WO2006036715A3 - Implant and pressure sensor for glaucoma treatment - Google Patents

Implant and pressure sensor for glaucoma treatment Download PDF

Info

Publication number
WO2006036715A3
WO2006036715A3 PCT/US2005/033900 US2005033900W WO2006036715A3 WO 2006036715 A3 WO2006036715 A3 WO 2006036715A3 US 2005033900 W US2005033900 W US 2005033900W WO 2006036715 A3 WO2006036715 A3 WO 2006036715A3
Authority
WO
WIPO (PCT)
Prior art keywords
stent
pressure sensor
implant
glaucoma treatment
sensor
Prior art date
Application number
PCT/US2005/033900
Other languages
French (fr)
Other versions
WO2006036715A2 (en
Inventor
David Haffner
Hosheng Tu
Gharib Morteza
Original Assignee
Glaukos Corp
David Haffner
Hosheng Tu
Gharib Morteza
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaukos Corp, David Haffner, Hosheng Tu, Gharib Morteza filed Critical Glaukos Corp
Priority to CA002581334A priority Critical patent/CA2581334A1/en
Priority to AU2005289837A priority patent/AU2005289837A1/en
Publication of WO2006036715A2 publication Critical patent/WO2006036715A2/en
Publication of WO2006036715A3 publication Critical patent/WO2006036715A3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007Methods or devices for eye surgery
    • A61F9/00781Apparatus for modifying intraocular pressure, e.g. for glaucoma treatment
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/10Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
    • A61B3/16Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for measuring intraocular pressure, e.g. tonometers

Abstract

The invention discloses a trabecular stent and methods for treating glaucoma. The stent may incorporate an intraocular pressure sensor comprising a compressible element that is implanted inside an anterior chamber of an eye, wherein at least one external dimension of the element correlates with intraocular pressure. In some embodiments, the sensor may be coupled to the stent. Also disclosed are methods of delivery of the stent and the sensor to the eye.
PCT/US2005/033900 2004-09-24 2005-09-22 Implant and pressure sensor for glaucoma treatment WO2006036715A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CA002581334A CA2581334A1 (en) 2004-09-24 2005-09-22 Implant with intraocular pressure sensor for glaucoma treatment
AU2005289837A AU2005289837A1 (en) 2004-09-24 2005-09-22 Implant and pressure sensor for glaucoma treatment

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/950,175 2004-09-24
US10/950,175 US7678065B2 (en) 2001-05-02 2004-09-24 Implant with intraocular pressure sensor for glaucoma treatment

Publications (2)

Publication Number Publication Date
WO2006036715A2 WO2006036715A2 (en) 2006-04-06
WO2006036715A3 true WO2006036715A3 (en) 2007-06-07

Family

ID=36119418

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/033900 WO2006036715A2 (en) 2004-09-24 2005-09-22 Implant and pressure sensor for glaucoma treatment

Country Status (4)

Country Link
US (3) US7678065B2 (en)
AU (1) AU2005289837A1 (en)
CA (1) CA2581334A1 (en)
WO (1) WO2006036715A2 (en)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7815592B2 (en) 2003-11-14 2010-10-19 Transcend Medical, Inc. Ocular pressure regulation
US8377122B2 (en) 2009-01-28 2013-02-19 Transcend Medical, Inc. Ocular implant with stiffness qualities, methods of implantation and system
US8444588B2 (en) 2003-05-05 2013-05-21 Transcend Medical, Inc. Internal shunt and method for treating glaucoma
US8617139B2 (en) 2008-06-25 2013-12-31 Transcend Medical, Inc. Ocular implant with shape change capabilities
US8672870B2 (en) 2007-07-17 2014-03-18 Transcend Medical, Inc. Ocular implant with hydrogel expansion capabilities
US8721656B2 (en) 2006-01-17 2014-05-13 Transcend Medical, Inc. Glaucoma treatment device

