WO2007120381A3 - Analyte sensor - Google Patents

Analyte sensor Download PDF

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Publication number
WO2007120381A3
WO2007120381A3 PCT/US2007/003881 US2007003881W WO2007120381A3 WO 2007120381 A3 WO2007120381 A3 WO 2007120381A3 US 2007003881 W US2007003881 W US 2007003881W WO 2007120381 A3 WO2007120381 A3 WO 2007120381A3
Authority
WO
WIPO (PCT)
Prior art keywords
membranes
devices
hydrophilic polymer
polymer blend
silicone
Prior art date
Application number
PCT/US2007/003881
Other languages
French (fr)
Other versions
WO2007120381A2 (en
Inventor
Robert Boock
Monica Rixman
James H Brauker
James R Petisce
Peter Simpson
Mark Brister
Mark A Tapsak
Victoria Carr-Brendel
Original Assignee
Dexcom Inc
Robert Boock
Monica Rixman
James H Brauker
James R Petisce
Peter Simpson
Mark Brister
Mark A Tapsak
Victoria Carr-Brendel
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US11/404,417 external-priority patent/US7613491B2/en
Priority claimed from US11/439,630 external-priority patent/US10022078B2/en
Application filed by Dexcom Inc, Robert Boock, Monica Rixman, James H Brauker, James R Petisce, Peter Simpson, Mark Brister, Mark A Tapsak, Victoria Carr-Brendel filed Critical Dexcom Inc
Publication of WO2007120381A2 publication Critical patent/WO2007120381A2/en
Publication of WO2007120381A3 publication Critical patent/WO2007120381A3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1486Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using enzyme electrodes, e.g. with immobilised oxidase
    • A61B5/14865Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using enzyme electrodes, e.g. with immobilised oxidase invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0002Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
    • A61B5/0031Implanted circuitry
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/41Detecting, measuring or recording for evaluating the immune or lymphatic systems
    • A61B5/414Evaluating particular organs or parts of the immune or lymphatic systems
    • A61B5/418Evaluating particular organs or parts of the immune or lymphatic systems lymph vessels, ducts or nodes

Abstract

The present invention relates generally to membranes utilized with implantable devices, such as devices for the detection of analyte concentrations in a biological sample. More particularly, the invention relates to novel silicone-hydrophilic polymer blend membranes, and to devices and implantable devices including these membranes, for example, a continuous analyte needle-type sensor (34) including a reference electrode (30) helically wound around the working electrode (38), and covered by a membrane system (32) including a silicone-hydrophilic polymer blend membrane.
PCT/US2007/003881 2006-04-14 2007-02-14 Analyte sensor WO2007120381A2 (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US11/404,417 US7613491B2 (en) 2002-05-22 2006-04-14 Silicone based membranes for use in implantable glucose sensors
US11/404,417 2006-04-14
US11/439,630 2006-05-23
US11/439,630 US10022078B2 (en) 2004-07-13 2006-05-23 Analyte sensor
US11/503,367 US9986942B2 (en) 2004-07-13 2006-08-10 Analyte sensor
US11/503,367 2006-08-10

Publications (2)

Publication Number Publication Date
WO2007120381A2 WO2007120381A2 (en) 2007-10-25
WO2007120381A3 true WO2007120381A3 (en) 2008-03-27

Family

ID=38610023

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/003881 WO2007120381A2 (en) 2006-04-14 2007-02-14 Analyte sensor

Country Status (2)

Country Link
US (1) US7828728B2 (en)
WO (1) WO2007120381A2 (en)

