies Corporation | Methods and apparatus for measuring analytes using large scale FET arrays |
US8912580B2 (en) | 2009-05-29 | 2014-12-16 | Life Technologies Corporation | Active chemically-sensitive sensors with in-sensor current sources |
US8912005B1 (en) | 2010-09-24 | 2014-12-16 | Life Technologies Corporation | Method and system for delta double sampling |
US8936763B2 (en) | 2008-10-22 | 2015-01-20 | Life Technologies Corporation | Integrated sensor arrays for biological and chemical analysis |
US8963216B2 (en) | 2013-03-13 | 2015-02-24 | Life Technologies Corporation | Chemical sensor with sidewall spacer sensor surface |
US8962366B2 (en) | 2013-01-28 | 2015-02-24 | Life Technologies Corporation | Self-aligned well structures for low-noise chemical sensors |
US9116117B2 (en) | 2013-03-15 | 2015-08-25 | Life Technologies Corporation | Chemical sensor with sidewall sensor surface |
US9128044B2 (en) | 2013-03-15 | 2015-09-08 | Life Technologies Corporation | Chemical sensors with consistent sensor surface areas |
US9164070B2 (en) | 2010-06-30 | 2015-10-20 | Life Technologies Corporation | Column adc |
US9194000B2 (en) | 2008-06-25 | 2015-11-24 | Life Technologies Corporation | Methods and apparatus for measuring analytes using large scale FET arrays |
US9270264B2 (en) | 2012-05-29 | 2016-02-23 | Life Technologies Corporation | System for reducing noise in a chemical sensor array |
US9404920B2 (en) | 2006-12-14 | 2016-08-02 | Life Technologies Corporation | Methods and apparatus for detecting molecular interactions using FET arrays |
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US11339430B2 (en) | 2007-07-10 | 2022-05-24 | Life Technologies Corporation | Methods and apparatus for measuring analytes using large scale FET arrays |
US20120261274A1 (en) | 2009-05-29 | 2012-10-18 | Life Technologies Corporation | Methods and apparatus for measuring analytes |
US8776573B2 (en) | 2009-05-29 | 2014-07-15 | Life Technologies Corporation | Methods and apparatus for measuring analytes |
JP5952813B2 (en) | 2010-06-30 | 2016-07-13 | ライフ テクノロジーズ コーポレーション | Method and apparatus for testing ISFET arrays |
US11307166B2 (en) | 2010-07-01 | 2022-04-19 | Life Technologies Corporation | Column ADC |
EP2589065B1 (en) | 2010-07-03 | 2015-08-19 | Life Technologies Corporation | Chemically sensitive sensor with lightly doped drains |
WO2012036679A1 (en) | 2010-09-15 | 2012-03-22 | Life Technologies Corporation | Methods and apparatus for measuring analytes |
US9970984B2 (en) | 2011-12-01 | 2018-05-15 | Life Technologies Corporation | Method and apparatus for identifying defects in a chemical sensor array |
US9080968B2 (en) | 2013-01-04 | 2015-07-14 | Life Technologies Corporation | Methods and systems for point of use removal of sacrificial material |
US9841398B2 (en) | 2013-01-08 | 2017-12-12 | Life Technologies Corporation | Methods for manufacturing well structures for low-noise chemical sensors |
CN105051525B (en) | 2013-03-15 | 2019-07-26 | 生命科技公司 | Chemical device with thin conducting element |
CN105264366B (en) | 2013-03-15 | 2019-04-16 | 生命科技公司 | Chemical sensor with consistent sensor surface area |
US9835585B2 (en) | 2013-03-15 | 2017-12-05 | Life Technologies Corporation | Chemical sensor with protruded sensor surface |
US20140336063A1 (en) | 2013-05-09 | 2014-11-13 | Life Technologies Corporation | Windowed Sequencing |
US10458942B2 (en) | 2013-06-10 | 2019-10-29 | Life Technologies Corporation | Chemical sensor array having multiple sensors per well |
EP3180606A1 (en) | 2014-08-14 | 2017-06-21 | Regents of the University of Minnesota | Electrolyte-gated transistors for detection of molecules |
US10077472B2 (en) | 2014-12-18 | 2018-09-18 | Life Technologies Corporation | High data rate integrated circuit with power management |
EP3234575B1 (en) | 2014-12-18 | 2023-01-25 | Life Technologies Corporation | Apparatus for measuring analytes using large scale fet arrays |
KR102593647B1 (en) | 2014-12-18 | 2023-10-26 | 라이프 테크놀로지스 코포레이션 | High data rate integrated circuit with transmitter configuration |
US9702847B2 (en) * | 2014-12-30 | 2017-07-11 | Avails Medical, Inc. | Systems and methods for detecting a substance in bodily fluid |
JP2022543668A (en) | 2019-08-09 | 2022-10-13 | ナットクラッカー セラピューティクス, インコーポレイテッド | Microfluidic device and method of use |
CN114371159B (en) * | 2021-05-19 | 2023-11-07 | 南京医科大学第二附属医院 | RNA biochip, preparation method and application thereof |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
