WO2008021242A3 - Fluorotaxoid-fatty acid conjugates and pharmaceutical compositions thereof - Google Patents

Fluorotaxoid-fatty acid conjugates and pharmaceutical compositions thereof Download PDF

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Publication number
WO2008021242A3
WO2008021242A3 PCT/US2007/017806 US2007017806W WO2008021242A3 WO 2008021242 A3 WO2008021242 A3 WO 2008021242A3 US 2007017806 W US2007017806 W US 2007017806W WO 2008021242 A3 WO2008021242 A3 WO 2008021242A3
Authority
WO
WIPO (PCT)
Prior art keywords
fluorotaxoid
fatty acid
pharmaceutical compositions
acid conjugates
conjugates
Prior art date
Application number
PCT/US2007/017806
Other languages
French (fr)
Other versions
WO2008021242A2 (en
Inventor
Iwao Ojima
Original Assignee
Univ New York State Res Found
Iwao Ojima
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ New York State Res Found, Iwao Ojima filed Critical Univ New York State Res Found
Publication of WO2008021242A2 publication Critical patent/WO2008021242A2/en
Publication of WO2008021242A3 publication Critical patent/WO2008021242A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/12—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)

Abstract

The invention relates to fluorotaxoid-fatty acid conjugates and pharmaceutical compositions thereof. The conjugates have the following formula:
PCT/US2007/017806 2006-08-10 2007-08-10 Fluorotaxoid-fatty acid conjugates and pharmaceutical compositions thereof WO2008021242A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US82196706P 2006-08-10 2006-08-10
US60/821,967 2006-08-10

Publications (2)

Publication Number Publication Date
WO2008021242A2 WO2008021242A2 (en) 2008-02-21
WO2008021242A3 true WO2008021242A3 (en) 2008-07-03

Family

ID=39082637

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/017806 WO2008021242A2 (en) 2006-08-10 2007-08-10 Fluorotaxoid-fatty acid conjugates and pharmaceutical compositions thereof

Country Status (1)

Country Link
WO (1) WO2008021242A2 (en)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5795909A (en) * 1996-05-22 1998-08-18 Neuromedica, Inc. DHA-pharmaceutical agent conjugates of taxanes
US6080877A (en) * 1996-05-22 2000-06-27 Neuromedica, Inc. Taxanes
US6576636B2 (en) * 1996-05-22 2003-06-10 Protarga, Inc. Method of treating a liver disorder with fatty acid-antiviral agent conjugates
WO2005041881A2 (en) * 2003-10-30 2005-05-12 The Research Foundation Of State University Of New York Taxoid-fatty acid conjugates and pharmaceutical compositions thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5795909A (en) * 1996-05-22 1998-08-18 Neuromedica, Inc. DHA-pharmaceutical agent conjugates of taxanes
US6080877A (en) * 1996-05-22 2000-06-27 Neuromedica, Inc. Taxanes
US6576636B2 (en) * 1996-05-22 2003-06-10 Protarga, Inc. Method of treating a liver disorder with fatty acid-antiviral agent conjugates
WO2005041881A2 (en) * 2003-10-30 2005-05-12 The Research Foundation Of State University Of New York Taxoid-fatty acid conjugates and pharmaceutical compositions thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
KUZNETSOVA L.: "Syntheses and evaluation of novel fatty acid-second-generation taxoid conjugates as promising anticancer agents", BIOORGANIC & MEDICINAL CHEMISTRY, vol. 16, 2006, pages 974 - 977, XP025106422, DOI: doi:10.1016/j.bmcl.2005.10.089 *

Also Published As

Publication number Publication date
WO2008021242A2 (en) 2008-02-21

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