WO2006080113A1

WO2006080113A1 - Medical appliance for treating inside of biological duct

Info

Publication number: WO2006080113A1
Application number: PCT/JP2005/018665
Authority: WO
Inventors: Satoshi Saito; Daisuke Kawabe
Original assignee: Nihon University; Ir Medical Laboratory Co., Ltd.
Priority date: 2005-01-26
Filing date: 2005-10-07
Publication date: 2006-08-03
Also published as: JPWO2006080113A1

Abstract

A medical appliance for treating the inside of a biological duct enabling an increase in manufacturing efficiency and a reduction in cost. A filter part (2) is formed at a position along the axial direction of a cylindrical insertion tube (1) formed of a shape memory alloy. The filter part (2) is formed by forming a plurality of openings (4) in the peripheral surface of the insertion tube (1) by laser cutting, contracting the filter part formed portion (2a) of the insertion tube (1) in the axial direction of the insertion tube (1), and in the state of each filter formed part (1a) of the insertion tube (1)formed between the opening parts (4) deflected in the radial outer direction of the insertion tube (1), storing the shape of the filter part in each filter formed part (1a).

Description

Specification

Intravascular treatment device

Technical field

The present invention relates to an in-vivo treatment device that treats the inside of a living body by capturing and removing foreign matter in the living body.

Background art

Conventionally, when treating the inside of a biological tube such as a blood vessel, many methods for capturing and removing foreign matters such as a thrombus from the wall surface of the biological tube have been used. Here, when a blood vessel is assumed as the living body tube and a thrombus is assumed as the foreign body, the thrombus removed from the wall surface of the blood vessel is carried by the blood flow, and there is a possibility that the downstream blood vessel may be blocked.

In order to cope with such a problem, there is a treatment method in which a medical treatment device in a living tube as described in Patent Document 1 is inserted into a blood vessel, and a thrombus in the blood vessel is captured and removed.

[0003] The in-vivo treatment device described in Patent Document 1 connects three or more alloy wires formed in a straight line to each other at both front and rear ends, and removes intermediate portions of the plurality of alloy wires. It is provided with a filter portion that is configured to be sunk in the radial direction and arranged along a substantially football-like boundary surface. Then, for example, the thrombus in the blood vessel is captured and removed by the trapping portion formed of an umbrella-like cover formed by covering the outer surface of the filter portion, for example, from the front end portion to almost the middle with an elastic film.

[0004] Here, the in-vivo treatment device is inserted into an induction conduit having catheter force with the filter portion folded, and then inserted into the blood vessel together with the guide tube. Then, after reaching the target location, such as the lesion site, the front end portion of the in-vivo treatment device is sent forward in the guide tube force, and the guide tube force is also exerted, and the filter portion is projected outward. The thrombus is captured and removed from the blood vessel by the filter unit.

However, the filter part provided in the in-vivo treatment device described in Patent Document 1 may become clogged during the operation or immediately block the blood flow in the blood vessel. Therefore, in order to deal with this problem, there is an in-vivo treatment device in which the filter portion is composed of a plurality of support lines and a basket-like mesh body. In a living tube provided with such a filter unit If it is a treatment tool, it is possible to remove the thrombus without blocking the blood flow in the blood vessel.

Patent Document 1: JP-A-2001-212152

Disclosure of the invention

[0005] However, the filter portion provided in the in-vivo treatment device as described above is formed in a basket shape by weaving a mesh body having a shape memory alloy force into a plurality of support wires. For this reason, it takes time to manufacture the filter part, and the manufacturing efficiency of the in-vivo treatment device is reduced, and the cost of the in-vivo treatment device is increased.

In addition, the filter part is often formed of a shape memory alloy such as a nickel'titanium alloy, and is often subjected to shape memory processing in the state of projecting in the outer diameter direction. It is difficult to bond by. For this reason, when connecting the filter part and other parts of the treatment device such as a wire such as a wire, it is necessary to caulk the front and rear ends of the filter part with a metal or the like, and the step formed in the caulking part However, this contributes to the removal of the filter unit from the in-vivo treatment device. If the filter part is detached from the in-vivo treatment device in the blood vessel, the detached filter part is carried by the blood flow, and there is a possibility that the narrower downstream blood vessel is blocked.

[0006] The present invention has been made paying attention to the above-described problems, and can improve the manufacturing efficiency and reduce the cost, and can prevent the separation of the filter part. It is an object to provide a treatment tool.

In order to solve the above-mentioned problem, the invention described in claim 1 of the present invention is an in-vivo treatment device that captures and removes a foreign substance in the in-vivo tube by a filter portion protruding in the outer diameter direction,

An insertion tube made of a shape memory alloy to be inserted into the biological tube;

In the insertion tube, at least one place along the axial direction of the insertion tube forms the filter part,

The filter section has a plurality of openings or slits formed in the peripheral surface of the insertion tube, and is formed between the plurality of openings or slits by contracting the filter section forming position of the insertion tube in the axial direction. In the state where the filtered filter part is folded in the outer diameter direction of the insertion tube The shape is memorized and formed.