Families Citing this family (108)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8313454B2 (en) 1997-11-20 2012-11-20 Optonol Ltd. Fluid drainage device, delivery device, and associated methods of use and manufacture
WO2000064389A1 (en) 1999-04-26 2000-11-02 Lynch Mary G Trabeculotomy device and method for treating glaucoma
US20030212383A1 (en) * 2001-01-05 2003-11-13 Dana Cote System and methods for reducing intraocular pressure
US20050119737A1 (en) * 2000-01-12 2005-06-02 Bene Eric A. Ocular implant and methods for making and using same
US6638239B1 (en) 2000-04-14 2003-10-28 Glaukos Corporation Apparatus and method for treating glaucoma
US7867186B2 (en) 2002-04-08 2011-01-11 Glaukos Corporation Devices and methods for treatment of ocular disorders
US7708711B2 (en) 2000-04-14 2010-05-04 Glaukos Corporation Ocular implant with therapeutic agents and methods thereof
US9603741B2 (en) 2000-05-19 2017-03-28 Michael S. Berlin Delivery system and method of use for the eye
US7488303B1 (en) * 2002-09-21 2009-02-10 Glaukos Corporation Ocular implant with anchor and multiple openings
JP4264704B2 (en) * 2001-04-07 2009-05-20 グローコス コーポレーション Glaucoma stent and glaucoma treatment method
US7431710B2 (en) 2002-04-08 2008-10-07 Glaukos Corporation Ocular implants with anchors and methods thereof
US7331984B2 (en) 2001-08-28 2008-02-19 Glaukos Corporation Glaucoma stent for treating glaucoma and methods of use
US7951155B2 (en) 2002-03-15 2011-05-31 Glaukos Corporation Combined treatment for cataract and glaucoma treatment
US9301875B2 (en) 2002-04-08 2016-04-05 Glaukos Corporation Ocular disorder treatment implants with multiple opening
US20040254438A1 (en) 2003-01-09 2004-12-16 The Regents Of The University Of California Implantable devices and methods for measuring intraocular, subconjunctival or subdermal pressure and/or analyte concentration
US7226540B2 (en) * 2004-02-24 2007-06-05 Becton, Dickinson And Company MEMS filter module
US20060173399A1 (en) * 2005-02-01 2006-08-03 Rodgers M S MEMS flow module with pivoting-type baffle
US20060036207A1 (en) * 2004-02-24 2006-02-16 Koonmen James P System and method for treating glaucoma
US7384550B2 (en) * 2004-02-24 2008-06-10 Becton, Dickinson And Company Glaucoma implant having MEMS filter module
US20060219627A1 (en) * 2005-03-31 2006-10-05 Rodgers M S MEMS filter module with concentric filtering walls
US20060206049A1 (en) * 2005-03-14 2006-09-14 Rodgers M S MEMS flow module with piston-type pressure regulating structure
US7544176B2 (en) * 2005-06-21 2009-06-09 Becton, Dickinson And Company Glaucoma implant having MEMS flow module with flexing diaphragm for pressure regulation
US7364564B2 (en) * 2004-03-02 2008-04-29 Becton, Dickinson And Company Implant having MEMS flow module with movable, flow-controlling baffle
US20060247664A1 (en) * 2005-03-08 2006-11-02 California Institute Of Technology Micromachined tissue anchors for securing implants without sutures
US20110077579A1 (en) * 2005-03-24 2011-03-31 Harrison William V Cochlear implant with localized fluid transport
WO2006133400A2 (en) * 2005-06-08 2006-12-14 California Institute Of Technology Intravascular diagnostic and therapeutic sampling device
EP1978892B1 (en) 2006-01-17 2017-11-15 Novartis Ag Drug delivery treatment device
JP2009534129A (en) * 2006-04-18 2009-09-24 カスケード オフタルミクス Intraocular pressure attenuator
EP2015671B1 (en) * 2006-04-26 2012-09-05 Eastern Virginia Medical School Systems for monitoring and controlling internal pressure of an eye or body part
US8267905B2 (en) 2006-05-01 2012-09-18 Neurosystec Corporation Apparatus and method for delivery of therapeutic and other types of agents
US7803148B2 (en) 2006-06-09 2010-09-28 Neurosystec Corporation Flow-induced delivery from a drug mass
WO2008011125A2 (en) * 2006-07-20 2008-01-24 Neurosystec Corporation Devices, systems and methods for ophthalmic drug delivery
EP2786701B1 (en) * 2006-08-29 2015-12-23 California Institute of Technology Microfabricated implantable wireless pressure sensor for use in biomedical applications and pressure measurement and sensor implantation methods
US20080065002A1 (en) * 2006-09-07 2008-03-13 Neurosystec Corporation Catheter for Localized Drug Delivery and/or Electrical Stimulation
US8506515B2 (en) * 2006-11-10 2013-08-13 Glaukos Corporation Uveoscleral shunt and methods for implanting same
ES2284416B1 (en) * 2007-05-21 2009-02-16 Ahmed Galal Ahmed "DEVICE FOR CONTROL OF INTRAOCULAR PRESSURE".
US20170360609A9 (en) 2007-09-24 2017-12-21 Ivantis, Inc. Methods and devices for increasing aqueous humor outflow
US20090082862A1 (en) 2007-09-24 2009-03-26 Schieber Andrew T Ocular Implant Architectures
US7740604B2 (en) * 2007-09-24 2010-06-22 Ivantis, Inc. Ocular implants for placement in schlemm's canal
US8734377B2 (en) 2007-09-24 2014-05-27 Ivantis, Inc. Ocular implants with asymmetric flexibility
US9510844B2 (en) 2007-11-13 2016-12-06 Mgd Innovations, Llc Gland or duct diagnostic and treatment methods and related apparatus
WO2009064834A2 (en) * 2007-11-13 2009-05-22 Maskin Steven L Meibomian gland intraductal diagnostic and treatment methods and related apparatus
US8808222B2 (en) 2007-11-20 2014-08-19 Ivantis, Inc. Methods and apparatus for delivering ocular implants into the eye
US8512404B2 (en) 2007-11-20 2013-08-20 Ivantis, Inc. Ocular implant delivery system and method
FR2924913B1 (en) * 2007-12-18 2010-02-05 Alain Telandro SYSTEM FOR MEASURING OCULAR PRESSURE
US8109896B2 (en) 2008-02-11 2012-02-07 Optonol Ltd. Devices and methods for opening fluid passageways
EP2259833A1 (en) 2008-03-05 2010-12-15 Ivantis, INC. Methods and apparatus for treating glaucoma
WO2009129450A2 (en) * 2008-04-17 2009-10-22 Yale University Method for implanting intraocular pressure sensor
US8926524B2 (en) * 2008-06-02 2015-01-06 California Institute Of Technology System, apparatus and method for biomedical wireless pressure sensing
ES2330405B1 (en) * 2008-06-06 2010-09-21 Consejo Superior De Investigaciones Cientificas (Csic) (45%) SENSOR CONTACT LENS, SYSTEM FOR NON-INVASIVE MONITORING OF INTRAOCULAR PRESSURE AND METHOD TO PUT YOUR MEASUREMENT.
WO2010065970A1 (en) * 2008-12-05 2010-06-10 Ivantis, Inc. Methods and apparatus for delivering ocular implants into the eye
CA2979355C (en) * 2009-05-18 2023-02-21 Dose Medical Corporation Drug eluting ocular implant
US10206813B2 (en) 2009-05-18 2019-02-19 Dose Medical Corporation Implants with controlled drug delivery features and methods of using same
CA2766192C (en) 2009-07-09 2017-10-24 Ivantis, Inc. Ocular implants for residing partially in schlemm's canal
WO2011006078A1 (en) 2009-07-09 2011-01-13 Ivantis, Inc. Single operator device for delivering an ocular implant
CN102711593A (en) 2009-09-18 2012-10-03 奥尔托梅姆斯有限公司 Implantable mems intraocular pressure sensor devices and methods for glaucoma monitoring
CA2778452A1 (en) 2009-10-23 2011-04-28 Ivantis, Inc. Ocular implant system and method
US8529492B2 (en) 2009-12-23 2013-09-10 Trascend Medical, Inc. Drug delivery devices and methods
WO2011082314A2 (en) 2009-12-30 2011-07-07 Brockman Holdings Llc System, device, and method for determination of intraocular pressure
US8545430B2 (en) 2010-06-09 2013-10-01 Transcend Medical, Inc. Expandable ocular devices
WO2011163505A1 (en) 2010-06-23 2011-12-29 Ivantis, Inc. Ocular implants deployed in schlemm's canal of the eye
US20120238857A1 (en) * 2010-09-16 2012-09-20 Orthomems, Inc. Expandable implantable pressure sensor for intraocular surgery
US9370444B2 (en) * 2010-10-12 2016-06-21 Emmett T. Cunningham, JR. Subconjunctival conformer device and uses thereof
US9668915B2 (en) 2010-11-24 2017-06-06 Dose Medical Corporation Drug eluting ocular implant
EP2517619B1 (en) 2011-04-27 2013-05-22 Istar Medical Improvements in or relating to glaucoma management and treatment
US10245178B1 (en) 2011-06-07 2019-04-02 Glaukos Corporation Anterior chamber drug-eluting ocular implant
US8657776B2 (en) 2011-06-14 2014-02-25 Ivantis, Inc. Ocular implants for delivery into the eye
ES2666857T3 (en) 2011-07-18 2018-05-08 Mor-Research Applications Ltd. A device to adjust intraocular pressure
EP4193907A1 (en) 2011-09-13 2023-06-14 Glaukos Corporation Intraocular physiological sensor
US8765210B2 (en) 2011-12-08 2014-07-01 Aquesys, Inc. Systems and methods for making gelatin shunts
US8663150B2 (en) 2011-12-19 2014-03-04 Ivantis, Inc. Delivering ocular implants into the eye
US9554940B2 (en) 2012-03-26 2017-01-31 Glaukos Corporation System and method for delivering multiple ocular implants
US9358156B2 (en) 2012-04-18 2016-06-07 Invantis, Inc. Ocular implants for delivery into an anterior chamber of the eye
US10085633B2 (en) 2012-04-19 2018-10-02 Novartis Ag Direct visualization system for glaucoma treatment
US9241832B2 (en) 2012-04-24 2016-01-26 Transcend Medical, Inc. Delivery system for ocular implant
WO2014043698A2 (en) 2012-09-17 2014-03-20 Transcend Medical, Inc. Expanding ocular implant devices and methods
US9782293B2 (en) 2012-09-28 2017-10-10 Doci Innovations GmbH Implant for treating glaucoma
WO2014078288A1 (en) 2012-11-14 2014-05-22 Transcend Medical, Inc. Flow promoting ocular implant
DE102012221350A1 (en) 2012-11-22 2014-05-22 Universität Rostock Eye implant of eye implant arrangement for treating and monitoring glaucoma disease in eye, has pressure sensors that are provided in casing to detect intraocular pressure at eye, such that supply or disconnection of pump is effected
WO2014085450A1 (en) 2012-11-28 2014-06-05 Ivantis, Inc. Apparatus for delivering ocular implants into an anterior chamber of the eye
US10159600B2 (en) 2013-02-19 2018-12-25 Aquesys, Inc. Adjustable intraocular flow regulation
US9125723B2 (en) 2013-02-19 2015-09-08 Aquesys, Inc. Adjustable glaucoma implant
US9730638B2 (en) 2013-03-13 2017-08-15 Glaukos Corporation Intraocular physiological sensor
US10517759B2 (en) 2013-03-15 2019-12-31 Glaukos Corporation Glaucoma stent and methods thereof for glaucoma treatment
US9592151B2 (en) 2013-03-15 2017-03-14 Glaukos Corporation Systems and methods for delivering an ocular implant to the suprachoroidal space within an eye
US9987163B2 (en) 2013-04-16 2018-06-05 Novartis Ag Device for dispensing intraocular substances
US8967810B1 (en) * 2013-04-30 2015-03-03 Thomas C. Prager Methodology to identify the scleral spur
AU2014348536B2 (en) 2013-11-14 2017-01-12 Aquesys, Inc. Intraocular shunt inserter
WO2015184173A1 (en) 2014-05-29 2015-12-03 Dose Medical Corporation Implants with controlled drug delivery features and methods of using same
CN106714665A (en) 2014-07-01 2017-05-24 注射感知股份有限公司 Methods and devices for implantation of intraocular pressure sensors
CN106714664A (en) 2014-07-01 2017-05-24 注射感知股份有限公司 Hermetically sealed implant sensors with vertical stacking architecture
US10709547B2 (en) 2014-07-14 2020-07-14 Ivantis, Inc. Ocular implant delivery system and method
EP3698703A1 (en) 2015-03-20 2020-08-26 Glaukos Corporation Gonioscopic devices
US10842916B2 (en) 2015-06-24 2020-11-24 Healionics Corporation Injectable porous device for treatment of dry and wet age-related macular degeneration or diabetic retinopathy
AU2016307951B2 (en) * 2015-08-14 2021-04-01 Alcon Inc. Ocular implant with pressure sensor and delivery system
US11925578B2 (en) 2015-09-02 2024-03-12 Glaukos Corporation Drug delivery implants with bi-directional delivery capacity
US11564833B2 (en) 2015-09-25 2023-01-31 Glaukos Corporation Punctal implants with controlled drug delivery features and methods of using same
WO2017106517A1 (en) 2015-12-15 2017-06-22 Ivantis, Inc. Ocular implant and delivery system
EP3442479A1 (en) 2016-04-20 2019-02-20 Harold Alexander Heitzmann Bioresorbable ocular drug delivery device
US10603210B1 (en) 2017-02-02 2020-03-31 Mgd Innovations, Llc Meibomian gland probing with blood product injection
US10674906B2 (en) 2017-02-24 2020-06-09 Glaukos Corporation Gonioscopes
US11116625B2 (en) 2017-09-28 2021-09-14 Glaukos Corporation Apparatus and method for controlling placement of intraocular implants
CA3076833A1 (en) 2017-09-29 2019-04-04 Glaukos Corporation Intraocular physiological sensor
WO2019070385A2 (en) 2017-10-06 2019-04-11 Glaukos Corporation Systems and methods for delivering multiple ocular implants
USD846738S1 (en) 2017-10-27 2019-04-23 Glaukos Corporation Implant delivery apparatus
DE102018203424A1 (en) * 2018-03-07 2019-09-12 Carl Zeiss Meditec Ag Shunt implant
AU2022205382A1 (en) 2021-01-11 2023-06-22 Alcon Inc. Systems and methods for viscoelastic delivery
CN115969312B (en) * 2023-03-22 2023-08-22 中国人民解放军总医院第一医学中心 Intraocular pressure monitoring device connected with glaucoma drainage valve

