WO2006090389A3 - Novel diagnostic markers, especially for in vivo imaging, and assays and methods of use thereof - Google Patents
Novel diagnostic markers, especially for in vivo imaging, and assays and methods of use thereof Download PDFInfo
- Publication number
- WO2006090389A3 WO2006090389A3 PCT/IL2006/000251 IL2006000251W WO2006090389A3 WO 2006090389 A3 WO2006090389 A3 WO 2006090389A3 IL 2006000251 W IL2006000251 W IL 2006000251W WO 2006090389 A3 WO2006090389 A3 WO 2006090389A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- assays
- methods
- diagnostic markers
- vivo imaging
- novel diagnostic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21109—Matriptase (3.4.21.109)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
Abstract
Novel splice variants as diagnostic markers, preferably membrane-bound. The novel variants according to the present invention may optionally be used for diagnosis of Marker-detectable disease as described herein, optionally through immunohistochemistry.
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP06711233A EP1851543A2 (en) | 2005-02-24 | 2006-02-23 | Novel diagnostic markers, especially for in vivo imaging, and assays and methods of use thereof |
IL185501A IL185501A0 (en) | 2005-02-24 | 2007-08-23 | Novel diagnostic markers, especially for in vivo imaging, and assays and methods of use thereof |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IL16709105 | 2005-02-24 | ||
IL167091 | 2005-02-24 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2006090389A2 WO2006090389A2 (en) | 2006-08-31 |
WO2006090389A3 true WO2006090389A3 (en) | 2007-11-29 |
Family
ID=36778256
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/IL2006/000251 WO2006090389A2 (en) | 2005-02-24 | 2006-02-23 | Novel diagnostic markers, especially for in vivo imaging, and assays and methods of use thereof |
Country Status (4)
Country | Link |
---|---|
US (3) | US7488813B2 (en) |
EP (1) | EP1851543A2 (en) |
IL (1) | IL185501A0 (en) |
WO (1) | WO2006090389A2 (en) |
Families Citing this family (21)
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EP2385143B1 (en) | 2006-02-02 | 2016-07-13 | The Board of Trustees of the Leland Stanford Junior University | Non-invasive fetal genetic screening by digital analysis |
DK2117571T3 (en) * | 2006-12-08 | 2017-05-08 | Monopar Therapeutics Inc | Urokinase-type plasminogen activator receptor epitope |
ES2430290T3 (en) * | 2007-03-06 | 2013-11-19 | F. Hoffmann-La Roche Ag | Use of PNC type peptides to predict the need for dialysis |
WO2008154225A2 (en) * | 2007-06-06 | 2008-12-18 | Bayer Healthcare Llc | Microdeposition system for a biosensor |
DK2185933T3 (en) * | 2007-08-07 | 2015-10-26 | Oxford Biotherapeutics Ltd | MATRIPTASE PROTEIN AND APPLICATIONS THEREOF |
US11307201B2 (en) * | 2007-09-17 | 2022-04-19 | Red Ivory Llc | Self-actuating signal producing detection devices and methods |
AU2008364786B2 (en) * | 2008-12-05 | 2014-04-03 | The Government Of The U.S.A., As Represented By The Secretary, Department Of Health & Human Services | Blocking mesothelin peptide fragments |
CA2740806C (en) | 2008-12-09 | 2021-07-20 | Bryan Irving | Anti-pd-l1 antibodies and their use to enhance t-cell function |
US8348856B1 (en) | 2008-12-16 | 2013-01-08 | Zanetta Malanowska-Stega | Simultaneous multiple method out-patient uterus biopsy device and method |
DE102010002316B4 (en) * | 2010-02-24 | 2011-12-08 | Bruker Biospin Gmbh | Analysis system with coupling of GPC and NMR spectroscopy, in particular for the analysis of polymer-containing test samples |