Families Citing this family (156)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8527026B2 (en) 1997-03-04 2013-09-03 Dexcom, Inc. Device and method for determining analyte levels
US6001067A (en) 1997-03-04 1999-12-14 Shults; Mark C. Device and method for determining analyte levels
US8346337B2 (en) 1998-04-30 2013-01-01 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US6175752B1 (en) 1998-04-30 2001-01-16 Therasense, Inc. Analyte monitoring device and methods of use
US8480580B2 (en) 1998-04-30 2013-07-09 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8688188B2 (en) 1998-04-30 2014-04-01 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US6949816B2 (en) 2003-04-21 2005-09-27 Motorola, Inc. Semiconductor component having first surface area for electrically coupling to a semiconductor chip and second surface area for electrically coupling to a substrate, and method of manufacturing same
US8974386B2 (en) 1998-04-30 2015-03-10 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8465425B2 (en) 1998-04-30 2013-06-18 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US9066695B2 (en) 1998-04-30 2015-06-30 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US6560471B1 (en) 2001-01-02 2003-05-06 Therasense, Inc. Analyte monitoring device and methods of use
US7041468B2 (en) 2001-04-02 2006-05-09 Therasense, Inc. Blood glucose tracking apparatus and methods
US20030032874A1 (en) 2001-07-27 2003-02-13 Dexcom, Inc. Sensor head for use with implantable devices
US7613491B2 (en) 2002-05-22 2009-11-03 Dexcom, Inc. Silicone based membranes for use in implantable glucose sensors
US8364229B2 (en) 2003-07-25 2013-01-29 Dexcom, Inc. Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise
US7828728B2 (en) 2003-07-25 2010-11-09 Dexcom, Inc. Analyte sensor
JP4708342B2 (en) 2003-07-25 2011-06-22 デックスコム・インコーポレーテッド Oxygen augmentation membrane system for use in implantable devices
US9763609B2 (en) 2003-07-25 2017-09-19 Dexcom, Inc. Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise
US7774145B2 (en) 2003-08-01 2010-08-10 Dexcom, Inc. Transcutaneous analyte sensor
US8160669B2 (en) 2003-08-01 2012-04-17 Dexcom, Inc. Transcutaneous analyte sensor
US20190357827A1 (en) 2003-08-01 2019-11-28 Dexcom, Inc. Analyte sensor
US7920906B2 (en) 2005-03-10 2011-04-05 Dexcom, Inc. System and methods for processing analyte sensor data for sensor calibration
CN100479750C (en) * 2003-09-02 2009-04-22 早出广司 Glucose sensor and glucose level measuring apparatus
US9247900B2 (en) 2004-07-13 2016-02-02 Dexcom, Inc. Analyte sensor
US8532730B2 (en) 2006-10-04 2013-09-10 Dexcom, Inc. Analyte sensor
US8277713B2 (en) 2004-05-03 2012-10-02 Dexcom, Inc. Implantable analyte sensor
US7946984B2 (en) 2004-07-13 2011-05-24 Dexcom, Inc. Transcutaneous analyte sensor
EP1669747A1 (en) * 2004-12-09 2006-06-14 ETH Zürich Formation of highly porous gas-sensing layers by deposition of nanoparticles produced by flame spray pyrolysis
US7545272B2 (en) 2005-02-08 2009-06-09 Therasense, Inc. RF tag on test strips, test strip vials and boxes
US8744546B2 (en) 2005-05-05 2014-06-03 Dexcom, Inc. Cellulosic-based resistance domain for an analyte sensor
US7885698B2 (en) 2006-02-28 2011-02-08 Abbott Diabetes Care Inc. Method and system for providing continuous calibration of implantable analyte sensors
WO2007143225A2 (en) 2006-06-07 2007-12-13 Abbott Diabetes Care, Inc. Analyte monitoring system and method
SI1972275T1 (en) * 2007-03-20 2016-02-29 F. Hoffmann-La Roche Ag System for in vivo measurement of an analyte concentration
CA2681412A1 (en) 2007-03-26 2008-10-02 Dexcom, Inc. Analyte sensor
US20200037874A1 (en) 2007-05-18 2020-02-06 Dexcom, Inc. Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise
US8263104B2 (en) * 2007-06-08 2012-09-11 Northwestern University Polymer nanofilm coatings
US9005263B2 (en) 2007-08-17 2015-04-14 The Invention Science Fund I, Llc System, devices, and methods including actively-controllable sterilizing excitation delivery implants
US8706211B2 (en) * 2007-08-17 2014-04-22 The Invention Science Fund I, Llc Systems, devices, and methods including catheters having self-cleaning surfaces
US8753304B2 (en) 2007-08-17 2014-06-17 The Invention Science Fund I, Llc Systems, devices, and methods including catheters having acoustically actuatable waveguide components for delivering a sterilizing stimulus to a region proximate a surface of the catheter
US8734718B2 (en) 2007-08-17 2014-05-27 The Invention Science Fund I, Llc Systems, devices, and methods including catheters having an actively controllable therapeutic agent delivery component
US8460229B2 (en) 2007-08-17 2013-06-11 The Invention Science Fund I, Llc Systems, devices, and methods including catheters having components that are actively controllable between transmissive and reflective states
US8647292B2 (en) 2007-08-17 2014-02-11 The Invention Science Fund I, Llc Systems, devices, and methods including catheters having components that are actively controllable between two or more wettability states
US8162924B2 (en) 2007-08-17 2012-04-24 The Invention Science Fund I, Llc System, devices, and methods including actively-controllable superoxide water generating systems
US8366652B2 (en) * 2007-08-17 2013-02-05 The Invention Science Fund I, Llc Systems, devices, and methods including infection-fighting and monitoring shunts
US8702640B2 (en) 2007-08-17 2014-04-22 The Invention Science Fund I, Llc System, devices, and methods including catheters configured to monitor and inhibit biofilm formation
US9452258B2 (en) 2007-10-09 2016-09-27 Dexcom, Inc. Integrated insulin delivery system with continuous glucose sensor
CA2702799A1 (en) 2007-10-25 2009-04-30 Dexcom, Inc. Systems and methods for processing sensor data
WO2009105709A1 (en) 2008-02-21 2009-08-27 Dexcom, Inc. Systems and methods for processing, transmitting and displaying sensor data
US8583204B2 (en) 2008-03-28 2013-11-12 Dexcom, Inc. Polymer membranes for continuous analyte sensors
US8682408B2 (en) 2008-03-28 2014-03-25 Dexcom, Inc. Polymer membranes for continuous analyte sensors
CN102047101A (en) 2008-03-28 2011-05-04 德克斯康公司 Polymer membranes for continuous analyte sensors
US11730407B2 (en) 2008-03-28 2023-08-22 Dexcom, Inc. Polymer membranes for continuous analyte sensors
US10799593B2 (en) 2008-06-09 2020-10-13 Northwestern University Nanodiamond particle complexes
WO2009152167A2 (en) * 2008-06-09 2009-12-17 Northwestern University Delivery of therapeutics
US9682173B2 (en) * 2008-06-11 2017-06-20 The Children's Mercy Hospital Solutions for tissue engineering and methods of use
US8900431B2 (en) 2008-08-27 2014-12-02 Edwards Lifesciences Corporation Analyte sensor
EP2326944B1 (en) 2008-09-19 2020-08-19 Dexcom, Inc. Particle-containing membrane and particulate electrode for analyte sensors
US20110295088A1 (en) 2008-12-04 2011-12-01 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Systems, devices, and methods including implantable devices with anti-microbial properties
US8585627B2 (en) 2008-12-04 2013-11-19 The Invention Science Fund I, Llc Systems, devices, and methods including catheters configured to monitor biofilm formation having biofilm spectral information configured as a data structure
US20100160755A1 (en) * 2008-12-24 2010-06-24 Edwards Lifesciences Corporation Polyelectrolytes as Sublayers on Electrochemical Sensors
US20100213057A1 (en) 2009-02-26 2010-08-26 Benjamin Feldman Self-Powered Analyte Sensor
US8831743B2 (en) 2009-03-04 2014-09-09 Imricor Medical Systems, Inc. MRI compatible electrode circuit
US8855788B2 (en) 2009-03-04 2014-10-07 Imricor Medical Systems, Inc. MRI compatible electrode circuit
CA2754045C (en) 2009-03-04 2021-04-06 Imricor Medical Systems, Inc. Mri compatible electrode circuit
US8761899B2 (en) 2009-03-04 2014-06-24 Imricor Medical Systems, Inc. MRI compatible conductive wires
US8843213B2 (en) 2009-03-04 2014-09-23 Imricor Medical Systems, Inc. MRI compatible co-radially wound lead assembly
AU2013206743B2 (en) * 2009-03-04 2014-10-30 Imricor Medical Systems, Inc. MRI compatible electrode circuit
US8805540B2 (en) 2009-03-04 2014-08-12 Imricor Medical Systems, Inc. MRI compatible cable
US9216388B2 (en) * 2009-06-23 2015-12-22 Ge Healthcare Bio-Sciences Ab Simulator device
US20110024043A1 (en) 2009-07-02 2011-02-03 Dexcom, Inc. Continuous analyte sensors and methods of making same
US9351677B2 (en) 2009-07-02 2016-05-31 Dexcom, Inc. Analyte sensor with increased reference capacity
EP2482724A2 (en) 2009-09-30 2012-08-08 Dexcom, Inc. Transcutaneous analyte sensor
US9029168B2 (en) * 2010-06-28 2015-05-12 The Trustees Of Princeton University Use and making of biosensors utilizing antimicrobial peptides for highly sensitive biological monitoring
WO2012019083A2 (en) * 2010-08-06 2012-02-09 Microchips, Inc. Biosensor membrane composition, biosensor, and methods for making same
EP4333325A2 (en) 2010-09-29 2024-03-06 Dexcom, Inc. Advanced continuous analyte monitoring system
US8844007B2 (en) 2011-04-08 2014-09-23 Dexcom, Inc. Systems and methods for processing and transmitting sensor data
DK3575796T3 (en) 2011-04-15 2021-01-18 Dexcom Inc ADVANCED ANALYZE SENSOR CALIBRATION AND ERROR DETECTION
US8870769B2 (en) 2011-05-23 2014-10-28 Covidien Lp Inter dialytic monitoring device
LU91841B1 (en) * 2011-07-15 2013-01-16 Ct De Rech Public Gabriel Lippmann Method for forming gas sensing layers
US20130035865A1 (en) 2011-08-05 2013-02-07 Dexcom, Inc. Systems and methods for detecting glucose level data patterns