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6579235B1 (en) * 1999-11-01 2003-06-17 The Johns Hopkins University Method for monitoring intraocular pressure using a passive intraocular pressure sensor and patient worn monitoring recorder

Family Cites Families (276)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2031754A (en) * 1932-11-04 1936-02-25 Ernest J Sweetland Extensible coupling
US3788327A (en) 1971-03-30 1974-01-29 H Donowitz Surgical implant device
US4037604A (en) 1976-01-05 1977-07-26 Newkirk John B Artifical biological drainage device
US4168697A (en) 1977-01-17 1979-09-25 Cantekin Erdem I Middle ear ventilating tube and method
US4113088A (en) 1977-06-06 1978-09-12 Binkhorst Richard D Sterile package
US4175563A (en) 1977-10-05 1979-11-27 Arenberg Irving K Biological drainage shunt
US4402681A (en) 1980-08-23 1983-09-06 Haas Joseph S Artificial implant valve for the regulation of intraocular pressure
US4366582A (en) * 1980-12-01 1983-01-04 Faulkner Gerald D Posterior chamber intraocular lens
NO147900C (en) 1981-03-12 1983-07-06 Finn Skjaerpe MICROSURGICAL INSTRUMENT.
US4428746A (en) 1981-07-29 1984-01-31 Antonio Mendez Glaucoma treatment device
US4468216A (en) 1982-05-20 1984-08-28 Rudolph Muto Irrigation suction catheter
US4554918A (en) 1982-07-28 1985-11-26 White Thomas C Ocular pressure relief device
JPS5985153A (en) * 1982-11-08 1984-05-17 Hitachi Ltd Redundancy controller
US4521210A (en) 1982-12-27 1985-06-04 Wong Vernon G Eye implant for relieving glaucoma, and device and method for use therewith
US4560383A (en) 1983-10-27 1985-12-24 Leiske Larry G Anterior chamber intraocular lens
US4634418A (en) 1984-04-06 1987-01-06 Binder Perry S Hydrogel seton
US4787885A (en) 1984-04-06 1988-11-29 Binder Perry S Hydrogel seton
US4604087A (en) 1985-02-26 1986-08-05 Joseph Neil H Aqueous humor drainage device
US4820626A (en) 1985-06-06 1989-04-11 Thomas Jefferson University Method of treating a synthetic or naturally occuring surface with microvascular endothelial cells, and the treated surface itself
US4632842A (en) 1985-06-20 1986-12-30 Atrium Medical Corporation Glow discharge process for producing implantable devices
US4718907A (en) 1985-06-20 1988-01-12 Atrium Medical Corporation Vascular prosthesis having fluorinated coating with varying F/C ratio
US4883864A (en) 1985-09-06 1989-11-28 Minnesota Mining And Manufacturing Company Modified collagen compound and method of preparation
US4733665C2 (en) 1985-11-07 2002-01-29 Expandable Grafts Partnership Expandable intraluminal graft and method and apparatus for implanting an expandable intraluminal graft
NZ215409A (en) 1986-03-07 1989-02-24 Anthony Christopher Be Molteno Implant for drainage of aqueous humour in glaucoma
CH670760A5 (en) 1986-06-02 1989-07-14 Sulzer Ag
US4722724A (en) 1986-06-23 1988-02-02 Stanley Schocket Anterior chamber tube shunt to an encircling band, and related surgical procedure
US4863457A (en) 1986-11-24 1989-09-05 Lee David A Drug delivery device
US4846793A (en) 1987-03-18 1989-07-11 Endocon, Inc. Injector for implanting multiple pellet medicaments
US4846172A (en) 1987-05-26 1989-07-11 Berlin Michael S Laser-delivery eye-treatment method
US4900300A (en) 1987-07-06 1990-02-13 Lee David A Surgical instrument
US4886488A (en) 1987-08-06 1989-12-12 White Thomas C Glaucoma drainage the lacrimal system and method
CA1295907C (en) 1987-08-06 1992-02-18 Thomas C. White Glaucoma drainage in the lacrimal system
US4870953A (en) 1987-11-13 1989-10-03 Donmicheal T Anthony Intravascular ultrasonic catheter/probe and method for treating intravascular blockage
US4853224A (en) 1987-12-22 1989-08-01 Visionex Biodegradable ocular implants
US4997652A (en) * 1987-12-22 1991-03-05 Visionex Biodegradable ocular implants
US4936825A (en) 1988-04-11 1990-06-26 Ungerleider Bruce A Method for reducing intraocular pressure caused by glaucoma
CA1334168C (en) * 1988-04-26 1995-01-31 Louis M. De Santis Antiglaucoma compositions containing combinations of .alpha.-2 agonists and .beta. blockers
US5005577A (en) 1988-08-23 1991-04-09 Frenkel Ronald E P Intraocular lens pressure monitoring device
US5785674A (en) 1988-10-07 1998-07-28 Mateen; Ahmed Abdul Device and method for treating glaucoma
US5681275A (en) 1988-10-07 1997-10-28 Ahmed; Abdul Mateen Ophthalmological device with adaptable multiple distribution plates
US5098443A (en) * 1989-03-23 1992-03-24 University Of Miami Method of implanting intraocular and intraorbital implantable devices for the controlled release of pharmacological agents
FR2651668B1 (en) 1989-09-12 1991-12-27 Leon Claude MICROSCOPE-ENDOSCOPE ASSEMBLY USEFUL IN PARTICULAR IN SURGERY.
US4946436A (en) 1989-11-17 1990-08-07 Smith Stewart G Pressure-relieving device and process for implanting
USRE35390E (en) 1989-11-17 1996-12-03 Smith; Stewart G. Pressure relieving device and process for implanting
US5164188A (en) 1989-11-22 1992-11-17 Visionex, Inc. Biodegradable ocular implants
US5092837A (en) 1989-12-20 1992-03-03 Robert Ritch Method for the treatment of glaucoma
US4968296A (en) 1989-12-20 1990-11-06 Robert Ritch Transscleral drainage implant device for the treatment of glaucoma
US5073163A (en) 1990-01-29 1991-12-17 Lippman Myron E Apparatus for treating glaucoma
US5180362A (en) 1990-04-03 1993-01-19 Worst J G F Gonio seton
US5129895A (en) 1990-05-16 1992-07-14 Sunrise Technologies, Inc. Laser sclerostomy procedure
US5041081A (en) 1990-05-18 1991-08-20 Odrich Ronald B Ocular implant for controlling glaucoma
US5127901A (en) 1990-05-18 1992-07-07 Odrich Ronald B Implant with subconjunctival arch
US5397300A (en) 1990-05-31 1995-03-14 Iovision, Inc. Glaucoma implant
US5476445A (en) 1990-05-31 1995-12-19 Iovision, Inc. Glaucoma implant with a temporary flow restricting seal
US5178604A (en) 1990-05-31 1993-01-12 Iovision, Inc. Glaucoma implant
US5725529A (en) * 1990-09-25 1998-03-10 Innovasive Devices, Inc. Bone fastener
US5454796A (en) 1991-04-09 1995-10-03 Hood Laboratories Device and method for controlling intraocular fluid pressure
US5312394A (en) 1991-04-29 1994-05-17 Hugh Beckman Apparatus and method for surgically performing a filtering operation on an eye for glaucoma
US5246451A (en) 1991-04-30 1993-09-21 Medtronic, Inc. Vascular prosthesis and method
US6007511A (en) 1991-05-08 1999-12-28 Prywes; Arnold S. Shunt valve and therapeutic delivery system for treatment of glaucoma and methods and apparatus for its installation
US5300020A (en) 1991-05-31 1994-04-05 Medflex Corporation Surgically implantable device for glaucoma relief
US5171213A (en) 1991-08-14 1992-12-15 Price Jr Francis W Technique for fistulization of the eye and an eye filtration prosthesis useful therefor
SG81873A1 (en) 1991-08-16 2001-07-24 Miles A Galin Medicament coated refractive anterior chamber ocular implant
US5500013A (en) 1991-10-04 1996-03-19 Scimed Life Systems, Inc. Biodegradable drug delivery vascular stent
GB2260585A (en) 1991-10-09 1993-04-21 Avdel Systems Ltd Self-plugging blind rivet
US5360399A (en) 1992-01-10 1994-11-01 Robert Stegmann Method and apparatus for maintaining the normal intraocular pressure
US5207685A (en) * 1992-02-11 1993-05-04 Cinberg James Z Tympanic ventilation tube and related technique
US5334137A (en) 1992-02-21 1994-08-02 Eagle Vision, Inc. Lacrimal fluid control device
US5346464A (en) 1992-03-10 1994-09-13 Camras Carl B Method and apparatus for reducing intraocular pressure
US5370641A (en) 1992-05-22 1994-12-06 O'donnell, Jr.; Francis E. Laser trabeculodissection
US5663205A (en) 1992-05-22 1997-09-02 Senju Pharmaceutical Co. Ltd. Pharmaceutical composition for use in glaucoma treatment
US5629008A (en) 1992-06-02 1997-05-13 C.R. Bard, Inc. Method and device for long-term delivery of drugs
