WO2006024023A3 - Nanotube sensor devices for dna detection - Google Patents

Nanotube sensor devices for dna detection Download PDF

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Publication number
WO2006024023A3
WO2006024023A3 PCT/US2005/030487 US2005030487W WO2006024023A3 WO 2006024023 A3 WO2006024023 A3 WO 2006024023A3 US 2005030487 W US2005030487 W US 2005030487W WO 2006024023 A3 WO2006024023 A3 WO 2006024023A3
Authority
WO
WIPO (PCT)
Prior art keywords
electrodes
dna sequence
target dna
nanotube
sensor devices
Prior art date
Application number
PCT/US2005/030487
Other languages
French (fr)
Other versions
WO2006024023A2 (en
Inventor
Charles Steven Joiner Jr
Jean-Christophe P Gabriel
George Gruner
Alexander Star
Original Assignee
Nanomix Inc
Charles Steven Joiner Jr
Jean-Christophe P Gabriel
George Gruner
Alexander Star
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nanomix Inc, Charles Steven Joiner Jr, Jean-Christophe P Gabriel, George Gruner, Alexander Star filed Critical Nanomix Inc
Priority to JP2007530178A priority Critical patent/JP2008511008A/en
Priority to EP05810377A priority patent/EP1781771A2/en
Publication of WO2006024023A2 publication Critical patent/WO2006024023A2/en
Publication of WO2006024023A3 publication Critical patent/WO2006024023A3/en

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/403—Cells and electrode assemblies
    • G01N27/414—Ion-sensitive or chemical field-effect transistors, i.e. ISFETS or CHEMFETS
    • G01N27/4146—Ion-sensitive or chemical field-effect transistors, i.e. ISFETS or CHEMFETS involving nanosized elements, e.g. nanotubes, nanowires
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/403—Cells and electrode assemblies
    • G01N27/414—Ion-sensitive or chemical field-effect transistors, i.e. ISFETS or CHEMFETS
    • G01N27/4145—Ion-sensitive or chemical field-effect transistors, i.e. ISFETS or CHEMFETS specially adapted for biomolecules, e.g. gate electrode with immobilised receptors

Abstract

A nanotube device is configured as an electronic sensor for a target DNA sequence. A film of nanotubes is deposited over electrodes on a substrate. A solution of single-strand DNA is prepared so as to be complementary to a target DNA sequence. The DNA solution is deposited over the electrodes, dried, and removed from the substrate except in a region between the electrodes. The resulting structure includes strands of the desired DNA sequence in direct contact with nanotubes between opposing electrodes, to form a sensor that is electrically responsive to the presence of target DNA strands. Alternative assay embodiments are described which employ linker groups to attach ssDNA probes to the nanotube sensor device.
PCT/US2005/030487 2004-08-24 2005-08-24 Nanotube sensor devices for dna detection WO2006024023A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2007530178A JP2008511008A (en) 2004-08-24 2005-08-24 Nanotube sensor device for DNA detection
EP05810377A EP1781771A2 (en) 2004-08-24 2005-08-24 Nanotube sensor devices for dna detection

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US60429304P 2004-08-24 2004-08-24
US60/604,293 2004-08-24
US62960404P 2004-11-19 2004-11-19
US60/629,604 2004-11-19

Publications (2)

Publication Number Publication Date
WO2006024023A2 WO2006024023A2 (en) 2006-03-02
WO2006024023A3 true WO2006024023A3 (en) 2009-06-04

Family

ID=35968333

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/030487 WO2006024023A2 (en) 2004-08-24 2005-08-24 Nanotube sensor devices for dna detection

Country Status (3)

Country Link
EP (1) EP1781771A2 (en)
JP (2) JP2008511008A (en)
WO (1) WO2006024023A2 (en)

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JP6473444B2 (en) * 2013-05-29 2019-02-20 シーエスアイアールＣｓｉｒ Field effect transistor and gas detector including a plurality of field effect transistors
WO2015012186A1 (en) * 2013-07-25 2015-01-29 東レ株式会社 Carbon nanotube composite, semiconductor device, and sensor using same
EP3502127B1 (en) 2013-10-09 2023-07-26 Monsanto Technology LLC Transgenic corn event mon87403 and methods for detection thereof
AU2015344977B2 (en) 2014-11-14 2021-12-23 Basf Plant Science Company Gmbh Stabilising fatty acid compositions
CN104597082B (en) * 2015-01-23 2017-02-22 清华大学 Preparation method of hybridized hierarchical structure sensitive thin-film sensing device based on two-dimensional material
CN104923777A (en) * 2015-03-18 2015-09-23 华南理工大学 High-salt-tolerance metal nanoparticle assembly and preparing method thereof
US10999986B2 (en) 2015-06-05 2021-05-11 International Rice Research Institute Increasing hybrid seed production through higher outcrossing rate in cytoplasmic male sterile rice and related materials and methods
WO2017033922A1 (en) * 2015-08-24 2017-03-02 国立大学法人 東京大学 Method of detecting target substance using field-effect transistor
KR101663910B1 (en) * 2015-09-01 2016-10-07 고려대학교 산학협력단 Sensor for detection of zinc oxide nanowire in water and method for detection of zinc oxide nanowire using the sensor
AU2017244132A1 (en) * 2016-03-30 2018-10-18 Waqas KHALID Nanostructure array based sensors for electrochemical sensing, capacitive sensing and field-emission sensing
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JP2018036154A (en) * 2016-08-31 2018-03-08 国立大学法人大阪大学 Method for electrically detecting target material, method for determining amount of the material, detection system, amount determination system, and reagent
CN106841351B (en) * 2017-02-15 2019-07-19 暨南大学 A kind of molybdenum disulfide nano sheet electrochemical sensor and the preparation method and application thereof
WO2018224861A1 (en) 2017-06-07 2018-12-13 International Rice Research Institute Increasing hybrid seed production through higher outcrossing rate in cytoplasmic male sterile gramineae plants and related materials and methods
EP3695217A1 (en) * 2017-10-10 2020-08-19 Thermo Electron Scientific Instruments LLC Carbon nanotube-based device for sensing molecular interaction
US10957626B2 (en) * 2017-12-19 2021-03-23 Thermo Electron Scientific Instruments Llc Sensor device with carbon nanotube sensor positioned on first and second substrates
US11846622B2 (en) * 2018-03-12 2023-12-19 The Trustees Of The University Of Pennsylvania Multiplexed detection of toxins using graphene-based aptasensors
JP6876661B2 (en) * 2018-09-13 2021-05-26 株式会社東芝 Organic probe and molecule detector
US20230309480A1 (en) 2020-08-18 2023-10-05 International Rice Research Institute Methods of increasing outcrossing rates in gramineae
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Also Published As

Publication number Publication date
JP2012247432A (en) 2012-12-13
WO2006024023A2 (en) 2006-03-02
EP1781771A2 (en) 2007-05-09
JP5743974B2 (en) 2015-07-01
JP2008511008A (en) 2008-04-10

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