WO2005032512A3 - Capsules of multilayered neutral polymer films associated by hydrogen bonding - Google Patents

Capsules of multilayered neutral polymer films associated by hydrogen bonding Download PDF

Info

Publication number
WO2005032512A3
WO2005032512A3 PCT/US2004/032491 US2004032491W WO2005032512A3 WO 2005032512 A3 WO2005032512 A3 WO 2005032512A3 US 2004032491 W US2004032491 W US 2004032491W WO 2005032512 A3 WO2005032512 A3 WO 2005032512A3
Authority
WO
WIPO (PCT)
Prior art keywords
capsules
hydrogen bonding
polymer films
neutral polymer
films associated
Prior art date
Application number
PCT/US2004/032491
Other languages
French (fr)
Other versions
WO2005032512A2 (en
Inventor
Svetlana A Sukhishvili
Veronika Kozlovskaya
Eugenia Kharlampieva
Original Assignee
Trustees Stevens Inst Tech
Svetlana A Sukhishvili
Veronika Kozlovskaya
Eugenia Kharlampieva
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Trustees Stevens Inst Tech, Svetlana A Sukhishvili, Veronika Kozlovskaya, Eugenia Kharlampieva filed Critical Trustees Stevens Inst Tech
Priority to CA002541974A priority Critical patent/CA2541974A1/en
Priority to JP2006534181A priority patent/JP2007514518A/en
Priority to EP04789485A priority patent/EP1691791A2/en
Publication of WO2005032512A2 publication Critical patent/WO2005032512A2/en
Publication of WO2005032512A3 publication Critical patent/WO2005032512A3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089Processes

Abstract

Micro-, and nano-scale capsules comprising neutral (uncharged) polymeric layers, layers associated by hydrogen bonding and methods for making such capsules. The capsules of the invention are layered upon a core particle using a layer-by layer-technique. The capsule walls of the capsules of the invention give a tailored response to external stimuli.
PCT/US2004/032491 2003-10-02 2004-09-30 Capsules of multilayered neutral polymer films associated by hydrogen bonding WO2005032512A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
CA002541974A CA2541974A1 (en) 2003-10-02 2004-09-30 Capsules of multilayered neutral polymer films associated by hydrogen bonding
JP2006534181A JP2007514518A (en) 2003-10-02 2004-09-30 Capsule of multilayer neutral polymer film bonded by hydrogen bonding
EP04789485A EP1691791A2 (en) 2003-10-02 2004-09-30 Capsules of multilayered neutral polymer films associated by hydrogen bonding

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US50875403P 2003-10-02 2003-10-02
US60/508,754 2003-10-02
US51044903P 2003-10-10 2003-10-10
US60/510,449 2003-10-10

Publications (2)

Publication Number Publication Date
WO2005032512A2 WO2005032512A2 (en) 2005-04-14
WO2005032512A3 true WO2005032512A3 (en) 2006-03-30

Family

ID=34426066

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/032491 WO2005032512A2 (en) 2003-10-02 2004-09-30 Capsules of multilayered neutral polymer films associated by hydrogen bonding

Country Status (5)