DE4219299C2 (en) 1992-06-12 1994-03-24 Leica Mikroskopie & Syst microscope
US5767079A (en) 1992-07-08 1998-06-16 Celtrix Pharmaceuticals, Inc. Method of treating ophthalmic disorders using TGF -β
US5290295A (en) 1992-07-15 1994-03-01 Querals & Fine, Inc. Insertion tool for an intraluminal graft procedure
US6197056B1 (en) 1992-07-15 2001-03-06 Ras Holding Corp. Segmented scleral band for treatment of presbyopia and other eye disorders
US5318513A (en) 1992-09-24 1994-06-07 Leib Martin L Canalicular balloon fixation stent
US5370607A (en) 1992-10-28 1994-12-06 Annuit Coeptis, Inc. Glaucoma implant device and method for implanting same
WO1994013234A1 (en) 1992-12-17 1994-06-23 Michael Andrew Coote Implant device and method for treatment of glaucoma
US5338291A (en) 1993-02-03 1994-08-16 Pudenz-Schulte Medical Research Corporation Glaucoma shunt and method for draining aqueous humor
AU685063B2 (en) 1993-03-16 1998-01-15 Photogenesis, Incorporated Method for preparation and transplantation of volute grafts and surgical instrument therefor
US5342370A (en) 1993-03-19 1994-08-30 University Of Miami Method and apparatus for implanting an artifical meshwork in glaucoma surgery
IL105828A (en) 1993-05-28 1999-06-20 Medinol Ltd Medical stent
US5731294A (en) 1993-07-27 1998-03-24 Hybridon, Inc. Inhibition of neovasularization using VEGF-specific oligonucleotides
US6184250B1 (en) * 1993-08-03 2001-02-06 Alcon Laboratories, Inc. Use of cloprostenol and fluprostenol analogues to treat glaucoma and ocular hypertension
US5735892A (en) 1993-08-18 1998-04-07 W. L. Gore & Associates, Inc. Intraluminal stent graft
FR2710269A1 (en) 1993-09-22 1995-03-31 Voir Vivre Implantable device for the treatment of edemas.
FI934513A (en) 1993-10-13 1995-04-14 Leiras Oy Anordning Foer injection with implant
US5639278A (en) 1993-10-21 1997-06-17 Corvita Corporation Expandable supportive bifurcated endoluminal grafts
US5443505A (en) 1993-11-15 1995-08-22 Oculex Pharmaceuticals, Inc. Biocompatible ocular implants
US5743868A (en) 1994-02-14 1998-04-28 Brown; Reay H. Corneal pressure-regulating implant device
US5516522A (en) 1994-03-14 1996-05-14 Board Of Supervisors Of Louisiana State University Biodegradable porous device for long-term drug delivery with constant rate release and method of making the same
US6165210A (en) 1994-04-01 2000-12-26 Gore Enterprise Holdings, Inc. Self-expandable helical intravascular stent and stent-graft
EP0754046A1 (en) * 1994-04-04 1997-01-22 FREEMAN, William R. Use of phosphonylmethoxyalkyl nucleosides for the treatment of raised intraocular pressure
US5716394A (en) 1994-04-29 1998-02-10 W. L. Gore & Associates, Inc. Blood contact surfaces using extracellular matrix synthesized in vitro
IL109499A (en) 1994-05-02 1998-01-04 Univ Ramot Implant device for draining excess intraocular fluid
FR2721499B1 (en) 1994-06-22 1997-01-03 Opsia Trabeculectomy implant.
US6177427B1 (en) * 1994-06-28 2001-01-23 Alcon Laboratories, Inc. Treatment of glaucoma and ocular hypertension
US5520631A (en) 1994-07-22 1996-05-28 Wound Healing Of Oklahoma Method and apparatus for lowering the intraocular pressure of an eye
US5704907A (en) 1994-07-22 1998-01-06 Wound Healing Of Oklahoma Method and apparatus for lowering the intraocular pressure of an eye
US6102045A (en) 1994-07-22 2000-08-15 Premier Laser Systems, Inc. Method and apparatus for lowering the intraocular pressure of an eye
US5599534A (en) * 1994-08-09 1997-02-04 University Of Nebraska Reversible gel-forming composition for sustained delivery of bio-affecting substances, and method of use
US5665114A (en) 1994-08-12 1997-09-09 Meadox Medicals, Inc. Tubular expanded polytetrafluoroethylene implantable prostheses
SE9402816D0 (en) 1994-08-24 1994-08-24 Pharmacia Ab Method and meams for drug administration
DE4433104C1 (en) 1994-09-16 1996-05-02 Fraunhofer Ges Forschung Device for measuring mechanical properties of biological tissue
US5702419A (en) 1994-09-21 1997-12-30 Wake Forest University Expandable, intraluminal stents
US6063396A (en) 1994-10-26 2000-05-16 Houston Biotechnology Incorporated Methods and compositions for the modulation of cell proliferation and wound healing
US6063116A (en) 1994-10-26 2000-05-16 Medarex, Inc. Modulation of cell proliferation and wound healing
US5643321A (en) 1994-11-10 1997-07-01 Innovasive Devices Suture anchor assembly and methods
JP3642812B2 (en) 1994-11-17 2005-04-27 株式会社町田製作所 Medical observation device
US5601094A (en) 1994-11-22 1997-02-11 Reiss; George R. Ophthalmic shunt
US5602143A (en) 1994-12-08 1997-02-11 Allergan Method for reducing intraocular pressure in the mammalian eye by administration of guanylate cyclase inhibitors
US6228873B1 (en) 1994-12-09 2001-05-08 The Regents Of The University Of California Method for enhancing outflow of aqueous humor in treatment of glaucoma
US5725493A (en) 1994-12-12 1998-03-10 Avery; Robert Logan Intravitreal medicine delivery
US5433701A (en) 1994-12-21 1995-07-18 Rubinstein; Mark H. Apparatus for reducing ocular pressure
US5891084A (en) * 1994-12-27 1999-04-06 Lee; Vincent W. Multiple chamber catheter delivery system
US5558630A (en) 1994-12-30 1996-09-24 Fisher; Bret L. Intrascleral implant and method for the regulation of intraocular pressure
GB2296663A (en) 1995-01-03 1996-07-10 Ahmed Salih Mahmud Drainage device for alleviating excess ophthalmic fluid pressure
WO1996020742A1 (en) 1995-01-06 1996-07-11 Wong Vernon G Improve eye implant for relief of glaucoma
WO1996024346A1 (en) 1995-02-10 1996-08-15 The University Of Toronto Innovations Foundation Deprenyl compounds for treatment of glaucoma
US6059772A (en) 1995-03-10 2000-05-09 Candela Corporation Apparatus and method for treating glaucoma using a gonioscopic laser trabecular ablation procedure
BE1009278A3 (en) 1995-04-12 1997-01-07 Corvita Europ Guardian self-expandable medical device introduced in cavite body, and medical device with a stake as.
US5626558A (en) 1995-05-05 1997-05-06 Suson; John Adjustable flow rate glaucoma shunt and method of using same
IL113723A (en) 1995-05-14 2002-11-10 Optonol Ltd Intraocular implant
US5968058A (en) 1996-03-27 1999-10-19 Optonol Ltd. Device for and method of implanting an intraocular implant
DE69633074T2 (en) 1995-05-14 2004-12-30 Optonol Ltd. INTRAOCULAR IMPLANT, INSERTION DEVICE AND IMPLANTATION PROCEDURE
EP0773754B1 (en) 1995-05-25 2004-09-01 Medtronic, Inc. Stent assembly
US5723005A (en) 1995-06-07 1998-03-03 Herrick Family Limited Partnership Punctum plug having a collapsible flared section and method
CA2223479A1 (en) 1995-06-08 1996-12-27 Bard Galway Limited Endovascular stent
US6194415B1 (en) * 1995-06-28 2001-02-27 Allergan Sales, Inc. Method of using (2-imidazolin-2-ylamino) quinoxoalines in treating neural injury
US5934285A (en) 1995-07-27 1999-08-10 Michiel S. Kritzinger Method for reducing irregular astigmatism and debris/epithelium in the interface during lamellar corneal flap/cap surgery
US5766243A (en) 1995-08-21 1998-06-16 Oasis Medical, Inc. Abrasive polished canalicular implant
US5547993A (en) 1995-10-24 1996-08-20 Mitsubishi Chemical Corporation Therapeutic agent for glaucoma
US5836939A (en) 1995-10-25 1998-11-17 Plc Medical Systems, Inc. Surgical laser handpiece
US6045557A (en) 1995-11-10 2000-04-04 Baxter International Inc. Delivery catheter and method for positioning an intraluminal graft
US5651783A (en) 1995-12-20 1997-07-29 Reynard; Michael Fiber optic sleeve for surgical instruments
AU1201297A (en) 1995-12-21 1997-07-17 Pharmacia & Upjohn Ab Ophthalmic treatment
US5798380A (en) 1996-02-21 1998-08-25 Wisconsin Alumni Research Foundation Cytoskeletal active agents for glaucoma therapy
US6299895B1 (en) 1997-03-24 2001-10-09 Neurotech S.A. Device and method for treating ophthalmic diseases
