WO2005055886A1 - 骨補填材 - Google Patents
骨補填材 Download PDFInfo
- Publication number
- WO2005055886A1 WO2005055886A1 PCT/JP2004/018359 JP2004018359W WO2005055886A1 WO 2005055886 A1 WO2005055886 A1 WO 2005055886A1 JP 2004018359 W JP2004018359 W JP 2004018359W WO 2005055886 A1 WO2005055886 A1 WO 2005055886A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- bone
- replacement material
- bone replacement
- material according
- filling
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/02—Inorganic materials
- A61L27/12—Phosphorus-containing materials, e.g. apatite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/28—Bones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/00234—Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/06—Measuring instruments not otherwise provided for
- A61B2090/062—Measuring instruments not otherwise provided for penetration depth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/46—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor
- A61F2/4601—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for introducing bone substitute, for implanting bone graft implants or for compacting them in the bone cavity
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/46—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor
- A61F2/4603—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/28—Bones
- A61F2002/2835—Bone graft implants for filling a bony defect or an endoprosthesis cavity, e.g. by synthetic material or biological material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30108—Shapes
- A61F2002/3011—Cross-sections or two-dimensional shapes
- A61F2002/30138—Convex polygonal shapes
- A61F2002/30153—Convex polygonal shapes rectangular
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30108—Shapes
- A61F2002/3011—Cross-sections or two-dimensional shapes
- A61F2002/30138—Convex polygonal shapes
- A61F2002/30156—Convex polygonal shapes triangular
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30108—Shapes
- A61F2002/3011—Cross-sections or two-dimensional shapes
- A61F2002/30138—Convex polygonal shapes
- A61F2002/30158—Convex polygonal shapes trapezoidal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30108—Shapes
- A61F2002/30199—Three-dimensional shapes
- A61F2002/30224—Three-dimensional shapes cylindrical
- A61F2002/3023—Three-dimensional shapes cylindrical wedge-shaped cylinders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30108—Shapes
- A61F2002/30199—Three-dimensional shapes
- A61F2002/30261—Three-dimensional shapes parallelepipedal
- A61F2002/30266—Three-dimensional shapes parallelepipedal wedge-shaped parallelepipeds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30108—Shapes
- A61F2002/30199—Three-dimensional shapes
- A61F2002/3028—Three-dimensional shapes polyhedral different from parallelepipedal and pyramidal
- A61F2002/30281—Three-dimensional shapes polyhedral different from parallelepipedal and pyramidal wedge-shaped
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30316—The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
- A61F2002/30535—Special structural features of bone or joint prostheses not otherwise provided for
- A61F2002/30617—Visible markings for adjusting, locating or measuring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/46—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor
- A61F2002/4635—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor using minimally invasive surgery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/46—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor
- A61F2/4657—Measuring instruments used for implanting artificial joints
- A61F2002/4662—Measuring instruments used for implanting artificial joints for measuring penetration depth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2230/0002—Two-dimensional shapes, e.g. cross-sections
- A61F2230/0017—Angular shapes
- A61F2230/0019—Angular shapes rectangular
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2230/0002—Two-dimensional shapes, e.g. cross-sections
- A61F2230/0017—Angular shapes
- A61F2230/0023—Angular shapes triangular
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2230/0002—Two-dimensional shapes, e.g. cross-sections
- A61F2230/0017—Angular shapes
- A61F2230/0026—Angular shapes trapezoidal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2230/0063—Three-dimensional shapes
- A61F2230/0069—Three-dimensional shapes cylindrical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2230/0063—Three-dimensional shapes
- A61F2230/0082—Three-dimensional shapes parallelepipedal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2230/0063—Three-dimensional shapes
- A61F2230/0086—Pyramidal, tetrahedral, or wedge-shaped
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
- A61F2250/0096—Markers and sensors for detecting a position or changes of a position of an implant, e.g. RF sensors, ultrasound markers
- A61F2250/0097—Visible markings, e.g. indicia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
- A61F2310/00005—The prosthesis being constructed from a particular material
- A61F2310/00179—Ceramics or ceramic-like structures
- A61F2310/00293—Ceramics or ceramic-like structures containing a phosphorus-containing compound, e.g. apatite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants
Definitions
- the present invention relates to a bone substitute.
- a crushed vertebral body is returned to almost its original shape, that is, a reduction operation is performed on the vertebral body, and then a cavity (bone) formed in the vertebral body by a caulking operation (A defect part) is filled with a bone replacement material.
- a bone substitute pushes the fragile cancellous bone, eventually reinforcing the inside of the vertebral body.
- a hole formed in a vertebral body is also directly filled in a crushed vertebral body with a granular bone filling material (see, for example, JP-A-2003-169811). ;).
- a bone filling material that satisfies at least one of the conditions of Pa or more.
- the operation for filling the bone defect with the bone filling material can be performed more smoothly, reliably, and safely, and the filling rate of the bone defect can be made particularly high. Can be exhibited for a longer period of time.
- the filling rate of the bone defect can be particularly increased, and the effect of the operation can be exhibited for a longer period.
