WO2005019413A3 - A low maintenance detector for biological agents - Google Patents

A low maintenance detector for biological agents Download PDF

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Publication number
WO2005019413A3
WO2005019413A3 PCT/US2004/018374 US2004018374W WO2005019413A3 WO 2005019413 A3 WO2005019413 A3 WO 2005019413A3 US 2004018374 W US2004018374 W US 2004018374W WO 2005019413 A3 WO2005019413 A3 WO 2005019413A3
Authority
WO
WIPO (PCT)
Prior art keywords
detection
sample
capture probes
cartridge
target molecule
Prior art date
Application number
PCT/US2004/018374
Other languages
French (fr)
Other versions
WO2005019413A2 (en
Inventor
Dennis M Connolly
David R Chafin
Original Assignee
Integrated Nano Tech Llc
Dennis M Connolly
David R Chafin
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Integrated Nano Tech Llc, Dennis M Connolly, David R Chafin filed Critical Integrated Nano Tech Llc
Publication of WO2005019413A2 publication Critical patent/WO2005019413A2/en
Publication of WO2005019413A3 publication Critical patent/WO2005019413A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6825—Nucleic acid detection involving sensors

Abstract

The present invention relates to a device for the detection of a target molecule in an environment. The device includes a detection system having a detection cartridge (303) containing a detection chip where capture probes are attached to two or more electrically separated conductors such that a gap exists between the capture probes on the electrically separated conductors. A sample can be analyzed for the presence of the target molecule by determining whether any target molecules present in the sample bind to the capture probes and electrically connect the conductors. The device includes a cartridge manipulator (302) having a plurality of detection cartridges (303) where an unused individual detection cartridge can be inserted into a support unit (300) for detection of the target molecule in the sample. The present invention also relates to a method for the detection of a biological agent using the device disclosed.
PCT/US2004/018374 2003-06-12 2004-06-09 A low maintenance detector for biological agents WO2005019413A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US47813403P 2003-06-12 2003-06-12
US60/478,134 2003-06-12

Publications (2)

Publication Number Publication Date
WO2005019413A2 WO2005019413A2 (en) 2005-03-03
WO2005019413A3 true WO2005019413A3 (en) 2005-04-07

Family

ID=34215803

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/018374 WO2005019413A2 (en) 2003-06-12 2004-06-09 A low maintenance detector for biological agents

Country Status (1)

Country Link
WO (1) WO2005019413A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6895868B2 (en) * 2017-10-30 2021-06-30 アークレイ株式会社 Analysis equipment

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5519635A (en) * 1993-09-20 1996-05-21 Hitachi Ltd. Apparatus for chemical analysis with detachable analytical units
US5874046A (en) * 1996-10-30 1999-02-23 Raytheon Company Biological warfare agent sensor system employing ruthenium-terminated oligonucleotides complementary to target live agent DNA sequences
US6060023A (en) * 1998-03-31 2000-05-09 Motorola, Inc. Molecular sensing apparatus
US6093370A (en) * 1998-06-11 2000-07-25 Hitachi, Ltd. Polynucleotide separation method and apparatus therefor
US6103479A (en) * 1996-05-30 2000-08-15 Cellomics, Inc. Miniaturized cell array methods and apparatus for cell-based screening
US6399303B1 (en) * 1999-04-07 2002-06-04 Integrated Nano-Technologies, Llc High resolution DNA detection methods and devices

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5519635A (en) * 1993-09-20 1996-05-21 Hitachi Ltd. Apparatus for chemical analysis with detachable analytical units
US6103479A (en) * 1996-05-30 2000-08-15 Cellomics, Inc. Miniaturized cell array methods and apparatus for cell-based screening
US5874046A (en) * 1996-10-30 1999-02-23 Raytheon Company Biological warfare agent sensor system employing ruthenium-terminated oligonucleotides complementary to target live agent DNA sequences
US6060023A (en) * 1998-03-31 2000-05-09 Motorola, Inc. Molecular sensing apparatus
US6093370A (en) * 1998-06-11 2000-07-25 Hitachi, Ltd. Polynucleotide separation method and apparatus therefor
US6399303B1 (en) * 1999-04-07 2002-06-04 Integrated Nano-Technologies, Llc High resolution DNA detection methods and devices

Also Published As

Publication number Publication date
WO2005019413A2 (en) 2005-03-03

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