WO2005053613A3 - Combinations for the treatment of fungal infections - Google Patents

Combinations for the treatment of fungal infections Download PDF

Info

Publication number
WO2005053613A3
WO2005053613A3 PCT/US2004/039600 US2004039600W WO2005053613A3 WO 2005053613 A3 WO2005053613 A3 WO 2005053613A3 US 2004039600 W US2004039600 W US 2004039600W WO 2005053613 A3 WO2005053613 A3 WO 2005053613A3
Authority
WO
WIPO (PCT)
Prior art keywords
combinations
treatment
fungal infections
patient
fungal infection
Prior art date
Application number
PCT/US2004/039600
Other languages
French (fr)
Other versions
WO2005053613A2 (en
Inventor
George N Serbedzija
Lisa M Johansen
Benjamin A Auspitz
Original Assignee
Combinatorx Inc
George N Serbedzija
Lisa M Johansen
Benjamin A Auspitz
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Combinatorx Inc, George N Serbedzija, Lisa M Johansen, Benjamin A Auspitz filed Critical Combinatorx Inc
Publication of WO2005053613A2 publication Critical patent/WO2005053613A2/en
Publication of WO2005053613A3 publication Critical patent/WO2005053613A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
    • A61K31/37—Coumarins, e.g. psoralen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/32—Manganese; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/48—Medical, disinfecting agents, disinfecting, antibacterial, germicidal or antimicrobial compositions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

The invention features a method for treating a fungal infection in a patient in need thereof by administering to the patient an antifungal agent and a manganese compound simultaneously or within 14 days of each other in amounts sufficient to treat the fungal infection.
PCT/US2004/039600 2003-11-26 2004-11-24 Combinations for the treatment of fungal infections WO2005053613A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US52562503P 2003-11-26 2003-11-26
US60/525,625 2003-11-26

Publications (2)

Publication Number Publication Date
WO2005053613A2 WO2005053613A2 (en) 2005-06-16
WO2005053613A3 true WO2005053613A3 (en) 2005-08-18

Family

ID=34652367

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/039600 WO2005053613A2 (en) 2003-11-26 2004-11-24 Combinations for the treatment of fungal infections

Country Status (1)

Country Link
WO (1) WO2005053613A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2011240749B2 (en) 2010-04-13 2016-12-08 Kci Licensing, Inc. Compositions with reactive ingredients, and wound dressings, apparatuses, and methods
WO2017216722A2 (en) * 2016-06-13 2017-12-21 Vyome Biosciences Pvt. Ltd. Synergistic antifungal compositions and methods thereof
JP2019521993A (en) * 2016-06-13 2019-08-08 ビオーム セラピューティクス リミテッド Synergistic antifungal composition and method thereof
CN110753698A (en) * 2017-01-31 2020-02-04 奇达拉治疗公司 Methods for treating fungal infections

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5866168A (en) * 1995-10-26 1999-02-02 Societe L'oreal S.A. Dermatological/pharmaceutical compositions comprising lanthanide, manganese, tin, zinc, yttrium, cobalt, barium and/or strontium salts as substance P antagonists
US5993787A (en) * 1996-09-13 1999-11-30 Johnson & Johnson Consumer Products, Inc. Composition base for topical therapeutic and cosmetic preparations
US6124352A (en) * 1992-03-04 2000-09-26 Jemlan, Llc Antifungal agents
US6153208A (en) * 1997-09-12 2000-11-28 The Procter & Gamble Company Cleansing and conditioning article for skin or hair
US6645531B1 (en) * 2000-01-06 2003-11-11 Marantech Holding Llc Multivalent electron active compositions and methods of making and using same
WO2003092617A2 (en) * 2002-05-03 2003-11-13 Combinatorx, Incorporated Combinations for the treatment of inflammatory skin disorders
US20040157837A1 (en) * 2002-11-07 2004-08-12 Serbedzija George N. Combinations for the treatment of fungal infections

