WO2008005270A3 - Local and non-local sensing for cardiac pacing - Google Patents

Local and non-local sensing for cardiac pacing Download PDF

Info

Publication number
WO2008005270A3
WO2008005270A3 PCT/US2007/014968 US2007014968W WO2008005270A3 WO 2008005270 A3 WO2008005270 A3 WO 2008005270A3 US 2007014968 W US2007014968 W US 2007014968W WO 2008005270 A3 WO2008005270 A3 WO 2008005270A3
Authority
WO
WIPO (PCT)
Prior art keywords
local
feature
timing
signal
activation
Prior art date
Application number
PCT/US2007/014968
Other languages
French (fr)
Other versions
WO2008005270A8 (en
WO2008005270A2 (en
Inventor
Alok S Sathaye
Aaron R Mccabe
Yinghong Yu
Original Assignee
Cardiac Pacemakers Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cardiac Pacemakers Inc filed Critical Cardiac Pacemakers Inc
Priority to EP07809967.8A priority Critical patent/EP2038007B1/en
Priority to JP2009518259A priority patent/JP5184525B2/en
Publication of WO2008005270A2 publication Critical patent/WO2008005270A2/en
Publication of WO2008005270A3 publication Critical patent/WO2008005270A3/en
Publication of WO2008005270A8 publication Critical patent/WO2008005270A8/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/362—Heart stimulators
    • A61N1/365—Heart stimulators controlled by a physiological parameter, e.g. heart potential
    • A61N1/36585—Heart stimulators controlled by a physiological parameter, e.g. heart potential controlled by two or more physical parameters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316—Modalities, i.e. specific diagnostic methods
    • A61B5/318—Heart-related electrical modalities, e.g. electrocardiography [ECG]
    • A61B5/346—Analysis of electrocardiograms
    • A61B5/349—Detecting specific parameters of the electrocardiograph cycle
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/362—Heart stimulators
    • A61N1/365—Heart stimulators controlled by a physiological parameter, e.g. heart potential
    • A61N1/368—Heart stimulators controlled by a physiological parameter, e.g. heart potential comprising more than one electrode co-operating with different heart regions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/362—Heart stimulators
    • A61N1/365—Heart stimulators controlled by a physiological parameter, e.g. heart potential
    • A61N1/368—Heart stimulators controlled by a physiological parameter, e.g. heart potential comprising more than one electrode co-operating with different heart regions
    • A61N1/3684—Heart stimulators controlled by a physiological parameter, e.g. heart potential comprising more than one electrode co-operating with different heart regions for stimulating the heart at multiple sites of the ventricle or the atrium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/362—Heart stimulators
    • A61N1/365—Heart stimulators controlled by a physiological parameter, e.g. heart potential
    • A61N1/368—Heart stimulators controlled by a physiological parameter, e.g. heart potential comprising more than one electrode co-operating with different heart regions
    • A61N1/3682—Heart stimulators controlled by a physiological parameter, e.g. heart potential comprising more than one electrode co-operating with different heart regions with a variable atrioventricular delay
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/362—Heart stimulators
    • A61N1/365—Heart stimulators controlled by a physiological parameter, e.g. heart potential
    • A61N1/368—Heart stimulators controlled by a physiological parameter, e.g. heart potential comprising more than one electrode co-operating with different heart regions
    • A61N1/3684—Heart stimulators controlled by a physiological parameter, e.g. heart potential comprising more than one electrode co-operating with different heart regions for stimulating the heart at multiple sites of the ventricle or the atrium
    • A61N1/36843—Bi-ventricular stimulation

Abstract

Systems and methods for determining pacing timing intervals based on the temporal relationship between the timing of local and non-local cardiac signal features are described. A device includes a plurality of implantable electrodes electrically coupled to the heart and configured to sense local and non-local cardiac signals. Sense circuitry coupled to first and second electrode pairs senses a local cardiac signal via a first electrode pair and a non-local cardiac signal via a second electrode pair. Detection circuitry is used to detect a feature of the local signal associated with activation of a heart chamber and to detect a feature of the non-local signal associated with activation of the heart chamber. A control processor times delivery of one or more pacing pulses based on a temporal relationship between timing of the local signal feature and timing of the non-local signal feature.
PCT/US2007/014968 2006-06-29 2007-06-27 Local and non-local sensing for cardiac pacing WO2008005270A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP07809967.8A EP2038007B1 (en) 2006-06-29 2007-06-27 Local and non-local sensing for cardiac pacing
JP2009518259A JP5184525B2 (en) 2006-06-29 2007-06-27 Cardiac pacing therapy supply system

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/478,286 2006-06-29
US11/478,286 US8527048B2 (en) 2006-06-29 2006-06-29 Local and non-local sensing for cardiac pacing

Publications (3)

Publication Number Publication Date
WO2008005270A2 WO2008005270A2 (en) 2008-01-10
WO2008005270A3 true WO2008005270A3 (en) 2008-04-10
WO2008005270A8 WO2008005270A8 (en) 2008-06-05

Family

ID=38686660

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/014968 WO2008005270A2 (en) 2006-06-29 2007-06-27 Local and non-local sensing for cardiac pacing

Country Status (4)

Country Link
US (1) US8527048B2 (en)
EP (1) EP2038007B1 (en)
JP (1) JP5184525B2 (en)
WO (1) WO2008005270A2 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8983602B2 (en) 2007-08-07 2015-03-17 Cardiac Pacemakers, Inc. Method and apparatus to perform electrode combination selection
US9533160B2 (en) 2007-08-07 2017-01-03 Cardiac Pacemakers, Inc. Method and apparatus to perform electrode combination selection

