WO2005084534A8 - Personal diagnostic devices and related methods - Google Patents

Personal diagnostic devices and related methods

Info

Publication number
WO2005084534A8
WO2005084534A8 PCT/US2004/028964 US2004028964W WO2005084534A8 WO 2005084534 A8 WO2005084534 A8 WO 2005084534A8 US 2004028964 W US2004028964 W US 2004028964W WO 2005084534 A8 WO2005084534 A8 WO 2005084534A8
Authority
WO
WIPO (PCT)
Prior art keywords
chambers
diagnostic devices
bio
patches
bracelets
Prior art date
Application number
PCT/US2004/028964
Other languages
French (fr)
Other versions
WO2005084534A1 (en
Inventor
Brigitte Chau Phan
Andrew Atilla Pal
Ramoncito M Valencia
Donald Bollella
Original Assignee
Life Patch International Inc
Brigitte Chau Phan
Andrew Atilla Pal
Ramoncito M Valencia
Donald Bollella
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Life Patch International Inc, Brigitte Chau Phan, Andrew Atilla Pal, Ramoncito M Valencia, Donald Bollella filed Critical Life Patch International Inc
Priority to CN2004800320767A priority Critical patent/CN1874720B/en
Priority to JP2006526215A priority patent/JP2007503958A/en
Priority to BRPI0414067-2A priority patent/BRPI0414067A/en
Priority to AU2004317007A priority patent/AU2004317007A1/en
Priority to CA2537796A priority patent/CA2537796C/en
Priority to EP04821543A priority patent/EP1670356A1/en
Priority to KR1020067006489A priority patent/KR101165102B1/en
Publication of WO2005084534A1 publication Critical patent/WO2005084534A1/en
Publication of WO2005084534A8 publication Critical patent/WO2005084534A8/en
Priority to HK07105873.4A priority patent/HK1100761A1/en

Links

Classifications

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    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/12—Specific details about manufacturing devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/14—Process control and prevention of errors
    • B01L2200/143—Quality control, feedback systems
    • B—PERFORMING OPERATIONS; TRANSPORTING
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    • B01L2300/02—Identification, exchange or storage of information
    • B01L2300/023—Sending and receiving of information, e.g. using bluetooth
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/02—Identification, exchange or storage of information
    • B01L2300/025—Displaying results or values with integrated means
    • B01L2300/027—Digital display, e.g. LCD, LED
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0636—Integrated biosensor, microarrays
    • B—PERFORMING OPERATIONS; TRANSPORTING
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    • B—PERFORMING OPERATIONS; TRANSPORTING
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    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/069—Absorbents; Gels to retain a fluid
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
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    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/087—Multiple sequential chambers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
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    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0887—Laminated structure
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • B01L2400/049—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics vacuum
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0633—Valves, specific forms thereof with moving parts
    • B01L2400/0655—Valves, specific forms thereof with moving parts pinch valves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0677—Valves, specific forms thereof phase change valves; Meltable, freezing, dissolvable plugs; Destructible barriers

Abstract

Personal diagnostic devices including diagnostic patches (bio-patches) and interactive medical bracelets (bio-bracelets) are provided with a skin/patch interface, at least one analysis layer, a signal processing layer, and a user output interface. Embodiments of the interactive diagnostic devices may include micro-fluidic circuits with reaction chambers, analysis chambers, mixing chambers, and various pre-disposed chemistries or reagents for performing a wide verity of tests by trans-dermal transport of blood or perspiration. Sample collection chambers for the fluidic circuit may include minimally invasive tubules that penetrate the skin surface to acquire blood samples from capillaries near the epidermis. Alternate implementations of the personal diagnostic device may be equipped with logic processing, input/output devices, acoustic microphones, cryogenic circuits, embedded processors, electrical control circuitry, and battery current sources or photovoltaic sources of electrical power.
PCT/US2004/028964 2003-09-03 2004-09-02 Personal diagnostic devices and related methods WO2005084534A1 (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
CN2004800320767A CN1874720B (en) 2003-09-03 2004-09-02 Personal diagnostic devices
JP2006526215A JP2007503958A (en) 2003-09-03 2004-09-02 Personal diagnostic equipment and related methods
BRPI0414067-2A BRPI0414067A (en) 2003-09-03 2004-09-02 personal diagnostic device and method of using the same
AU2004317007A AU2004317007A1 (en) 2003-09-03 2004-09-02 Personal diagnostic devices and related methods
CA2537796A CA2537796C (en) 2003-09-03 2004-09-02 Personal diagnostic devices and related methods
EP04821543A EP1670356A1 (en) 2003-09-03 2004-09-02 Personal diagnostic devices and related methods
KR1020067006489A KR101165102B1 (en) 2003-09-03 2004-09-02 Personal diagnostic devices and related methods
HK07105873.4A HK1100761A1 (en) 2003-09-03 2007-06-04 Personal diagnostic devices

Applications Claiming Priority (4)

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US50010203P 2003-09-03 2003-09-03
US60/500,102 2003-09-03
US51076903P 2003-10-11 2003-10-11
US60/510,769 2003-10-11

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WO2005084534A8 true WO2005084534A8 (en) 2005-10-20

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US (5) US9133024B2 (en)
EP (1) EP1670356A1 (en)
JP (1) JP2007503958A (en)
KR (1) KR101165102B1 (en)
CN (2) CN102018496A (en)
AU (1) AU2004317007A1 (en)
BR (1) BRPI0414067A (en)
CA (1) CA2537796C (en)
HK (1) HK1100761A1 (en)
SG (1) SG146630A1 (en)
WO (1) WO2005084534A1 (en)

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8852101B2 (en) 2005-12-28 2014-10-07 Abbott Diabetes Care Inc. Method and apparatus for providing analyte sensor insertion
US8862198B2 (en) 2006-09-10 2014-10-14 Abbott Diabetes Care Inc. Method and system for providing an integrated analyte sensor insertion device and data processing unit
US9259175B2 (en) 2006-10-23 2016-02-16 Abbott Diabetes Care, Inc. Flexible patch for fluid delivery and monitoring body analytes
US9265453B2 (en) 2010-03-24 2016-02-23 Abbott Diabetes Care Inc. Medical device inserters and processes of inserting and using medical devices
US9351669B2 (en) 2009-09-30 2016-05-31 Abbott Diabetes Care Inc. Interconnect for on-body analyte monitoring device
US9398882B2 (en) 2005-09-30 2016-07-26 Abbott Diabetes Care Inc. Method and apparatus for providing analyte sensor and data processing device
US9402570B2 (en) 2011-12-11 2016-08-02 Abbott Diabetes Care Inc. Analyte sensor devices, connections, and methods
US9402544B2 (en) 2009-02-03 2016-08-02 Abbott Diabetes Care Inc. Analyte sensor and apparatus for insertion of the sensor
US9480421B2 (en) 2005-09-30 2016-11-01 Abbott Diabetes Care Inc. Integrated introducer and transmitter assembly and methods of use
US9521968B2 (en) 2005-09-30 2016-12-20 Abbott Diabetes Care Inc. Analyte sensor retention mechanism and methods of use
US9572534B2 (en) 2010-06-29 2017-02-21 Abbott Diabetes Care Inc. Devices, systems and methods for on-skin or on-body mounting of medical devices