- the operation for filling the bone defect with the bone filling material can be performed more smoothly, reliably, and safely, and the filling rate of the bone defect can be made particularly high. Can be exhibited for a longer period of time.
- the filling rate of the bone defect can be particularly increased, and the effect of the operation can be exhibited for a longer period.
- the bone replacement material according to the above (5) which has a shape obtained by removing a part of the triangular prism.
- the operation for filling the bone defect with the bone filling material can be performed more smoothly, reliably, and safely, and the filling rate of the bone defect can be made particularly high. Can be exhibited for a longer period of time.
- the filling rate of the bone defect can be particularly increased, and the effect of the operation can be exhibited for a longer period.
- the operation for filling the bone defect with the bone filling material can be performed more smoothly, reliably, and safely, and the filling rate of the bone defect can be made particularly high. Can be exhibited for a longer period of time.
- the operation for filling the bone defect with the bone filling material can be performed more smoothly, reliably, and safely, and the filling rate of the bone defect can be made particularly high. Can be exhibited for a longer period of time.
- the operation for filling the bone defect with the bone filling material can be performed more smoothly, reliably, and safely, and the filling rate of the bone defect can be made particularly high. Can be exhibited for a longer period of time.
- the operation for filling the bone defect with the bone filling material can be performed more smoothly, reliably, and safely, and the filling rate of the bone defect can be made particularly high. Can be exhibited for a longer period of time.
- the operation of filling the bone defect with the bone filling material can be performed more smoothly, reliably, and safely, and the filling rate of the bone defect with a particularly high rate can be achieved.
- the fruit can be exhibited over a longer period.
- the operability in filling the bone defect with the bone replacement material can be sufficiently ensured, and the filling rate of the bone defect can be particularly increased, and the effect of the operation can be extended over a longer period. Can be demonstrated.
- the filling rate of the bone defect can be particularly increased, and the effect of the operation can be exhibited for a longer period.
- the filling rate of the bone defect can be particularly increased, and the effect of the operation can be exhibited for a longer period.
- the bone replacement material according to the above (1) which is mainly composed of ceramics.
- the bone defect of at least one bone selected from the group consisting of a vertebral body, iliac bone, scapula, humerus, ulna, radius, femur, tibia, and fibula is filled.
- the light bone filling material can be filled efficiently and at a high filling rate.
- Each of the pellet-shaped bone replacement materials has a substantially polyhedral shape defined by a plurality of surfaces including a pair of opposed surfaces, and one surface of the pair of opposed surfaces is
- the plurality of pellet-like bone filling materials are inclined to the bone defect part using a device having a hollow lumen.
- the pellet-shaped bone filling material is introduced into the cavity and filled into the cavity, and the pellet-shaped bone filling material has an inclined surface adjacent to the hollow lumen.
- the bone filling material 1 introduced into the cavity of the bone defect spreads (disperses) in each direction, and It can be filled evenly. Further, the bone filling material introduced into the cavity does not stay near the opening of the instrument, and the cavity can be filled with a sufficient amount of the bone filling material.
- FIG. 1 is a perspective view showing a preferred embodiment of a bone replacement material of the present invention.
- FIG. 2 is a perspective view showing another example of the structure of the bone replacement material of the present invention.
- FIG. 3 is a perspective view showing another example of the structure of the bone substitute according to the present invention.
- FIG. 4 is a diagram for explaining a method for filling a vertebral body with a bone replacement material.
- FIG. 5 is a view for explaining a method for filling a vertebral body with a bone replacement material.
- FIG. 6 is a diagram for explaining a method of filling a bone filling material into a vertebral body.
- FIG. 7 is a view for explaining a method of filling a bone filling material into a vertebral body.
- FIG. 8 is a diagram for explaining a method for filling a vertebral body with a bone replacement material.
- FIG. 9 is a diagram for explaining a method of filling a bone filling material into a vertebral body.
- FIG. 10 is a diagram for explaining a method for filling a vertebral body with a bone replacement material.
- FIG. 11 is a diagram schematically showing vertebrae on which vertebral compression fracture reduction has been performed.
- FIG. 12 is a perspective view showing a configuration example of a guide rod.
- FIG. 13 is a perspective view showing a configuration example of a vertical elevator.
- FIG. 14 is a perspective view showing a configuration example of a horizontal elevator.
- FIG. 15 is a perspective view showing a configuration example of an inserter.
- FIG. 16 is a perspective view showing a configuration example of an impactor.
- FIG. 1 is a perspective view showing a preferred embodiment of the bone replacement material of the present invention.
- the bone replacement material of the present invention is used by filling a bone defect.
- the bone defect is a bone cavity caused by loss due to trauma, removal by removal operation of a tumor or the like, decrease in bone density due to osteoporosis or the like, or a combination thereof.
- the bone replacement material of the present invention comprises a bone defect of at least one kind of bone selected from the group consisting of vertebral body, iliac bone, scapula, humerus, ulna, radius, femur, tibia and fibula. It is suitably used for filling into stuffs. These bones have a relatively large size (dimension).
- the bone replacement material of the present invention can efficiently and at a high filling rate fill a bone defect of such a bone.
