WO2006019784A3 - Methods for repairing degraded dna - Google Patents

Methods for repairing degraded dna Download PDF

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Publication number
WO2006019784A3
WO2006019784A3 PCT/US2005/024799 US2005024799W WO2006019784A3 WO 2006019784 A3 WO2006019784 A3 WO 2006019784A3 US 2005024799 W US2005024799 W US 2005024799W WO 2006019784 A3 WO2006019784 A3 WO 2006019784A3
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WO
WIPO (PCT)
Prior art keywords
methods
degraded dna
dna
repairing degraded
repairing
Prior art date
Application number
PCT/US2005/024799
Other languages
French (fr)
Other versions
WO2006019784A2 (en
Inventor
Mark W Eshoo
Original Assignee
Isis Pharmaceuticals Inc
Mark W Eshoo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Isis Pharmaceuticals Inc, Mark W Eshoo filed Critical Isis Pharmaceuticals Inc
Publication of WO2006019784A2 publication Critical patent/WO2006019784A2/en
Publication of WO2006019784A3 publication Critical patent/WO2006019784A3/en

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay

Abstract

The present invention provides methods and kits for repair of degraded DNA which may then be used as a template for efficient amplification by a number of different amplification reactions. The method relies upon a series of enzymatic activities provided by DNA repair enzymes.
PCT/US2005/024799 2004-07-14 2005-07-13 Methods for repairing degraded dna WO2006019784A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/891,337 US7811753B2 (en) 2004-07-14 2004-07-14 Methods for repairing degraded DNA
US10/891,337 2004-07-14

Publications (2)

Publication Number Publication Date
WO2006019784A2 WO2006019784A2 (en) 2006-02-23
WO2006019784A3 true WO2006019784A3 (en) 2007-03-08

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PCT/US2005/024799 WO2006019784A2 (en) 2004-07-14 2005-07-13 Methods for repairing degraded dna

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US (2) US7811753B2 (en)
WO (1) WO2006019784A2 (en)

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