WO2009091456A3 - Mass spectrometer with looped ion path - Google Patents
Mass spectrometer with looped ion path Download PDFInfo
- Publication number
- WO2009091456A3 WO2009091456A3 PCT/US2008/085734 US2008085734W WO2009091456A3 WO 2009091456 A3 WO2009091456 A3 WO 2009091456A3 US 2008085734 W US2008085734 W US 2008085734W WO 2009091456 A3 WO2009091456 A3 WO 2009091456A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- ion path
- ion
- mass spectrometer
- looped
- isolation
- Prior art date
Links
- 150000002500 ions Chemical class 0.000 abstract 7
- 238000013467 fragmentation Methods 0.000 abstract 2
- 238000006062 fragmentation reaction Methods 0.000 abstract 2
- 238000002955 isolation Methods 0.000 abstract 2
- 238000001819 mass spectrum Methods 0.000 abstract 1
Classifications
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/004—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn
- H01J49/0081—Tandem in time, i.e. using a single spectrometer
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/02—Details
- H01J49/06—Electron- or ion-optical arrangements
- H01J49/062—Ion guides
Abstract
A mass spectrometer includes at least one ion selector, at least one collision cell, and an ion path switching device arranged to define a looped ion path around which ions derived from a sample may be sent multiple times (without reversal of ion travel) in order to effect a desired number of isolation/fragmentation cycles for MSn analysis. When the desired number of isolation/fragmentation cycles have been completed, the ion path switching device directs the ions to a detector or a separate mass analyzer for acquisition of a mass spectrum.
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA2711534A CA2711534A1 (en) | 2008-01-11 | 2008-12-05 | Mass spectrometer with looped ion path |
EP08870861A EP2242560A2 (en) | 2008-01-11 | 2008-12-05 | Mass spectrometer with looped ion path |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12/013,352 US7932487B2 (en) | 2008-01-11 | 2008-01-11 | Mass spectrometer with looped ion path |
US12/013,352 | 2008-01-11 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2009091456A2 WO2009091456A2 (en) | 2009-07-23 |
WO2009091456A3 true WO2009091456A3 (en) | 2011-07-28 |
Family
ID=40849834
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2008/085734 WO2009091456A2 (en) | 2008-01-11 | 2008-12-05 | Mass spectrometer with looped ion path |
Country Status (4)
Country | Link |
---|---|
US (1) | US7932487B2 (en) |
EP (1) | EP2242560A2 (en) |
CA (1) | CA2711534A1 (en) |
WO (1) | WO2009091456A2 (en) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8680479B2 (en) * | 2007-05-09 | 2014-03-25 | Shimadzu Corporation | Charged particle analyzer |
WO2009066354A1 (en) * | 2007-11-21 | 2009-05-28 | Shimadzu Corporation | Mass spectrometry device |
WO2010032276A1 (en) * | 2008-09-16 | 2010-03-25 | 株式会社島津製作所 | Time-of-flight mass spectrometer |
US20110248161A1 (en) * | 2008-10-02 | 2011-10-13 | Shimadzu Corporation | Multi-Turn Time-of-Flight Mass Spectrometer |
WO2010041296A1 (en) * | 2008-10-09 | 2010-04-15 | 株式会社島津製作所 | Mass spectrometer |
EP2380184A1 (en) * | 2009-01-09 | 2011-10-26 | Mds Analytical Technologies | Mass spectrometer |
GB0900973D0 (en) * | 2009-01-21 | 2009-03-04 | Micromass Ltd | Method and apparatus for performing MS^N |
US8203118B2 (en) * | 2009-12-11 | 2012-06-19 | Honeywell International, Inc. | Ion-trap mass spectrometer driven by a monolithic photodiode array |
EP2513946B1 (en) * | 2009-12-18 | 2018-02-14 | DH Technologies Development Pte. Ltd. | Method of processing ions |
GB2476964A (en) * | 2010-01-15 | 2011-07-20 | Anatoly Verenchikov | Electrostatic trap mass spectrometer |
CN103109346B (en) * | 2010-11-08 | 2016-09-28 | Dh科技发展私人贸易有限公司 | For the system and method by mass spectral analysis rapid screening sample |
GB201117158D0 (en) | 2011-10-05 | 2011-11-16 | Micromass Ltd | Ion guide |
GB201118279D0 (en) | 2011-10-21 | 2011-12-07 | Shimadzu Corp | Mass analyser, mass spectrometer and associated methods |
GB201120307D0 (en) | 2011-11-24 | 2012-01-04 | Thermo Fisher Scient Bremen | High duty cycle mass spectrometer |
US8785847B2 (en) * | 2012-02-15 | 2014-07-22 | Thermo Finnigan Llc | Mass spectrometer having an ion guide with an axial field |
DE112015001187B4 (en) | 2014-03-10 | 2022-12-22 | Micromass Uk Limited | Process for separating ions according to a physicochemical property |