- the bone replacement material 1 (1A, 1B, 1C, ID) of the present invention is in the form of a pellet (small block), and is composed of a solid surrounded by a plurality of surfaces. Have been.
- a substantially spherical (granular) bone replacement material has been used in vertebral compression fracture reduction surgery.
- Such a conventional bone filling material has a small contact area between particles when filled in the vertebral body due to its shape.
- the conventional bone replacement material was not stable in the filled vertebral body, and tended to shift (move) due to the load.
- the density of the bone substitute material varies greatly at each site in the vertebral body. That is, there is a site in the vertebral body where the amount of bone replacement material is insufficient. As a result, the volume of the vertebral body was reduced by the load, and the effect of the operation could not be sufficiently obtained.
- the bone replacement material 1 of the present invention is formed of a solid surrounded by a plurality of surfaces, and has a substantially polyhedral shape. For this reason, the above-mentioned problem is unlikely to occur. That is, in the present invention However, since the individual bone replacement materials 1 come into contact with each other, they are fixed and stable. As a result, the vertebral body has a load resistance and can maintain a good filling state in the vertebral body for a long time without displacement even when used in a portion where the load is large.
- the bone replacement material 1 in a three-dimensional shape (substantially polyhedral shape) surrounded by a plurality of surfaces, the filling rate into the vertebral body is sufficiently increased (the number of voids is reduced). be able to. As a result, a decrease in the volume of the vertebral body can be suppressed after the operation, and the effect of the operation can be maintained for a long time.
- the bone prosthesis 1 since the bone prosthesis 1 has such a shape, it can effectively prevent the bone prosthesis 1 from remaining near the opening of the cylindrical body 51 described later when the bone prosthesis 1 is introduced into the cavity in the vertebral body.
- the vertebral body (cavity) can be easily filled with a sufficient amount of the bone replacement material 1.
- the clogging of the bone filling material 1 in the lumen of the cylindrical body 51 is also eliminated, so that the filling operation can be performed smoothly and reliably.
- the bone replacement material 1 of the present invention preferably satisfies one of the following conditions I and II, and more preferably satisfies both.
- the porosity of the bone replacement material 1 is preferably 75% or less, more preferably 50% or less, still more preferably 30% or less. By setting the porosity of the bone replacement material 1 within such a range, the load capacity of the bone replacement material 1 can be made sufficiently large. Therefore, the strong bone substitute 1 is suitable for application to a bone defect where a load is strong.
- the porosity of the bone replacement material 1 is relatively large (for example, 50% or more) in the above range, the osteoblast (osteocyte) inside the bone replacement material 1 can be reduced. It is easy to invade. Then, the bone replacement material 1 serves as a scaffold for osteoblasts, and their proliferation is promoted. As a result, bone formation is promoted and contributes to early bone formation. Therefore, the bone replacement material 1 has priority on bone union! And is suitable for application to a bone defect.
- the strength of the bone replacement material 1 may be reduced depending on the constituent materials and the like.
- the crushing strength of the bone replacement material 1 is preferably 15 MPa or more, more preferably 30 MPa or more, and even more preferably 150 MPa or more. Thereby, the withstand load of the bone replacement material 1 can be made sufficiently large.
- the crushing strength of the bone replacement material 1 is less than the lower limit value, for example, when the bone replacement material 1 is filled into a portion to which a strong and pressing force (external stress) is applied, such as a vertebral body, the bone replacement material 1 itself becomes It may be crushed early! / There is a possibility that the effect of the surgery may not be sufficiently obtained.
- the bone replacement material 1 may be of any shape as long as it has a three-dimensional shape (substantially polyhedral shape) surrounded by a plurality of surfaces, but it has a substantially columnar shape (partially removed). ), And those having a substantially hexahedral shape (including those with some parts removed) are more preferable, and those having a rectangular parallelepiped shape (with some parts removed) are more preferable. Is more preferable. With such a shape, the above-mentioned effects become more remarkable.
- the bone replacement material 1 of the present invention has at least one pair of opposing surfaces among a plurality of surfaces constituting the three-dimensional body (polyhedron).
- the surface is inclined by a predetermined angle ⁇ .
- the bone prosthesis 1 since the bone prosthesis 1 has such an inclined shape, the bone prosthesis 1 is efficiently dispersed at the time of filling the vertebral body (bone defect). Can be further increased.
- the bone substitute 1 having a shape in which the surface 11 is inclined by an angle ⁇ ⁇ ⁇ ⁇ with respect to the surface 12 facing the surface 11 by removing a part of the rectangular parallelepiped is shown as an example.
- the angle 0 is more preferably 20 to 40 degrees, preferably 20 to 40 degrees.
- the angle ⁇ is smaller than the lower limit, the effect of forming the inclined shape may not be sufficiently exerted.
- the angle ⁇ is larger than the upper limit, sharp projections are formed, and chips and the like are easily generated by the load.
- the bone replacement material 1 of the present invention preferably has a length L of the longest side of 1 to 10 mm, more preferably 5 to 7 mm.