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060178556A1 (en) 2001-06-29 2006-08-10 Intuitive Surgical, Inc. Articulate and swapable endoscope for a surgical robot
US6817974B2 (en) 2001-06-29 2004-11-16 Intuitive Surgical, Inc. Surgical tool having positively positionable tendon-actuated multi-disk wrist joint
CN100389730C (en) 2002-12-06 2008-05-28 直观外科手术公司 Flexible wrist for surgical tool
US20060247693A1 (en) 2005-04-28 2006-11-02 Yanting Dong Non-captured intrinsic discrimination in cardiac pacing response classification
US7774064B2 (en) * 2003-12-12 2010-08-10 Cardiac Pacemakers, Inc. Cardiac response classification using retriggerable classification windows
US8521284B2 (en) * 2003-12-12 2013-08-27 Cardiac Pacemakers, Inc. Cardiac response classification using multisite sensing and pacing
US7706866B2 (en) * 2004-06-24 2010-04-27 Cardiac Pacemakers, Inc. Automatic orientation determination for ECG measurements using multiple electrodes
US7805185B2 (en) 2005-05-09 2010-09-28 Cardiac Pacemakers, In. Posture monitoring using cardiac activation sequences
US7917196B2 (en) 2005-05-09 2011-03-29 Cardiac Pacemakers, Inc. Arrhythmia discrimination using electrocardiograms sensed from multiple implanted electrodes
US7509170B2 (en) * 2005-05-09 2009-03-24 Cardiac Pacemakers, Inc. Automatic capture verification using electrocardiograms sensed from multiple implanted electrodes
US7457664B2 (en) 2005-05-09 2008-11-25 Cardiac Pacemakers, Inc. Closed loop cardiac resynchronization therapy using cardiac activation sequence information
US7797036B2 (en) * 2004-11-30 2010-09-14 Cardiac Pacemakers, Inc. Cardiac activation sequence monitoring for ischemia detection
US7890159B2 (en) * 2004-09-30 2011-02-15 Cardiac Pacemakers, Inc. Cardiac activation sequence monitoring and tracking
US7392086B2 (en) * 2005-04-26 2008-06-24 Cardiac Pacemakers, Inc. Implantable cardiac device and method for reduced phrenic nerve stimulation
US8527048B2 (en) 2006-06-29 2013-09-03 Cardiac Pacemakers, Inc. Local and non-local sensing for cardiac pacing
US9345887B2 (en) 2006-06-29 2016-05-24 Cardiac Pacemakers Inc. Local and non-local sensing for cardiac pacing
US20080004665A1 (en) * 2006-06-29 2008-01-03 Mccabe Aaron R Determination of cardiac pacing parameters based on non-localized sensing
US8209013B2 (en) * 2006-09-14 2012-06-26 Cardiac Pacemakers, Inc. Therapeutic electrical stimulation that avoids undesirable activation
CN101939051B (en) 2008-02-14 2013-07-10 心脏起搏器公司 Method and apparatus for phrenic stimulation detection
US20090234413A1 (en) 2008-03-13 2009-09-17 Sambelashvili Aleksandre T Apparatus and methods of adjusting atrioventricular pacing delay intervals in a rate adaptive pacemaker
US7941218B2 (en) * 2008-03-13 2011-05-10 Medtronic, Inc. Apparatus and methods of optimizing atrioventricular pacing delay intervals
US8321014B2 (en) * 2008-10-06 2012-11-27 Cardiac Pacemakers, Inc. Dynamic cardiac resynchronization therapy by tracking intrinsic conduction
US9026209B2 (en) * 2009-07-28 2015-05-05 Biotronik Crm Patent Ag Ventricular cardiac stimulator
EP2734267B1 (en) * 2011-07-22 2018-11-21 Cardiac Pacemakers, Inc. Optimization of lv and rv lead placement based on electrical delays
US10004906B2 (en) 2015-07-16 2018-06-26 Medtronic, Inc. Confirming sensed atrial events for pacing during resynchronization therapy in a cardiac medical device and medical device system
WO2018081237A1 (en) 2016-10-27 2018-05-03 Cardiac Pacemakers, Inc. Use of a separate device in managing the pace pulse energy of a cardiac pacemaker
US10694967B2 (en) 2017-10-18 2020-06-30 Medtronic, Inc. State-based atrial event detection
US20220161032A1 (en) * 2020-11-24 2022-05-26 Medtronic, Inc. Guiding anti-tachyarrhythmia pacing train design and electrode selection with electrograms

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0560569A2 (en) * 1992-03-09 1993-09-15 Angemed, Inc. Fibrillation and tachycardia detection
WO2002040097A1 (en) * 2000-11-17 2002-05-23 St. Jude Medical Ab A cardiac stimulating device
WO2002047761A2 (en) * 2000-12-14 2002-06-20 Medtronic, Inc. Atrial aware vvi: a method for atrial synchronous ventricular (vdd/r) pacing using the subcutaneous electrode array and a standard pacing lead
WO2005089865A1 (en) * 2004-03-17 2005-09-29 Medtronic, Inc. Apparatus and methods of energy efficient, atrial-based bi-ventricular fusion-pacing
US6993379B1 (en) * 2002-12-30 2006-01-31 Pacesetter, Inc. System and method for emulating a surface EKG using an implantable cardiac stimulation device
EP1629863A1 (en) * 2004-08-27 2006-03-01 Pacesetter, Inc. System and method for determining optimal atrioventricular delay based on intrinsic conduction delays

