WO2007082304A3 - Biodegradable elastomers - Google Patents
Biodegradable elastomers Download PDFInfo
- Publication number
- WO2007082304A3 WO2007082304A3 PCT/US2007/060529 US2007060529W WO2007082304A3 WO 2007082304 A3 WO2007082304 A3 WO 2007082304A3 US 2007060529 W US2007060529 W US 2007060529W WO 2007082304 A3 WO2007082304 A3 WO 2007082304A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- polymers
- acrylated
- polymer
- elastic biodegradable
- cross
- Prior art date
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/04—Macromolecular materials
- A61L31/06—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/48—Reproductive organs
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/58—Materials at least partially resorbable by the body
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/148—Materials at least partially resorbable by the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
- C08G63/68—Polyesters containing atoms other than carbon, hydrogen and oxygen
- C08G63/685—Polyesters containing atoms other than carbon, hydrogen and oxygen containing nitrogen
- C08G63/6854—Polyesters containing atoms other than carbon, hydrogen and oxygen containing nitrogen derived from polycarboxylic acids and polyhydroxy compounds
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J3/00—Processes of treating or compounding macromolecular substances
- C08J3/24—Crosslinking, e.g. vulcanising, of macromolecules
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J3/00—Processes of treating or compounding macromolecular substances
- C08J3/24—Crosslinking, e.g. vulcanising, of macromolecules
- C08J3/246—Intercrosslinking of at least two polymers
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
- C08K5/00—Use of organic ingredients
- C08K5/0008—Organic ingredients according to more than one of the "one dot" groups of C08K5/01 - C08K5/59
- C08K5/0025—Crosslinking or vulcanising agents; including accelerators
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
- C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
- C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
- C12N11/082—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds
- C12N11/087—Acrylic polymers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
- C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
- C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
- C12N11/089—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
- C12N11/096—Polyesters; Polyamides
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2367/00—Characterised by the use of polyesters obtained by reactions forming a carboxylic ester link in the main chain; Derivatives of such polymers
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2367/00—Characterised by the use of polyesters obtained by reactions forming a carboxylic ester link in the main chain; Derivatives of such polymers
- C08J2367/06—Unsaturated polyesters
- C08J2367/07—Unsaturated polyesters having terminal carbon-to-carbon unsaturated bonds
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
- C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
- C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
- C12N11/082—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds
Abstract
