WO2005086617A3 - Conformationally flexible cationic conjugated polymers - Google Patents

Conformationally flexible cationic conjugated polymers Download PDF

Info

Publication number
WO2005086617A3
WO2005086617A3 PCT/US2004/030605 US2004030605W WO2005086617A3 WO 2005086617 A3 WO2005086617 A3 WO 2005086617A3 US 2004030605 W US2004030605 W US 2004030605W WO 2005086617 A3 WO2005086617 A3 WO 2005086617A3
Authority
WO
WIPO (PCT)
Prior art keywords
polymers
conformationally flexible
cationic conjugated
conjugated polymers
flexible cationic
Prior art date
Application number
PCT/US2004/030605
Other languages
French (fr)
Other versions
WO2005086617A2 (en
Inventor
Guillermo C Bazan
Bin Liu
Original Assignee
Univ California
Guillermo C Bazan
Bin Liu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ California, Guillermo C Bazan, Bin Liu filed Critical Univ California
Priority to AU2004317085A priority Critical patent/AU2004317085A1/en
Priority to EP04821601.4A priority patent/EP1673410B1/en
Priority to CA2531568A priority patent/CA2531568C/en
Priority to EP10013114.3A priority patent/EP2325253B1/en
Publication of WO2005086617A2 publication Critical patent/WO2005086617A2/en
Publication of WO2005086617A3 publication Critical patent/WO2005086617A3/en

Links

Classifications

    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01BCABLES; CONDUCTORS; INSULATORS; SELECTION OF MATERIALS FOR THEIR CONDUCTIVE, INSULATING OR DIELECTRIC PROPERTIES
    • H01B1/00Conductors or conductive bodies characterised by the conductive materials; Selection of materials as conductors
    • H01B1/06Conductors or conductive bodies characterised by the conductive materials; Selection of materials as conductors mainly consisting of other non-metallic substances
    • H01B1/12Conductors or conductive bodies characterised by the conductive materials; Selection of materials as conductors mainly consisting of other non-metallic substances organic substances
    • H01B1/122Ionic conductors
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G61/00Macromolecular compounds obtained by reactions forming a carbon-to-carbon link in the main chain of the macromolecule
    • C08G61/02Macromolecular compounds containing only carbon atoms in the main chain of the macromolecule, e.g. polyxylylenes
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G61/00Macromolecular compounds obtained by reactions forming a carbon-to-carbon link in the main chain of the macromolecule
    • C08G61/02Macromolecular compounds containing only carbon atoms in the main chain of the macromolecule, e.g. polyxylylenes
    • C08G61/10Macromolecular compounds containing only carbon atoms in the main chain of the macromolecule, e.g. polyxylylenes only aromatic carbon atoms, e.g. polyphenylenes
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G61/00Macromolecular compounds obtained by reactions forming a carbon-to-carbon link in the main chain of the macromolecule
    • C08G61/12Macromolecular compounds containing atoms other than carbon in the main chain of the macromolecule
    • C08G61/122Macromolecular compounds containing atoms other than carbon in the main chain of the macromolecule derived from five- or six-membered heterocyclic compounds, other than imides
    • C08G61/123Macromolecular compounds containing atoms other than carbon in the main chain of the macromolecule derived from five- or six-membered heterocyclic compounds, other than imides derived from five-membered heterocyclic compounds
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G61/00Macromolecular compounds obtained by reactions forming a carbon-to-carbon link in the main chain of the macromolecule
    • C08G61/12Macromolecular compounds containing atoms other than carbon in the main chain of the macromolecule
    • C08G61/122Macromolecular compounds containing atoms other than carbon in the main chain of the macromolecule derived from five- or six-membered heterocyclic compounds, other than imides
    • C08G61/123Macromolecular compounds containing atoms other than carbon in the main chain of the macromolecule derived from five- or six-membered heterocyclic compounds, other than imides derived from five-membered heterocyclic compounds
    • C08G61/126Macromolecular compounds containing atoms other than carbon in the main chain of the macromolecule derived from five- or six-membered heterocyclic compounds, other than imides derived from five-membered heterocyclic compounds with a five-membered ring containing one sulfur atom in the ring
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G73/00Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
    • C08G73/02Polyamines
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G73/00Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
    • C08G73/06Polycondensates having nitrogen-containing heterocyclic rings in the main chain of the macromolecule
    • C08G73/08Polyhydrazides; Polytriazoles; Polyaminotriazoles; Polyoxadiazoles
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00Libraries per se, e.g. arrays, mixtures
    • C40B40/04Libraries containing only organic compounds

