WO2005035552A3 - Transducing combinatorial peptide library - Google Patents

Transducing combinatorial peptide library Download PDF

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Publication number
WO2005035552A3
WO2005035552A3 PCT/US2004/033278 US2004033278W WO2005035552A3 WO 2005035552 A3 WO2005035552 A3 WO 2005035552A3 US 2004033278 W US2004033278 W US 2004033278W WO 2005035552 A3 WO2005035552 A3 WO 2005035552A3
Authority
WO
WIPO (PCT)
Prior art keywords
transducing
peptide library
bio
combinatorial peptide
molecules
Prior art date
Application number
PCT/US2004/033278
Other languages
French (fr)
Other versions
WO2005035552A2 (en
Inventor
Charles A Nicolette
Original Assignee
Genzyme Corp
Charles A Nicolette
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genzyme Corp, Charles A Nicolette filed Critical Genzyme Corp
Publication of WO2005035552A2 publication Critical patent/WO2005035552A2/en
Publication of WO2005035552A3 publication Critical patent/WO2005035552A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/047—Simultaneous synthesis of different peptide species; Peptide libraries

Abstract

This invention provides methods for isolating bio-active molecules from complex, rationally designed peptide libraries with a reduction in assay time and increase in throughput. The molecules have the ability to facilitate transport across biological membranes. The methods also identify bio-active peptides of therapeutic value such as vaccines in treating cancers, viral diseases, and autoimmune diseases, as well as to identify useful clinical diagnostic reagents.
PCT/US2004/033278 2003-10-07 2004-10-06 Transducing combinatorial peptide library WO2005035552A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US50960103P 2003-10-07 2003-10-07
US60/509,601 2003-10-07

Publications (2)

Publication Number Publication Date
WO2005035552A2 WO2005035552A2 (en) 2005-04-21
WO2005035552A3 true WO2005035552A3 (en) 2005-09-01

Family

ID=34434995

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/033278 WO2005035552A2 (en) 2003-10-07 2004-10-06 Transducing combinatorial peptide library

Country Status (1)

Country Link
WO (1) WO2005035552A2 (en)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5846841A (en) * 1994-05-20 1998-12-08 Selectide Corporation Motif Libraries
US5858670A (en) * 1990-07-02 1999-01-12 The Arizona Board Of Regents Bio-oligomer libraries and a method of use thereof
US6338945B1 (en) * 1996-03-20 2002-01-15 Genzyme Corporation Method for identifying cytotoxic T-cell epitopes

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5858670A (en) * 1990-07-02 1999-01-12 The Arizona Board Of Regents Bio-oligomer libraries and a method of use thereof
US5846841A (en) * 1994-05-20 1998-12-08 Selectide Corporation Motif Libraries
US6338945B1 (en) * 1996-03-20 2002-01-15 Genzyme Corporation Method for identifying cytotoxic T-cell epitopes

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DOOLEY C.T. ET AL.: "An all d-amino acid opioid peptide with central analgesic", SCIENCE., vol. 266, December 1994 (1994-12-01), pages 2019 - 2022, XP002955242 *
OHLMEYER M. ET AL.: "Complex synthetic chemical libraries indexed with molecular tags.", PNAS USA, vol. 90, December 1993 (1993-12-01), pages 10922 - 10926, XP000829535 *

Also Published As

Publication number Publication date
WO2005035552A2 (en) 2005-04-21

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