[0007] According to the present invention, a plurality of openings or slits are formed on the peripheral surface of the insertion tube, and each filter component formed between the plurality of openings or slits is formed in the outer diameter direction of the insertion tube. In this state, by storing the shape in each filter component, and forming a filter unit that captures foreign substances in the living tube, the manufacturing efficiency of the in-vivo treatment device can be improved and the cost can be reduced.

Further, since the insertion tube and the filter portion are a single body, the filter portion is prevented from being detached from the insertion tube in the living body tube. Further, since the insertion tube and the filter portion are a single body, no step is formed at the coupling portion between the filter portion and the other components, so that the diameter of the insertion tube can be reduced.

[0008] Further, the shape of the insertion tube is made of a shape memory alloy, and the shape of each filter component is stored in a state where each filter component is wound in the outer diameter direction of the insertion tube. Even when the filter is folded for a long time, the shape of the filter section is reliably restored.

As the shape memory alloy, a superelastic alloy such as a nickel titanium alloy is suitable. Further, as a method of forming the opening or slit on the peripheral surface of the insertion tube, a method using a laser cut is suitable.

[0009] Next, of the present invention, the invention described in claim 2 is the invention described in claim 1, in which at least one of the opening and the slit extends along a longitudinal direction of the insertion tube. It is characterized by extending!

According to the present invention, by forming the plurality of openings or slits in a shape extending along the longitudinal direction of the insertion tube, the shape of the filter constituent portion is a shape suitable for the filter portion to capture foreign matter in the biological tube. It is formed to become.

[0010] Next, of the present invention, the invention described in claim 3 is the invention described in claim 1, wherein the filter portion is formed on a distal side which is a distal end side of the insertion tube. And a transmission part formed on the proximal side, which is the proximal end side of the insertion tube,

The opening of the capturing part has a smaller opening area than the opening of the transmission part.

According to the present invention, in a living body tube, it passes through a transmission part formed on the proximal side of the insertion tube. The trapped foreign matter is captured by the capture part that is formed on the distal side of the insertion tube and has an opening area that is narrower than the opening part of the transmission part. To do.

[0011] Next, of the present invention, the invention described in claim 4 is the invention described in claim 3, wherein the opening of the transmission portion extends along the longitudinal direction of the insertion tube. It is characterized by being.

According to the present invention, since the opening of the permeation part has a shape extending along the longitudinal direction of the insertion tube, the force of the filter component formed in each opening of the permeation part. It is formed in a shape suitable for passing through.

[0012] Next, of the present invention, the invention according to claim 5 is the invention according to any one of claims 1 to 4, wherein the wire is movably inserted into the insertion tube. And the wire passes through the filter part and is joined to a distal side part which is the distal end side of the insertion tube.

According to the present invention, since the distal side portion of the insertion tube and the wire are connected to each other through the filter portion in the insertion tube, the shape of the filter portion becomes an appropriate shape for capturing the foreign matter in the biological tube. Retained.

[0013] Next, among the present inventions, the invention described in claim 6 is an in-vivo treatment device that captures and removes foreign matter in a living body tube by a filter portion protruding in an outer diameter direction, and the living body An insertion tube made of a shape memory alloy to be inserted into the tube, and a wire that is inserted into the insertion tube so as to move.

The filter part is cut into a spiral shape along the axial direction of the insertion tube on the peripheral surface of the insertion tube to form a cutting part, and the filter component formed between the cutting parts is disposed outside the insertion pipe. The shape is memorized and formed in the expanded state in the radial direction,

The wire passes through the filter part and is joined to a distal side part which is the distal end side of the insertion tube.

[0014] According to the present invention, the peripheral surface of the insertion tube is spirally cut along the axial direction of the insertion tube. By forming a cut portion and storing the shape in each filter component in a state where each filter component formed between the cut portions is expanded in the outer diameter direction of the insertion tube, foreign matter in the living body tube Therefore, it is possible to improve the manufacturing efficiency and reduce the cost of the in-vivo treatment device.

In addition, the insertion tube is made of a shape memory alloy, and the shape of each filter component is stored in a state in which each filter component is expanded in the outer diameter direction of the insertion tube, so that the filter unit is folded for a long time. Even in the state, the shape of the filter portion is reliably restored.

[0015] In addition, since the insertion tube is connected to the distal side portion of the insertion tube and the wire through the filter portion, the shape of the filter portion is maintained in an appropriate shape for capturing foreign matter in the living tube. Is done.

As a method for forming the cut portion on the peripheral surface of the insertion tube, a laser cut method is suitable.

Next, of the present invention, the invention described in claim 7 is the invention described in claim 5 or 6, wherein the one end of the wire is connected to the proximal end side of the insertion tube. The near end force is protruding.