Abstract

Methods, compositions and articles of manufacture involving cationic conjugated conformationally flexible polymers are provided. A method for the synthesis of cationic water-soluble polymers with linkages along the polymer main chain structure which disrupt the ability of the polymers to form extended-rod structures is provided. Such polymers may serve in the fabrication of novel optoelectronic devices and in the development of highly efficient biosensors. The invention further relates to the application of these polymers in assay methods.
PCT/US2004/030605 2003-09-17 2004-09-17 Conformationally flexible cationic conjugated polymers WO2005086617A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
AU2004317085A AU2004317085A1 (en) 2003-09-17 2004-09-17 Conformationally flexible cationic conjugated polymers
EP04821601.4A EP1673410B1 (en) 2003-09-17 2004-09-17 Conformationally flexible cationic conjugated polymers
CA2531568A CA2531568C (en) 2003-09-17 2004-09-17 Conformationally flexible cationic conjugated polymers
EP10013114.3A EP2325253B1 (en) 2003-09-17 2004-09-17 Conformationally flexible cationic conjugated polymers

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/666,333 US7144950B2 (en) 2003-09-17 2003-09-17 Conformationally flexible cationic conjugated polymers
US10/666,333 2003-09-17

Publications (2)

Publication Number Publication Date
WO2005086617A2 WO2005086617A2 (en) 2005-09-22
WO2005086617A3 true WO2005086617A3 (en) 2006-02-23

Family

ID=34274710

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/030605 WO2005086617A2 (en) 2003-09-17 2004-09-17 Conformationally flexible cationic conjugated polymers

Country Status (6)

Country Link
US (3) US7144950B2 (en)
EP (2) EP1673410B1 (en)
AU (1) AU2004317085A1 (en)
CA (3) CA2787367C (en)
ES (1) ES2870849T3 (en)
WO (1) WO2005086617A2 (en)

