WO2008023266A3 - Kiwi extract - Google Patents

Kiwi extract Download PDF

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Publication number
WO2008023266A3
WO2008023266A3 PCT/IB2007/003265 IB2007003265W WO2008023266A3 WO 2008023266 A3 WO2008023266 A3 WO 2008023266A3 IB 2007003265 W IB2007003265 W IB 2007003265W WO 2008023266 A3 WO2008023266 A3 WO 2008023266A3
Authority
WO
WIPO (PCT)
Prior art keywords
kiwi extract
extract
human
mediated
isolation
Prior art date
Application number
PCT/IB2007/003265
Other languages
French (fr)
Other versions
WO2008023266A2 (en
Inventor
Thomas Eidenberger
Original Assignee
Gmbh Omnica
Thomas Eidenberger
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gmbh Omnica, Thomas Eidenberger filed Critical Gmbh Omnica
Priority to EP07825529A priority Critical patent/EP2018176A2/en
Priority to JP2009508546A priority patent/JP5290158B2/en
Priority to CN2007800161961A priority patent/CN101522204B/en
Publication of WO2008023266A2 publication Critical patent/WO2008023266A2/en
Publication of WO2008023266A3 publication Critical patent/WO2008023266A3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4875Compounds of unknown constitution, e.g. material from plants or animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10Laxatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12Antidiarrhoeals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Abstract

The invention describes the preparation, isolation and use of an extract of kiwi fruit for the treatment of a disease or condition related with, caused by or mediated by activity of human pancreatic lipase and/or human fatty acid synthase.
PCT/IB2007/003265 2006-05-05 2007-04-27 Kiwi extract WO2008023266A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP07825529A EP2018176A2 (en) 2006-05-05 2007-04-27 Kiwi extract
JP2009508546A JP5290158B2 (en) 2006-05-05 2007-04-27 Kiwi extract
CN2007800161961A CN101522204B (en) 2006-05-05 2007-04-27 Kiwi extract

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
AT0077806A AT503521A1 (en) 2006-05-05 2006-05-05 USE OF AN EXTRACT OF KIWI FRUIT
ATAT778/2006 2006-05-05
US11/740,583 US7862840B2 (en) 2006-05-05 2007-04-26 Kiwi extract
US11/740,583 2007-04-26

Publications (2)

Publication Number Publication Date
WO2008023266A2 WO2008023266A2 (en) 2008-02-28
WO2008023266A3 true WO2008023266A3 (en) 2009-04-09

Family

ID=38654823

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2007/003265 WO2008023266A2 (en) 2006-05-05 2007-04-27 Kiwi extract

Country Status (6)