US9101301B2 (en) 2011-08-15 2015-08-11 The University Of Connecticut Control of biofouling in implantable biosensors
WO2013032940A1 (en) * 2011-08-26 2013-03-07 Dexcom, Inc. Polymer membranes for continuous analyte sensors
EP3092949B1 (en) 2011-09-23 2020-12-09 Dexcom, Inc. Systems and methods for processing and transmitting sensor data
US8556883B2 (en) * 2012-02-27 2013-10-15 Rafic Saleh Medical surgical navigation sensor mounting system
US10278629B2 (en) 2012-03-12 2019-05-07 University Of South Florida Implantable biocompatible SiC sensors
US9615779B2 (en) 2012-04-04 2017-04-11 Dexcom, Inc. Transcutaneous analyte sensors, applicators therefor, and associated methods
US20130321425A1 (en) 2012-06-05 2013-12-05 Dexcom, Inc. Reporting modules
US10881339B2 (en) 2012-06-29 2021-01-05 Dexcom, Inc. Use of sensor redundancy to detect sensor failures
US10598627B2 (en) 2012-06-29 2020-03-24 Dexcom, Inc. Devices, systems, and methods to compensate for effects of temperature on implantable sensors
US20140012117A1 (en) 2012-07-09 2014-01-09 Dexcom, Inc. Systems and methods for leveraging smartphone features in continuous glucose monitoring
US9788765B2 (en) 2012-09-28 2017-10-17 Dexcom, Inc. Zwitterion surface modifications for continuous sensors
US20140129151A1 (en) 2012-11-07 2014-05-08 Dexcom, Inc. Systems and methods for managing glycemic variability
US9585563B2 (en) 2012-12-31 2017-03-07 Dexcom, Inc. Remote monitoring of analyte measurements
US9730620B2 (en) 2012-12-31 2017-08-15 Dexcom, Inc. Remote monitoring of analyte measurements
US9445445B2 (en) 2013-03-14 2016-09-13 Dexcom, Inc. Systems and methods for processing and transmitting sensor data
US10335075B2 (en) 2013-03-14 2019-07-02 Dexcom, Inc. Advanced calibration for analyte sensors
EP4220654A1 (en) 2013-03-14 2023-08-02 Dexcom, Inc. Systems and methods for processing and transmitting sensor data
US9737250B2 (en) 2013-03-15 2017-08-22 Dexcom, Inc. Membrane for continuous analyte sensors
EP4050617A1 (en) 2013-11-07 2022-08-31 Dexcom, Inc. Systems and methods for transmitting and continuous monitoring of analyte values
EP4309570A1 (en) 2013-12-16 2024-01-24 DexCom, Inc. Systems and methods for monitoring and managing life of a battery in an analyte sensor system worn by a user
US10595759B2 (en) 2014-01-21 2020-03-24 The Regents Of The University Of California Salivary biosensors and biofuel cells
FI3128902T3 (en) 2014-04-10 2023-11-16 Dexcom Inc Sensor for continuous analyte monitoring
AU2015271133B2 (en) 2014-06-06 2018-07-05 Dexcom, Inc. Fault discrimination and responsive processing based on data and context
US10159943B2 (en) * 2014-07-24 2018-12-25 Toray Industries, Inc. Carbon membrane for fluid separation, fluid separation membrane module, and method for producing carbon membrane for fluid separation
AU2015328459A1 (en) 2014-10-06 2017-04-20 Dexcom, Inc. System and method for data analytics and visualization
US10864367B2 (en) 2015-02-24 2020-12-15 Elira, Inc. Methods for using an electrical dermal patch in a manner that reduces adverse patient reactions
US10765863B2 (en) 2015-02-24 2020-09-08 Elira, Inc. Systems and methods for using a transcutaneous electrical stimulation device to deliver titrated therapy
US9956393B2 (en) 2015-02-24 2018-05-01 Elira, Inc. Systems for increasing a delay in the gastric emptying time for a patient using a transcutaneous electro-dermal patch
US10376145B2 (en) 2015-02-24 2019-08-13 Elira, Inc. Systems and methods for enabling a patient to achieve a weight loss objective using an electrical dermal patch
US10335302B2 (en) 2015-02-24 2019-07-02 Elira, Inc. Systems and methods for using transcutaneous electrical stimulation to enable dietary interventions
EP3261712B1 (en) 2015-02-24 2024-04-03 Elira, Inc. System for enabling appetite modulation and/or improving dietary compliance using an electro-dermal patch
US10707526B2 (en) 2015-03-27 2020-07-07 New Dominion Enterprises Inc. All-inorganic solvents for electrolytes
CN104965073A (en) * 2015-05-25 2015-10-07 东华大学 Electrochemical nucleic acid aptamer biosensor for detecting ibuprofen, and production method thereof
CN104931555B (en) * 2015-06-23 2018-11-20 好来化工(中山)有限公司 The device of pH value and preparation method thereof for detecting saliva
ES2911676T3 (en) 2015-10-21 2022-05-20 Dexcom Inc Transcutaneous analyte sensors, applicators therefor, and associated methods
EP3397140A4 (en) 2015-12-28 2019-08-21 Dexcom, Inc. Systems and methods for remote and host monitoring communications
EP3397141B1 (en) 2015-12-28 2022-01-26 Dexcom, Inc. Intelligent wireless communications for continuous analyte monitoring
CA3002482C (en) 2015-12-30 2021-06-08 Dexcom, Inc. System and method for factory calibration or reduced calibration of an indwelling sensor based on sensitivity profile and baseline model of sensors
WO2017117472A1 (en) 2015-12-30 2017-07-06 Dexcom, Inc. Biointerface layer for analyte sensors
JP7059194B2 (en) 2016-03-30 2022-04-25 デックスコム・インコーポレーテッド System for sample monitoring system
CA3133253A1 (en) 2016-03-31 2017-10-05 Dexcom, Inc. Systems and methods for display device and sensor electronics unit communication
CA3017255C (en) 2016-05-02 2023-10-24 Dexcom, Inc. System and method for providing alerts optimized for a user
EP4277322A3 (en) 2016-07-20 2024-01-24 Dexcom, Inc. System and method for wireless communication of glucose data
WO2018031803A1 (en) 2016-08-12 2018-02-15 Dexcom, Inc. Systems and methods for health data visualization and user support tools for continuous glucose monitoring
EP3510533B1 (en) 2016-09-09 2022-07-27 Dexcom, Inc. Method for enabling health care provider set up of a bolus calculator
US10707531B1 (en) 2016-09-27 2020-07-07 New Dominion Enterprises Inc. All-inorganic solvents for electrolytes
CA3032202A1 (en) 2016-10-18 2018-04-26 Dexcom, Inc. System and method for communication of analyte data
US11032855B2 (en) 2016-10-18 2021-06-08 Dexcom, Inc. System and method for communication of analyte data
EP3500854A4 (en) 2016-11-09 2020-01-29 Dexcom, Inc. Systems and methods for technical support of continuous analyte monitoring and sensor systems
WO2023034934A1 (en) 2021-09-03 2023-03-09 Dexcom, Inc. Systems and methods for technical support of continuous analyte monitoring and sensor systems
AU2017388066B9 (en) 2016-12-27 2021-04-01 Dexcom, Inc. Systems and methods for patient monitoring using an HCP - specific device
US11224878B2 (en) * 2017-05-05 2022-01-18 Quantum-Si Incorporated Substrates having modified surface reactivity and antifouling properties in biological reactions
KR20200067124A (en) 2017-06-23 2020-06-11 덱스콤, 인크. Transdermal analysis sensor, applicator for this, and associated method
US11331022B2 (en) 2017-10-24 2022-05-17 Dexcom, Inc. Pre-connected analyte sensors
US20190120785A1 (en) 2017-10-24 2019-04-25 Dexcom, Inc. Pre-connected analyte sensors
DE202018006861U1 (en) 2017-10-30 2023-11-22 Dexcom, Inc. Diabetes management partner interface for wireless communication of analyte data
JP2021511094A (en) 2018-01-23 2021-05-06 デックスコム・インコーポレーテッド Systems, devices and methods for compensating for temperature effects on sensors
AU2019217879B2 (en) 2018-02-09 2023-12-21 Dexcom, Inc. System and method for decision support
US11576595B2 (en) 2018-04-06 2023-02-14 Zense-Life Inc. Enhanced sensor for a continuous biological monitor
CN112292078A (en) 2018-04-06 2021-01-29 赞思健康科技有限公司 Continuous glucose monitoring device
EP3787507A4 (en) 2018-05-03 2022-01-12 Dexcom, Inc. Systems and method for activating analyte sensor electronics
US11642048B2 (en) 2018-05-04 2023-05-09 Dexcom, Inc. Systems and methods relating to an analyte sensor system having a battery located within a disposable base
US11457843B2 (en) 2018-08-03 2022-10-04 Dexcom, Inc. Systems and methods for communication with analyte sensor electronics
AU2019414451A1 (en) 2018-12-28 2021-06-17 Dexcom, Inc. Analyte sensor break-in mitigation
AU2020284312A1 (en) 2019-05-29 2021-12-23 Dexcom, Inc. System and method for wireless communication of analyte data
CA3147845A1 (en) 2019-07-16 2021-01-21 Dexcom, Inc. Analyte sensor electrode arrangements
US20210076993A1 (en) * 2019-09-18 2021-03-18 Medtronic Minimed, Inc. Immunosuppressant releasing coatings
KR20220079943A (en) 2019-10-11 2022-06-14 퀀텀-에스아이 인코포레이티드 Surface modification in vapor phase
EP4225140A1 (en) * 2020-10-05 2023-08-16 Zense-Life Inc. In-vivo glucose specific sensor
WO2022174213A1 (en) 2021-02-11 2022-08-18 Dexcom, Inc. Network physical layer configurations for ambulatory physiological parameter monitoring and therapeutic intervention systems
AU2022249389A1 (en) 2021-04-02 2023-11-02 Dexcom, Inc. Personalized modeling of blood glucose concentration impacted by individualized sensor characteristics and individualized physiological characteristics
WO2023107107A1 (en) 2021-12-08 2023-06-15 Liang Wang Systems, devices, and methods to compensate for temperature effects on sensors
US20230190151A1 (en) 2021-12-17 2023-06-22 Dexcom, Inc. Analyte sensor deployment testing
WO2023147389A1 (en) 2022-01-27 2023-08-03 Dexcom, Inc. System and method for activating an analyte monitoring system
WO2023219847A1 (en) 2022-05-13 2023-11-16 Dexcom, Inc. Cost-effective therapy recommendations
WO2024050124A1 (en) 2022-09-02 2024-03-07 Dexcom, Inc. Devices and methods for measuring a concentration of a target analyte in a biological fluid in vivo