Country Link
US (1) US20050163714A1 (en)
EP (1) EP1691791A2 (en)
JP (1) JP2007514518A (en)
CA (1) CA2541974A1 (en)
WO (1) WO2005032512A2 (en)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7101575B2 (en) 1998-03-19 2006-09-05 Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. Production of nanocapsules and microcapsules by layer-wise polyelectrolyte self-assembly
US11207805B2 (en) 2001-10-12 2021-12-28 Aquestive Therapeutics, Inc. Process for manufacturing a resulting pharmaceutical film
US8603514B2 (en) 2002-04-11 2013-12-10 Monosol Rx, Llc Uniform films for rapid dissolve dosage form incorporating taste-masking compositions
US10285910B2 (en) 2001-10-12 2019-05-14 Aquestive Therapeutics, Inc. Sublingual and buccal film compositions
US20190328679A1 (en) 2001-10-12 2019-10-31 Aquestive Therapeutics, Inc. Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions
US7357891B2 (en) 2001-10-12 2008-04-15 Monosol Rx, Llc Process for making an ingestible film
US20110033542A1 (en) 2009-08-07 2011-02-10 Monosol Rx, Llc Sublingual and buccal film compositions
US8900497B2 (en) 2001-10-12 2014-12-02 Monosol Rx, Llc Process for making a film having a substantially uniform distribution of components
US8765167B2 (en) 2001-10-12 2014-07-01 Monosol Rx, Llc Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions
US8663687B2 (en) * 2001-10-12 2014-03-04 Monosol Rx, Llc Film compositions for delivery of actives
US20070281003A1 (en) 2001-10-12 2007-12-06 Fuisz Richard C Polymer-Based Films and Drug Delivery Systems Made Therefrom
US8900498B2 (en) 2001-10-12 2014-12-02 Monosol Rx, Llc Process for manufacturing a resulting multi-layer pharmaceutical film
US20040137039A1 (en) * 2002-07-22 2004-07-15 Trustees Of Stevens Institute Of Technology Methods for controlled release of molecules from layered polymer films
DE102004013637A1 (en) 2004-03-19 2005-10-13 Capsulution Nanoscience Ag Process for the preparation of CS particles and microcapsules using porous templates as well as CS particles and microcapsules
AU2005337071B2 (en) * 2005-10-05 2011-11-24 Sca Hygiene Products Ab Absorbent article comprising a thin film including an active agent
JP2009509700A (en) * 2005-10-05 2009-03-12 エスセーアー・ハイジーン・プロダクツ・アーベー Absorbent article comprising a hydrophilic region and a hydrophobic region
CN103054738A (en) * 2006-02-14 2013-04-24 宝洁公司 Personal care compositions comprising responsive particles
EP2082075B1 (en) 2006-09-08 2017-05-17 Massachusetts Institute of Technology Automated layer by layer spray technology
US20080182056A1 (en) * 2007-01-30 2008-07-31 Eric Bakker Hollow Microsphere Particles
EP2164857B1 (en) * 2007-06-22 2016-10-05 The Trustees Of The University Of Pennsylvania Fluorescent labeling of transfer rna and study of protein synthesis
US7931729B2 (en) * 2007-08-14 2011-04-26 Cellulosetek, Llc Controlled release fertilizers and methods of manufacture
CN101703490B (en) * 2009-11-13 2013-08-07 杭州师范大学 Polysaccharide/inorganic nanoparticles hybrid micron-nano medicine-carrying capsule
US9149959B2 (en) 2010-10-22 2015-10-06 Monosol Rx, Llc Manufacturing of small film strips
GB201102148D0 (en) 2011-02-08 2011-03-23 Ucl Business Plc Layered bodies, compositions containing them and processes for producing them
WO2013006683A2 (en) * 2011-07-05 2013-01-10 The Uab Research Foundation Bio-mimetic ultrathin hydrogel coatings for pancreatic islet transplantation
WO2013103514A1 (en) 2012-01-04 2013-07-11 The Trustees Of The Stevens Institute Of Technology Clay-containing thin films as carriers of absorbed molecules
JP6008177B2 (en) * 2012-08-15 2016-10-19 株式会社伏見製薬所 Method for producing molecular recognition polymer
TWI605870B (en) * 2012-10-25 2017-11-21 奇華頓公司 Process
TWI646978B (en) * 2012-10-25 2019-01-11 Givaudan Sa capsule
CA3022840A1 (en) 2016-05-05 2017-11-09 Aquestive Therapeutics, Inc. Enhanced delivery epinephrine compositions
US11273131B2 (en) 2016-05-05 2022-03-15 Aquestive Therapeutics, Inc. Pharmaceutical compositions with enhanced permeation
CA3035769A1 (en) * 2016-09-02 2018-03-08 Harvey M. Goertz Particulate compositions and methods of use
US11541105B2 (en) 2018-06-01 2023-01-03 The Research Foundation For The State University Of New York Compositions and methods for disrupting biofilm formation and maintenance
JP7399860B2 (en) 2018-08-10 2023-12-18 三洋化成工業株式会社 coated bioactive material
JP7419083B2 (en) 2019-11-27 2024-01-22 三洋化成工業株式会社 Covered agricultural, forestry, and horticultural granular chemicals

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999047252A2 (en) * 1998-03-19 1999-09-23 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Production of nanocapsules and microcapsules by layer-wise polyelectrolyte self-assembly
US6511749B1 (en) * 1987-05-01 2003-01-28 Brown University Research Foundation Preparation of multiwall polymeric microcapsules from hydrophilic polymers
WO2003035278A1 (en) * 2001-10-25 2003-05-01 Massachusetts Institute Of Technology Method of depositing polyelectrolyte multilayers and articles coated thereby

