WO2005023354A1 - Endotherapy catheter - Google Patents
Endotherapy catheter Download PDFInfo
- Publication number
- WO2005023354A1 WO2005023354A1 PCT/GR2004/000045 GR2004000045W WO2005023354A1 WO 2005023354 A1 WO2005023354 A1 WO 2005023354A1 GR 2004000045 W GR2004000045 W GR 2004000045W WO 2005023354 A1 WO2005023354 A1 WO 2005023354A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- catheter
- aspiration
- distal end
- infusion
- membrane
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/28—Peritoneal dialysis ; Other peritoneal treatment, e.g. oxygenation
- A61M1/282—Operational modes
- A61M1/284—Continuous flow peritoneal dialysis [CFPD]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/71—Suction drainage systems
- A61M1/77—Suction-irrigation systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/84—Drainage tubes; Aspiration tips
- A61M1/85—Drainage tubes; Aspiration tips with gas or fluid supply means, e.g. for supplying rinsing fluids or anticoagulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/28—Peritoneal dialysis ; Other peritoneal treatment, e.g. oxygenation
- A61M1/285—Catheters therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/10—General characteristics of the apparatus with powered movement mechanisms
- A61M2205/103—General characteristics of the apparatus with powered movement mechanisms rotating
Definitions
- the proposed invention is a catheter that can be used for infusion of drugs and nutrients with concurrent aspiration of biological material, in human and, or, animal tissue and, or, body cavity, and, or, neoplastic tissue and, or, pathological liquid accumulations in the body.
- catheters which are used for fluid infusion and aspiration in a clinical or preclinical setting.
- distal the tip that is inserted in biological material
- proximal the tip that stays outside
- the common intravenous catheter either aspirates blood samples - usually immediately after it's insertion to the vein - or infuses solutions of drugs and, or, nutrients - usually for many hours or days following insertion.
- catheters can infuse or aspirate large quantities of liquids, but they cannot do it concurrently in order to have a constant exchange of drugs and nutrients with pathological liquid accumulations. That means that during the infusion phase, the tissue increases in volume and this could be dangerous or even fatal in certain cases (for example in an already suffering from oedema brain) .
- catheters with multiple lumen - tubes, which can concurrently infuse and aspirate liquids.
- the microdialysis catheter after it's introduction to a human or animal tissue, is continuously perfused with liquid solutions from a pump connected to its proximal tip.
- the catheter consists of two concentric lumens - tubes, that are covered at their distal tip by a membrane.
- the central lumen - tube is the efferent and the peripheral lumen - tube is the afferent part of the catheter.
- Part of the perfused liquid is infused to the tissue through the catheter's membrane at its distal end, and extracellular tissue fluid is aspirated through the same membrane and the efferent lumen - tube.
- the proposed endotherapy catheter infuses and aspirates, even great quantities of liquids, concurrently, at a wide range of flow rates, without any blockage problems.
- the infusing lumen - tube is appropriately connected to the device that irrigates the surrounding the catheter space, while simultaneously propels with its movement the aspiration through the other tube.
- the endotherapy catheter utilizes the circulating fluid' s shear forces to remove any biological material that blocks the catheter's distal tip.
- the endotherapy catheter has an infusion inner lumen - tube (2) and an aspiration outer lumen - tube (1) .
- the fluid is supplied by an infusion device (14) or any liquid container that has positive pressure, relatively to the pressure of the surrounding the catheter' s tip tissue, while the returning fluid is collected by a negative pressure pump, or any liquid container with negative pressure, relatively to the pressure of the surrounding the catheter's tip tissue.
- the endotherapy catheter has a bifurcation part (16), in order to split the two opposite flows in two different lumens - tubes, as shown in drawing 1.
- the distal end of the outer lumen - tube holds an exchange surface (4), that can be a filter or membrane or grid or mesh cage.
- Fluid which can vary from distilled water to nutrient solutions with drugs, that is supplied through the inner lumen - tube (2), according to arrow B, reaches the distal end of the catheter, where substance exchange occurs between the infused fluid and substances contained in the surrounding tissue's extracellular fluid; the fluid returns to an aspiration device and, or, collection tank and, or, measurement system (15), according to arrow C.
- a fluid jet receiving its supply from the inner lumen - tube (2), is dispersed against the liquid exchange surface's inner wall (4), via the moving - rotating device's ports (8), as shown in drawings 2, 4.
