WO2005121726A3 - Method and apparatus for identifying a substance - Google Patents

Method and apparatus for identifying a substance Download PDF

Info

Publication number
WO2005121726A3
WO2005121726A3 PCT/US2005/000325 US2005000325W WO2005121726A3 WO 2005121726 A3 WO2005121726 A3 WO 2005121726A3 US 2005000325 W US2005000325 W US 2005000325W WO 2005121726 A3 WO2005121726 A3 WO 2005121726A3
Authority
WO
WIPO (PCT)
Prior art keywords
measurement data
spectral measurement
spectra
substance
radiation
Prior art date
Application number
PCT/US2005/000325
Other languages
French (fr)
Other versions
WO2005121726A2 (en
Inventor
Jacob Grun
Charles K Manka
Jeffrey H Bowles
Michael R Corson
Original Assignee
Us Navy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Us Navy filed Critical Us Navy
Publication of WO2005121726A2 publication Critical patent/WO2005121726A2/en
Publication of WO2005121726A3 publication Critical patent/WO2005121726A3/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01JMEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/12Generating the spectrum; Monochromators
    • G01J3/18Generating the spectrum; Monochromators using diffraction elements, e.g. grating
    • G01J3/1804Plane gratings
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01JMEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/28Investigating the spectrum
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01JMEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/28Investigating the spectrum
    • G01J3/42Absorption spectrometry; Double beam spectrometry; Flicker spectrometry; Reflection spectrometry
    • G01J3/433Modulation spectrometry; Derivative spectrometry
    • G01J3/4338Frequency modulated spectrometry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/65Raman scattering

Abstract

A spectroscopic detector includes means for illuminating a first substance and another substance or substances present with electromagnetic radiation at a plurality of wavelengths to thereby induce the emission of radiation; means for measuring the emitted radiation at a plurality of emission wavelengths to obtain a plurality of spectral measurement data; and a processor for processing the spectral measurement data, where the processor includes a multispectral data processing algorithm or is configured for 1) combining the plurality of spectral measurement data into a composite spectrum, and 2) applying the algorithm to the composite spectrum. The spectra such as resonant and near-resonant Raman Spectra that are acquired are more complete and contain more information. A powerful multispectral analysis code such as IHPS, CHOMPS, or ENN analyzes the acquired data points, examining details of the spectra that could not be handled by traditional methods.
PCT/US2005/000325 2004-01-07 2005-01-07 Method and apparatus for identifying a substance WO2005121726A2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US60118004P 2004-01-07 2004-01-07
US53517904P 2004-01-07 2004-01-07
US60/535,179 2004-01-07
US60/601,180 2004-01-07

Publications (2)

Publication Number Publication Date
WO2005121726A2 WO2005121726A2 (en) 2005-12-22
WO2005121726A3 true WO2005121726A3 (en) 2007-05-24

Family

ID=34798845

Family Applications (2)

Application Number Title Priority Date Filing Date
PCT/US2005/000324 WO2005069193A1 (en) 2004-01-07 2005-01-07 Identifying a substance using a spectral library database
PCT/US2005/000325 WO2005121726A2 (en) 2004-01-07 2005-01-07 Method and apparatus for identifying a substance

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PCT/US2005/000324 WO2005069193A1 (en) 2004-01-07 2005-01-07 Identifying a substance using a spectral library database

Country Status (1)

Country Link
WO (2) WO2005069193A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201505297D0 (en) * 2015-03-27 2015-05-13 Univ St Andrews Pharmaceutical detection

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4629284A (en) * 1983-03-11 1986-12-16 Alliance Technique Industrielle Method and apparatus for connecting optical fibers
US4642778A (en) * 1984-03-02 1987-02-10 Indiana University Foundation Method and device for spectral reconstruction
US5479255A (en) * 1992-12-17 1995-12-26 Trw Inc. Multispectral signature extraction technique

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5123731A (en) * 1988-02-01 1992-06-23 Canon Kabushiki Kaisha Particle measuring device
US6040906A (en) * 1996-07-11 2000-03-21 Harhay; Gregory P. Resonance raman spectroscopy for identifying and quantitating biomatter, organic, and inorganic analytes

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4629284A (en) * 1983-03-11 1986-12-16 Alliance Technique Industrielle Method and apparatus for connecting optical fibers
US4642778A (en) * 1984-03-02 1987-02-10 Indiana University Foundation Method and device for spectral reconstruction
US5479255A (en) * 1992-12-17 1995-12-26 Trw Inc. Multispectral signature extraction technique

Also Published As

Publication number Publication date
WO2005121726A2 (en) 2005-12-22
WO2005069193A1 (en) 2005-07-28

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