Family Cites Families (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4286064A (en) * 1979-11-05 1981-08-25 Riker Laboratories, Inc. Process for isolating active debriding agent from bromelain
NZ203337A (en) * 1982-02-26 1986-02-21 M S M Lefebvre Immobilised inorganic counter diffusion barriers and their applications
DE3780700T2 (en) * 1986-05-14 1993-02-04 Takiron Co ADHESIVE FOR PERCUTANEOUS ADMINISTRATION.
US4684558A (en) * 1986-06-30 1987-08-04 Nepera Inc. Adhesive polyethylene oxide hydrogel sheet and its production
US5593395A (en) * 1987-08-07 1997-01-14 Martz; Joel D. Vapor permeable dressing
US5143071A (en) * 1989-03-30 1992-09-01 Nepera, Inc. Non-stringy adhesive hydrophilic gels
US5171264A (en) * 1990-02-28 1992-12-15 Massachusetts Institute Of Technology Immobilized polyethylene oxide star molecules for bioapplications
US5275838A (en) * 1990-02-28 1994-01-04 Massachusetts Institute Of Technology Immobilized polyethylene oxide star molecules for bioapplications
IL97142A0 (en) * 1990-03-02 1992-05-25 Duphar Int Res Wound dressing and its preparation
US5168037A (en) * 1990-08-02 1992-12-01 Phyllis Entis Method for the preparation of a labelled virus without the inactivation of viral binding sites and method of assay utilizing said labelled virus
US5626863A (en) * 1992-02-28 1997-05-06 Board Of Regents, The University Of Texas System Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers
ES2153378T3 (en) * 1992-02-28 2001-03-01 Univ Texas PHOTOPOLIMERIZABLE BIODEGRADABLE HYDROGELS AS FABRIC CONTACT MATERIALS AND CONTROLLED DISCHARGE CARRIER.
US5756117A (en) * 1992-04-08 1998-05-26 International Medical Asscociates, Inc. Multidose transdermal drug delivery system
DE69323975T2 (en) * 1992-12-15 1999-08-19 Johnson & Johnson Consumer Hydrogel laminate, wound dressings and composite materials and processes for their manufacture
US5674275A (en) * 1994-04-06 1997-10-07 Graphic Controls Corporation Polyacrylate and polymethacrylate ester based hydrogel adhesives
JP3576608B2 (en) * 1994-11-15 2004-10-13 日東電工株式会社 Patches and patch preparations
US5700559A (en) * 1994-12-16 1997-12-23 Advanced Surface Technology Durable hydrophilic surface coatings
US5712346A (en) * 1995-02-14 1998-01-27 Avery Dennison Corporation Acrylic emulsion coatings
US5786439A (en) * 1996-10-24 1998-07-28 Minimed Inc. Hydrophilic, swellable coatings for biosensors
US5837313A (en) * 1995-04-19 1998-11-17 Schneider (Usa) Inc Drug release stent coating process
US6509098B1 (en) * 1995-11-17 2003-01-21 Massachusetts Institute Of Technology Poly(ethylene oxide) coated surfaces
US5846214A (en) * 1996-03-29 1998-12-08 Nichiban Company Limited PVA hydrogel, hydrogel laminate using the same and hydrogel wound-dressing material using the same
DE69737590T2 (en) * 1996-08-07 2007-12-20 Nippon Shokubai Co. Ltd. Water-absorbing product and process for its preparation
US6068053A (en) * 1996-11-07 2000-05-30 Baker Hughes, Ltd. Fluid separation and reinjection systems
US5879697A (en) * 1997-04-30 1999-03-09 Schneider Usa Inc Drug-releasing coatings for medical devices
US5840329A (en) * 1997-05-15 1998-11-24 Bioadvances Llc Pulsatile drug delivery system
US6444744B1 (en) * 1998-03-11 2002-09-03 Nippon Shokubai Co., Ltd. Hydrophilic resin, absorbent article, and acrylic acid for polymerization
US6103785A (en) * 1998-03-26 2000-08-15 Nippon Shokubai Co., Ltd. Water-absorbing agent and its production process and use
US6849702B2 (en) * 1999-02-26 2005-02-01 Robert W. Callahan Polymer matrix material
GB9909349D0 (en) * 1999-04-23 1999-06-16 First Water Ltd Process
US6689165B2 (en) * 2000-03-31 2004-02-10 Board Of Supervisors Of Louisana State University And Agricultural And Mechanical College Surface modifications for enhanced epithelialization
US20020037383A1 (en) * 2000-04-14 2002-03-28 Spillman William B. Self-assembled thin film coating to enhance the biocompatibility of materials
WO2001079849A2 (en) * 2000-04-17 2001-10-25 Trans Tech Pharma Protein expression system arrays and use in biological screening
US6740409B1 (en) * 2000-11-15 2004-05-25 Board Of Trustees Of University Of Illinois Polymer films
US20030082225A1 (en) * 2001-10-19 2003-05-01 Mason Paul Arthur Sterile, breathable patch for treating wound pain
US6617372B2 (en) * 2001-10-23 2003-09-09 Isp Investments Inc. Process of making polymeric hydrogel products
US20030215626A1 (en) * 2002-03-22 2003-11-20 Hiller Jeri?Apos;Ann Nanoporous coatings
US6770729B2 (en) * 2002-09-30 2004-08-03 Medtronic Minimed, Inc. Polymer compositions containing bioactive agents and methods for their use
US7323289B2 (en) * 2002-10-08 2008-01-29 Brewer Science Inc. Bottom anti-reflective coatings derived from small core molecules with multiple epoxy moieties

