WO2007030367A3 - Method for treating subcutaneous tissues - Google Patents

Method for treating subcutaneous tissues Download PDF

Info

Publication number
WO2007030367A3
WO2007030367A3 PCT/US2006/033855 US2006033855W WO2007030367A3 WO 2007030367 A3 WO2007030367 A3 WO 2007030367A3 US 2006033855 W US2006033855 W US 2006033855W WO 2007030367 A3 WO2007030367 A3 WO 2007030367A3
Authority
WO
WIPO (PCT)
Prior art keywords
subcutaneous
subcutaneous tissues
enhancing agents
treating subcutaneous
ultrasound waves
Prior art date
Application number
PCT/US2006/033855
Other languages
French (fr)
Other versions
WO2007030367A2 (en
Inventor
Mark E Deem
Hanson S Gifford Iii
Douglas Sutton
Original Assignee
The Foundry Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Foundry Inc filed Critical The Foundry Inc
Priority to CA002621354A priority Critical patent/CA2621354A1/en
Priority to EP06802625A priority patent/EP1940300A4/en
Priority to AU2006287678A priority patent/AU2006287678A1/en
Priority to JP2008530099A priority patent/JP2009506870A/en
Publication of WO2007030367A2 publication Critical patent/WO2007030367A2/en
Publication of WO2007030367A3 publication Critical patent/WO2007030367A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00—Ultrasound therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0028—Disruption, e.g. by heat or ultrasounds, sonophysical or sonochemical activation, e.g. thermosensitive or heat-sensitive liposomes, disruption of calculi with a medicinal preparation and ultrasounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0092—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin using ultrasonic, sonic or infrasonic vibrations, e.g. phonophoresis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0412—Specially adapted for transcutaneous electroporation, e.g. including drug reservoirs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0472—Structure-related aspects
    • A61N1/0492—Patch electrodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00743—Type of operation; Specification of treatment sites
    • A61B2017/00747—Dermatology
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A61B17/22004—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for using mechanical vibrations, e.g. ultrasonic shock waves
    • A61B2017/22005—Effects, e.g. on tissue
    • A61B2017/22007—Cavitation or pseudocavitation, i.e. creation of gas bubbles generating a secondary shock wave when collapsing
    • A61B2017/22008—Cavitation or pseudocavitation, i.e. creation of gas bubbles generating a secondary shock wave when collapsing used or promoted
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0009—Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/003—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles having a lumen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/327—Applying electric currents by contact electrodes alternating or intermittent currents for enhancing the absorption properties of tissue, e.g. by electroporation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00—Ultrasound therapy
    • A61N2007/0004—Applications of ultrasound therapy
    • A61N2007/0008—Destruction of fat cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00—Ultrasound therapy
    • A61N2007/0039—Ultrasound therapy using microbubbles

Abstract

An apparatus and method for treating subcutaneous tissues using acoustic waves in the range of low acoustic pressure ultrasound waves is disclosed. The method includes injections of enhancing agents, wherein disruption of subcutaneous tissues and subcutaneous cavitational bioeffects are produced by ultrasound waves having a power that will not produce tissue cavitation in the absence of the enhancing agents. The apparatus and method of use is useful for treatment of subcutaneous abnormalities including cellulite, lipomas, and tumors.
PCT/US2006/033855 2005-09-07 2006-08-30 Method for treating subcutaneous tissues WO2007030367A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
CA002621354A CA2621354A1 (en) 2005-09-07 2006-08-30 Method for treating subcutaneous tissues
EP06802625A EP1940300A4 (en) 2005-09-07 2006-08-30 Method for treating subcutaneous tissues
AU2006287678A AU2006287678A1 (en) 2005-09-07 2006-08-30 Method for treating subcutaneous tissues
JP2008530099A JP2009506870A (en) 2005-09-07 2006-08-30 How to treat subcutaneous tissue

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US71539805P 2005-09-07 2005-09-07
US60/715,398 2005-09-07
US11/292,950 US7967763B2 (en) 2005-09-07 2005-12-02 Method for treating subcutaneous tissues
US11/292,950 2005-12-02

Publications (2)

Publication Number Publication Date
WO2007030367A2 WO2007030367A2 (en) 2007-03-15
WO2007030367A3 true WO2007030367A3 (en) 2007-06-21

Family

ID=37830884

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/033855 WO2007030367A2 (en) 2005-09-07 2006-08-30 Method for treating subcutaneous tissues

Country Status (6)

Country Link
US (6) US7967763B2 (en)
EP (1) EP1940300A4 (en)
JP (1) JP2009506870A (en)
AU (1) AU2006287678A1 (en)
CA (1) CA2621354A1 (en)
WO (1) WO2007030367A2 (en)