Families Citing this family (295)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6036924A (en) 1997-12-04 2000-03-14 Hewlett-Packard Company Cassette of lancet cartridges for sampling blood
US6391005B1 (en) 1998-03-30 2002-05-21 Agilent Technologies, Inc. Apparatus and method for penetration with shaft having a sensor for sensing penetration depth
US8641644B2 (en) 2000-11-21 2014-02-04 Sanofi-Aventis Deutschland Gmbh Blood testing apparatus having a rotatable cartridge with multiple lancing elements and testing means
WO2002100461A2 (en) 2001-06-12 2002-12-19 Pelikan Technologies, Inc. Method and apparatus for improving success rate of blood yield from a fingerstick
US7025774B2 (en) 2001-06-12 2006-04-11 Pelikan Technologies, Inc. Tissue penetration device
US9226699B2 (en) 2002-04-19 2016-01-05 Sanofi-Aventis Deutschland Gmbh Body fluid sampling module with a continuous compression tissue interface surface
AU2002312521A1 (en) 2001-06-12 2002-12-23 Pelikan Technologies, Inc. Blood sampling apparatus and method
US7033371B2 (en) 2001-06-12 2006-04-25 Pelikan Technologies, Inc. Electric lancet actuator
US9427532B2 (en) 2001-06-12 2016-08-30 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
EP1404233B1 (en) 2001-06-12 2009-12-02 Pelikan Technologies Inc. Self optimizing lancing device with adaptation means to temporal variations in cutaneous properties
WO2002100254A2 (en) 2001-06-12 2002-12-19 Pelikan Technologies, Inc. Method and apparatus for lancet launching device integrated onto a blood-sampling cartridge
US9795747B2 (en) 2010-06-02 2017-10-24 Sanofi-Aventis Deutschland Gmbh Methods and apparatus for lancet actuation
US7981056B2 (en) 2002-04-19 2011-07-19 Pelikan Technologies, Inc. Methods and apparatus for lancet actuation
US7344507B2 (en) 2002-04-19 2008-03-18 Pelikan Technologies, Inc. Method and apparatus for lancet actuation
US8337419B2 (en) 2002-04-19 2012-12-25 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US7004928B2 (en) 2002-02-08 2006-02-28 Rosedale Medical, Inc. Autonomous, ambulatory analyte monitor or drug delivery device
US8858434B2 (en) 2004-07-13 2014-10-14 Dexcom, Inc. Transcutaneous analyte sensor
US6850788B2 (en) 2002-03-25 2005-02-01 Masimo Corporation Physiological measurement communications adapter
US7229458B2 (en) 2002-04-19 2007-06-12 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7909778B2 (en) 2002-04-19 2011-03-22 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7648468B2 (en) 2002-04-19 2010-01-19 Pelikon Technologies, Inc. Method and apparatus for penetrating tissue
US8221334B2 (en) 2002-04-19 2012-07-17 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7297122B2 (en) 2002-04-19 2007-11-20 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8784335B2 (en) 2002-04-19 2014-07-22 Sanofi-Aventis Deutschland Gmbh Body fluid sampling device with a capacitive sensor
US7371247B2 (en) 2002-04-19 2008-05-13 Pelikan Technologies, Inc Method and apparatus for penetrating tissue
US7547287B2 (en) 2002-04-19 2009-06-16 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7976476B2 (en) 2002-04-19 2011-07-12 Pelikan Technologies, Inc. Device and method for variable speed lancet
US8267870B2 (en) 2002-04-19 2012-09-18 Sanofi-Aventis Deutschland Gmbh Method and apparatus for body fluid sampling with hybrid actuation
US8579831B2 (en) 2002-04-19 2013-11-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7717863B2 (en) 2002-04-19 2010-05-18 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7901362B2 (en) 2002-04-19 2011-03-08 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8702624B2 (en) 2006-09-29 2014-04-22 Sanofi-Aventis Deutschland Gmbh Analyte measurement device with a single shot actuator
US7291117B2 (en) 2002-04-19 2007-11-06 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US9314194B2 (en) 2002-04-19 2016-04-19 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US7232451B2 (en) 2002-04-19 2007-06-19 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7713214B2 (en) 2002-04-19 2010-05-11 Pelikan Technologies, Inc. Method and apparatus for a multi-use body fluid sampling device with optical analyte sensing
US9795334B2 (en) 2002-04-19 2017-10-24 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7892183B2 (en) 2002-04-19 2011-02-22 Pelikan Technologies, Inc. Method and apparatus for body fluid sampling and analyte sensing
US9248267B2 (en) 2002-04-19 2016-02-02 Sanofi-Aventis Deustchland Gmbh Tissue penetration device
US7674232B2 (en) 2002-04-19 2010-03-09 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7491178B2 (en) 2002-04-19 2009-02-17 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7331931B2 (en) 2002-04-19 2008-02-19 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7381184B2 (en) 2002-11-05 2008-06-03 Abbott Diabetes Care Inc. Sensor inserter assembly
US8574895B2 (en) 2002-12-30 2013-11-05 Sanofi-Aventis Deutschland Gmbh Method and apparatus using optical techniques to measure analyte levels
US7052652B2 (en) 2003-03-24 2006-05-30 Rosedale Medical, Inc. Analyte concentration detection devices and methods
US7850621B2 (en) 2003-06-06 2010-12-14 Pelikan Technologies, Inc. Method and apparatus for body fluid sampling and analyte sensing
WO2006001797A1 (en) 2004-06-14 2006-01-05 Pelikan Technologies, Inc. Low pain penetrating
US7920906B2 (en) 2005-03-10 2011-04-05 Dexcom, Inc. System and methods for processing analyte sensor data for sensor calibration
JP2007503958A (en) * 2003-09-03 2007-03-01 ライフパッチ インターナショナル，インコーポレイテッド Personal diagnostic equipment and related methods
US8282576B2 (en) 2003-09-29 2012-10-09 Sanofi-Aventis Deutschland Gmbh Method and apparatus for an improved sample capture device
EP1680014A4 (en) 2003-10-14 2009-01-21 Pelikan Technologies Inc Method and apparatus for a variable user interface
USD902408S1 (en) 2003-11-05 2020-11-17 Abbott Diabetes Care Inc. Analyte sensor control unit
US9247900B2 (en) 2004-07-13 2016-02-02 Dexcom, Inc. Analyte sensor
US7822454B1 (en) 2005-01-03 2010-10-26 Pelikan Technologies, Inc. Fluid sampling device with improved analyte detecting member configuration
EP1706026B1 (en) 2003-12-31 2017-03-01 Sanofi-Aventis Deutschland GmbH Method and apparatus for improving fluidic flow and sample capture
ATE385572T1 (en) 2004-03-05 2008-02-15 Egomedical Swiss Ag ANALYTE TEST SYSTEM FOR DETERMINING THE CONCENTRATION OF AN ANALYTE IN A PHYSIOLOGICAL LIQUID
EP1751546A2 (en) 2004-05-20 2007-02-14 Albatros Technologies GmbH & Co. KG Printable hydrogel for biosensors
EP1765194A4 (en) 2004-06-03 2010-09-29 Pelikan Technologies Inc Method and apparatus for a fluid sampling device
EP1776464B1 (en) * 2004-08-13 2009-10-07 Egomedical Technologies AG Analyte test system for determining the concentration of an analyte in a physiological or aqueous fluid
US7883464B2 (en) 2005-09-30 2011-02-08 Abbott Diabetes Care Inc. Integrated transmitter unit and sensor introducer mechanism and methods of use
US8613703B2 (en) 2007-05-31 2013-12-24 Abbott Diabetes Care Inc. Insertion devices and methods