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6511749B1 (en) * 1987-05-01 2003-01-28 Brown University Research Foundation Preparation of multiwall polymeric microcapsules from hydrophilic polymers
WO1999047252A2 (en) * 1998-03-19 1999-09-23 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Production of nanocapsules and microcapsules by layer-wise polyelectrolyte self-assembly
WO2003035278A1 (en) * 2001-10-25 2003-05-01 Massachusetts Institute Of Technology Method of depositing polyelectrolyte multilayers and articles coated thereby

Also Published As

Publication number Publication date
WO2005032512A2 (en) 2005-04-14
US20050163714A1 (en) 2005-07-28
JP2007514518A (en) 2007-06-07
CA2541974A1 (en) 2005-04-14
EP1691791A2 (en) 2006-08-23

Similar Documents

Publication Publication Date Title
WO2005032512A3 (en) Capsules of multilayered neutral polymer films associated by hydrogen bonding
WO2007107574A3 (en) Encapsulated nanoparticles, especially those having a core/shell structure
WO2010054715A3 (en) Adsorptive structures and the use thereof
WO2011078492A3 (en) Multifunctional resin composite and moulded articles employing the same
WO2005014216A3 (en) Methods for manufacture of multilayered multifunctional truss structures and related structures there from
WO2007028937A3 (en) Olfactory patch
WO2004072413A3 (en) Inflatable rigidizable boom
WO2007114895A3 (en) Production of three-dimensional objects by use of electromagnetic radiation
WO2008082698A3 (en) Medical devices and methods of making the same
DE60319694D1 (en) PACKAGING LAMINATE, METHOD FOR THE PRODUCTION THEREOF, AND PACKAGING CONTAINER PRODUCED FROM THE PACKAGING LAMINATE
ATE390278T1 (en) PACKAGING LAMINATE, METHOD FOR THE PRODUCTION THEREOF AND PACKAGING CONTAINER PRODUCED FROM THE PACKAGING LAMINATE
WO2006099176A3 (en) 3-d interconnected multi-layer microstructure of thermoplastic materials
WO2006125620A3 (en) Cores and microcapsules suitable for parenteral administration as well as process for their manufacture
HK1090042A1 (en) Substituted 4-phenyltetrahydroisoquinolines, method for the production thereof, the of the same as medicaments, and medicament containing such compounds
WO2006083765A3 (en) Transverse-direction, elastomeric, breathable film
ATE538819T1 (en) MEDICAL DEVICES AND METHOD FOR THE PRODUCTION THEREOF
EP2172425A4 (en) Organized clay, process for producing the same, and resin composite containing organized clay
WO2010045911A3 (en) Inlay for a security and/or value document and method for producing the same
WO2005030825A3 (en) Two-component composition for producing polyurethane gel coats for epoxy-resin and vinyl-ester resin composite materials
WO2005098390A3 (en) Container for accommodating media, and method for the production and verification of the leakproofness of said container
WO2002087873A3 (en) Multilayer polymeric films
JP5914306B2 (en) Vessel with hydrogen generation function and hydrogen addition method
WO2010112912A3 (en) Composite absorbent materials and methods for their production
MX2009005707A (en) Method for the production of a multilayer laminate, and multilayer laminate.
PL1728624T3 (en) Multilayered films with optical effects and process for their manufacture

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BW BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE EG ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NA NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SY TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GM KE LS MW MZ NA SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LU MC NL PL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
WWE Wipo information: entry into national phase

Ref document number: 2004789485

Country of ref document: EP

Ref document number: 2006534181

Country of ref document: JP

WWE Wipo information: entry into national phase

Ref document number: 2541974

Country of ref document: CA

WWP Wipo information: published in national office

Ref document number: 2004789485

Country of ref document: EP