US5807302A (en) 1996-04-01 1998-09-15 Wandel; Thaddeus Treatment of glaucoma
US6629981B2 (en) 2000-07-06 2003-10-07 Endocare, Inc. Stent delivery system
US5830179A (en) 1996-04-09 1998-11-03 Endocare, Inc. Urological stent therapy system and method
US5865831A (en) 1996-04-17 1999-02-02 Premier Laser Systems, Inc. Laser surgical procedures for treatment of glaucoma
US5932299A (en) 1996-04-23 1999-08-03 Katoot; Mohammad W. Method for modifying the surface of an object
US6530896B1 (en) * 1996-05-13 2003-03-11 James B. Elliott Apparatus and method for introducing an implant
US5670161A (en) 1996-05-28 1997-09-23 Healy; Kevin E. Biodegradable stent
US5681323A (en) 1996-07-15 1997-10-28 Arick; Daniel S. Emergency cricothyrotomy tube insertion
US5830139A (en) 1996-09-04 1998-11-03 Abreu; Marcio M. Tonometer system for measuring intraocular pressure by applanation and/or indentation
US6544193B2 (en) 1996-09-04 2003-04-08 Marcio Marc Abreu Noninvasive measurement of chemical substances
US6120460A (en) 1996-09-04 2000-09-19 Abreu; Marcio Marc Method and apparatus for signal acquisition, processing and transmission for evaluation of bodily functions
US5886822A (en) 1996-10-08 1999-03-23 The Microoptical Corporation Image combining system for eyeglasses and face masks
US6007510A (en) 1996-10-25 1999-12-28 Anamed, Inc. Implantable devices and methods for controlling the flow of fluids within the body
US5925342A (en) 1996-11-13 1999-07-20 Allergan Method for reducing intraocular pressure in the mammalian eye by administration of potassium channel blockers
AUPO394496A0 (en) 1996-11-29 1997-01-02 Lions Eye Institute Biological microfistula tube and implantation method and apparatus
US6261256B1 (en) 1996-12-20 2001-07-17 Abdul Mateen Ahmed Pocket medical valve & method
US5713844A (en) 1997-01-10 1998-02-03 Peyman; Gholam A. Device and method for regulating intraocular pressure
GB9700390D0 (en) * 1997-01-10 1997-02-26 Biocompatibles Ltd Device for use in the eye
US6780165B2 (en) 1997-01-22 2004-08-24 Advanced Medical Optics Micro-burst ultrasonic power delivery
DE19705815C2 (en) 1997-02-15 1999-02-11 Heidelberg Engineering Optisch Medical device for microsurgery on the eye
FR2759577B1 (en) 1997-02-17 1999-08-06 Corneal Ind DEEP SCLERECTOMY IMPLANT
US6071286A (en) 1997-02-19 2000-06-06 Mawad; Michel E. Combination angioplasty balloon/stent deployment device
US5893837A (en) 1997-02-28 1999-04-13 Staar Surgical Company, Inc. Glaucoma drain implanting device and method
US6059812A (en) 1997-03-21 2000-05-09 Schneider (Usa) Inc. Self-expanding medical device for centering radioactive treatment sources in body vessels
JP3827429B2 (en) 1997-04-03 2006-09-27 オリンパス株式会社 Surgical microscope
US5882327A (en) 1997-04-17 1999-03-16 Jacob; Jean T. Long-term glaucoma drainage implant
US6033418A (en) * 1997-04-25 2000-03-07 New Jersey Institute Of Technology Method and device for corneal shaping and refractive correction
US6050970A (en) 1997-05-08 2000-04-18 Pharmacia & Upjohn Company Method and apparatus for inserting a glaucoma implant in an anterior and posterior segment of the eye
DE19728069C1 (en) 1997-07-01 1999-02-11 Acritec Gmbh Device for measuring intraocular pressure
US5752928A (en) 1997-07-14 1998-05-19 Rdo Medical, Inc. Glaucoma pressure regulator
US5980928A (en) 1997-07-29 1999-11-09 Terry; Paul B. Implant for preventing conjunctivitis in cattle
US5830171A (en) 1997-08-12 1998-11-03 Odyssey Medical, Inc. Punctal occluder
EP0898947A3 (en) 1997-08-15 1999-09-08 GRIESHABER & CO. AG SCHAFFHAUSEN Method and apparatus to improve the outflow of the aqueous humor of an eye
US6004302A (en) 1997-08-28 1999-12-21 Brierley; Lawrence A. Cannula
US6274138B1 (en) 1997-09-03 2001-08-14 Incyte Genomics, Inc. Human mitochondrial malate dehydrogenase
US6159458A (en) 1997-11-04 2000-12-12 Insite Vision Sustained release ophthalmic compositions containing water soluble medicaments
US8313454B2 (en) 1997-11-20 2012-11-20 Optonol Ltd. Fluid drainage device, delivery device, and associated methods of use and manufacture
US6203513B1 (en) 1997-11-20 2001-03-20 Optonol Ltd. Flow regulating implant, method of manufacture, and delivery device
US6165209A (en) 1997-12-15 2000-12-26 Prolifix Medical, Inc. Vascular stent for reduction of restenosis
US6050999A (en) * 1997-12-18 2000-04-18 Keravision, Inc. Corneal implant introducer and method of use
US6168575B1 (en) 1998-01-29 2001-01-02 David Pyam Soltanpour Method and apparatus for controlling intraocular pressure
US6268398B1 (en) 1998-04-24 2001-07-31 Mitokor Compounds and methods for treating mitochondria-associated diseases
US6231853B1 (en) 1998-06-01 2001-05-15 Incyte Pharmaceuticals, Inc. Human glutathione peroxidase-6
US6077299A (en) 1998-06-22 2000-06-20 Eyetronic, Llc Non-invasively adjustable valve implant for the drainage of aqueous humor in glaucoma
US6378526B1 (en) * 1998-08-03 2002-04-30 Insite Vision, Incorporated Methods of ophthalmic administration
DE19840047B4 (en) 1998-09-02 2004-07-08 Neuhann, Thomas, Prof.Dr.med. Device for the targeted improvement and / or permanent guarantee of the permeability for eye chamber water through the trabecular mechanism in the Schlemm's Canal
KR100300527B1 (en) 1998-09-03 2001-10-27 윤덕용 Remote pressure monitoring device of sealed type and manufacture method for the same
US6241721B1 (en) 1998-10-09 2001-06-05 Colette Cozean Laser surgical procedures for treatment of glaucoma
US6254612B1 (en) 1998-10-22 2001-07-03 Cordis Neurovascular, Inc. Hydraulic stent deployment system
US6370641B1 (en) * 1999-01-26 2002-04-09 Dell Usa, L.P. Method and apparatus for determining the drive letter assignment of a CD-ROM drive during initial system setup of a computer system
US6348042B1 (en) * 1999-02-02 2002-02-19 W. Lee Warren, Jr. Bioactive shunt
US6193656B1 (en) 1999-02-08 2001-02-27 Robert E. Jeffries Intraocular pressure monitoring/measuring apparatus and method
US6231597B1 (en) 1999-02-16 2001-05-15 Mark E. Deem Apparatus and methods for selectively stenting a portion of a vessel wall
US6217895B1 (en) * 1999-03-22 2001-04-17 Control Delivery Systems Method for treating and/or preventing retinal diseases with sustained release corticosteroids
WO2000064389A1 (en) 1999-04-26 2000-11-02 Lynch Mary G Trabeculotomy device and method for treating glaucoma
US20050119601A9 (en) * 1999-04-26 2005-06-02 Lynch Mary G. Shunt device and method for treating glaucoma
US6342058B1 (en) 1999-05-14 2002-01-29 Valdemar Portney Iris fixated intraocular lens and instrument for attaching same to an iris
US6558342B1 (en) 1999-06-02 2003-05-06 Optonol Ltd. Flow control device, introducer and method of implanting
US6306120B1 (en) 1999-06-07 2001-10-23 Ben Gee Tan Applicator and method for delivery of mitomycin to eye tissues during glaucoma filtering surgery
US6201001B1 (en) * 1999-08-02 2001-03-13 Abbott Laboratories Imidazole antiproliferative agents
US7033603B2 (en) * 1999-08-06 2006-04-25 Board Of Regents The University Of Texas Drug releasing biodegradable fiber for delivery of therapeutics
US6596296B1 (en) 1999-08-06 2003-07-22 Board Of Regents, The University Of Texas System Drug releasing biodegradable fiber implant
US6187016B1 (en) 1999-09-14 2001-02-13 Daniel G. Hedges Stent retrieval device
DE19945879C2 (en) 1999-09-24 2002-01-03 Acritec Gmbh Device for measuring the intraocular pressure with a foldable implant
US6416777B1 (en) 1999-10-21 2002-07-09 Alcon Universal Ltd. Ophthalmic drug delivery device
PT1473003E (en) 1999-10-21 2008-12-26 Alcon Inc Drug delivery device
US6331313B1 (en) 1999-10-22 2001-12-18 Oculex Pharmaceticals, Inc. Controlled-release biocompatible ocular drug delivery implant devices and methods
US6287313B1 (en) 1999-11-23 2001-09-11 Sdgi Holdings, Inc. Screw delivery system and method