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050054909A1 (en) * 2003-07-25 2005-03-10 James Petisce Oxygen enhancing membrane systems for implantable devices
US20050090607A1 (en) * 2003-10-28 2005-04-28 Dexcom, Inc. Silicone composition for biocompatible membrane
WO2005044088A2 (en) * 2003-11-03 2005-05-19 Children's Medical Center Corporation Continuous analyte monitor and method of using same
US6973706B2 (en) * 1998-03-04 2005-12-13 Therasense, Inc. Method of making a transcutaneous electrochemical sensor
US20060036143A1 (en) * 2004-07-13 2006-02-16 Dexcom, Inc. Transcutaneous analyte sensor

Family Cites Families (468)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2830020A (en) * 1956-10-01 1958-04-08 American Cyanamid Co Lubricating oils thickened with metal salts of cyanuric acid
US3220960A (en) * 1960-12-21 1965-11-30 Wichterle Otto Cross-linked hydrophilic polymers and articles made therefrom
US3562352A (en) * 1968-09-06 1971-02-09 Avco Corp Polysiloxane-polyurethane block copolymers
US3607329A (en) 1969-04-22 1971-09-21 Us Interior Cellulose acetate butyrate semipermeable membranes and their production
US3746588A (en) 1971-03-29 1973-07-17 Aerojet General Co Sterilization of nitroparaffin-amine explosives
US3943918A (en) 1971-12-02 1976-03-16 Tel-Pac, Inc. Disposable physiological telemetric device
GB1442303A (en) 1972-09-08 1976-07-14 Radiometer As Cell for electro-chemical analysis
US4267145A (en) * 1974-01-03 1981-05-12 E. I. Du Pont De Nemours And Company Process for preparing cold water-soluble films from PVA by melt extrusion
US3898984A (en) 1974-02-04 1975-08-12 Us Navy Ambulatory patient monitoring system
US3979274A (en) 1975-09-24 1976-09-07 The Yellow Springs Instrument Company, Inc. Membrane for enzyme electrodes
US4040908A (en) 1976-03-12 1977-08-09 Children's Hospital Medical Center Polarographic analysis of cholesterol and other macromolecular substances
US4136250A (en) * 1977-07-20 1979-01-23 Ciba-Geigy Corporation Polysiloxane hydrogels
DE2820474C2 (en) * 1978-05-10 1983-11-10 Fresenius AG, 6380 Bad Homburg Electrochemical probe
US4292423A (en) 1979-04-19 1981-09-29 Wacker-Chemie Gmbh Process for the preparation of organopolysiloxanes
US4253469A (en) 1979-04-20 1981-03-03 The Narda Microwave Corporation Implantable temperature probe
DE2932761A1 (en) 1979-08-13 1981-02-26 Akzo Gmbh POLYCARBONATE-POLYAETHER-COPOLYMER MEMBRANE
US4260725A (en) 1979-12-10 1981-04-07 Bausch & Lomb Incorporated Hydrophilic contact lens made from polysiloxanes which are thermally bonded to polymerizable groups and which contain hydrophilic sidechains
US4403984A (en) 1979-12-28 1983-09-13 Biotek, Inc. System for demand-based adminstration of insulin
US4686137A (en) 1980-02-29 1987-08-11 Thoratec Laboratories Corp. Moisture vapor permeable materials
US4861830A (en) 1980-02-29 1989-08-29 Th. Goldschmidt Ag Polymer systems suitable for blood-contacting surfaces of a biomedical device, and methods for forming
US5120813A (en) 1980-02-29 1992-06-09 Th. Goldschmidt Ag Moisture vapor permeable materials
US4442841A (en) 1981-04-30 1984-04-17 Mitsubishi Rayon Company Limited Electrode for living bodies
DE3278334D1 (en) 1981-10-23 1988-05-19 Genetics Int Inc Sensor for components of a liquid mixture
US4431004A (en) * 1981-10-27 1984-02-14 Bessman Samuel P Implantable glucose sensor
US4418148A (en) 1981-11-05 1983-11-29 Miles Laboratories, Inc. Multilayer enzyme electrode membrane
US4415666A (en) 1981-11-05 1983-11-15 Miles Laboratories, Inc. Enzyme electrode membrane
US4454295A (en) 1981-11-16 1984-06-12 Uco Optics, Inc. Cured cellulose ester, method of curing same, and use thereof
JPS5886172A (en) 1981-11-18 1983-05-23 テルモ株式会社 Medical substance moving apparatus
US4494950A (en) * 1982-01-19 1985-01-22 The Johns Hopkins University Plural module medication delivery system
US4482666A (en) * 1982-03-12 1984-11-13 Apace Research Limited Emulsions of liquid hydrocarbons with water and/or alcohols
US4493714A (en) * 1982-05-06 1985-01-15 Teijin Limited Ultrathin film, process for production thereof, and use thereof for concentrating a specified gas in a gaseous mixture
EP0098592A3 (en) 1982-07-06 1985-08-21 Fujisawa Pharmaceutical Co., Ltd. Portable artificial pancreas
CA1226036A (en) 1983-05-05 1987-08-25 Irving J. Higgins Analytical equipment and sensor electrodes therefor
CA1219040A (en) 1983-05-05 1987-03-10 Elliot V. Plotkin Measurement of enzyme-catalysed reactions
US4484987A (en) 1983-05-19 1984-11-27 The Regents Of The University Of California Method and membrane applicable to implantable sensor
US4650547A (en) 1983-05-19 1987-03-17 The Regents Of The University Of California Method and membrane applicable to implantable sensor
US4554927A (en) 1983-08-30 1985-11-26 Thermometrics Inc. Pressure and temperature sensor
GB2149918A (en) 1983-11-03 1985-06-19 John Anderson Sudden infant death syndrome monitor
JPS60146219A (en) 1984-01-11 1985-08-01 Toray Ind Inc Contact lens
US4739380A (en) 1984-01-19 1988-04-19 Integrated Ionics, Inc. Integrated ambient sensing devices and methods of manufacture
US4527999A (en) 1984-03-23 1985-07-09 Abcor, Inc. Separation membrane and method of preparing and using same
US4644046A (en) * 1984-06-20 1987-02-17 Teijin Limited Ultrathin film, process for production thereof, and use thereof for concentrating a specific gas from a gas mixture
CA1258496A (en) 1984-07-30 1989-08-15 Teruyoshi Uchida Insulated noble metal wire and porous membrane as po.sub.2 bioelectrode
US5030333A (en) 1984-09-13 1991-07-09 Children's Hospital Medical Center Polarographic method for measuring both analyte and oxygen with the same detecting electrode of an electroenzymatic sensor
US5171689A (en) 1984-11-08 1992-12-15 Matsushita Electric Industrial Co., Ltd. Solid state bio-sensor
US4602922A (en) 1984-11-09 1986-07-29 Research Foundation Of State University Of New York Method of making membranes for gas separation and the composite membranes
US4963595A (en) 1985-01-04 1990-10-16 Thoratec Laboratories Corporation Polysiloxane-polylactone block copolymers
US5235003A (en) 1985-01-04 1993-08-10 Thoratec Laboratories Corporation Polysiloxane-polylactone block copolymers
GB8514176D0 (en) 1985-06-05 1985-07-10 Ici Plc Membrane
US4671288A (en) 1985-06-13 1987-06-09 The Regents Of The University Of California Electrochemical cell sensor for continuous short-term use in tissues and blood
US4938860A (en) 1985-06-28 1990-07-03 Miles Inc. Electrode for electrochemical sensors
US4680268A (en) 1985-09-18 1987-07-14 Children's Hospital Medical Center Implantable gas-containing biosensor and method for measuring an analyte such as glucose
US4890620A (en) * 1985-09-20 1990-01-02 The Regents Of The University Of California Two-dimensional diffusion glucose substrate sensing electrode
US4689309A (en) 1985-09-30 1987-08-25 Miles Laboratories, Inc. Test device, method of manufacturing same and method of determining a component in a sample
US4647643A (en) 1985-11-08 1987-03-03 Becton, Dickinson And Company Soft non-blocking polyurethanes
US4684538A (en) 1986-02-21 1987-08-04 Loctite Corporation Polysiloxane urethane compounds and adhesive compositions, and method of making and using the same
JPS62225513A (en) * 1986-03-26 1987-10-03 Shin Etsu Chem Co Ltd Block-graft copolymer and production thereof
US4685463A (en) 1986-04-03 1987-08-11 Williams R Bruce Device for continuous in vivo measurement of blood glucose concentrations
US4994167A (en) * 1986-04-15 1991-02-19 Markwell Medical Institute, Inc. Biological fluid measuring device
US4757022A (en) 1986-04-15 1988-07-12 Markwell Medical Institute, Inc. Biological fluid measuring device
US4909908A (en) 1986-04-24 1990-03-20 Pepi Ross Electrochemical cncentration detector method
US4795542A (en) * 1986-04-24 1989-01-03 St. Jude Medical, Inc. Electrochemical concentration detector device
US4703756A (en) 1986-05-06 1987-11-03 The Regents Of The University Of California Complete glucose monitoring system with an implantable, telemetered sensor module
US4731726A (en) 1986-05-19 1988-03-15 Healthware Corporation Patient-operated glucose monitor and diabetes management system
GB8612861D0 (en) 1986-05-27 1986-07-02 Cambridge Life Sciences Immobilised enzyme biosensors
US4763658A (en) 1986-06-04 1988-08-16 Solutech, Inc. Dialysis system 2nd method
US4726381A (en) * 1986-06-04 1988-02-23 Solutech, Inc. Dialysis system and method
US4781733A (en) 1986-07-23 1988-11-01 Bend Research, Inc. Semipermeable thin-film membranes comprising siloxane, alkoxysilyl and aryloxysilyl oligomers and copolymers
US4954381A (en) 1986-12-30 1990-09-04 The Research Foundation Of The State University Of New York Preparation of porous substrates having well defined morphology
DE3700119A1 (en) 1987-01-03 1988-07-14 Inst Diabetestechnologie Gemei IMPLANTABLE ELECTROCHEMICAL SENSOR
US4832034A (en) 1987-04-09 1989-05-23 Pizziconi Vincent B Method and apparatus for withdrawing, collecting and biosensing chemical constituents from complex fluids
US5352348A (en) 1987-04-09 1994-10-04 Nova Biomedical Corporation Method of using enzyme electrode
US6387379B1 (en) 1987-04-10 2002-05-14 University Of Florida Biofunctional surface modified ocular implants, surgical instruments, medical devices, prostheses, contact lenses and the like
US5094876A (en) 1987-04-10 1992-03-10 University Of Florida Surface modified surgical instruments, devices, implants, contact lenses and the like
US4961954A (en) 1987-04-10 1990-10-09 University Of Florida Surface modified surgical instruments, devices, implants, contact lenses and the like
US5100689A (en) 1987-04-10 1992-03-31 University Of Florida Surface modified surgical instruments, devices, implants, contact lenses and the like
IT1215491B (en) 1987-05-15 1990-02-14 Enricerche Spa BIOSENSOR WITH ENZYMATIC MEMBRANE CHEMICALLY CONNECTED TO A SEMICONDUCTIVE DEVICE.
US4880883A (en) 1987-06-03 1989-11-14 Wisconsin Alumni Research Foundation Biocompatible polyurethanes modified with lower alkyl sulfonate and lower alkyl carboxylate
US5286364A (en) * 1987-06-08 1994-02-15 Rutgers University Surface-modified electochemical biosensor
US4786657A (en) 1987-07-02 1988-11-22 Minnesota Mining And Manufacturing Company Polyurethanes and polyurethane/polyureas crosslinked using 2-glyceryl acrylate or 2-glyceryl methacrylate
JPH07122624B2 (en) 1987-07-06 1995-12-25 ダイキン工業株式会社 Biosensor
US4805625A (en) * 1987-07-08 1989-02-21 Ad-Tech Medical Instrument Corporation Sphenoidal electrode and insertion method
DE3725728A1 (en) 1987-08-04 1989-02-16 Freudenberg Carl Fa MEDICAL DEVICE AND METHOD FOR THE PRODUCTION THEREOF
US5221724A (en) 1987-08-12 1993-06-22 Wisconsin Alumni Research Foundation Polysiloxane polyurea urethanes
GB2209836A (en) 1987-09-16 1989-05-24 Cambridge Life Sciences Multilayer enzyme electrode membrane and method of making same
DE3736652A1 (en) 1987-10-29 1989-05-11 Bayer Ag PROCESS FOR PREPARING COATINGS
US5242835A (en) 1987-11-03 1993-09-07 Radiometer A/S Method and apparatus for determining the concentration of oxygen
GB8725936D0 (en) 1987-11-05 1987-12-09 Genetics Int Inc Sensing system
US5128408A (en) 1987-11-16 1992-07-07 Toyo Boseki Kabushiki Kaisha Gas-permeable material with excellent compatibility with blood
US4852573A (en) 1987-12-04 1989-08-01 Kennedy Philip R Implantable neural electrode
US4813424A (en) 1987-12-23 1989-03-21 University Of New Mexico Long-life membrane electrode for non-ionic species
