WO2008045928A1 - Orthodontic implants - Google Patents

Orthodontic implants Download PDF

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Publication number
WO2008045928A1
WO2008045928A1 PCT/US2007/080927 US2007080927W WO2008045928A1 WO 2008045928 A1 WO2008045928 A1 WO 2008045928A1 US 2007080927 W US2007080927 W US 2007080927W WO 2008045928 A1 WO2008045928 A1 WO 2008045928A1
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WO
WIPO (PCT)
Prior art keywords
implant
neck
orthodontic
section
orthodontic implant
Prior art date
Application number
PCT/US2007/080927
Other languages
French (fr)
Inventor
Kevin Corcoran
Jefferson Sabilla
Original Assignee
Ormco Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ormco Corporation filed Critical Ormco Corporation
Priority to PCT/US2007/080927 priority Critical patent/WO2008045928A1/en
Publication of WO2008045928A1 publication Critical patent/WO2008045928A1/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61CDENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
    • A61C7/00Orthodontics, i.e. obtaining or maintaining the desired position of teeth, e.g. by straightening, evening, regulating, separating, or by correcting malocclusions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61CDENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
    • A61C8/00Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools
    • A61C8/0093Features of implants not otherwise provided for
    • A61C8/0096Implants for use in orthodontic treatment