[0016] According to the present invention, the shape of the filter portion can be changed to an arbitrary shape by moving a portion protruding from the proximal end of the insertion tube of the wire inserted into the insertion tube. Is possible.

Brief Description of Drawings

[0017] FIG. 1 is a diagram showing an in-vivo treatment device according to a first embodiment of the present invention.

FIG. 2 is a view showing the in-vivo treatment device according to the first embodiment of the present invention.

FIG. 3 is a view showing a state of foreign body removal work in a living body tube using the in-vivo treatment device of the first embodiment of the present invention.

FIG. 4 is a diagram showing a modification of the first embodiment of the present invention.

FIG. 5 is a diagram showing a modification of the first embodiment of the present invention.

FIG. 6 is a view showing a modification of the first embodiment of the present invention.

FIG. 7 is a view showing an in-vivo treatment device according to a second embodiment of the present invention.

FIG. 8 is a view showing an in-vivo treatment device according to a second embodiment of the present invention. [9] FIG. 9 is a view showing an in-vivo treatment device according to a third embodiment of the present invention.

[10] FIG. 10 is a view showing an in-vivo treatment device according to a third embodiment of the present invention.

FIG. 11 is a cross-sectional view taken along line AA in FIG.

Explanation of symbols

1 Insertion tube

2 Filter section

4 opening

6 Guide tube

8 blood vessels

10 Thrombus

12 Trapping part

14 Transmission part

16 wires

18 Cutting part

20 Cavity

22 Edge

Center axis of CL insertion tube

BEST MODE FOR CARRYING OUT THE INVENTION

Next, a first embodiment of the present invention will be described with reference to the drawings.

First, the configuration of the present embodiment will be described with reference to FIG. 1 and FIG.

The in-vivo treatment device of this embodiment includes an insertion tube 1 as shown in FIG.

As shown in FIG. 1 (a), the insertion tube 1 has a cylindrical shape and is made of a shape memory alloy having flexibility. In the present embodiment, a case where a −kel ′ titanium alloy is used as the shape memory alloy will be described as an example.

[0020] In addition, the insertion tube 1 has a filter portion that captures a foreign substance in the living body tube at one place along the axial direction of the insertion tube 1.

Below, the formation method of a filter part is demonstrated.

First, the peripheral surface of the insertion tube 1 is opened by laser cutting, and a plurality of surfaces are inserted into the peripheral surface of the insertion tube 1. Opening 4 is formed. The shape of each opening 4 is a shape extending along the central axis CL of the insertion tube 1. In addition, each opening 4 is set so that the intervals between adjacent openings 4 are equal. In this embodiment, as shown in FIG. 1B, which is a development view of FIG. 1A, a case where four openings 4 are formed in the insertion tube 1 will be described as an example.

Next, as shown in FIG. 2, the filter configuration in which the filter portion forming position 2a of the insertion tube 1 is contracted in the axial direction of the insertion tube 1 and is formed between the openings 4 in the insertion tube 1 In a state where the portion la is constricted in the outer diameter direction of the insertion tube 1, the shape is stored in the filter constituent portion la, and the formation of the filter portion 2 is completed.

By the above-described method, the circumferential force of the insertion tube 1 is externally applied to one place along the axial direction of the insertion tube 1 by each filter component la shaped in the outer diameter direction from the circumferential surface of the insertion tube 1. A filter portion 2 projecting in the radial direction is formed. When each filter component la receives a load in the inner diameter direction of the insertion tube 1, the filter portion forming position 2 a extends in the axial direction of the insertion tube 1 and has a spring in the outer diameter direction of the insertion tube 1. However, when it is displaced in the inner diameter direction of the insertion tube 1 and released from the load in the inner diameter direction of the insertion tube 1, the shape is restored to the shape of the insertion tube 1 in the outer diameter direction.

Next, operations and effects of the present embodiment will be described with reference to FIG. In the present embodiment, a case where a biological tube is a blood vessel and a foreign substance in the biological tube is a thrombus will be described as an example.

The intravascular blood clot removal operation using the in-vivo treatment device of this embodiment is performed according to the following procedure.

First, the insertion tube 1 is inserted into a guide tube 6 such as a catheter catheter, the filter portion forming position 2a extends in the axial direction of the insertion tube 1, and each filter component la extends in the outer diameter direction of the insertion tube 1. It is assumed that the insertion tube 1 is displaced in the inner diameter direction while having a spring. Then, the guide tube 6 is inserted into the blood vessel 8 from the distal end side, and after the distal end of the guide tube 6 has passed through the thrombus 10, the distal force insertion tube 1 of the guide tube 6 is pushed out as shown in FIG. At this time, since the shape is stored in the filter portion 2 in a state where the filter constituting portion la is held in the outer diameter direction of the insertion tube 1, if the distal end force insertion tube 1 of the guide tube 6 is pushed out, the filter portion 2 The shape of the portion 2 is restored, and the filter portion 2 is formed in the blood vessel 8 between the thrombus 10 and the downstream side in the blood vessel 8. Next, after moving the guide tube 6 to the upstream side of the blood vessel 8, the insertion tube 1 is moved to the upstream side of the blood vessel 8 while rotating the insertion tube 1, and the filter portion 2 is moved from the downstream side of the blood vessel 8 to the thrombus 10. Pass through the position. The insertion tube 1 may be moved upstream of the blood vessel 8 without rotating. At this time, the thrombus 10 is entangled by the filter portion 2 that has passed through the position of the thrombus 10 from the downstream side of the blood vessel 8, and the entangled thrombus 10 is captured by each filter component la.