Country Link
US (1) US7862840B2 (en)
EP (1) EP2018176A2 (en)
JP (1) JP5290158B2 (en)
CN (1) CN101522204B (en)
AT (1) AT503521A1 (en)
WO (1) WO2008023266A2 (en)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101014004B1 (en) * 2008-06-30 2011-02-14 한국 한의학 연구원 Compositions and functional food for prevention and treatment of obesity
FR2933871B1 (en) * 2008-07-18 2012-12-14 Yvery FORMULATION FOR IMPROVING THE BIOAVAILABILITY OF A HYDROPHOBIC MOLECULE
ITRM20080563A1 (en) * 2008-10-22 2010-04-23 Univ Catania NEW COAGULANT AGENTS OF VEGETABLE ORIGIN AND RELATED USES.
GB0819958D0 (en) * 2008-10-31 2008-12-10 Provexis Natural Products Ltd Therapeutic compositions
GB0819959D0 (en) 2008-10-31 2008-12-10 Provexis Natural Products Ltd Fruit extracts
MX2009008889A (en) * 2009-08-20 2009-10-15 Biokab S A De C V Phytoceutic compositions for pets.
JP2011207796A (en) * 2010-03-29 2011-10-20 Iwate Univ Chaenomeles sinensis derived polyphenol having lipid metabolism improving function
EP2566853B1 (en) 2010-05-05 2017-01-25 Infinity Pharmaceuticals, Inc. Tetrazolones as inhibitors of fatty acid synthase
EP2648741B1 (en) 2010-12-07 2015-12-02 University Of Oslo Cardio-protective agents from kiwifruits
CN103619344B (en) * 2011-05-16 2017-09-12 维特食品加工有限公司 Dietary supplements
AU2013222577A1 (en) * 2012-02-21 2014-09-18 University Of Oslo Cardio-protective agents from kiwifruits
EP2844083B1 (en) 2012-04-23 2018-07-25 University Of Oslo Use of tomato extract as antihypertensive agent and process for making water soluble sugar free tomato extract
US20140116916A1 (en) * 2012-10-31 2014-05-01 2294719 Ontario Limited Therapy for Constipation
GB201223365D0 (en) 2012-12-24 2013-02-06 Provexis Natural Products Ltd Compositions
CN103705620B (en) * 2013-12-18 2016-03-30 广东省农业科学院蚕业与农产品加工研究所 The preparation method of indissoluble combined state polyphenol in a kind of Fructus Litchi
CN103709206B (en) * 2013-12-26 2015-12-30 长沙市博泰生物科技有限公司 A kind of preparation method of Actinidin
US9526768B2 (en) * 2014-11-13 2016-12-27 Jennifer Mai Compositions for the treatment of cancer
NZ732197A (en) * 2014-11-28 2022-07-01 Anagenix Ip Ltd Gold kiwifruit compositions and methods of preparation and use therefor
CA3042720A1 (en) 2016-11-02 2018-05-11 Provexis Natural Products Limited Water soluble tomato extract protects against adverse effects of air pollution
CN107621456A (en) * 2017-09-12 2018-01-23 合肥师范学院 A kind of kiwi polyphenol content assaying method
US20200315998A1 (en) * 2017-12-27 2020-10-08 Suntory Holdings Limited Composition for improving intestinal barrier function
CN109045006B (en) * 2018-07-20 2020-12-04 山东省千佛山医院 Pharmaceutical composition for preventing and treating vascular embolic diseases
MY197227A (en) * 2018-08-17 2023-06-06 Malaysian Palm Oil Board Mpob Composition comprising oil palm phenolics for use in the treatment and prevention of colon diseases and for promoting and maintaining gut and general health
KR102169239B1 (en) * 2018-11-30 2020-10-23 이스트힐(주) Composition for skin anti-wrinkle comprising maslinic derivatives
CN110496144A (en) * 2019-08-14 2019-11-26 右江民族医学院 A kind of Kiwi extract preparation method and its application for preventing and treating cardiovascular and cerebrovascular disease
US20210322500A1 (en) * 2020-02-04 2021-10-21 Waitaki Biosciences Method for producing stable actinidia deliciosa powder with high level bioactive actinidin enzyme
JPWO2023112973A1 (en) * 2021-12-14 2023-06-22

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02202808A (en) * 1989-01-31 1990-08-10 Ichimaru Pharcos Co Ltd Extract solution of kiwi fruit or concentrated extract of the same solution
JPH06256207A (en) * 1991-09-06 1994-09-13 Yoko Fukuya Anti-mutagen substance, antiviral substance and cell growth promoting substance
JP2002293780A (en) * 2001-03-30 2002-10-09 Sakamoto Koryo Kk Kiwi catechin and method for producing the same
WO2004017982A1 (en) * 2002-08-23 2004-03-04 Pangenomics Co., Ltd Composition comprising the extract of actinidia arguta and related species for the prevention and treatment of allergic disease and non-allergic inflammatory disease
KR20040097716A (en) * 2003-05-13 2004-11-18 주식회사 팬제노믹스 Health food comprising the extract of Actinidia arguta for preventing and improving baldness disorders and seborrheic skin disorders

