WO2008014001A3 - Anatomical visualization and measurement system - Google Patents

Anatomical visualization and measurement system Download PDF

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Publication number
WO2008014001A3
WO2008014001A3 PCT/US2007/017040 US2007017040W WO2008014001A3 WO 2008014001 A3 WO2008014001 A3 WO 2008014001A3 US 2007017040 W US2007017040 W US 2007017040W WO 2008014001 A3 WO2008014001 A3 WO 2008014001A3
Authority
WO
WIPO (PCT)
Prior art keywords
blood vessel
mesh model
determining
stress
pixel
Prior art date
Application number
PCT/US2007/017040
Other languages
French (fr)
Other versions
WO2008014001A2 (en
Inventor
David T Chen
Jeff Dwyer
Mark F Fillinger
Steven P Marra
M Weston Chapman
Original Assignee
M2S Inc
David T Chen
Jeff Dwyer
Mark F Fillinger
Steven P Marra
M Weston Chapman
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by M2S Inc, David T Chen, Jeff Dwyer, Mark F Fillinger, Steven P Marra, M Weston Chapman filed Critical M2S Inc
Publication of WO2008014001A2 publication Critical patent/WO2008014001A2/en
Publication of WO2008014001A3 publication Critical patent/WO2008014001A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves 
    • A61B5/055—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves  involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/02007—Evaluating blood vessel condition, e.g. elasticity, compliance
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
    • A61B6/02—Devices for diagnosis sequentially in different planes; Stereoscopic radiation diagnosis
    • A61B6/03—Computerised tomographs
    • A61B6/032—Transmission computed tomography [CT]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/48—Diagnostic techniques
    • A61B8/483—Diagnostic techniques involving the acquisition of a 3D volume of data

Abstract

A method for determining the risk of rupture of a blood vessel using an appropriate set of 2-D slice images obtained by scanning the blood vessel, the method comprising: generating a mesh model of the blood vessel using the set of 2-D slice images; conducting finite element stress analysis on the mesh model to calculate the level of stress on different locations on the mesh model; and determining the risk of rupture of the blood vessel based on the calculated levels of stress on different locations on the mesh model. Apparatus for determining the risk of rupture of a blood vessel using an appropriate set of 2-D slice images obtained by scanning the blood vessel, the apparatus comprising: apparatus for generating a mesh model of the blood vessel using the set of 2-D slice images; apparatus for conducting finite element stress analysis on the mesh model to calculate the level of stress on different locations on the mesh model; and apparatus for determining the risk of rupture of the blood vessel based on the calculated levels of stress on different locations on the mesh model. A method for conducting virtual histology, wherein the method comprises using the Contiguous Element Defined Area (CEDA) method. A method for conducting virtual histology, wherein the method comprises: (a) determining the number of tissues (NT) to be characterized; (b) for each tissue Ti, defining two functions, one for inclusion (Ti) and one to measure spatial_coherence (Tj); (c) choosing an unlabeled pixel in the sample S and testing the pixel density for inclusion (Ti) - initially, all pixels within the sample are 'unlabelled' - if included, label the pixel with Ti, and recursively iterate through the unlabeled contiguous pixels until no more meet the inclusion criteria; (d) repeating Step (c) for each tissue Ti and each unlabeled pixel in the sample S; (e) for each set of found contiguous pixels, applying the criteria for spatial coherence, spatial_coherence(Tι) - if the set meets the criteria, preserve the labeling for Ti, otherwise re-labeling it as 'incoherent'; (f) optionally, re-labeling the 'incoherent' pixel sets as the tissues Ti found in the adjoining pixels; and (g) reporting virtual histology results using percentages and statistics derived using an explicit spatial coherence measure.
PCT/US2007/017040 2006-07-28 2007-07-30 Anatomical visualization and measurement system WO2008014001A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US83411006P 2006-07-28 2006-07-28
US60/834,110 2006-07-28

Publications (2)

Publication Number Publication Date
WO2008014001A2 WO2008014001A2 (en) 2008-01-31
WO2008014001A3 true WO2008014001A3 (en) 2009-04-09

Family

ID=38982142

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/017040 WO2008014001A2 (en) 2006-07-28 2007-07-30 Anatomical visualization and measurement system

Country Status (1)

Country Link
WO (1) WO2008014001A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2942941B1 (en) 2014-05-08 2016-04-27 Axis AB Method and apparatus for determining a need for a change in a pixel density requirement due to changing light conditions

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5151856A (en) * 1989-08-30 1992-09-29 Technion R & D Found. Ltd. Method of displaying coronary function
WO2006002353A2 (en) * 2004-06-23 2006-01-05 Medical Metrix Solutions, Inc Anatomical visualization and measurement system

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5151856A (en) * 1989-08-30 1992-09-29 Technion R & D Found. Ltd. Method of displaying coronary function
WO2006002353A2 (en) * 2004-06-23 2006-01-05 Medical Metrix Solutions, Inc Anatomical visualization and measurement system

Also Published As

Publication number Publication date
WO2008014001A2 (en) 2008-01-31

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