Then, without moving the guide tube 6, only the insertion tube 1 is moved to the upstream side of the blood vessel 8, the insertion tube 1 is stored in the guide tube 6, and each filter component la has an outer diameter of the insertion tube 1. After the guide tube 6 and the insertion tube 1 are pulled out from the blood vessel 8, the removal of the thrombus 10 in the blood vessel 8 is completed. .

[0024] Therefore, in the in-vivo treatment device of the present embodiment, after forming a plurality of openings 4 on the peripheral surface of the insertion tube 1, the filter portion forming position 2a of the insertion tube 1 is set to the axis of the insertion tube 1. The filter portion 2 can be formed by causing the filter component portion la to store the shape in a state where the filter component portion la is contracted in the direction and the filter component portion la is constricted in the outer diameter direction of the insertion tube 1. In addition, it is possible to improve the manufacturing efficiency and reduce the manufacturing cost of the in-vivo treatment device.

In addition, since the insertion tube 1 and the filter unit 2 are a single body in the in-vivo treatment device of the present embodiment, the removal of the filter unit 2 from the insertion tube 1 in the blood vessel 8 is prevented, and The safety of removing foreign substances in the body tube is improved. In addition, since it is formed in a conventional in-vivo treatment device, a connecting portion between the filter portion 2 and other components such as a forceps portion is not formed, and the filter portion 2 and other components are not formed. Since no step is formed, it is possible to reduce the diameter of the insertion tube 1, and it is possible to use an in-vivo treatment tool in a thinner living tube.

[0025] Further, in the in-vivo treatment device of the present embodiment, the inside of the insertion tube 1 can be a passage through which a liquid such as a thrombolytic agent can pass. For this reason, even if the clot 10 is clogged by the thrombus 10 during the removal of the thrombus 10, the thrombolytic agent is pumped from the outside of the insertion tube 1 to the filter unit 2 to remove the filter unit 2. It is possible to eliminate clogging of 2. Therefore, the thrombus 10 in the blood vessel 8 can be removed more effectively.

Further, in the case of the in-vivo treatment device of the present embodiment, the insertion tube 1 is made of a shape memory alloy. Since the shape is stored in a state where the filter portion 2 is formed, the insertion tube 1 is inserted into the guide tube 6 even when the insertion tube 1 is inserted into the guide tube 6 for a long time with the filter portion 2 folded. The shape of the filter part 2 is reliably restored when it comes out of the box.

[0026] In the in-vivo treatment device of the present embodiment, the force formed in the shape of each opening 4 along the central axis CL of the insertion tube 1 is not limited to this. That is, as shown in FIGS. 4 and 5, each opening 4 may be formed at an arbitrary angle with respect to the central axis CL of the insertion tube 1. Further, each opening 4 may have a shape extending while meandering along the longitudinal direction of the insertion tube 1. Here, each opening 4 formed in the insertion tube 1 shown in FIG. 4 (b), which is a development view of FIGS. 4 (a) and 4 (a), is inserted into the insertion tube 1 as shown in the figure. It is formed with an angle of 10 degrees with respect to the central axis CL. In addition, each opening 4 formed in the insertion tube 1 shown in FIG. 5 (b), which is an exploded view of FIG. 5 (a) and FIG. 5 (a), is inserted as shown in the figure. It is formed with an angle of 19 degrees with respect to the central axis CL of the tube 1. In this way, each opening 4 is formed at an arbitrary angle with respect to the central axis CL of the insertion tube 1, thereby complicating the shape of the filter unit 2. Increases efficiency.

[0027] The shape of the opening 4 may be a wide variety of shapes as shown in Figs. 6 (a) to 6 (h). That is, the shape of the opening 4 may be any shape as long as the filter portion 2 is formed in a shape capable of capturing foreign matter in the living body tube. Although not particularly shown, the opening 4 may be a slit. In this case, all the openings 4 may be slits, or the openings 4 and the slits may be mixed.

