WO2007075931A3 - Reactive heterocyclic derivatives and methods for their synthesis and use - Google Patents

Reactive heterocyclic derivatives and methods for their synthesis and use Download PDF

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Publication number
WO2007075931A3
WO2007075931A3 PCT/US2006/048864 US2006048864W WO2007075931A3 WO 2007075931 A3 WO2007075931 A3 WO 2007075931A3 US 2006048864 W US2006048864 W US 2006048864W WO 2007075931 A3 WO2007075931 A3 WO 2007075931A3
Authority
WO
WIPO (PCT)
Prior art keywords
synthesis
methods
heterocyclic derivatives
reactive heterocyclic
reactive
Prior art date
Application number
PCT/US2006/048864
Other languages
French (fr)
Other versions
WO2007075931A2 (en
Inventor
Joseph Barry Noar
Mariusz G Banaszczyk
Violeta Millan
Gunars Valkirs
Kenneth F Buechler
Brian Noland
Original Assignee
Biosite Inc
Joseph Barry Noar
Mariusz G Banaszczyk
Violeta Millan
Gunars Valkirs
Kenneth F Buechler
Brian Noland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biosite Inc, Joseph Barry Noar, Mariusz G Banaszczyk, Violeta Millan, Gunars Valkirs, Kenneth F Buechler, Brian Noland filed Critical Biosite Inc
Publication of WO2007075931A2 publication Critical patent/WO2007075931A2/en
Publication of WO2007075931A3 publication Critical patent/WO2007075931A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Abstract

The present invention describes molecules having a core structure that is an indole or an indolene that is modified to provide a functional moiety, and methods for their synthesis and use. Such functionalized heterocyclic derivatives may be used in a variety of assay formats.
PCT/US2006/048864 2005-12-22 2006-12-22 Reactive heterocyclic derivatives and methods for their synthesis and use WO2007075931A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US81362105P 2005-12-22 2005-12-22
US60/813,621 2005-12-22

Publications (2)

Publication Number Publication Date
WO2007075931A2 WO2007075931A2 (en) 2007-07-05
WO2007075931A3 true WO2007075931A3 (en) 2007-11-08

Family

ID=38218634

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/048864 WO2007075931A2 (en) 2005-12-22 2006-12-22 Reactive heterocyclic derivatives and methods for their synthesis and use

Country Status (1)

Country Link
WO (1) WO2007075931A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2990076B1 (en) 2012-04-27 2015-08-21 Labinal CURRENT RETURN LINK HARNESS, AND METHOD OF MOUNTING ON A COMPOSITE FUSELAGE FRAME
SG11201703729RA (en) * 2014-11-19 2017-06-29 Nestec Sa Antibodies against serotonin, tryptophan and kynurenine metabolites and uses thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5268486A (en) * 1986-04-18 1993-12-07 Carnegie-Mellon Unversity Method for labeling and detecting materials employing arylsulfonate cyanine dyes
US6503907B2 (en) * 2000-11-28 2003-01-07 Hoffmann-La Roche Inc. Indole and dihydroindole derivatives
US20030054356A1 (en) * 2000-09-21 2003-03-20 Jacobson James W. Multiple reporter read-out for bioassays

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5268486A (en) * 1986-04-18 1993-12-07 Carnegie-Mellon Unversity Method for labeling and detecting materials employing arylsulfonate cyanine dyes
US20030054356A1 (en) * 2000-09-21 2003-03-20 Jacobson James W. Multiple reporter read-out for bioassays
US6503907B2 (en) * 2000-11-28 2003-01-07 Hoffmann-La Roche Inc. Indole and dihydroindole derivatives

Also Published As

Publication number Publication date
WO2007075931A2 (en) 2007-07-05

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