WO2007059328A3 - Selective molecular transport through modified disc shunt - Google Patents
Selective molecular transport through modified disc shunt Download PDFInfo
- Publication number
- WO2007059328A3 WO2007059328A3 PCT/US2006/044795 US2006044795W WO2007059328A3 WO 2007059328 A3 WO2007059328 A3 WO 2007059328A3 US 2006044795 W US2006044795 W US 2006044795W WO 2007059328 A3 WO2007059328 A3 WO 2007059328A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- disc
- vertebral bodies
- bonding
- molecular transport
- selective molecular
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0069—Devices for implanting pellets, e.g. markers or solid medicaments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/34—Trocars; Puncturing needles
- A61B17/3478—Endoscopic needles, e.g. for infusion
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
- A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
- A61B17/70—Spinal positioners or stabilisers ; Bone stabilisers comprising fluid filler in an implant
- A61B17/7061—Spinal positioners or stabilisers ; Bone stabilisers comprising fluid filler in an implant for stabilising vertebrae or discs by improving the condition of their tissues, e.g. using implanted medication or fluid exchange
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/00234—Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery
- A61B2017/00238—Type of minimally invasive operation
- A61B2017/00261—Discectomy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/44—Joints for the spine, e.g. vertebrae, spinal discs
- A61F2/442—Intervertebral or spinal discs, e.g. resilient
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Surgery (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Pathology (AREA)
- Dermatology (AREA)
- Anesthesiology (AREA)
- Hematology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
The disc contains no blood vessels. Nutrients and oxygen essential to disc cells are diffused from adjacent vertebral bodies into the disc. As we age, calcified layers form between the disc and vertebral bodies, blocking diffusion. The disc begins to starve and flatten. The weight shifts abnormally from disc to the facet joints causing strain and pain. Hydrophilic or charged groups are proposed bonding to disc shunts to facilitate the exchange between the avascular disc and bodily circulation. In addition, bonding of cleavable hydrophobic groups delays or hinders transport to minimize infiltration of immunoglobulins or cytokines into the immuno-isolated disc.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US73845005P | 2005-11-19 | 2005-11-19 | |
US60/738,450 | 2005-11-19 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2007059328A2 WO2007059328A2 (en) | 2007-05-24 |
WO2007059328A3 true WO2007059328A3 (en) | 2008-01-31 |
Family
ID=38049322
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2006/044795 WO2007059328A2 (en) | 2005-11-19 | 2006-11-17 | Selective molecular transport through modified disc shunt |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2007059328A2 (en) |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002017825A2 (en) * | 2000-08-28 | 2002-03-07 | Disc Dynamics, Inc. | Intervertebral disc prosthesis |
US20040024400A1 (en) * | 1994-05-27 | 2004-02-05 | Michelson Gary Karlin | Method for the delivery of electrical current to promote bone growth between adjacent bone masses |
WO2004101015A2 (en) * | 2003-05-07 | 2004-11-25 | Aleeva Medical, Inc. | Device for treating back pain by re-establishing the exchange of nutrient & waste |
-
2006
- 2006-11-17 WO PCT/US2006/044795 patent/WO2007059328A2/en active Application Filing
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040024400A1 (en) * | 1994-05-27 | 2004-02-05 | Michelson Gary Karlin | Method for the delivery of electrical current to promote bone growth between adjacent bone masses |
WO2002017825A2 (en) * | 2000-08-28 | 2002-03-07 | Disc Dynamics, Inc. | Intervertebral disc prosthesis |
WO2004101015A2 (en) * | 2003-05-07 | 2004-11-25 | Aleeva Medical, Inc. | Device for treating back pain by re-establishing the exchange of nutrient & waste |
Also Published As
Publication number | Publication date |
---|---|
WO2007059328A2 (en) | 2007-05-24 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
121 | Ep: the epo has been informed by wipo that ep was designated in this application | ||
NENP | Non-entry into the national phase |
Ref country code: DE |
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122 | Ep: pct application non-entry in european phase |
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