- the length L of the longest side is shorter than the lower limit, the volume of each bone replacement material decreases, and the load bearing capacity decreases.
- the length L of the longest side is longer than the upper limit, dispersion inside the vertebral body is less likely to occur.
- the length of the shortest side L is preferably 2 to 5 mm.
- Bone augmentation material 1 One by one the body force is smaller, the load capacity is smaller. On the other hand, if the length of the shortest side is longer than the upper limit, it is difficult to fill the transpedicular force.
- the bone prosthetic material 1 of the present invention is more preferably the volume per the 13-239 mm 3 at and even preferred instrument 40- 100 mm 3. If the volume per piece is smaller than the lower limit, the volume of each bone replacement material will be small, and the load capacity will be small. On the other hand, if the volume per unit is larger than the upper limit, dispersion within the vertebral body (bone defect) becomes difficult to occur.
- the bone replacement material 1 of the present invention may have several types having different dimensions depending on the case (patient's body shape).
- the bone replacement material 1 of the present invention has been subjected to chamfering.
- the chamfering process prevents the bone replacement material 1 from inadvertently damaging living tissue during the filling operation into the vertebral body (bone defect) or while the vertebral body is being filled. You can do it.
- the bone replacement material 1 of the present invention is preferably composed of a material used as a biomaterial.
- a material used as a biomaterial for example, various ceramics such as anolemmina, zirconia, and phosphoric acid-based compounds can be mentioned. Among them, calcium phosphate-based compounds are preferable.
- a calcium phosphate compound can exist stably in a living body for a long period of time, and is particularly excellent as a biomaterial.
- Examples of the calcium phosphate compound include, for example, hydroxyapatite (Ca (PO) (
- a calcium phosphate compound having a CaZP specific force of 1.0 to 2.0 it is preferable to use a calcium phosphate compound having a CaZP specific force of 1.0 to 2.0.
- the CaZP ratio becomes close to the CaZP ratio of the living bone tissue, and it can be stably present in the living body for a longer period.
- FIG 2 and 3 are perspective views each showing another example of the structure of the bone replacement material of the present invention.
- the bone substitute 1 shown in FIGS. 2 and 3 is different from the bone substitute 1 shown in FIG.
- the description will focus on the points, and the description of the same items will be omitted.
- the bone filling material 1 shown in Fig. 2 has a substantially pentahedral shape, particularly a triangular prism shape, and a partially removed shape.
- the bone replacement material 1 shown in Fig. 1 has a triangular prism shape (including a shape in which a part of the bone filling material is removed).
- the bone filling material 1 shown in Fig. 3 has a substantially trihedral shape, particularly a cylindrical shape, and a partially removed shape.
- the same operation and effect as those of the bone replacement material 1 shown in Fig. 1 can also be obtained by the bone replacement material 1 shown in Fig. 3.
- the bone filling material 1 shown in FIG. 3 is formed of a continuous curved surface (not square), it is used for filling the vertebral body (bone defect) or filling the vertebral body. In the loaded state, it is possible to more reliably prevent the bone replacement material 1 from inadvertently damaging living tissue.
- the method for manufacturing such a bone replacement material 1 is not particularly limited.
- the bone replacement material 1 when the bone replacement material 1 is made of a ceramic material, the bone replacement material 1 can be manufactured as follows.
- a ceramic slurry is obtained by a known method.
- a water-soluble polymer is added to the ceramic slurry, and the mixture is stirred to generate air bubbles in the ceramic slurry.
- the ceramic slurry is supplied to a mold having a predetermined shape, and dried to obtain a molded body.
- the compacted body is sintered (fired). Thereby, a desired bone replacement material 1 is obtained.
- the conditions for synthesis of the raw material powder for example, the conditions for synthesis of the raw material powder (primary particle diameter, primary particle dispersion state, etc.) and the conditions for the raw material powder (average particle size, calcination)
- the conditions for foaming with stirring type of surfactant, stirring power for stirring the slurry, etc.
- the firing conditions firing atmosphere, firing temperature, etc.
- the porosity can be set as desired.
- FIGS. 12 to 16 are views showing an example of each surgical instrument used for vertebral compression fracture reduction including a filling operation of the bone replacement material 1.
- FIG. The surgical instruments used are not limited to these examples.
- FIG. 4 and FIGS. 8 and 10 show the vertebrae viewed obliquely from below (shown by cutting out a part of the vertebral body) on the upper side, and the vertebrae viewed from above on the lower side. Is shown.
- the left side is referred to as “distal end” and the right side is referred to as “proximal end”.
- the upper part of Figs. 4 and 8 and Fig. 10 and in Fig. 11 the upper part is "upper (head side)", the lower part is “lower part (leg side)”, and the left side is "front (belly)”.
- Side) J and the right side is “rear (back side) J.
- the guide rod 2 has a rod-shaped body 21 having a substantially circular cross section.
- the guide rod 2 has a rod-shaped body 21 having a different outer diameter (for example, ⁇ : 4 mm, 5 mm,
- the holes 93 can be gradually expanded by using these in order from the smaller diameter.