Definitions

  • This invention generally relates to orthodontic devices, and more particularly, to orthodontic implants, which are sometimes referred to as miniscrews, and may also be used in dental applications as appropriate.
  • Dental implants are used in the dental profession in general, and more particularly in the branches or specialties of orthodontics, oral surgery, periodontics, and restorative dentistry. More specifically, an orthodontist may use an orthodontic implant to provide a firm anchorage from which to attach wires, springs, and like peripheral devices for use in aligning or straightening misaligned or irregular teeth. The use of such an implant allows for a skeletal anchorage which is more predictable and stable than using headgear or elastics which require patient compliance.
  • a skeletal anchorage also eliminates the need for using other teeth as an anchor This in turn, eliminates the unwanted movement of these anchor teeth, for when one tooth is used as an anchor to move another, the anchor tooth will also move, even if only to a lesser degree, while the irregular or misaligned tooth moves.
  • orthodontic implants can be advantageously used in orthodontic treatment to control tooth movement
  • many of the orthodontic implants in the market have a round screw head a bracket-shaped head, or a hex-shaped head
  • One possible drawback to these designs is that typically attachments are secured to these miniscrews by placing a round eyelet (i e , like that typically found on a coil spring) over the head of the screw and hoping the undercut or neck (beneath the screw head) is sufficient to retain the eyelet in place
  • attachments are ligated onto the head of the screw or implant, which can be a very cumbersome technique
  • the present invention relates to an orthodontic implant or miniscrew with a non-circular shaped head
  • the implants are contemplated for use in both orthodontic or dental applications, both of which are referred to by the reference to orthodontic implants
  • the head has an elliptical shape
  • the head has a triangular or delta shape
  • Utilizing a non-circular (elliptical or delta) shaped head provides the advantage that when an eyeiet is utilized which has the same shape as the non-circular head, then once the eyelet has been placed over the head portion of the implant and the eyelet and implant are rotated relative to one another, unless the two ellipses (head and eyelet) become perfectly aligned, the eyelet will not inadvertently become disengaged from the implant head
  • the mating eyelet to be used with such an implant would also have a triangular or delta shape
  • an additional benefit to utilizing an elliptical shaped head on an orthodontic implant is achieved if the elliptical shape extends to the neck portion of the implant In other words, although the neck would have reduced dimensions relative to the head itself, the neck would have the elliptical shape proportionately like the head itself. Utilizing such a design provides reinforcement to the neck and may prevent possible fracturing of the orthodontic implant, particularly during the implantation step.
  • the neck may have a transverse hole through it which allows for wires, ligatures or other devices to be inserted through and tied to the implant, in the situation where a through hole is utilized in the neck of the implant, having an elliptical shape to the neck will add additiona! reinforcement vis-a-vis a typical circular shaped neck.
  • the orthodontic implants of the present invention may utilize a typical circular cross-section for the neck in the form of a cylindrical section wherein the diameter does not vary along the length of the neck.
  • the neck region of the implant below the head may have an "apple core” configuration to further enhance retention of the eyelet.
  • This "apple core” configuration can be used on either the elliptical or triangular shaped head embodiments of the invention.
  • the "apple core” neck configuration is advantageous in that it allows greater freedom of movement of an eyelet around the neck of the implant in both a rotational sense and in a vertical/tipping sense.
  • Fig 1 is a perspective view of an embodiment of an orthodontic implant in the oral environment
  • Fig 2 is a perspective view of the orthodontic implant shown in Fig 1 .