Families Citing this family (63)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1080162B1 (en) 1998-05-05 2004-03-10 Massachusetts Institute Of Technology Emissive polymers and devices incorporating these polymers
US20050147534A1 (en) 1998-05-05 2005-07-07 Massachusetts Institute Of Technology Emissive sensors and devices incorporating these sensors
US10001475B2 (en) 2002-06-20 2018-06-19 The Regents Of The University Of California Light harvesting multichromophore compositions and methods of using the same
US9371559B2 (en) 2002-06-20 2016-06-21 The Regents Of The University Of California Compositions for detection and analysis of polynucleotides using light harvesting multichromophores
EP2316971A1 (en) 2002-08-26 2011-05-04 The Regents of the University of California Methods and compositions for detection and analysis of polynucleotides using light harvesting multichromophores
SG111090A1 (en) * 2002-10-25 2005-05-30 Agency Science Tech & Res Cationic water-soluble conjugated polymers and their precursors
DE112004001737B4 (en) * 2003-09-17 2016-08-11 The Regents Of The University Of California A process comprising soluble, conjugated polymers for forming adjacent layers on a substrate or adding a polymer layer to a substrate, a multilayer electronic device and use in electronic components
US7351358B2 (en) 2004-03-17 2008-04-01 E.I. Du Pont De Nemours And Company Water dispersible polypyrroles made with polymeric acid colloids for electronics applications
WO2006029231A1 (en) * 2004-09-03 2006-03-16 The Regents Of The University Of California Soluble conjugated polymers
JP5909314B2 (en) * 2004-09-03 2016-04-26 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア Methods and devices using soluble conjugated polymers
US8617819B2 (en) 2004-09-17 2013-12-31 Massachusetts Institute Of Technology Polymers for analyte detection
US7811755B2 (en) * 2005-01-10 2010-10-12 The Regents Of The University Of California Methods and articles for strand-specific polynucleotide detection with cationic multichromophores
US7897684B2 (en) 2005-01-10 2011-03-01 The Regents Of The University Of California Conjugated polymers suitable for strand-specific polynucleotide detection in homogeneous and solid state assays
US7666594B2 (en) 2005-01-31 2010-02-23 The Regents Of The University Of California Methods for assaying a sample for an aggregant
KR101294892B1 (en) * 2005-06-27 2013-08-09 이 아이 듀폰 디 네모아 앤드 캄파니 Electrically Conductive Polymer Compositions
US7704751B2 (en) * 2006-09-18 2010-04-27 3M Innovative Properties Company Polymeric fluorescent chemical sensor
US8283423B2 (en) 2006-09-29 2012-10-09 Massachusetts Institute Of Technology Polymer synthetic technique
US8802447B2 (en) * 2006-10-05 2014-08-12 Massachusetts Institute Of Technology Emissive compositions with internal standard and related techniques
EP2164988B1 (en) 2006-10-06 2016-02-17 Sirigen Inc. Fluorescent methods and materials for directed biomarker signal amplification
US20090215189A1 (en) 2006-10-27 2009-08-27 Massachusetts Institute Of Technology Sensor of species including toxins and chemical warfare agents
US20080191172A1 (en) * 2006-12-29 2008-08-14 Che-Hsiung Hsu High work-function and high conductivity compositions of electrically conducting polymers
WO2008143731A2 (en) * 2007-03-01 2008-11-27 University Of Florida Research Foundation, Inc. Surface grafted conjugated polymers
US9293708B2 (en) 2011-06-17 2016-03-22 The Regents Of The University Of California Regioregular pyridal[2,1,3]thiadiazole π-conjugated copolymers for organic semiconductors
US20090137925A1 (en) * 2007-11-23 2009-05-28 Divya Cantor Impedance Spectroscopy Cervix Scanning Apparatus and Method
US20090230362A1 (en) * 2008-01-25 2009-09-17 Bazan Guillermo C Conjugated oligoelectrolyte electron transporting layers
US8848158B2 (en) * 2008-07-01 2014-09-30 Gentex Corporation Liquid crystal display device and associated liquid crystal media for use in the same
US9332973B2 (en) 2008-10-01 2016-05-10 Covidien Lp Needle biopsy device with exchangeable needle and integrated needle protection
US9782565B2 (en) 2008-10-01 2017-10-10 Covidien Lp Endoscopic ultrasound-guided biliary access system
US9186128B2 (en) 2008-10-01 2015-11-17 Covidien Lp Needle biopsy device
US11298113B2 (en) 2008-10-01 2022-04-12 Covidien Lp Device for needle biopsy with integrated needle protection