Further, in the in-vivo treatment device of the present embodiment, the intervals between the adjacent openings 4 are set to be equal intervals, but the present invention is not limited to this, and the filter unit 2 is formed so as to capture foreign substances in the in-vivo tube. If it is an interval,

[0028] Further, although the in-vivo treatment device of the present embodiment is configured to include only the insertion tube 1, it is not limited to this. That is, a flexible wire may be movably inserted into the insertion tube 1 and the wire may be connected to the distal side portion of the insertion tube 1 through the filter unit 2. In this case, the shape force of the filter unit 2 is held in an appropriate shape for capturing the thrombus 10. Further, the end of the wire may be configured such that the proximal end force of the insertion tube 1 also protrudes. In this case, it is possible to change the shape of the filter portion 2 to an arbitrary shape by moving the portion of the wire that also projects the proximal end force of the insertion tube 1. Further, an introduction member having a shape that facilitates insertion of the insertion tube 1 into the blood vessel 8 such as a shape that decreases in diameter toward the distal end may be connected to the distal end portion of the insertion tube 1. ,.

[0029] In the in-vivo treatment device of the present embodiment, the filter unit 2 is formed only at one location along the axial direction of the insertion tube 1. However, the present invention is not limited to this, and the axial direction of the insertion tube 1 is not limited thereto. Filter 2 at multiple locations along the line.

In the in-vivo treatment device of the present embodiment, the insertion tube 1 has a cylindrical shape. However, the present invention is not limited to this, and a passage through which liquid can pass is formed inside the insertion tube 1. For example, it may be formed in a substantially cylindrical shape whose cross section is elliptical.

[0030] Further, in the in-vivo treatment device of the present embodiment, when the filter unit 2 is formed, each filter component la is placed in a state in which each filter component la is bent in the outer diameter direction of the insertion tube 1. The force that memorizes the shape is not limited to this. That is, when forming the filter portion 2, the shape of the entire insertion tube 1 may be stored in a state where each filter component la is held in the outer diameter direction of the insertion tube 1.

In this embodiment, the case where the blood vessel 8 is the blood vessel 8 has been described as an example. However, the present invention is not limited to this and can be applied to other biological tubes such as a bile duct. In this embodiment, the case where the foreign substance in the living body tube is the thrombus 10 has been described as an example. However, the present invention is not limited to this and can be applied to other foreign substances such as gallstones.

Next, a second embodiment of the present invention will be described with reference to FIG. 7 and FIG. In addition, the same code | symbol is attached | subjected about the structure similar to 1st embodiment mentioned above, and the description is abbreviate | omitted. The insertion tube 1 provided in the in-vivo treatment device of the present embodiment has the same configuration as that of the first embodiment described above except for the configuration of the filter unit 2.

As shown in FIG. 7, which is a development view of the insertion tube 1, the filter portion 2 includes a capture portion 12 formed on the distal side that is the distal end side of the insertion tube 1 and a proximal end side of the insertion tube 1. And a transmission part 14 formed on the distal side.

Hereinafter, a method for forming the filter portion 2 will be described. First, the peripheral surface of the insertion tube 1 is opened by laser cutting to form a plurality of openings 4 a in the capturing part 12 and a plurality of openings 4 b in the transmission part 14.

Next, each opening 4a of the trapping part 12 is contracted in the axial direction of the insertion pipe 1 at the filter part forming position 2a of the insertion pipe 1, and the trapping part constituting part 12a formed between the openings 4a is inserted. In a state where the tube 1 is squeezed in the outer diameter direction, a rectangular shape is formed by one laser cut so that the capturing portion constituting portion 12a has a mesh shape. Here, each opening 4a is formed such that its opening area is narrower than the opening area of each opening 4b of the transmission part 14.

[0033] Further, the opening 4b of the transmission portion 14 is contracted in the axial direction of the insertion tube 1 at the filter portion forming position 2a of the insertion tube 1, and the transmission portion constituting portion 14a formed between the openings 4b is provided. Formed by laser cutting so that the transmission portion constituting portion 14a formed between the openings 4b is formed in a columnar shape along the axial direction of the insertion tube 1 in a state where the insertion tube 1 is constricted in the outer diameter direction. . The shape of each opening 4b extends along the axial direction of the insertion tube 1, and the width along the circumferential direction of the insertion tube 1 gradually increases the proximal force of the insertion tube 1 toward the distal side. The shape becomes narrower.

Then, as shown in FIG. 8, the filter portion forming position 2a of the insertion tube 1 is contracted in the axial direction of the insertion tube 1, and the capturing portion constituting portion 12a and the transmission portion constituting portion 14a are connected to the insertion tube 1. The shape is stored in the capturing part constituting part 12a and the transmissive part constituting part 14a in a state where it is bent in the outer diameter direction, and the formation of the filter part 2 is completed.

By the above-described method, the insertion tube 1 is disposed at one place along the axial direction of the insertion tube 1 by the capturing portion constituting portion 12a and the transmission portion constituting portion 14a having a shape sandwiched from the peripheral surface of the insertion tube 1 in the outer diameter direction. A filter portion 2 is formed which projects in the outer diameter direction from the peripheral surface 1. When receiving part 12a and permeation part constituting part 14a are loaded in the inner diameter direction of insertion tube 1, filter part forming position 2a extends in the axial direction of insertion pipe 1, and outer diameter of insertion pipe 1 is increased. When it is displaced in the inner diameter direction of the insertion tube 1 while having a spring in the direction and the load force in the inner diameter direction of the insertion tube 1 is released, the shape of the insertion tube 1 is restored to the shape of the outer diameter.

