WO2005065284A3 - Tissue ablation with irreversible electroporation - Google Patents
Tissue ablation with irreversible electroporation Download PDFInfo
- Publication number
- WO2005065284A3 WO2005065284A3 PCT/US2004/043477 US2004043477W WO2005065284A3 WO 2005065284 A3 WO2005065284 A3 WO 2005065284A3 US 2004043477 W US2004043477 W US 2004043477W WO 2005065284 A3 WO2005065284 A3 WO 2005065284A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- irreversible electroporation
- cells
- tissue
- undesirable tissue
- ablation
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
- A61B18/1206—Generators therefor
- A61B18/1233—Generators therefor with circuits for assuring patient safety
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0408—Use-related aspects
- A61N1/0412—Specially adapted for transcutaneous electroporation, e.g. including drug reservoirs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
- A61B18/14—Probes or electrodes therefor
- A61B18/1477—Needle-like probes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00571—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for achieving a particular surgical effect
- A61B2018/00577—Ablation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00571—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for achieving a particular surgical effect
- A61B2018/00613—Irreversible electroporation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00636—Sensing and controlling the application of energy
- A61B2018/00696—Controlled or regulated parameters
- A61B2018/00714—Temperature
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00636—Sensing and controlling the application of energy
- A61B2018/00696—Controlled or regulated parameters
- A61B2018/00761—Duration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00636—Sensing and controlling the application of energy
- A61B2018/00773—Sensed parameters
- A61B2018/00827—Current
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
- A61B18/14—Probes or electrodes therefor
- A61B2018/1405—Electrodes having a specific shape
- A61B2018/1425—Needle
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0472—Structure-related aspects
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/327—Applying electric currents by contact electrodes alternating or intermittent currents for enhancing the absorption properties of tissue, e.g. by electroporation
Abstract
Priority Applications (14)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA2550846A CA2550846C (en) | 2003-12-24 | 2004-12-21 | Tissue ablation with irreversible electroporation |
AU2004311842A AU2004311842C1 (en) | 2003-12-24 | 2004-12-21 | Tissue ablation with irreversible electroporation |
PL04815540T PL1696812T3 (en) | 2003-12-24 | 2004-12-21 | Tissue ablation with irreversible electroporation |
EP04815540.2A EP1696812B1 (en) | 2003-12-24 | 2004-12-21 | Tissue ablation with irreversible electroporation |
EP12002108.4A EP2474281B1 (en) | 2003-12-24 | 2004-12-21 | Tissue ablation with irreversible electroporation |
DK04815540.2T DK1696812T3 (en) | 2003-12-24 | 2004-12-21 | Tissue ablation with irreversible electroporation |
US10/571,162 US8048067B2 (en) | 2003-12-24 | 2004-12-21 | Tissue ablation with irreversible electroporation |
ES04815540.2T ES2543832T3 (en) | 2003-12-24 | 2004-12-21 | Tissue ablation with irreversible electroporation |
JP2006547425A JP5138229B2 (en) | 2003-12-24 | 2004-12-21 | Tissue ablation by irreversible electroporation |
AU2010214761A AU2010214761B2 (en) | 2003-12-24 | 2010-09-01 | Tissue ablation with irreversible electroporation |
US13/237,199 US8282631B2 (en) | 2003-12-24 | 2011-09-20 | Tissue ablation with irreversible electroporation |
US13/546,339 US9005189B2 (en) | 2003-12-24 | 2012-07-11 | Tissue ablation with irreversible electroporation |
US14/639,632 US10117701B2 (en) | 2003-12-24 | 2015-03-05 | Tissue ablation with irreversible electroporation |
US16/160,205 US11033321B2 (en) | 2003-12-24 | 2018-10-15 | Tissue ablation with irreversible electroporation |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US53258803P | 2003-12-24 | 2003-12-24 | |
US60/532,588 | 2003-12-24 |
Related Child Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US10/571,162 A-371-Of-International US8048067B2 (en) | 2003-12-24 | 2004-12-21 | Tissue ablation with irreversible electroporation |
US13/237,199 Continuation US8282631B2 (en) | 2003-12-24 | 2011-09-20 | Tissue ablation with irreversible electroporation |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2005065284A2 WO2005065284A2 (en) | 2005-07-21 |
WO2005065284A3 true WO2005065284A3 (en) | 2005-11-17 |
Family
ID=34748811
