WO2006079797A3 - Apparatus for measurement of analyte concentration - Google Patents
Apparatus for measurement of analyte concentration Download PDFInfo
- Publication number
- WO2006079797A3 WO2006079797A3 PCT/GB2006/000243 GB2006000243W WO2006079797A3 WO 2006079797 A3 WO2006079797 A3 WO 2006079797A3 GB 2006000243 W GB2006000243 W GB 2006000243W WO 2006079797 A3 WO2006079797 A3 WO 2006079797A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- measurement
- waveguide
- outputting
- analyte
- body region
- Prior art date
Links
- 238000005259 measurement Methods 0.000 title abstract 5
- 239000012491 analyte Substances 0.000 title abstract 3
- 230000003287 optical effect Effects 0.000 abstract 3
- 238000002835 absorbance Methods 0.000 abstract 2
- 210000000746 body region Anatomy 0.000 abstract 2
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000008103 glucose Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/55—Specular reflectivity
- G01N21/552—Attenuated total reflection
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
- G01N21/314—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry with comparison of measurements at specific and non-specific wavelengths
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
- G01N21/35—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
- G01N21/35—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light
- G01N21/359—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light using near infrared light
Abstract
Apparatus for measuring an analyte such as glucose comprises heated ribbon as an IR source (1) outputting IR light in two opposed directions, an ATR waveguide (4) , having a surface for forming an interface with a body region such as skin, hollow waveguide collimators (2) and (5) , and detectors (3) and (6) for each for measurement and reference wavelength bands outputting an optical absorbance d for the measurement band and an optical absorbance c for the reference band, and producing a time dependant output of the concentration g of said analyte calculated as where A and b/a are constants for a given set of conditions of use, and b and a corresponding to measures d and c respectively, but are determined with water rather than said body region in contact with said optical waveguide surface. Collimator (5) and detector (6) view the waveguide (4) at an adjustable angle α. The effect of temperature on the measurement is compensated for by a reading obtained from a temperature sensor (8) . A final value for g is obtained by applying a predictive algorithm to measurements taken at time intervals .
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0501826.2A GB0501826D0 (en) | 2005-01-28 | 2005-01-28 | Apparatus for measurement of analyte concentration |
GB0501826.2 | 2005-01-28 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2006079797A2 WO2006079797A2 (en) | 2006-08-03 |
WO2006079797A3 true WO2006079797A3 (en) | 2006-10-05 |
Family
ID=34307635
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/GB2006/000243 WO2006079797A2 (en) | 2005-01-28 | 2006-01-25 | Apparatus for measurement of analyte concentration |
Country Status (2)
Country | Link |
---|---|
GB (1) | GB0501826D0 (en) |
WO (1) | WO2006079797A2 (en) |
Cited By (4)
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---|---|---|---|---|
US8647489B2 (en) | 2005-09-30 | 2014-02-11 | Bayer Healthcare Llc | Gated voltammetry devices |
US8877035B2 (en) | 2005-07-20 | 2014-11-04 | Bayer Healthcare Llc | Gated amperometry methods |
US9005527B2 (en) | 2006-10-24 | 2015-04-14 | Bayer Healthcare Llc | Transient decay amperometry biosensors |
US9410917B2 (en) | 2004-02-06 | 2016-08-09 | Ascensia Diabetes Care Holdings Ag | Method of using a biosensor |
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RU2455925C2 (en) | 2006-02-27 | 2012-07-20 | БАЙЕР ХЕЛТКЭА ЭлЭлСи | Determination of investigated substance with correction to temperature for systems of biosensors |
US7966859B2 (en) | 2006-05-03 | 2011-06-28 | Bayer Healthcare Llc | Underfill detection system for a biosensor |
WO2009076302A1 (en) | 2007-12-10 | 2009-06-18 | Bayer Healthcare Llc | Control markers for auto-detection of control solution and methods of use |
WO2009108239A2 (en) | 2007-12-10 | 2009-09-03 | Bayer Healthcare Llc | Slope-based compensation |
MX2011005864A (en) | 2008-12-08 | 2011-06-20 | Bayer Healthcare Llc | Biosensor system with signal adjustment. |
EP2259048A1 (en) | 2009-06-03 | 2010-12-08 | Koninklijke Philips Electronics N.V. | Measuring reflectance using waveguide for coupling light to larger volume of sample |
CA2776332C (en) | 2009-11-10 | 2018-05-01 | Bayer Healthcare Llc | Underfill recognition system for a biosensor |
MX2012010860A (en) | 2010-03-22 | 2013-03-05 | Bayer Healthcare Llc | Residual compensation for a biosensor. |
RU2566382C2 (en) | 2010-06-07 | 2015-10-27 | БАЙЕР ХЕЛТКЭА ЭлЭлСи | Control system of insufficient filling for biosensor |
WO2011156152A1 (en) | 2010-06-07 | 2011-12-15 | Bayer Healthcare Llc | Slope-based compensation including secondary output signals |
KR101951971B1 (en) * | 2011-06-07 | 2019-02-25 | 메저먼트 스페셜티스, 인크. | Optical sensing device for fluid sensing and methods therefor |
ES2663097T3 (en) | 2011-09-21 | 2018-04-11 | Ascensia Diabetes Care Holdings Ag | Biosensor with error compensation |