The present inventions in various aspects provide elastic biodegradable polymers. In various embodiments, the polymers are formed by the reaction of a multifunctional alcohol or ether and a difunctional or higher order acid to form a prepolymer.. which is cross-linked to form the elastic biodegradable polymer. In preferred embodiments, the cross-linking is performed by functionalization of one or more OR groups on the pre-polymer backbone with vinyl, followed by photopolymerization to form the elastic biodegradable polymer composition or material. Preferably, acrylate is used to add one or more vinyls to the backbone of the pre-polymer to form an acrylated pre-polyrøer. In various embodiments, acrylated pre-polymers are co-polymerized with one or more acrylated co-polymers.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US75897306P | 2006-01-12 | 2006-01-12 | |
US60/758,973 | 2006-01-12 | ||
US80322306P | 2006-05-25 | 2006-05-25 | |
US60/803,223 | 2006-05-25 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2007082304A2 WO2007082304A2 (en) | 2007-07-19 |
WO2007082304A3 true WO2007082304A3 (en) | 2007-11-15 |
Family
ID=38257139
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2007/060532 WO2007082305A2 (en) | 2006-01-12 | 2007-01-12 | Biodegradable elastomers |
PCT/US2007/060529 WO2007082304A2 (en) | 2006-01-12 | 2007-01-12 | Biodegradable elastomers |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2007/060532 WO2007082305A2 (en) | 2006-01-12 | 2007-01-12 | Biodegradable elastomers |
Country Status (6)
Country | Link |
---|---|
US (5) | US8143042B2 (en) |
EP (1) | EP1973493A2 (en) |
JP (1) | JP2009523864A (en) |
AU (1) | AU2007204617A1 (en) |
CA (1) | CA2636817C (en) |
WO (2) | WO2007082305A2 (en) |
Families Citing this family (90)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7431710B2 (en) | 2002-04-08 | 2008-10-07 | Glaukos Corporation | Ocular implants with anchors and methods thereof |
US7722894B2 (en) * | 2001-10-22 | 2010-05-25 | Massachusetts Institute Of Technology | Biodegradable polymer |
KR100665672B1 (en) | 2005-04-13 | 2007-01-09 | 성균관대학교산학협력단 | Temperature and ph sensitive block copolymer and polymeric hydrogles using the same |
US20100003297A1 (en) * | 2005-08-11 | 2010-01-07 | Massachusetts Institute Of Technology | Implantable Drug Delivery Device and Methods of Treating Male Genitourinary and Surrounding Tissues |
AU2007204617A1 (en) | 2006-01-12 | 2007-07-19 | Massachusetts Institute Of Technology | Biodegradable elastomers |
US20090011486A1 (en) * | 2006-01-12 | 2009-01-08 | Massachusetts Institute Of Technology | Biodegradable Elastomers |
WO2007136354A1 (en) * | 2006-05-24 | 2007-11-29 | Agency For Science, Technology And Research | Bioactive surface for hepatocyte-based applications |
US8912304B2 (en) * | 2007-05-17 | 2014-12-16 | Massachusetts Institute Of Technology | Polyol-based polymers |
WO2010003076A2 (en) * | 2008-07-03 | 2010-01-07 | Vesseltek Biomedical, Llc | Controlled and localized release of retinoids to improve neointimal hyperplasia |
EP2331606B1 (en) | 2008-09-19 | 2016-11-02 | Northwestern University | Biodegradable nitric oxide generating polymers and related biomedical devices |
US8163861B2 (en) | 2009-01-15 | 2012-04-24 | Living Proof, Inc. | Beta-amino ester compounds and uses thereof |
US10206813B2 (en) | 2009-05-18 | 2019-02-19 | Dose Medical Corporation | Implants with controlled drug delivery features and methods of using same |
DE102009027244A1 (en) * | 2009-06-26 | 2010-12-30 | Evonik Röhm Gmbh | Process for producing a foam part from crosslinked poly (meth) acrylates and the foam and its use |
AU2010286604A1 (en) * | 2009-08-28 | 2012-03-08 | Innovative Health Technologies, Llc | Polymer adhesive film for directed cellular growth |
US20170238576A9 (en) * | 2009-11-23 | 2017-08-24 | Xiaohu Xia | Gum bases containing non-uniform crosslinked polymer microparticles |
US20110123672A1 (en) * | 2009-11-23 | 2011-05-26 | Xiaohu Xia | Gum bases, chewing gums based thereupon, and methods for making the same |