US5070169A (en) 1988-02-26 1991-12-03 Ciba-Geigy Corporation Wettable, flexible, oxygen permeable contact lens containing block copolymer polysiloxane-polyoxyalkylene backbone units and use thereof
US4822336A (en) 1988-03-04 1989-04-18 Ditraglia John Blood glucose level sensing
US4951657A (en) 1988-04-22 1990-08-28 Dow Corning Corporation Heat sealable membrane for transdermal drug release
US4793555A (en) 1988-04-22 1988-12-27 Dow Corning Corporation Container, method and composition for controlling the release of a volatile liquid from an aqueous mixture
US4908208A (en) 1988-04-22 1990-03-13 Dow Corning Corporation Matrix for release of active ingredients
US4952618A (en) 1988-05-03 1990-08-28 Minnesota Mining And Manufacturing Company Hydrocolloid/adhesive composition
US5342693A (en) 1988-06-08 1994-08-30 Cardiopulmonics, Inc. Multifunctional thrombo-resistant coating and methods of manufacture
US4849458A (en) 1988-06-17 1989-07-18 Matrix Medica, Inc. Segmented polyether polyurethane
GB8817997D0 (en) 1988-07-28 1988-09-01 Cambridge Life Sciences Enzyme electrodes & improvements in manufacture thereof
EP0353328A1 (en) 1988-08-03 1990-02-07 Dräger Nederland B.V. A polarographic-amperometric three-electrode sensor
US5438984A (en) 1988-09-08 1995-08-08 Sudor Partners Apparatus and method for the collection of analytes on a dermal patch
US4960594A (en) 1988-09-22 1990-10-02 Derma-Lock Medical Corporation Polyurethane foam dressing
US4983702A (en) 1988-09-28 1991-01-08 Ciba-Geigy Corporation Crosslinked siloxane-urethane polymer contact lens
US6306594B1 (en) 1988-11-14 2001-10-23 I-Stat Corporation Methods for microdispensing patterened layers
US5063081A (en) 1988-11-14 1991-11-05 I-Stat Corporation Method of manufacturing a plurality of uniform microfabricated sensing devices having an immobilized ligand receptor
US5212050A (en) 1988-11-14 1993-05-18 Mier Randall M Method of forming a permselective layer
US5200051A (en) 1988-11-14 1993-04-06 I-Stat Corporation Wholly microfabricated biosensors and process for the manufacture and use thereof
US5458631A (en) 1989-01-06 1995-10-17 Xavier; Ravi Implantable catheter with electrical pulse nerve stimulators and drug delivery system
US5269891A (en) 1989-03-09 1993-12-14 Novo Nordisk A/S Method and apparatus for determination of a constituent in a fluid
JPH02298855A (en) 1989-03-20 1990-12-11 Assoc Univ Inc Electrochemical biosensor using immobilized enzyme and redox polymer
US4953552A (en) 1989-04-21 1990-09-04 Demarzo Arthur P Blood glucose monitoring system
EP0396788A1 (en) 1989-05-08 1990-11-14 Dräger Nederland B.V. Process and sensor for measuring the glucose content of glucosecontaining fluids
US4988341A (en) * 1989-06-05 1991-01-29 Eastman Kodak Company Sterilizing dressing device and method for skin puncture
US5034461A (en) 1989-06-07 1991-07-23 Bausch & Lomb Incorporated Novel prepolymers useful in biomedical devices
US5045601A (en) 1989-06-13 1991-09-03 Biointerface Technologies, Inc. Pressure-sensitive adhesive compositions suitable for medical uses
US5115056A (en) 1989-06-20 1992-05-19 Ciba-Geigy Corporation Fluorine and/or silicone containing poly(alkylene-oxide)-block copolymers and contact lenses thereof
US5334681A (en) 1989-06-20 1994-08-02 Ciba-Geigy Corporation Fluorine and/or silicone containing poly(alkylene-oxide)-block copolymer hydrogels and contact lenses thereof
CH677149A5 (en) 1989-07-07 1991-04-15 Disetronic Ag
US5264104A (en) 1989-08-02 1993-11-23 Gregg Brian A Enzyme electrodes
FR2650756B1 (en) 1989-08-11 1991-10-31 Inst Francais Du Petrole GAS SEPARATION MEMBRANE
US5050612A (en) 1989-09-12 1991-09-24 Matsumura Kenneth N Device for computer-assisted monitoring of the body
US5002590A (en) 1989-09-19 1991-03-26 Bend Research, Inc. Countercurrent dehydration by hollow fibers
JPH03133440A (en) 1989-10-18 1991-06-06 Nishitomo:Kk Clinical thermometer for ladies
US5010141A (en) 1989-10-25 1991-04-23 Ciba-Geigy Corporation Reactive silicone and/or fluorine containing hydrophilic prepolymers and polymers thereof
US5140985A (en) 1989-12-11 1992-08-25 Schroeder Jon M Noninvasive blood glucose measuring device
US5985129A (en) 1989-12-14 1999-11-16 The Regents Of The University Of California Method for increasing the service life of an implantable sensor
US5183549A (en) * 1990-01-26 1993-02-02 Commtech International Management Corporation Multi-analyte sensing electrolytic cell
US5108819A (en) 1990-02-14 1992-04-28 Eli Lilly And Company Thin film electrical component
US5316008A (en) 1990-04-06 1994-05-31 Casio Computer Co., Ltd. Measurement of electrocardiographic wave and sphygmus
US5165407A (en) 1990-04-19 1992-11-24 The University Of Kansas Implantable glucose sensor
GB9009409D0 (en) 1990-04-26 1990-06-20 Dow Corning Film-forming copolymers and their use in water vapour permeable coatings
US5331555A (en) 1990-05-11 1994-07-19 Sharp Kabushiki Kaisha Electronic apparatus
US5147725A (en) 1990-07-03 1992-09-15 Corvita Corporation Method for bonding silicone rubber and polyurethane materials and articles manufactured thereby
US5250439A (en) 1990-07-19 1993-10-05 Miles Inc. Use of conductive sensors in diagnostic assays
US5202261A (en) 1990-07-19 1993-04-13 Miles Inc. Conductive sensors and their use in diagnostic assays
US5746898A (en) 1990-08-10 1998-05-05 Siemens Aktiengesellschaft Electrochemical-enzymatic sensor
WO1992007464A1 (en) 1990-10-24 1992-05-14 University Of Florida Combined plasma and gamma radiation polymerization method for modifying surfaces
BR9106205A (en) 1990-10-31 1993-03-30 Baxter Int DEVICE FOR IMPLANTATION IN HOST, IMPLANTATION PROCESS, IMPLANTED DEVICE, AND IMMUNO INSULATION CONTAINER
US5135297A (en) 1990-11-27 1992-08-04 Bausch & Lomb Incorporated Surface coating of polymer objects
US5219965A (en) 1990-11-27 1993-06-15 Bausch & Lomb Incorporated Surface modification of polymer objects
EP0495478B1 (en) 1991-01-16 1999-04-21 Toyo Boseki Kabushiki Kaisha A material compatible with blood
US5593852A (en) 1993-12-02 1997-01-14 Heller; Adam Subcutaneous glucose electrode
US5773270A (en) 1991-03-12 1998-06-30 Chiron Diagnostics Corporation Three-layered membrane for use in an electrochemical sensor system
DK0585368T3 (en) 1991-04-25 1998-03-16 Univ Brown Res Found Implantable biocompatible immuno-insulating vehicle for delivery of selected therapeutic products
US5397848A (en) 1991-04-25 1995-03-14 Allergan, Inc. Enhancing the hydrophilicity of silicone polymers
US5271736A (en) 1991-05-13 1993-12-21 Applied Medical Research Collagen disruptive morphology for implants
ES2225819T3 (en) * 1991-09-20 2005-03-16 Amgen Inc. GLIAL ORIGIN NEUROTROPHIC FACTOR.
US5322063A (en) 1991-10-04 1994-06-21 Eli Lilly And Company Hydrophilic polyurethane membranes for electrochemical glucose sensors
US5155149A (en) 1991-10-10 1992-10-13 Boc Health Care, Inc. Silicone polyurethane copolymers containing oxygen sensitive phosphorescent dye compounds
US5249576A (en) 1991-10-24 1993-10-05 Boc Health Care, Inc. Universal pulse oximeter probe
US5296144A (en) 1992-01-02 1994-03-22 World Trade Corporation Composite membrane of a hydrophilic asymmetric membrane coated with an organosiloxane block copolymer
NL9200207A (en) 1992-02-05 1993-09-01 Nedap Nv IMPLANTABLE BIOMEDICAL SENSOR DEVICE, IN PARTICULAR FOR MEASUREMENT OF THE GLUCOSE CONCENTRATION.
US5284140A (en) 1992-02-11 1994-02-08 Eli Lilly And Company Acrylic copolymer membranes for biosensors
DE69319771T2 (en) 1992-03-31 1999-04-22 Dainippon Printing Co Ltd Immobilized enzyme electrode, composition for its production and electrically conductive enzymes
US5324322A (en) 1992-04-20 1994-06-28 Case Western Reserve University Thin film implantable electrode and method of manufacture
US5589563A (en) 1992-04-24 1996-12-31 The Polymer Technology Group Surface-modifying endgroups for biomedical polymers
DE69320470T2 (en) 1992-04-24 1999-04-29 Polymer Technology Group Inc COPOLYMERS AND NON-POROUS SEMI-PLEASANT MEMBRANES MADE THEREOF AND THEIR USE FOR FILTERING MOLECULES IN A PRESET MOLECULAR WEIGHT RANGE
GB9211402D0 (en) 1992-05-29 1992-07-15 Univ Manchester Sensor devices
US5208313A (en) 1992-07-16 1993-05-04 Surface Coatings, Inc. Waterproof breathable polyurethane membranes and porous substrates protected therewith
JP2541081B2 (en) * 1992-08-28 1996-10-09 日本電気株式会社 Biosensor and method of manufacturing and using biosensor
WO1994007593A1 (en) 1992-10-01 1994-04-14 Australian Membrane And Biotechnology Research Institute Improved sensor membranes
GB9221099D0 (en) 1992-10-07 1992-11-18 Ecossensors Ltd Improvements in and relating to gas permeable membranes for amperometric gas electrodes
US5387327A (en) 1992-10-19 1995-02-07 Duquesne University Of The Holy Ghost Implantable non-enzymatic electrochemical glucose sensor
US6256522B1 (en) 1992-11-23 2001-07-03 University Of Pittsburgh Of The Commonwealth System Of Higher Education Sensors for continuous monitoring of biochemicals and related method
US5299571A (en) 1993-01-22 1994-04-05 Eli Lilly And Company Apparatus and method for implantation of sensors
JPH06229973A (en) 1993-01-29 1994-08-19 Kyoto Daiichi Kagaku:Kk Current detection type dry ion selective electrode
US5389430A (en) 1993-02-05 1995-02-14 Th. Goldschmidt Ag Textiles coated with waterproof, moisture vapor permeable polymers
US5411866A (en) 1993-03-30 1995-05-02 National Research Council Of Canada Method and system for determining bioactive substances
US5387329A (en) 1993-04-09 1995-02-07 Ciba Corning Diagnostics Corp. Extended use planar sensors
US5964745A (en) 1993-07-02 1999-10-12 Med Usa Implantable system for cell growth control
CA2127817C (en) * 1993-07-13 2007-07-03 Hitoshi Tsugaya Tobacco filters and method of producing the same
DE4329898A1 (en) 1993-09-04 1995-04-06 Marcus Dr Besson Wireless medical diagnostic and monitoring device
US5582184A (en) 1993-10-13 1996-12-10 Integ Incorporated Interstitial fluid collection and constituent measurement
US5791344A (en) 1993-11-19 1998-08-11 Alfred E. Mann Foundation For Scientific Research Patient monitoring system
US5497772A (en) 1993-11-19 1996-03-12 Alfred E. Mann Foundation For Scientific Research Glucose monitoring system
DE4401400A1 (en) 1994-01-19 1995-07-20 Ernst Prof Dr Pfeiffer Method and arrangement for continuously monitoring the concentration of a metabolite
US5390671A (en) * 1994-03-15 1995-02-21 Minimed Inc. Transcutaneous sensor insertion set
US5391250A (en) * 1994-03-15 1995-02-21 Minimed Inc. Method of fabricating thin film sensors
US5569186A (en) 1994-04-25 1996-10-29 Minimed Inc. Closed loop infusion pump system with removable glucose sensor
US5584876A (en) 1994-04-29 1996-12-17 W. L. Gore & Associates, Inc. Cell excluding sheath for vascular grafts
DE4415896A1 (en) 1994-05-05 1995-11-09 Boehringer Mannheim Gmbh Analysis system for monitoring the concentration of an analyte in the blood of a patient
US5766839A (en) 1994-06-17 1998-06-16 Ysi Incorporated Processes for preparing barrier layer films for use in enzyme electrodes and films made thereby
US5429735A (en) 1994-06-27 1995-07-04 Miles Inc. Method of making and amperometric electrodes
US5494562A (en) * 1994-06-27 1996-02-27 Ciba Corning Diagnostics Corp. Electrochemical sensors
US5605152A (en) * 1994-07-18 1997-02-25 Minimed Inc. Optical glucose sensor
US6007845A (en) 1994-07-22 1999-12-28 Massachusetts Institute Of Technology Nanoparticles and microparticles of non-linear hydrophilic-hydrophobic multiblock copolymers