DE29920949U1 (en) 1999-11-29 2000-04-27 Bugge Mogens Suction tube for surgical purposes
KR100771149B1 (en) 1999-12-10 2007-10-30 아이싸이언스 인터벤셔날 코포레이션 Treatment of ocular disease
US6939299B1 (en) 1999-12-13 2005-09-06 Kurt Petersen Implantable continuous intraocular pressure sensor
US6450937B1 (en) 1999-12-17 2002-09-17 C. R. Bard, Inc. Needle for implanting brachytherapy seeds
US6726676B2 (en) 2000-01-05 2004-04-27 Grieshaber & Co. Ag Schaffhausen Method of and device for improving the flow of aqueous humor within the eye
CA2397166A1 (en) 2000-01-12 2001-07-19 Becton, Dickinson And Company Systems and methods for reducing intraocular pressure
US20050119737A1 (en) 2000-01-12 2005-06-02 Bene Eric A. Ocular implant and methods for making and using same
US6589203B1 (en) 2000-01-26 2003-07-08 Peter Mitrev Glaucoma drainage device implant
US6375642B1 (en) 2000-02-15 2002-04-23 Grieshaber & Co. Ag Schaffhausen Method of and device for improving a drainage of aqueous humor within the eye
US6471666B1 (en) 2000-02-24 2002-10-29 Steven A. Odrich Injectable glaucoma device
US20030060752A1 (en) 2000-04-14 2003-03-27 Olav Bergheim Glaucoma device and methods thereof
US7708711B2 (en) 2000-04-14 2010-05-04 Glaukos Corporation Ocular implant with therapeutic agents and methods thereof
US20050049578A1 (en) * 2000-04-14 2005-03-03 Hosheng Tu Implantable ocular pump to reduce intraocular pressure
US7867186B2 (en) 2002-04-08 2011-01-11 Glaukos Corporation Devices and methods for treatment of ocular disorders
US20020143284A1 (en) 2001-04-03 2002-10-03 Hosheng Tu Drug-releasing trabecular implant for glaucoma treatment
US20040111050A1 (en) 2000-04-14 2004-06-10 Gregory Smedley Implantable ocular pump to reduce intraocular pressure
US6533768B1 (en) 2000-04-14 2003-03-18 The Regents Of The University Of California Device for glaucoma treatment and methods thereof
US6638239B1 (en) 2000-04-14 2003-10-28 Glaukos Corporation Apparatus and method for treating glaucoma
US6696415B2 (en) * 2000-04-17 2004-02-24 Children's Hospital Research Foundation Treatment of ocular neovascularization and related diseases
DE60131273T2 (en) * 2000-05-19 2008-08-28 Michael S. Beverly Hills Berlin LASER APPLICATION SYSTEM AND METHOD FOR EYE-USE
US6582453B1 (en) 2000-07-14 2003-06-24 Opus Medical, Inc. Method and apparatus for attaching connective tissues to bone using a suture anchoring device
US6749568B2 (en) 2000-08-21 2004-06-15 Cleveland Clinic Foundation Intraocular pressure measurement system including a sensor mounted in a contact lens
US6699211B2 (en) 2000-08-22 2004-03-02 James A. Savage Method and apparatus for treatment of glaucoma
US6428501B1 (en) 2000-09-19 2002-08-06 K2 Limited Partnership U/A/D Surgical instrument sleeve
US6730056B1 (en) 2000-09-21 2004-05-04 Motorola, Inc. Eye implant for treating glaucoma and method for manufacturing same
US6595945B2 (en) 2001-01-09 2003-07-22 J. David Brown Glaucoma treatment device and method
US6824521B2 (en) 2001-01-22 2004-11-30 Integrated Sensing Systems, Inc. Sensing catheter system and method of fabrication
WO2002074052A2 (en) 2001-03-16 2002-09-26 Glaukos Corporation Applicator and methods for placing a trabecular shunt for glaucoma treatment
US7431710B2 (en) * 2002-04-08 2008-10-07 Glaukos Corporation Ocular implants with anchors and methods thereof
US6981958B1 (en) 2001-05-02 2006-01-03 Glaukos Corporation Implant with pressure sensor for glaucoma treatment
US6666841B2 (en) 2001-05-02 2003-12-23 Glaukos Corporation Bifurcatable trabecular shunt for glaucoma treatment
JP4264704B2 (en) 2001-04-07 2009-05-20 グローコス コーポレーション Glaucoma stent and glaucoma treatment method
US7094225B2 (en) 2001-05-03 2006-08-22 Glaukos Corporation Medical device and methods of use of glaucoma treatment
CN1592640A (en) 2001-08-16 2005-03-09 Gmp视觉方案公司 Shunt device and method for treating glaucoma
US7331984B2 (en) 2001-08-28 2008-02-19 Glaukos Corporation Glaucoma stent for treating glaucoma and methods of use
US20030097151A1 (en) 2001-10-25 2003-05-22 Smedley Gregory T. Apparatus and mitochondrial treatment for glaucoma
US7163543B2 (en) 2001-11-08 2007-01-16 Glaukos Corporation Combined treatment for cataract and glaucoma treatment
US20030093084A1 (en) 2001-11-13 2003-05-15 Optonol Ltd. Delivery devices for flow regulating implants
AU2003219932A1 (en) 2002-02-28 2003-09-16 Gmp Vision Solutions, Inc. Device and method for monitoring aqueous flow within the eye
US7186232B1 (en) 2002-03-07 2007-03-06 Glaukoa Corporation Fluid infusion methods for glaucoma treatment
US20030229303A1 (en) 2002-03-22 2003-12-11 Haffner David S. Expandable glaucoma implant and methods of use
US20040024345A1 (en) 2002-04-19 2004-02-05 Morteza Gharib Glaucoma implant with valveless flow bias
US20070123767A1 (en) 2002-05-31 2007-05-31 Valentino Montegrande Intraocular pressure sensor and method of use
US20050159660A1 (en) 2002-05-31 2005-07-21 Valentino Montegrande Intraocular pressure sensor
US20030236483A1 (en) 2002-06-25 2003-12-25 Ren David H Dual drainage ocular shunt for glaucoma
AU2003256657A1 (en) 2002-07-19 2004-02-09 Yale University Uveoscleral drainage device
AU2003268169A1 (en) 2002-08-27 2004-03-19 Michigan State University Implantable microscale pressure sensor system
US7615010B1 (en) 2002-10-03 2009-11-10 Integrated Sensing Systems, Inc. System for monitoring the physiologic parameters of patients with congestive heart failure
US7131945B2 (en) 2002-10-16 2006-11-07 California Institute Of Technology Optically powered and optically data-transmitting wireless intraocular pressure sensor device
USD490152S1 (en) 2003-02-28 2004-05-18 Glaukos Corporation Surgical handpiece
US20040225250A1 (en) 2003-05-05 2004-11-11 Michael Yablonski Internal shunt and method for treating glaucoma
US20060069340A1 (en) * 2003-06-16 2006-03-30 Solx, Inc. Shunt for the treatment of glaucoma
EP1638508B1 (en) 2003-06-16 2014-08-13 Solx, Inc. Shunt for the treatment of glaucoma
US7291125B2 (en) 2003-11-14 2007-11-06 Transcend Medical, Inc. Ocular pressure regulation
AU2004293075A1 (en) * 2003-11-20 2005-06-09 Angiotech International Ag Soft tissue implants and anti-scarring agents
US20100173866A1 (en) 2004-04-29 2010-07-08 Iscience Interventional Corporation Apparatus and method for ocular treatment
US20080058704A1 (en) * 2004-04-29 2008-03-06 Michael Hee Apparatus and Method for Ocular Treatment
CN1976732A (en) * 2004-04-29 2007-06-06 i科学外科公司 Apparatus and method for surgical enhancement of aqueous humor drainage
US7252006B2 (en) 2004-06-07 2007-08-07 California Institute Of Technology Implantable mechanical pressure sensor and method of manufacturing the same
EP1978892B1 (en) 2006-01-17 2017-11-15 Novartis Ag Drug delivery treatment device
ES2762239T3 (en) 2006-01-17 2020-05-22 Alcon Inc Glaucoma treatment device
US20070202186A1 (en) 2006-02-22 2007-08-30 Iscience Interventional Corporation Apparatus and formulations for suprachoroidal drug delivery
JP2009534129A (en) * 2006-04-18 2009-09-24 カスケード オフタルミクス Intraocular pressure attenuator
EP2015671B1 (en) 2006-04-26 2012-09-05 Eastern Virginia Medical School Systems for monitoring and controlling internal pressure of an eye or body part
US20080306429A1 (en) 2007-06-07 2008-12-11 Shields Milton B Uveoscleral drainage device
JP5328788B2 (en) 2007-07-17 2013-10-30 トランセンド・メディカル・インコーポレイテッド Intraocular implant with hydrogel expansion capability
EP2182841A4 (en) * 2007-08-23 2013-04-03 Purdue Research Foundation Intra-occular pressure sensor
US20100152565A1 (en) 2008-07-15 2010-06-17 Thomas Gordon A Non-invasive tonometer
EP2361033A4 (en) 2008-12-22 2012-09-12 Integrated Sensing Systems Inc Wireless dynamic power control of an implantable sensing device and methods therefor