ES2360546B1 (en) * | 2009-11-25 | 2012-04-19 | Luis Enrique Lopez-Pozas Lanuza | GOLFTEE 100% BIODEGRADABLE. |
WO2011106447A1 (en) * | 2010-02-23 | 2011-09-01 | Georgia Tech Research Corporation | Biodegradable polymeric networks and methods for manufacturing the same |
EP2545100A2 (en) * | 2010-03-09 | 2013-01-16 | Council of Scientific & Industrial Research | A biodegradable polymeric hydrogel composition |
CA2794630A1 (en) * | 2010-05-14 | 2011-11-17 | Liliana Atanasoska | Endoprosthesis |
US8513321B2 (en) | 2010-11-05 | 2013-08-20 | Ppg Industries Ohio, Inc. | Dual cure coating compositions, methods of coating a substrate, and related coated substrates |
US20120143347A1 (en) * | 2010-12-03 | 2012-06-07 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Elastomeric, Polymeric Bone Engineering and Regeneration Compositions and Methods of Making |
US10245178B1 (en) | 2011-06-07 | 2019-04-02 | Glaukos Corporation | Anterior chamber drug-eluting ocular implant |
US10035871B2 (en) | 2011-08-26 | 2018-07-31 | Massachusetts Institute Of Technology | Urethane-crosslinked biodegradable elastomers |
SE537311C2 (en) * | 2011-11-16 | 2015-04-07 | Observe Medical Aps | Arrangement and method for detecting the surface degeneration of a measuring chamber during measurement of urine production |
KR20140102759A (en) | 2011-12-16 | 2014-08-22 | 모더나 세라퓨틱스, 인코포레이티드 | Modified nucleoside, nucleotide, and nucleic acid compositions |
AU2013243949A1 (en) | 2012-04-02 | 2014-10-30 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of biologics and proteins associated with human disease |
CA2868398A1 (en) | 2012-04-02 | 2013-10-10 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of cosmetic proteins and peptides |
WO2014011970A1 (en) * | 2012-07-13 | 2014-01-16 | Global Biomedical Technologies, Llc. | Selectively-releasable adhesives and articles that incorporate them |
US9533072B2 (en) * | 2012-10-08 | 2017-01-03 | Cormatrix Cardiovascular, Inc. | Reinforced vascular prostheses |
EP2907834A4 (en) | 2012-10-09 | 2015-09-30 | Shanghai Microport Medical Group Co Ltd | Biodegradable cross-linked polymer, vascular stent and manufacturing methods therefor |
US20140172074A1 (en) * | 2012-12-13 | 2014-06-19 | 480 Biomedical, Inc. | Stent with reinforced joints |
US10258698B2 (en) | 2013-03-14 | 2019-04-16 | Modernatx, Inc. | Formulation and delivery of modified nucleoside, nucleotide, and nucleic acid compositions |
US9714341B2 (en) | 2013-03-18 | 2017-07-25 | Washington State University | Biodegradable polyester-based blends |
EP3950018A1 (en) * | 2013-05-24 | 2022-02-09 | Massachusetts Institute Of Technology | Hydrophobic tissue adhesives |
US10058455B2 (en) | 2013-06-10 | 2018-08-28 | Ultramend, Inc. | Nano-enhanced wound dressing |
WO2015034928A1 (en) | 2013-09-03 | 2015-03-12 | Moderna Therapeutics, Inc. | Chimeric polynucleotides |
US20160194368A1 (en) | 2013-09-03 | 2016-07-07 | Moderna Therapeutics, Inc. | Circular polynucleotides |
KR102340388B1 (en) | 2013-09-19 | 2021-12-17 | 마이크로벤션, 인코포레이티드 | Polymer films |
EP3046952B1 (en) | 2013-09-19 | 2021-05-12 | Terumo Corporation | Polymer particles |
JP2016538829A (en) | 2013-10-03 | 2016-12-15 | モデルナ セラピューティクス インコーポレイテッドModerna Therapeutics,Inc. | Polynucleotide encoding low density lipoprotein receptor |
KR102287781B1 (en) | 2013-11-08 | 2021-08-06 | 테루모 가부시키가이샤 | Polymer particles |
US10663666B2 (en) * | 2013-12-05 | 2020-05-26 | United States Of America As Represented By The Secretary Of The Navy | Flexible, low profile kink resistant fiber optic splice tension sleeve |