Families Citing this family (234)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6104959A (en) 1997-07-31 2000-08-15 Microwave Medical Corp. Method and apparatus for treating subcutaneous histological features
JP2005535370A (en) 2002-06-19 2005-11-24 パロマー・メディカル・テクノロジーズ・インコーポレイテッド Method and apparatus for treating skin and subcutaneous conditions
JP4373699B2 (en) * 2003-04-28 2009-11-25 株式会社東芝 Ultrasonic diagnostic equipment
US8571648B2 (en) 2004-05-07 2013-10-29 Aesthera Apparatus and method to apply substances to tissue
WO2006044997A2 (en) * 2004-10-15 2006-04-27 The Trustees Of Columbia University In The City Of New York System and method for localized measurement and imaging of viscosity of tissues
WO2006044996A2 (en) * 2004-10-15 2006-04-27 The Trustees Of Columbia University In The City Of New York System and method for automated boundary detection of body structures
US7856985B2 (en) 2005-04-22 2010-12-28 Cynosure, Inc. Method of treatment body tissue using a non-uniform laser beam
US10687785B2 (en) 2005-05-12 2020-06-23 The Trustees Of Columbia Univeristy In The City Of New York System and method for electromechanical activation of arrhythmias
US20070016039A1 (en) * 2005-06-21 2007-01-18 Insightec-Image Guided Treatment Ltd. Controlled, non-linear focused ultrasound treatment
US7967763B2 (en) 2005-09-07 2011-06-28 Cabochon Aesthetics, Inc. Method for treating subcutaneous tissues
US10548659B2 (en) 2006-01-17 2020-02-04 Ulthera, Inc. High pressure pre-burst for improved fluid delivery
US9011473B2 (en) 2005-09-07 2015-04-21 Ulthera, Inc. Dissection handpiece and method for reducing the appearance of cellulite
US9486274B2 (en) 2005-09-07 2016-11-08 Ulthera, Inc. Dissection handpiece and method for reducing the appearance of cellulite
US8518069B2 (en) 2005-09-07 2013-08-27 Cabochon Aesthetics, Inc. Dissection handpiece and method for reducing the appearance of cellulite
US9358033B2 (en) * 2005-09-07 2016-06-07 Ulthera, Inc. Fluid-jet dissection system and method for reducing the appearance of cellulite
EP1937151A4 (en) * 2005-09-19 2011-07-06 Univ Columbia Systems and methods for opening of the blood-brain barrier of a subject using ultrasound
US10219815B2 (en) 2005-09-22 2019-03-05 The Regents Of The University Of Michigan Histotripsy for thrombolysis
US20070078290A1 (en) * 2005-09-30 2007-04-05 Esenaliev Rinat O Ultrasound-based treatment methods for therapeutic treatment of skin and subcutaneous tissues
US20080200864A1 (en) * 2005-12-02 2008-08-21 Cabochon Aesthetics, Inc. Devices and methods for selectively lysing cells
US20080200863A1 (en) * 2005-12-02 2008-08-21 Cabochon Aesthetics, Inc. Devices and methods for selectively lysing cells
US9248317B2 (en) 2005-12-02 2016-02-02 Ulthera, Inc. Devices and methods for selectively lysing cells
US20080014627A1 (en) * 2005-12-02 2008-01-17 Cabochon Aesthetics, Inc. Devices and methods for selectively lysing cells
US7885793B2 (en) * 2007-05-22 2011-02-08 International Business Machines Corporation Method and system for developing a conceptual model to facilitate generating a business-aligned information technology solution
US20080195036A1 (en) * 2005-12-02 2008-08-14 Cabochon Aesthetics, Inc. Devices and methods for selectively lysing cells
US8133191B2 (en) * 2006-02-16 2012-03-13 Syneron Medical Ltd. Method and apparatus for treatment of adipose tissue
US20070213705A1 (en) * 2006-03-08 2007-09-13 Schmid Peter M Insulated needle and system
US20070299539A1 (en) * 2006-04-12 2007-12-27 Shadi Othman Ultrasound accelerated tissue engineering process
US8235901B2 (en) * 2006-04-26 2012-08-07 Insightec, Ltd. Focused ultrasound system with far field tail suppression
CA2654316C (en) * 2006-06-07 2015-04-07 Trinity Wound Institute, Llc Oxygen therapy with ultrasound
US7586957B2 (en) 2006-08-02 2009-09-08 Cynosure, Inc Picosecond laser apparatus and methods for its operation and use
US8150128B2 (en) * 2006-08-30 2012-04-03 The Trustees Of Columbia University In The City Of New York Systems and method for composite elastography and wave imaging
US9132031B2 (en) 2006-09-26 2015-09-15 Zeltiq Aesthetics, Inc. Cooling device having a plurality of controllable cooling elements to provide a predetermined cooling profile
US20080077201A1 (en) * 2006-09-26 2008-03-27 Juniper Medical, Inc. Cooling devices with flexible sensors
US8192474B2 (en) 2006-09-26 2012-06-05 Zeltiq Aesthetics, Inc. Tissue treatment methods
US20100041989A1 (en) * 2006-09-29 2010-02-18 The Trustees Of The University Of Pennsylvania Use of ultrasound as an antivascular agent
WO2008074005A1 (en) * 2006-12-13 2008-06-19 Palomar Medical Technologies, Inc. Cosmetic and biomedical applications of ultrasonic energy and methods of generation thereof
US20080154180A1 (en) * 2006-12-15 2008-06-26 Walter Ray Seidel Ultra-Lipodissolve Method
WO2009128940A1 (en) 2008-04-17 2009-10-22 Miramar Labs, Inc. Systems, apparatus, methods and procedures for the noninvasive treatment of tissue using microwave energy
JP2010524591A (en) 2007-04-19 2010-07-22 ザ ファウンドリー， インコーポレイテッド Method and apparatus for reducing sweat production
EP2767308B1 (en) 2007-04-19 2016-04-13 Miramar Labs, Inc. Devices, and systems for non-invasive delivery of microwave therapy
CN101711134B (en) 2007-04-19 2016-08-17 米勒玛尔实验室公司 Tissue is applied the system of microwave energy and in organized layer, produces the system of tissue effect
WO2008131306A1 (en) 2007-04-19 2008-10-30 The Foundry, Inc. Systems and methods for creating an effect using microwave energy to specified tissue
JP6100613B2 (en) * 2007-04-19 2017-03-22 ミラマー ラブズ， インコーポレイテッド Method and apparatus for reducing sweat production
GB2460386B (en) * 2007-05-03 2012-01-11 Vibrant Medical Ltd Vibration pad cover
US20150174388A1 (en) 2007-05-07 2015-06-25 Guided Therapy Systems, Llc Methods and Systems for Ultrasound Assisted Delivery of a Medicant to Tissue
WO2008141221A1 (en) * 2007-05-09 2008-11-20 Old Dominion University Research Foundation Suction electrode-based medical instrument and system including the medical instrument for therapeutic electrotherapy
US20080287839A1 (en) 2007-05-18 2008-11-20 Juniper Medical, Inc. Method of enhanced removal of heat from subcutaneous lipid-rich cells and treatment apparatus having an actuator
US20080294072A1 (en) * 2007-05-24 2008-11-27 Crutchfield Dermatology Mesotherapy with ultrasound
US20090012434A1 (en) * 2007-07-03 2009-01-08 Anderson Robert S Apparatus, method, and system to treat a volume of skin
US8523927B2 (en) 2007-07-13 2013-09-03 Zeltiq Aesthetics, Inc. System for treating lipid-rich regions
US9909098B2 (en) * 2007-08-06 2018-03-06 The Regents Of The University Of California Methods of tissue-based diagnosis
US8609041B2 (en) 2007-08-06 2013-12-17 Samir Mitragotri Apparatus for solubilizing tissue
US9814422B2 (en) 2007-08-06 2017-11-14 The Regents Of The University Of California Compositions for solubilizing cells and/or tissue
US8642664B2 (en) 2007-08-06 2014-02-04 Samir Mitragotri Composition for solubilizing tissue and cells comprising N-tetradecyl-N,N-dimethyl-3-ammonio-1-propanesulfonate and polyoxyethylene (10) cetyl ether
US8389582B2 (en) 2007-08-06 2013-03-05 Samir Mitragotri Composition for solubilizing tissue comprising 3-(decyl dimethyl ammonio) propane sulfonate and tetraethylene glycol dodecyl ether
CN103083794B (en) 2007-08-14 2016-03-02 弗雷德哈钦森癌症研究中心 For needle array assembly and the method for delivering therapeutic agents
ES2693430T3 (en) 2007-08-21 2018-12-11 Zeltiq Aesthetics, Inc. Monitoring of cooling of lipid-rich subcutaneous cells, such as cooling of adipose tissue
US20090069795A1 (en) * 2007-09-10 2009-03-12 Anderson Robert S Apparatus and method for selective treatment of tissue
US20090093723A1 (en) * 2007-10-05 2009-04-09 Cabochon Aesthetics, Inc. Ultrasound device including dispenser
US20090093864A1 (en) * 2007-10-08 2009-04-09 Anderson Robert S Methods and devices for applying energy to tissue
US8439940B2 (en) 2010-12-22 2013-05-14 Cabochon Aesthetics, Inc. Dissection handpiece with aspiration means for reducing the appearance of cellulite
US20090093738A1 (en) * 2007-10-09 2009-04-09 Cabochon Aesthetics, Inc. Device and method for monitoring a treatment area
EP2209424A1 (en) * 2007-10-09 2010-07-28 Cabochon Aesthetics, Inc. Ultrasound apparatus with treatment lens
JP4388115B2 (en) * 2007-10-15 2009-12-24 田 邦 彦 満 Ozone treatment device for acne disease
US20090157152A1 (en) * 2007-10-19 2009-06-18 Shiseido Company, Ltd. Cosmetic method for improving skin condition of face and neck, and apparatus thereof
KR101826243B1 (en) 2007-12-12 2018-02-06 미라마 랩스 인코포레이티드 Systems, apparatus, methods and procedures for the noninvasive treatment of tissue using microwave energy
AU2008335715B2 (en) 2007-12-12 2014-01-23 Miradry, Inc. Systems, apparatus, methods and procedures for the noninvasive treatment of tissue using microwave energy
US20090171266A1 (en) * 2008-01-01 2009-07-02 Dagan Harris Combination therapy
WO2011035312A1 (en) * 2009-09-21 2011-03-24 The Trustees Of Culumbia University In The City Of New York Systems and methods for opening of a tissue barrier
US20090287205A1 (en) * 2008-05-16 2009-11-19 Boston Scientific Scimed, Inc. Systems and methods for preventing tissue popping caused by bubble expansion during tissue ablation
US20090312693A1 (en) * 2008-06-13 2009-12-17 Vytronus, Inc. System and method for delivering energy to tissue
US20100009424A1 (en) * 2008-07-14 2010-01-14 Natasha Forde Sonoporation systems and methods
US20100010484A1 (en) * 2008-07-14 2010-01-14 Primaeva Medical, Inc. Devices and methods for percutaneous energy delivery
WO2010014977A1 (en) * 2008-08-01 2010-02-04 The Trustees Of Columbia University In The City Of New York Systems and methods for matching and imaging tissue characteristics
