WO2005107946A3 - Device for the production of microdroplets by means of liquid ejection and method of producing one such device - Google Patents

Device for the production of microdroplets by means of liquid ejection and method of producing one such device Download PDF

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Publication number
WO2005107946A3
WO2005107946A3 PCT/FR2005/000908 FR2005000908W WO2005107946A3 WO 2005107946 A3 WO2005107946 A3 WO 2005107946A3 FR 2005000908 W FR2005000908 W FR 2005000908W WO 2005107946 A3 WO2005107946 A3 WO 2005107946A3
Authority
WO
WIPO (PCT)
Prior art keywords
plates
microdroplets
production
liquid ejection
deformable seal
Prior art date
Application number
PCT/FR2005/000908
Other languages
French (fr)
Other versions
WO2005107946A2 (en
Inventor
Brice Lopez
Original Assignee
Brice Lopez
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Brice Lopez filed Critical Brice Lopez
Priority to EP05757262A priority Critical patent/EP1765499A2/en
Publication of WO2005107946A2 publication Critical patent/WO2005107946A2/en
Publication of WO2005107946A3 publication Critical patent/WO2005107946A3/en

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B17/00—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups
    • B05B17/04—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods
    • B05B17/06—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations
    • B05B17/0607—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations generated by electrical means, e.g. piezoelectric transducers
    • B05B17/0638—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations generated by electrical means, e.g. piezoelectric transducers spray being produced by discharging the liquid or other fluent material through a plate comprising a plurality of orifices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/0241—Drop counters; Drop formers
    • B01L3/0268—Drop counters; Drop formers using pulse dispensing or spraying, eg. inkjet type, piezo actuated ejection of droplets from capillaries
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B17/00—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups
    • B05B17/04—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods
    • B05B17/06—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations
    • B05B17/0607—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations generated by electrical means, e.g. piezoelectric transducers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B41—PRINTING; LINING MACHINES; TYPEWRITERS; STAMPS
    • B41J—TYPEWRITERS; SELECTIVE PRINTING MECHANISMS, i.e. MECHANISMS PRINTING OTHERWISE THAN FROM A FORME; CORRECTION OF TYPOGRAPHICAL ERRORS
    • B41J2/00—Typewriters or selective printing mechanisms characterised by the printing or marking process for which they are designed
    • B41J2/005—Typewriters or selective printing mechanisms characterised by the printing or marking process for which they are designed characterised by bringing liquid or particles selectively into contact with a printing material
    • B41J2/01—Ink jet
    • B41J2/135—Nozzles
    • B41J2/14—Structure thereof only for on-demand ink jet heads
    • B41J2/14201—Structure of print heads with piezoelectric elements
    • B41J2/14233—Structure of print heads with piezoelectric elements of film type, deformed by bending and disposed on a diaphragm
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B41—PRINTING; LINING MACHINES; TYPEWRITERS; STAMPS
    • B41J—TYPEWRITERS; SELECTIVE PRINTING MECHANISMS, i.e. MECHANISMS PRINTING OTHERWISE THAN FROM A FORME; CORRECTION OF TYPOGRAPHICAL ERRORS
    • B41J2/00—Typewriters or selective printing mechanisms characterised by the printing or marking process for which they are designed
    • B41J2/005—Typewriters or selective printing mechanisms characterised by the printing or marking process for which they are designed characterised by bringing liquid or particles selectively into contact with a printing material
    • B41J2/01—Ink jet
    • B41J2/135—Nozzles
    • B41J2/14—Structure thereof only for on-demand ink jet heads
    • B41J2/14201—Structure of print heads with piezoelectric elements
    • B41J2/14274—Structure of print heads with piezoelectric elements of stacked structure type, deformed by compression/extension and disposed on a diaphragm
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00351—Means for dispensing and evacuation of reagents
    • B01J2219/00378—Piezo-electric or ink jet dispensers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00497—Features relating to the solid phase supports
    • B01J2219/00527—Sheets
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718—Type of compounds synthesised
    • B01J2219/0072—Organic compounds
    • B01J2219/00722—Nucleotides
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/12—Specific details about manufacturing devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0832—Geometry, shape and general structure cylindrical, tube shaped
    • B01L2300/0838—Capillaries
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0433—Moving fluids with specific forces or mechanical means specific forces vibrational forces
    • B01L2400/0439—Moving fluids with specific forces or mechanical means specific forces vibrational forces ultrasonic vibrations, vibrating piezo elements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0481—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure squeezing of channels or chambers