US9801910B2 (en) | 2014-03-17 | 2017-10-31 | Ethicon, Inc. | Decellularized pleural matrix |
AU2015266850B2 (en) | 2014-05-29 | 2019-12-05 | Glaukos Corporation | Implants with controlled drug delivery features and methods of using same |
EP3169693B1 (en) | 2014-07-16 | 2022-03-09 | ModernaTX, Inc. | Chimeric polynucleotides |
EP3171895A1 (en) | 2014-07-23 | 2017-05-31 | Modernatx, Inc. | Modified polynucleotides for the production of intrabodies |
JP2017526432A (en) * | 2014-08-14 | 2017-09-14 | ザ・セカント・グループ・エルエルシー | Compositions, methods, and devices useful for making implantable articles |
US10454036B2 (en) * | 2014-08-21 | 2019-10-22 | Dow Global Technologies Llc | Polymeric charge transfer layer and organic electronic device containing the same |
WO2016086088A2 (en) | 2014-11-25 | 2016-06-02 | Northwestern University | Wound healing through sirt1 overexpression |
US9744261B2 (en) | 2014-12-08 | 2017-08-29 | Cormatrix Cardiovascular, Inc. | Vascular casted prostheses and methods of forming same for treating biological tissue |
WO2016094106A1 (en) * | 2014-12-10 | 2016-06-16 | Cormatrix Cardiovascular, Inc. | Biocompatable annular prostheses and methods for forming same |
WO2016100520A1 (en) * | 2014-12-16 | 2016-06-23 | Boston Scientific Scimed, Inc. | Bioerodible polymer compositions |
WO2016153534A1 (en) * | 2015-03-23 | 2016-09-29 | Cormatrix Cardiovascular, Inc. | Vascular casted prostheses and methods of forming same for treating biological tissue |
US9907880B2 (en) | 2015-03-26 | 2018-03-06 | Microvention, Inc. | Particles |
US11898005B2 (en) | 2015-06-18 | 2024-02-13 | Tissium Sa | Sealant composition |
EP3892665A1 (en) | 2015-06-18 | 2021-10-13 | Tissium SA | Sealant composition |
EP3310403B1 (en) | 2015-06-18 | 2022-03-09 | Tissium SA | Adhesive composition |
US10039858B2 (en) | 2015-08-03 | 2018-08-07 | University of Pittsburgh—Of the Commonweatlh System of Higher Education | Biodegradable poly(ester amide) elastomers and uses therefor |
US11925578B2 (en) | 2015-09-02 | 2024-03-12 | Glaukos Corporation | Drug delivery implants with bi-directional delivery capacity |
WO2017053885A1 (en) | 2015-09-25 | 2017-03-30 | Glaukos Corporation | Punctal implants with controlled drug delivery features and methods of using same |
CN105561377B (en) * | 2015-12-25 | 2018-09-25 | 东华大学 | A kind of degradable photocuring adhesive of medical and its preparation and application |
AU2017252294B2 (en) | 2016-04-20 | 2021-12-02 | Dose Medical Corporation | Bioresorbable ocular drug delivery device |
KR102310696B1 (en) | 2016-09-28 | 2021-10-12 | 테루모 가부시키가이샤 | Embolic composition |
CN107417901A (en) * | 2017-05-19 | 2017-12-01 | 东华大学 | A kind of bionical toughness reinforcing bioelastomer and preparation method thereof |
WO2019050975A1 (en) * | 2017-09-05 | 2019-03-14 | Maguire Abbey, Llc | Method, compositions and articles for improving joint lubrication |
EP4219715A3 (en) | 2017-09-08 | 2023-09-06 | MiNA Therapeutics Limited | Stabilized cebpa sarna compositions and methods of use |
CN111601625B (en) * | 2018-03-15 | 2022-11-08 | 泰尔茂株式会社 | Self-expanding stent and method of making same |
EP3768335A1 (en) | 2018-03-22 | 2021-01-27 | Tissium SA | 3d printing composition for biomaterials |
WO2019197845A1 (en) | 2018-04-12 | 2019-10-17 | Mina Therapeutics Limited | Sirt1-sarna compositions and methods of use |
EP3560427A1 (en) | 2018-04-24 | 2019-10-30 | Gecko Biomedical | Applicator for depositing a layer of adhesive or sealant composition on a biological and/or prosthetic tissue |
WO2020014623A1 (en) * | 2018-07-12 | 2020-01-16 | The Trustees Of The University Of Pennsylvania | Systems for targeted tissue biosealing or repair |