- the operation of expanding the diameter of the hole 93 is performed on the left and right holes 93.
- the vertical elevator 3 is used to reduce the upper part of the vertebral body 91, particularly the upper front part, to a substantially normal position.
- the vertical elevator 3 includes a rod-shaped main body 31, a pressing portion 32 provided at a distal end of the main body 31, and a grip portion 33 provided at a base end of the main body 31. Has ing.
- the pressing portion 32 and the distal end side of the main body 31 are inserted into the vertebral body 91 through one hole 93, and the pressing portion 32 is positioned at the front part. At this time, the distal end face 321 of the pressing portion 32 is kept in a state of facing upward.
- the pressing portion 32 can press the front upper portion of the vertebral body 91 upward while the distal end surface 321 of the pressing portion 32 abuts on the front upper inner surface of the vertebral body 91.
- the distal end side of the vertical elevator 3 is pulled out from the vertebra 9, inserted again into the vertebral body 91 through the other hole 93, and the same operation as described above is performed.
- the horizontal elevator 4 includes a rod-shaped main body 41, a pressing section 42 provided at a distal end of the main body 41, and a grip section provided at a base end of the main body 41. 43.
- the pressing portion 42 and the distal end side of the main body 41 are inserted into the vertebral body 91 through one hole 93, and the pressing portion 42 is positioned at the center. At this time, one side surface 421 of the pressing portion 42 is kept in an upward state.
- the pressing portion 42 can press the upper central portion of the vertebral body 91 and lift it upward while the side surface 421 of the pressing portion 42 abuts on the inner front surface of the vertebral body 91.
- the pressing section 42 is rotated by a predetermined angle about the axis of the main body 41, and the same operation as described above is performed.
- a reduction operation can be performed on a wider area in the upper center of the vertebral body 91.
- the distal end side of the horizontal elevator 4 is pulled out from the vertebra 9, inserted again into the vertebral body 91 through the other hole 93, and the same operation as described above is performed.
- a cavity 911 (bone defect) is formed therein.
- the inserter 5 includes, for example, a cylindrical body 51, an extruding rod 53 penetrating through the inner cavity of the cylindrical body 51, and a cylindrical body provided at the base end of the cylindrical body 51 as shown in FIG. It has a grip portion 52 and a push rod grip portion 54 provided at the base end of the push rod 53.
- the cylindrical body gripping portion 52 of the cylindrical body 51 is gripped with one hand, and the distal end side is inserted into the vertebral body 91 through one hole 93 as shown in FIG. Then, the tip of the cylindrical body 51 is positioned at a desired position of the cavity 911.
- the bone filling material 1 is loaded into the lumen of the cylindrical body 51 from the base end of the cylindrical body holding portion 52.
- the gripping portion 54 for the extrusion rod of the extrusion rod 53 is gripped by the other hand, and the extrusion rod 53 is inserted into the lumen of the cylindrical body 51 from the base end of the gripping portion 52 for the cylindrical body. Move in the direction.
- the bone replacement material 1 in the lumen of the cylindrical body 51 is pressed by the distal end of the push rod 53, and is transported in the cylindrical body 51 in the distal direction.
- the bone replacement material 1 of the present invention has the above-described shape, the operation of filling the vertebral body can be performed smoothly, reliably, and safely.
- the inclined shape as described above is formed, as shown in FIG. 9, when filling the bone replacement material 1 into the cavity 911 using the cylindrical body 51, the pushing rod 53 is used.
- the bone replacement material 1 is pushed in, the bone replacement material 1 is pushed out in a predetermined direction along the inclined shape portion of another adjacent bone replacement material 1.
- the pellet-shaped bone replacement material 1 has a substantially polyhedral shape defined by a plurality of surfaces including a pair of opposing surfaces, and the pair of opposing surfaces. Is inclined at a predetermined angle with respect to the other surface, and the bone replacement material 1 is When used in a damaged portion, the plurality of pellet-shaped bone replacement materials 1 are introduced into the cavity 911 of the bone defect portion using a cylindrical body (instrument) 51 having a hollow lumen, and are introduced into the cavity 911. It is to be filled.
- each of the pellet-shaped bone replacement materials 1 is inserted into the hollow lumen of the cylindrical body 51 so that its inclined surface faces the adjacent bone replacement material (preferably, the inclination of the adjacent bone replacement material). Face-to-face), so that their bone filling material is extruded in the hollow lumen force in various directions as shown in FIG.
- the bone replacement material 1A is pushed upward in the figure by the inclined shape portion of the bone replacement material 1B. Further, the bone replacement material 1B is extruded by the bone replacement material 1C in a direction substantially parallel to the cylinder 51. Further, the bone replacement material 1C is pushed downward in the figure by the bone replacement material 1D.
- the bone replacement material 1 has the above-described shape, even when a plurality of bone replacement materials 1 are continuously introduced into the vertebral body, for example, the bone replacement material 1 is introduced into the vertebral body.
- the bone filling material 1 diffuses (disperses) in each direction, so that the cavity 911 can be uniformly filled. Further, the bone replacement material 1 introduced into the cavity 911 does not stay near the opening of the cylindrical body 51, and the cavity replacement 911 can be filled with a sufficient amount of the bone replacement material 1.