US8512715B2 (en) * 2008-08-14 2013-08-20 The Cleveland Clinic Foundation Apparatus and method for treating a neuromuscular defect
WO2010030819A1 (en) 2008-09-10 2010-03-18 The Trustees Of Columbia University In The City Of New York Systems and methods for opening a tissue
US10980925B1 (en) 2008-10-14 2021-04-20 A Hoyos Llc High definition liposculpture
US9888933B1 (en) * 2008-10-14 2018-02-13 Alfredo Ernesto Hoyos Ariza Vaser assisted high definition liposculpture
US20100106063A1 (en) * 2008-10-29 2010-04-29 Cabochon Aesthetics, Inc. Ultrasound Enhancing Target for Treating Subcutaneous Tissue
US8603073B2 (en) 2008-12-17 2013-12-10 Zeltiq Aesthetics, Inc. Systems and methods with interrupt/resume capabilities for treating subcutaneous lipid-rich cells
US9375529B2 (en) 2009-09-02 2016-06-28 Becton, Dickinson And Company Extended use medical device
EP2396654B1 (en) 2009-02-13 2016-02-10 The Regents of The University of California Composition and method for tissue-based diagnosis
US8167280B2 (en) * 2009-03-23 2012-05-01 Cabochon Aesthetics, Inc. Bubble generator having disposable bubble cartridges
US8328795B2 (en) * 2009-04-03 2012-12-11 Candela Corporation Skin resurfacing at 1930 nm
US20100256596A1 (en) * 2009-04-07 2010-10-07 Cabochon Aesthetics, Inc. Fiber growth promoting implants for reducing the appearance of cellulite
US20120116221A1 (en) * 2009-04-09 2012-05-10 The Trustees Of The University Of Pennsylvania Methods and systems for image-guided treatment of blood vessels
US20120029397A1 (en) * 2009-04-15 2012-02-02 The University Of Virginia Tumor treatment using ultrasound cavitation
US8702774B2 (en) 2009-04-30 2014-04-22 Zeltiq Aesthetics, Inc. Device, system and method of removing heat from subcutaneous lipid-rich cells
WO2010127369A1 (en) * 2009-05-01 2010-11-04 Rational Biotechnology Inc. Eit (electrical impedance tomography) guided sonoporation, ultrasound tissue ablation and their use thereof
WO2010144545A1 (en) * 2009-06-09 2010-12-16 Vascular Technology, Inc. Soft tissue dissector
EP2459092B1 (en) * 2009-07-27 2019-09-18 Novoxel Ltd. Device for tissue vaporization
AU2010280361B2 (en) 2009-08-04 2015-10-08 Pollogen Ltd. Cosmetic skin rejuvination
WO2011017663A1 (en) 2009-08-07 2011-02-10 Cabochon Aesthetics, Inc. Dissection handpiece and method for reducing the appearance of cellulite
PL2461758T3 (en) 2009-08-07 2017-09-29 Ulthera, Inc. Dissection handpiece for reducing the appearance of cellulite
US11096708B2 (en) 2009-08-07 2021-08-24 Ulthera, Inc. Devices and methods for performing subcutaneous surgery
US9358064B2 (en) 2009-08-07 2016-06-07 Ulthera, Inc. Handpiece and methods for performing subcutaneous surgery
US8986211B2 (en) 2009-10-12 2015-03-24 Kona Medical, Inc. Energetic modulation of nerves
US8986231B2 (en) 2009-10-12 2015-03-24 Kona Medical, Inc. Energetic modulation of nerves
US8469904B2 (en) 2009-10-12 2013-06-25 Kona Medical, Inc. Energetic modulation of nerves
US9174065B2 (en) * 2009-10-12 2015-11-03 Kona Medical, Inc. Energetic modulation of nerves
US20110118600A1 (en) 2009-11-16 2011-05-19 Michael Gertner External Autonomic Modulation
US9119951B2 (en) 2009-10-12 2015-09-01 Kona Medical, Inc. Energetic modulation of nerves
US20110092880A1 (en) * 2009-10-12 2011-04-21 Michael Gertner Energetic modulation of nerves
US20160059044A1 (en) 2009-10-12 2016-03-03 Kona Medical, Inc. Energy delivery to intraparenchymal regions of the kidney to treat hypertension
US8295912B2 (en) 2009-10-12 2012-10-23 Kona Medical, Inc. Method and system to inhibit a function of a nerve traveling with an artery
US11590346B2 (en) 2009-11-16 2023-02-28 Pollogen Ltd. Apparatus and method for cosmetic treatment of human mucosal tissue
WO2011058565A2 (en) 2009-11-16 2011-05-19 Pollogen Ltd. Non-invasive fat removal
EP2525727A4 (en) 2010-01-19 2017-05-03 The Board of Regents of The University of Texas System Apparatuses and systems for generating high-frequency shockwaves, and methods of use
AU2011207506A1 (en) 2010-01-25 2012-08-09 Zeltiq Aesthetics, Inc. Home-use applicators for non-invasively removing heat from subcutaneous lipid-rich cells via phase change coolants, and associated devices, systems and methods
WO2011107927A1 (en) * 2010-03-01 2011-09-09 Yoni Iger Method and apparatus for the removal of non desired biological components from external surfaces of tissues
WO2011109735A2 (en) * 2010-03-05 2011-09-09 Cornell University Ultrasound-assisted convection enhanced delivery of compounds in vivo with a transducer cannula assembly
US8876740B2 (en) * 2010-04-12 2014-11-04 University Of Washington Methods and systems for non-invasive treatment of tissue using high intensity focused ultrasound therapy
EP4278986A3 (en) * 2010-05-07 2024-02-21 The General Hospital Corporation Method and apparatus for tissue grafting and copying
WO2011163264A2 (en) * 2010-06-21 2011-12-29 Candela Corporation Driving microneedle arrays into skin and delivering rf energy
US8192429B2 (en) 2010-06-29 2012-06-05 Theravant, Inc. Abnormality eradication through resonance
US9693728B2 (en) * 2010-06-29 2017-07-04 Lucidux, Llc Systems and methods for measuring mechanical properties of deformable materials
US8676338B2 (en) 2010-07-20 2014-03-18 Zeltiq Aesthetics, Inc. Combined modality treatment systems, methods and apparatus for body contouring applications
US20120046601A1 (en) * 2010-08-23 2012-02-23 Sing George L Methods for delivering novel cell and cell-based compositions
US9662458B2 (en) 2010-12-23 2017-05-30 Richard A. Schatz Injection needle insertion barrier
US20120165785A1 (en) * 2010-12-23 2012-06-28 Schatz Richard A Catheter System for a Needle Injector with an Automatic Needle/Barrier Extension
US9409006B2 (en) * 2011-04-10 2016-08-09 David Hirshberg Fat removal device and obesity treatment
WO2012162664A1 (en) 2011-05-26 2012-11-29 The Trustees Of Columbia University In The City Of New York Systems and methods for opening of a tissue barrier in primates
AR087170A1 (en) 2011-07-15 2014-02-26 Univ Texas APPARATUS FOR GENERATING THERAPEUTIC SHOCK WAVES AND ITS APPLICATIONS
US9314301B2 (en) 2011-08-01 2016-04-19 Miramar Labs, Inc. Applicator and tissue interface module for dermatological device
WO2013019830A2 (en) 2011-08-01 2013-02-07 Alcyone Lifesciences, Inc. Microfluidic drug delivery devices
CN103338815A (en) * 2011-08-01 2013-10-02 环爱心公司 Optical treatment device for scalp and hair
EP2771043A4 (en) 2011-10-28 2015-04-29 Presage Biosciences Inc Methods for drug delivery
WO2013136327A1 (en) * 2012-03-15 2013-09-19 Steadymed Ltd. Enhanced infusion-site pain-reduction for drug-delivery devices
KR102183581B1 (en) 2012-04-18 2020-11-27 싸이노슈어, 엘엘씨 Picosecond laser apparatus and methods for treating target tissues with same
JP6025828B2 (en) * 2012-05-01 2016-11-16 正典 佐伯 Antiperspirant device
US11318009B2 (en) 2012-05-04 2022-05-03 Lipocosm, Llc Surgical tools and methods for their use
WO2014055906A1 (en) 2012-10-05 2014-04-10 The Regents Of The University Of Michigan Bubble-induced color doppler feedback during histotripsy
WO2014059170A1 (en) 2012-10-10 2014-04-17 The Trustees Of Columbia University In The City Of New York Systems and methods for mechanical mapping of cardiac rhythm
EP2934627B1 (en) 2012-12-18 2021-04-07 Alcyone Lifesciences, Inc. Devices and methods for reducing or preventing backflow in a delivery system
RU2511068C1 (en) * 2013-02-18 2014-04-10 Федеральное государственное бюджетное учреждение "Дальневосточный научный центр физиологии и патологии дыхания" Сибирского отделения Российской академии медицинских наук (ФГБУ "ДНЦ ФПД" СО РАМН) Method of treating obesity
US10835767B2 (en) 2013-03-08 2020-11-17 Board Of Regents, The University Of Texas System Rapid pulse electrohydraulic (EH) shockwave generator apparatus and methods for medical and cosmetic treatments
US9545523B2 (en) 2013-03-14 2017-01-17 Zeltiq Aesthetics, Inc. Multi-modality treatment systems, methods and apparatus for altering subcutaneous lipid-rich tissue
US9072678B2 (en) 2013-03-14 2015-07-07 Pathak Holdings Llc Methods for local drug delivery by microinjection
US9844460B2 (en) 2013-03-14 2017-12-19 Zeltiq Aesthetics, Inc. Treatment systems with fluid mixing systems and fluid-cooled applicators and methods of using the same
US9789073B2 (en) 2013-03-14 2017-10-17 Pathak Holdings, Llc Compositions, methods and devices for local drug delivery
WO2014160387A2 (en) * 2013-03-14 2014-10-02 Pathak Holdings, Llc Compositions, methods and devices for local drug delivery
US10624865B2 (en) 2013-03-14 2020-04-21 Pathak Holdings Llc Methods, compositions, and devices for drug/live cell microarrays
EP3751684A1 (en) 2013-03-15 2020-12-16 Cynosure, Inc. Picosecond optical radiation systems and methods of use
JP2016514004A (en) * 2013-03-15 2016-05-19 プラム システムズ カンパニ Apparatus and method for tissue reactivation
WO2014153502A2 (en) * 2013-03-21 2014-09-25 Weinberg Medical Physics Llc Apparatus and method for spatially selective interventional neuroparticles
EP2994189A4 (en) * 2013-05-06 2017-01-18 Mupharma Pty Ltd Non-invasive agent applicator
US20140350518A1 (en) 2013-05-23 2014-11-27 Allergan, Inc. Syringe extrusion accessory
US20140350516A1 (en) 2013-05-23 2014-11-27 Allergan, Inc. Mechanical syringe accessory
US9247921B2 (en) 2013-06-07 2016-02-02 The Trustees Of Columbia University In The City Of New York Systems and methods of high frame rate streaming for treatment monitoring
US10456533B2 (en) 2013-06-17 2019-10-29 Alcyone Lifesciences, Inc. Methods and devices for protecting catheter tips and stereotactic fixtures for microcatheters
US11432900B2 (en) 2013-07-03 2022-09-06 Histosonics, Inc. Articulating arm limiter for cavitational ultrasound therapy system
US20160367015A1 (en) * 2013-07-03 2016-12-22 Aesthetic Medical Devices Device to optimize cosmetic injectable procedures