US9788771B2 (en) 2006-10-23 2017-10-17 Abbott Diabetes Care Inc. Variable speed sensor insertion devices and methods of use
US8571624B2 (en) 2004-12-29 2013-10-29 Abbott Diabetes Care Inc. Method and apparatus for mounting a data transmission device in a communication system
US7731657B2 (en) 2005-08-30 2010-06-08 Abbott Diabetes Care Inc. Analyte sensor introducer and methods of use
US9743862B2 (en) 2011-03-31 2017-08-29 Abbott Diabetes Care Inc. Systems and methods for transcutaneously implanting medical devices
US20090082693A1 (en) * 2004-12-29 2009-03-26 Therasense, Inc. Method and apparatus for providing temperature sensor module in a data communication system
US10226207B2 (en) 2004-12-29 2019-03-12 Abbott Diabetes Care Inc. Sensor inserter having introducer
US8029441B2 (en) 2006-02-28 2011-10-04 Abbott Diabetes Care Inc. Analyte sensor transmitter unit configuration for a data monitoring and management system
US20090105569A1 (en) 2006-04-28 2009-04-23 Abbott Diabetes Care, Inc. Introducer Assembly and Methods of Use
US8652831B2 (en) 2004-12-30 2014-02-18 Sanofi-Aventis Deutschland Gmbh Method and apparatus for analyte measurement test time
JP2008528170A (en) * 2005-01-31 2008-07-31 ギブン・イメージング・リミテツド In vivo analysis device, apparatus and method
US7671398B2 (en) * 2005-02-23 2010-03-02 Tran Bao Q Nano memory, light, energy, antenna and strand-based systems and methods
US8133178B2 (en) 2006-02-22 2012-03-13 Dexcom, Inc. Analyte sensor
US20090076360A1 (en) 2007-09-13 2009-03-19 Dexcom, Inc. Transcutaneous analyte sensor
US20060264783A1 (en) 2005-05-09 2006-11-23 Holmes Elizabeth A Systems and methods for monitoring pharmacological parameters
US20060281187A1 (en) 2005-06-13 2006-12-14 Rosedale Medical, Inc. Analyte detection devices and methods with hematocrit/volume correction and feedback control
JP2009506331A (en) * 2005-08-31 2009-02-12 エゴメディカル テクノロジーズ アクチエンゲゼルシャフト Analyte inspection system using non-enzymatic analyte recognition components
WO2007025559A1 (en) * 2005-08-31 2007-03-08 Egomedical Technologies Ag Coagulation test system
US8801631B2 (en) 2005-09-30 2014-08-12 Intuity Medical, Inc. Devices and methods for facilitating fluid transport
EP3461406A1 (en) 2005-09-30 2019-04-03 Intuity Medical, Inc. Multi-site body fluid sampling and analysis cartridge
US7499739B2 (en) 2005-10-27 2009-03-03 Smiths Medical Pm, Inc. Single use pulse oximeter
US7486977B2 (en) * 2005-10-27 2009-02-03 Smiths Medical Pm, Inc. Single use pulse oximeter
US20080179255A1 (en) * 2007-01-29 2008-07-31 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Fluidic devices
US20080178692A1 (en) * 2007-01-29 2008-07-31 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Fluidic methods
US20080241910A1 (en) * 2007-03-27 2008-10-02 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Devices for pathogen detection
US20080241000A1 (en) * 2007-03-27 2008-10-02 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Systems for pathogen detection
US20080241909A1 (en) * 2007-03-27 2008-10-02 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Microfluidic chips for pathogen detection
US20080193919A1 (en) * 2005-11-30 2008-08-14 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Systems and methods for receiving pathogen related information and responding
US11298058B2 (en) 2005-12-28 2022-04-12 Abbott Diabetes Care Inc. Method and apparatus for providing analyte sensor insertion
CA2636034A1 (en) 2005-12-28 2007-10-25 Abbott Diabetes Care Inc. Medical device insertion
CN101416048B (en) * 2006-01-12 2013-10-02 迈克罗拉布诊断有限公司 New instrumentation systems and methods
US9023278B2 (en) * 2006-01-12 2015-05-05 Micah James Atkin Instrumentation systems and methods
EP2013611A2 (en) * 2006-03-15 2009-01-14 The President and Fellows of Harvard College Nanobioelectronics
US8920343B2 (en) 2006-03-23 2014-12-30 Michael Edward Sabatino Apparatus for acquiring and processing of physiological auditory signals
US8741230B2 (en) 2006-03-24 2014-06-03 Theranos, Inc. Systems and methods of sample processing and fluid control in a fluidic system
US11287421B2 (en) 2006-03-24 2022-03-29 Labrador Diagnostics Llc Systems and methods of sample processing and fluid control in a fluidic system
US8007999B2 (en) 2006-05-10 2011-08-30 Theranos, Inc. Real-time detection of influenza virus
US20100216657A1 (en) * 2006-05-16 2010-08-26 Arcxis Biotechnologies, Inc. Pcr-free sample preparation and detection systems for high speed biologic analysis and identification
EP2035584B1 (en) 2006-06-12 2011-01-26 President and Fellows of Harvard College Nanosensors and related technologies
WO2008006154A1 (en) * 2006-07-11 2008-01-17 Paul Nigel Brockwell Health indicator method and device
US20090047673A1 (en) 2006-08-22 2009-02-19 Cary Robert B Miniaturized lateral flow device for rapid and sensitive detection of proteins or nucleic acids
US20080176755A1 (en) * 2006-08-25 2008-07-24 The Trustees Of Columbia University In The City Of New York, Office Of The General Counsel Systems and methods for biodosimetry with biochip using gene expression signatures
EP2089410A4 (en) * 2006-10-11 2011-08-03 Arcxis Biotechnologies Inc Disposable micropurification cards, methods, and systems thereof
US8012744B2 (en) 2006-10-13 2011-09-06 Theranos, Inc. Reducing optical interference in a fluidic device
US8579853B2 (en) * 2006-10-31 2013-11-12 Abbott Diabetes Care Inc. Infusion devices and methods
US20080113391A1 (en) * 2006-11-14 2008-05-15 Ian Gibbons Detection and quantification of analytes in bodily fluids
US8575663B2 (en) 2006-11-22 2013-11-05 President And Fellows Of Harvard College High-sensitivity nanoscale wire sensors
WO2008071218A1 (en) * 2006-12-14 2008-06-19 Egomedical Swiss Ag Monitoring device
US20080180259A1 (en) * 2007-01-29 2008-07-31 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Devices for allergen detection
US20080181816A1 (en) * 2007-01-29 2008-07-31 Searete Llc, A Limited Liability Corporation Systems for allergen detection
US20080181821A1 (en) * 2007-01-29 2008-07-31 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Microfluidic chips for allergen detection
WO2008092470A1 (en) * 2007-01-29 2008-08-07 Egomedical Swiss Ag Resealeable container for storing moisture sensitive test elements
US10001496B2 (en) * 2007-01-29 2018-06-19 Gearbox, Llc Systems for allergen detection
US8617903B2 (en) * 2007-01-29 2013-12-31 The Invention Science Fund I, Llc Methods for allergen detection
US20080245740A1 (en) * 2007-01-29 2008-10-09 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Fluidic methods
US20090050569A1 (en) * 2007-01-29 2009-02-26 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Fluidic methods
US7821637B1 (en) 2007-02-22 2010-10-26 J.A. Woollam Co., Inc. System for controlling intensity of a beam of electromagnetic radiation and method for investigating materials with low specular reflectance and/or are depolarizing
US20090227005A1 (en) * 2007-03-27 2009-09-10 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Methods for pathogen detection
US20080275326A1 (en) * 2007-05-01 2008-11-06 Joachim Kasielke Sensor for monitoring a condition of a patient