- the bone filling material 1 is also effectively prevented from being clogged in the lumen of the cylindrical body 51, whereby the filling operation can be performed smoothly and reliably.
- the impactor 6 includes a rod-shaped main body 61, a pressing portion 62 provided at a distal end portion of the main body 61, and a base end portion of the main body 61. Holding portion 63.
- the gripper 63 of the impactor 6 is gripped and, as shown in FIG. And the distal end of the main body 61) are inserted into the vertebral body 91 through one hole 93.
- the bone filling material 1 filled in the cavity 911 in the operation [5] is pressed by the pressing portion 62. Thereby, the density (filling density) of the bone replacement material 1 can be increased.
- Such a filling operation [5] of the bone replacement material 1 and a densification operation [6] of the bone replacement material 1 are repeatedly performed a plurality of times through the left and right holes 93, respectively.
- the bone filling material 1 is filled in the cavity 911 of the vertebral body 91 and the density thereof is increased.
- This densification operation is performed more efficiently when the bone replacement material 1 has an inclined surface 11 (inclined surface). That is, when the bone filler 1 is pressed by the impactor 6, the plurality of bone fillers 1 are pushed into the unfilled portions of the cavity 911 so that they slide on each other on the inclined surface 11, and as a result, the cavity 911 Are densely packed.
- each of the left and right holes 93 is sealed with a plug 8 made of a biological material such as, for example, hydroxypropylapatite.
- a biological material such as, for example, hydroxypropylapatite.
- each hole 93 may be sealed with, for example, bone cement or the like instead of the plug 8.
- the operation is sutured, ligated, and the like, and the operation is completed.
- vertebral compression fracture reduction can be performed in a minimally invasive manner.
- the bone replacement material 1 of the present invention filled in the vertebral body has a three-dimensional shape (substantially polyhedral shape) surrounded by a plurality of surfaces as described above. They come into contact with each other and become fixed and stable. As a result, the vertebral body has good load resistance and can maintain a good filling state in the vertebral body without shifting even when used in a portion where the load is large.
- the filling operation of the bone replacement material can be performed smoothly, reliably, and safely.
- each part (portion) of the bone defect can be uniformly and sufficiently filled with the bone filling material.
Abstract
Description
Claims
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2004296674A AU2004296674B2 (en) | 2003-12-09 | 2004-12-09 | Bone supplementing material |
US10/596,303 US8034117B2 (en) | 2003-12-09 | 2004-12-09 | Bone replacement material |
EP04820250A EP1714622B1 (en) | 2003-12-09 | 2004-12-09 | Bone supplementing material |
DE602004020115T DE602004020115D1 (de) | 2003-12-09 | 2004-12-09 | Knochenergänzungsmaterial |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2003410873A JP4199653B2 (ja) | 2003-12-09 | 2003-12-09 | 骨補填材 |
JP2003-410873 | 2003-12-09 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2005055886A1 true WO2005055886A1 (ja) | 2005-06-23 |
Family
ID=34674958
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/JP2004/018359 WO2005055886A1 (ja) | 2003-12-09 | 2004-12-09 | 骨補填材 |
Country Status (8)
Country | Link |
---|---|
US (1) | US8034117B2 (ja) |
EP (1) | EP1714622B1 (ja) |
JP (1) | JP4199653B2 (ja) |
KR (1) | KR20060113940A (ja) |
CN (1) | CN100571654C (ja) |
AU (1) | AU2004296674B2 (ja) |
DE (1) | DE602004020115D1 (ja) |
WO (1) | WO2005055886A1 (ja) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2009018365A1 (en) | 2007-08-01 | 2009-02-05 | Jeffrey Halbrecht | Method and system for patella tendon realignment |
US20100198140A1 (en) * | 2009-02-05 | 2010-08-05 | Kevin Jon Lawson | Percutaneous tools and bone pellets for vertebral body reconstruction |
US9278004B2 (en) | 2009-08-27 | 2016-03-08 | Cotera, Inc. | Method and apparatus for altering biomechanics of the articular joints |
US9861408B2 (en) | 2009-08-27 | 2018-01-09 | The Foundry, Llc | Method and apparatus for treating canine cruciate ligament disease |
US9668868B2 (en) | 2009-08-27 | 2017-06-06 | Cotera, Inc. | Apparatus and methods for treatment of patellofemoral conditions |