Abstract

The invention relates to a device for the production of microdroplets by means of liquid ejection. The inventive device consists of a sealed chamber (1) comprising a liquid inlet (2) and at least one liquid outlet (3) and, for example, an actuating piezoelectric plate (7) which causes droplets (10) to be ejected through the outlet (3). The chamber (1) is defined mainly by lower (5) and upper (6) rigid plates and an essentially-annular, thin deformable seal (4) which is disposed between the plates (5, 6) and which forms a lateral wall of the chamber (1). The piezoelectric plate (7) causes a relative movement between all of the lower (5) and upper (6) plates in terms of bending and/or translation, by compressing the deformable seal (4). According to the invention, the lower (5) and upper (6) plates are stiffer than the deformable seal (4).
PCT/FR2005/000908 2004-04-19 2005-04-14 Device for the production of microdroplets by means of liquid ejection and method of producing one such device WO2005107946A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP05757262A EP1765499A2 (en) 2004-04-19 2005-04-14 Device for the production of microdroplets by means of liquid ejection and method of producing one such device

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0404114A FR2868966B1 (en) 2004-04-19 2004-04-19 DEVICE FOR PRODUCING MICRO-DROPS BY EJECTING LIQUID AND METHOD OF MAKING SUCH A DEVICE
FR0404114 2004-04-19

Publications (2)

Publication Number Publication Date
WO2005107946A2 WO2005107946A2 (en) 2005-11-17
WO2005107946A3 true WO2005107946A3 (en) 2006-02-02

Family

ID=34944551

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FR2005/000908 WO2005107946A2 (en) 2004-04-19 2005-04-14 Device for the production of microdroplets by means of liquid ejection and method of producing one such device

Country Status (3)

Country Link
EP (1) EP1765499A2 (en)
FR (1) FR2868966B1 (en)
WO (1) WO2005107946A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102004006450B4 (en) 2004-02-05 2012-09-27 Ing. Erich Pfeiffer Gmbh metering
DE102006061506B4 (en) * 2006-12-15 2008-10-30 Ing. Erich Pfeiffer Gmbh metering
FR2963575B1 (en) 2010-08-09 2015-07-17 Renault Sa DEVICE FOR EJECTING LIQUID IN THE FORM OF MICROCHARS
WO2013155513A1 (en) * 2012-04-13 2013-10-17 President And Fellows Of Harvard College Devices and methods for in vitro aerosol delivery
EP3924107A4 (en) * 2019-02-15 2022-10-05 Cellsorter Kft. Piezoelectric micropipette
CN115007236B (en) * 2022-06-06 2024-03-29 湖北大学 Portable liquid drop manufacturing device based on centrifugal oscillation and liquid drop manufacturing method thereof

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58114965A (en) * 1981-12-28 1983-07-08 Matsushita Electric Ind Co Ltd Ink jet head
EP0095911A2 (en) * 1982-05-28 1983-12-07 Xerox Corporation Pressure pulse droplet ejector and array
US5828394A (en) * 1995-09-20 1998-10-27 The Board Of Trustees Of The Leland Stanford Junior University Fluid drop ejector and method
WO2001017669A1 (en) * 1999-09-02 2001-03-15 Hahn-Schickard Gesellschaft Für Angewandte Forschung E. V. Method and device for applying a plurality of microdroplets onto a substrate
EP1116590A1 (en) * 2000-01-11 2001-07-18 Samsung Electronics Co., Ltd. Ink-jet head device with multi-stacked PZT actuator

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4131899A (en) * 1977-02-22 1978-12-26 Burroughs Corporation Droplet generator for an ink jet printer

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58114965A (en) * 1981-12-28 1983-07-08 Matsushita Electric Ind Co Ltd Ink jet head
EP0095911A2 (en) * 1982-05-28 1983-12-07 Xerox Corporation Pressure pulse droplet ejector and array
US5828394A (en) * 1995-09-20 1998-10-27 The Board Of Trustees Of The Leland Stanford Junior University Fluid drop ejector and method
WO2001017669A1 (en) * 1999-09-02 2001-03-15 Hahn-Schickard Gesellschaft Für Angewandte Forschung E. V. Method and device for applying a plurality of microdroplets onto a substrate
EP1116590A1 (en) * 2000-01-11 2001-07-18 Samsung Electronics Co., Ltd. Ink-jet head device with multi-stacked PZT actuator

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
PATENT ABSTRACTS OF JAPAN vol. 0072, no. 21 (M - 246) 30 September 1983 (1983-09-30) *

Also Published As

Publication number Publication date
WO2005107946A2 (en) 2005-11-17
FR2868966B1 (en) 2007-08-03
FR2868966A1 (en) 2005-10-21
EP1765499A2 (en) 2007-03-28

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