Family Cites Families (293)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US725962A (en) * 1902-06-18 1903-04-21 Sylvester W Higgins Minnow-net.
US3920005A (en) 1972-03-16 1975-11-18 Medtronic Inc Evaluation system for cardiac stimulators
US4686332A (en) 1986-06-26 1987-08-11 International Business Machines Corporation Combined finger touch and stylus detection system for use on the viewing surface of a visual display device
US4388927A (en) 1979-12-13 1983-06-21 American Hospital Supply Corporation Programmable digital cardiac pacer
US4562841A (en) 1982-08-05 1986-01-07 Cardiac Pacemakers, Inc. Programmable multi-mode cardiac pacemaker
US4550221A (en) 1983-10-07 1985-10-29 Scott Mabusth Touch sensitive control device
US4953551A (en) 1987-01-14 1990-09-04 Medtronic, Inc. Method of defibrillating a heart
US5047930A (en) 1987-06-26 1991-09-10 Nicolet Instrument Corporation Method and system for analysis of long term physiological polygraphic recordings
US4878497A (en) 1988-03-25 1989-11-07 Telectronics N.V. Pacemaker with improved automatic output regulation
US4928688A (en) 1989-01-23 1990-05-29 Mieczyslaw Mirowski Method and apparatus for treating hemodynamic disfunction
US5111812A (en) 1990-01-23 1992-05-12 Cardiac Pacemakers, Inc. Defilbrillation electrode having smooth current distribution
US5036849A (en) 1990-04-04 1991-08-06 Cardiac Pacemakers, Inc. Variable rate cardiac pacer
US5284136A (en) 1990-04-04 1994-02-08 Cardiac Pacemakers, Inc. Dual indifferent electrode pacemaker
US5713926A (en) 1990-04-25 1998-02-03 Cardiac Pacemakers, Inc. Implantable intravenous cardiac stimulation system with pulse generator housing serving as optional additional electrode
US5133353A (en) 1990-04-25 1992-07-28 Cardiac Pacemakers, Inc. Implantable intravenous cardiac stimulation system with pulse generator housing serving as optional additional electrode
US5230337A (en) 1990-06-06 1993-07-27 Cardiac Pacemakers, Inc. Process for implanting subcutaneous defibrillation electrodes
US5203348A (en) 1990-06-06 1993-04-20 Cardiac Pacemakers, Inc. Subcutaneous defibrillation electrodes
US5105810A (en) 1990-07-24 1992-04-21 Telectronics Pacing Systems, Inc. Implantable automatic and haemodynamically responsive cardioverting/defibrillating pacemaker with means for minimizing bradycardia support pacing voltages
US5271411A (en) 1990-09-21 1993-12-21 Colin Electronics Co., Ltd. Method and apparatus for ECG signal analysis and cardiac arrhythmia detection
US5222493A (en) 1990-10-01 1993-06-29 Siemens Pacesetter, Inc. Verification of capture using an indifferent electrode mounted on the pacemaker connector top
US5170784A (en) 1990-11-27 1992-12-15 Ceon Ramon Leadless magnetic cardiac pacemaker
US5179945A (en) 1991-01-17 1993-01-19 Cardiac Pacemakers, Inc. Defibrillation/cardioversion system with multiple evaluation of heart condition prior to shock delivery
US5405363A (en) 1991-03-15 1995-04-11 Angelon Corporation Implantable cardioverter defibrillator having a smaller displacement volume
JP2655204B2 (en) * 1991-04-05 1997-09-17 メドトロニック インコーポレーテッド Implantable medical device
US5209229A (en) 1991-05-20 1993-05-11 Telectronics Pacing Systems, Inc. Apparatus and method employing plural electrode configurations for cardioversion of atrial fibrillation in an arrhythmia control system
US5300106A (en) 1991-06-07 1994-04-05 Cardiac Pacemakers, Inc. Insertion and tunneling tool for a subcutaneous wire patch electrode
FR2680093B1 (en) 1991-08-09 1993-10-29 Ela Medical METHOD FOR CONTROLLING THE STIMULATION ENERGY IN A HEART STIMULATOR.
US5313953A (en) 1992-01-14 1994-05-24 Incontrol, Inc. Implantable cardiac patient monitor
US5411525A (en) 1992-01-30 1995-05-02 Cardiac Pacemakers, Inc. Dual capacitor biphasic defibrillator waveform generator employing selective connection of capacitors for each phase
EP0553864B1 (en) 1992-01-30 1999-10-27 Cardiac Pacemakers, Inc. Defibrillator waveform generator for generating waveform of long duration
US5312445A (en) * 1992-02-03 1994-05-17 Telectronics Pacing Systems, Inc. Implantable cardiac stimulating apparatus and method employing detection of P-waves from signals sensed in the ventricle
US5301677A (en) 1992-02-06 1994-04-12 Cardiac Pacemakers, Inc. Arrhythmia detector using delta modulated turning point morphology of the ECG wave
US5261400A (en) 1992-02-12 1993-11-16 Medtronic, Inc. Defibrillator employing transvenous and subcutaneous electrodes and method of use
US5224486A (en) 1992-02-28 1993-07-06 Hewlett-Packard Company Method and apparatus for classifying heartbeat waveforms
US5439482A (en) 1992-04-07 1995-08-08 Angeion Corporation Prophylactic implantable cardioverter-defibrillator
US5324310A (en) 1992-07-01 1994-06-28 Medtronic, Inc. Cardiac pacemaker with auto-capture function
US5231990A (en) * 1992-07-09 1993-08-03 Spacelabs, Medical, Inc. Application specific integrated circuit for physiological monitoring
US5292338A (en) 1992-07-30 1994-03-08 Medtronic, Inc. Atrial defibrillator employing transvenous and subcutaneous electrodes and method of use
ATE176404T1 (en) 1992-09-30 1999-02-15 Cardiac Pacemakers Inc HINGED CUSHION ELECTRODE FOR CARDIAC REACH WITH A LADDER-FREE AREA THAT SERVES AS A HINGE
DE69315704T3 (en) 1992-10-01 2002-08-01 Cardiac Pacemakers Inc STENT-LIKE STRUCTURE FOR DEFLICTION ELECTRODES
US5441518A (en) 1993-07-22 1995-08-15 Angeion Corporation Implantable cardioverter defibrillator system having independently controllable electrode discharge pathway
US5334222A (en) 1992-11-03 1994-08-02 Cardiac Pacemakers, Inc. Cardiac stimulating apparatus and method for heart failure therapy
US5350410A (en) 1992-11-23 1994-09-27 Siemens Pacesetter, Inc. Autocapture system for implantable pulse generator
US5496362A (en) 1992-11-24 1996-03-05 Cardiac Pacemakers, Inc. Implantable conformal coil patch electrode with multiple conductive elements for cardioversion and defibrillation
US5342402A (en) 1993-01-29 1994-08-30 Medtronic, Inc. Method and apparatus for detection and treatment of tachycardia and fibrillation
US5697953A (en) 1993-03-13 1997-12-16 Angeion Corporation Implantable cardioverter defibrillator having a smaller displacement volume
US5318597A (en) 1993-03-15 1994-06-07 Cardiac Pacemakers, Inc. Rate adaptive cardiac rhythm management device control algorithm using trans-thoracic ventilation
US5366496A (en) 1993-04-01 1994-11-22 Cardiac Pacemakers, Inc. Subcutaneous shunted coil electrode
US5333095A (en) 1993-05-03 1994-07-26 Maxwell Laboratories, Inc., Sierra Capacitor Filter Division Feedthrough filter capacitor assembly for human implant
US5397342A (en) 1993-06-07 1995-03-14 Cardiac Pacemakers, Inc. Resilient structurally coupled and electrically independent electrodes
US5314430A (en) 1993-06-24 1994-05-24 Medtronic, Inc. Atrial defibrillator employing transvenous and subcutaneous electrodes and method of use
US5468254A (en) 1993-07-26 1995-11-21 Cardiac Pacemakers, Inc. Method and apparatus for defibrillation using a multiphasic truncated exponential waveform
US5411539A (en) 1993-08-31 1995-05-02 Medtronic, Inc. Active can emulator and method of use
US5443485A (en) 1993-09-08 1995-08-22 Intermedics, Inc. Apparatus and method for capture detection in a cardiac stimulator
US5372606A (en) 1993-10-07 1994-12-13 Cardiac Pacemakers, Inc. Method and apparatus for generating adaptive n-phasic defibrillation waveforms
US5331996A (en) 1993-10-08 1994-07-26 Ziehm Raymond G Dual mode hot water circulation apparatus
US5376106A (en) 1993-10-18 1994-12-27 Cardiac Pacemakers, Inc. Multi-sensor blending in a rate responsive cardiac pacemaker
US5411031A (en) 1993-11-24 1995-05-02 Incontrol, Inc. Implantable cardiac patient monitor
US5431693A (en) 1993-12-10 1995-07-11 Intermedics, Inc. Method of verifying capture of the heart by a pacemaker
US5641326A (en) 1993-12-13 1997-06-24 Angeion Corporation Method and apparatus for independent atrial and ventricular defibrillation
US5713367A (en) 1994-01-26 1998-02-03 Cambridge Heart, Inc. Measuring and assessing cardiac electrical stability
GB9406702D0 (en) 1994-04-05 1994-05-25 Binstead Ronald P Multiple input proximity detector and touchpad system
WO2000033244A2 (en) 1998-11-27 2000-06-08 Synaptics (Uk) Limited Position sensor
US5957956A (en) 1994-06-21 1999-09-28 Angeion Corp Implantable cardioverter defibrillator having a smaller mass
US7027868B2 (en) 2001-10-30 2006-04-11 Medtronic, Inc. Capture management improvements
US5520191A (en) 1994-10-07 1996-05-28 Ortivus Medical Ab Myocardial ischemia and infarction analysis and monitoring method and apparatus
US5540727A (en) 1994-11-15 1996-07-30 Cardiac Pacemakers, Inc. Method and apparatus to automatically optimize the pacing mode and pacing cycle parameters of a dual chamber pacemaker
US5724984A (en) 1995-01-26 1998-03-10 Cambridge Heart, Inc. Multi-segment ECG electrode and system
US5626620A (en) 1995-02-21 1997-05-06 Medtronic, Inc. Dual chamber pacing system and method with continual adjustment of the AV escape interval so as to maintain optimized ventricular pacing for treating cardiomyopathy
US5545186A (en) 1995-03-30 1996-08-13 Medtronic, Inc. Prioritized rule based method and apparatus for diagnosis and treatment of arrhythmias
US5674254A (en) 1995-05-22 1997-10-07 Vitatron Medical, B.V. Cardiac pacemaker system and method for determining a measure of pacing threshold without incurring loss of capture
US5605158A (en) 1995-08-02 1997-02-25 Pacesetter, Inc. Apparatus for annotating physiological waveforms
US5662688A (en) 1995-08-14 1997-09-02 Cardiac Pacemakers, Inc. Slow gain control
US5620466A (en) 1995-08-14 1997-04-15 Cardiac Pacemakers, Inc. Digital AGC using separate gain control and threshold templating
US5650759A (en) 1995-11-09 1997-07-22 Hittman Materials & Medical Components, Inc. Filtered feedthrough assembly having a mounted chip capacitor for medical implantable devices and method of manufacture therefor
US5836987A (en) 1995-11-15 1998-11-17 Cardiac Pacemakers, Inc. Apparatus and method for optimizing cardiac performance by determining the optimal timing interval from an accelerometer signal