CN116570353A (zh) | 2009-08-27 | 2023-08-11 | 铸造有限责任公司 | 用于改变膝关节中髌骨与股骨之间的负载及治疗髋关节疾病的设备 |
US10349980B2 (en) | 2009-08-27 | 2019-07-16 | The Foundry, Llc | Method and apparatus for altering biomechanics of the shoulder |
US9468466B1 (en) | 2012-08-24 | 2016-10-18 | Cotera, Inc. | Method and apparatus for altering biomechanics of the spine |
US20190134276A1 (en) * | 2016-06-23 | 2019-05-09 | Drexel University | Three dimensional porous cartilage template |
CN110236743A (zh) * | 2019-04-24 | 2019-09-17 | 宁波华科润生物科技有限公司 | 一种自凝固封口微创融合器 |
WO2021138081A1 (en) | 2020-01-02 | 2021-07-08 | Zkr Orthopedics, Inc. | Patella tendon realignment implant with changeable shape |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH021508B2 (ja) * | 1981-06-24 | 1990-01-11 | Kyocera Corp | |
JP2003135583A (ja) * | 2001-11-08 | 2003-05-13 | Pentax Corp | リン酸カルシウム−合成樹脂複合体及びその製造方法 |
JP2003210567A (ja) * | 2002-01-21 | 2003-07-29 | Toshiyuki Akazawa | 生体組織由来吸収性リン酸カルシウム傾斜機能複合材料とその作製方法 |
Family Cites Families (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0107476A3 (en) * | 1982-10-25 | 1985-01-02 | Calcitek, Inc. | Bone graft substitute |
JPS61170471A (ja) | 1985-01-25 | 1986-08-01 | 住友大阪セメント株式会社 | 骨補綴成形体 |
JP2827250B2 (ja) | 1988-02-16 | 1998-11-25 | キヤノン株式会社 | 位置検出装置 |
US5645596A (en) * | 1993-07-07 | 1997-07-08 | Asahi Kogaku Kogyo Kabushiki Kaisha | Ceramic vertebrae prosthesis |
JPH0810276A (ja) | 1994-06-28 | 1996-01-16 | Nippon Electric Glass Co Ltd | 脊椎補綴部材 |
US5639402A (en) * | 1994-08-08 | 1997-06-17 | Barlow; Joel W. | Method for fabricating artificial bone implant green parts |
CA2223596A1 (en) * | 1995-06-06 | 1996-12-12 | Osteogenics Inc. | Biocompatible hydroxyapatite formulations and uses therefor |
US5824078A (en) * | 1996-03-11 | 1998-10-20 | The Board Of Trustees Of The University Of Arkansas | Composite allograft, press, and methods |
US6187329B1 (en) * | 1997-12-23 | 2001-02-13 | Board Of Regents Of The University Of Texas System | Variable permeability bone implants, methods for their preparation and use |
US6139585A (en) * | 1998-03-11 | 2000-10-31 | Depuy Orthopaedics, Inc. | Bioactive ceramic coating and method |
AU766735B2 (en) * | 1998-09-15 | 2003-10-23 | Isotis N.V. | Osteoinduction |
US6725083B1 (en) * | 1999-02-02 | 2004-04-20 | Senorx, Inc. | Tissue site markers for in VIVO imaging |
WO2000062719A1 (en) * | 1999-04-16 | 2000-10-26 | Nuvasive, Inc. | Segmented linked intervertebral implant systems |
EP1178847B1 (fr) | 1999-05-19 | 2007-01-17 | Ecole Polytechnique Federale De Lausanne (Epfl) | Substitut osseux de type phosphate de calcium |
US6277149B1 (en) * | 1999-06-08 | 2001-08-21 | Osteotech, Inc. | Ramp-shaped intervertebral implant |
US6458162B1 (en) * | 1999-08-13 | 2002-10-01 | Vita Special Purpose Corporation | Composite shaped bodies and methods for their production and use |
US20040024465A1 (en) * | 1999-08-18 | 2004-02-05 | Gregory Lambrecht | Devices and method for augmenting a vertebral disc |
DE19940717A1 (de) * | 1999-08-26 | 2001-03-01 | Gerontocare Gmbh | Resorblerbares Knochenersatz- und Knochenaufbaumaterial |
JP4206453B2 (ja) | 1999-09-13 | 2009-01-14 | 建治 大畑 | 椎弓スペーサー |
US6264695B1 (en) * | 1999-09-30 | 2001-07-24 | Replication Medical, Inc. | Spinal nucleus implant |
JP3897220B2 (ja) | 2000-01-19 | 2007-03-22 | 独立行政法人物質・材料研究機構 | リン酸カルシウム系多孔質焼結体とその製造方法 |
JP2002113090A (ja) | 2000-10-12 | 2002-04-16 | Toshiba Ceramics Co Ltd | 生体用セラミックス多孔質部材 |
ES2237611T3 (es) * | 2000-10-24 | 2005-08-01 | Osteotech, Inc. | Composicion inyectable de aumento vertebral y metodo. |
DE10290985T5 (de) * | 2001-02-02 | 2004-04-15 | Technology Finance Corp. (Pty.) Ltd., Sandton | Knochenfüllmaterial |
JP4499327B2 (ja) | 2001-12-06 | 2010-07-07 | 松崎 浩巳 | 拡径器具および手術器具セット |
US6840961B2 (en) * | 2001-12-21 | 2005-01-11 | Etex Corporation | Machinable preformed calcium phosphate bone substitute material implants |
JP4179495B2 (ja) | 2002-06-12 | 2008-11-12 | 松崎 浩巳 | 骨補填材 |
US7252686B2 (en) * | 2003-08-13 | 2007-08-07 | Boston Scientific Scimed | Methods for reducing bone compression fractures using wedges |
-
2003
- 2003-12-09 JP JP2003410873A patent/JP4199653B2/ja not_active Expired - Lifetime
-
2004
- 2004-12-09 WO PCT/JP2004/018359 patent/WO2005055886A1/ja active Application Filing
- 2004-12-09 CN CNB2004800365486A patent/CN100571654C/zh not_active Expired - Fee Related
