WO2007067780A3 - Combination therapy and antibody panels - Google Patents
Combination therapy and antibody panels Download PDFInfo
- Publication number
- WO2007067780A3 WO2007067780A3 PCT/US2006/047077 US2006047077W WO2007067780A3 WO 2007067780 A3 WO2007067780 A3 WO 2007067780A3 US 2006047077 W US2006047077 W US 2006047077W WO 2007067780 A3 WO2007067780 A3 WO 2007067780A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- immunoglobulin
- combination immunotherapy
- combination therapy
- idiotypic
- administration
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
- C07K16/4283—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an allotypic or isotypic determinant on Ig
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39566—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against immunoglobulins, e.g. anti-idiotypic antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3061—Blood cells
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Abstract
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA002632744A CA2632744A1 (en) | 2005-12-08 | 2006-12-08 | Combination therapy and antibody panels |
GB0812408A GB2448627B (en) | 2005-12-08 | 2008-07-07 | Combination therapy and antibody panels |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11/297,168 US20070134249A1 (en) | 2005-12-08 | 2005-12-08 | Combination therapy and antibody panels |
US11/297,167 US20070134248A1 (en) | 2005-12-08 | 2005-12-08 | Combination therapy and antibody panels |
US11/297,167 | 2005-12-08 | ||
US11/297,168 | 2005-12-08 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2007067780A2 WO2007067780A2 (en) | 2007-06-14 |
WO2007067780A3 true WO2007067780A3 (en) | 2008-05-02 |
Family
ID=38123554
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2006/047077 WO2007067780A2 (en) | 2005-12-08 | 2006-12-08 | Combination therapy and antibody panels |
Country Status (3)
Country | Link |
---|---|
CA (1) | CA2632744A1 (en) |
GB (1) | GB2448627B (en) |
WO (1) | WO2007067780A2 (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2922212B1 (en) * | 2007-10-11 | 2011-11-11 | France Etat | ANTIBODY ANTIBODY |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5227159A (en) * | 1989-01-31 | 1993-07-13 | Miller Richard A | Anti-idiotype antibodies reactive with shared idiotopes expressed by B cell lymphomas and autoantibodies |
US20030129628A1 (en) * | 1992-03-09 | 2003-07-10 | Sybille Muller | Anti-idiotypic antibody and its use in diagnosis and therapy in HIV-related disease |
US6706484B1 (en) * | 1995-08-18 | 2004-03-16 | Morphosys Ag | Protein/(poly)peptide libraries |
-
2006
- 2006-12-08 CA CA002632744A patent/CA2632744A1/en not_active Abandoned
- 2006-12-08 WO PCT/US2006/047077 patent/WO2007067780A2/en active Application Filing
-
2008
- 2008-07-07 GB GB0812408A patent/GB2448627B/en not_active Expired - Fee Related
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5227159A (en) * | 1989-01-31 | 1993-07-13 | Miller Richard A | Anti-idiotype antibodies reactive with shared idiotopes expressed by B cell lymphomas and autoantibodies |
US20030129628A1 (en) * | 1992-03-09 | 2003-07-10 | Sybille Muller | Anti-idiotypic antibody and its use in diagnosis and therapy in HIV-related disease |
US6706484B1 (en) * | 1995-08-18 | 2004-03-16 | Morphosys Ag | Protein/(poly)peptide libraries |
Non-Patent Citations (3)
Title |
---|
DAVIS ET AL.: "Anti-Idiotype Antibodies Can Induce Long-Term Complete Remissions in Non-Hodgkin's Lymphoma Without Eradication the Malignant Clone", BLOOD, vol. 92, August 1998 (1998-08-01), pages 1184 - 1190 * |
NELSON ET AL.: "Tumor - Specific, Cytotoxic T-Lymphocyte Response After Idiotype Vaccination for B-cell, Non-Hodgkin's Lymphoma", BLOOD, vol. 88, July 1996 (1996-07-01), pages 580 - 589 * |
RUFFINI ET AL.: "Idiotypic vaccination for B-cell malignancies as a model for therapeutic cancer vaccines: from prototype protein to second generation vaccines", HAEMATOLOGICA, vol. 87, September 2002 (2002-09-01), pages 989 - 1001 * |
Also Published As
Publication number | Publication date |
---|---|
CA2632744A1 (en) | 2007-06-14 |
WO2007067780A2 (en) | 2007-06-14 |
GB0812408D0 (en) | 2008-08-13 |
GB2448627A (en) | 2008-10-22 |
GB2448627B (en) | 2010-07-14 |
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