WO2006110859A3 - Method for data reduction and calibration of an oct-based blood glucose monitor - Google Patents

Method for data reduction and calibration of an oct-based blood glucose monitor Download PDF

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Publication number
WO2006110859A3
WO2006110859A3 PCT/US2006/013775 US2006013775W WO2006110859A3 WO 2006110859 A3 WO2006110859 A3 WO 2006110859A3 US 2006013775 W US2006013775 W US 2006013775W WO 2006110859 A3 WO2006110859 A3 WO 2006110859A3
Authority
WO
WIPO (PCT)
Prior art keywords
blood glucose
oct
glucose monitor
calibration
data
Prior art date
Application number
PCT/US2006/013775
Other languages
French (fr)
Other versions
WO2006110859A2 (en
Inventor
Matthew J Schurman
Walter J Shakespeare
William Henry Bennett
Original Assignee
Glucolight Corp
Matthew J Schurman
Walter J Shakespeare
William Henry Bennett
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glucolight Corp, Matthew J Schurman, Walter J Shakespeare, William Henry Bennett filed Critical Glucolight Corp
Priority to AU2006235535A priority Critical patent/AU2006235535A1/en
Priority to EP06749973A priority patent/EP1874178A4/en
Priority to JP2008506669A priority patent/JP2008537903A/en
Priority to CA002604653A priority patent/CA2604653A1/en
Publication of WO2006110859A2 publication Critical patent/WO2006110859A2/en
Publication of WO2006110859A3 publication Critical patent/WO2006110859A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0062—Arrangements for scanning
    • A61B5/0066—Optical coherence imaging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/153—Devices specially adapted for taking samples of venous or arterial blood, e.g. with syringes
    • A61B5/154—Devices using pre-evacuated means
    • A61B5/1545—Devices using pre-evacuated means comprising means for indicating vein or arterial entry
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/44—Detecting, measuring or recording for evaluating the integumentary system, e.g. skin, hair or nails
    • A61B5/441—Skin evaluation, e.g. for skin disorder diagnosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7235—Details of waveform analysis
    • A61B5/7246—Details of waveform analysis using correlation, e.g. template matching or determination of similarity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7271—Specific aspects of physiological measurement analysis
    • A61B5/7278—Artificial waveform generation or derivation, e.g. synthesising signals from measured signals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2560/00—Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
    • A61B2560/02—Operational features
    • A61B2560/0223—Operational features of calibration, e.g. protocols for calibrating sensors

Abstract

The present invention relates to a method for estimating blood glucose levels using a noninvasive optical coherence tomography-(OCT-) based blood glucose monitor. An algorithm correlates OCT-based estimated blood glucose data with actual blood glucose data determined by invasive methods. OCT-based data is fit to the obtained blood glucose measurements to achieve the best correlation. Once the algorithm has generated sets of estimated blood glucose levels, it may refine the number of sets by applying one or more mathematical filters. The OCT-based blood glucose monitor is calibrated using an Intensity Difference plot or the Pearson Product Moment Correlation method.
PCT/US2006/013775 2005-04-13 2006-04-13 Method for data reduction and calibration of an oct-based blood glucose monitor WO2006110859A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
AU2006235535A AU2006235535A1 (en) 2005-04-13 2006-04-13 Method for data reduction and calibration of an OCT-based blood glucose monitor
EP06749973A EP1874178A4 (en) 2005-04-13 2006-04-13 Method for data reduction and calibration of an oct-based blood glucose monitor
JP2008506669A JP2008537903A (en) 2005-04-13 2006-04-13 Data processing and calibration method for blood glucose monitor based on OCT
CA002604653A CA2604653A1 (en) 2005-04-13 2006-04-13 Method for data reduction and calibration of an oct-based blood glucose monitor

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US67100705P 2005-04-13 2005-04-13
US60/671,007 2005-04-13
US67128505P 2005-04-14 2005-04-14
US60/671,285 2005-04-14

Publications (2)

Publication Number Publication Date
WO2006110859A2 WO2006110859A2 (en) 2006-10-19
WO2006110859A3 true WO2006110859A3 (en) 2006-12-14

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/013775 WO2006110859A2 (en) 2005-04-13 2006-04-13 Method for data reduction and calibration of an oct-based blood glucose monitor

Country Status (6)

Country Link
US (7) US7822452B2 (en)
EP (1) EP1874178A4 (en)
JP (1) JP2008537903A (en)
AU (1) AU2006235535A1 (en)
CA (1) CA2604653A1 (en)
WO (1) WO2006110859A2 (en)

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