US5513636A (en) 1994-08-12 1996-05-07 Cb-Carmel Biotechnology Ltd. Implantable sensor chip
US5462051A (en) 1994-08-31 1995-10-31 Colin Corporation Medical communication system
US5624537A (en) 1994-09-20 1997-04-29 The University Of British Columbia - University-Industry Liaison Office Biosensor and interface membrane
US5552112A (en) 1995-01-26 1996-09-03 Quiclave, Llc Method and system for sterilizing medical instruments
CA2159052C (en) 1994-10-28 2007-03-06 Rainer Alex Injection device
IE72524B1 (en) 1994-11-04 1997-04-23 Elan Med Tech Analyte-controlled liquid delivery device and analyte monitor
WO1996015443A1 (en) * 1994-11-14 1996-05-23 Chiron Diagnostics Corporation_ RANDOMLY SEGMENTED THERMOPLASTIC POLYURETHANES AS MATRIX FOR ELECTROCHEMICAL ANALYSIS OF Ca++ IONS
US5670097A (en) 1994-12-08 1997-09-23 Minnesota Mining And Manufacturing Company Method of making blood gas sensors overcoats using permeable polymeric compositions
US5700559A (en) 1994-12-16 1997-12-23 Advanced Surface Technology Durable hydrophilic surface coatings
US5590651A (en) * 1995-01-17 1997-01-07 Temple University - Of The Commonwealth System Of Higher Education Breathable liquid elimination analysis
US5568806A (en) 1995-02-16 1996-10-29 Minimed Inc. Transcutaneous sensor insertion set
US5586553A (en) 1995-02-16 1996-12-24 Minimed Inc. Transcutaneous sensor insertion set
US5786439A (en) 1996-10-24 1998-07-28 Minimed Inc. Hydrophilic, swellable coatings for biosensors
US5882494A (en) * 1995-03-27 1999-03-16 Minimed, Inc. Polyurethane/polyurea compositions containing silicone for biosensor membranes
US5571401A (en) 1995-03-27 1996-11-05 California Institute Of Technology Sensor arrays for detecting analytes in fluids
SI0819258T1 (en) 1995-04-04 2002-04-30 Novartis Ag Extended wear ophthalmic lens
TW393498B (en) 1995-04-04 2000-06-11 Novartis Ag The preparation and use of Polysiloxane-comprising perfluoroalkyl ethers
JPH10503964A (en) 1995-06-07 1998-04-14 ゴア ハイブリッド テクノロジーズ,インコーポレイティド Implantable containment device for a therapeutic device and method for loading and reloading the device therein
US5743262A (en) 1995-06-07 1998-04-28 Masimo Corporation Blood glucose monitoring system
US5584813A (en) 1995-06-07 1996-12-17 Minimed Inc. Subcutaneous injection set
US5995860A (en) 1995-07-06 1999-11-30 Thomas Jefferson University Implantable sensor and system for measurement and control of blood constituent levels
US5611900A (en) * 1995-07-20 1997-03-18 Michigan State University Microbiosensor used in-situ
US5700902A (en) 1995-07-27 1997-12-23 Circe Biomedical, Inc. Block copolymers
US5735273A (en) 1995-09-12 1998-04-07 Cygnus, Inc. Chemical signal-impermeable mask
CN1200742A (en) 1995-09-26 1998-12-02 阿迈隆国际公司 Polysiloxane polyurethane compositions
US5665222A (en) 1995-10-11 1997-09-09 E. Heller & Company Soybean peroxidase electrochemical sensor
US5972199A (en) 1995-10-11 1999-10-26 E. Heller & Company Electrochemical analyte sensors using thermostable peroxidase
US6689265B2 (en) * 1995-10-11 2004-02-10 Therasense, Inc. Electrochemical analyte sensors using thermostable soybean peroxidase
US5855613A (en) 1995-10-13 1999-01-05 Islet Sheet Medical, Inc. Retrievable bioartificial implants having dimensions allowing rapid diffusion of oxygen and rapid biological response to physiological change
WO1997014405A1 (en) * 1995-10-16 1997-04-24 The Procter & Gamble Company Conditioning shampoos containing polyalkylene glycol
JPH11513688A (en) * 1995-10-16 1999-11-24 ザ、プロクター、エンド、ギャンブル、カンパニー Conditioning shampoo compositions with improved stability
US6002954A (en) 1995-11-22 1999-12-14 The Regents Of The University Of California Detection of biological molecules using boronate-based chemical amplification and optical sensors
WO1997019188A1 (en) 1995-11-22 1997-05-29 Minimed, Inc. Detection of biological molecules using chemical amplification and optical sensors
US5711861A (en) 1995-11-22 1998-01-27 Ward; W. Kenneth Device for monitoring changes in analyte concentration
DE69623647T2 (en) 1995-12-22 2003-05-28 Novartis Ag POLYURETHANE MADE OF POLYSILOXANE-POLYOL MACROMER
US5795453A (en) 1996-01-23 1998-08-18 Gilmartin; Markas A. T. Electrodes and metallo isoindole ringed compounds
US5932299A (en) 1996-04-23 1999-08-03 Katoot; Mohammad W. Method for modifying the surface of an object
US6407195B2 (en) 1996-04-25 2002-06-18 3M Innovative Properties Company Tackified polydiorganosiloxane oligourea segmented copolymers and a process for making same
US5820589A (en) 1996-04-30 1998-10-13 Medtronic, Inc. Implantable non-invasive rate-adjustable pump
US6022463A (en) * 1996-05-16 2000-02-08 Sendx Medical, Inc. Sensors with subminiature through holes
US5776324A (en) 1996-05-17 1998-07-07 Encelle, Inc. Electrochemical biosensors
US5914182A (en) 1996-06-03 1999-06-22 Gore Hybrid Technologies, Inc. Materials and methods for the immobilization of bioactive species onto polymeric substrates
JP2943700B2 (en) 1996-07-10 1999-08-30 日本電気株式会社 Biosensor
US5703359A (en) 1996-07-29 1997-12-30 Leybold Inficon, Inc. Composite membrane and support assembly
US5804048A (en) 1996-08-15 1998-09-08 Via Medical Corporation Electrode assembly for assaying glucose
US6018013A (en) * 1996-09-03 2000-01-25 Nkk Corporation Coating composition and method for producing precoated steel sheets
US5885566A (en) 1996-09-25 1999-03-23 University Of Florida Surface modified surgical instruments, medical devices, implants, contact lenses and the like
WO1998020960A1 (en) 1996-11-12 1998-05-22 Whatman, Inc. Hydrophilic polymeric phase inversion membrane
DK0944731T3 (en) 1996-11-14 2006-05-22 Radiometer Medical Aps enzyme Sensor
US5811487A (en) 1996-12-16 1998-09-22 Dow Corning Corporation Thickening silicones with elastomeric silicone polyethers
US5964993A (en) * 1996-12-19 1999-10-12 Implanted Biosystems Inc. Glucose sensor
US5914026A (en) 1997-01-06 1999-06-22 Implanted Biosystems Inc. Implantable sensor employing an auxiliary electrode
US6093172A (en) 1997-02-05 2000-07-25 Minimed Inc. Injector for a subcutaneous insertion set
US6891317B2 (en) * 2001-05-22 2005-05-10 Sri International Rolled electroactive polymers
US5977241A (en) 1997-02-26 1999-11-02 Integument Technologies, Inc. Polymer and inorganic-organic hybrid composites and methods for making same
US7192450B2 (en) 2003-05-21 2007-03-20 Dexcom, Inc. Porous membranes for use with implantable devices
US6001067A (en) 1997-03-04 1999-12-14 Shults; Mark C. Device and method for determining analyte levels
US7657297B2 (en) 2004-05-03 2010-02-02 Dexcom, Inc. Implantable analyte sensor
US7899511B2 (en) 2004-07-13 2011-03-01 Dexcom, Inc. Low oxygen in vivo analyte sensor
US6741877B1 (en) 1997-03-04 2004-05-25 Dexcom, Inc. Device and method for determining analyte levels
US6862465B2 (en) 1997-03-04 2005-03-01 Dexcom, Inc. Device and method for determining analyte levels
US20050033132A1 (en) * 1997-03-04 2005-02-10 Shults Mark C. Analyte measuring device
NZ500018A (en) 1997-03-31 2001-07-27 Alza Corp Diffusional implantable delivery system with capillary tube of cross-sectional area and length to deliver beneficial agent
US5961451A (en) 1997-04-07 1999-10-05 Motorola, Inc. Noninvasive apparatus having a retaining member to retain a removable biosensor
US6059946A (en) 1997-04-14 2000-05-09 Matsushita Electric Industrial Co., Ltd. Biosensor
US6018033A (en) * 1997-05-13 2000-01-25 Purdue Research Foundation Hydrophilic, hydrophobic, and thermoreversible saccharide gels and forms, and methods for producing same
US5954643A (en) 1997-06-09 1999-09-21 Minimid Inc. Insertion set for a transcutaneous sensor
EP0990151A2 (en) 1997-06-16 2000-04-05 ELAN CORPORATION, Plc Methods of calibrating and testing a sensor for (in vivo) measurement of an analyte and devices for use in such methods
US6013711A (en) 1997-06-18 2000-01-11 Ck Witco Corporation Hydrophilic polysiloxane compositions
GB9717906D0 (en) 1997-08-23 1997-10-29 Univ Manchester Sensor Devices And Analytical Methods
US6259937B1 (en) 1997-09-12 2001-07-10 Alfred E. Mann Foundation Implantable substrate sensor
US6119028A (en) 1997-10-20 2000-09-12 Alfred E. Mann Foundation Implantable enzyme-based monitoring systems having improved longevity due to improved exterior surfaces
US6081736A (en) * 1997-10-20 2000-06-27 Alfred E. Mann Foundation Implantable enzyme-based monitoring systems adapted for long term use
US6088608A (en) 1997-10-20 2000-07-11 Alfred E. Mann Foundation Electrochemical sensor and integrity tests therefor
US6030827A (en) * 1998-01-23 2000-02-29 I-Stat Corporation Microfabricated aperture-based sensor
US7052131B2 (en) 2001-09-10 2006-05-30 J&J Vision Care, Inc. Biomedical devices containing internal wetting agents
US6134461A (en) 1998-03-04 2000-10-17 E. Heller & Company Electrochemical analyte
GB9805896D0 (en) 1998-03-20 1998-05-13 Eglise David Remote analysis system
US6091975A (en) 1998-04-01 2000-07-18 Alza Corporation Minimally invasive detecting device
US6175752B1 (en) * 1998-04-30 2001-01-16 Therasense, Inc. Analyte monitoring device and methods of use
US6949816B2 (en) 2003-04-21 2005-09-27 Motorola, Inc. Semiconductor component having first surface area for electrically coupling to a semiconductor chip and second surface area for electrically coupling to a substrate, and method of manufacturing same
WO1999058050A1 (en) 1998-05-13 1999-11-18 Cygnus, Inc. Signal processing for measurement of physiological analytes
US5969076A (en) 1998-05-15 1999-10-19 Bausch & Lomb Incorporated Thermoplastic silicone-containing hydrogels
US6702972B1 (en) 1998-06-09 2004-03-09 Diametrics Medical Limited Method of making a kink-resistant catheter
US6294281B1 (en) 1998-06-17 2001-09-25 Therasense, Inc. Biological fuel cell and method
US6248067B1 (en) 1999-02-05 2001-06-19 Minimed Inc. Analyte sensor and holter-type monitor system and method of using the same
US6107083A (en) 1998-08-21 2000-08-22 Bayer Corporation Optical oxidative enzyme-based sensors
US6039913A (en) 1998-08-27 2000-03-21 Novartis Ag Process for the manufacture of an ophthalmic molding
US6180416B1 (en) * 1998-09-30 2001-01-30 Cygnus, Inc. Method and device for predicting physiological values
US6338790B1 (en) 1998-10-08 2002-01-15 Therasense, Inc. Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator
US6329488B1 (en) 1998-11-10 2001-12-11 C. R. Bard, Inc. Silane copolymer coatings
US6424847B1 (en) 1999-02-25 2002-07-23 Medtronic Minimed, Inc. Glucose monitor calibration methods
KR100342165B1 (en) 1999-03-25 2002-06-27 배병우 Solid-State Type Micro Reference Electrode with Self-Diagnostic Function
US6368658B1 (en) 1999-04-19 2002-04-09 Scimed Life Systems, Inc. Coating medical devices using air suspension
CA2369336A1 (en) 1999-04-22 2000-11-02 Cygnus, Inc. Hydrogel in an iontophoretic device to measure glucose
JP4801301B2 (en) 1999-06-18 2011-10-26 アボット ダイアベティス ケア インコーポレイテッド In vivo analyte sensor with limited mass transfer
US6368274B1 (en) 1999-07-01 2002-04-09 Medtronic Minimed, Inc. Reusable analyte sensor site and method of using the same
US7247138B2 (en) 1999-07-01 2007-07-24 Medtronic Minimed, Inc. Reusable analyte sensor site and method of using the same
US6413393B1 (en) 1999-07-07 2002-07-02 Minimed, Inc. Sensor including UV-absorbing polymer and method of manufacture
DE19935063A1 (en) 1999-07-28 2001-02-01 Basf Ag Graft polymers as gas hydrate inhibitors
US6346583B1 (en) 1999-08-25 2002-02-12 General Electric Company Polar solvent compatible polyethersiloxane elastomers