- the jet propels the rotation of the moving - rotating device (3) according to arrow A.
- Drawings 2,3 and 4 depict two of the many possible variations of the same concept.
- the moving - rotating device has a hollow twisted plate shape
- the moving - rotating device resembles a twin helix chain.
- the moving - rotating device (3) holds a port (5) that serves as a fluid supply inlet, but also as a housing for the stator (6), which is the distal end of the inner lumen - tube (2) .
- the stator (6) may hold, circumferentially and on its end, through holes - openings (13), to allow fluid outlet from the inner lumen - tube (2) to the intermediate space (7) between stator and moving rotating device.
- This intermediate space is created since the stator' s (6) outer diameter is slightly smaller than the moving - rotating device's port (5) diameter, and serves as a mass transfer subspace and a friction eliminator, since it follows a slide bearing function principal.
- the moving - rotating device (3) may have an helical shape and hold ports - openings (8), that take fluid from the intermediate space between stator and moving - rotating device (7), and redirect it against the exchange surface walls (4), with a direction angle other than the radial, so that a rotational propulsion is achieved, as shown in drawings 2, 4.
- the angle is selected based on a trade-off between the device's (3) rotation frequency and the shear stress on the exchange surface walls. That is, a rather radial direction biased angle selection would result on fewer rotations per given time but higher shear stresses, while a rather circumferential direction biased angle selection would result on more rotations per given time but lower shear stresses . Therefore, the moving - rotating device (3) not only removes the organic remains that block the exchange surface (4), but is also responsible for its movement - rotation.
- the moving - rotating device (3) may have an overall or particular helical shape with a spin direction such that, due to the jet-induced rotation, its proximal face (17) pushes fluid proximally, forcing its return to the extracorporeal collecting equipment.
- the tip (9) of the moving - rotating device could be such that it supports the device in place inside the outer tube (1) and at the same time allows for relative movement - rotation.
- the lower part of the outer tube may hold a recess (10) , in order to house the tip (9) of the moving - rotating device (3).
- a travel limiter (11) can be present at an appropriate level of the inner tube, to assure operation under all inclinations.
- the inner tube (2) may be centered coaxially to the outer tube (1) to ensure evenness in function.
- one or more centering supports (12) can be placed between the inner and outer tubes, just proximally to the moving - rotating device (3) level.
- the catheter may have an overall flexibility in order not to present resistance during any movement of the implanted tissue relatively to its, relatively stable, exit point, however the distal end has to be fairly rigid, to ensure that the moving - rotating part can work properly. So, the materials are selected appropriately, to offer relative stiffness at the distal end of the inner and outer tube, while more compliant materials may be selected for the rest of the catheter.
- the whole catheter can be rigid.
- the material of the catheter should also be in conformity to the norms and regulations existing for clinical and laboratory catheters, including biocompatibility issues etc.
Abstract
Description
Claims
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/570,403 US20070197959A1 (en) | 2003-09-08 | 2004-09-03 | Endotherapy Catheter |
BRPI0413963-1A BRPI0413963A (en) | 2003-09-08 | 2004-09-03 | endotherapy catheter |
CA002540566A CA2540566A1 (en) | 2003-09-08 | 2004-09-03 | Endotherapy catheter |
JP2006525908A JP2007504874A (en) | 2003-09-08 | 2004-09-03 | Endoscopic catheter |
EP04769058A EP1687054A1 (en) | 2003-09-08 | 2004-09-03 | Endotherapy catheter |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GR20030100371A GR20030100371A (en) | 2003-09-08 | 2003-09-08 | Endotherapy catheter |