- 2004-12-09 KR KR1020067011170A patent/KR20060113940A/ko active IP Right Grant
- 2004-12-09 DE DE602004020115T patent/DE602004020115D1/de active Active
- 2004-12-09 AU AU2004296674A patent/AU2004296674B2/en not_active Ceased
- 2004-12-09 EP EP04820250A patent/EP1714622B1/en not_active Expired - Fee Related
- 2004-12-09 US US10/596,303 patent/US8034117B2/en not_active Expired - Fee Related
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH021508B2 (ja) * | 1981-06-24 | 1990-01-11 | Kyocera Corp | |
JP2003135583A (ja) * | 2001-11-08 | 2003-05-13 | Pentax Corp | リン酸カルシウム−合成樹脂複合体及びその製造方法 |
JP2003210567A (ja) * | 2002-01-21 | 2003-07-29 | Toshiyuki Akazawa | 生体組織由来吸収性リン酸カルシウム傾斜機能複合材料とその作製方法 |
Non-Patent Citations (1)
Title |
---|
See also references of EP1714622A4 * |
Also Published As
Publication number | Publication date |
---|---|
DE602004020115D1 (de) | 2009-04-30 |
JP2005168670A (ja) | 2005-06-30 |
AU2004296674A1 (en) | 2005-06-23 |
KR20060113940A (ko) | 2006-11-03 |
US8034117B2 (en) | 2011-10-11 |
US20070156247A1 (en) | 2007-07-05 |
EP1714622A1 (en) | 2006-10-25 |
JP4199653B2 (ja) | 2008-12-17 |
AU2004296674B2 (en) | 2011-03-31 |
CN1889901A (zh) | 2007-01-03 |
CN100571654C (zh) | 2009-12-23 |
EP1714622B1 (en) | 2009-03-18 |
EP1714622A4 (en) | 2007-10-24 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US10307511B2 (en) | Bioactive composites of polymer and glass and method for making same | |
US7374739B2 (en) | Calcium phosphate bone replacement materials and methods of use thereof | |
JP4179495B2 (ja) | 骨補填材 | |
US7087540B2 (en) | Resorbable bone replacement and bone formation material | |
US20050177237A1 (en) | Spinal cage insert, filler piece and method of manufacturing | |
KR20040081743A (ko) | 규격화된 예비성형 인산칼슘 뼈 대체물 임플란트 | |
WO2005055886A1 (ja) | 骨補填材 | |
EP2001527B1 (en) | Biomedical filler | |
Menon et al. | Radiological outcome of tibial plateau fractures treated with percutaneously introduced synthetic porous Hydroxyapatite granules. | |
JP2008237937A (ja) | 骨補填材 | |
Hsu | Fabrication of porous calcium phosphate bioceramics | |
US20130066427A1 (en) | Devices and Methods for Tissue Engineering | |
Lehmicke | Bioceramics-An Overview of Existing Materials and a Next Generation Composite of Calcium Phosphate Cement and Demineralized Bone | |
Cowden et al. | Effects of Compression During Formation on the Mechanical Strengths and Physical Properties of Composite Hydroxylapatite/Plaster Implants for Bone Reconstruction |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
WWE | Wipo information: entry into national phase |
Ref document number: 200480036548.6 Country of ref document: CN |
|
AK | Designated states |
Kind code of ref document: A1 Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BW BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE EG ES FI GB GD GE GH GM HR HU ID IL IN IS KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NA NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SY TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW |
|
AL | Designated countries for regional patents |
Kind code of ref document: A1 Designated state(s): BW GH GM KE LS MW MZ NA SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LT LU MC NL PL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG |
|
121 | Ep: the epo has been informed by wipo that ep was designated in this application | ||
WWE | Wipo information: entry into national phase |
Ref document number: 1020067011170 Country of ref document: KR |
|
WWE | Wipo information: entry into national phase |
Ref document number: 2004296674 Country of ref document: AU |
|
WWE | Wipo information: entry into national phase |
Ref document number: 2004820250 Country of ref document: EP |
|
ENP | Entry into the national phase |
Ref document number: 2004296674 Country of ref document: AU Date of ref document: 20041209 Kind code of ref document: A |
|
WWP | Wipo information: published in national office |
Ref document number: 2004296674 Country of ref document: AU |
|
WWP | Wipo information: published in national office |
Ref document number: 2004820250 Country of ref document: EP |
|
WWP | Wipo information: published in national office |
Ref document number: 1020067011170 Country of ref document: KR |
|
WWE | Wipo information: entry into national phase |
Ref document number: 10596303 Country of ref document: US |
|
WWP | Wipo information: published in national office |
Ref document number: 10596303 Country of ref document: US |