US8968210B2 (en) 2008-10-01 2015-03-03 Covidien LLP Device for needle biopsy with integrated needle protection
SG177355A1 (en) 2009-06-26 2012-02-28 Sirigen Inc Signal amplified biological detection with conjugated polymers
WO2011053971A2 (en) * 2009-11-02 2011-05-05 Fina Biosolutions, Llc Method for enhancing the sensitivity of antibody based assays
US8575303B2 (en) 2010-01-19 2013-11-05 Sirigen Group Limited Reagents for directed biomarker signal amplification
US20120015344A1 (en) * 2010-05-14 2012-01-19 1. Board of Trustees of MICHIGAN STATE UNIVERSITY Methods, compositions, and apparatus for the detection of viral strains
WO2012009472A2 (en) 2010-07-13 2012-01-19 Stc.Unm Structure, synthesis, and applications for oligo phenylene ethynylenes (opes)
US10186661B2 (en) * 2015-03-02 2019-01-22 The Regents Of The University Of California Blade coating on nanogrooved substrates yielding aligned thin films of high mobility semiconducting polymers
US9549549B2 (en) 2011-08-03 2017-01-24 Stc.Unm Antimicrobial materials and methods
CN102384978A (en) * 2011-08-30 2012-03-21 南京邮电大学 Fluorescence detection method for detecting desoxyribonucleic acid binding protein
CN102627964B (en) * 2012-03-23 2014-04-02 上海师范大学 Water-soluble cationic conjugated microporous polymer phosphorescent probe and preparation method thereof
WO2015050869A1 (en) 2013-10-02 2015-04-09 Becton Dickinson And Company Polymersome encapsulation of hydrophobic fluorescent polymers
US9968698B2 (en) 2013-11-08 2018-05-15 Stc. Unm Charged singlet-oxygen sensitizers and oppositely-charged surfactants
US10533991B2 (en) 2014-03-14 2020-01-14 Stc.Unm P-phenylene ethynylene compounds as bioactive and detection agents
WO2016115362A1 (en) 2015-01-14 2016-07-21 Whitten David G Conjugated polyelectrolytes and methods of using the same
JP2018509621A (en) 2015-03-12 2018-04-05 ベクトン・ディキンソン・アンド・カンパニーBecton, Dickinson And Company Ultraviolet absorbing polymer dye and method of using the same
WO2016191004A1 (en) 2015-05-26 2016-12-01 Becton, Dickinson And Company Methods and systems for high resolution fluorescence microscopy of polymeric dye-labeled samples using polarized light
CN105399341B (en) * 2015-11-24 2018-03-27 中国工程物理研究院化工材料研究所 Individual layer fluorenes class conjugated polymer film based on poly-dopamine modified lithium inorganic substrate and its preparation method and application
ES2911298T3 (en) 2015-12-16 2022-05-18 Becton Dickinson Co Photostable fluorescent tandem polymeric dyes including luminescent metal complexes
WO2017172608A1 (en) 2016-03-28 2017-10-05 Aat Bioquest, Inc. Polyfluoreno[4,5-cde]oxepine conjugates and their use in methods of analyte detection
BR112018071026B1 (en) 2016-04-15 2023-04-11 Beckman Coulter, Inc WATER-SOLUBLE FLUORESCENT POLYMER AND METHOD FOR DETECTING AN ANALYTE FROM A SAMPLE
US10545137B2 (en) 2016-04-22 2020-01-28 Becton, Dickinson And Company Multiplex polymeric dye devices and methods for using the same
CN109661439A (en) 2016-07-07 2019-04-19 贝克顿·迪金森公司 The aqueous solvent conjugated polymer to fluoresce
WO2018009861A1 (en) 2016-07-08 2018-01-11 Biolegend Substituted polyfluorene compounds
WO2018013389A1 (en) 2016-07-11 2018-01-18 Becton, Dickinson And Company Blue-excitable water-solvated polymeric dyes
CN106448826A (en) * 2016-11-03 2017-02-22 上海安费诺永亿通讯电子有限公司 Electronic element, antenna and transmission line
CA3039672A1 (en) 2016-12-12 2018-06-21 Becton, Dickinson And Company Water-soluble polymeric dyes
US10772851B2 (en) 2017-02-03 2020-09-15 Aaron Kurt Neumann Treatment and prevention of fungal infections
US11320437B2 (en) 2017-02-08 2022-05-03 Becton, Dickinson And Company Dried dye reagent devices and methods for making and using the same
EP3658648B1 (en) 2017-07-28 2021-10-27 BioLegend, Inc. Conjugated polymers and methods of use
EP3732254A4 (en) 2017-12-26 2021-12-22 Becton, Dickinson and Company Deep ultraviolet-excitable water-solvated polymeric dyes
BR102019025989A2 (en) 2018-12-14 2020-06-23 Beckman Coulter, Inc. MODIFICATION OF POLYMERIC DYES AND APPLICATIONS
US11220628B2 (en) 2019-02-20 2022-01-11 Aat Bioquest, Inc. Condensed polycyclic conjugated polymers and their use for biological detection
US20220206020A1 (en) * 2019-04-24 2022-06-30 Cornell University Systems, compositions, and methods for evaluating biomechanical properties of cells