US10413359B2 (en) * 2013-07-18 2019-09-17 International Business Machines Corporation Laser-assisted transdermal delivery of nanoparticulates and hydrogels
WO2015013502A2 (en) 2013-07-24 2015-01-29 Miramar Labs, Inc. Apparatus and methods for the treatment of tissue using microwave energy
US10441770B2 (en) 2013-07-31 2019-10-15 Alcyone Lifesciences, Inc. Systems and methods for drug delivery, treatment, and monitoring
US10322178B2 (en) 2013-08-09 2019-06-18 The Trustees Of Columbia University In The City Of New York Systems and methods for targeted drug delivery
US10780298B2 (en) 2013-08-22 2020-09-22 The Regents Of The University Of Michigan Histotripsy using very short monopolar ultrasound pulses
US10117892B2 (en) 2013-08-29 2018-11-06 Allergan, Inc. Devices and methods for reducing the appearance of cellulite
US10028723B2 (en) 2013-09-03 2018-07-24 The Trustees Of Columbia University In The City Of New York Systems and methods for real-time, transcranial monitoring of blood-brain barrier opening
KR102329660B1 (en) 2013-12-18 2021-11-23 노보셀 리미티드 Devices and method for tissue vaporization
EP3099259A1 (en) 2014-01-31 2016-12-07 Zeltiq Aesthetics, Inc. Treatment systems and methods for affecting glands and other targeted structures
US10675176B1 (en) 2014-03-19 2020-06-09 Zeltiq Aesthetics, Inc. Treatment systems, devices, and methods for cooling targeted tissue
USD777338S1 (en) 2014-03-20 2017-01-24 Zeltiq Aesthetics, Inc. Cryotherapy applicator for cooling tissue
JP6579099B2 (en) * 2014-04-03 2019-09-25 凸版印刷株式会社 Puncture injection device
US10952891B1 (en) 2014-05-13 2021-03-23 Zeltiq Aesthetics, Inc. Treatment systems with adjustable gap applicators and methods for cooling tissue
US10029048B2 (en) 2014-05-13 2018-07-24 Allergan, Inc. High force injection devices
US10568759B2 (en) 2014-08-19 2020-02-25 Zeltiq Aesthetics, Inc. Treatment systems, small volume applicators, and methods for treating submental tissue
US10935174B2 (en) 2014-08-19 2021-03-02 Zeltiq Aesthetics, Inc. Stress relief couplings for cryotherapy apparatuses
CN106999237B (en) 2014-09-15 2020-06-12 诺服塞尔有限公司 Method and apparatus for thermal tissue vaporization and compression
US10226585B2 (en) 2014-10-01 2019-03-12 Allergan, Inc. Devices for injection and dosing
WO2016061587A1 (en) * 2014-10-17 2016-04-21 University Of Washington Broadly focused ultrasonic propulsion probes, systems, and methods
US10925579B2 (en) 2014-11-05 2021-02-23 Otsuka Medical Devices Co., Ltd. Systems and methods for real-time tracking of a target tissue using imaging before and during therapy delivery
WO2016112361A1 (en) * 2015-01-08 2016-07-14 University Of Washington Systems and methods for inhibiting heterotopic ossification
US10806396B2 (en) 2015-01-26 2020-10-20 Alcyone Lifesciences, Inc. Drug delivery methods with tracer
WO2016128976A1 (en) * 2015-02-10 2016-08-18 Shemi Daniela Efficient subcutaneous tissue treatment
WO2016141144A1 (en) * 2015-03-03 2016-09-09 Guided Therapy Systems, Llc Methods and systems for material transport across an impermeable or semi-permeable membrane via artificially created microchannels
CN107530490B (en) 2015-03-10 2021-06-25 爱力根销售有限责任公司 Multi-needle syringe
CN108290030B (en) * 2015-04-08 2022-07-12 麻省理工学院 System, apparatus and method for administering a substance
WO2016182861A1 (en) * 2015-05-08 2016-11-17 Kci Licensing, Inc. Wound debridement by irrigation with ultrasonically activated microbubbles
US11229575B2 (en) 2015-05-12 2022-01-25 Soliton, Inc. Methods of treating cellulite and subcutaneous adipose tissue
WO2016205335A1 (en) 2015-06-17 2016-12-22 Stryker European Holdings I, Llc Surgical instrument with ultrasonic tip for fibrous tissue removal
EP4230262A3 (en) 2015-06-24 2023-11-22 The Regents Of The University Of Michigan Histotripsy therapy systems for the treatment of brain tissue
US10188777B2 (en) * 2015-08-20 2019-01-29 Aurastem Llc Liposuction device and system and use thereof
ES2892598T3 (en) 2015-10-19 2022-02-04 Zeltiq Aesthetics Inc Vascular treatment methods to cool vascular structures
CN108472019A (en) 2016-01-04 2018-08-31 亚克安娜生命科学有限公司 Method and apparatus for treating apoplexy
KR102416368B1 (en) 2016-01-07 2022-07-04 젤티크 애스세틱스, 인코포레이티드. Temperature-dependent adhesion between the applicator and the skin during tissue cooling
US10765552B2 (en) 2016-02-18 2020-09-08 Zeltiq Aesthetics, Inc. Cooling cup applicators with contoured heads and liner assemblies
CN109152930A (en) * 2016-03-23 2019-01-04 索里顿有限责任公司 Pulsed sound skin clears up system and method
AU2017246114B2 (en) 2016-04-08 2022-03-17 Allergan, Inc. Aspiration and injection device
US10555831B2 (en) 2016-05-10 2020-02-11 Zeltiq Aesthetics, Inc. Hydrogel substances and methods of cryotherapy
US11382790B2 (en) 2016-05-10 2022-07-12 Zeltiq Aesthetics, Inc. Skin freezing systems for treating acne and skin conditions
US10682297B2 (en) 2016-05-10 2020-06-16 Zeltiq Aesthetics, Inc. Liposomes, emulsions, and methods for cryotherapy
WO2017212489A2 (en) 2016-06-06 2017-12-14 Archimedus Medical Ltd. Ultrasound transducer and system
TWI742110B (en) 2016-07-21 2021-10-11 美商席利通公司 Rapid pulse electrohydraulic (eh) shockwave generator apparatus with improved electrode lifetime and method of producing compressed acoustic wave using same
AU2017331263B2 (en) * 2016-09-23 2020-07-09 Inovio Pharmaceuticals, Inc. Method and device for minimally invasive in vivo transfection of adipose tissue using electroporation
EP3525883A4 (en) 2016-10-16 2020-12-02 Vibrato Medical, Inc. Extracorporeal therapeutic ultrasound for promoting angiogenesis
PT3534852T (en) 2016-11-02 2022-03-22 Miraki Innovation Think Tank Llc Devices and methods for slurry generation
US11324673B2 (en) 2016-11-18 2022-05-10 Miraki Innovation Think Tank Llc Cosmetic appearance of skin
BR112019017264A2 (en) 2017-02-19 2020-04-14 Soliton Inc selective laser-induced optical rupture in biological medium
USD867582S1 (en) 2017-03-24 2019-11-19 Allergan, Inc. Syringe device
WO2018187581A1 (en) 2017-04-05 2018-10-11 Arctic Fox Biomedical, Inc. Cold slurry containment
BR112019020971A8 (en) 2017-04-05 2022-11-16 Miraki Innovation Think Tank Llc DEVICE TO OBTAIN A COLD FLUID PASTE
US11076879B2 (en) 2017-04-26 2021-08-03 Zeltiq Aesthetics, Inc. Shallow surface cryotherapy applicators and related technology
CN110536648A (en) 2017-04-28 2019-12-03 奥拉斯泰姆有限责任公司 A kind of miniature fat suction needle instrument and its application method and production method
US10500342B2 (en) 2017-08-21 2019-12-10 Miraki Innovation Think Tank Llc Cold slurry syringe
CN111818953A (en) * 2018-01-07 2020-10-23 亚夫拉罕·阿米尔 High-load microneedles and compositions for skin improvement
WO2019165426A1 (en) 2018-02-26 2019-08-29 Cynosure, Inc. Q-switched cavity dumped sub-nanosecond laser
WO2019204639A1 (en) * 2018-04-18 2019-10-24 Vibrato Medical, Inc. Extracorporeal therapeutic ultrasound for promoting angiogenesis
MX2021000901A (en) 2018-07-23 2021-06-18 Revelle Aesthetics Inc Cellulite treatment system and methods.
BR112021001186A8 (en) 2018-07-23 2023-01-10 Nc8 Inc APPARATUS AND SYSTEM FOR THE TREATMENT OF CELLULITIS AND USE OF A SYSTEM FOR THE TREATMENT OF CELLULITIS FOR TREATMENT EXPRESSIONS OF CELLULITIS ON THE SKIN OF A PATIENT
CN112789013A (en) 2018-07-31 2021-05-11 斯尔替克美学股份有限公司 Method, device and system for improving skin
EP3829713A4 (en) * 2018-08-02 2022-05-11 Sofwave Medical Ltd. Fat tissue treatment
US11540894B2 (en) 2018-10-04 2023-01-03 Lipocosm, Llc Rigiditying brace
WO2020073021A1 (en) 2018-10-04 2020-04-09 Khouri Roger K Rigidifying brace
USD883767S1 (en) 2018-10-10 2020-05-12 A Hoyos Llc Handle
JP2022510654A (en) 2018-11-28 2022-01-27 ヒストソニックス，インコーポレーテッド Tissue disruption system and method
CN110042055B (en) * 2019-04-29 2022-05-13 新乡医学院 Operating table for cell ultrasound
KR102096204B1 (en) * 2019-05-31 2020-04-02 최명석 Localized fat destroying method and hypotonic solution for destroying localized fat
AU2021213168A1 (en) 2020-01-28 2022-09-01 The Regents Of The University Of Michigan Systems and methods for histotripsy immunosensitization
ES2793798B2 (en) * 2020-02-13 2022-04-29 Julia Jose Manuel Saenz ULTRASOUND EMITTING DEVICE FOR THE APPLICATION OF SELECTIVE TREATMENTS ON ADIPOSE TISSUE IN PROCESSES OF BODY REMODELING / REJUVENATION
IT202000013984A1 (en) * 2020-06-11 2021-12-11 Biotec Italia S R L DEVICE AND EQUIPMENT FOR SKIN REGENERATIVE TREATMENT AND LIPOLYSIS
KR20230035407A (en) 2020-07-10 2023-03-13 씨° 체인지 서지컬 엘엘씨 Injectable Slush Supply
FR3116450A1 (en) * 2020-11-26 2022-05-27 L'oreal Device for cleaning keratin materials generating gas bubbles
JP2023551826A (en) 2020-11-26 2023-12-13 ロレアル Method for cleansing human keratinous material, device and kit for carrying out said method
JP2024500330A (en) 2020-12-07 2024-01-09 リポコスム リミテッド ライアビリティ カンパニー External vacuum tissue dilator with non-adhesive rim
CN116803216A (en) 2020-12-31 2023-09-22 苏维夫医疗有限公司 Cooling of a plurality of ultrasonic exciters mounted on a plurality of printed circuit boards
US11717638B2 (en) 2021-02-09 2023-08-08 Thuy Doan Method for anesthetizing the lips
WO2022231011A1 (en) * 2021-04-28 2022-11-03 L'oreal Device for fluid injection therapy
FR3124397B1 (en) * 2021-06-24 2023-08-04 Oreal Device for fluid injection therapy
CN113520585B (en) * 2021-07-16 2022-06-17 河南科技大学第一附属医院 Isolation irrigation piece, ablation electrode tip and tumor radiofrequency ablation treatment device
WO2023222789A1 (en) 2022-05-18 2023-11-23 L'oreal Device for treating human keratin materials
FR3135604A1 (en) 2022-05-18 2023-11-24 L'oreal Device for treating human keratin materials
FR3135603A1 (en) 2022-05-18 2023-11-24 L'oreal Hair treatment device and method
FR3135605A1 (en) 2022-05-18 2023-11-24 L'oreal Process for cleaning human keratin materials