Other configurations are the same as those of the first embodiment described above.

Next, the effect | action effect of this embodiment is demonstrated. Detailed description of the same operations and effects as those of the first embodiment described above will be omitted.

The intravascular blood clot removal operation using the in-vivo treatment device of this embodiment is performed according to the following procedure. Do along.

First, the insertion tube 1 is inserted into the guide tube, and the trapping portion constituting portion 12a and the transmitting portion constituting portion 14a are extended in the axial direction of the insertion tube 1 while the filter portion forming position 2a extends in the outer diameter direction of the insertion tube 1. It is assumed that the insertion tube 1 is displaced in the inner diameter direction while having a spring. Then, this guide tube is inserted into the living body tube at the distal end side force, and after the distal end of the guide tube passes through the foreign matter, the insertion tube 1 is pushed out from the distal end of the guide tube. At this time, since the shape is stored in the filter portion 2 with the capturing portion constituting portion 12a and the transmissive portion constituting portion 14a being squeezed in the outer diameter direction of the insertion tube 1, the tip force of the guide tube is also reduced. When 1 is pushed out, the shape of the filter portion 2 is restored, and the filter portion 2 is formed between the foreign substance and the downstream side in the biological tube in the biological tube.

Next, after moving the guide tube to the upstream side of the biological tube, the insertion tube 1 is moved to the upstream side of the biological tube, and the filter unit 2 passes through the position of the foreign substance from the downstream side of the biological tube. Let At this time, the foreign matter on the upstream side of the filter unit 2 passes through the transmission unit 14 and is captured by the capture unit 12.

Then, without moving the guide tube, only the insertion tube 1 is moved to the upstream side of the living body tube, the insertion tube 1 is stored in the guide tube, and the trapping portion constituting portion 12a and the transmitting portion constituting portion 14a are formed as filter portions. After the position 2a extends in the axial direction of the insertion tube 1 and is displaced in the inner diameter direction of the insertion tube 1 while having a spring in the outer diameter direction of the insertion tube 1, the guide tube and the insertion tube 1 are Withdrawing from the living body tube, the foreign substance removing operation in the living body tube is completed.

[0037] Therefore, in the in-vivo treatment device of the present embodiment, since the opening area of each opening 4a of the capturing unit 12 is narrower than the opening area of each opening 4b of the transmitting unit 14, the transmitting unit 14 is used. The foreign matter that has passed through is captured by the capturing unit 12 located on the downstream side in the biological tube, and the efficiency of the foreign matter removal work in the biological tube is improved.

Further, since each opening 4b of the transmission part 14 has an opening area larger than that of the opening 4a of the capturing part 12, it is possible to ensure a sufficient fluid flow in the living body tube.

[0038] Although not particularly illustrated, each opening 4a of the capturing part 12 has a different opening area, and the opening area of the opening 4a located on the distal end side of the insertion tube 1 is set to be proximal to the insertion tube 1. A configuration may be adopted in which the opening area of the opening 4a located on the end side is narrower.

Further, the in-vivo treatment device of the present embodiment is above the filter unit 2 in the in-vivo tube. Although the foreign substance on the flow side passes through the permeation section 14 and is captured and removed by the capture section 12, it is not limited thereto. That is, after the guide tube is moved to the upstream side of the biological tube, the insertion tube 1 is rotated and moved to the upstream side of the biological tube, and the filter unit 2 is passed through the position of the force foreign substance on the downstream side of the biological tube, A method of using the filter unit 2 that has passed through the position of the foreign substance from the downstream side of the biological tube may be used.

[0039] Other effects are the same as in the first embodiment described above.

Next, a third embodiment of the present invention will be described with reference to the drawings. In addition, the same code | symbol is attached | subjected and demonstrated about the structure similar to 1st and 2nd embodiment mentioned above. First, the configuration of this embodiment will be described with reference to FIGS.

As shown in FIG. 9, the in-vivo treatment device of the present embodiment includes an insertion tube 1 and a wire 16 that is movably inserted into the insertion tube 1.

[0040] The insertion tube 1 has a cylindrical shape and is formed of a flexible shape memory alloy.

In addition, the insertion tube 1 has a filter portion 2 that captures a foreign substance in the living body tube at one place along the axial direction of the insertion tube 1.

Hereinafter, a method for forming the filter portion 2 will be described.

First, a cutting portion 18 that is cut in a spiral shape along the axial direction of the insertion tube 1 is formed on the peripheral surface of the insertion tube 1 by laser cutting. Next, as shown in FIG. 10, in the insertion tube 1, the filter component la formed between the cut portions 18 is expanded in the outer diameter direction of the insertion tube 1. The shape is stored, and the formation of the filter unit 2 is completed.