US8158430B1 (en) 2007-08-06 2012-04-17 Theranos, Inc. Systems and methods of fluidic sample processing
US8088593B2 (en) 2007-10-02 2012-01-03 Theranos, Inc. Modular point-of-care devices, systems, and uses thereof
EP2056114A1 (en) * 2007-10-29 2009-05-06 Koninklijke Philips Electronics N.V. Automatic detection of infectious diseases
JP4952525B2 (en) * 2007-11-09 2012-06-13 オムロンヘルスケア株式会社 Blood component concentration measuring apparatus and blood component concentration measuring method
JP5186887B2 (en) * 2007-11-09 2013-04-24 オムロンヘルスケア株式会社 Blood component concentration measuring apparatus and blood component concentration measuring method
JP5374861B2 (en) 2007-11-09 2013-12-25 オムロンヘルスケア株式会社 Blood component concentration measuring device and method for controlling blood component concentration measuring device
KR20090092506A (en) * 2008-02-27 2009-09-01 케이엠에이치 주식회사 Glucose measuring system
WO2009126900A1 (en) 2008-04-11 2009-10-15 Pelikan Technologies, Inc. Method and apparatus for analyte detecting device
WO2009137059A1 (en) 2008-05-05 2009-11-12 Los Alamos National Security, Llc Highly simplified lateral flow-based nucleic acid sample preparation and passive fluid flow control
US9833183B2 (en) 2008-05-30 2017-12-05 Intuity Medical, Inc. Body fluid sampling device—sampling site interface
EP3984454A1 (en) 2008-06-06 2022-04-20 Intuity Medical, Inc. Medical diagnostic devices and methods
CA2726067C (en) * 2008-06-06 2020-10-20 Intuity Medical, Inc. Detection meter and mode of operation
WO2010023577A1 (en) * 2008-08-28 2010-03-04 Koninklijke Philips Electronics, N.V. Method and system for providing a patient identification beacon for patient worn sensors
US20100130843A1 (en) * 2008-11-24 2010-05-27 Tecnicas Cientificas Para Laboratorio, S.A Wireless device for confirmatory diagnosis of cystic fibrosis through analysis of sweat chloride
US20100137575A1 (en) * 2008-12-03 2010-06-03 Connolly D Michael Universal biological sample processing
US9375169B2 (en) 2009-01-30 2016-06-28 Sanofi-Aventis Deutschland Gmbh Cam drive for managing disposable penetrating member actions with a single motor and motor and control system
US20100198188A1 (en) * 2009-02-05 2010-08-05 Abbott Diabetes Care Inc. Devices and Methods for Metering Insoluble Active Agent Particles
US10136816B2 (en) 2009-08-31 2018-11-27 Abbott Diabetes Care Inc. Medical devices and methods
JP6078230B2 (en) 2009-03-02 2017-02-08 セブンス センス バイオシステムズ，インコーポレーテッド Techniques and devices related to blood sampling
US9295417B2 (en) 2011-04-29 2016-03-29 Seventh Sense Biosystems, Inc. Systems and methods for collecting fluid from a subject
US20110046466A1 (en) * 2009-08-19 2011-02-24 Feldman Benjamin J Analyte Sensors Including Nanomaterials and Methods of Using Same
DE102009029215A1 (en) * 2009-09-04 2011-03-10 Robert Bosch Gmbh Device for determining body functions
US9297796B2 (en) 2009-09-24 2016-03-29 President And Fellows Of Harvard College Bent nanowires and related probing of species
EP2491499A4 (en) 2009-10-19 2016-05-18 Theranos Inc Integrated health data capture and analysis system
EP2493537B1 (en) * 2009-10-30 2017-12-06 Seventh Sense Biosystems, Inc. Systems and methods for treating, sanitizing, and/or shielding the skin or devices applied to the skin
WO2011053788A2 (en) * 2009-10-30 2011-05-05 Seventh Sense Biosystems, Inc. Relatively small devices applied to the skin, modular systems, and methods of use thereof
EP2506768B1 (en) 2009-11-30 2016-07-06 Intuity Medical, Inc. Calibration material delivery devices and methods
JP5808342B2 (en) * 2010-01-28 2015-11-10 エリューム・ピーティーワイ・リミテッド Sampling and testing devices for the human or animal body
WO2011094573A1 (en) 2010-01-28 2011-08-04 Seventh Sense Biosystems, Inc. Monitoring or feedback systems and methods
USD924406S1 (en) 2010-02-01 2021-07-06 Abbott Diabetes Care Inc. Analyte sensor inserter
US8965476B2 (en) 2010-04-16 2015-02-24 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
WO2011163347A2 (en) 2010-06-23 2011-12-29 Seventh Sense Biosystems, Inc. Sampling devices and methods involving relatively little pain
CA2803797A1 (en) 2010-06-25 2011-12-29 Intuity Medical, Inc. Analyte monitoring methods and systems
US11064921B2 (en) 2010-06-29 2021-07-20 Abbott Diabetes Care Inc. Devices, systems and methods for on-skin or on-body mounting of medical devices
CN103109186B (en) * 2010-06-30 2016-06-22 安派科生物医学科技有限公司 Disease detection instrument
US20120016308A1 (en) 2010-07-16 2012-01-19 Seventh Sense Biosystems, Inc. Low-pressure packaging for fluid devices
CN103140755B (en) 2010-07-22 2016-03-16 哈希公司 For the lab on A Chip of alkalinity analyzing
US20130158482A1 (en) 2010-07-26 2013-06-20 Seventh Sense Biosystems, Inc. Rapid delivery and/or receiving of fluids
WO2012021801A2 (en) 2010-08-13 2012-02-16 Seventh Sense Biosystems, Inc. Systems and techniques for monitoring subjects
JP6055773B2 (en) 2010-11-09 2016-12-27 セブンス センス バイオシステムズ，インコーポレーテッド System and interface for blood sampling
CN111982829A (en) 2011-01-21 2020-11-24 拉布拉多诊断有限责任公司 System and method for maximizing sample usage
US20120197622A1 (en) * 2011-01-31 2012-08-02 Fujitsu Limited Monitoring Insulin Resistance
US20120197621A1 (en) * 2011-01-31 2012-08-02 Fujitsu Limited Diagnosing Insulin Resistance
US9488613B2 (en) * 2011-03-02 2016-11-08 Massachusetts Institute Of Technology Systems, devices and methods for multiplexed diagnostics
DK2688474T3 (en) 2011-03-25 2015-05-11 Sanofi Aventis Deutschland Device and method for analysis of body fluid
US8911941B2 (en) * 2011-04-14 2014-12-16 Kenneth J. Michlitsch Methods and apparatus for point-of-care nucleic acid amplification and detection
US9469871B2 (en) 2011-04-14 2016-10-18 Corporos Inc. Methods and apparatus for point-of-care nucleic acid amplification and detection
KR101508670B1 (en) 2011-04-20 2015-04-07 메사 테크 인터내셔널, 인코포레이티드 Integrated device for nucleic acid detection and identification
US20130158468A1 (en) 2011-12-19 2013-06-20 Seventh Sense Biosystems, Inc. Delivering and/or receiving material with respect to a subject surface
EP2701600B1 (en) 2011-04-29 2016-06-08 Seventh Sense Biosystems, Inc. Delivering and/or receiving fluids
CA2833175A1 (en) 2011-04-29 2012-11-01 Seventh Sense Biosystems, Inc. Devices and methods for collection and/or manipulation of blood spots or other bodily fluids
GB2491813A (en) * 2011-06-03 2012-12-19 Univ Dublin City A microfluidic device with sacrificial valve
WO2012170630A2 (en) 2011-06-10 2012-12-13 President And Fellows Of Harvard College Nanoscale wires, nanoscale wire fet devices, and nanotube-electronic hybrid devices for sensing and other applications
EP3750480B1 (en) 2011-08-03 2022-02-02 Intuity Medical, Inc. Body fluid sampling arrangement
US9632102B2 (en) 2011-09-25 2017-04-25 Theranos, Inc. Systems and methods for multi-purpose analysis
US20140170735A1 (en) 2011-09-25 2014-06-19 Elizabeth A. Holmes Systems and methods for multi-analysis
US9268915B2 (en) 2011-09-25 2016-02-23 Theranos, Inc. Systems and methods for diagnosis or treatment
US8840838B2 (en) 2011-09-25 2014-09-23 Theranos, Inc. Centrifuge configurations