  • Fig 2A is a top view of the orthodontic implant shown in Fig 2,
  • Fig 2B is a side view of the orthodontic implant show in Fig 2,
  • Fig 3 is a side view of a portion of an alternative embodiment of the neck portion of an orthodontic implant
  • Fig 4 is a top view of the neck and head portion of the orthodontic implant shown in Fig 3,
  • Fig 5 is a perspective view of an aiternative embodiment of an orthodontic implant.
  • Fig 6 is an end view of the orthodontic implant shown in Fig 6
  • Fsgs 1 and 2 show an embodiment of an orthodontic implant 10 of the present invention
  • Implant 10 includes a threaded shaft portion 12, an ellsptically shaped head 14, a neck portion 16, a smooth cylindrical shaft portion 18, and an antt- gingival growth barrier 20 (also referred to as a transmucosai collar)
  • Orthodontic implant 10 which is of a one-piece construction and is made of any suitable material, such as titanium or titanium alloy, is advantageously used with an auxiliary orthodontic device having an eyelet 22 at an end thereof, such as is shown in Fig 1.
  • the eyelet 22 is shaped to fit over the elliptical head 14 of implant 10
  • various suitable eyelets are found in co-pending PCT International application No , filed on October 10, 2007 entitled "Orthodontic Eyelet With C ⁇ mpabJe Portions and Related Methods," whsch is expressly incorporated by reference herein in its entirety
  • auxiliary devices having swivel eyelets may advantageously be used with the orthodontic implants of the present invention
  • Such devices are disclosed in co-pending PCT Internationa! application No , filed October 10, 2007, entitled Orthodontic
  • Figs 2A and 2b show top and side views, respectively, of the orthodontic implant 10 shown in Fig 2
  • the neck portion 16 of the implant 10 is cylindrical and has a circular cross-section with a through hole 24
  • the through hole 24 permits inserting a wire or spring end into and through the neck of the implant 10 and tying it in place
  • the neck 16 may have
  • Figs 3 and 4 show an alternative configuration for the neck portion 16 of implant 10 wherein the neck has an "apple core” configuration More particularly, in this embodiment, the diameter or circular cross-section of the neck 16 varies in the longitudinal direction from a narrow mid-point 17 to two flared end points 19a and 19b This "apple core” configuration of neck 16 may further enhance the retention of an eyelet on the orthodontic implant because there is a more pronounced undercut beneath the head 14 This "apple core” neck embodiment may also include a through- hole 24 for wire or spring attachment [0023]
  • Figs 5 and 6 depict an alternative embodiment of the invention wherein the non-circular head portion of the implant 10 has a triangular (or delta) shaped head 28 As shown in Fig 5, the neck portion 30 of the triangular shaped head embodiment may be circular in cross-section It is also contemplated that the "apple core” neck configuration shown in Figs 3 and 4 may also be utilized Furthermore, in this embodiment, the region below the neck 30 has a triangular shaped cross-
  • the orthodontic implants of this invention may be coated with an antimicrobial so as to inhibit or prevent infections subsequent to implantation
  • Suitable antimicrobial coatings for the implant may include silver alloys and materials containing zinc ions or silver ions
  • a starter hole is drilled in the patient's bony structure that is to receive the orthodontic implant utilizing the drill disclosed in this co-pending application
  • a dual option driver of the type disclosed in co-pending PCT International application No can be used to drive the orthodontic impiant into its final position
  • an orthodontic clinician may apply a topical anesthetic such as Profound or other suitable topical anesthetics known in the art, to the patient's gum and thereafter use a needle-less injector such as MadaJet, available from Mada, International (New Jersey) or Sy ⁇ Jet, available from Mizzt (New Jersey) to inject a suitable anesthetic Needle-less injectors are known in the field of general dentistry to inject an appropriate anesthetic into the patient Needle-less injection may advantageously be used in connection with the implantation of orthodontic implants of the present

