WO2007112136A3 - Methods and systems for treating injured cardiac tissue - Google Patents

Methods and systems for treating injured cardiac tissue Download PDF

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Publication number
WO2007112136A3
WO2007112136A3 PCT/US2007/060060 US2007060060W WO2007112136A3 WO 2007112136 A3 WO2007112136 A3 WO 2007112136A3 US 2007060060 W US2007060060 W US 2007060060W WO 2007112136 A3 WO2007112136 A3 WO 2007112136A3
Authority
WO
WIPO (PCT)
Prior art keywords
cardiac tissue
systems
methods
treating injured
injured cardiac
Prior art date
Application number
PCT/US2007/060060
Other languages
French (fr)
Other versions
WO2007112136A2 (en
Inventor
Asha Nayak
Original Assignee
Medtronic Vascular Inc
Asha Nayak
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US11/426,219 external-priority patent/US20070014784A1/en
Application filed by Medtronic Vascular Inc, Asha Nayak filed Critical Medtronic Vascular Inc
Priority to EP07756277A priority Critical patent/EP2007404A2/en
Priority to JP2009501617A priority patent/JP2009530412A/en
Publication of WO2007112136A2 publication Critical patent/WO2007112136A2/en
Publication of WO2007112136A3 publication Critical patent/WO2007112136A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/16—Blood plasma; Blood serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/19—Platelets; Megacaryocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/4833—Thrombin (3.4.21.5)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/19—Syringes having more than one chamber, e.g. including a manifold coupling two parallelly aligned syringes through separate channels to a common discharge assembly
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • A61N1/303—Constructional details
    • A61N1/306—Arrangements where at least part of the apparatus is introduced into the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/325—Applying electric currents by contact electrodes alternating or intermittent currents for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body

Abstract

Methods and systems are disclosed for treating cardiac tissue by delivering a platelet composition which induces neovascularization in the cardiac tissue followed by a cell preparation which induces regeneration in the re-vascularized tissue. The platelet composition can additionally contain structural materials and/or bioactive agents.
PCT/US2007/060060 2006-03-23 2007-01-03 Methods and systems for treating injured cardiac tissue WO2007112136A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP07756277A EP2007404A2 (en) 2006-03-23 2007-01-03 Methods and systems for treating injured cardiac tissue
JP2009501617A JP2009530412A (en) 2006-03-23 2007-01-03 Methods and methods for treating damaged heart tissue

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US74368606P 2006-03-23 2006-03-23
US60/743,686 2006-03-23
US11/426,211 2006-06-23
US11/426,219 2006-06-23
US11/426,219 US20070014784A1 (en) 2005-06-23 2006-06-23 Methods and Systems for Treating Injured Cardiac Tissue
US11/426,211 US20070042016A1 (en) 2005-06-23 2006-06-23 Methods and Systems for Treating Injured Cardiac Tissue

Publications (2)

Publication Number Publication Date
WO2007112136A2 WO2007112136A2 (en) 2007-10-04
WO2007112136A3 true WO2007112136A3 (en) 2007-11-29

Family

ID=56290896

Family Applications (2)

Application Number Title Priority Date Filing Date
PCT/US2007/060059 WO2007112135A2 (en) 2006-03-23 2007-01-03 Methods and systems for treating injured cardiac tissue
PCT/US2007/060060 WO2007112136A2 (en) 2006-03-23 2007-01-03 Methods and systems for treating injured cardiac tissue

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PCT/US2007/060059 WO2007112135A2 (en) 2006-03-23 2007-01-03 Methods and systems for treating injured cardiac tissue

Country Status (3)

Country Link
EP (2) EP2007403A2 (en)
JP (2) JP2009530411A (en)
WO (2) WO2007112135A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6811777B2 (en) 2002-04-13 2004-11-02 Allan Mishra Compositions and minimally invasive methods for treating incomplete connective tissue repair
US8057426B2 (en) 2007-01-03 2011-11-15 Medtronic Vascular, Inc. Devices and methods for injection of multiple-component therapies
WO2010042658A1 (en) 2008-10-07 2010-04-15 Bioparadox, Llc Use of platelet rich plasma composition in the treatment of cardiac conduction abnormalities
EP2337617A4 (en) * 2008-10-09 2013-06-12 Bioparadox Llc Platelet rich plasma formulations for cardiac treatments
IL210162A0 (en) 2010-12-21 2011-03-31 Omrix Biopharmaceuticals Viral inactivated platelet extract, use and preparation thereof
US20140356893A1 (en) 2013-06-04 2014-12-04 Allan Mishra Compositions and methods for using platelet-rich plasma for drug discovery, cell nuclear reprogramming, proliferation or differentiation

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030007957A1 (en) * 2001-07-03 2003-01-09 Calvin Britton Novel wound healing composition not containing bovine-derived activating reagents
WO2004084825A2 (en) * 2003-03-24 2004-10-07 Harch Paul M D Wound healing composition derived from low platelet concentration plasma
US20050209564A1 (en) * 2001-01-13 2005-09-22 Medtronic, Inc. Devices and methods for interstitial injection of biologic agents into tissue
US20060041243A1 (en) * 2001-01-13 2006-02-23 Medtronic, Inc. Devices and methods for interstitial injection of biologic agents into tissue

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050209564A1 (en) * 2001-01-13 2005-09-22 Medtronic, Inc. Devices and methods for interstitial injection of biologic agents into tissue
US20060041243A1 (en) * 2001-01-13 2006-02-23 Medtronic, Inc. Devices and methods for interstitial injection of biologic agents into tissue
US20030007957A1 (en) * 2001-07-03 2003-01-09 Calvin Britton Novel wound healing composition not containing bovine-derived activating reagents
WO2004084825A2 (en) * 2003-03-24 2004-10-07 Harch Paul M D Wound healing composition derived from low platelet concentration plasma

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
ANITUA E ET AL: "Autologous preparations rich in growth factors promote proliferation and induce VEGF and HGF production by human tendon cells in culture", JOURNAL OF ORTHOPAEDIC RESEARCH, THE JOURNAL OF BONE AND JOINT SURGERY, INC.,, US, vol. 23, no. 2, March 2005 (2005-03-01), pages 281 - 286, XP004763650, ISSN: 0736-0266 *
KUHN D F M ET AL: "Novel therapeutic options due to autologous blood components - Exemplified by autologous platelet gel", TRANSFUSION MEDICINE AND HEMOTHERAPY, vol. 33, no. 4, August 2006 (2006-08-01), pages 307 - 313, XP008083237, ISSN: 1660-3796 *
MOGAN C ET AL: "Rationale of platelet gel to augment adaptive remodeling of the injured heart", JOURNAL OF EXTRA-CORPOREAL TECHNOLOGY 2004 UNITED STATES, vol. 36, no. 2, 2004, pages 191 - 196, XP008083236, ISSN: 0022-1058 *

Also Published As

Publication number Publication date
EP2007403A2 (en) 2008-12-31
WO2007112136A2 (en) 2007-10-04
JP2009530412A (en) 2009-08-27
WO2007112135A3 (en) 2007-11-22
WO2007112135A2 (en) 2007-10-04
EP2007404A2 (en) 2008-12-31
JP2009530411A (en) 2009-08-27

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