JP2021534101A (en) | 2018-08-09 | 2021-12-09 | ヴェルソー セラピューティクス, インコーポレイテッド | Oligonucleotide compositions for targeting CCR2 and CSF1R and their use |
EP3840732A1 (en) | 2018-08-21 | 2021-06-30 | The Secant Group, LLC | Controlled-release urethane-elastomers for use in implantable products |
CN109705359B (en) * | 2018-12-27 | 2020-09-25 | 华东理工大学 | Modified polyethylene glycol-polysebacic acid (PEGS) injectable biological elastomer and preparation method and application thereof |
EP3680273B1 (en) * | 2019-01-08 | 2022-03-09 | Université de Montpellier | Branched-block copolymer photo-crosslinker functionalized with photoreactive groups and its use for shaping degradable photo-crosslinked elastomers suitable for medical and tissue-engineering applications |
EP3953473A1 (en) | 2019-04-12 | 2022-02-16 | MiNA Therapeutics Limited | Sirt1-sarna compositions and methods of use |
KR20230029571A (en) * | 2019-07-22 | 2023-03-03 | 베노스텐트, 인크. | Additive Manufacturing of Vinyl, Photocrosslinkable Polymers |
US20220380531A1 (en) | 2019-10-25 | 2022-12-01 | Tissium Sa | Composition comprising activated and functionalized prepolymer |
EP4051327A4 (en) * | 2019-11-01 | 2023-11-22 | Allegro 3D, Inc. | 3d-bioprinted scaffolds for tissue regeneration |
EP4132992A1 (en) * | 2020-04-06 | 2023-02-15 | The Secant Group, LLC | Water-mediated polyester (meth)acrylation systems |
US11939444B2 (en) * | 2020-04-09 | 2024-03-26 | The Secant Group, Llc | Modified polymer film surfaces for single-use bioreactor bags and biocontainment and methods of forming same |
GB2603454A (en) | 2020-12-09 | 2022-08-10 | Ucl Business Ltd | Novel therapeutics for the treatment of neurodegenerative disorders |
EP4029457A1 (en) | 2021-01-18 | 2022-07-20 | Tissium | Applicator, kit and method for applying an adhesive composition on a support, such as a tissue repair support |
KR20230133313A (en) | 2021-01-18 | 2023-09-19 | 티시움 에스에이 | surgical materials |
EP4298149A1 (en) | 2021-02-24 | 2024-01-03 | Tissium SA | Composition comprising activated and functionalized pre-polymer |
EP4314292A1 (en) | 2021-03-26 | 2024-02-07 | MiNA Therapeutics Limited | Tmem173 sarna compositions and methods of use |
WO2023099884A1 (en) | 2021-12-01 | 2023-06-08 | Mina Therapeutics Limited | Pax6 sarna compositions and methods of use |
GB202117758D0 (en) | 2021-12-09 | 2022-01-26 | Ucl Business Ltd | Therapeutics for the treatment of neurodegenerative disorders |
WO2023170435A1 (en) | 2022-03-07 | 2023-09-14 | Mina Therapeutics Limited | Il10 sarna compositions and methods of use |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6444782B1 (en) * | 1999-04-26 | 2002-09-03 | Eastman Chemical Company | Process for making pre-gels for a cross-linked branched polyester |
US20050048121A1 (en) * | 2003-06-04 | 2005-03-03 | Polymerix Corporation | High molecular wegiht polymers, devices and method for making and using same |
Family Cites Families (73)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US1489744A (en) * | 1920-12-22 | 1924-04-08 | Barrett Co | Resin and process of producing the same |
US1779367A (en) * | 1929-10-11 | 1930-10-21 | Condensation product and process for preparing same | |
US3830875A (en) * | 1970-10-21 | 1974-08-20 | Gen Tire & Rubber Co | Method of improving paint adhesion to low-shrink polyester-based resins |
BE786148A (en) * | 1971-07-13 | 1973-01-12 | Westinghouse Electric Corp | IMPROVEMENTS TO, OR RELATING TO, THERMOSETTING RESIN ADHESIVE COMPOSITIONS |
JPS5140870B2 (en) | 1972-05-30 | 1976-11-06 | ||
