WO2005017185A3 - HEPATOCYTE NUCLEAR FACTOR 4α MODULATOR COMPOUNDS - Google Patents
HEPATOCYTE NUCLEAR FACTOR 4α MODULATOR COMPOUNDS Download PDFInfo
- Publication number
- WO2005017185A3 WO2005017185A3 PCT/US2004/022907 US2004022907W WO2005017185A3 WO 2005017185 A3 WO2005017185 A3 WO 2005017185A3 US 2004022907 W US2004022907 W US 2004022907W WO 2005017185 A3 WO2005017185 A3 WO 2005017185A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- compounds
- nuclear factor
- hepatocyte nuclear
- modulator compounds
- hnf
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
- C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D335/06—Benzothiopyrans; Hydrogenated benzothiopyrans
Abstract
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US48823703P | 2003-07-16 | 2003-07-16 | |
US60/488,237 | 2003-07-16 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2005017185A2 WO2005017185A2 (en) | 2005-02-24 |
WO2005017185A3 true WO2005017185A3 (en) | 2005-07-14 |
Family
ID=34193074
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2004/022907 WO2005017185A2 (en) | 2003-07-16 | 2004-07-16 | HEPATOCYTE NUCLEAR FACTOR 4α MODULATOR COMPOUNDS |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2005017185A2 (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2010127264A2 (en) * | 2009-04-30 | 2010-11-04 | Burnham Institute For Medical Research | HNF4α ANTAGONISTS AND METHODS OF USE |
US20100317706A1 (en) * | 2009-04-30 | 2010-12-16 | Bumham Institute For Medical Research | HNF4alpha MODULATORS AND METHODS OF USE |
CN107250112B (en) * | 2014-10-10 | 2021-04-23 | 高力研究有限公司 | Fluorescent synthetic retinoids |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5015658A (en) * | 1988-06-29 | 1991-05-14 | Allergan, Inc. | Thiochroman esters of phenols and terephthallates having retinoid-like activity |
US6391287B1 (en) * | 1999-05-06 | 2002-05-21 | L'oreal | Composition containing at least one bicyclic aromatic compound and at least one lipophilic sunscreen, and uses thereof |
-
2004
- 2004-07-16 WO PCT/US2004/022907 patent/WO2005017185A2/en active Application Filing
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5015658A (en) * | 1988-06-29 | 1991-05-14 | Allergan, Inc. | Thiochroman esters of phenols and terephthallates having retinoid-like activity |
US6391287B1 (en) * | 1999-05-06 | 2002-05-21 | L'oreal | Composition containing at least one bicyclic aromatic compound and at least one lipophilic sunscreen, and uses thereof |
Also Published As
Publication number | Publication date |
---|---|
WO2005017185A2 (en) | 2005-02-24 |
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