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6579235B1 (en) * 1999-11-01 2003-06-17 The Johns Hopkins University Method for monitoring intraocular pressure using a passive intraocular pressure sensor and patient worn monitoring recorder

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8444588B2 (en) 2003-05-05 2013-05-21 Transcend Medical, Inc. Internal shunt and method for treating glaucoma
US7815592B2 (en) 2003-11-14 2010-10-19 Transcend Medical, Inc. Ocular pressure regulation
US7850638B2 (en) 2003-11-14 2010-12-14 Transcend Medical, Inc. Ocular pressure regulation
US8486000B2 (en) 2003-11-14 2013-07-16 Transcend Medical, Inc. Ocular pressure regulation
US8721656B2 (en) 2006-01-17 2014-05-13 Transcend Medical, Inc. Glaucoma treatment device
US8734378B2 (en) 2006-01-17 2014-05-27 Transcend Medical, Inc. Glaucoma treatment device
US8672870B2 (en) 2007-07-17 2014-03-18 Transcend Medical, Inc. Ocular implant with hydrogel expansion capabilities
US9585789B2 (en) 2007-07-17 2017-03-07 Novartis Ag Ocular implant with hydrogel expansion capabilities
US8617139B2 (en) 2008-06-25 2013-12-31 Transcend Medical, Inc. Ocular implant with shape change capabilities
US8377122B2 (en) 2009-01-28 2013-02-19 Transcend Medical, Inc. Ocular implant with stiffness qualities, methods of implantation and system