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US6225059B1 (en) * | 1993-11-01 | 2001-05-01 | Nanogen, Inc. | Advanced active electronic devices including collection electrodes for molecular biological analysis and diagnostics |
US6315953B1 (en) * | 1993-11-01 | 2001-11-13 | Nanogen, Inc. | Devices for molecular biological analysis and diagnostics including waveguides |
US6569630B1 (en) * | 1999-07-02 | 2003-05-27 | Conceptual Mindworks, Inc. | Methods and compositions for aptamers against anthrax |
US20030153024A1 (en) * | 2001-04-19 | 2003-08-14 | Sullivan Brian M | Charged bio-molecule/binding agent conjugate for biological capture |
-
2004
- 2004-08-02 WO PCT/US2004/025062 patent/WO2005015156A2/en active Application Filing
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6225059B1 (en) * | 1993-11-01 | 2001-05-01 | Nanogen, Inc. | Advanced active electronic devices including collection electrodes for molecular biological analysis and diagnostics |
US6315953B1 (en) * | 1993-11-01 | 2001-11-13 | Nanogen, Inc. | Devices for molecular biological analysis and diagnostics including waveguides |
US6569630B1 (en) * | 1999-07-02 | 2003-05-27 | Conceptual Mindworks, Inc. | Methods and compositions for aptamers against anthrax |
US20030153024A1 (en) * | 2001-04-19 | 2003-08-14 | Sullivan Brian M | Charged bio-molecule/binding agent conjugate for biological capture |
Cited By (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9134269B2 (en) | 2006-12-14 | 2015-09-15 | Life Technologies Corporation | Methods and apparatus for measuring analytes using large scale FET arrays |
US9404920B2 (en) | 2006-12-14 | 2016-08-02 | Life Technologies Corporation | Methods and apparatus for detecting molecular interactions using FET arrays |
US8890216B2 (en) | 2006-12-14 | 2014-11-18 | Life Technologies Corporation | Methods and apparatus for measuring analytes using large scale FET arrays |
US8764969B2 (en) | 2006-12-14 | 2014-07-01 | Life Technologies Corporation | Methods for operating chemically sensitive sensors with sample and hold capacitors |
US9269708B2 (en) | 2006-12-14 | 2016-02-23 | Life Technologies Corporation | Methods and apparatus for measuring analytes using large scale FET arrays |
US9023189B2 (en) | 2006-12-14 | 2015-05-05 | Life Technologies Corporation | High density sensor array without wells |
US9194000B2 (en) | 2008-06-25 | 2015-11-24 | Life Technologies Corporation | Methods and apparatus for measuring analytes using large scale FET arrays |
US8936763B2 (en) | 2008-10-22 | 2015-01-20 | Life Technologies Corporation | Integrated sensor arrays for biological and chemical analysis |
US8912580B2 (en) | 2009-05-29 | 2014-12-16 | Life Technologies Corporation | Active chemically-sensitive sensors with in-sensor current sources |
US8858782B2 (en) | 2010-06-30 | 2014-10-14 | Life Technologies Corporation | Ion-sensing charge-accumulation circuits and methods |
US9239313B2 (en) | 2010-06-30 | 2016-01-19 | Life Technologies Corporation | Ion-sensing charge-accumulation circuits and methods |
US9164070B2 (en) | 2010-06-30 | 2015-10-20 | Life Technologies Corporation | Column adc |
US8912005B1 (en) | 2010-09-24 | 2014-12-16 | Life Technologies Corporation | Method and system for delta double sampling |
US9110015B2 (en) | 2010-09-24 | 2015-08-18 | Life Technologies Corporation | Method and system for delta double sampling |
US9270264B2 (en) | 2012-05-29 | 2016-02-23 | Life Technologies Corporation | System for reducing noise in a chemical sensor array |
US8962366B2 (en) | 2013-01-28 | 2015-02-24 | Life Technologies Corporation | Self-aligned well structures for low-noise chemical sensors |
US8963216B2 (en) | 2013-03-13 | 2015-02-24 | Life Technologies Corporation | Chemical sensor with sidewall spacer sensor surface |
US8841217B1 (en) | 2013-03-13 | 2014-09-23 | Life Technologies Corporation | Chemical sensor with protruded sensor surface |
US9128044B2 (en) | 2013-03-15 | 2015-09-08 | Life Technologies Corporation | Chemical sensors with consistent sensor surface areas |
US9116117B2 (en) | 2013-03-15 | 2015-08-25 | Life Technologies Corporation | Chemical sensor with sidewall sensor surface |
Also Published As
Publication number | Publication date |
---|---|
WO2005015156A2 (en) | 2005-02-17 |
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