US5697959A (en) 1996-01-11 1997-12-16 Pacesetter, Inc. Method and system for analyzing and displaying complex pacing event records
US5683431A (en) 1996-03-27 1997-11-04 Medtronic, Inc. Verification of capture by sensing evoked response across cardioversion electrodes
US5895414A (en) 1996-04-19 1999-04-20 Sanchez-Zambrano; Sergio Pacemaker housing
US6496715B1 (en) 1996-07-11 2002-12-17 Medtronic, Inc. System and method for non-invasive determination of optimal orientation of an implantable sensing device
JP2000514682A (en) 1996-07-11 2000-11-07 メドトロニック・インコーポレーテッド Minimal invasive implantable device for monitoring physiological events
US6295470B1 (en) 1996-08-19 2001-09-25 The Mower Family Chf Treatment Irrevocable Trust Antitachycardial pacing
US5735882A (en) * 1996-11-25 1998-04-07 Sulzer Intermedics Inc. Cardiac stimulator with backup-mode self-recovery
US5803084A (en) 1996-12-05 1998-09-08 Olson; Charles Three dimensional vector cardiographic display and method for displaying same
US5683434A (en) 1996-12-06 1997-11-04 Pacesetter, Inc. Microstrip EMI shunt for an implantable medical device
US5779645A (en) 1996-12-17 1998-07-14 Pacesetter, Inc. System and method for waveform morphology comparison
US6607509B2 (en) 1997-12-31 2003-08-19 Medtronic Minimed, Inc. Insertion device for an insertion set and method of using the same
SE9700396D0 (en) 1997-02-05 1997-02-05 Pacesetter Ab Heart stimulating device
US5983138A (en) 1997-04-04 1999-11-09 Cardiac Pacemakers, Inc. Device and method for ventricular tracking and pacing
US5861013A (en) 1997-04-29 1999-01-19 Medtronic Inc. Peak tracking capture detection circuit and method
US5873898A (en) 1997-04-29 1999-02-23 Medtronic, Inc. Microprocessor capture detection circuit and method
US6147680A (en) 1997-06-03 2000-11-14 Koa T&T Corporation Touchpad with interleaved traces
US6128535A (en) 1997-12-05 2000-10-03 Cardiac Pacemakers, Inc. Automatic capture verification in multisite cardiac pacing
US6148230A (en) 1998-01-30 2000-11-14 Uab Research Foundation Method for the monitoring and treatment of spontaneous cardiac arrhythmias
US6016442A (en) 1998-03-25 2000-01-18 Cardiac Pacemakers, Inc. System for displaying cardiac arrhythmia data
US7158830B2 (en) 1998-05-08 2007-01-02 Cardiac Pacemakers, Inc. Method and apparatus for optimizing stroke volume during DDD resynchronization therapy using adjustable atrio-ventricular delays
US6144880A (en) 1998-05-08 2000-11-07 Cardiac Pacemakers, Inc. Cardiac pacing using adjustable atrio-ventricular delays
US7110817B2 (en) 1998-05-08 2006-09-19 Cardiac Pacemakers, Inc. Method and apparatus for optimizing ventricular synchrony during DDD resynchronization therapy using adjustable atrio-ventricular delays
US6026320A (en) 1998-06-08 2000-02-15 Cardiac Pacemakers, Inc. Heart rate variability as an indicator of exercise capacity
US6055454A (en) 1998-07-27 2000-04-25 Cardiac Pacemakers, Inc. Cardiac pacemaker with automatic response optimization of a physiologic sensor based on a second sensor
US6345201B1 (en) 1998-07-29 2002-02-05 Pacesetter, Inc. System and method for ventricular capture using far-field evoked response
US6434428B1 (en) 1998-07-29 2002-08-13 Pacesetter, Inc. System and method for optimizing far-field R-wave sensing by switching electrode polarity during atrial capture verification
US6101416A (en) 1998-07-29 2000-08-08 Pacesetter, Inc. System and method for atrial autocapture in single-chamber pacemaker modes using far-field detection
US6424234B1 (en) 1998-09-18 2002-07-23 Greatbatch-Sierra, Inc. Electromagnetic interference (emi) filter and process for providing electromagnetic compatibility of an electronic device while in the presence of an electromagnetic emitter operating at the same frequency
US6163724A (en) 1998-09-18 2000-12-19 Medtronic, Inc. Microprocessor capture detection circuit and method
US6148234A (en) 1998-09-28 2000-11-14 Medtronic Inc. Dual site pacing system with automatic pulse output adjustment
US6227072B1 (en) 1998-10-02 2001-05-08 Ritchey Designs, Inc. Light weight bicycle pedal
US6044298A (en) 1998-10-13 2000-03-28 Cardiac Pacemakers, Inc. Optimization of pacing parameters based on measurement of integrated acoustic noise
US6415174B1 (en) 1998-11-09 2002-07-02 Board Of Regents The University Of Texas System ECG derived respiratory rhythms for improved diagnosis of sleep apnea
US6169921B1 (en) 1998-12-08 2001-01-02 Cardiac Pacemakers, Inc. Autocapture determination for an implantable cardioverter defibrillator
US6049730A (en) 1998-12-28 2000-04-11 Flaga Hf Method and apparatus for improving the accuracy of interpretation of ECG-signals
US6466820B1 (en) 1998-12-29 2002-10-15 Medtronic, Inc. Multi-site cardiac pacing system having trigger pace window
US6324427B1 (en) 1999-01-26 2001-11-27 Pacesetter, Inc. Implantable cardiac stimulation device having T-wave discrimination of fusion events during autocapture/autothreshold assessment
US6266554B1 (en) 1999-02-12 2001-07-24 Cardiac Pacemakers, Inc. System and method for classifying cardiac complexes
US6084253A (en) 1999-03-01 2000-07-04 Teccor Electronics, Lp Low voltage four-layer device with offset buried region
US6038474A (en) 1999-03-02 2000-03-14 Cardiac Pacemakers, Inc. Pseudo-fusion management during automatic capture verification
US6438409B1 (en) 1999-03-25 2002-08-20 Medtronic, Inc. Methods of characterizing ventricular operations and applications thereof
US6115628A (en) 1999-03-29 2000-09-05 Medtronic, Inc. Method and apparatus for filtering electrocardiogram (ECG) signals to remove bad cycle information and for use of physiologic signals determined from said filtered ECG signals
US6324421B1 (en) 1999-03-29 2001-11-27 Medtronic, Inc. Axis shift analysis of electrocardiogram signal parameters especially applicable for multivector analysis by implantable medical devices, and use of same
US6175766B1 (en) 1999-03-30 2001-01-16 Pacesetter, Inc. Cardiac pacemaker autothreshold arrangement and method with reliable capture
US6267778B1 (en) * 1999-04-12 2001-07-31 Fred Michael Cohen Pacing systems for treating functional ventricular conduction abnormalities of intrinsic origin
US6192275B1 (en) 1999-05-11 2001-02-20 Cardiac Pacemakers, Inc. Adaptive evoked response sensing for automatic capture verification
US6226551B1 (en) 1999-05-11 2001-05-01 Cardiac Pacemakers, Inc. Wide-band evoked response sensing for capture verification
WO2000069517A1 (en) 1999-05-12 2000-11-23 Medtronic, Inc. Monitoring apparatus using wavelet transforms for the analysis of heart rhythms
US6285907B1 (en) 1999-05-21 2001-09-04 Cardiac Pacemakers, Inc. System providing ventricular pacing and biventricular coordination
US6270457B1 (en) 1999-06-03 2001-08-07 Cardiac Intelligence Corp. System and method for automated collection and analysis of regularly retrieved patient information for remote patient care
US6312378B1 (en) 1999-06-03 2001-11-06 Cardiac Intelligence Corporation System and method for automated collection and analysis of patient information retrieved from an implantable medical device for remote patient care
US6449503B1 (en) 1999-07-14 2002-09-10 Cardiac Pacemakers, Inc. Classification of supraventricular and ventricular cardiac rhythms using cross channel timing algorithm
US6221011B1 (en) 1999-07-26 2001-04-24 Cardiac Intelligence Corporation System and method for determining a reference baseline of individual patient status for use in an automated collection and analysis patient care system
US6706022B1 (en) * 1999-07-27 2004-03-16 Alaris Medical Systems, Inc. Needleless medical connector with expandable valve mechanism
US6418340B1 (en) 1999-08-20 2002-07-09 Cardiac Pacemakers, Inc. Method and system for identifying and displaying groups of cardiac arrhythmic episodes
US7127290B2 (en) 1999-10-01 2006-10-24 Cardiac Pacemakers, Inc. Cardiac rhythm management systems and methods predicting congestive heart failure status
US6459929B1 (en) 1999-11-04 2002-10-01 Cardiac Pacemakers, Inc. Implantable cardiac rhythm management device for assessing status of CHF patients
US6491639B1 (en) 1999-11-10 2002-12-10 Pacesetter, Inc. Extravascular hemodynamic sensor
US6409675B1 (en) 1999-11-10 2002-06-25 Pacesetter, Inc. Extravascular hemodynamic monitor
US6480733B1 (en) 1999-11-10 2002-11-12 Pacesetter, Inc. Method for monitoring heart failure
US6368284B1 (en) 1999-11-16 2002-04-09 Cardiac Intelligence Corporation Automated collection and analysis patient care system and method for diagnosing and monitoring myocardial ischemia and outcomes thereof
US6336903B1 (en) 1999-11-16 2002-01-08 Cardiac Intelligence Corp. Automated collection and analysis patient care system and method for diagnosing and monitoring congestive heart failure and outcomes thereof
US6440066B1 (en) 1999-11-16 2002-08-27 Cardiac Intelligence Corporation Automated collection and analysis patient care system and method for ordering and prioritizing multiple health disorders to identify an index disorder
US6398728B1 (en) 1999-11-16 2002-06-04 Cardiac Intelligence Corporation Automated collection and analysis patient care system and method for diagnosing and monitoring respiratory insufficiency and outcomes thereof
US6505071B1 (en) 1999-12-15 2003-01-07 Cardiac Pacemakers, Inc. Cardiac management device with capability of noise detection in automatic capture verification
US6282440B1 (en) 1999-12-31 2001-08-28 Ge Marquette Medical Systems, Inc. Method to identify electrode placement
US6477422B1 (en) 2000-03-22 2002-11-05 Medtronic, Inc. Method and apparatus for capture detection
IL135335A (en) 2000-03-29 2013-12-31 Lycored Natural Prod Ind Ltd Use of carotenoids in the preparation of medicaments for preventing hormone induced adverse effects and pharmaceutical compositions comprising carotenoids
US6371922B1 (en) 2000-04-07 2002-04-16 Cardiac Pacemakers, Inc. Method for measuring baroreflex sensitivity and therapy optimization in heart failure patients
US6456880B1 (en) 2000-05-01 2002-09-24 Pacesetter, Inc. Implantable cardiac stimulation device for and method of monitoring progression or regression of a patient's heart condition by monitoring ventricular repolarization interval dispersion