US4048256A (en) * | 1976-06-01 | 1977-09-13 | American Cyanamid Company | Normally-solid, bioabsorbable, hydrolyzable, polymeric reaction product |
US4064086A (en) * | 1976-07-13 | 1977-12-20 | National Patent Development Corporation | Thermoplastic hydrogels |
US4205399A (en) * | 1977-06-13 | 1980-06-03 | Ethicon, Inc. | Synthetic absorbable surgical devices of poly(alkylene oxalates) |
US4177596A (en) * | 1978-02-21 | 1979-12-11 | Dillow John P | Appendage for a fishhook |
GB2056023B (en) * | 1979-08-06 | 1983-08-10 | Ross D N Bodnar E | Stent for a cardiac valve |
US4275169A (en) * | 1979-09-19 | 1981-06-23 | Tenneco Chemicals, Inc. | Intumescent flexible polyurethane foam having incorporated into the reaction mixture an aliphatic aldehyde |
JPS606659B2 (en) | 1981-04-14 | 1985-02-19 | 日清製油株式会社 | solid fragrance deodorant |
DE3123465A1 (en) | 1981-06-12 | 1982-12-30 | Perstorp AB, 28400 Perstorp | Secondary stabiliser, principally for vinyl chloride polymers |
US4946929A (en) * | 1983-03-22 | 1990-08-07 | Massachusetts Institute Of Technology | Bioerodible articles useful as implants and prostheses having predictable degradation rates |
US5286763A (en) | 1983-03-22 | 1994-02-15 | Massachusetts Institute Of Technology | Bioerodible polymers for drug delivery in bone |
US4638045A (en) * | 1985-02-19 | 1987-01-20 | Massachusetts Institute Of Technology | Non-peptide polyamino acid bioerodible polymers |
US4806621A (en) * | 1986-01-21 | 1989-02-21 | Massachusetts Institute Of Technology | Biocompatible, bioerodible, hydrophobic, implantable polyimino carbonate article |
DE3670206D1 (en) | 1986-05-20 | 1990-05-17 | Massachusetts Inst Technology | BIOERODABLE PRODUCTS FOR USE AS IMPLANTS OR PROSTHESIS WITH A PREDICTABLE LEVEL OF RESORBATION. |
US5736372A (en) | 1986-11-20 | 1998-04-07 | Massachusetts Institute Of Technology | Biodegradable synthetic polymeric fibrous matrix containing chondrocyte for in vivo production of a cartilaginous structure |
US5759830A (en) | 1986-11-20 | 1998-06-02 | Massachusetts Institute Of Technology | Three-dimensional fibrous scaffold containing attached cells for producing vascularized tissue in vivo |
CA1340581C (en) | 1986-11-20 | 1999-06-08 | Joseph P. Vacanti | Chimeric neomorphogenesis of organs by controlled cellular implantation using artificial matrices |
US5019379A (en) * | 1987-07-31 | 1991-05-28 | Massachusetts Institute Of Technology | Unsaturated polyanhydrides |
US5505808A (en) | 1989-02-02 | 1996-04-09 | Armstrong World Industries, Inc. | Method to produce an inorganic wear layer |
US5010167A (en) * | 1989-03-31 | 1991-04-23 | Massachusetts Institute Of Technology | Poly(amide-and imide-co-anhydride) for biological application |
JP2907996B2 (en) | 1989-11-08 | 1999-06-21 | 三井化学株式会社 | fishing line |
US5053482A (en) | 1990-05-11 | 1991-10-01 | E. I. Du Pont De Nemours And Company | Novel polyesters and their use in compostable products such as disposable diapers |
US5489298A (en) | 1991-01-24 | 1996-02-06 | Autogenics | Rapid assembly concentric mating stent, tissue heart valve with enhanced clamping and tissue exposure |
SE9100610D0 (en) | 1991-03-04 | 1991-03-04 | Procordia Ortech Ab | BIORESORBABLE MATERIAL FOR MEDICAL USE |
US5192308A (en) | 1991-04-19 | 1993-03-09 | E. I. Du Pont De Nemours And Company | Vascular prosthesis with an elastomer coating |
US5116937A (en) * | 1991-05-31 | 1992-05-26 | E. I. Du Pont De Nemours And Company | Water-swellable thermoplastic copolyetherester elastomer |
US5166310A (en) | 1991-08-27 | 1992-11-24 | The Dow Chemical Company | Preparation of polyesters with tin catalyst |
JP2598193B2 (en) | 1991-11-21 | 1997-04-09 | 帝人株式会社 | Polyester fiber for industrial use |