Abstract

The present invention embodies orthodontic (including dental) implants (10) having a threaded shaft section (12), a neck (16), and a head (14, 28) of non-circular cross-section such as elliptical or delta-shaped. The neck (16) of implant (10) may be circular in cross-section (30), elliptical, or it may have an 'apple core' configuration (16,17, 19a and b). Neck (16) of implant (10) may also have a through-hole 24, and implant (10) may further include an anti-gingival growth barrier (20) such as a transmucosal collar. Moreover, anti-microbial coatings or materials may be included as part of implant (10).

Description

ORTHODONTIC iMPLANTS PRIORITY CLAIM
[0001] This application claims the benefit of U S Provisional Patent Application
Serial No 60/850,624, filed October 10, 2006 and entitled "Orthodontic Devices, Implants and Related Apparatus," the disclosure of which is expressly incorporated by reference herein in its entirety. TECHNICAL FIELD
[0002] This invention generally relates to orthodontic devices, and more particularly, to orthodontic implants, which are sometimes referred to as miniscrews, and may also be used in dental applications as appropriate. BACKGROUND
[0003] Dental implants are used in the dental profession in general, and more particularly in the branches or specialties of orthodontics, oral surgery, periodontics, and restorative dentistry. More specifically, an orthodontist may use an orthodontic implant to provide a firm anchorage from which to attach wires, springs, and like peripheral devices for use in aligning or straightening misaligned or irregular teeth. The use of such an implant allows for a skeletal anchorage which is more predictable and stable than using headgear or elastics which require patient compliance. A skeletal anchorage also eliminates the need for using other teeth as an anchor This in turn, eliminates the unwanted movement of these anchor teeth, for when one tooth is used as an anchor to move another, the anchor tooth will also move, even if only to a lesser degree, while the irregular or misaligned tooth moves. In short, orthodontic implants can be advantageously used in orthodontic treatment to control tooth movement [0004] Currently many of the orthodontic implants in the market have a round screw head a bracket-shaped head, or a hex-shaped head One possible drawback to these designs is that typically attachments are secured to these miniscrews by placing a round eyelet (i e , like that typically found on a coil spring) over the head of the screw and hoping the undercut or neck (beneath the screw head) is sufficient to retain the eyelet in place Alternatively, attachments are ligated onto the head of the screw or implant, which can be a very cumbersome technique
[0005] What is needed is an improved orthodontic implant having a structure that more securely receives an eyelet and that is less susceptible to fracture in the neck region SUMMARY
£0006] The present invention relates to an orthodontic implant or miniscrew with a non-circular shaped head The implants are contemplated for use in both orthodontic or dental applications, both of which are referred to by the reference to orthodontic implants In one embodiment, the head has an elliptical shape In an alternative embodiment, the head has a triangular or delta shape Utilizing a non-circular (elliptical or delta) shaped head provides the advantage that when an eyeiet is utilized which has the same shape as the non-circular head, then once the eyelet has been placed over the head portion of the implant and the eyelet and implant are rotated relative to one another, unless the two ellipses (head and eyelet) become perfectly aligned, the eyelet will not inadvertently become disengaged from the implant head With respect to the alternative embodiment wherein the orthodontic implant has a triangular or delta shaped head, the mating eyelet to be used with such an implant would also have a triangular or delta shape
[0007] An additional benefit to utilizing an elliptical shaped head on an orthodontic implant is achieved if the elliptical shape extends to the neck portion of the implant In other words, although the neck would have reduced dimensions relative to the head itself, the neck would have the elliptical shape proportionately like the head itself. Utilizing such a design provides reinforcement to the neck and may prevent possible fracturing of the orthodontic implant, particularly during the implantation step. [0008] It is further contemplated that the neck may have a transverse hole through it which allows for wires, ligatures or other devices to be inserted through and tied to the implant, in the situation where a through hole is utilized in the neck of the implant, having an elliptical shape to the neck will add additiona! reinforcement vis-a-vis a typical circular shaped neck.
[0009] As an alternative to the elliptical shaped neck described above, the orthodontic implants of the present invention may utilize a typical circular cross-section for the neck in the form of a cylindrical section wherein the diameter does not vary along the length of the neck. As a further aiternative, the neck region of the implant below the head may have an "apple core" configuration to further enhance retention of the eyelet. This "apple core" configuration can be used on either the elliptical or triangular shaped head embodiments of the invention. The "apple core" neck configuration is advantageous in that it allows greater freedom of movement of an eyelet around the neck of the implant in both a rotational sense and in a vertical/tipping sense. This is advantageous because not all implants are implanted at a right angle to the skeletal structure and freedom of movement of an eyelet in multiple directions about the implant neck may be important to the functioning of the device. [0010] The above and other objects and advantages of the present invention shal! be made apparent from the accompanying drawings and the detailed description thereof.
BRIEF DESCRIPTION QF THE DRAWINGS
[0011] Various additional features and aspects will become readily apparent to those of ordinary skill in the art from the following description of illustrative embodiments of the invention and from the drawings in which: {0012] Fig 1 is a perspective view of an embodiment of an orthodontic implant in the oral environment,
[0013] Fig 2 is a perspective view of the orthodontic implant shown in Fig 1 ,
[0014] Fig 2A is a top view of the orthodontic implant shown in Fig 2,
[0015] Fig 2B is a side view of the orthodontic implant show in Fig 2,
[0016] Fig 3 is a side view of a portion of an alternative embodiment of the neck portion of an orthodontic implant,