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5884631A (en) * 1997-04-17 1999-03-23 Silberg; Barry Body contouring technique and apparatus
US6375634B1 (en) * 1997-11-19 2002-04-23 Oncology Innovations, Inc. Apparatus and method to encapsulate, kill and remove malignancies, including selectively increasing absorption of x-rays and increasing free-radical damage to residual tumors targeted by ionizing and non-ionizing radiation therapy
US20020169394A1 (en) * 1993-11-15 2002-11-14 Eppstein Jonathan A. Integrated tissue poration, fluid harvesting and analysis device, and method therefor
US6500141B1 (en) * 1998-01-08 2002-12-31 Karl Storz Gmbh & Co. Kg Apparatus and method for treating body tissue, in particular soft surface tissue with ultrasound
US6685657B2 (en) * 1998-11-20 2004-02-03 Joie P. Jones Methods for selectively dissolving and removing materials using ultra-high frequency ultrasound
US6896659B2 (en) * 1998-02-06 2005-05-24 Point Biomedical Corporation Method for ultrasound triggered drug delivery using hollow microbubbles with controlled fragility
US6916328B2 (en) * 2001-11-15 2005-07-12 Expanding Concepts, L.L.C Percutaneous cellulite removal system

Family Cites Families (237)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US475921A (en) * 1892-05-31 Benny bernstein
US2370529A (en) 1942-04-21 1945-02-27 Fuller Katherine Golf ball teeing device
US2490409A (en) 1947-10-03 1949-12-06 Paul H Brown Golf practice target element
US2961382A (en) 1957-07-25 1960-11-22 Ortho Pharma Corp Urokinase-a plasmiogen activator and methods of obtaining the same
US3129944A (en) 1961-08-24 1964-04-21 Fuller Brush Co Golf mat composed of a plurality of parallel brush strips
GB1216813A (en) 1969-02-21 1970-12-23 Shozo Narusawa Transcutaneous injection device
CA1083040A (en) 1976-02-09 1980-08-05 Mostafa Fahim Topical application of medication by ultrasound with coupling agent
US4276885A (en) 1979-05-04 1981-07-07 Rasor Associates, Inc Ultrasonic image enhancement
US4657756A (en) 1980-11-17 1987-04-14 Schering Aktiengesellschaft Microbubble precursors and apparatus for their production and use
US4681119A (en) 1980-11-17 1987-07-21 Schering Aktiengesellschaft Method of production and use of microbubble precursors
DE3141641A1 (en) 1981-10-16 1983-04-28 Schering Ag, 1000 Berlin Und 4619 Bergkamen ULTRASONIC CONTRAST AGENTS AND THEIR PRODUCTION
US4718433A (en) 1983-01-27 1988-01-12 Feinstein Steven B Contrast agents for ultrasonic imaging
DE3313947A1 (en) 1983-04-15 1984-10-18 Schering AG, 1000 Berlin und 4709 Bergkamen MICROPARTICLES AND GAS BUBBLES CONTAINING ULTRASONIC CONTRASTING AGENTS
DE3313946A1 (en) 1983-04-15 1984-10-18 Schering AG, 1000 Berlin und 4709 Bergkamen MICROPARTICLES AND GAS BUBBLES CONTAINING ULTRASONIC CONTRASTING AGENTS
US4900540A (en) 1983-06-20 1990-02-13 Trustees Of The University Of Massachusetts Lipisomes containing gas for ultrasound detection
CH665127A5 (en) 1983-12-02 1988-04-29 Debiopharm Sa COUPLING PART FOR INJECTION SYRINGES.
US4549533A (en) 1984-01-30 1985-10-29 University Of Illinois Apparatus and method for generating and directing ultrasound
US4762915A (en) 1985-01-18 1988-08-09 Liposome Technology, Inc. Protein-liposome conjugates
US4689986A (en) 1985-03-13 1987-09-01 The University Of Michigan Variable frequency gas-bubble-manipulating apparatus and method
US4684479A (en) * 1985-08-14 1987-08-04 Arrigo Joseph S D Surfactant mixtures, stable gas-in-liquid emulsions, and methods for the production of such emulsions from said mixtures
US4751921A (en) 1985-10-21 1988-06-21 University Of Iowa Research Foundation Bone cement syringe
US4797285A (en) 1985-12-06 1989-01-10 Yissum Research And Development Company Of The Hebrew University Of Jerusalem Lipsome/anthraquinone drug composition and method
US4948587A (en) 1986-07-08 1990-08-14 Massachusetts Institute Of Technology Ultrasound enhancement of transbuccal drug delivery
US4720075A (en) 1986-07-28 1988-01-19 Buell Industries, Inc. Shock isolating mount
JPS63135179A (en) 1986-11-26 1988-06-07 立花　俊郎 Subcataneous drug administration set
US4815462A (en) 1987-04-06 1989-03-28 Clark Vickie J Lipectomy device
US5178433A (en) 1987-06-12 1993-01-12 Frank Wagner Vehicle body mount
US5040537A (en) 1987-11-24 1991-08-20 Hitachi, Ltd. Method and apparatus for the measurement and medical treatment using an ultrasonic wave
DE3741201A1 (en) 1987-12-02 1989-06-15 Schering Ag ULTRASONIC PROCESS AND METHOD FOR IMPLEMENTING IT
DE3741199A1 (en) 1987-12-02 1989-08-17 Schering Ag USE OF ULTRASONIC CONTRASTING AGENTS FOR ULTRASONIC LITHOTRIPSY
US4844882A (en) 1987-12-29 1989-07-04 Molecular Biosystems, Inc. Concentrated stabilized microbubble-type ultrasonic imaging agent
IE66912B1 (en) 1988-02-05 1996-02-07 Schering Ag Ultrasonic contrast agents process for their preparation and their use as diagnostic and therapeutic agents
US5143063A (en) 1988-02-09 1992-09-01 Fellner Donald G Method of removing adipose tissue from the body
US4886491A (en) 1988-02-29 1989-12-12 Tulio Parisi Liposuction procedure with ultrasonic probe
DE3812816A1 (en) 1988-04-16 1989-11-02 Lawaczeck Ruediger Dipl Phys P METHOD FOR SOLUBILIZING LIPOSOMES AND / OR BIOLOGICAL MEMBRANES AND THE USE THEREOF
US4844470A (en) 1988-06-06 1989-07-04 Ste-Mak, Inc. Golf mat
US5158071A (en) 1988-07-01 1992-10-27 Hitachi, Ltd. Ultrasonic apparatus for therapeutical use
US4920954A (en) 1988-08-05 1990-05-01 Sonic Needle Corporation Ultrasonic device for applying cavitation forces
US4957656A (en) 1988-09-14 1990-09-18 Molecular Biosystems, Inc. Continuous sonication method for preparing protein encapsulated microbubbles
DE3838530A1 (en) 1988-11-14 1990-05-17 Hilti Ag Packaging for two-component compounds
US5131600A (en) * 1989-02-13 1992-07-21 The Dow Chemical Company Alkanol amine grinding aids
FR2643252B1 (en) 1989-02-21 1991-06-07 Technomed Int Sa APPARATUS FOR THE SELECTIVE DESTRUCTION OF CELLS INCLUDING SOFT TISSUES AND BONES WITHIN THE BODY OF A LIVING BODY BY IMPLOSION OF GAS BUBBLES
US4936281A (en) 1989-04-13 1990-06-26 Everest Medical Corporation Ultrasonically enhanced RF ablation catheter
US5209720A (en) 1989-12-22 1993-05-11 Unger Evan C Methods for providing localized therapeutic heat to biological tissues and fluids using gas filled liposomes
US5733572A (en) 1989-12-22 1998-03-31 Imarx Pharmaceutical Corp. Gas and gaseous precursor filled microspheres as topical and subcutaneous delivery vehicles
US5149319A (en) 1990-09-11 1992-09-22 Unger Evan C Methods for providing localized therapeutic heat to biological tissues and fluids
US5088499A (en) 1989-12-22 1992-02-18 Unger Evan C Liposomes as contrast agents for ultrasonic imaging and methods for preparing the same
US5069664A (en) 1990-01-25 1991-12-03 Inter Therapy, Inc. Intravascular ultrasonic angioplasty probe
US5050537A (en) * 1990-05-01 1991-09-24 Fox Harvey Z Automatic animal feeding system
US5216130A (en) 1990-05-17 1993-06-01 Albany Medical College Complex for in-vivo target localization
US5215680A (en) * 1990-07-10 1993-06-01 Cavitation-Control Technology, Inc. Method for the production of medical-grade lipid-coated microbubbles, paramagnetic labeling of such microbubbles and therapeutic uses of microbubbles
WO1992009238A1 (en) 1990-11-30 1992-06-11 Michele Zocchi Method and apparatus for treating human fat tissue
US5425580A (en) 1990-12-28 1995-06-20 Byk Gulden Lomberg Chemische Fabrik Gmbh Dosage form for micro-bubble echo contrast agents
US5316000A (en) 1991-03-05 1994-05-31 Technomed International (Societe Anonyme) Use of at least one composite piezoelectric transducer in the manufacture of an ultrasonic therapy apparatus for applying therapy, in a body zone, in particular to concretions, to tissue, or to bones, of a living being and method of ultrasonic therapy
DE69215722T3 (en) 1991-03-22 2001-03-08 Katsuro Tachibana Amplifiers for ultrasound therapy of diseases and liquid pharmaceutical compositions containing them
US5170604A (en) 1991-08-21 1992-12-15 Tamer Industries, Inc. Wall panel system and fastener therefor
JP3533217B2 (en) 1991-12-20 2004-05-31 テクノメド メディカル システム Ultrasound therapy device that outputs ultrasonic waves having thermal effect and cavitation effect
US5476368A (en) 1992-08-20 1995-12-19 Ryder International Corporation Sterile fluid pump diaphragm construction
AU5457394A (en) * 1992-11-02 1994-05-24 Drexel University Surfactant-stabilized microbubble mixtures, process for preparing and methods of using the same
US5573497A (en) 1994-11-30 1996-11-12 Technomed Medical Systems And Institut National High-intensity ultrasound therapy method and apparatus with controlled cavitation effect and reduced side lobes
AU694135B2 (en) * 1993-07-30 1998-07-16 Imcor Pharmaceutical Company Stabilized microbubble compositions for ultrasound
US5419761A (en) 1993-08-03 1995-05-30 Misonix, Inc. Liposuction apparatus and associated method
FR2710962B1 (en) 1993-10-07 1995-11-24 Lpg Systems Solenoid valve and new type of massage device using such a solenoid valve.
GB9322014D0 (en) * 1993-10-26 1993-12-15 Co Ordinated Drug Dev Improvements in and relating to carrier particles for use in dry powder inhalers
US5507790A (en) * 1994-03-21 1996-04-16 Weiss; William V. Method of non-invasive reduction of human site-specific subcutaneous fat tissue deposits by accelerated lipolysis metabolism
US5649547A (en) * 1994-03-24 1997-07-22 Biopsys Medical, Inc. Methods and devices for automated biopsy and collection of soft tissue
US5458596A (en) 1994-05-06 1995-10-17 Dorsal Orthopedic Corporation Method and apparatus for controlled contraction of soft tissue
US6277116B1 (en) 1994-05-06 2001-08-21 Vidaderm Systems and methods for shrinking collagen in the dermis
FR2723310B1 (en) 1994-08-05 1996-09-06 Lpg Systems MASSAGE APPARATUS EXERCISING SUCTION AND MOBILIZATION OF SKIN TISSUE
US5509896A (en) 1994-09-09 1996-04-23 Coraje, Inc. Enhancement of thrombolysis with external ultrasound
US6397098B1 (en) * 1994-09-21 2002-05-28 Medrad, Inc. Data communication and control for medical imaging systems
