WO2008076574A3 - Temperature compensation for enzyme electrodes - Google Patents

Temperature compensation for enzyme electrodes Download PDF

Info

Publication number
WO2008076574A3
WO2008076574A3 PCT/US2007/084993 US2007084993W WO2008076574A3 WO 2008076574 A3 WO2008076574 A3 WO 2008076574A3 US 2007084993 W US2007084993 W US 2007084993W WO 2008076574 A3 WO2008076574 A3 WO 2008076574A3
Authority
WO
WIPO (PCT)
Prior art keywords
temperature compensation
enzyme
enzyme electrodes
deviation
measurement
Prior art date
Application number
PCT/US2007/084993
Other languages
French (fr)
Other versions
WO2008076574A2 (en
Inventor
Todd Fjield
Michael J Higgins
Kenneth Curry
Patrick Carlin
Original Assignee
Edwards Lifesciences Corp
Todd Fjield
Michael J Higgins
Kenneth Curry
Patrick Carlin
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Edwards Lifesciences Corp, Todd Fjield, Michael J Higgins, Kenneth Curry, Patrick Carlin filed Critical Edwards Lifesciences Corp
Priority to CA002667243A priority Critical patent/CA2667243A1/en
Priority to EP07871509A priority patent/EP2088927A2/en
Publication of WO2008076574A2 publication Critical patent/WO2008076574A2/en
Publication of WO2008076574A3 publication Critical patent/WO2008076574A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001—Enzyme electrodes
    • C12Q1/005—Enzyme electrodes involving specific analytes or enzymes
    • C12Q1/006—Enzyme electrodes involving specific analytes or enzymes for glucose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1486—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using enzyme electrodes, e.g. with immobilised oxidase
    • A61B5/14865—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using enzyme electrodes, e.g. with immobilised oxidase invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1495—Calibrating or testing of in-vivo probes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2560/00—Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
    • A61B2560/02—Operational features
    • A61B2560/0242—Operational features adapted to measure environmental factors, e.g. temperature, pollution
    • A61B2560/0247—Operational features adapted to measure environmental factors, e.g. temperature, pollution for compensation or correction of the measured physiological value
    • A61B2560/0252—Operational features adapted to measure environmental factors, e.g. temperature, pollution for compensation or correction of the measured physiological value using ambient temperature

Abstract

A temperature compensation method for an enzyme electrode by measuring an operating temperature of the enzyme electrode, measuring the current generated by the enzyme electrode, determining a deviation in measurement between the current generated and a reference current at the operating temperature, determining an enzyme concentration corresponding to the measured current, and calibrating the enzyme concentration to compensate for the deviation in measurement.
PCT/US2007/084993 2006-11-16 2007-11-16 Temperature compensation for enzyme electrodes WO2008076574A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CA002667243A CA2667243A1 (en) 2006-11-16 2007-11-16 Temperature compensation for enzyme electrodes
EP07871509A EP2088927A2 (en) 2006-11-16 2007-11-16 Temperature compensation for enzyme electrodes

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US85958606P 2006-11-16 2006-11-16
US60/859,586 2006-11-16

Publications (2)

Publication Number Publication Date
WO2008076574A2 WO2008076574A2 (en) 2008-06-26
WO2008076574A3 true WO2008076574A3 (en) 2009-02-05

Family

ID=39536945

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/084993 WO2008076574A2 (en) 2006-11-16 2007-11-16 Temperature compensation for enzyme electrodes

Country Status (4)

Country Link
EP (1) EP2088927A2 (en)
CN (1) CN101541239A (en)
CA (1) CA2667243A1 (en)
WO (1) WO2008076574A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2766339A1 (en) * 2009-06-30 2011-01-06 Arkray, Inc. Analysis device and analysis method
TWI458979B (en) * 2011-03-18 2014-11-01 Eps Bio Technology Corp Biosensor having a function of environment temperature compensating and method thereof
CN109790562B (en) * 2016-09-07 2023-08-15 豪夫迈·罗氏有限公司 Method for testing an enzyme-based electrochemical sensor

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4431004A (en) * 1981-10-27 1984-02-14 Bessman Samuel P Implantable glucose sensor
US4703756A (en) * 1986-05-06 1987-11-03 The Regents Of The University Of California Complete glucose monitoring system with an implantable, telemetered sensor module
US20050177035A1 (en) * 2003-12-18 2005-08-11 Elliot Botvinick Implantable biosensor and methods of use thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4431004A (en) * 1981-10-27 1984-02-14 Bessman Samuel P Implantable glucose sensor
US4703756A (en) * 1986-05-06 1987-11-03 The Regents Of The University Of California Complete glucose monitoring system with an implantable, telemetered sensor module
US20050177035A1 (en) * 2003-12-18 2005-08-11 Elliot Botvinick Implantable biosensor and methods of use thereof

Also Published As

Publication number Publication date
EP2088927A2 (en) 2009-08-19
CA2667243A1 (en) 2008-06-26
CN101541239A (en) 2009-09-23
WO2008076574A2 (en) 2008-06-26

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