[0041] Here, the shape of the filter portion 2 is a shape in which the distal side force of the insertion tube 1 also expands toward the proximal side of the insertion tube 1.

By the above-described method, at one location along the axial direction of the insertion tube 1, the outer diameter of the insertion tube 1 from the circumferential surface of the insertion tube 1 is increased by the filter component la having a shape expanded from the circumferential surface of the insertion tube 1 to the outer diameter direction. A filter part 2 projecting in the direction is formed. When receiving a load in the inner diameter direction of the insertion tube 1, the filter component la displaces in the inner diameter direction of the insertion tube 1 while having a spring in the outer diameter direction of the insertion tube 1, and moves toward the inner diameter direction of the insertion tube 1. When the load is released, the shape of the insertion tube 1 is restored to the shape of the outer diameter. [0042] The wire 16 is formed of a flexible wire, one end of which is connected to the distal side lb which is the distal end side of the insertion tube 1, and the other end 16a is the insertion tube. The proximal end lc force, which is the base end of 1, also protrudes. Here, one end of the wire 16 and the distal side lb are joined together by applying force together.

As shown in FIG. 11, a gap 20 is formed between the inner diameter surface Id of the insertion tube 1 and the wire 16.

Other configurations are the same as those in the first embodiment described above.

Next, the effect | action effect of this embodiment is demonstrated.

The in-vivo foreign body removal operation using the in-vivo treatment device of the present embodiment is performed according to the following procedure.

First, the portion of the wire 16 that also projects the proximal end lc force of the insertion tube 1 is moved to reduce the diameter of the filter component la in the inner diameter direction of the insertion tube 1. Next, the insertion tube 1 is inserted into the biological tube from the distal end side, and after the distal end of the insertion tube 1 has passed through the foreign matter, the shape of the filter unit 2 is restored, and the foreign matter and the downstream side of the biological tube in the biological tube. The filter part 2 is formed between the two. At this time, the shape of the filter portion 2 is memorized in a state where the diameter of the filter component la is expanded in the outer diameter direction of the insertion tube 1, so that the shape of the filter portion 2 is surely ensured in the living body tube. Restored.

[0044] Next, the insertion tube 1 is rotated and moved to the upstream side of the biological tube, and the filter unit 2 is passed through the position of the foreign substance on the downstream side of the biological tube. At this time, the foreign matter is entangled by the filter unit 2 that has passed through the position of the foreign matter from the downstream side of the biological tube, and the entangled foreign matter is captured by the filter component la.

Then, the insertion tube 1 is moved to the upstream side of the living body tube and pulled out from the living body tube, and the foreign substance removing operation in the living body tube is completed.

Therefore, in the in-vivo treatment device of the present embodiment, after forming the helical cut portion 18 along the axial direction of the insertion tube 1 on the peripheral surface of the insertion tube 1 by one laser cut, Since the filter part 2 can be formed by storing the shape in a state where the filter component la is expanded in the outer diameter direction of the insertion tube 1, the manufacturing efficiency of the in-vivo treatment device is improved. In addition, manufacturing costs can be reduced. Further, in the case of the in-vivo treatment device of the present embodiment, since the insertion tube 1 and the wire 16 are coupled by caulking the distal side portion lb of the insertion tube 1 and the wire 16, the conventional living body The forceps for connecting the filter portion 2 and other components, which have been formed in the intravascular treatment tool, are formed only on the distal side portion lb of the insertion tube 1. For this reason, the risk that the distal side portion lb of the insertion tube 1 and the filter portion 2 are detached from other components in the biological tube is reduced, and the safety of the foreign substance removal work in the biological tube is improved.

[0046] Further, in the in-vivo treatment device of the present embodiment, one end of the wire 16 is coupled to the distal side lb of the insertion tube 1, and the other end 16a of the wire 16 is It protrudes from the proximal end lc of the insertion tube 1. For this reason, the shape force of the filter unit 2 is held in a shape suitable for trapping foreign matter in the biological tube, and the work efficiency of the foreign matter removal work in the biological tube is improved. In addition, by moving the portion of the wire 16 that protrudes from the proximal end lc of the insertion tube 1, the shape of the filter unit 2 can be changed to an arbitrary shape, so that the foreign matter in the biological tube The work efficiency of the removal work is improved.

[0047] Further, in the in-vivo treatment device of the present embodiment, a passage through which a liquid such as a thrombolytic agent can pass through the void portion 20 formed between the inner diameter surface Id of the insertion tube 1 and the wire 16 is provided. It is possible to For this reason, since it is possible to send a liquid such as a thrombolytic agent from the proximal end lc of the insertion tube 1 into the living body tube via the filter unit 2, it is possible to more effectively remove foreign substances in the living tube. Is possible.

