WO2006066049A3 - Humanized antibodies that recognize beta amyloid peptide - Google Patents
Humanized antibodies that recognize beta amyloid peptide Download PDFInfo
- Publication number
- WO2006066049A3 WO2006066049A3 PCT/US2005/045515 US2005045515W WO2006066049A3 WO 2006066049 A3 WO2006066049 A3 WO 2006066049A3 US 2005045515 W US2005045515 W US 2005045515W WO 2006066049 A3 WO2006066049 A3 WO 2006066049A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- humanized antibodies
- amyloid peptide
- beta amyloid
- recognize beta
- recognize
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Abstract
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES05854278T ES2396555T3 (en) | 2004-12-15 | 2005-12-15 | Antibodies that recognize beta amyloid peptide |
EP05854278A EP1838854B1 (en) | 2004-12-15 | 2005-12-15 | Antibodies that recognize Beta Amyloid Peptide |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US63668404P | 2004-12-15 | 2004-12-15 | |
US60/636,684 | 2004-12-15 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2006066049A2 WO2006066049A2 (en) | 2006-06-22 |
WO2006066049A3 true WO2006066049A3 (en) | 2006-10-05 |
Family
ID=36588573
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2005/045515 WO2006066049A2 (en) | 2004-12-15 | 2005-12-15 | Humanized antibodies that recognize beta amyloid peptide |
Country Status (8)
Country | Link |
---|---|
US (1) | US7625560B2 (en) |
EP (1) | EP1838854B1 (en) |
AR (1) | AR051528A1 (en) |
ES (1) | ES2396555T3 (en) |
PE (1) | PE20061152A1 (en) |
TW (1) | TW200636066A (en) |
UY (1) | UY29282A1 (en) |
WO (1) | WO2006066049A2 (en) |
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US8497072B2 (en) | 2005-11-30 | 2013-07-30 | Abbott Laboratories | Amyloid-beta globulomer antibodies |
US8691224B2 (en) | 2005-11-30 | 2014-04-08 | Abbvie Inc. | Anti-Aβ globulomer 5F7 antibodies |
US8877190B2 (en) | 2006-11-30 | 2014-11-04 | Abbvie Inc. | Aβ conformer selective anti-Aβ globulomer monoclonal antibodies |
US8895004B2 (en) | 2007-02-27 | 2014-11-25 | AbbVie Deutschland GmbH & Co. KG | Method for the treatment of amyloidoses |
US8987419B2 (en) | 2010-04-15 | 2015-03-24 | AbbVie Deutschland GmbH & Co. KG | Amyloid-beta binding proteins |
US9146244B2 (en) | 2007-06-12 | 2015-09-29 | Ac Immune S.A. | Polynucleotides encoding an anti-beta-amyloid monoclonal antibody |
US9176150B2 (en) | 2003-01-31 | 2015-11-03 | AbbVie Deutschland GmbH & Co. KG | Amyloid beta(1-42) oligomers, derivatives thereof and antibodies thereto, methods of preparation thereof and use thereof |
US9221900B2 (en) | 2010-07-30 | 2015-12-29 | Ac Immune S.A. | Methods for identifying safe and functional humanized antibodies |
US9403902B2 (en) | 2007-10-05 | 2016-08-02 | Ac Immune S.A. | Methods of treating ocular disease associated with amyloid-beta-related pathology using an anti-amyloid-beta antibody |
RU2724190C2 (en) * | 2014-02-08 | 2020-06-23 | Дженентек, Инк. | Methods of treating alzheimer's disease |
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CA2590337C (en) | 2004-12-15 | 2017-07-11 | Neuralab Limited | Humanized amyloid beta antibodies for use in improving cognition |
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AR051528A1 (en) | 2007-01-17 |
EP1838854A2 (en) | 2007-10-03 |
PE20061152A1 (en) | 2006-10-13 |
US7625560B2 (en) | 2009-12-01 |
ES2396555T3 (en) | 2013-02-22 |
TW200636066A (en) | 2006-10-16 |
UY29282A1 (en) | 2006-06-30 |
EP1838854B1 (en) | 2012-10-31 |
WO2006066049A2 (en) | 2006-06-22 |
US20060165682A1 (en) | 2006-07-27 |
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