JPH05161708A (en) | 1991-12-18 | 1993-06-29 | Terumo Corp | Artificial blood vessel |
US5399665A (en) | 1992-11-05 | 1995-03-21 | Massachusetts Institute Of Technology | Biodegradable polymers for cell transplantation |
US5512600A (en) | 1993-01-15 | 1996-04-30 | Massachusetts Institute Of Technology | Preparation of bonded fiber structures for cell implantation |
US5514378A (en) | 1993-02-01 | 1996-05-07 | Massachusetts Institute Of Technology | Biocompatible polymer membranes and methods of preparation of three dimensional membrane structures |
NL9401703A (en) | 1994-10-14 | 1996-05-01 | Rijksuniversiteit | Chewing gum. |
US5716404A (en) | 1994-12-16 | 1998-02-10 | Massachusetts Institute Of Technology | Breast tissue engineering |
US5688900A (en) | 1995-01-19 | 1997-11-18 | Ethicon, Inc. | Absorbable polyalkylene diglycolates |
US6123727A (en) | 1995-05-01 | 2000-09-26 | Massachusetts Institute Of Technology | Tissue engineered tendons and ligaments |
EP0755971B1 (en) | 1995-07-28 | 2002-03-06 | Tosoh Corporation | Molding resin, composition containing the same, and processes for producing them |
US6095148A (en) | 1995-11-03 | 2000-08-01 | Children's Medical Center Corporation | Neuronal stimulation using electrically conducting polymers |
JP2837126B2 (en) | 1996-01-23 | 1998-12-14 | 三菱重工業株式会社 | Single-facer gluing adjustment method and apparatus |
US5902599A (en) | 1996-02-20 | 1999-05-11 | Massachusetts Institute Of Technology | Biodegradable polymer networks for use in orthopedic and dental applications |
GB9700508D0 (en) | 1997-01-11 | 1997-02-26 | Smith & Nephew | Hydrogels |
ZA984732B (en) | 1997-06-19 | 1999-03-31 | Unichema Chemie Bv | Polymeric compositions |
US5837752A (en) | 1997-07-17 | 1998-11-17 | Massachusetts Institute Of Technology | Semi-interpenetrating polymer networks |
EP0934918A1 (en) | 1997-07-28 | 1999-08-11 | DAICEL CHEMICAL INDUSTRIES, Ltd. | Degradable coat bearing granular compositions for agricultural and horticultural use, biodegradable resin composition, moldings and films of the same, process for the production of films, and degradable trash bags |
US6017566A (en) | 1997-10-20 | 2000-01-25 | Wm. Wrigley Jr. Company | Gum base and chewing gum containing edible polyesters and method for manufacture |
HU222543B1 (en) | 1998-02-23 | 2003-08-28 | Massachusetts Institute Of Technology | Biodegradable shape memory polymers |
US6818018B1 (en) | 1998-08-14 | 2004-11-16 | Incept Llc | In situ polymerizable hydrogels |
EP1139775A4 (en) | 1998-12-17 | 2005-01-05 | Wrigley W M Jun Co | Gum base and chewing gum containing edible polyesters |
US6376742B1 (en) | 1999-02-17 | 2002-04-23 | Richard J. Zdrahala | In vivo tissue engineering with biodegradable polymers |
EP1038538A1 (en) | 1999-03-19 | 2000-09-27 | IsoTis B.V. | Muscle tissue engineering |
WO2001051003A2 (en) | 2000-01-10 | 2001-07-19 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Use of lipid conjugates in the treatment of disease |
US6582717B1 (en) | 2000-04-07 | 2003-06-24 | Massachusetts Institute Of Technology | Drug delivery composition and device |
FI20001696A (en) | 2000-07-21 | 2002-01-22 | Jvs Polymers Oy | Biologically active material |
US7192604B2 (en) * | 2000-12-22 | 2007-03-20 | Ethicon, Inc. | Implantable biodegradable devices for musculoskeletal repair or regeneration |
WO2002067908A1 (en) | 2001-02-26 | 2002-09-06 | Duke University | Novel dendritic polymers and their biomedical uses |
CA2747159A1 (en) * | 2001-05-07 | 2002-11-07 | Queen's University At Kingston | Biodegradable elastomer and method of preparing same |