Also Published As

Publication number Publication date
US20100106073A1 (en) 2010-04-29
WO2006036715A2 (en) 2006-04-06
US20050119636A1 (en) 2005-06-02
US20120259195A1 (en) 2012-10-11
US7678065B2 (en) 2010-03-16
US8142364B2 (en) 2012-03-27
CA2581334A1 (en) 2006-04-06
AU2005289837A1 (en) 2006-04-06
AU2005289837A2 (en) 2006-04-06

Similar Documents

Publication Publication Date Title
WO2006036715A3 (en) Implant and pressure sensor for glaucoma treatment
WO2010093945A3 (en) Uveoscleral drug delivery implant and methods for implanting the same
WO2010088258A3 (en) Ocular implant with stiffness qualities, methods of implantation and system
WO2008061043A3 (en) Uveoscleral shunt and methods for implanting same
WO2009042596A3 (en) Ocular implants and methods
WO2008131282A3 (en) Biomechanical design of intracorneal inlays
AU2002338483A1 (en) Drainage implant for draining aqueous humour from the anterior aqueous chamber of the eye into schlemm's canal
ATE304823T1 (en) EYE CORNEAL IMPLANT
DE60325615D1 (en) IMPLANTABLE OXULAR PUMP FOR REDUCING EYE REMINDER
WO2006071548A3 (en) Aminopyrazine analogs for treating glaucoma and other rho kinase-mediated diseases
WO2017030917A8 (en) Ocular implant with pressure sensor and delivery system
WO2007076360A8 (en) (indazol-5-yl)-pyrazines and (1,3-dihydro-indol-2-one)- pyrazines for treating rho kinase-mediated diseases and conditions
WO2010059214A3 (en) Biocompatible biodegradable intraocular implant system
AU3920100A (en) Positive power anterior chamber ocular implant
TW200605918A (en) Biodegradable intravitreal tyrosine kinase implants
EP1310222A3 (en) Drug-releasing trabecular implant for glaucoma treatment
CA2284963A1 (en) Deformable intraocular corrective lens
WO2006113564A3 (en) Corneal implant for altering the refractive properties of the eye
DE502007005198D1 (en) CORNEAL IMPLANT
EP2116215A3 (en) Shunt device for treating glaucoma
JP2009535162A5 (en)
WO2005107706A3 (en) Biodegradable intravitreal tyrosine kinase inhibitors implants
BR0110944A (en) Method of preselecting a polymerizable fluid formed within an intraocular lens
WO2008060359A3 (en) Biodegradable ocular implants and methods for treating ocular conditions
WO2006032812A3 (en) Prosthetic assembly for tissue reinforcement in the treatment of inguinal hernias

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BW BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE EG ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KM KP KR KZ LC LK LR LS LT LU LV LY MA MD MG MK MN MW MX MZ NA NG NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SM SY TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): BW GH GM KE LS MW MZ NA SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LT LU LV MC NL PL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
WWE Wipo information: entry into national phase

Ref document number: 2581334

Country of ref document: CA

WWE Wipo information: entry into national phase

Ref document number: 2005289837

Country of ref document: AU

NENP Non-entry into the national phase

Ref country code: DE

ENP Entry into the national phase

Ref document number: 2005289837

Country of ref document: AU

Date of ref document: 20050922

Kind code of ref document: A

WWP Wipo information: published in national office

Ref document number: 2005289837

Country of ref document: AU

122 Ep: pct application non-entry in european phase

Ref document number: 05799956

Country of ref document: EP

Kind code of ref document: A2