WO2015030832A1 (en) * | 2013-08-31 | 2015-03-05 | Pandata Research Llc | Integrated optoelectronic module for physiological measurements and methods of use of the module |
WO2015167417A1 (en) * | 2014-04-08 | 2015-11-05 | Pandata Research Llc | Optical measurement system having an integrated internal reflection element and array detector |
WO2015156778A1 (en) * | 2014-04-08 | 2015-10-15 | Pandata Research Llc | Optical measurement system having an integrated internal reflection element and a plurality of array detectors |
WO2015156777A1 (en) * | 2014-04-08 | 2015-10-15 | Pandata Research Llc | Optical measurement system having an integrated internal reflection element and array detector |
US10806385B2 (en) | 2015-01-21 | 2020-10-20 | National Institutes For Quantum And Radiological Science And Technology | Device for measuring concentration of substance in blood, and method for measuring concentration of substance in blood |
KR102115105B1 (en) * | 2015-11-23 | 2020-05-26 | 에프. 호프만-라 로슈 아게 | Method and apparatus for determining the concentration of analyte in body fluids |
WO2018122319A1 (en) * | 2016-12-30 | 2018-07-05 | Swiss Spectral Ag | Device and method for the non-invasive determination of analytes |
ES2774983B2 (en) | 2019-01-22 | 2021-06-10 | Univ Sevilla | PORTABLE DEVICE AND METHOD FOR NON-INVASIVE ESTIMATION OF GLUCOSE LEVEL IN BLOOD |
JP7438774B2 (en) * | 2020-02-05 | 2024-02-27 | アズビル株式会社 | measuring device |
WO2023060953A1 (en) * | 2021-10-12 | 2023-04-20 | 深圳硅基传感科技有限公司 | Sensor and method for obtaining analyte concentration while taking into consideration temperature compensation |
CN114878492A (en) * | 2022-06-02 | 2022-08-09 | 西北核技术研究所 | Hyperspectral light source scanning interval selection method based on temperature sensitive factor |
Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0160768A1 (en) * | 1984-05-04 | 1985-11-13 | Kurabo Industries Ltd. | Spectrophotometric apparatus for the non-invasive determination of glucose in body tissues |
WO1992017765A1 (en) * | 1991-03-28 | 1992-10-15 | Johnson & Johnson Professional Products Limited | Method and apparatus for glucose concentration monitoring |
US5553613A (en) * | 1994-08-17 | 1996-09-10 | Pfizer Inc. | Non invasive blood analyte sensor |
WO2001079818A2 (en) * | 2000-04-12 | 2001-10-25 | Medoptix, Inc. | Infrared atr glucose measurement system |
US20030023152A1 (en) * | 2001-04-11 | 2003-01-30 | Abbink Russell E. | System for non-invasive measurement of glucose in humans |
US20030031597A1 (en) * | 2001-08-03 | 2003-02-13 | Waseda University | Apparatus for measuring glucose concentration |
WO2004091403A1 (en) * | 2003-04-15 | 2004-10-28 | Optiscan Biomedical Corporation | Sample element with barrier material |
-
2005
- 2005-01-28 GB GBGB0501826.2A patent/GB0501826D0/en not_active Ceased
-
2006
- 2006-01-25 WO PCT/GB2006/000243 patent/WO2006079797A2/en not_active Application Discontinuation
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0160768A1 (en) * | 1984-05-04 | 1985-11-13 | Kurabo Industries Ltd. | Spectrophotometric apparatus for the non-invasive determination of glucose in body tissues |
WO1992017765A1 (en) * | 1991-03-28 | 1992-10-15 | Johnson & Johnson Professional Products Limited | Method and apparatus for glucose concentration monitoring |
US5553613A (en) * | 1994-08-17 | 1996-09-10 | Pfizer Inc. | Non invasive blood analyte sensor |
WO2001079818A2 (en) * | 2000-04-12 | 2001-10-25 | Medoptix, Inc. | Infrared atr glucose measurement system |
US20030023152A1 (en) * | 2001-04-11 | 2003-01-30 | Abbink Russell E. | System for non-invasive measurement of glucose in humans |
US20030031597A1 (en) * | 2001-08-03 | 2003-02-13 | Waseda University | Apparatus for measuring glucose concentration |
WO2004091403A1 (en) * | 2003-04-15 | 2004-10-28 | Optiscan Biomedical Corporation | Sample element with barrier material |
Non-Patent Citations (2)
Title |
---|
KEN-ICHIRO KAJIWARA: "SPECTROSCOPIC QUANTITATIVE ANALYSIS OF BLOOD GLUCOSE BY FOURIER TRANSFORM INFRARED SPECTROSCOPY WITH AN ATTENUATED TOTAL REFLECTIONPRISM", MEDICAL PROGRESS THROUGH TECHNOLOGY, SPRINGER VERLAG. BERLIN, DE, vol. 18, no. 3, January 1992 (1992-01-01), pages 181 - 189, XP000331119, ISSN: 0047-6552 * |
SIMHI R ET AL: "Blood diagnostics using fiberoptic evanescent wave spectroscopy and neural networks analysis", SENSORS AND ACTUATORS B, ELSEVIER SEQUOIA S.A., LAUSANNE, CH, vol. 42, no. 3, August 1997 (1997-08-01), pages 157 - 161, XP004100260, ISSN: 0925-4005 * |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9410917B2 (en) | 2004-02-06 | 2016-08-09 | Ascensia Diabetes Care Holdings Ag | Method of using a biosensor |
US8877035B2 (en) | 2005-07-20 | 2014-11-04 | Bayer Healthcare Llc | Gated amperometry methods |
US8647489B2 (en) | 2005-09-30 | 2014-02-11 | Bayer Healthcare Llc | Gated voltammetry devices |
US9110013B2 (en) | 2005-09-30 | 2015-08-18 | Bayer Healthcare Llc | Gated voltammetry methods |
US9005527B2 (en) | 2006-10-24 | 2015-04-14 | Bayer Healthcare Llc | Transient decay amperometry biosensors |
Also Published As
Publication number | Publication date |
---|---|
WO2006079797A2 (en) | 2006-08-03 |
GB0501826D0 (en) | 2005-03-09 |
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