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6350431B1 (en) * 1997-04-29 2002-02-26 Nycomed Imaging As Compounds

Family Cites Families (72)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US4950587A (en) 1988-09-02 1990-08-21 Eastman Kodak Company J-aggregating dye polymers as spectral sensitizers for silver halide photographic compositions
US5998135A (en) 1989-02-24 1999-12-07 Enzo Diagnostics, Inc. Energy transfer hybridization assay using intercalators and lanthanide metals
US4948843A (en) 1989-05-30 1990-08-14 Eastman Kodak Company Dye polymer/sol-gel composites
US5143854A (en) 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
US5763162A (en) 1990-03-14 1998-06-09 The Regents Of University Of California Multichromophore fluorescent DNA intercalation complexes
GB2276169A (en) 1990-07-05 1994-09-21 Celltech Ltd Antibodies specific for carcinoembryonic antigen
ES2155822T3 (en) 1990-12-06 2001-06-01 Affymetrix Inc COMPOUNDS AND ITS USE IN A BINARY SYNTHESIS STRATEGY.
US5408109A (en) 1991-02-27 1995-04-18 The Regents Of The University Of California Visible light emitting diodes fabricated from soluble semiconducting polymers
US5384261A (en) 1991-11-22 1995-01-24 Affymax Technologies N.V. Very large scale immobilized polymer synthesis using mechanically directed flow paths
AU675054B2 (en) 1991-11-22 1997-01-23 Affymetrix, Inc. Combinatorial strategies for polymer synthesis
US5413865A (en) * 1992-01-31 1995-05-09 Central Glass Company, Limited Water-repellent metal oxide film and method of forming same on glass substrate
US5288514A (en) 1992-09-14 1994-02-22 The Regents Of The University Of California Solid phase and combinatorial synthesis of benzodiazepine compounds on a solid support
US5536820A (en) 1993-02-26 1996-07-16 E. I. Du Pont De Nemours And Company Avidin-binding azo reagents
AU7331794A (en) 1993-07-13 1995-02-13 Abbott Laboratories Fluorescent polymer labeled conjugates and intermediates
EP0684239B1 (en) 1994-05-26 2003-12-10 Canon Kabushiki Kaisha A method for detecting a target substance in a sample, utilizing pyrylium compound
US5681702A (en) 1994-08-30 1997-10-28 Chiron Corporation Reduction of nonspecific hybridization by using novel base-pairing schemes
US6008373A (en) 1995-06-07 1999-12-28 Carnegie Mellon University Fluorescent labeling complexes with large stokes shift formed by coupling together cyanine and other fluorochromes capable of resonance energy transfer
US6117635A (en) 1996-07-16 2000-09-12 Intergen Company Nucleic acid amplification oligonucleotides with molecular energy transfer labels and methods based thereon
US5881083A (en) 1997-07-03 1999-03-09 The Regents Of The University Of California Conjugated polymers as materials for solid state laser
US6322901B1 (en) 1997-11-13 2001-11-27 Massachusetts Institute Of Technology Highly luminescent color-selective nano-crystalline materials
US5990479A (en) 1997-11-25 1999-11-23 Regents Of The University Of California Organo Luminescent semiconductor nanocrystal probes for biological applications and process for making and using such probes
KR100575407B1 (en) 1998-01-09 2006-05-03 미네소타 마이닝 앤드 매뉴팩춰링 캄파니 Enzyme-specific cleavable polynucleotide substrate and assay method
ATE239801T1 (en) 1998-01-22 2003-05-15 Luminex Corp MICROPARTICLES WITH MULTIPLE FLUORESCENCE SIGNALS