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6124352A (en) * 1992-03-04 2000-09-26 Jemlan, Llc Antifungal agents
US5866168A (en) * 1995-10-26 1999-02-02 Societe L'oreal S.A. Dermatological/pharmaceutical compositions comprising lanthanide, manganese, tin, zinc, yttrium, cobalt, barium and/or strontium salts as substance P antagonists
US5993787A (en) * 1996-09-13 1999-11-30 Johnson & Johnson Consumer Products, Inc. Composition base for topical therapeutic and cosmetic preparations
US6153208A (en) * 1997-09-12 2000-11-28 The Procter & Gamble Company Cleansing and conditioning article for skin or hair
US6645531B1 (en) * 2000-01-06 2003-11-11 Marantech Holding Llc Multivalent electron active compositions and methods of making and using same
WO2003092617A2 (en) * 2002-05-03 2003-11-13 Combinatorx, Incorporated Combinations for the treatment of inflammatory skin disorders
US20040157837A1 (en) * 2002-11-07 2004-08-12 Serbedzija George N. Combinations for the treatment of fungal infections

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
GENNARO A. ET AL.: "Remington: The science and practice of Pharmacy", 1985, EASTON: MACK PUBLISHING COMPANY, pages: 1772 - 1777 *

Also Published As

Publication number Publication date
WO2005053613A2 (en) 2005-06-16

Similar Documents

Publication Publication Date Title
WO2005096990A3 (en) Novel modification of medical prostheses
BR0317564A (en) Compounds, compositions and methods for treating bacterial or fungal diseases
WO2004006906A3 (en) Methods for the treatment of neoplasms
WO2005027842A8 (en) Combinations of drugs for the treatment of neoplasms
WO2002056912A3 (en) Pharmaceutical combination for the treatment of cancer containing a 4-quinazolineamine and another anti-neoplastic agent
WO2004006842A3 (en) Combinations of drugs for the treatment of neoplasms
WO2006006172A3 (en) Use of anti-amyloid agents for treating and typing pathogen infections
WO1999052515A3 (en) Use of organophosphoric compounds for the therapeutic and preventative treatment of infections
WO2004056307A3 (en) Disease treatment via antimicrobial peptide inhibitors
WO2005046618A3 (en) Methods of treating eczema
WO2005034883A3 (en) A method of healing skin wounds in mammals and a composition therefor
WO2006034001A3 (en) Methods of treating hiv infection
WO2005046661A3 (en) Use of nitric oxide donors for the treatment of drug addiction
WO2004096216A3 (en) Use of a topical medicament comprising riluzole
CA2530474A1 (en) Remedy for sarcoidosis and method of treating the same
WO2004110151A8 (en) Treatment of cancer with active vitamin d compounds in combination with radiotherapeutic agents and treatments
WO2004046196A3 (en) Compositions and methods for treating bacterial infections with protein-dalbavancin complexes
WO2005011572A3 (en) Combination of drugs for the treatment of neoplasms
WO2003101382A3 (en) Compounds useful in the treatment of anthrax and inhibiting lethal factor
WO2004073615A8 (en) Deazaflavin compounds and methods of use thereof
WO2004007676A3 (en) Combination therapy for the treatment of neoplasms
WO2004006849A3 (en) Combinations of drugs for the treatment of neoplasms
WO2005053613A3 (en) Combinations for the treatment of fungal infections
WO2002055022A3 (en) Active metabolite of antifungal compound
WO2005080549A3 (en) Trioxacarcins and their use against infections

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BW BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE EG ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NA NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SY TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GM KE LS MW MZ NA SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LU MC NL PL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
NENP Non-entry into the national phase

Ref country code: DE

WWW Wipo information: withdrawn in national office

Country of ref document: DE

32PN Ep: public notification in the ep bulletin as address of the adressee cannot be established

Free format text: NOTHING OF LOSS RIGHTS PURSUANT TO RULE 69(1) EPC(EPO COMMUNICATIONS =>FORMS 1205A DATED 02.08.2006 AND 11.09.2006)

32PN Ep: public notification in the ep bulletin as address of the adressee cannot be established

Free format text: NOTING OF LOSS OF RIGHTS PURSUANT TO RULE 69(1) EPC

122 Ep: pct application non-entry in european phase