US9536162B2 (en) * | 2011-01-17 | 2017-01-03 | Republic of Korea (National Forensic Service Director Ministry of Public Administration and Security) | Method for detecting an invisible mark on a card |
CN103826662A (en) * | 2011-07-06 | 2014-05-28 | 美艾利尔圣地亚哥公司 | Methods and compositions for assigning likelihood of acute kidney injury progression |
US20140279712A1 (en) * | 2013-03-15 | 2014-09-18 | American Metering Services, Inc. | Utility monitoring and billing systems, and methods |
AR098523A1 (en) | 2013-11-25 | 2016-06-01 | Oxford Biotherapeutics Ltd | DIRECTED ANTIBODIES AGAINST MATRIPTASE AND RELATED COMPOSITIONS |
WO2015085398A1 (en) * | 2013-12-09 | 2015-06-18 | British Columbia Cancer Agency Branch | Matriptase variants associated with tumors |
CN110248609A (en) | 2016-12-09 | 2019-09-17 | 扎内塔·马拉诺夫斯卡-斯蒂加 | Brush biopsy device, tool set and method |
CN107091730A (en) * | 2017-06-08 | 2017-08-25 | 金华职业技术学院 | Estimate the device of absolute light responsiveness of the photomultiplier under low light-intensity conditions |
AU2018290281B2 (en) | 2017-06-22 | 2021-12-16 | Vertex Pharmaceuticals Incorporated | Modified membrane type serine protease 1 (MTSP-1) polypeptides and methods of use |
US11685951B2 (en) | 2017-07-18 | 2023-06-27 | The Research Foundation For The State University Of New York | Biomarkers for intracranial aneurysm |
CN112679617B (en) * | 2021-01-15 | 2021-09-17 | 北京鼎成肽源生物技术有限公司 | Mammal fusion protein display plasmid based on mesothelin anchoring, cell line and application |
AU2022222688A1 (en) * | 2021-02-16 | 2023-07-06 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Molecules that bind to mesothelin polypeptides |
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-
2006
- 2006-02-23 WO PCT/IL2006/000251 patent/WO2006090389A2/en active Application Filing
- 2006-02-23 EP EP06711233A patent/EP1851543A2/en not_active Withdrawn
- 2006-02-24 US US11/362,260 patent/US7488813B2/en not_active Expired - Fee Related
-
2007
- 2007-08-23 IL IL185501A patent/IL185501A0/en unknown
- 2007-10-30 US US11/929,570 patent/US7741433B2/en not_active Expired - Fee Related
-
2010
- 2010-04-12 US US12/758,521 patent/US20100189652A1/en not_active Abandoned
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1999042120A1 (en) * | 1998-02-20 | 1999-08-26 | The Board Of Trustees Of The University Of Arkansas | Tadg-15: an extracellular serine protease overexpressed in breast and ovarian carcinomas |
WO2001023524A2 (en) * | 1999-09-30 | 2001-04-05 | The Regents Of The University Of California | Membrane type serine protease 1 (mt-sp1) and uses thereof |
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Non-Patent Citations (1)
Title |
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GE WEITING ET AL: "PROTEIN INTERACTION ANALYSIS OF ST14 DOMAINS AND THEIR POINT AND DELETION MUTANTS", JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY OF BIOLOCHEMICAL BIOLOGISTS, BIRMINGHAM,, US, vol. 281, no. 11, March 2006 (2006-03-01), pages 7406 - 7412, XP009078647, ISSN: 0021-9258 * |
Also Published As
Publication number | Publication date |
---|---|
US20100189652A1 (en) | 2010-07-29 |
EP1851543A2 (en) | 2007-11-07 |
IL185501A0 (en) | 2008-01-20 |
WO2006090389A2 (en) | 2006-08-31 |
US20060257896A1 (en) | 2006-11-16 |
US7741433B2 (en) | 2010-06-22 |
US20090202991A1 (en) | 2009-08-13 |
US7488813B2 (en) | 2009-02-10 |
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