US6512953B2 (en) 2000-05-11 2003-01-28 Pacesetter, Inc. System and method for automatically verifying capture during multi-chamber stimulation
US6618619B1 (en) 2000-05-12 2003-09-09 Pacesetter, Inc. Method and apparatus for reducing the effect of evoked responses on polarization measurements in an automatic capture pacing system
US6615082B1 (en) 2000-05-15 2003-09-02 Pacesetter, Inc. Method and device for optimally altering stimulation energy to maintain capture of cardiac tissue
US6389308B1 (en) 2000-05-30 2002-05-14 Vladimir Shusterman System and device for multi-scale analysis and representation of electrocardiographic data
US6424865B1 (en) 2000-07-13 2002-07-23 Cardiac Pacemakers, Inc. Ventricular conduction delay trending system and method
US6456881B1 (en) 2000-08-02 2002-09-24 Pacesetter, Inc. System and method of identifying fusion for dual-chamber automatic capture stimulation device
ATE414468T1 (en) 2000-08-03 2008-12-15 Draeger Medical Systems Inc ELECTROCARDIOLOGICAL SYSTEM FOR SYNTHESIZING LEADS AND DELIVERING AN ACCURATE MEASUREMENT
GB2370509A (en) 2000-08-29 2002-07-03 Don Edward Casey Subcutaneously implanted photovoltaic power supply
US20020035377A1 (en) 2000-09-18 2002-03-21 Cameron Health, Inc. Subcutaneous electrode for transthoracic conduction with insertion tool
US7149575B2 (en) 2000-09-18 2006-12-12 Cameron Health, Inc. Subcutaneous cardiac stimulator device having an anteriorly positioned electrode
US6866044B2 (en) 2000-09-18 2005-03-15 Cameron Health, Inc. Method of insertion and implantation of implantable cardioverter-defibrillator canisters
US20020035378A1 (en) 2000-09-18 2002-03-21 Cameron Health, Inc. Subcutaneous electrode for transthoracic conduction with highly maneuverable insertion tool
US7120495B2 (en) 2000-09-18 2006-10-10 Cameron Health, Inc. Flexible subcutaneous implantable cardioverter-defibrillator
US6954670B2 (en) 2001-11-05 2005-10-11 Cameron Health, Inc. Simplified defibrillator output circuit
US20020107544A1 (en) 2000-09-18 2002-08-08 Cameron Health, Inc. Current waveform for anti-bradycardia pacing for a subcutaneous implantable cardioverter-defibrillator
US7043299B2 (en) 2000-09-18 2006-05-09 Cameron Health, Inc. Subcutaneous implantable cardioverter-defibrillator employing a telescoping lead
US7065407B2 (en) 2000-09-18 2006-06-20 Cameron Health, Inc. Duckbill-shaped implantable cardioverter-defibrillator canister and method of use
US7194302B2 (en) 2000-09-18 2007-03-20 Cameron Health, Inc. Subcutaneous cardiac stimulator with small contact surface electrodes
US7090682B2 (en) 2000-09-18 2006-08-15 Cameron Health, Inc. Method and apparatus for extraction of a subcutaneous electrode
US6927721B2 (en) 2001-11-05 2005-08-09 Cameron Health, Inc. Low power A/D converter
US6952608B2 (en) 2001-11-05 2005-10-04 Cameron Health, Inc. Defibrillation pacing circuitry
US6950705B2 (en) 2000-09-18 2005-09-27 Cameron Health, Inc. Canister designs for implantable cardioverter-defibrillators
US6754528B2 (en) 2001-11-21 2004-06-22 Cameraon Health, Inc. Apparatus and method of arrhythmia detection in a subcutaneous implantable cardioverter/defibrillator
US7194309B2 (en) 2000-09-18 2007-03-20 Cameron Health, Inc. Packaging technology for non-transvenous cardioverter/defibrillator devices
US7146212B2 (en) 2000-09-18 2006-12-05 Cameron Health, Inc. Anti-bradycardia pacing for a subcutaneous implantable cardioverter-defibrillator
US20020095184A1 (en) 2000-09-18 2002-07-18 Bardy Gust H. Monophasic waveform for anti-tachycardia pacing for a subcutaneous implantable cardioverter-defibrillator
US20020035381A1 (en) 2000-09-18 2002-03-21 Cameron Health, Inc. Subcutaneous electrode with improved contact shape for transthoracic conduction
US7069080B2 (en) 2000-09-18 2006-06-27 Cameron Health, Inc. Active housing and subcutaneous electrode cardioversion/defibrillating system
US7039465B2 (en) 2000-09-18 2006-05-02 Cameron Health, Inc. Ceramics and/or other material insulated shell for active and non-active S-ICD can
US6788974B2 (en) 2000-09-18 2004-09-07 Cameron Health, Inc. Radian curve shaped implantable cardioverter-defibrillator canister
US6865417B2 (en) 2001-11-05 2005-03-08 Cameron Health, Inc. H-bridge with sensing circuit
US6952610B2 (en) 2000-09-18 2005-10-04 Cameron Health, Inc. Current waveforms for anti-tachycardia pacing for a subcutaneous implantable cardioverter- defibrillator
US6856835B2 (en) 2000-09-18 2005-02-15 Cameron Health, Inc. Biphasic waveform for anti-tachycardia pacing for a subcutaneous implantable cardioverter-defibrillator
US6988003B2 (en) 2000-09-18 2006-01-17 Cameron Health, Inc. Implantable cardioverter-defibrillator having two spaced apart shocking electrodes on housing
US6834204B2 (en) 2001-11-05 2004-12-21 Cameron Health, Inc. Method and apparatus for inducing defibrillation in a patient using a T-shock waveform
US20020035379A1 (en) 2000-09-18 2002-03-21 Bardy Gust H. Subcutaneous electrode for transthoracic conduction with improved installation characteristics
US6937907B2 (en) 2000-09-18 2005-08-30 Cameron Health, Inc. Subcutaneous electrode for transthoracic conduction with low-profile installation appendage and method of doing same
US7076296B2 (en) 2000-09-18 2006-07-11 Cameron Health, Inc. Method of supplying energy to subcutaneous cardioverter-defibrillator and pacer
US6778860B2 (en) 2001-11-05 2004-08-17 Cameron Health, Inc. Switched capacitor defibrillation circuit
US6725085B2 (en) 2000-09-22 2004-04-20 Armin Schwartzman Method and apparatus for characterizing cardiac tissue from local electrograms
US6631290B1 (en) 2000-10-25 2003-10-07 Medtronic, Inc. Multilayer ceramic electrodes for sensing cardiac depolarization signals
US6522915B1 (en) 2000-10-26 2003-02-18 Medtronic, Inc. Surround shroud connector and electrode housings for a subcutaneous electrode array and leadless ECGS
US6512940B1 (en) 2000-10-31 2003-01-28 Medtronic, Inc. Subcutaneous spiral electrode for sensing electrical signals of the heart
JP3725418B2 (en) 2000-11-01 2005-12-14 インターナショナル・ビジネス・マシーンズ・コーポレーション Signal separation method, image processing apparatus, and storage medium for restoring multidimensional signal from image data mixed with a plurality of signals
JP4028680B2 (en) 2000-11-01 2007-12-26 インターナショナル・ビジネス・マシーンズ・コーポレーション Signal separation method for restoring original signal from observation data, signal processing device, mobile terminal device, and storage medium
US6944495B2 (en) 2000-11-10 2005-09-13 C.R. Bard, Inc. Methods for processing electrocardiac signals having superimposed complexes
US6505067B1 (en) 2000-11-22 2003-01-07 Medtronic, Inc. System and method for deriving a virtual ECG or EGM signal
WO2002041946A2 (en) 2000-11-22 2002-05-30 Medtronic, Inc. Apparatus for detecting and treating ventricular arrhythmia
US6754523B2 (en) 2000-11-28 2004-06-22 J. Gerald Toole Method of analysis of the electrocardiogram
US6564106B2 (en) 2000-12-13 2003-05-13 Medtronic, Inc. Thin film electrodes for sensing cardiac depolarization signals
US6567701B2 (en) 2000-12-21 2003-05-20 Medtronic, Inc. Method and system for discriminating captured beats from non-captured beats in a cardiac pacing system
US7181285B2 (en) 2000-12-26 2007-02-20 Cardiac Pacemakers, Inc. Expert system and method
DE10128982A1 (en) 2001-01-17 2002-07-18 Biotronik Mess & Therapieg Pacemaker for stimulating a heart has a stimulation unit emitting electric impulses to stimulate bodily tissue and an evaluatory unit to record electric signals with these impulses and assess success levels of stimulation.
US6609027B2 (en) 2001-02-23 2003-08-19 Pacesetter, Inc. His Bundle sensing device and associated method
US6597951B2 (en) 2001-03-16 2003-07-22 Cardiac Pacemakers, Inc. Automatic selection from multiple cardiac optimization protocols
US6993389B2 (en) 2001-03-30 2006-01-31 Cardiac Pacemakers, Inc. Identifying heart failure patients suitable for resynchronization therapy using QRS complex width from an intracardiac electrogram
US6658293B2 (en) 2001-04-27 2003-12-02 Medtronic, Inc. Method and system for atrial capture detection based on far-field R-wave sensing
US6615083B2 (en) 2001-04-27 2003-09-02 Medtronic, Inc. Implantable medical device system with sensor for hemodynamic stability and method of use
US6654637B2 (en) 2001-04-30 2003-11-25 Medtronic, Inc. Method and system for ventricular fusion prevention
US6708058B2 (en) 2001-04-30 2004-03-16 Cardiac Pacemakers, Inc. Normal cardiac rhythm template generation system and method
US6622046B2 (en) 2001-05-07 2003-09-16 Medtronic, Inc. Subcutaneous sensing feedthrough/electrode assembly
US20030023175A1 (en) 2001-05-22 2003-01-30 Arzbaecher Robert C. Implantable cardiac arrest monitor and alarm system
US6456481B1 (en) 2001-05-31 2002-09-24 Greatbatch-Sierra, Inc. Integrated EMI filter-DC blocking capacitor
US7050851B2 (en) 2001-06-29 2006-05-23 Medtronic, Inc. Implantable cardioverter/defibrillator with housing electrode and lead detection and switching circuitry
EP1406541A4 (en) 2001-07-05 2010-01-13 Sigmed Inc System and method for separating cardiac signals
US6847839B2 (en) 2001-07-30 2005-01-25 The Trustees Of Columbia University In The City Of New York System and method for determining reentrant ventricular tachycardia isthmus location and shape for catheter ablation
EP1429839A2 (en) * 2001-08-28 2004-06-23 Medtronic, Inc. Implantable medical device for treating cardiac mechanical dysfunction by electrical stimulation
US7006869B2 (en) 2001-09-10 2006-02-28 Pacesetter, Inc. Method and device for enhanced capture tracking by discrimination of fusion beats
US7027861B2 (en) 2001-10-09 2006-04-11 Medtronic, Inc. Method and apparatus for affecting atrial defibrillation with bi-atrial pacing
US7113823B2 (en) 2001-10-26 2006-09-26 Cardiac Pacemakers, Inc. Morphology-based optimization of cardiac resynchronization therapy
US7286876B2 (en) 2001-10-26 2007-10-23 Cardiac Pacemakers, Inc. Template-based capture verification for multi-site pacing
US6871096B2 (en) 2001-10-26 2005-03-22 Medtronic, Inc. System and method for bi-ventricular fusion pacing