US9664702B2 (en) 2011-09-25 2017-05-30 Theranos, Inc. Fluid handling apparatus and configurations
US8475739B2 (en) 2011-09-25 2013-07-02 Theranos, Inc. Systems and methods for fluid handling
US9619627B2 (en) 2011-09-25 2017-04-11 Theranos, Inc. Systems and methods for collecting and transmitting assay results
US9250229B2 (en) 2011-09-25 2016-02-02 Theranos, Inc. Systems and methods for multi-analysis
US9810704B2 (en) 2013-02-18 2017-11-07 Theranos, Inc. Systems and methods for multi-analysis
US10012664B2 (en) 2011-09-25 2018-07-03 Theranos Ip Company, Llc Systems and methods for fluid and component handling
WO2013067272A1 (en) * 2011-11-04 2013-05-10 Diagnostics For All, Inc. Low cost, disposable molecular diagnostic devices
JP5884831B2 (en) * 2011-12-27 2016-03-15 ソニー株式会社 Information processing apparatus and method
WO2013152087A2 (en) 2012-04-04 2013-10-10 University Of Cincinnati Sweat simulation, collection and sensing systems
WO2013159117A1 (en) * 2012-04-20 2013-10-24 SlipChip, LLC Fluidic devices and systems for sample preparation or autonomous analysis
US9354159B2 (en) 2012-05-02 2016-05-31 Nanoscopia (Cayman), Inc. Opto-fluidic system with coated fluid channels
US9180449B2 (en) 2012-06-12 2015-11-10 Hach Company Mobile water analysis
US9523865B2 (en) 2012-07-26 2016-12-20 Verily Life Sciences Llc Contact lenses with hybrid power sources
US10890590B2 (en) 2012-09-27 2021-01-12 Ellume Limited Diagnostic devices and methods
USD768872S1 (en) 2012-12-12 2016-10-11 Hach Company Cuvette for a water analysis instrument
US9759672B2 (en) * 2012-12-19 2017-09-12 James Francis Ziegler Radiation detecting wearable devices
US11389114B2 (en) * 2013-01-02 2022-07-19 FIBROTX OÜ{umlaut over ( )} Device to measure analytes in the skin
EP2762066A1 (en) 2013-02-05 2014-08-06 Koninklijke Philips N.V. System and method for determining vital sign information of a subject
US20140323819A1 (en) * 2013-04-29 2014-10-30 Elwha LLC, a limited liability company of the State of Delaware Multi-parameter test units for initial indication of medical symptoms
CA2912283A1 (en) 2013-06-21 2014-12-21 Intuity Medical, Inc. Analyte monitoring system with audible feedback
WO2015009970A1 (en) 2013-07-18 2015-01-22 Erythron Llc Spectroscopic measurements with parallel array detector
US10422806B1 (en) 2013-07-25 2019-09-24 Theranos Ip Company, Llc Methods for improving assays of biological samples
CN103445763B (en) * 2013-08-26 2015-08-26 华中科技大学 A kind of health monitoring systems based on epidermis electronics
US20150064672A1 (en) * 2013-09-05 2015-03-05 Matthew Bars Systems and methods for treatment of substance addiction
US8742623B1 (en) 2013-09-16 2014-06-03 Google Inc. Device with dual power sources
EP3052234A2 (en) * 2013-09-30 2016-08-10 Göran Stemme A microfluidic device, use and methods
US10136831B2 (en) 2013-10-18 2018-11-27 University Of Cincinnati Sweat sensing with chronological assurance
EP3165154A3 (en) 2013-10-18 2017-07-26 University of Cincinnati Devices for integrated, repeated, prolonged, and/or reliable sweat stimulation and biosensing
US10888244B2 (en) 2013-10-18 2021-01-12 University Of Cincinnati Sweat sensing with chronological assurance
US20150173674A1 (en) * 2013-12-20 2015-06-25 Diabetes Sentry Products Inc. Detecting and communicating health conditions
US20150338338A1 (en) 2014-02-28 2015-11-26 Erythron, Llc Method and Apparatus for Determining Markers of Health by Analysis of Blood
GB2548944B (en) 2014-04-17 2018-11-28 Z Integrated Digital Tech Inc Electronic test device data communication
US10413565B2 (en) 2014-04-30 2019-09-17 Northwestern University Nanostructures for modulating intercellular communication and uses thereof
JP2017518814A (en) 2014-05-28 2017-07-13 ユニバーシティ・オブ・シンシナティ Sweat monitoring and drug delivery control
WO2015184072A1 (en) 2014-05-28 2015-12-03 University Of Cincinnati Advanced sweat sensor adhesion, sealing, and fluidic strategies
US10639015B2 (en) 2014-05-28 2020-05-05 University Of Cincinnati Devices with reduced sweat volumes between sensors and sweat glands
US10736551B2 (en) * 2014-08-11 2020-08-11 The Board Of Trustees Of The University Of Illinois Epidermal photonic systems and methods
JP2017529216A (en) 2014-09-22 2017-10-05 ユニバーシティ・オブ・シンシナティ Sweat perception with analytical assurance
CN107249451A (en) 2014-10-15 2017-10-13 外分泌腺系统公司 Sweat sensing device communications security and compliance
CN104434063A (en) * 2014-11-24 2015-03-25 深圳市华宝电子科技有限公司 Remote real-time monitoring system
KR20160089718A (en) 2015-01-20 2016-07-28 삼성전자주식회사 Sensor module and wearable analyzing device for body compositon with the same
EP3248001B1 (en) 2015-01-22 2019-09-18 Ellume Pty Ltd. Diagnostic devices and methods for mitigating hook effect and use thereof
CN111067544B (en) 2015-02-13 2023-04-07 辛辛那提大学 Device integrating indirect sweat stimulation and sensing
CN107530004A (en) 2015-02-20 2018-01-02 Mc10股份有限公司 The automatic detection and construction of wearable device based on personal situation, position and/or orientation
US11883011B2 (en) * 2015-03-09 2024-01-30 CoreSyte, Inc. Method for manufacturing a biological fluid sensor
US10561405B2 (en) * 2015-03-09 2020-02-18 CoreSyte, Inc. Method for manufacturing a biological fluid sensor
US11389087B2 (en) 2015-03-09 2022-07-19 CoreSyte, Inc. Device for measuring biological fluids
WO2016168090A1 (en) 2015-04-14 2016-10-20 Nueon, Inc. Method and apparatus for determining markers of health by analysis of blood
EP3294133B1 (en) * 2015-05-14 2019-09-04 General Electric Company Method and kit for separation and collection of plasma
WO2016183493A1 (en) 2015-05-14 2016-11-17 Abbott Diabetes Care Inc. Compact medical device inserters and related systems and methods
US20160367194A1 (en) * 2015-05-14 2016-12-22 Richard Murphy Illumination system for mobile devices
US10213139B2 (en) 2015-05-14 2019-02-26 Abbott Diabetes Care Inc. Systems, devices, and methods for assembling an applicator and sensor control device
US11260386B2 (en) * 2015-06-05 2022-03-01 The Emerther Company Component of a device, a device, and a method for purifying and testing biomolecules from biological samples
US10646142B2 (en) 2015-06-29 2020-05-12 Eccrine Systems, Inc. Smart sweat stimulation and sensing devices
US10105100B2 (en) * 2015-07-28 2018-10-23 Verily Life Sciences Llc Display on a bandage-type monitoring device
US20170103669A1 (en) * 2015-10-09 2017-04-13 Fuji Xerox Co., Ltd. Computer readable recording medium and system for providing automatic recommendations based on physiological data of individuals
EP3364862A4 (en) 2015-10-23 2019-10-23 Eccrine Systems, Inc. Devices capable of sample concentration for extended sensing of sweat analytes
US10674946B2 (en) 2015-12-18 2020-06-09 Eccrine Systems, Inc. Sweat sensing devices with sensor abrasion protection
KR102145769B1 (en) * 2016-01-25 2020-08-19 교세라 가부시키가이샤 Measurement sensor package and measurement sensor
US10277386B2 (en) 2016-02-22 2019-04-30 Mc10, Inc. System, devices, and method for on-body data and power transmission
