WO2005072145A3 - Methods and systems for point of care bodily fluid analysis - Google Patents

Methods and systems for point of care bodily fluid analysis Download PDF

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Publication number
WO2005072145A3
WO2005072145A3 PCT/US2005/001260 US2005001260W WO2005072145A3 WO 2005072145 A3 WO2005072145 A3 WO 2005072145A3 US 2005001260 W US2005001260 W US 2005001260W WO 2005072145 A3 WO2005072145 A3 WO 2005072145A3
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WO
WIPO (PCT)
Prior art keywords
blood
systems
solution
care
methods
Prior art date
Application number
PCT/US2005/001260
Other languages
French (fr)
Other versions
WO2005072145A2 (en
Inventor
Zongcen Charles Xie
Jeffrey A Pierce
Carole R Stivers
Original Assignee
Metrika Inc
Zongcen Charles Xie
Jeffrey A Pierce
Carole R Stivers
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Metrika Inc, Zongcen Charles Xie, Jeffrey A Pierce, Carole R Stivers filed Critical Metrika Inc
Publication of WO2005072145A2 publication Critical patent/WO2005072145A2/en
Publication of WO2005072145A3 publication Critical patent/WO2005072145A3/en

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
    • G01N33/721—Haemoglobin
    • G01N33/723—Glycosylated haemoglobin

Abstract

The invention provides a system for quantitative measurement of percent glycated hemoglobin as hemoglobin A1c in whole blood having extended shelf life at room temperature. The system comprising a blood dilution solution and a device adapted for receiving at least a portion of diluted blood solution, for contacting the blood solution with a dry reagent system, for detecting a change in the reagent system and for providing an indication of the analytical result to the user, and the extended shelf life and the elimination of a requirement for refrigeration for storage is achieved by having the blood dilution solution which comprises a first surfactant for hemolysis and a second surfactant for stability. The system of this invention is useful in other analysis kits and systems as well.
PCT/US2005/001260 2004-01-16 2005-01-14 Methods and systems for point of care bodily fluid analysis WO2005072145A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/759,547 US7150995B2 (en) 2004-01-16 2004-01-16 Methods and systems for point of care bodily fluid analysis
US10/759,547 2004-01-16

Publications (2)

Publication Number Publication Date
WO2005072145A2 WO2005072145A2 (en) 2005-08-11
WO2005072145A3 true WO2005072145A3 (en) 2005-10-13

Family

ID=34749707

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/001260 WO2005072145A2 (en) 2004-01-16 2005-01-14 Methods and systems for point of care bodily fluid analysis

Country Status (2)

Country Link
US (1) US7150995B2 (en)
WO (1) WO2005072145A2 (en)

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