US6358557B1 (en) 1999-09-10 2002-03-19 Sts Biopolymers, Inc. Graft polymerization of substrate surfaces
US6343225B1 (en) 1999-09-14 2002-01-29 Implanted Biosystems, Inc. Implantable glucose sensor
US6541107B1 (en) 1999-10-25 2003-04-01 Dow Corning Corporation Nanoporous silicone resins having low dielectric constants
WO2001038873A2 (en) * 1999-11-24 2001-05-31 Biotronic Technologies, Inc. Devices and methods for detecting analytes using electrosensor having capture reagent
GB9928071D0 (en) 1999-11-29 2000-01-26 Polybiomed Ltd Blood compatible medical articles
KR100360774B1 (en) 1999-12-27 2002-11-13 한국전자통신연구원 Enzyme electrode sensor and manufacturing method thereof
US6895263B2 (en) 2000-02-23 2005-05-17 Medtronic Minimed, Inc. Real time self-adjusting calibration algorithm
US6303670B1 (en) 2000-02-25 2001-10-16 Nippon Paper Industries Co., Ltd. Cellulose based coating composition curable with ultraviolet ray
WO2001064344A2 (en) 2000-03-02 2001-09-07 Microchips, Inc. Microfabricated devices for the storage and selective exposure of chemicals and devices
US6551496B1 (en) 2000-03-03 2003-04-22 Ysi Incorporated Microstructured bilateral sensor
IT1314759B1 (en) 2000-05-08 2003-01-03 Menarini Farma Ind INSTRUMENTATION FOR MEASUREMENT AND CONTROL OF THE CONTENT OF GLUCOSIOLACTATE OR OTHER METABOLITES IN BIOLOGICAL FLUIDS
US6442413B1 (en) * 2000-05-15 2002-08-27 James H. Silver Implantable sensor
US7769420B2 (en) 2000-05-15 2010-08-03 Silver James H Sensors for detecting substances indicative of stroke, ischemia, or myocardial infarction
US7181261B2 (en) 2000-05-15 2007-02-20 Silver James H Implantable, retrievable, thrombus minimizing sensors
KR100409017B1 (en) 2000-06-23 2003-12-06 주식회사 엘지화학 Multi-component composite membrane and method for preparing the same
US6400974B1 (en) 2000-06-29 2002-06-04 Sensors For Medicine And Science, Inc. Implanted sensor processing system and method for processing implanted sensor output
JP2002055076A (en) 2000-09-08 2002-02-20 Nec Corp Electrochemical sensor
EP1310005B9 (en) 2000-08-12 2011-06-22 LG Chemical Co., Ltd. Multi-component composite film method for preparing the same
WO2002017210A2 (en) 2000-08-18 2002-02-28 Cygnus, Inc. Formulation and manipulation of databases of analyte and associated values
US6793789B2 (en) 2000-09-30 2004-09-21 Geun Sig Cha Reference electrode with a polymeric reference electrode membrane
US6692528B2 (en) * 2000-11-09 2004-02-17 The Polymer Technology Group Incorporated Devices that change size/shape via osmotic pressure
DE10060852A1 (en) 2000-12-06 2002-06-20 Hexal Ag Active ingredient-impermeable cover layer or removable protective layer of a transdermal therapeutic system containing absorbents and channel formers
US6642015B2 (en) * 2000-12-29 2003-11-04 Minimed Inc. Hydrophilic polymeric material for coating biosensors
US6721587B2 (en) 2001-02-15 2004-04-13 Regents Of The University Of California Membrane and electrode structure for implantable sensor
KR100406690B1 (en) 2001-03-05 2003-11-21 주식회사 엘지화학 Electrochemical device using multicomponent composite membrane film
US6952603B2 (en) 2001-03-16 2005-10-04 Roche Diagnostics Operations, Inc. Subcutaneous analyte sensor
FR2822383B1 (en) 2001-03-23 2004-12-17 Perouse Lab PROSTHESIS FOR PLASTIC RECONSTRUCTION WITH IMPROVED HYDROPHILICITY PROPERTIES, AND METHOD FOR OBTAINING SAME
US6528584B2 (en) 2001-04-12 2003-03-04 The University Of Akron Multi-component polymeric networks containing poly(ethylene glycol)
DE10119036C1 (en) * 2001-04-18 2002-12-12 Disetronic Licensing Ag Immersion sensor for measuring the concentration of an analyte using an oxidase
US6613379B2 (en) 2001-05-08 2003-09-02 Isense Corp. Implantable analyte sensor
US6932894B2 (en) 2001-05-15 2005-08-23 Therasense, Inc. Biosensor membranes composed of polymers containing heterocyclic nitrogens
US6960466B2 (en) 2001-05-31 2005-11-01 Instrumentation Laboratory Company Composite membrane containing a cross-linked enzyme matrix for a biosensor
US6837988B2 (en) 2001-06-12 2005-01-04 Lifescan, Inc. Biological fluid sampling and analyte measurement devices and methods
EP1399135B1 (en) 2001-06-28 2004-12-29 Microchips, Inc. Methods for hermetically sealing microchip reservoir devices
US6702857B2 (en) * 2001-07-27 2004-03-09 Dexcom, Inc. Membrane for use with implantable devices
US20030032874A1 (en) * 2001-07-27 2003-02-13 Dexcom, Inc. Sensor head for use with implantable devices
US7456025B2 (en) 2001-08-28 2008-11-25 Porex Corporation Sintered polymer membrane for analyte detection device
US6802957B2 (en) 2001-09-28 2004-10-12 Marine Biological Laboratory Self-referencing enzyme-based microsensor and method of use
WO2003046062A1 (en) 2001-11-21 2003-06-05 Porex Corporation Discrete hydrophilic-hydrophobic porous materials and methods for making the same
WO2003051191A1 (en) 2001-12-17 2003-06-26 Danfoss A/S Method and device for monitoring analyte concentration by optical detection
US6872927B2 (en) 2001-12-26 2005-03-29 Lambda Technologies, Inc. Systems and methods for processing pathogen-contaminated mail pieces
US7956525B2 (en) 2003-05-16 2011-06-07 Nanomix, Inc. Flexible nanostructure electronic devices
US20050154272A1 (en) 2002-01-23 2005-07-14 Danfoss A/S Method and device for monitoring analyte concentration by use of differential osmotic pressure measurement
WO2003063700A1 (en) 2002-01-29 2003-08-07 Sicel Technologies, Inc. Implantable sensor housing and fabrication methods
US8010174B2 (en) * 2003-08-22 2011-08-30 Dexcom, Inc. Systems and methods for replacing signal artifacts in a glucose sensor data stream
US7613491B2 (en) 2002-05-22 2009-11-03 Dexcom, Inc. Silicone based membranes for use in implantable glucose sensors
US7828728B2 (en) 2003-07-25 2010-11-09 Dexcom, Inc. Analyte sensor
US8364229B2 (en) 2003-07-25 2013-01-29 Dexcom, Inc. Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise
US20030157409A1 (en) 2002-02-21 2003-08-21 Sui-Yang Huang Polymer lithium battery with ionic electrolyte
DE10211051A1 (en) 2002-03-13 2003-10-02 Fresenius Medical Care De Gmbh Capillary membrane and device for producing the same
DE60334365D1 (en) 2002-03-22 2010-11-11 Animas Technologies Llc INCREASED PERFORMANCE OF AN ANALYSIS MONITORING DEVICE
EP1493015A4 (en) * 2002-04-05 2006-01-04 Powerzyme Inc Analyte sensor
US7813780B2 (en) 2005-12-13 2010-10-12 Medtronic Minimed, Inc. Biosensors and methods for making and using them
US20070227907A1 (en) 2006-04-04 2007-10-04 Rajiv Shah Methods and materials for controlling the electrochemistry of analyte sensors
FI118172B (en) 2002-04-22 2007-08-15 Inion Ltd Surgical implant
US7153265B2 (en) 2002-04-22 2006-12-26 Medtronic Minimed, Inc. Anti-inflammatory biosensor for reduced biofouling and enhanced sensor performance
US7008979B2 (en) 2002-04-30 2006-03-07 Hydromer, Inc. Coating composition for multiple hydrophilic applications
US7166235B2 (en) 2002-05-09 2007-01-23 The Procter & Gamble Company Compositions comprising anionic functionalized polyorganosiloxanes for hydrophobically modifying surfaces and enhancing delivery of active agents to surfaces treated therewith
CA2484374C (en) 2002-05-09 2011-05-17 Hemoteq Gmbh Medical products comprising a haemocompatible coating, production and use thereof
US6801041B2 (en) 2002-05-14 2004-10-05 Abbott Laboratories Sensor having electrode for determining the rate of flow of a fluid
US20060258761A1 (en) 2002-05-22 2006-11-16 Robert Boock Silicone based membranes for use in implantable glucose sensors
US7226978B2 (en) 2002-05-22 2007-06-05 Dexcom, Inc. Techniques to improve polyurethane membranes for implantable glucose sensors
US20030225324A1 (en) 2002-06-03 2003-12-04 Anderson Edward J. Noninvasive detection of a physiologic Parameter within a body tissue of a patient
US8996090B2 (en) * 2002-06-03 2015-03-31 Exostat Medical, Inc. Noninvasive detection of a physiologic parameter within a body tissue of a patient
WO2004007756A1 (en) 2002-07-12 2004-01-22 Novo Nordisk A/S Minimising calibration problems of in vivo glucose sensors
US20040106741A1 (en) 2002-09-17 2004-06-03 Kriesel Joshua W. Nanofilm compositions with polymeric components
WO2004034032A2 (en) 2002-10-11 2004-04-22 Case Western Reserve University Sliver type autonomous biosensors
US20040074785A1 (en) 2002-10-18 2004-04-22 Holker James D. Analyte sensors and methods for making them
KR100482285B1 (en) 2002-10-30 2005-04-14 한국전자통신연구원 Fluid-type multiple electrochemical system and the preparation thereof
AU2003298626A1 (en) 2002-11-12 2004-06-03 The Polymer Technology Group Incorporated Control of polymer surface molecular architecture via amphipathic endgroups
US20040111144A1 (en) 2002-12-06 2004-06-10 Lawin Laurie R. Barriers for polymeric coatings
US20040120848A1 (en) 2002-12-20 2004-06-24 Maria Teodorczyk Method for manufacturing a sterilized and calibrated biosensor-based medical device
US7120483B2 (en) 2003-01-13 2006-10-10 Isense Corporation Methods for analyte sensing and measurement
US7288609B1 (en) 2003-03-04 2007-10-30 Advanced Cardiovascular Systems, Inc. Coatings for drug delivery devices based on poly (orthoesters)
US6965791B1 (en) 2003-03-26 2005-11-15 Sorenson Medical, Inc. Implantable biosensor system, apparatus and method
US7279174B2 (en) * 2003-05-08 2007-10-09 Advanced Cardiovascular Systems, Inc. Stent coatings comprising hydrophilic additives
CA2525631C (en) 2003-05-13 2012-12-18 Medtronic, Inc. Moisture curable materials for delivery of agents, methods, and medical devices
WO2004101017A2 (en) 2003-05-16 2004-11-25 Blue Membranes Gmbh Medical implants comprising biocompatible coatings
CN1813020B (en) * 2003-05-21 2012-07-04 帝斯曼知识产权资产管理有限公司 Permselective structurally robust membrane material
US7875293B2 (en) 2003-05-21 2011-01-25 Dexcom, Inc. Biointerface membranes incorporating bioactive agents
US7687586B2 (en) 2003-05-21 2010-03-30 Isense Corporation Biosensor membrane material
US6789634B1 (en) 2003-05-28 2004-09-14 Smith International, Inc Self-lubricating elastomeric seal with polarized graphite
CA2527578A1 (en) 2003-06-06 2004-12-16 Humanautocell Gmbh Matrix, cell implantation and method for their production and use
US20050118344A1 (en) 2003-12-01 2005-06-02 Pacetti Stephen D. Temperature controlled crimping
DK200301027A (en) 2003-07-04 2005-01-05 Nkt Res & Innovation As A method of producing interpenetrating polymer networks (IPNs) and applications of IPNs
US8425926B2 (en) * 2003-07-16 2013-04-23 Yongxing Qiu Antimicrobial medical devices
WO2005010518A1 (en) 2003-07-23 2005-02-03 Dexcom, Inc. Rolled electrode array and its method for manufacture
US7651596B2 (en) 2005-04-08 2010-01-26 Dexcom, Inc. Cellulosic-based interference domain for an analyte sensor
US20050176136A1 (en) 2003-11-19 2005-08-11 Dexcom, Inc. Afinity domain for analyte sensor
US20070173709A1 (en) 2005-04-08 2007-07-26 Petisce James R Membranes for an analyte sensor
US7108778B2 (en) 2003-07-25 2006-09-19 Dexcom, Inc. Electrochemical sensors including electrode systems with increased oxygen generation
US7761130B2 (en) 2003-07-25 2010-07-20 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
WO2005012871A2 (en) 2003-07-25 2005-02-10 Dexcom, Inc. Increasing bias for oxygen production in an electrode system
US7366556B2 (en) * 2003-12-05 2008-04-29 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
JP2007500336A (en) 2003-07-25 2007-01-11 デックスコム・インコーポレーテッド Electrode system for electrochemical sensors