US11039986B2 (en) 2016-02-25 2021-06-22 Samsung Electronics Co., Ltd. Chronotherapeutic dosing of medication and medication regimen adherence
WO2017165403A1 (en) 2016-03-21 2017-09-28 Nueon Inc. Porous mesh spectrometry methods and apparatus
TW201800069A (en) 2016-03-30 2018-01-01 康華特科技有限公司 Detecting microbial infection in wounds
CN109310340A (en) * 2016-04-19 2019-02-05 Mc10股份有限公司 For measuring the method and system of sweat
US11172879B2 (en) 2016-05-09 2021-11-16 King Abdullah University Of Science And Technology Wearable personalized medicinal platform
US10471249B2 (en) 2016-06-08 2019-11-12 University Of Cincinnati Enhanced analyte access through epithelial tissue
EP3478186A4 (en) 2016-07-01 2020-03-04 University of Cincinnati Devices with reduced microfluidic volume between sensors and sweat glands
WO2018013579A1 (en) * 2016-07-11 2018-01-18 cARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY Sweat as a biofluid for analysis and disease identification
WO2018017619A1 (en) 2016-07-19 2018-01-25 Eccrine Systems, Inc. Sweat conductivity, volumetric sweat rate and galvanic skin response devices and applications
EP3272285B1 (en) * 2016-07-20 2019-06-05 Techkon GmbH Device and method for measuring variables or parameters of a bodily fluid
JP6689699B2 (en) * 2016-07-22 2020-04-28 シスメックス株式会社 Blood collection tool and blood collection set
US10447347B2 (en) 2016-08-12 2019-10-15 Mc10, Inc. Wireless charger and high speed data off-loader
US11389096B2 (en) * 2016-09-10 2022-07-19 Ecole Polytechnique Federale De Lausanne (Epfl) Bio-fluid collection and sensing device, system and method
EP3513200A4 (en) * 2016-09-15 2020-07-29 Northwestern University Nanoparticles as catalytic substrates for real-time biosensing of human performance and diagnostic and therapeutic methods
US10736565B2 (en) 2016-10-14 2020-08-11 Eccrine Systems, Inc. Sweat electrolyte loss monitoring devices
WO2018085699A1 (en) 2016-11-04 2018-05-11 Nueon Inc. Combination blood lancet and analyzer
DE112016007510T5 (en) * 2016-12-08 2019-09-26 Intel Corporation BODY-PORTABLE ASSAY SYSTEM AND USE METHOD
WO2018136898A1 (en) 2017-01-23 2018-07-26 Abbott Diabetes Care Inc. Systems, devices and methods for analyte sensor insertion
EP3357422A1 (en) * 2017-02-07 2018-08-08 Koninklijke Philips N.V. Microneedles and insertable devices with integrated antenna array
US20180256111A1 (en) * 2017-03-07 2018-09-13 Primus Llc Apparatus and method to record health care vitals and information on a stand-alone and mobile device.
US11406321B2 (en) 2017-07-25 2022-08-09 Epicore Biosystems, Inc. Wearable fluidic system for measuring sweat composition
US11709468B2 (en) * 2017-07-25 2023-07-25 Life Patch International User comfort control system having non-invasive bio-patch
JP7391020B2 (en) 2017-08-17 2023-12-04 ロジックインク コーポレーション Wearable colorimetric sensing of markers for airborne particulate matter pollution
TWI644101B (en) * 2017-08-29 2018-12-11 瑞瑩生醫科技股份有限公司 A test strip for electrochemical biosensor with high stability and manufacturing method thereof
US10123702B1 (en) 2017-08-31 2018-11-13 Jennifer Wilkins Patient monitoring system
EP3684463A4 (en) 2017-09-19 2021-06-23 Neuroenhancement Lab, LLC Method and apparatus for neuroenhancement
FR3072270B1 (en) * 2017-10-13 2020-01-31 Devinnova SKIN SURVEILLANCE SYSTEM FOR AN INDIVIDUAL
US11331009B2 (en) 2017-10-16 2022-05-17 Xsensio SA Apparatus for non-invasive sensing of biomarkers in human sweat
KR102399533B1 (en) * 2017-10-18 2022-05-19 삼성전자주식회사 Electronic device and method for providing stress index corresponding to activity of user
US11717686B2 (en) 2017-12-04 2023-08-08 Neuroenhancement Lab, LLC Method and apparatus for neuroenhancement to facilitate learning and performance
US11318277B2 (en) 2017-12-31 2022-05-03 Neuroenhancement Lab, LLC Method and apparatus for neuroenhancement to enhance emotional response
US11060968B2 (en) * 2018-03-30 2021-07-13 International Business Machines Corporation Mobile chemical analysis
US11585882B2 (en) * 2018-04-11 2023-02-21 Mars Sciences Limited Superparamagnetic particle imaging and its applications in quantitative multiplex stationary phase diagnostic assays
US11364361B2 (en) 2018-04-20 2022-06-21 Neuroenhancement Lab, LLC System and method for inducing sleep by transplanting mental states
CN109199400B (en) * 2018-09-10 2021-08-31 中山大学 Blood glucose electrochemical sensor based on microneedle array
CA3112564A1 (en) 2018-09-14 2020-03-19 Neuroenhancement Lab, LLC System and method of improving sleep
US11285482B2 (en) 2018-09-21 2022-03-29 Lockheed Martin Corporation Molecular sensing device
US11786694B2 (en) 2019-05-24 2023-10-17 NeuroLight, Inc. Device, method, and app for facilitating sleep
USD1002852S1 (en) 2019-06-06 2023-10-24 Abbott Diabetes Care Inc. Analyte sensor device
WO2020256282A1 (en) * 2019-06-21 2020-12-24 울산과학기술원 Resonator assembly for biometric sensing and biosensor using electromagnetic waves
EP4013305A4 (en) * 2019-08-12 2023-08-23 Efferent Labs, Inc. Wearable devices for monitoring physiological changes and methods of use
CN110824157B (en) * 2019-11-14 2023-03-31 广州科方生物技术股份有限公司 Method for quickly separating red blood cells for immunochromatography detection kit
TWI746015B (en) * 2019-12-09 2021-11-11 財團法人工業技術研究院 Wearable measurement device and method of measuring a biological target using the same
KR102309531B1 (en) * 2020-01-29 2021-10-07 성균관대학교산학협력단 Microfluidic device for detecting biomolecules in sweat and wearable biosensor patch using the same
WO2021163347A1 (en) * 2020-02-11 2021-08-19 Life Patch International Wearable patches for sports
IL299194A (en) * 2020-06-16 2023-02-01 Liron Ben Bashat Bergman Whole blood sampling and monitoring device, method and software
CN111657875B (en) * 2020-07-09 2021-01-29 深圳市则成电子股份有限公司 Blood oxygen testing method, device and storage medium thereof
US11904314B2 (en) * 2020-07-30 2024-02-20 Wainamics, Inc. System and self-metering cartridges for point of care bioassays
US11898197B2 (en) 2020-07-30 2024-02-13 Wainamics, Inc. System and self-metering cartridges for point of care bioassays
US11803180B2 (en) 2020-10-15 2023-10-31 Ethernovia Inc. Determining diagnostic coverage for achieving functional safety
US11734966B1 (en) 2020-10-15 2023-08-22 Ethernovia Inc. Recursive system layer analysis for achieving functional safety
WO2022109390A1 (en) * 2020-11-22 2022-05-27 Gattaco Inc. Sample transfer devices, and components and methods thereof
USD999913S1 (en) 2020-12-21 2023-09-26 Abbott Diabetes Care Inc Analyte sensor inserter
CA3219530A1 (en) * 2021-05-19 2022-11-24 Namal NAWANA Self-contained dermal patch for blood analysis
CN113576450A (en) * 2021-07-16 2021-11-02 广州医科大学附属第一医院 Cough monitoring device and cough monitoring system
US11877848B2 (en) 2021-11-08 2024-01-23 Satio, Inc. Dermal patch for collecting a physiological sample
WO2023085780A1 (en) * 2021-11-09 2023-05-19 엘지전자 주식회사 Mobile terminal
CN116824579B (en) * 2023-06-27 2023-12-22 长沙金域医学检验实验室有限公司 Method and device for detecting yarrowia pneumocystis based on direct immunofluorescence staining