US6470216B1 (en) 1995-05-05 2002-10-22 Thermage, Inc. Method for smoothing contour irregularities of skin surface
US6425912B1 (en) 1995-05-05 2002-07-30 Thermage, Inc. Method and apparatus for modifying skin surface and soft tissue structure
US5755753A (en) 1995-05-05 1998-05-26 Thermage, Inc. Method for controlled contraction of collagen tissue
US5855775A (en) 1995-05-05 1999-01-05 Kerfoot; William B. Microporous diffusion apparatus
US6241753B1 (en) 1995-05-05 2001-06-05 Thermage, Inc. Method for scar collagen formation and contraction
US5660836A (en) 1995-05-05 1997-08-26 Knowlton; Edward W. Method and apparatus for controlled contraction of collagen tissue
US7422574B2 (en) * 1995-05-19 2008-09-09 Applied Tissue Technologies, Llc Microseeding device for gene delivery by microneedle injection
US5980517A (en) * 1995-08-15 1999-11-09 Rita Medical Systems, Inc. Cell necrosis apparatus
US5590657A (en) 1995-11-06 1997-01-07 The Regents Of The University Of Michigan Phased array ultrasound system and method for cardiac ablation
US7452358B2 (en) 1996-01-05 2008-11-18 Thermage, Inc. RF electrode assembly for handpiece
US7473251B2 (en) 1996-01-05 2009-01-06 Thermage, Inc. Methods for creating tissue effect utilizing electromagnetic energy and a reverse thermal gradient
US6350276B1 (en) 1996-01-05 2002-02-26 Thermage, Inc. Tissue remodeling apparatus containing cooling fluid
US6321109B2 (en) * 1996-02-15 2001-11-20 Biosense, Inc. Catheter based surgery
US5778894A (en) 1996-04-18 1998-07-14 Elizabeth Arden Co. Method for reducing human body cellulite by treatment with pulsed electromagnetic energy
ATE345682T1 (en) 1996-05-01 2006-12-15 Imarx Pharmaceutical Corp IN VITRO METHOD FOR INTRODUCING NUCLEIC ACIDS INTO A CELL
FR2752159B1 (en) 1996-08-09 1998-09-11 Lpg Systems MASSAGE APPARATUS EXERCISING SUCTION AND MOBILIZATION OF SKIN TISSUE
ATE314097T1 (en) 1996-10-28 2006-01-15 Amersham Health As CONTRAST AGENTS
US5827204A (en) 1996-11-26 1998-10-27 Grandia; Willem Medical noninvasive operations using focused modulated high power ultrasound
US5911700A (en) 1997-03-11 1999-06-15 Microaire Surgical Instruments Power assisted liposuction and lipoinjection equipment
US5885323A (en) 1997-04-25 1999-03-23 Ltv Steel Company, Inc. Foamy slag process using multi-circuit lance
US5937906A (en) * 1997-05-06 1999-08-17 Kozyuk; Oleg V. Method and apparatus for conducting sonochemical reactions and processes using hydrodynamic cavitation
GB2327614B (en) 1997-07-30 2002-03-06 Univ Dundee A hypodermic needle
US6128958A (en) 1997-09-11 2000-10-10 The Regents Of The University Of Michigan Phased array system architecture
FR2768051B1 (en) 1997-09-11 1999-10-08 Lpg Systems MASSAGE APPARATUS EXERCISING SUCTION AND MOBILIZATION OF SKIN TISSUE
US6113558A (en) 1997-09-29 2000-09-05 Angiosonics Inc. Pulsed mode lysis method
US6071239A (en) 1997-10-27 2000-06-06 Cribbs; Robert W. Method and apparatus for lipolytic therapy using ultrasound energy
ZA9811087B (en) 1997-12-04 1999-06-03 Bracco Research Sa Automatic liquid injection system and method
US20080027328A1 (en) * 1997-12-29 2008-01-31 Julia Therapeutics, Llc Multi-focal treatment of skin with acoustic energy
US6464680B1 (en) * 1998-07-29 2002-10-15 Pharmasonics, Inc. Ultrasonic enhancement of drug injection
CA2319583C (en) 1998-02-05 2007-08-07 Miwa Science Laboratory Inc. Ultrasound sonication equipment
US6047215A (en) 1998-03-06 2000-04-04 Sonique Surgical Systems, Inc. Method and apparatus for electromagnetically assisted liposuction
EP2263749B1 (en) 1998-03-27 2017-06-21 The General Hospital Corporation Method for the selective targeting of sebaceous glands
US6039048A (en) 1998-04-08 2000-03-21 Silberg; Barry External ultrasound treatment of connective tissue
EP0953432A1 (en) 1998-04-28 1999-11-03 Academisch Ziekenhuis Utrecht Method and device for interconnecting two objects
US7494488B2 (en) 1998-05-28 2009-02-24 Pearl Technology Holdings, Llc Facial tissue strengthening and tightening device and methods
US6203540B1 (en) 1998-05-28 2001-03-20 Pearl I, Llc Ultrasound and laser face-lift and bulbous lysing device
US6302863B1 (en) 1998-06-16 2001-10-16 Nikolai Tankovich Method for removal of lipids via a perfluorocarbon tumescent solution
US6212433B1 (en) * 1998-07-28 2001-04-03 Radiotherapeutics Corporation Method for treating tumors near the surface of an organ
US20030009153A1 (en) * 1998-07-29 2003-01-09 Pharmasonics, Inc. Ultrasonic enhancement of drug injection
US6443914B1 (en) * 1998-08-10 2002-09-03 Lysonix, Inc. Apparatus and method for preventing and treating cellulite
EP1125121B1 (en) * 1998-10-28 2007-12-12 Covaris, Inc. Apparatus and methods for controlling sonic treatment
US6309355B1 (en) 1998-12-22 2001-10-30 The Regents Of The University Of Michigan Method and assembly for performing ultrasound surgery using cavitation
DE60021063T2 (en) 1999-03-09 2006-05-11 Thermage, Inc., Hayward TREATMENT FOR TREATMENT OF TISSUE
US6575930B1 (en) * 1999-03-12 2003-06-10 Medrad, Inc. Agitation devices and dispensing systems incorporating such agitation devices
US6319230B1 (en) * 1999-05-07 2001-11-20 Scimed Life Systems, Inc. Lateral needle injection apparatus and method
US6582442B2 (en) 2000-02-28 2003-06-24 Dynatronics Corporation Method and system for performing microabrasion
US20040200909A1 (en) 1999-05-28 2004-10-14 Cepheid Apparatus and method for cell disruption
US6366206B1 (en) * 1999-06-02 2002-04-02 Ball Semiconductor, Inc. Method and apparatus for attaching tags to medical and non-medical devices
US6743211B1 (en) * 1999-11-23 2004-06-01 Georgia Tech Research Corporation Devices and methods for enhanced microneedle penetration of biological barriers
US6256533B1 (en) 1999-06-09 2001-07-03 The Procter & Gamble Company Apparatus and method for using an intracutaneous microneedle array
GB9915707D0 (en) 1999-07-05 1999-09-08 Young Michael J R Method and apparatus for focused treatment of subcutaneous blood vessels
KR100302144B1 (en) 1999-08-05 2001-11-01 고한준 connector-type optical transceiver using SOI optical wave-guide
US6430466B1 (en) * 1999-08-23 2002-08-06 General Electric Company System for controlling clamp pressure in an automatic molding machine
JP2001076582A (en) * 1999-09-01 2001-03-23 Matsushita Electric Ind Co Ltd Electronic apparatus
US6237604B1 (en) 1999-09-07 2001-05-29 Scimed Life Systems, Inc. Systems and methods for preventing automatic identification of re-used single use devices
US20040158150A1 (en) 1999-10-05 2004-08-12 Omnisonics Medical Technologies, Inc. Apparatus and method for an ultrasonic medical device for tissue remodeling
US6695781B2 (en) 1999-10-05 2004-02-24 Omnisonics Medical Technologies, Inc. Ultrasonic medical device for tissue remodeling
US6391020B1 (en) * 1999-10-06 2002-05-21 The Regents Of The Univerity Of Michigan Photodisruptive laser nucleation and ultrasonically-driven cavitation of tissues and materials
EP1261307A1 (en) 1999-12-15 2002-12-04 Tensor Technologies, LLC Massage device
EP1244390B1 (en) 1999-12-30 2006-08-16 Pearl Technology Holdings, LLC Face-lifting device
JP3565758B2 (en) 2000-03-09 2004-09-15 株式会社日立製作所 Sensitizer for tumor treatment
WO2001070117A2 (en) 2000-03-23 2001-09-27 Microheart, Inc. Pressure sensor for therapeutic delivery device and method
US6585687B1 (en) * 2000-03-27 2003-07-01 Cordis Corporation Inflatable balloon catheter body construction
US6725095B2 (en) 2000-04-13 2004-04-20 Celsion Corporation Thermotherapy method for treatment and prevention of cancer in male and female patients and cosmetic ablation of tissue
US6537242B1 (en) * 2000-06-06 2003-03-25 Becton, Dickinson And Company Method and apparatus for enhancing penetration of a member for the intradermal sampling or administration of a substance
DE10030620A1 (en) 2000-06-28 2002-01-17 Karlsruhe Forschzent Device for injecting medical preparations under CT / MRI control
JP4454114B2 (en) * 2000-06-30 2010-04-21 株式会社日立メディコ Ultrasonic therapy device
US6892099B2 (en) 2001-02-08 2005-05-10 Minnesota Medical Physics, Llc Apparatus and method for reducing subcutaneous fat deposits, virtual face lift and body sculpturing by electroporation
US6795728B2 (en) 2001-08-17 2004-09-21 Minnesota Medical Physics, Llc Apparatus and method for reducing subcutaneous fat deposits by electroporation
GB2366286A (en) * 2000-08-29 2002-03-06 Almedica Europ Ltd Blister pack
US6910671B1 (en) 2000-09-06 2005-06-28 Illinois Tool Works Inc. Shock mount assembly with polymeric thimble tube
DE20016945U1 (en) * 2000-09-30 2002-02-14 Braun Melsungen Ag withdrawal spike
US6882884B1 (en) 2000-10-13 2005-04-19 Soundskin, L.L.C. Process for the stimulation of production of extracellular dermal proteins in human tissue
US6626854B2 (en) 2000-12-27 2003-09-30 Insightec - Txsonics Ltd. Systems and methods for ultrasound assisted lipolysis
US6645162B2 (en) 2000-12-27 2003-11-11 Insightec - Txsonics Ltd. Systems and methods for ultrasound assisted lipolysis
US7347855B2 (en) 2001-10-29 2008-03-25 Ultrashape Ltd. Non-invasive ultrasonic body contouring
US6607498B2 (en) 2001-01-03 2003-08-19 Uitra Shape, Inc. Method and apparatus for non-invasive body contouring by lysing adipose tissue
JP4727903B2 (en) 2001-01-03 2011-07-20 ウルトラシェイプ リミティド Non-invasive ultrasound body contouring
US20020099356A1 (en) 2001-01-19 2002-07-25 Unger Evan C. Transmembrane transport apparatus and method
US6826429B2 (en) 2001-01-19 2004-11-30 Dynatronics Corporation Interferential current treatment apparatus
US6514220B2 (en) 2001-01-25 2003-02-04 Walnut Technologies Non focussed method of exciting and controlling acoustic fields in animal body parts
US7422586B2 (en) 2001-02-28 2008-09-09 Angiodynamics, Inc. Tissue surface treatment apparatus and method
WO2002067796A1 (en) * 2001-02-28 2002-09-06 Rex Medical, L.P. Apparatus for delivering ablation fluid to treat neoplasms
US7087040B2 (en) * 2001-02-28 2006-08-08 Rex Medical, L.P. Apparatus for delivering ablation fluid to treat lesions
US6605079B2 (en) 2001-03-02 2003-08-12 Erchonia Patent Holdings, Llc Method for performing lipoplasty using external laser radiation