DE10335131A1 (en) 2003-07-31 2005-02-24 Blue Membranes Gmbh Porous carbon moldings, e.g. for catalyst support; insulant, tube membrane, ex or in vivo cell culture substrate or scaffold or implant, are made by molding carbonizable polymer and removing filler or partial oxidation to form pores
US7591801B2 (en) 2004-02-26 2009-09-22 Dexcom, Inc. Integrated delivery device for continuous glucose sensor
US8060173B2 (en) * 2003-08-01 2011-11-15 Dexcom, Inc. System and methods for processing analyte sensor data
US7172075B1 (en) * 2003-08-08 2007-02-06 Accord Partner Limited Defect free composite membranes, method for producing said membranes and use of the same
US7287043B2 (en) * 2003-08-21 2007-10-23 International Business Machines Corporation System and method for asynchronous data replication without persistence for distributed computing
US7920906B2 (en) 2005-03-10 2011-04-05 Dexcom, Inc. System and methods for processing analyte sensor data for sensor calibration
US7433727B2 (en) 2003-09-24 2008-10-07 Legacy Good Samaritan Hospital And Medical Center Implantable biosensor
DE602004026763D1 (en) * 2003-09-30 2010-06-02 Roche Diagnostics Gmbh SENSOR WITH IMPROVED BIOKOMPATIBILITY
AU2004288008B2 (en) 2003-10-31 2008-04-17 Lifescan Scotland Limited A method of reducing interferences in an electrochemical sensor using two different applied potentials
US7299082B2 (en) 2003-10-31 2007-11-20 Abbott Diabetes Care, Inc. Method of calibrating an analyte-measurement device, and associated methods, devices and systems
US7329413B1 (en) 2003-11-06 2008-02-12 Advanced Cardiovascular Systems, Inc. Coatings for drug delivery devices having gradient of hydration and methods for fabricating thereof
AU2004293463A1 (en) 2003-11-20 2005-06-09 Angiotech International Ag Implantable sensors and implantable pumps and anti-scarring agents
US7524455B2 (en) 2003-11-24 2009-04-28 General Electric Company Methods for deposition of sensor regions onto optical storage media substrates and resulting devices
US7807722B2 (en) 2003-11-26 2010-10-05 Advanced Cardiovascular Systems, Inc. Biobeneficial coating compositions and methods of making and using thereof
WO2005068528A1 (en) 2004-01-08 2005-07-28 Dutch Polymer Institute Polyurethanes, polyurethaneureas and polyureas and use thereof
US7699964B2 (en) 2004-02-09 2010-04-20 Abbott Diabetes Care Inc. Membrane suitable for use in an analyte sensor, analyte sensor, and associated method
US7364592B2 (en) 2004-02-12 2008-04-29 Dexcom, Inc. Biointerface membrane with macro-and micro-architecture
AU2005220150A1 (en) 2004-02-13 2005-09-15 The University Of North Carolina At Chapel Hill Functional materials and novel methods for the fabrication of microfluidic devices
WO2005084257A2 (en) 2004-02-26 2005-09-15 Vpn Solutions, Llc Composite thin-film glucose sensor
DE112005001005A5 (en) 2004-02-28 2007-05-24 Hemoteq Gmbh Biocompatible coating, process and use of medical surfaces
AU2004318179B2 (en) 2004-03-05 2009-07-23 Egomedical Swiss Ag Analyte test system for determining the concentration of an analyte in a physiological fluid
US8277713B2 (en) 2004-05-03 2012-10-02 Dexcom, Inc. Implantable analyte sensor
US20050245799A1 (en) 2004-05-03 2005-11-03 Dexcom, Inc. Implantable analyte sensor
US7118667B2 (en) 2004-06-02 2006-10-10 Jin Po Lee Biosensors having improved sample application and uses thereof
EP1754059B1 (en) 2004-06-09 2010-08-04 Becton, Dickinson and Company Multianalyte sensor
US20060015020A1 (en) * 2004-07-06 2006-01-19 Dexcom, Inc. Systems and methods for manufacture of an analyte-measuring device including a membrane system
US7246551B2 (en) * 2004-07-09 2007-07-24 Protedyne Corporation Liquid handling device with surface features at a seal
US8886272B2 (en) 2004-07-13 2014-11-11 Dexcom, Inc. Analyte sensor
WO2006127694A2 (en) 2004-07-13 2006-11-30 Dexcom, Inc. Analyte sensor
US20060016700A1 (en) * 2004-07-13 2006-01-26 Dexcom, Inc. Transcutaneous analyte sensor
JP4712365B2 (en) * 2004-08-13 2011-06-29 ルネサスエレクトロニクス株式会社 Nonvolatile semiconductor memory device and semiconductor memory device
WO2006127023A2 (en) 2004-08-24 2006-11-30 University Of South Florida Epoxy enhanced polymer membrane to increase durability of biosensors
US7244443B2 (en) 2004-08-31 2007-07-17 Advanced Cardiovascular Systems, Inc. Polymers of fluorinated monomers and hydrophilic monomers
US7229471B2 (en) 2004-09-10 2007-06-12 Advanced Cardiovascular Systems, Inc. Compositions containing fast-leaching plasticizers for improved performance of medical devices
US20060065527A1 (en) 2004-09-24 2006-03-30 Sendx Medical, Inc. Polymeric reference electrode
US9011831B2 (en) 2004-09-30 2015-04-21 Advanced Cardiovascular Systems, Inc. Methacrylate copolymers for medical devices
US20070299409A1 (en) 2004-11-09 2007-12-27 Angiotech Biocoatings Corp. Antimicrobial Needle Coating For Extended Infusion
US8377461B2 (en) * 2004-12-06 2013-02-19 Surmodics, Inc. Multifunctional medical articles
CN100367906C (en) * 2004-12-08 2008-02-13 圣美迪诺医疗科技(湖州)有限公司 Endermic implantating biological sensors
US7604818B2 (en) 2004-12-22 2009-10-20 Advanced Cardiovascular Systems, Inc. Polymers of fluorinated monomers and hydrocarbon monomers
ES2329272T3 (en) 2004-12-29 2009-11-24 BAUSCH & LOMB INCORPORATED POLISYLOXAN PREPOLIMEROS FOR BIOMEDICAL DEVICES.
MX2007007804A (en) 2004-12-29 2007-09-14 Bausch & Lomb Polysiloxane prepolymers for biomedical devices.
US20060142525A1 (en) 2004-12-29 2006-06-29 Bausch & Lomb Incorporated Hydrogel copolymers for biomedical devices
CN101107021A (en) 2004-12-30 2008-01-16 金文申有限公司 Combination comprising an agent providing a signal, an implant material and a drug
US20080213460A1 (en) 2005-01-17 2008-09-04 Maike Benter Method of Coating a Polymer Surface with a Polymer Containing Coating and an Item Comprising a Polymer Coated Polymer
JP4810099B2 (en) * 2005-01-20 2011-11-09 株式会社メニコン Transparent gel and contact lens comprising the same
US20060171980A1 (en) 2005-02-01 2006-08-03 Helmus Michael N Implantable or insertable medical devices having optimal surface energy
US7241586B2 (en) 2005-02-17 2007-07-10 Medtronic Minimed, Inc. Polypeptide formulations and methods for making, using and characterizing them
US20060249381A1 (en) 2005-05-05 2006-11-09 Petisce James R Cellulosic-based resistance domain for an analyte sensor
US8744546B2 (en) 2005-05-05 2014-06-03 Dexcom, Inc. Cellulosic-based resistance domain for an analyte sensor
JP5022621B2 (en) 2005-04-27 2012-09-12 三星エスディアイ株式会社 Cylindrical lithium secondary battery
US20060249446A1 (en) 2005-05-04 2006-11-09 Gary Yeager Solvent-resistant composite membrane composition
DK1885871T3 (en) 2005-05-17 2012-07-02 Radiometer Medical Aps Enzyme sensor with a cover membrane layer of a porous polymer material covered by a hydrophilic polymer
US20060263839A1 (en) 2005-05-17 2006-11-23 Isense Corporation Combined drug delivery and analyte sensor apparatus
US20060275859A1 (en) 2005-05-17 2006-12-07 Kjaer Thomas Enzyme sensor including a water-containing spacer layer
US20070123963A1 (en) 2005-11-29 2007-05-31 Peter Krulevitch Method for producing flexible, stretchable, and implantable high-density microelectrode arrays
US20070129524A1 (en) 2005-12-06 2007-06-07 Sunkara Hari B Thermoplastic polyurethanes comprising polytrimethylene ether soft segments
US7759408B2 (en) 2005-12-21 2010-07-20 Bausch & Lomb Incorporated Silicon-containing monomers end-capped with polymerizable cationic hydrophilic groups
US20070155851A1 (en) 2005-12-30 2007-07-05 Azaam Alli Silicone containing polymers formed from non-reactive silicone containing prepolymers
US20070161769A1 (en) 2006-01-06 2007-07-12 Schorzman Derek A Polymerizable silicon-containing monomer bearing pendant cationic hydrophilic groups
CA2577760A1 (en) 2006-02-27 2007-08-27 Tyco Healthcare Group Lp Pressurized dip coating system
AU2007221172A1 (en) 2006-02-27 2007-09-07 Edwards Lifesciences Corporation Flux limiting membrane for intravenous amperometric biosensor
US20070233013A1 (en) 2006-03-31 2007-10-04 Schoenberg Stephen J Covers for tissue engaging members
US7960447B2 (en) 2006-04-13 2011-06-14 Bausch & Lomb Incorporated Cationic end-capped siloxane prepolymer for reduced cross-link density
US7468397B2 (en) * 2006-06-30 2008-12-23 Bausch & Lomb Incorporated Polymerizable siloxane-quaternary amine copolymers
EP2054476B9 (en) 2006-07-25 2012-03-14 Glumetrics, Inc. Flourescent dyes for use in glucose sensing
US8114023B2 (en) * 2006-07-28 2012-02-14 Legacy Emanuel Hospital & Health Center Analyte sensing and response system
TWI315493B (en) * 2006-08-03 2009-10-01 Holtek Semiconductor Inc Transponder for rfid
US7871456B2 (en) * 2006-08-10 2011-01-18 The Regents Of The University Of California Membranes with controlled permeability to polar and apolar molecules in solution and methods of making same
US20080076897A1 (en) 2006-09-27 2008-03-27 Kunzler Jay F Pendant end-capped low modulus cationic siloxanyls
JP2008086855A (en) 2006-09-29 2008-04-17 Fujifilm Corp Biochemical instrument
US20080143014A1 (en) 2006-12-18 2008-06-19 Man-Wing Tang Asymmetric Gas Separation Membranes with Superior Capabilities for Gas Separation
US7751863B2 (en) 2007-02-06 2010-07-06 Glumetrics, Inc. Optical determination of ph and glucose
JP2010517693A (en) 2007-02-06 2010-05-27 グルメトリクス, インコーポレイテッド Optical system and method for ratiometric measurement of blood glucose concentration
EP2122334B1 (en) 2007-02-06 2018-01-24 Medtronic Minimed, Inc. Method for polymerizing a monomer solution within a cavity to generate a smooth polymer surface
US7824918B2 (en) 2007-08-06 2010-11-02 Glumetrics, Inc. HPTS-Mono and BIS Cys-Ma polymerizable fluorescent dyes for use in analyte sensors
US8088097B2 (en) 2007-11-21 2012-01-03 Glumetrics, Inc. Use of an equilibrium intravascular sensor to achieve tight glycemic control
CA2684511A1 (en) 2007-05-01 2008-11-13 Glumetrics, Inc. Pyridinium boronic acid quenchers for use in analyte sensors
WO2008141243A2 (en) * 2007-05-10 2008-11-20 Glumetrics, Inc. Device and methods for calibrating analyte sensors
WO2008141241A1 (en) * 2007-05-10 2008-11-20 Glumetrics, Inc. Equilibrium non-consuming fluorescence sensor for real time intravascular glucose measurement
US7691917B2 (en) 2007-06-14 2010-04-06 Bausch & Lomb Incorporated Silcone-containing prepolymers
US20090004243A1 (en) * 2007-06-29 2009-01-01 Pacetti Stephen D Biodegradable triblock copolymers for implantable devices
JP5675350B2 (en) 2007-07-11 2015-02-25 メドトロニック ミニメド インコーポレイテッド Polyviologen compound, method for synthesizing the compound, glucose sensor, and composition for measuring glucose
CN102047101A (en) 2008-03-28 2011-05-04 德克斯康公司 Polymer membranes for continuous analyte sensors
WO2009129186A2 (en) 2008-04-17 2009-10-22 Glumetrics, Inc. Sensor for percutaneous intravascular deployment without an indwelling cannula

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6973706B2 (en) * 1998-03-04 2005-12-13 Therasense, Inc. Method of making a transcutaneous electrochemical sensor
US20050054909A1 (en) * 2003-07-25 2005-03-10 James Petisce Oxygen enhancing membrane systems for implantable devices
US20050090607A1 (en) * 2003-10-28 2005-04-28 Dexcom, Inc. Silicone composition for biocompatible membrane
WO2005044088A2 (en) * 2003-11-03 2005-05-19 Children's Medical Center Corporation Continuous analyte monitor and method of using same
US20060036143A1 (en) * 2004-07-13 2006-02-16 Dexcom, Inc. Transcutaneous analyte sensor

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