Family Cites Families (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3654090A (en) 1968-09-24 1972-04-04 Organon Method for the determination of antigens and antibodies
US3940475A (en) 1970-06-11 1976-02-24 Biological Developments, Inc. Radioimmune method of assaying quantitatively for a hapten
US3874852A (en) 1974-07-05 1975-04-01 Coulter Diagnostics Inc Reagent and method for determining leukocytes and hemoglobin in the blood
CA1056746A (en) 1974-09-06 1979-06-19 Chung J. Lai Biologically active membrane material
US4286963A (en) 1979-11-23 1981-09-01 Coulter Electronics, Inc. Differential lymphoid-myeloid determination of leukocytes in whole blood
US4346018A (en) 1980-06-16 1982-08-24 Coulter Electronics, Inc. Multi-purpose blood diluent and lysing agent for differential determination of lymphoid-myeloid population of leukocytes
US4846182A (en) 1982-01-11 1989-07-11 Medtronic, Inc. Method of preparing a fluid absorbent quantitative test device
US4528274A (en) 1982-07-06 1985-07-09 Coulter Electronics, Inc. Multi-purpose blood diluent and lysing agent for differential determination of lymphoid-myeloid population of leukocytes
US4485175A (en) 1983-01-03 1984-11-27 Coulter Electronics, Inc. Method for three-volume differential determination of lymphocyte, monocyte and granulocyte populations of leukocytes
US4751179A (en) 1984-05-31 1988-06-14 Coulter Electronics, Inc. Method and reagents for differential determination of four populations of leukocytes in blood
US4732153A (en) 1984-07-18 1988-03-22 Michael Phillips Transdermal dosimeter
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US5114864A (en) * 1986-06-25 1992-05-19 Trustees Of Tufts College Fiber optic sensors, apparatus, and detection methods using fluid erodible controlled release polymers for delivery of reagent formulations
IL85532A (en) 1987-03-13 1992-03-29 Coulter Electronics Method and lytic reagent system for isolation,identification and/or analysis of leukocytes from whole blood samples
US4821733A (en) 1987-08-18 1989-04-18 Dermal Systems International Transdermal detection system
US5465713A (en) 1988-09-08 1995-11-14 Sudor Partners Energy-assisted transdermal collection patch for accelerated analyte collection and method of use
US5231015A (en) 1989-10-18 1993-07-27 Eastman Kodak Company Methods of extracting nucleic acids and pcr amplification without using a proteolytic enzyme
US5458140A (en) * 1993-11-15 1995-10-17 Non-Invasive Monitoring Company (Nimco) Enhancement of transdermal monitoring applications with ultrasound and chemical enhancers
US5443080A (en) 1993-12-22 1995-08-22 Americate Transtech, Inc. Integrated system for biological fluid constituent analysis
US5787885A (en) * 1994-10-13 1998-08-04 Lemelson; Jerome H. Body fluid analysis system
US6027459A (en) 1996-12-06 2000-02-22 Abbott Laboratories Method and apparatus for obtaining blood for diagnostic tests
JPH10305016A (en) 1997-05-08 1998-11-17 Casio Comput Co Ltd Behavior information providing system
EP1056396B1 (en) 1998-02-17 2005-11-09 Abbott Laboratories Interstitial fluid collection and monitoring device
US6479015B1 (en) 1998-03-03 2002-11-12 Pepex Biomedical, Llc Apparatus for monitoring a level of a chemical species in a body fluid
PT1077634E (en) 1998-05-13 2003-12-31 Cygnus Therapeutic Systems MONITORING OF PHYSIOLOGICAL SUBSTANCES TO BE ANALYZED
PT1053043E (en) 1998-05-13 2002-11-29 Cygnus Therapeutic Systems COLLECTION ASSEMBLIES FOR TRANSDERMIC SAMPLING SYSTEMS
JP2002517300A (en) * 1998-06-10 2002-06-18 ジョージア テック リサーチ コーポレイション Microneedle devices and methods of manufacture and uses thereof
DE69937738D1 (en) * 1998-07-21 2008-01-24 Altea Therapeutics Corp METHOD AND DEVICE FOR THE CONTINUOUS MONITORING OF AN ANALYTE
DE19848112C2 (en) * 1998-10-19 2001-12-13 Meinhard Knoll Minimally invasive sensor system
US6424847B1 (en) * 1999-02-25 2002-07-23 Medtronic Minimed, Inc. Glucose monitor calibration methods
US20040200909A1 (en) * 1999-05-28 2004-10-14 Cepheid Apparatus and method for cell disruption
US6379324B1 (en) * 1999-06-09 2002-04-30 The Procter & Gamble Company Intracutaneous microneedle array apparatus
US6223074B1 (en) 1999-08-10 2001-04-24 Thuris Corporation Method and computer program product for assessing neurological conditions and treatments using evoked response potentials
US6251083B1 (en) 1999-09-07 2001-06-26 Amira Medical Interstitial fluid methods and devices for determination of an analyte in the body
US6835184B1 (en) * 1999-09-24 2004-12-28 Becton, Dickinson And Company Method and device for abrading skin
US7171251B2 (en) 2000-02-01 2007-01-30 Spo Medical Equipment Ltd. Physiological stress detector device and system
US6887202B2 (en) 2000-06-01 2005-05-03 Science Applications International Corporation Systems and methods for monitoring health and delivering drugs transdermally
US7351376B1 (en) * 2000-06-05 2008-04-01 California Institute Of Technology Integrated active flux microfluidic devices and methods
WO2002005702A2 (en) * 2000-07-18 2002-01-24 Healthetech, Inc. Closed loop glycemic index system
US6553244B2 (en) 2000-08-18 2003-04-22 Cygnus, Inc. Analyte monitoring device alarm augmentation system
US6585646B2 (en) 2000-11-29 2003-07-01 Hermetic Diagnostics, Inc. Screening test and procedure using skin patches
GB0030929D0 (en) * 2000-12-19 2001-01-31 Inverness Medical Ltd Analyte measurement
US6453928B1 (en) * 2001-01-08 2002-09-24 Nanolab Ltd. Apparatus, and method for propelling fluids
CN1306619C (en) * 2001-03-30 2007-03-21 加利福尼亚大学董事会 Methods of fabricating nanostructures and nanowires and devices fabricated therefrom
EP1262559A1 (en) 2001-06-01 2002-12-04 SIRS-Lab GmbH Dermal patch for detecting lactate
US20030208113A1 (en) * 2001-07-18 2003-11-06 Mault James R Closed loop glycemic index system
US20040094733A1 (en) * 2001-08-31 2004-05-20 Hower Robert W. Micro-fluidic system
US6723077B2 (en) 2001-09-28 2004-04-20 Hewlett-Packard Development Company, L.P. Cutaneous administration system
US7004928B2 (en) * 2002-02-08 2006-02-28 Rosedale Medical, Inc. Autonomous, ambulatory analyte monitor or drug delivery device
US7364896B2 (en) * 2002-10-31 2008-04-29 Agilent Technologies, Inc. Test strips including flexible array substrates and method of hybridization
JP2007503958A (en) * 2003-09-03 2007-03-01 ライフパッチ インターナショナル，インコーポレイテッド Personal diagnostic equipment and related methods

