WO2007028135A3 - Imidazopyridine compounds - Google Patents

Imidazopyridine compounds Download PDF

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Publication number
WO2007028135A3
WO2007028135A3 PCT/US2006/034441 US2006034441W WO2007028135A3 WO 2007028135 A3 WO2007028135 A3 WO 2007028135A3 US 2006034441 W US2006034441 W US 2006034441W WO 2007028135 A3 WO2007028135 A3 WO 2007028135A3
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WO
WIPO (PCT)
Prior art keywords
imidazopyridine compounds
compounds
imidazopyridine
glucokinase
kits
Prior art date
Application number
PCT/US2006/034441
Other languages
French (fr)
Other versions
WO2007028135A2 (en
Inventor
Hidehisa Iwata
Yasuhisa Kohara
Sheldon X Cao
Prasuna Guntupalli
Stephen L Gwaltney
David J Hosfield
Yan Liu
Jeffrey A Stafford
Beverly Throop
Original Assignee
Takeda Pharmaceutical
Takeda San Diego Inc
Hidehisa Iwata
Yasuhisa Kohara
Sheldon X Cao
Prasuna Guntupalli
Stephen L Gwaltney
David J Hosfield
Yan Liu
Jeffrey A Stafford
Beverly Throop
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Pharmaceutical, Takeda San Diego Inc, Hidehisa Iwata, Yasuhisa Kohara, Sheldon X Cao, Prasuna Guntupalli, Stephen L Gwaltney, David J Hosfield, Yan Liu, Jeffrey A Stafford, Beverly Throop filed Critical Takeda Pharmaceutical
Priority to US12/065,607 priority Critical patent/US8124617B2/en
Priority to JP2008529362A priority patent/JP2009507039A/en
Priority to EP06802913A priority patent/EP1940837B1/en
Publication of WO2007028135A2 publication Critical patent/WO2007028135A2/en
Publication of WO2007028135A3 publication Critical patent/WO2007028135A3/en

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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
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    • C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/01—Phosphotransferases with an alcohol group as acceptor (2.7.1)
    • C12Y207/01001—Hexokinase (2.7.1.1)

Abstract

Compounds, pharmaceutical compositions, kits and methods are provided for use with glucokinase that comprise a compound selected from the group consisting of formula (I) wherein the variables are as defined herein.
PCT/US2006/034441 2005-09-01 2006-09-01 Imidazopyridine compounds WO2007028135A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
US12/065,607 US8124617B2 (en) 2005-09-01 2006-09-01 Imidazopyridine compounds
JP2008529362A JP2009507039A (en) 2005-09-01 2006-09-01 Imidazopyridine compounds
EP06802913A EP1940837B1 (en) 2005-09-01 2006-09-01 Imidazopyridine compounds

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2005-254194U 2005-09-01
JP2005254194A JP2007063225A (en) 2005-09-01 2005-09-01 Imidazopyridine compound

Publications (2)

Publication Number Publication Date
WO2007028135A2 WO2007028135A2 (en) 2007-03-08
WO2007028135A3 true WO2007028135A3 (en) 2007-11-01

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PCT/US2006/034441 WO2007028135A2 (en) 2005-09-01 2006-09-01 Imidazopyridine compounds

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US (1) US8124617B2 (en)
EP (1) EP1940837B1 (en)
JP (2) JP2007063225A (en)
WO (1) WO2007028135A2 (en)

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JPWO2008136428A1 (en) 2007-04-27 2010-07-29 武田薬品工業株式会社 Nitrogen-containing 5-membered heterocyclic compound
WO2009022179A2 (en) * 2007-08-14 2009-02-19 Astrazeneca Ab Glucokinase activators in the treatment of osteoarthritis
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JPWO2010076884A1 (en) 2008-12-29 2012-06-21 武田薬品工業株式会社 Novel fused ring compounds and uses thereof
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