[0017] Fig 4 is a top view of the neck and head portion of the orthodontic implant shown in Fig 3,
[0018] Fig 5 is a perspective view of an aiternative embodiment of an orthodontic implant, and
[0019] Fig 6 is an end view of the orthodontic implant shown in Fig 6
DETAILED DESCRIPTION
[0020] Fsgs 1 and 2 show an embodiment of an orthodontic implant 10 of the present invention Implant 10 includes a threaded shaft portion 12, an ellsptically shaped head 14, a neck portion 16, a smooth cylindrical shaft portion 18, and an antt- gingival growth barrier 20 (also referred to as a transmucosai collar) Orthodontic implant 10, which is of a one-piece construction and is made of any suitable material, such as titanium or titanium alloy, is advantageously used with an auxiliary orthodontic device having an eyelet 22 at an end thereof, such as is shown in Fig 1. As shown, the eyelet 22 is shaped to fit over the elliptical head 14 of implant 10 Details of various suitable eyelets are found in co-pending PCT International application No , filed on October 10, 2007 entitled "Orthodontic Eyelet With CπmpabJe Portions and Related Methods," whsch is expressly incorporated by reference herein in its entirety Moreover, auxiliary devices having swivel eyelets may advantageously be used with the orthodontic implants of the present invention Such devices are disclosed in co-pending PCT Internationa! application No , filed October 10, 2007, entitled Orthodontic
Auxiliary Device Having a Swive! for Adapting to Impiants," which is expressly incorporated by reference herein in its entirety The use of an elliptical shaped head 14 in the orthodontic implant 10 of the present invention is advantageous because the eyelet 22 which has a mating shape is less readily displaced off of the neck and head of the orthodontic implant during treatment The reason for this is that only when the implant head 14 and eyelet 22 opening 23 are in 100% alignment is it possible for the eyelet to become disengaged This has the advantage that no additional ligation is required to maintain the eyelet in place on the orthodontic implant [0021] Figs 2A and 2b show top and side views, respectively, of the orthodontic implant 10 shown in Fig 2 As can be seen in Figs 2A and 2B, the neck portion 16 of the implant 10 is cylindrical and has a circular cross-section with a through hole 24 The through hole 24 permits inserting a wire or spring end into and through the neck of the implant 10 and tying it in place As an alternative, it will be appreciated that the neck 16 may have an elliptical cross-section (not shown) that corresponds to the elliptical shaped head 14, but ΪS of reduced dimensions relative thereto Such a configuration for the neck 16 strengthens the neck and may prevent cracking or implant failures, especially during the implantation step
[0022] Figs 3 and 4 show an alternative configuration for the neck portion 16 of implant 10 wherein the neck has an "apple core" configuration More particularly, in this embodiment, the diameter or circular cross-section of the neck 16 varies in the longitudinal direction from a narrow mid-point 17 to two flared end points 19a and 19b This "apple core" configuration of neck 16 may further enhance the retention of an eyelet on the orthodontic implant because there is a more pronounced undercut beneath the head 14 This "apple core" neck embodiment may also include a through- hole 24 for wire or spring attachment [0023] Figs 5 and 6 depict an alternative embodiment of the invention wherein the non-circular head portion of the implant 10 has a triangular (or delta) shaped head 28 As shown in Fig 5, the neck portion 30 of the triangular shaped head embodiment may be circular in cross-section It is also contemplated that the "apple core" neck configuration shown in Figs 3 and 4 may also be utilized Furthermore, in this embodiment, the region below the neck 30 has a triangular shaped cross-section 32 which facilitates the use of an orthodontic driver device for screwing the implant into place An example of a dual option driver is disclosed in co-pending PCT International application No filed on October 10, 2007 entitled "Dual Option Driver "
The devices disclosed in that co-pending application may be utilized with the orthodontic implants of the present invention and the entirety of that co-pending application is incorporated by reference herein
[0024] It is further contemplated that the orthodontic implants of this invention may be coated with an antimicrobial so as to inhibit or prevent infections subsequent to implantation Suitable antimicrobial coatings for the implant may include silver alloys and materials containing zinc ions or silver ions
[0025] In connection with the implantation of the orthodontic implants of the present invention, it will be appreciated that a drill for orthodontic implants of the type disclosed in co-pending PCT International application No filed on October
10, 2007, entitled "Drill for Orthodontic Implants," the details of which are expressly incorporated herein by reference may be used With such a device, a starter hole is drilled in the patient's bony structure that is to receive the orthodontic implant utilizing the drill disclosed in this co-pending application Thereafter, a dual option driver of the type disclosed in co-pending PCT International application No , referenced above, can be used to drive the orthodontic impiant into its final position Prior to use of the drill and driver, an orthodontic clinician may apply a topical anesthetic such as Profound or other suitable topical anesthetics known in the art, to the patient's gum and thereafter use a needle-less injector such as MadaJet, available from Mada, International (New Jersey) or SyπJet, available from Mizzt (New Jersey) to inject a suitable anesthetic Needle-less injectors are known in the field of general dentistry to inject an appropriate anesthetic into the patient Needle-less injection may advantageously be used in connection with the implantation of orthodontic implants of the present invention
[0026] While the present invention has been illustrated by a description of one or more embodiments and while these embodiments have been described in detail, it is not the intention of the applicant to restrict or in any way limit the scope of the claims to such detail Additional advantages and modifications will readily appear to those skilled in the art The invention in its broader aspects is, therefore, not limited to the specific details, representative systems, apparatus and method, and illustrative examples shown and described Accordingly, departures may be made from such details without departing from the spirit or scope of the applicant's inventive concept [0027] What is claimed is