US7083580B2 (en) 2001-04-06 2006-08-01 Mattioli Engineering Ltd. Method and apparatus for skin absorption enhancement and transdermal drug delivery
US6743215B2 (en) 2001-04-06 2004-06-01 Mattioli Engineering Ltd. Method and apparatus for skin absorption enhancement and cellulite reduction
US6687537B2 (en) 2001-04-06 2004-02-03 Mattioli Engineering Ltd. Method and apparatus for skin absorption enhancement and cellulite reduction
WO2002087692A1 (en) 2001-04-26 2002-11-07 The Procter & Gamble Company A method and apparatus for the treatment of cosmetic skin conditioins
US6942169B2 (en) 2001-06-06 2005-09-13 Integrated Sensing Systems Micromachined lysing device and method for performing cell lysis
ITFI20010133A1 (en) 2001-07-13 2003-01-13 El En Spa ANTI-CELLULITE EQUIPMENT WITH COMPOSITE TECHNIQUES
CN100450456C (en) 2001-09-28 2009-01-14 锐达医疗系统公司 Impedance controlled tissue ablation apparatus and method
US6689100B2 (en) 2001-10-05 2004-02-10 Becton, Dickinson And Company Microdevice and method of delivering or withdrawing a substance through the skin of an animal
US6795727B2 (en) 2001-10-17 2004-09-21 Pedro Giammarusti Devices and methods for promoting transcutaneous movement of substances
US6920883B2 (en) * 2001-11-08 2005-07-26 Arthrocare Corporation Methods and apparatus for skin treatment
US6889090B2 (en) 2001-11-20 2005-05-03 Syneron Medical Ltd. System and method for skin treatment using electrical current
AU2002220061A1 (en) 2001-11-29 2003-06-17 Microlin Llc Apparatus and methods for fluid delivery using electroactive needles and implantable electrochemical delivery devices
US6829510B2 (en) 2001-12-18 2004-12-07 Ness Neuromuscular Electrical Stimulation Systems Ltd. Surface neuroprosthetic device having an internal cushion interface system
US20030130628A1 (en) 2002-01-08 2003-07-10 Duffy David M. Method and apparatus for the treatment of scar tissue and wrinkles
US20030139740A1 (en) 2002-01-22 2003-07-24 Syneron Medical Ltd. System and method for treating skin
US20030153905A1 (en) 2002-01-25 2003-08-14 Edwards Stuart Denzil Selective ablation system
WO2004069153A2 (en) 2003-01-27 2004-08-19 Medrad, Inc. Apparatus, system and method for generating bubbles on demand
JP4551090B2 (en) * 2002-02-20 2010-09-22 メディシス テクノロジーズ コーポレイション Ultrasonic treatment and imaging of adipose tissue
US20030171701A1 (en) 2002-03-06 2003-09-11 Eilaz Babaev Ultrasonic method and device for lypolytic therapy
US6662054B2 (en) 2002-03-26 2003-12-09 Syneron Medical Ltd. Method and system for treating skin
US20030187371A1 (en) 2002-03-27 2003-10-02 Insightec-Txsonics Ltd. Systems and methods for enhanced focused ultrasound ablation using microbubbles
US7722595B2 (en) * 2002-05-06 2010-05-25 Becton, Dickinson And Company Method and device for controlling drug pharmacokinetics
US20030212350A1 (en) 2002-05-13 2003-11-13 Mark Tadlock Apparatus and method for treating scar tissue
EP1538980B1 (en) 2002-06-25 2017-01-18 Ultrashape Ltd. Device for body aesthetics
US7740600B2 (en) 2002-08-02 2010-06-22 Candela Corporation Apparatus and method for inhibiting pain signals transmitted during a skin related medical treatment
US7250047B2 (en) 2002-08-16 2007-07-31 Lumenis Ltd. System and method for treating tissue
US20040073144A1 (en) 2002-10-11 2004-04-15 Carava Alma Delia Devices and methods for applying negative pressure to body surfaces
US20040120861A1 (en) 2002-10-11 2004-06-24 Affymetrix, Inc. System and method for high-throughput processing of biological probe arrays
US20040083536A1 (en) * 2002-10-30 2004-05-06 I-Chang Hung Elastic health belt
US20060264926A1 (en) 2002-11-08 2006-11-23 Kochamba Gary S Cutaneous stabilization by vacuum for delivery of micro-needle array
US7483738B2 (en) * 2002-11-29 2009-01-27 Power Paper Ltd. Combination stimulating and exothermic heating device and method of use thereof
US7374551B2 (en) 2003-02-19 2008-05-20 Pittsburgh Plastic Surgery Research Associates Minimally invasive fat cavitation method
US6918907B2 (en) * 2003-03-13 2005-07-19 Boston Scientific Scimed, Inc. Surface electrode multiple mode operation
EP1608267A4 (en) * 2003-03-31 2007-04-25 Liposonix Inc Vortex transducer
US9149322B2 (en) 2003-03-31 2015-10-06 Edward Wells Knowlton Method for treatment of tissue
US20040215110A1 (en) 2003-04-24 2004-10-28 Syneron Medical Ltd. Method and device for adipose tissue treatment
JP2007500251A (en) 2003-06-13 2007-01-11 ベクトン・ディキンソン・アンド・カンパニー Improved intradermal delivery of biologically active agents
US20040251566A1 (en) * 2003-06-13 2004-12-16 Kozyuk Oleg V. Device and method for generating microbubbles in a liquid using hydrodynamic cavitation
US20040253148A1 (en) 2003-06-16 2004-12-16 Leaton John R. Multiple probe expansion (MPX™) accessory device for manual, semi-automated and automated liquid handling equipment federally sponsored research
WO2005011804A2 (en) 2003-07-31 2005-02-10 Costantino Peter D Ultasound treatment and imaging system
US20050050018A1 (en) * 2003-09-03 2005-03-03 International Business Machines Corporation Data structure supporting session timer and variable aging function including self adjustable 2MSL
EP1663394B1 (en) 2003-09-08 2014-05-21 The Board Of Trustees Of The University Of Arkansas Ultrasound apparatus for augmented clot lysis
US20050055018A1 (en) 2003-09-08 2005-03-10 Michael Kreindel Method and device for sub-dermal tissue treatment
US7588557B2 (en) * 2003-09-24 2009-09-15 Granit-Medical Innovations, Llc Medical instrument for fluid injection and related method
CA2546265A1 (en) 2003-12-30 2005-07-21 Liposonix, Inc. Systems and methods for the destruction of adipose tissue
US7857773B2 (en) * 2003-12-30 2010-12-28 Medicis Technologies Corporation Apparatus and methods for the destruction of adipose tissue
US9254213B2 (en) * 2004-01-09 2016-02-09 Rubicon Medical, Inc. Stent delivery device
US7351246B2 (en) * 2004-01-20 2008-04-01 Epley John M Minimally invasive, sustained, intra-tympanic drug delivery system
JP2005245521A (en) 2004-03-01 2005-09-15 Japan Natural Laboratory Co Ltd Skin care or beauty system using ion introducer, ultrasonic wave facial treatment device, and cosmetic additives
TWI371454B (en) 2004-04-23 2012-09-01 Supresta Llc Process for the alkylation of phosphorus-containing compounds
US20080319377A1 (en) 2004-05-04 2008-12-25 James Keenan Medical Device for Generating Transient Bubbles
US8133180B2 (en) 2004-10-06 2012-03-13 Guided Therapy Systems, L.L.C. Method and system for treating cellulite
US20060094988A1 (en) 2004-10-28 2006-05-04 Tosaya Carol A Ultrasonic apparatus and method for treating obesity or fat-deposits or for delivering cosmetic or other bodily therapy
US7524318B2 (en) * 2004-10-28 2009-04-28 Boston Scientific Scimed, Inc. Ablation probe with flared electrodes
US20060100555A1 (en) 2004-11-05 2006-05-11 Cagle Merry M Apparatus and system for treating cellulite
US20060122509A1 (en) * 2004-11-24 2006-06-08 Liposonix, Inc. System and methods for destroying adipose tissue
PL2058020T3 (en) 2005-02-01 2013-03-29 Kaleo Inc Devices for medicament delivery
US20060206040A1 (en) 2005-03-09 2006-09-14 Greenberg Ronald A aparatus and method of body contouring and skin conditioning using a mobile suction device
US7857775B2 (en) 2005-03-15 2010-12-28 Syneron Medical Ltd. Method for soft tissue treatment
EP1874197A4 (en) 2005-04-12 2010-02-10 Ekos Corp Ultrasound catheter with cavitation promoting surface
US20070005091A1 (en) 2005-04-21 2007-01-04 Zadini Filiberto P Infra-epidermic subcision device for blunt dissection of sub-epidermic tissues
JP5340728B2 (en) * 2005-06-07 2013-11-13 コーニンクレッカ フィリップス エヌ ヴェ Method and apparatus for ultrasonic drug delivery and thermal treatment with phase variable fluid
KR100652795B1 (en) * 2005-06-30 2006-12-01 주식회사 하이닉스반도체 Method for forming storagenode contact in semiconductor device using metal hardmask contain nitrogen component
US20070031482A1 (en) 2005-08-02 2007-02-08 Ceramoptec Industries, Ind. PDT treatment method for cellulites and cosmetic use
US7837626B2 (en) 2005-08-05 2010-11-23 Siemens Medical Solutions Usa, Inc. Contrast agent manipulation with medical ultrasound imaging
US7591996B2 (en) * 2005-08-17 2009-09-22 University Of Washington Ultrasound target vessel occlusion using microbubbles
US7967763B2 (en) 2005-09-07 2011-06-28 Cabochon Aesthetics, Inc. Method for treating subcutaneous tissues
WO2007030415A2 (en) 2005-09-07 2007-03-15 The Foundry, Inc. Apparatus and method for disrupting subcutaneous structures
US8057408B2 (en) * 2005-09-22 2011-11-15 The Regents Of The University Of Michigan Pulsed cavitational ultrasound therapy
US8257338B2 (en) * 2006-10-27 2012-09-04 Artenga, Inc. Medical microbubble generation
US20080014627A1 (en) * 2005-12-02 2008-01-17 Cabochon Aesthetics, Inc. Devices and methods for selectively lysing cells
BRPI0706605B8 (en) 2006-01-17 2021-06-22 Endymed Medical Ltd electrosurgical system employing phase-controlled radiofrequency energy
US8133191B2 (en) 2006-02-16 2012-03-13 Syneron Medical Ltd. Method and apparatus for treatment of adipose tissue
US9107798B2 (en) 2006-03-09 2015-08-18 Slender Medical Ltd. Method and system for lipolysis and body contouring
US20070282318A1 (en) 2006-05-16 2007-12-06 Spooner Gregory J Subcutaneous thermolipolysis using radiofrequency energy
US20080109023A1 (en) 2006-11-03 2008-05-08 Greer Steven E Method and apparatus for altering the appearance of a patient's skin
US20100106064A1 (en) 2007-03-19 2010-04-29 Syneron Medical Ltd. Method and device for soft tissue destruction
US20090012434A1 (en) 2007-07-03 2009-01-08 Anderson Robert S Apparatus, method, and system to treat a volume of skin
US8103355B2 (en) 2007-07-16 2012-01-24 Invasix Ltd Method and device for minimally invasive skin and fat treatment
US8568339B2 (en) 2007-08-16 2013-10-29 Ultrashape Ltd. Single element ultrasound transducer with multiple driving circuits
US20090125013A1 (en) 2007-11-13 2009-05-14 Roza Sypniewski Fat retraction apparatus and method for using same