GR20030100371 | 2003-09-08 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2005023354A1 true WO2005023354A1 (en) | 2005-03-17 |
WO2005023354B1 WO2005023354B1 (en) | 2005-05-06 |
Family
ID=34259850
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/GR2004/000045 WO2005023354A1 (en) | 2003-09-08 | 2004-09-03 | Endotherapy catheter |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP1687054A1 (en) |
GR (1) | GR20030100371A (en) |
WO (1) | WO2005023354A1 (en) |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1937329A1 (en) * | 2005-09-02 | 2008-07-02 | Estelle Enterprises Limited | Fluid exchange catheter system |
WO2014145052A1 (en) | 2013-03-15 | 2014-09-18 | Health Research, Inc. | Suction device for normal and viscous materials |
WO2014159205A1 (en) * | 2013-03-14 | 2014-10-02 | Bayer Medical Care Inc. | Hydrodynamic eccentrically pivoting catheter |
US9078691B2 (en) | 2009-12-16 | 2015-07-14 | Boston Scientific Limited | Catheter having tapered guide surface |
DE202013012593U1 (en) | 2012-08-10 | 2017-09-18 | Irras Ab | Fluid exchange catheter |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4694832A (en) * | 1982-12-01 | 1987-09-22 | Ungerstedt Carl U | Dialysis probe |
US4755175A (en) * | 1985-07-15 | 1988-07-05 | Leif Nilsson | Catheter |
US6001079A (en) * | 1995-09-05 | 1999-12-14 | Pourchez; Thierry | Multilumen catheter, particularly for hemodialysis |
US6126832A (en) * | 1992-07-30 | 2000-10-03 | Stone; Andrew | Composition for dialysis and shock treatment |
-
2003
- 2003-09-08 GR GR20030100371A patent/GR20030100371A/en unknown
-
2004
- 2004-09-03 EP EP04769058A patent/EP1687054A1/en not_active Withdrawn
- 2004-09-03 WO PCT/GR2004/000045 patent/WO2005023354A1/en active Application Filing
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4694832A (en) * | 1982-12-01 | 1987-09-22 | Ungerstedt Carl U | Dialysis probe |
US4755175A (en) * | 1985-07-15 | 1988-07-05 | Leif Nilsson | Catheter |
US6126832A (en) * | 1992-07-30 | 2000-10-03 | Stone; Andrew | Composition for dialysis and shock treatment |
US6001079A (en) * | 1995-09-05 | 1999-12-14 | Pourchez; Thierry | Multilumen catheter, particularly for hemodialysis |
Cited By (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11123483B2 (en) | 2005-09-02 | 2021-09-21 | Irras Ab | Fluid exchange catheter system |
JP2009506817A (en) * | 2005-09-02 | 2009-02-19 | エステル エンタープライゼズ リミテッド | Fluid replacement catheter system |
EP1937329B1 (en) * | 2005-09-02 | 2011-10-19 | Jaymore Enterprises Limited | Fluid exchange catheter system |
US8398581B2 (en) | 2005-09-02 | 2013-03-19 | Irras Ab | Fluid exchange catheter system |
EP1937329A1 (en) * | 2005-09-02 | 2008-07-02 | Estelle Enterprises Limited | Fluid exchange catheter system |
US9623177B2 (en) | 2005-09-02 | 2017-04-18 | Irras Ab | Fluid exchange catheter system |
US10293105B2 (en) | 2005-09-02 | 2019-05-21 | Irras Ab | Fluid exchange catheter system |
US9078691B2 (en) | 2009-12-16 | 2015-07-14 | Boston Scientific Limited | Catheter having tapered guide surface |
US9901361B2 (en) | 2009-12-16 | 2018-02-27 | Boston Scientific Limited | Catheter having tapered guide surface |
DE202013012593U1 (en) | 2012-08-10 | 2017-09-18 | Irras Ab | Fluid exchange catheter |
WO2014159205A1 (en) * | 2013-03-14 | 2014-10-02 | Bayer Medical Care Inc. | Hydrodynamic eccentrically pivoting catheter |
US9737328B2 (en) | 2013-03-14 | 2017-08-22 | Boston Scientific Limited | Hydrodynamic eccentrically pivoting catheter |
US10582946B2 (en) | 2013-03-14 | 2020-03-10 | Boston Scientific Limited | Hydrodynamic eccentrically pivoting catheter |
WO2014145052A1 (en) | 2013-03-15 | 2014-09-18 | Health Research, Inc. | Suction device for normal and viscous materials |
US10286125B2 (en) | 2013-03-15 | 2019-05-14 | Health Research, Inc. | Suction device for normal and viscous materials |
EP2967517A4 (en) * | 2013-03-15 | 2016-10-19 | Health Research Inc | Suction device for normal and viscous materials |
Also Published As
Publication number | Publication date |
---|---|
WO2005023354B1 (en) | 2005-05-06 |
GR20030100371A (en) | 2005-05-18 |
EP1687054A1 (en) | 2006-08-09 |
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