In the in-vivo treatment device of this embodiment, the insertion tube 1 is inserted into the insertion tube 1 while the filter component 1a has a spring in the outer diameter direction of the insertion tube 1 as in the first embodiment. Insert the guide tube into the living body tube from the distal end side after the foreign substance has passed through the foreign body, and then push the insertion tube 1 from the distal end of the guide tube. It is good also as a structure to take out.

[0048] In the in-vivo treatment device of the present embodiment, the shape of the filter unit 2 is a shape that expands from the distal side of the insertion tube 1 toward the proximal side of the insertion tube 1. The shape of the insertion tube 1 is not limited to a shape that expands toward the distal side of the insertion tube 1 from the proximal side of the insertion tube 1. Furthermore, in the in-vivo treatment device of the present embodiment, the force is such that the other end portion 16a of the wire 16 protrudes from the proximal end lc of the insertion tube 1. The wire is not limited to this. The other end 16a of 16 may be stored in the insertion tube 1!

[0049] Further, a chamfered portion may be provided on the peripheral edge 22 of the insertion tube 1 of the filter component la.

In this case, the risk of damaging the inside of the living body can be reduced in the foreign body removing work in the living body, and the safety of the removing work in the living body can be improved.

Other functions and effects are the same as those of the first embodiment described above.

[Example]

In creating an in-vivo treatment device having the same configuration as that described in the first and third embodiments described above, an opening and a cutting portion are formed by laser cutting on a part of the peripheral surface of the insertion tube. The work accuracy was verified.

[0050] First, an insertion tube having the same configuration as that described in the first embodiment was created. The insertion tube uses a nickel-titanium alloy pipe with a diameter of 0.458mm and a circumference of 1.438mm. A slit-shaped opening with a width of 0.03mm is parallel to the central axis of the insertion tube by laser cutting. 24 locations were formed. As a result, 24 filter components having a width of 0.02992 mm were formed in the insertion tube.

Next, an insertion tube having the same configuration as that described in the third embodiment was created. A nickel-titanium alloy pipe having an outer diameter of 0.4 mm and an inner diameter of 0.2 mm was used as the insertion tube, and a steel wire having an outer diameter of 0.18 mm was used as the wire. The insertion tube was provided with a laser cut to form a cut portion having a width of 50 m in a spiral shape and a width between adjacent cut portions of 200 μm.

[0051] Therefore, the insertion tube provided in the in-vivo treatment device of each embodiment described above can be created by forming an opening and a cut portion by laser cutting on a cylindrical nickel-titanium alloy pipe. It was confirmed that.

Industrial applicability

[0052] According to the present invention, it is possible to improve the production efficiency and cost of an in-vivo treatment device, and to prevent the filter unit from being disengaged from the in-vivo treatment device force within the in-vivo tube, so that the inside of the in-vivo tube can be prevented. Occlusion can be prevented.

Claims

The scope of the claims

[1] An in-vivo treatment device that captures and removes a foreign substance in a living body tube by a filter portion protruding in an outer diameter direction.

The filter section has a plurality of openings or slits formed in the peripheral surface of the insertion tube, and is formed between the plurality of openings or slits by contracting the filter section forming position of the insertion tube in the axial direction. An in-vivo treatment device, wherein a shape is stored and formed in a state in which the formed filter component is constricted in the outer diameter direction of the insertion tube.

[2] The in-vivo treatment device according to claim 1, wherein at least one of the opening and the slit extends along a longitudinal direction of the insertion tube.

[3] The filter portion includes a capturing portion formed on a distal side that is a distal end side of the insertion tube and a transmission portion formed on a proximal side that is a proximal end side of the insertion tube.

The in-vivo treatment device according to claim 1, wherein an opening area of the capturing portion is smaller than an opening area of the transmitting portion.

[4] The in-vivo treatment device according to [3], wherein the opening of the transmission portion extends along the longitudinal direction of the insertion tube.

[5] comprising a wire that is movably inserted into the insertion tube,

5. The living tube according to claim 1, wherein the wire passes through the filter portion and is coupled to a distal side portion which is a distal end side of the insertion tube. Treatment tool.

[6] An in-vivo treatment device that captures and removes foreign matter in a living body tube by a filter portion protruding in the outer diameter direction,

An insertion tube made of a shape memory alloy that is inserted into the living body tube, and a wire that is inserted into the insertion tube so as to move.

In the insertion tube, at least one place along the axial direction of the insertion tube forms the filter part, The filter part is cut into a spiral shape along the axial direction of the insertion tube on the peripheral surface of the insertion tube to form a cutting part, and the filter component formed between the cutting parts is disposed outside the insertion pipe. The shape is memorized and formed in the expanded state in the radial direction,

The in-vivo treatment device according to claim 1, wherein the wire passes through the filter portion and is joined to a distal side portion which is a distal end side of the insertion tube.

The in-vivo treatment device according to claim 5 or 6, wherein one end of the wire protrudes from a proximal end that is a proximal end side of the insertion tube.