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020169394A1 (en) * 1993-11-15 2002-11-14 Eppstein Jonathan A. Integrated tissue poration, fluid harvesting and analysis device, and method therefor
US5884631A (en) * 1997-04-17 1999-03-23 Silberg; Barry Body contouring technique and apparatus
US6375634B1 (en) * 1997-11-19 2002-04-23 Oncology Innovations, Inc. Apparatus and method to encapsulate, kill and remove malignancies, including selectively increasing absorption of x-rays and increasing free-radical damage to residual tumors targeted by ionizing and non-ionizing radiation therapy
US6500141B1 (en) * 1998-01-08 2002-12-31 Karl Storz Gmbh & Co. Kg Apparatus and method for treating body tissue, in particular soft surface tissue with ultrasound
US6896659B2 (en) * 1998-02-06 2005-05-24 Point Biomedical Corporation Method for ultrasound triggered drug delivery using hollow microbubbles with controlled fragility
US6685657B2 (en) * 1998-11-20 2004-02-03 Joie P. Jones Methods for selectively dissolving and removing materials using ultra-high frequency ultrasound
US6916328B2 (en) * 2001-11-15 2005-07-12 Expanding Concepts, L.L.C Percutaneous cellulite removal system

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP1940300A4 *

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US20070055180A1 (en) 2007-03-08
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US20070055179A1 (en) 2007-03-08
US20090275879A1 (en) 2009-11-05
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US20090275899A1 (en) 2009-11-05
US7601128B2 (en) 2009-10-13

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