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9480421B2 (en) 2005-09-30 2016-11-01 Abbott Diabetes Care Inc. Integrated introducer and transmitter assembly and methods of use
US9398882B2 (en) 2005-09-30 2016-07-26 Abbott Diabetes Care Inc. Method and apparatus for providing analyte sensor and data processing device
US9521968B2 (en) 2005-09-30 2016-12-20 Abbott Diabetes Care Inc. Analyte sensor retention mechanism and methods of use
USD979766S1 (en) 2005-09-30 2023-02-28 Abbott Diabetes Care Inc. Analyte sensor device
US9332933B2 (en) 2005-12-28 2016-05-10 Abbott Diabetes Care Inc. Method and apparatus for providing analyte sensor insertion
US8852101B2 (en) 2005-12-28 2014-10-07 Abbott Diabetes Care Inc. Method and apparatus for providing analyte sensor insertion
US8862198B2 (en) 2006-09-10 2014-10-14 Abbott Diabetes Care Inc. Method and system for providing an integrated analyte sensor insertion device and data processing unit
US9259175B2 (en) 2006-10-23 2016-02-16 Abbott Diabetes Care, Inc. Flexible patch for fluid delivery and monitoring body analytes
US9402544B2 (en) 2009-02-03 2016-08-02 Abbott Diabetes Care Inc. Analyte sensor and apparatus for insertion of the sensor
US9351669B2 (en) 2009-09-30 2016-05-31 Abbott Diabetes Care Inc. Interconnect for on-body analyte monitoring device
US9265453B2 (en) 2010-03-24 2016-02-23 Abbott Diabetes Care Inc. Medical device inserters and processes of inserting and using medical devices
US9572534B2 (en) 2010-06-29 2017-02-21 Abbott Diabetes Care Inc. Devices, systems and methods for on-skin or on-body mounting of medical devices
US9402570B2 (en) 2011-12-11 2016-08-02 Abbott Diabetes Care Inc. Analyte sensor devices, connections, and methods

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US9993189B2 (en) 2018-06-12
US20180344230A1 (en) 2018-12-06
CN1874720A (en) 2006-12-06
EP1670356A1 (en) 2006-06-21
US20240090804A1 (en) 2024-03-21
KR101165102B1 (en) 2012-07-12
US20160066828A1 (en) 2016-03-10
KR20060123103A (en) 2006-12-01
US9133024B2 (en) 2015-09-15
WO2005084534A1 (en) 2005-09-15
US20160058354A1 (en) 2016-03-03
US20050106713A1 (en) 2005-05-19
JP2007503958A (en) 2007-03-01
CN1874720B (en) 2010-11-17
AU2004317007A2 (en) 2005-09-15
US11737694B2 (en) 2023-08-29
CA2537796C (en) 2013-12-03
SG146630A1 (en) 2008-10-30
CN102018496A (en) 2011-04-20
CA2537796A1 (en) 2005-09-15
BRPI0414067A (en) 2006-10-24
AU2004317007A1 (en) 2005-09-15

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