Claims

1 An orthodontic smplant having a threaded section, a neck and a head portion, wherein said head portion has a non-circular cross-section that is elliptical in cross- section
2 The orthodontic implant of claim 1 wherein said neck has a circular cross- section
3 The orthodontic implant of claim 1 wherein said neck has a varying diameter along its length so as to resemble an apple core
4 The orthodontic implant of claim 1 wherein sasd neck has a through hole transverse to the axis of the implant
5 The orthodontic implant of claim 1 wherein said neck has an elliptical cross- section that corresponds to, but is of reduced dimensions, relative to the elliptical head
6 The orthodontic implant of claim 1 further comprising an anti-gingival growth barrier between the threaded section and the neck
7 The orthodontic implant of claim 6 wherein said anti-gingival growth barrier is a transmucosal collar
8 The orthodontic implant of claim 1 further comprising a dπvable portion between the threaded portion and the neck portion, wherein said dπvable portion has a non- circular cross-section corresponding to that of said head portion 9 The orthodontic implant of claim 1 , wherein said implant includes an antimicrobial
10 An orthodontic implant having a threaded section, a neck and a head portion, wherein said head portion has a non-circular cross-section that is delta-shaped in cross-section
1 1 The orthodontic implant of claim 10 wherein said neck has a circular cross- section
12 The orthodontic implant of claim 10 wherein said neck has a varying diameter along its length so as to resemble an apple core
13 The orthodontic implant of claim 10 wherein said neck has a through hole transverse to the axis of the implant
14 The orthodontic implant of claim 10 wherein said neck has an delta-shaped cross-section that corresponds to, but is of reduced dimensions, relative to the delta- shaped head
15 The orthodontic impiant of claim 10 further comprising an anti-gingival growth barrier between the threaded section and the neck
16 The orthodontic impiant of claim 15 wherein said anti-gingival growth barrier is a transmucosal collar 17 The orthodontic implant of claim 10 further comprising a dπvable portion between the threaded portion and the neck portion, wherein said dπvable portion has a non- αrcuiar cross-section corresponding to that of said head portion
18 The orthodontic impiant of claim 15 wherein said implant includes an antimicrobial
19 A method of implanting an orthodontic implant, comprising applying a topical anesthetic to a patient's gingiva, utilizing a needless injector to inject an anesthetic into the patient's gingiva, and implanting an orthodontic implant in the patient at a desired location
20 The method of claim 19 further comprising drilling a starter hole in the patient's skeletal structure at a desired location of implantation
PCT/US2007/080927 2006-10-10 2007-10-10 Orthodontic implants WO2008045928A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PCT/US2007/080927 WO2008045928A1 (en) 2006-10-10 2007-10-10 Orthodontic implants

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US85062406P 2006-10-10 2006-10-10
US60/850,624 2006-10-10
PCT/US2007/080927 WO2008045928A1 (en) 2006-10-10 2007-10-10 Orthodontic implants

Publications (1)

Publication Number Publication Date
WO2008045928A1 true WO2008045928A1 (en) 2008-04-17

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PCT/US2007/080927 WO2008045928A1 (en) 2006-10-10 2007-10-10 Orthodontic implants

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015158825A1 (en) * 2014-04-17 2015-10-22 Kamber Michael Means and methods for preventing or treating dental implant associated inflammation
RU2647156C1 (en) * 2016-06-15 2018-03-14 Елена Анатольевна Логинова Orthodontic abutment

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6214049B1 (en) * 1999-01-14 2001-04-10 Comfort Biomedical, Inc. Method and apparatus for augmentating osteointegration of prosthetic implant devices
EP1108398A2 (en) * 1999-12-17 2001-06-20 Nobel Biocare AB (publ) Bone implant
WO2002003880A1 (en) * 2000-07-12 2002-01-17 Park Young Chel Implant for teeth orthodontics
US20030224315A1 (en) * 2002-06-04 2003-12-04 Cheng-Yi Lin Screw device for orthodontic treatment

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6214049B1 (en) * 1999-01-14 2001-04-10 Comfort Biomedical, Inc. Method and apparatus for augmentating osteointegration of prosthetic implant devices
EP1108398A2 (en) * 1999-12-17 2001-06-20 Nobel Biocare AB (publ) Bone implant
WO2002003880A1 (en) * 2000-07-12 2002-01-17 Park Young Chel Implant for teeth orthodontics
US20030224315A1 (en) * 2002-06-04 2003-12-04 Cheng-Yi Lin Screw device for orthodontic treatment

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015158825A1 (en) * 2014-04-17 2015-10-22 Kamber Michael Means and methods for preventing or treating dental implant associated inflammation
CN106535951A (en) * 2014-04-17 2017-03-22 阿克蒂姆普朗特股份公司 Means and methods for preventing or treating dental implant associated inflammation
RU2647156C1 (en) * 2016-06-15 2018-03-14 Елена Анатольевна Логинова Orthodontic abutment

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