US7177689B2 (en) 2001-10-26 2007-02-13 Cardiac Pacemakers, Inc. Method and apparatus for capture verification and threshold determination
US6760615B2 (en) 2001-10-31 2004-07-06 Medtronic, Inc. Method and apparatus for discriminating between tachyarrhythmias
US6766190B2 (en) 2001-10-31 2004-07-20 Medtronic, Inc. Method and apparatus for developing a vectorcardiograph in an implantable medical device
US6701170B2 (en) 2001-11-02 2004-03-02 Nellcor Puritan Bennett Incorporated Blind source separation of pulse oximetry signals
US6975904B1 (en) 2001-11-08 2005-12-13 Pacesetter, Inc. Modification of evoked response detection algorithm based on orientation and activity of patient
US6625490B1 (en) 2001-11-14 2003-09-23 Pacesetter, Inc. System and method of automatically adjusting sensing parameters based on temporal measurement of cardiac events
US6959214B2 (en) 2001-11-28 2005-10-25 Medtronic, Inc. Implantable medical device for measuring mechanical heart function
US6768923B2 (en) 2001-12-05 2004-07-27 Cardiac Pacemakers, Inc. Apparatus and method for ventricular pacing triggered by detection of early ventricular excitation
US6768924B2 (en) 2002-01-03 2004-07-27 Cardiac Pacemakers, Inc. Method and apparatus for capture verification based on propagated electrical activity
US6928324B2 (en) 2002-02-14 2005-08-09 Pacesetter, Inc. Stimulation device for sleep apnea prevention, detection and treatment
US6999817B2 (en) 2002-02-14 2006-02-14 Packsetter, Inc. Cardiac stimulation device including sleep apnea prevention and treatment
US7146206B2 (en) 2002-03-20 2006-12-05 Medtronic, Inc. Detection of cardiac arrhythmia using mathematical representation of standard ΔRR probability density histograms
US6885893B1 (en) 2002-03-25 2005-04-26 Pacesetter, Inc. Implantable stimulation device and method for performing inter-chamber conduction search and conduction time measurement
EP1350539B1 (en) 2002-04-03 2006-10-18 Osypka Medical GmbH Apparatus for automatic determination of hemodynamically optimal cardiac pacing parameter values
US6889079B2 (en) 2002-04-12 2005-05-03 Cardiac Pacemakers, Inc. Method and system for characterizing supraventricular rhythm during cardiac pacing
US7139610B2 (en) 2002-04-26 2006-11-21 Medtronic, Inc. Capture management in multi-site pacing
US7263399B2 (en) 2002-04-29 2007-08-28 Medtronic, Inc. Apparatus and methods for analysis of cardiac device stored episodes containing sensed signals and waveforms
US7228174B2 (en) 2002-04-29 2007-06-05 Medtronics, Inc. Algorithm for the automatic determination of optimal AV an VV intervals
US6881192B1 (en) 2002-06-12 2005-04-19 Pacesetter, Inc. Measurement of sleep apnea duration and evaluation of response therapies using duration metrics
US7117036B2 (en) 2002-06-27 2006-10-03 Pacesetter, Inc. Using activity-based rest disturbance as a metric of sleep apnea
US6925330B2 (en) 2002-07-10 2005-08-02 Pacesetter, Inc. Implantable medical device and method for detecting cardiac events without using of refractory or blanking periods
US6950702B2 (en) 2002-07-15 2005-09-27 Cardiac Pacemakers, Inc. Use of curvature based features for beat detection
US7085599B2 (en) 2002-10-23 2006-08-01 Cardiac Pacemakers, Inc. Characterization of supraventricular rhythm using collected cardiac beats
US7203543B2 (en) 2002-10-23 2007-04-10 Cardiac Pacemakers, Inc. Method and system for detecting capture using a coronary vein electrode
FR2847361B1 (en) 2002-11-14 2005-01-28 Ela Medical Sa DEVICE FOR ANALYZING A SIGNAL, IN PARTICULAR A PHYSIOLOGICAL SIGNAL SUCH AS AN ECG SIGNAL
US6884218B2 (en) 2002-12-09 2005-04-26 Charles W. Olson Three dimensional vector cardiograph and method for detecting and monitoring ischemic events
SE0203728D0 (en) 2002-12-16 2002-12-16 St Jude Medical An Implantable heart stimulating device, a system including such a device and use of the system
SE0203724D0 (en) 2002-12-16 2002-12-16 St Jude Medical A cardiac stimulating device
US7191004B2 (en) 2002-12-31 2007-03-13 Cardiac Pacemakers, Inc. Capture verification using an evoked response reference
US7013176B2 (en) 2003-01-28 2006-03-14 Cardiac Pacemakers, Inc. Method and apparatus for setting pacing parameters in cardiac resynchronization therapy
US7103404B2 (en) 2003-02-27 2006-09-05 Medtronic,Inc. Detection of tachyarrhythmia termination
US7702388B2 (en) 2003-02-28 2010-04-20 Cardiac Pacemakers, Inc. Cardiac therapy triggered by capture verification
US6973350B1 (en) 2003-03-31 2005-12-06 Pacesetter, Inc. Diagnosis of atrial fusion, atrial pseudofusion and/or native atrial activity
FR2853427B1 (en) 2003-04-01 2005-06-17 Thales Sa METHOD OF BLINDLY IDENTIFYING MIXTURES OF SOURCES WITH HIGHER ORDERS
US20040215240A1 (en) 2003-04-11 2004-10-28 Lovett Eric G. Reconfigurable subcutaneous cardiac device
US7236819B2 (en) 2003-04-11 2007-06-26 Cardiac Pacemakers, Inc. Separation of a subcutaneous cardiac signal from a plurality of composite signals
US20040215277A1 (en) 2003-04-25 2004-10-28 Peter Oosterhoff Dynamic pacing interval extension for detection of intrinsic ventricular activity
US20040215276A1 (en) 2003-04-25 2004-10-28 Patrick Scholten Form analysis to detect evoked response
US7107093B2 (en) 2003-04-29 2006-09-12 Medtronic, Inc. Use of activation and recovery times and dispersions to monitor heart failure status and arrhythmia risk
US7477932B2 (en) 2003-05-28 2009-01-13 Cardiac Pacemakers, Inc. Cardiac waveform template creation, maintenance and use
US7129935B2 (en) 2003-06-02 2006-10-31 Synaptics Incorporated Sensor patterns for a capacitive sensing apparatus
SE0301800D0 (en) 2003-06-23 2003-06-23 St Jude Medical Evoked response detector
US20050038478A1 (en) 2003-08-11 2005-02-17 Klepfer Ruth N. Activation recovery interval for classification of cardiac beats in an implanted device
US7065400B2 (en) 2003-08-20 2006-06-20 Pacesetter, Inc. Method and apparatus for automatically programming CRT devices
US20050065587A1 (en) 2003-09-24 2005-03-24 Mark Gryzwa Implantable lead with magnetic jacket
US7684861B2 (en) 2003-11-13 2010-03-23 Cardiac Pacemakers, Inc. Implantable cardiac monitor upgradeable to pacemaker or cardiac resynchronization device
US7242978B2 (en) 2003-12-03 2007-07-10 Medtronic, Inc. Method and apparatus for generating a template for arrhythmia detection and electrogram morphology classification
US7319900B2 (en) 2003-12-11 2008-01-15 Cardiac Pacemakers, Inc. Cardiac response classification using multiple classification windows
US8521284B2 (en) 2003-12-12 2013-08-27 Cardiac Pacemakers, Inc. Cardiac response classification using multisite sensing and pacing
US7774064B2 (en) 2003-12-12 2010-08-10 Cardiac Pacemakers, Inc. Cardiac response classification using retriggerable classification windows
US7184835B2 (en) 2003-12-12 2007-02-27 Cardiac Pacemakers, Inc. Method and apparatus for adjustable AVD programming using a table
US7203540B2 (en) * 2003-12-22 2007-04-10 Cardiac Pacemakers, Inc. Method and system for setting cardiac resynchronization therapy parameters
US7123960B2 (en) 2003-12-22 2006-10-17 Cardiac Pacemakers, Inc. Method and system for delivering cardiac resynchronization therapy with variable atrio-ventricular delay
US7277754B2 (en) 2003-12-24 2007-10-02 Cardiac Pacemakers, Inc. Method and system for removing pacing artifacts from subcutaneous electrocardiograms
US7225021B1 (en) 2004-01-30 2007-05-29 Pacesetter, Inc. Differentiation of central sleep apnea and obstructive sleep apnea using an implantable cardiac device
US7299086B2 (en) 2004-03-05 2007-11-20 Cardiac Pacemakers, Inc. Wireless ECG in implantable devices
US7706866B2 (en) 2004-06-24 2010-04-27 Cardiac Pacemakers, Inc. Automatic orientation determination for ECG measurements using multiple electrodes
US7890159B2 (en) 2004-09-30 2011-02-15 Cardiac Pacemakers, Inc. Cardiac activation sequence monitoring and tracking
US7509170B2 (en) 2005-05-09 2009-03-24 Cardiac Pacemakers, Inc. Automatic capture verification using electrocardiograms sensed from multiple implanted electrodes
US7894893B2 (en) 2004-09-30 2011-02-22 Cardiac Pacemakers, Inc. Arrhythmia classification and therapy selection
US7228173B2 (en) 2004-11-23 2007-06-05 Cardiac Pacemakers, Inc. Cardiac tachyarrhythmia therapy selection based on patient response information
US7797036B2 (en) 2004-11-30 2010-09-14 Cardiac Pacemakers, Inc. Cardiac activation sequence monitoring for ischemia detection
US7933651B2 (en) 2004-11-23 2011-04-26 Cardiac Pacemakers, Inc. Cardiac template generation based on patient response information
US7457664B2 (en) 2005-05-09 2008-11-25 Cardiac Pacemakers, Inc. Closed loop cardiac resynchronization therapy using cardiac activation sequence information
US7805185B2 (en) 2005-05-09 2010-09-28 Cardiac Pacemakers, In. Posture monitoring using cardiac activation sequences
US7917196B2 (en) 2005-05-09 2011-03-29 Cardiac Pacemakers, Inc. Arrhythmia discrimination using electrocardiograms sensed from multiple implanted electrodes
US7761162B2 (en) 2004-12-13 2010-07-20 Cardiac Pacemakers, Inc. Capture verification with intrinsic response discrimination
US7908006B2 (en) 2004-12-15 2011-03-15 Cardiac Pacemakers, Inc. Cardiac pacing response classification using an adaptable classification interval
US7818056B2 (en) 2005-03-24 2010-10-19 Cardiac Pacemakers, Inc. Blending cardiac rhythm detection processes
US7765004B2 (en) 2005-04-28 2010-07-27 Cardiac Pacemakers, Inc. Methods and systems for managing fusion and noise in cardiac pacing response classification
US7908001B2 (en) 2005-08-23 2011-03-15 Cardiac Pacemakers, Inc. Automatic multi-level therapy based on morphologic organization of an arrhythmia
US7653431B2 (en) 2005-12-20 2010-01-26 Cardiac Pacemakers, Inc. Arrhythmia discrimination based on determination of rate dependency
US8527048B2 (en) * 2006-06-29 2013-09-03 Cardiac Pacemakers, Inc. Local and non-local sensing for cardiac pacing
US20080004665A1 (en) 2006-06-29 2008-01-03 Mccabe Aaron R Determination of cardiac pacing parameters based on non-localized sensing
US7580741B2 (en) 2006-08-18 2009-08-25 Cardiac Pacemakers, Inc. Method and device for determination of arrhythmia rate zone thresholds using a probability function