KR20160069077A (en) * | 2014-12-05 | 2016-06-16 | 현대오트론 주식회사 | Battery monitoring method and apparatus performing the same |
CN107845561A (en) * | 2016-09-18 | 2018-03-27 | 江苏可力色质医疗器械有限公司 | A kind of MS/MS collision reaction tank and analysis method for reducing cross jamming |
US10319572B2 (en) | 2017-09-28 | 2019-06-11 | Northrop Grumman Systems Corporation | Space ion analyzer with mass spectrometer on a chip (MSOC) using floating MSOC voltages |
JP6808669B2 (en) * | 2018-03-14 | 2021-01-06 | 日本電子株式会社 | Mass spectrometer |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2007066114A2 (en) * | 2005-12-07 | 2007-06-14 | Micromass Uk Limited | Mass spectrometer |
WO2007104992A2 (en) * | 2006-03-14 | 2007-09-20 | Micromass Uk Limited | Mass spectrometer |
Family Cites Families (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH11135060A (en) * | 1997-10-31 | 1999-05-21 | Jeol Ltd | Flight time type mass spectrometer |
US6504148B1 (en) * | 1999-05-27 | 2003-01-07 | Mds Inc. | Quadrupole mass spectrometer with ION traps to enhance sensitivity |
DE19960020A1 (en) | 1999-12-13 | 2001-06-21 | Ruediger Marmulla | Device for optical detection and referencing between data set, surgical site and 3D marker system for instrument and bone segment navigation |
US6720554B2 (en) | 2000-07-21 | 2004-04-13 | Mds Inc. | Triple quadrupole mass spectrometer with capability to perform multiple mass analysis steps |
US6570153B1 (en) | 2000-10-18 | 2003-05-27 | Agilent Technologies, Inc. | Tandem mass spectrometry using a single quadrupole mass analyzer |
WO2002048699A2 (en) | 2000-12-14 | 2002-06-20 | Mds Inc. Doing Business As Mds Sciex | Apparatus and method for msnth in a tandem mass spectrometer system |
US7049580B2 (en) * | 2002-04-05 | 2006-05-23 | Mds Inc. | Fragmentation of ions by resonant excitation in a high order multipole field, low pressure ion trap |
US6867414B2 (en) * | 2002-09-24 | 2005-03-15 | Ciphergen Biosystems, Inc. | Electric sector time-of-flight mass spectrometer with adjustable ion optical elements |
JP4229732B2 (en) * | 2003-03-19 | 2009-02-25 | 日本電子株式会社 | Time-of-flight mass spectrometer |
JP4182843B2 (en) * | 2003-09-02 | 2008-11-19 | 株式会社島津製作所 | Time-of-flight mass spectrometer |
JP4208674B2 (en) * | 2003-09-03 | 2009-01-14 | 日本電子株式会社 | Multi-turn time-of-flight mass spectrometry |
JP4182844B2 (en) * | 2003-09-03 | 2008-11-19 | 株式会社島津製作所 | Mass spectrometer |
JP4182853B2 (en) * | 2003-10-08 | 2008-11-19 | 株式会社島津製作所 | Mass spectrometry method and mass spectrometer |
JP4001100B2 (en) * | 2003-11-14 | 2007-10-31 | 株式会社島津製作所 | Mass spectrometer |
JP4033133B2 (en) * | 2004-01-13 | 2008-01-16 | 株式会社島津製作所 | Mass spectrometer |
JP2005322429A (en) * | 2004-05-06 | 2005-11-17 | Shimadzu Corp | Mass spectrometer |
JP4980583B2 (en) * | 2004-05-21 | 2012-07-18 | 日本電子株式会社 | Time-of-flight mass spectrometry method and apparatus |
JP2006228435A (en) * | 2005-02-15 | 2006-08-31 | Shimadzu Corp | Time of flight mass spectroscope |
JP4766549B2 (en) * | 2005-08-29 | 2011-09-07 | 株式会社島津製作所 | Laser irradiation mass spectrometer |
JP4645424B2 (en) * | 2005-11-24 | 2011-03-09 | 株式会社島津製作所 | Time-of-flight mass spectrometer |
US7385185B2 (en) * | 2005-12-20 | 2008-06-10 | Agilent Technologies, Inc. | Molecular activation for tandem mass spectroscopy |
JP2007280655A (en) * | 2006-04-04 | 2007-10-25 | Shimadzu Corp | Mass spectrometer |
GB0607542D0 (en) | 2006-04-13 | 2006-05-24 | Thermo Finnigan Llc | Mass spectrometer |
GB0622780D0 (en) * | 2006-11-15 | 2006-12-27 | Micromass Ltd | Mass spectrometer |
JP4743125B2 (en) * | 2007-01-22 | 2011-08-10 | 株式会社島津製作所 | Mass spectrometer |
-
2008
- 2008-01-11 US US12/013,352 patent/US7932487B2/en not_active Expired - Fee Related
- 2008-12-05 EP EP08870861A patent/EP2242560A2/en not_active Withdrawn
- 2008-12-05 CA CA2711534A patent/CA2711534A1/en not_active Abandoned
- 2008-12-05 WO PCT/US2008/085734 patent/WO2009091456A2/en active Application Filing
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2007066114A2 (en) * | 2005-12-07 | 2007-06-14 | Micromass Uk Limited | Mass spectrometer |
WO2007104992A2 (en) * | 2006-03-14 | 2007-09-20 | Micromass Uk Limited | Mass spectrometer |
Also Published As
Publication number | Publication date |
---|---|
EP2242560A2 (en) | 2010-10-27 |
WO2009091456A2 (en) | 2009-07-23 |
US7932487B2 (en) | 2011-04-26 |
US20090179150A1 (en) | 2009-07-16 |
CA2711534A1 (en) | 2009-07-23 |
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