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2004/043477 WO2005065284A2 (en) | 2003-12-24 | 2004-12-21 | Tissue ablation with irreversible electroporation |
Country Status (9)
Country | Link |
---|---|
US (8) | US8048067B2 (en) |
EP (2) | EP1696812B1 (en) |
JP (2) | JP5138229B2 (en) |
AU (2) | AU2004311842C1 (en) |
CA (1) | CA2550846C (en) |
DK (1) | DK1696812T3 (en) |
ES (2) | ES2543832T3 (en) |
PL (1) | PL1696812T3 (en) |
WO (1) | WO2005065284A2 (en) |
Cited By (16)
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US8845629B2 (en) | 2002-04-08 | 2014-09-30 | Medtronic Ardian Luxembourg S.A.R.L. | Ultrasound apparatuses for thermally-induced renal neuromodulation |
US8852163B2 (en) | 2002-04-08 | 2014-10-07 | Medtronic Ardian Luxembourg S.A.R.L. | Renal neuromodulation via drugs and neuromodulatory agents and associated systems and methods |
US8880186B2 (en) | 2002-04-08 | 2014-11-04 | Medtronic Ardian Luxembourg S.A.R.L. | Renal neuromodulation for treatment of patients with chronic heart failure |
US8948865B2 (en) | 2002-04-08 | 2015-02-03 | Medtronic Ardian Luxembourg S.A.R.L. | Methods for treating heart arrhythmia |
US9023037B2 (en) | 2002-04-08 | 2015-05-05 | Medtronic Ardian Luxembourg S.A.R.L. | Balloon catheter apparatus for renal neuromodulation |
US9108040B2 (en) | 2004-10-05 | 2015-08-18 | Medtronic Ardian Luxembourg S.A.R.L. | Methods and apparatus for multi-vessel renal neuromodulation |
US9131978B2 (en) | 2002-04-08 | 2015-09-15 | Medtronic Ardian Luxembourg S.A.R.L. | Methods for bilateral renal neuromodulation |
US9186213B2 (en) | 2002-04-08 | 2015-11-17 | Medtronic Ardian Luxembourg S.A.R.L. | Methods for renal neuromodulation |
US9192715B2 (en) | 2002-04-08 | 2015-11-24 | Medtronic Ardian Luxembourg S.A.R.L. | Methods for renal nerve blocking |
US9308039B2 (en) | 2006-09-14 | 2016-04-12 | Lazure Scientific, Inc. | Ablation probe with deployable electrodes |
US9308044B2 (en) | 2002-04-08 | 2016-04-12 | Medtronic Ardian Luxembourg S.A.R.L. | Methods for therapeutic renal neuromodulation |
US9308043B2 (en) | 2002-04-08 | 2016-04-12 | Medtronic Ardian Luxembourg S.A.R.L. | Methods for monopolar renal neuromodulation |
US9327122B2 (en) | 2002-04-08 | 2016-05-03 | Medtronic Ardian Luxembourg S.A.R.L. | Methods for catheter-based renal neuromodulation |
US9364280B2 (en) | 2002-04-08 | 2016-06-14 | Medtronic Ardian Luxembourg S.A.R.L. | Methods and apparatus for pulsed electric field neuromodulation via an intra-to-extravascular approach |
US9439726B2 (en) | 2002-04-08 | 2016-09-13 | Medtronic Ardian Luxembourg S.A.R.L. | Methods for therapeutic renal neuromodulation |
US9474563B2 (en) | 2002-04-08 | 2016-10-25 | Medtronic Ardian Luxembourg S.A.R.L. | Methods for renal neuromodulation |
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US6300108B1 (en) * | 1999-07-21 | 2001-10-09 | The Regents Of The University Of California | Controlled electroporation and mass transfer across cell membranes |
US6892099B2 (en) * | 2001-02-08 | 2005-05-10 | Minnesota Medical Physics, Llc | Apparatus and method for reducing subcutaneous fat deposits, virtual face lift and body sculpturing by electroporation |
US6795728B2 (en) | 2001-08-17 | 2004-09-21 | Minnesota Medical Physics, Llc | Apparatus and method for reducing subcutaneous fat deposits by electroporation |
US8251986B2 (en) | 2000-08-17 | 2012-08-28 | Angiodynamics, Inc. | Method of destroying tissue cells by eletroporation |
US6697670B2 (en) | 2001-08-17 | 2004-02-24 | Minnesota Medical Physics, Llc | Apparatus and method for reducing subcutaneous fat deposits by electroporation with improved comfort of patients |
US7130697B2 (en) * | 2002-08-13 | 2006-10-31 | Minnesota Medical Physics Llc | Apparatus and method for the treatment of benign prostatic hyperplasia |
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US8774913B2 (en) | 2002-04-08 | 2014-07-08 | Medtronic Ardian Luxembourg S.A.R.L. | Methods and apparatus for intravasculary-induced neuromodulation |
US8145317B2 (en) | 2002-04-08 | 2012-03-27 | Ardian, Inc. | Methods for renal neuromodulation |
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- 2004-12-21 PL PL04815540T patent/PL1696812T3/en unknown
- 2004-12-21 CA CA2550846A patent/CA2550846C/en active Active
- 2004-12-21 EP EP12002108.4A patent/EP2474281B1/en active Active
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Patent Citations (1)
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US6500173B2 (en) * | 1992-01-07 | 2002-12-31 | Ronald A. Underwood | Methods for electrosurgical spine surgery |
Non-Patent Citations (1)
Title |
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