Family Cites Families (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5087240A (en) * 1983-08-18 1992-02-11 Drug Delivery Systems Inc. Transdermal drug patch with conductive fibers
US4921475A (en) * 1983-08-18 1990-05-01 Drug Delivery Systems Inc. Transdermal drug patch with microtubes
JPS61140510A (en) 1984-12-13 1986-06-27 Junichi Udagawa Preparation of kiwi fruit solution
US5163899A (en) * 1987-03-20 1992-11-17 Drug Delivery Systems Inc. Transdermal drug delivery system
US5312325A (en) * 1987-05-28 1994-05-17 Drug Delivery Systems Inc Pulsating transdermal drug delivery system
JP2691985B2 (en) 1987-08-04 1997-12-17 ファナック 株式会社 Robot trajectory control method
GB8804164D0 (en) * 1988-02-23 1988-03-23 Tucker J M Bandage for administering physiologically active compound
JPH0272850A (en) 1988-09-06 1990-03-13 Ehime Pref Gov Seika Nogyo Kyodo Kumiai Rengokai Production of clear kiwi fruit juice
US5008110A (en) * 1988-11-10 1991-04-16 The Procter & Gamble Company Storage-stable transdermal patch
US5088977A (en) * 1988-12-21 1992-02-18 Drug Delivery Systems Inc. Electrical transdermal drug applicator with counteractor and method of drug delivery
IT1232357B (en) * 1989-05-16 1992-01-28 Stazione Sperimentale Per L In PROTEIN INHIBITOR OF PECTINESTERASE AND ITS USE IN THE PREPARATION OF FRUIT JUICES AND VEGETABLES
NZ235205A (en) 1989-09-07 1992-04-28 Commw Scient Ind Res Org Producing chlorophyll and other fractions from kiwifruit
CA2031376A1 (en) * 1989-12-04 1991-06-05 Bahram Farhadieh Single layer transdermal drug administration system
JPH04278063A (en) * 1991-03-05 1992-10-02 Nippon Oil & Fats Co Ltd Method for softening edible meat
US5352456A (en) * 1991-10-10 1994-10-04 Cygnus Therapeutic Systems Device for administering drug transdermally which provides an initial pulse of drug
DE69228827T2 (en) * 1991-12-18 1999-10-21 Minnesota Mining & Mfg MULTI-LAYER LOCK STRUCTURES
EP0553769B1 (en) 1992-01-29 1996-01-03 FRANZ VÖLKL GmbH & CO. SKI UND TENNIS SPORTARTIKELFABRIK KG Racket, particularly tennis racket
JP3521155B2 (en) * 1993-12-06 2004-04-19 ニッカウヰスキー株式会社 Method for producing fruit polyphenols
JPH09291039A (en) * 1995-12-26 1997-11-11 Suntory Ltd Antiobestic medicine comprising procyanidin as active ingredient
CN1067258C (en) 1996-10-30 2001-06-20 浙江中医学院 Medicinal preparation with extractive from yangtao root and preparing process thereof
JP4331282B2 (en) 1998-03-04 2009-09-16 花王株式会社 Integrin expression promoter
AT407821B (en) * 1998-03-24 2001-06-25 Franz Dr Stueckler MEDIUM BASED ON NATURAL SUBSTANCES
EP0953296A1 (en) * 1998-05-02 1999-11-03 Societe Des Produits Nestle S.A. Method for producing a kiwi juice
JP2001151696A (en) 1999-11-22 2001-06-05 Keiko Tanaka Agent which is obtained from actinidine and is used for removing protein cell different from enzyme for inhibiting proliferation and metastasis of tumor
CA2409643C (en) 2000-03-21 2013-10-01 Bruce William Donaldson Improvements in and relating to digestive/laxative compositions
KR20010096881A (en) 2000-04-15 2001-11-08 김영호 Anti-tumorous extract and chlorophyll derivative isolated from Actinidia arguta
SE0002691D0 (en) * 2000-07-17 2000-07-17 Maarten Hansson Embedded commands in digital images
US6991812B2 (en) * 2000-09-05 2006-01-31 Kao Corporation Agent for preventing, improving or treating hypertension
CN100436589C (en) * 2001-06-22 2008-11-26 印度技术研究院 Process for preparation of gallic acid by co-culture
US6580967B2 (en) 2001-06-26 2003-06-17 Applied Materials, Inc. Method for providing distributed material management and flow control in an integrated circuit factory
JP2003061615A (en) 2001-08-27 2003-03-04 Niigata Prefecture Telomerase inhibitor and food composition
US8143062B2 (en) * 2001-11-30 2012-03-27 Hirsch Alan R Method and composition for enhancing weight loss
JP2003171294A (en) 2001-12-04 2003-06-17 Nof Corp Thrombogenesis suppressing agent and composition containing the same
CN1362025A (en) 2002-01-15 2002-08-07 湖南老爹农业科技开发股份有限公司 Yangtao kernel oil capsule
FR2836336B1 (en) * 2002-02-26 2004-08-27 Diana Ingredients USE IN A COSMETIC TREATMENT OF A PHENOLIC FRACTION RICH IN DIHYDROCHALCONES
US20030045473A1 (en) * 2002-07-19 2003-03-06 Sarama Robert Joseph Compositions, kits, and methods for cardiovascular health
KR20040080640A (en) 2003-03-12 2004-09-20 주식회사 한국토종약초연구소 Pharmaceutical composition comprising a fruit extract of Actinidia polygama AP having anti-gout activity
CN1539986A (en) 2003-04-27 2004-10-27 戴向东 Method for extracting composite polysaccharide AVDS possessing anticarcinogenesis from 'mao renshen' and medical usage
KR101191070B1 (en) * 2004-02-17 2012-10-15 산토리 홀딩스 가부시키가이샤 Lipase activity inhibitor containing high-molecular weight polyphenol fraction, tea extract and process for producing the same
CN1243095C (en) 2004-03-11 2006-02-22 陕西省动物研究所 Extracting process of actinidia proteinase
RU2328951C1 (en) 2004-04-08 2008-07-20 Джапан Тобакко Инк. Tobacco cake subdividing apparatus for use in cut tobacco expanding system
US20060024392A1 (en) 2004-04-20 2006-02-02 The University Of Maryland Compositions and methods for enhancing the effectiveness of a chemotherapeutic agent
US20090226555A1 (en) 2004-08-10 2009-09-10 Helixir Co., Ltd. Extract of actinidia arguta for preventing and treating baldness disorders and seborrheic skin disorders