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0560569A2 (en) * 1992-03-09 1993-09-15 Angemed, Inc. Fibrillation and tachycardia detection
WO2002040097A1 (en) * 2000-11-17 2002-05-23 St. Jude Medical Ab A cardiac stimulating device
WO2002047761A2 (en) * 2000-12-14 2002-06-20 Medtronic, Inc. Atrial aware vvi: a method for atrial synchronous ventricular (vdd/r) pacing using the subcutaneous electrode array and a standard pacing lead
US6993379B1 (en) * 2002-12-30 2006-01-31 Pacesetter, Inc. System and method for emulating a surface EKG using an implantable cardiac stimulation device
WO2005089865A1 (en) * 2004-03-17 2005-09-29 Medtronic, Inc. Apparatus and methods of energy efficient, atrial-based bi-ventricular fusion-pacing
EP1629863A1 (en) * 2004-08-27 2006-03-01 Pacesetter, Inc. System and method for determining optimal atrioventricular delay based on intrinsic conduction delays

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8983602B2 (en) 2007-08-07 2015-03-17 Cardiac Pacemakers, Inc. Method and apparatus to perform electrode combination selection
US9008775B2 (en) 2007-08-07 2015-04-14 Cardiac Pacemakers, Inc. Method and apparatus to perform electrode combination selection
US9427588B2 (en) 2007-08-07 2016-08-30 Cardiac Pacemakers, Inc. Method and apparatus to perform electrode combination selection
US9533160B2 (en) 2007-08-07 2017-01-03 Cardiac Pacemakers, Inc. Method and apparatus to perform electrode combination selection
US9539429B2 (en) 2007-08-07 2017-01-10 Cardiac Pacemakers, Inc. Method and apparatus to perform electrode combination selection