US7030127B2 (en) | 2001-06-29 | 2006-04-18 | Ethicon, Inc. | Composition and medical devices utilizing bioabsorbable polymeric waxes |
US6869625B2 (en) | 2001-10-09 | 2005-03-22 | Council Of Scientific And Industrial Research | Method of treating diabetes using plant argyrolobium roseum extract, and a process for the isolation of extract from the said plant |
ATE353347T1 (en) | 2001-10-22 | 2007-02-15 | Massachusetts Inst Technology | BIODEGRADABLE POLYMER |
US7722894B2 (en) | 2001-10-22 | 2010-05-25 | Massachusetts Institute Of Technology | Biodegradable polymer |
CA2467836A1 (en) | 2001-11-20 | 2003-09-04 | Duke University | Interfacial biomaterials |
US20040131582A1 (en) | 2002-02-26 | 2004-07-08 | Grinstaff Mark W. | Novel dendritic polymers and their biomedical uses |
US20050019747A1 (en) | 2002-08-07 | 2005-01-27 | Anderson Daniel G. | Nanoliter-scale synthesis of arrayed biomaterials and screening thereof |
WO2005028631A2 (en) | 2003-09-19 | 2005-03-31 | Northwestern University | A novel biodegradable elastomeric scaffold for tissue engineering and light scattering fingerprinting methods for testing the same |
AU2007204617A1 (en) * | 2006-01-12 | 2007-07-19 | Massachusetts Institute Of Technology | Biodegradable elastomers |
US20090011486A1 (en) | 2006-01-12 | 2009-01-08 | Massachusetts Institute Of Technology | Biodegradable Elastomers |
WO2007133807A2 (en) | 2006-05-15 | 2007-11-22 | Massachusetts Institute Of Technology | Polymers for functional particles |
US9415084B2 (en) | 2007-03-14 | 2016-08-16 | Arch Biosurgery, Inc. | Treatment of leaky or damaged tight junctions and enhancing extracellular matrix |
JP5140870B2 (en) | 2007-10-17 | 2013-02-13 | 日本電気株式会社 | Electronic equipment and frame member |
-
2007
- 2007-01-12 AU AU2007204617A patent/AU2007204617A1/en not_active Abandoned
- 2007-01-12 WO PCT/US2007/060532 patent/WO2007082305A2/en active Application Filing
- 2007-01-12 JP JP2008550548A patent/JP2009523864A/en not_active Withdrawn
- 2007-01-12 US US11/623,041 patent/US8143042B2/en active Active
- 2007-01-12 WO PCT/US2007/060529 patent/WO2007082304A2/en active Application Filing
- 2007-01-12 CA CA2636817A patent/CA2636817C/en active Active
- 2007-01-12 EP EP07717803A patent/EP1973493A2/en not_active Withdrawn
-
2012
- 2012-03-23 US US13/428,869 patent/US8691203B2/en active Active
-
2014
- 2014-02-17 US US14/182,095 patent/US10179195B2/en active Active
-
2018
- 2018-11-30 US US16/206,937 patent/US10864303B2/en active Active
-
2020
- 2020-11-13 US US17/097,901 patent/US11458230B2/en active Active
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6444782B1 (en) * | 1999-04-26 | 2002-09-03 | Eastman Chemical Company | Process for making pre-gels for a cross-linked branched polyester |
US20050048121A1 (en) * | 2003-06-04 | 2005-03-03 | Polymerix Corporation | High molecular wegiht polymers, devices and method for making and using same |
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US8691203B2 (en) | 2014-04-08 |
AU2007204617A1 (en) | 2007-07-19 |
US20120269761A1 (en) | 2012-10-25 |
WO2007082304A2 (en) | 2007-07-19 |
US20190091377A1 (en) | 2019-03-28 |
US10864303B2 (en) | 2020-12-15 |
JP2009523864A (en) | 2009-06-25 |
EP1973493A2 (en) | 2008-10-01 |
CA2636817C (en) | 2015-11-03 |
US8143042B2 (en) | 2012-03-27 |
US11458230B2 (en) | 2022-10-04 |
CA2636817A1 (en) | 2007-07-19 |
US20210128794A1 (en) | 2021-05-06 |
WO2007082305A3 (en) | 2007-11-22 |
US20140186312A1 (en) | 2014-07-03 |
US20090047256A1 (en) | 2009-02-19 |
US10179195B2 (en) | 2019-01-15 |
WO2007082305A2 (en) | 2007-07-19 |
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