US5968762A (en) 1998-03-19 1999-10-19 The University Of Connecticut Method for detecting bacteria in a sample
EP1080162B1 (en) 1998-05-05 2004-03-10 Massachusetts Institute Of Technology Emissive polymers and devices incorporating these polymers
EP1281744B1 (en) 1998-05-05 2008-09-24 Massachusetts Institute Of Technology Emissive polymers and devices incorporating these polymers
US6263286B1 (en) 1998-08-13 2001-07-17 U.S. Genomics, Inc. Methods of analyzing polymers using a spatial network of fluorophores and fluorescence resonance energy transfer
GB9819417D0 (en) 1998-09-07 1998-10-28 Secr Defence Reaction method
DE69905832T2 (en) 1998-09-18 2004-02-05 Massachusetts Institute Of Technology, Cambridge Biological uses of semiconducting nanocrystals
US6951682B1 (en) 1998-12-01 2005-10-04 Syntrix Biochip, Inc. Porous coatings bearing ligand arrays and use thereof
US6541671B1 (en) 2002-02-13 2003-04-01 The Regents Of The University Of California Synthesis of 2H- and 13C-substituted dithanes
EP1097242A4 (en) 1999-05-05 2004-04-21 Univ California Method for detecting biological agents
EP1234182A2 (en) 1999-06-30 2002-08-28 Iris Bio Technologies Hybridization of target dna with immobilized nucleic acid analogs
EP1212458A4 (en) 1999-07-30 2005-01-05 Surromed Inc Instruments, methods and reagents for surface plasmon resonance
WO2003074738A1 (en) 2000-01-18 2003-09-12 Quantom Dot Corporation Oligonucleotide-tagged semiconductor nanocrystals for microarray and fluorescence in situ hybridization
EP1279023B1 (en) 2000-03-20 2007-02-21 Analytical Biological Services, Inc. Method for detecting an analyte by fluorescence
EP2365096A1 (en) 2000-03-22 2011-09-14 Life Technologies Corporation Methods of using semiconductor nanocrystals in bead-based nucleic acid assays
CA2409512A1 (en) 2000-05-08 2001-11-15 Qtl Biosystems Llc Improvements to the fluorescent polymer-qtl approach to biosensing
WO2001095059A2 (en) 2000-06-06 2001-12-13 Dna Sciences, Inc. A method and system for populating a database
US20020177136A1 (en) 2000-08-23 2002-11-28 Mcbranch Duncan W. Peptide nucleic acid based molecular sensors for nucleic acids
CA2441279A1 (en) 2001-03-16 2002-09-26 Qtl Biosystems, Llc Fluorescent polymer superquenching-based bioassays
AU2002252868C1 (en) 2001-04-05 2008-04-17 Infectio Diagnostic (I.D.I.), Inc. Detection of negatively charged polymers using water-soluble, cationic, polythiophene derivatives
WO2002084271A2 (en) 2001-04-16 2002-10-24 The Regents Of The University Of California Methods and sensors for luminescent and optoelectronic detection and analysis of polynucleotides
IL160519A0 (en) 2001-08-23 2004-07-25 Qtl Biosystems Llc Bio-sensing platforms for detection and quantitation of biological molecules
DE10153829A1 (en) 2001-11-05 2003-05-28 Bayer Ag Assay based on doped nanoparticles
AU2002363530A1 (en) 2001-11-07 2003-05-19 Sensor Technologies Llc Method of identifying energy transfer sensors for analytes
US20040023248A1 (en) 2001-12-07 2004-02-05 Whitehead Institiute For Biomedical Research Methods and reagents for improving nucleic acid detection
US6808542B2 (en) 2001-12-26 2004-10-26 American Dye Source, Inc. Photoluminescent markers and methods for detection of such markers
US7863038B2 (en) 2002-03-29 2011-01-04 Board Of Regents, The University Of Texas System Implantable biosensor from stratified nanostructured membranes