Also Published As

Publication number Publication date
JP2009542331A (en) 2009-12-03
EP2038007A2 (en) 2009-03-25
JP5184525B2 (en) 2013-04-17
WO2008005270A8 (en) 2008-06-05
WO2008005270A2 (en) 2008-01-10
EP2038007B1 (en) 2016-03-09
US8527048B2 (en) 2013-09-03
US20080009909A1 (en) 2008-01-10

Similar Documents

Publication Publication Date Title
WO2008005270A8 (en) Local and non-local sensing for cardiac pacing
WO2001087134A3 (en) Apparatus and method for controlling the delivery of non-excitatory cardiac contractility modulating signals to a heart
EP4241830A3 (en) Systems and methods for detecting nerve function
JP2022058814A5 (en)
WO2007095612A3 (en) Method and device for delivering anti-tachycardia pacing therapy
WO2007115104A3 (en) Method and apparatus for detecting arrhythmias in a medical device
WO2006119103A3 (en) Event-based lead impedance monitoring
JP2008534218A5 (en)
WO2009102613A3 (en) Methods of monitoring hemodynamic status for ryhthm discrimination within the heart
WO2007087192A3 (en) Device for detecting and treating depression
ATE387140T1 (en) SLEEP DETECTION USING ADJUSTABLE THRESHOLD VALUE
WO2006060426A3 (en) Method and apparatus for detecting left ventricular lead displacement based upon egm change
WO2004093651A3 (en) Processing pulse signal in conjunction with ecg signal to detect pulse in external defibrillation
ATE473781T1 (en) DEVICE FOR DETECTING ARRHYTHMIA IN A MEDICAL DEVICE
EP1690565A3 (en) Monitoring physiological signals during external electrical stimulation
JP2008514373A5 (en)
WO2007126578A3 (en) Hemodynamic stability assessment based on heart sounds
WO2009111764A3 (en) Accurate cardiac event detection in an implantable cardiac stimulus device
WO2014089143A3 (en) Apparatus for determining capture based on the determination whether a positive deflection of a sensed signal precedes a negative deflection of the signal
WO2007064790A3 (en) Cardiac pacemaker with dynamic conduction time monitoring
DE602005016383D1 (en) TIME SEQUENCE IN BIVENTRICULAR PACING IN PATIENTS WITH HEART INSUFFICIENCY
WO2009042030A3 (en) Neurostimulation systems for cardiac conditions
JP2007301401A5 (en)
WO2009051811A3 (en) System having wireless implantable sensor
EP1981588A4 (en) Implantable cardiac stimulator, device and system for monitoring the status of a cardiac lead

Legal Events

Date Code Title Description
WWE Wipo information: entry into national phase

Ref document number: 2009518259

Country of ref document: JP

NENP Non-entry into the national phase

Ref country code: DE

WWE Wipo information: entry into national phase

Ref document number: 2007809967

Country of ref document: EP

NENP Non-entry into the national phase

Ref country code: RU