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02202808A (en) * 1989-01-31 1990-08-10 Ichimaru Pharcos Co Ltd Extract solution of kiwi fruit or concentrated extract of the same solution
JPH06256207A (en) * 1991-09-06 1994-09-13 Yoko Fukuya Anti-mutagen substance, antiviral substance and cell growth promoting substance
JP2002293780A (en) * 2001-03-30 2002-10-09 Sakamoto Koryo Kk Kiwi catechin and method for producing the same
WO2004017982A1 (en) * 2002-08-23 2004-03-04 Pangenomics Co., Ltd Composition comprising the extract of actinidia arguta and related species for the prevention and treatment of allergic disease and non-allergic inflammatory disease
KR20040097716A (en) * 2003-05-13 2004-11-18 주식회사 팬제노믹스 Health food comprising the extract of Actinidia arguta for preventing and improving baldness disorders and seborrheic skin disorders

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
DATABASE WPI Week 199441, Derwent World Patents Index; AN 1994-329945, XP002514190 *
DATABASE WPI Week 200316, Derwent World Patents Index; AN 2003-160143, XP002514189 *
DATABASE WPI Week 200525, Derwent World Patents Index; AN 2005-238966, XP002514191 *
TAKANO FUMIHIDE ET AL: "Isolation of (+)-catechin and (-)-epicatechin from Actinidia arguta as bone marrow cell proliferation promoting compounds.", PLANTA MEDICA, vol. 69, no. 4, April 2003 (2003-04-01), pages 321 - 326, XP002514188, ISSN: 0032-0943 *

Also Published As

Publication number Publication date
EP2018176A2 (en) 2009-01-28
JP2010503609A (en) 2010-02-04
US20070259059A1 (en) 2007-11-08
CN101522204A (en) 2009-09-02
WO2008023266A2 (en) 2008-02-28
JP5290158B2 (en) 2013-09-18
CN101522204B (en) 2012-09-05
US7862840B2 (en) 2011-01-04
AT503521A1 (en) 2007-11-15

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