US20040009506A1 (en) 2002-03-29 2004-01-15 Genentech, Inc. Methods and compositions for detection and quantitation of nucleic acid analytes
SE0201468D0 (en) 2002-05-13 2002-05-13 Peter Aasberg Method of using luminescent polymers for detection of biospecific interaction
WO2003102239A2 (en) 2002-05-31 2003-12-11 Secretary, Department Of Atomic Energy Met/fret based method of target nucleic acid detection whereby the donor/acceptor moieties are on complementary strands
CN102766695A (en) 2002-06-20 2012-11-07 加州大学评议会 Methods and compositions for detection and analysis of polynucleotides using light harvesting multichromophores
EP2316971A1 (en) 2002-08-26 2011-05-04 The Regents of the University of California Methods and compositions for detection and analysis of polynucleotides using light harvesting multichromophores
SG111090A1 (en) * 2002-10-25 2005-05-30 Agency Science Tech & Res Cationic water-soluble conjugated polymers and their precursors
US20040121337A1 (en) 2002-12-19 2004-06-24 Nomadics, Inc. Luminescent polymers and methods of use thereof
CN1771335A (en) 2003-02-13 2006-05-10 加州大学评议会 Methods and compositions for detection and analysis of polynucleotide-binding protein interactions using light harvesting multichromophores
JP3912393B2 (en) 2003-08-08 2007-05-09 セイコーエプソン株式会社 Method for manufacturing organic electroluminescence device
DE112004001737B4 (en) * 2003-09-17 2016-08-11 The Regents Of The University Of California A process comprising soluble, conjugated polymers for forming adjacent layers on a substrate or adding a polymer layer to a substrate, a multilayer electronic device and use in electronic components
US7141437B2 (en) 2003-11-13 2006-11-28 Michigan Molecular Institute Solid-state colorimetric biosensors comprised of dendritic polymer networks
US7700366B2 (en) 2003-12-04 2010-04-20 Massachusetts Institute Of Technology Fluorescent, semi-conductive polymers, and devices comprising them
US7759127B2 (en) 2003-12-05 2010-07-20 Massachusetts Institute Of Technology Organic materials able to detect analytes
WO2005056827A1 (en) 2003-12-12 2005-06-23 Infectio Recherche Inc. System for charge-based detection of nucleic acids
SE0401219D0 (en) 2004-05-10 2004-05-10 Biochromix Ab Methods for detecting conformational changes or aggregation of proteins by conjugated polyelectrolytes
US8617819B2 (en) 2004-09-17 2013-12-31 Massachusetts Institute Of Technology Polymers for analyte detection
WO2007001438A2 (en) 2004-10-29 2007-01-04 Molecular Probes, Inc. Functionalized fluorescent nanocrystals, and methods for their preparation and use
US7897684B2 (en) 2005-01-10 2011-03-01 The Regents Of The University Of California Conjugated polymers suitable for strand-specific polynucleotide detection in homogeneous and solid state assays
US7811755B2 (en) 2005-01-10 2010-10-12 The Regents Of The University Of California Methods and articles for strand-specific polynucleotide detection with cationic multichromophores
JP4933458B2 (en) 2005-03-03 2012-05-16 ナショナル リサーチ カウンシル オブ カナダ Methods and compositions for detection and analysis of nucleic acids by signal amplification
US9852392B2 (en) 2014-02-28 2017-12-26 Nokia Technologies Oy 3D model and beacon for automatic delivery of goods
JP2016031772A (en) 2014-07-30 2016-03-07 株式会社日立ハイテクファインシステムズ Inspection method and apparatus of heat-assisted magnetic head element

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6350431B1 (en) * 1997-04-29 2002-02-26 Nycomed Imaging As Compounds

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP1673410A4 *

Also Published As

Publication number Publication date
EP2325253A2 (en) 2011-05-25
US7144950B2 (en) 2006-12-05
US20050059168A1 (en) 2005-03-17
ES2870849T3 (en) 2021-10-27
EP2325253B1 (en) 2021-04-21
CA2876885C (en) 2018-11-06
AU2004317085A1 (en) 2005-09-22
CA2531568C (en) 2012-11-20
EP1673410B1 (en) 2016-06-15
US7914984B2 (en) 2011-03-29
US20110183439A1 (en) 2011-07-28
EP2325253A3 (en) 2011-06-01
CA2787367C (en) 2015-04-14
WO2005086617A2 (en) 2005-09-22
EP1673410A2 (en) 2006-06-28
CA2876885A1 (en) 2005-09-22
CA2531568A1 (en) 2005-09-22
EP1673410A4 (en) 2008-06-04
US20070088130A1 (en) 2007-04-19
CA2787367A1 (en) 2005-09-22
US9159465B2 (en) 2015-10-13

Similar Documents

Publication Publication Date Title
WO2005086617A3 (en) Conformationally flexible cationic conjugated polymers
EP3981819A3 (en) Novel reagents for directed biomarker signal amplification
WO2002085952A3 (en) Modified polymers with a high proportion of cis-position double bonds, method for the production and use thereof
WO2006138572A3 (en) Conjugates having a degradable linkage and polymeric reagents useful in preparing such conjugates
WO2008013694A3 (en) Slag concrete manufactured aggregate
WO2006047419A3 (en) Heterobifunctional poly(ethylene glycol) and uses thereof
WO2005084303A3 (en) Interferon-beta polymer conjugates
WO2007012013A3 (en) Polymer conjugates to therapeutic agents via an si-n and/or an si-o linkage
WO2007102956A3 (en) Bi-tapered reinforcing fibers
WO2006092271A3 (en) Water-absorbent polymer structures based on renewable resources and method for producing said structures
WO2007031965A3 (en) Lotioned fibrous structures
WO2006115547A3 (en) Dendritic polymers with enhanced amplification and interior functionality
WO2005107427A3 (en) Patterned fibrous structures
BRPI0819506A2 (en) "polymerizable ethylenically unsaturated macromonomer, macromonomer production process, addition polymer and coating composition"
WO2003084982A3 (en) Functionalized compositions for improved immobilization
EP1709699B8 (en) Conjugated polymers, representation thereof, and use of the same
WO2010096444A3 (en) Photochemical cross-linkable polymers, methods of making photochemical cross-linkable polymers, and methods of using photochemical cross-linkable polymers
DE602004023774D1 (en) Conductive composition
WO2005086826A3 (en) Procedure for preparing redox-active polymers on surfaces
WO2008051221A3 (en) Compositions and methods for imparting oil repellency and/or water repellency
WO2005121185A8 (en) Process for preparation of polysaccharide-grafted polymer particles
WO2007066353A3 (en) Novel polymers of 3,4-propylenedioxythiophene derivatives with pendant functional groups
WO2006118875A3 (en) High molecular weight compact structured polymers, methods of making and using
ATE452620T1 (en) PARTICLES FUNCTIONALIZED WITH ORGANIC COMPOUNDS
WO2001083866A3 (en) Salt-sensitive, water-dispersible polymer composition

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BW BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE EG ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NA NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SY TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): BW GH GM KE LS MW MZ NA SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LU MC NL PL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

WWE Wipo information: entry into national phase

Ref document number: 2004821601

Country of ref document: EP

ENP Entry into the national phase

Ref document number: 2531568

Country of ref document: CA

WWE Wipo information: entry into national phase

Ref document number: 2004317085

Country of ref document: AU

ENP Entry into the national phase

Ref document number: 2004317085

Country of ref document: AU

Date of ref document: 20040917

Kind code of ref document: A

WWP Wipo information: published in national office

Ref document number: 2004317085

Country of ref document: AU

WWP Wipo information: published in national office

Ref document number: 2004821601

Country of ref document: EP