WO2009128903A3 - Method to detect transmissible spongiform encephalopathies via electroretinogram - Google Patents

Method to detect transmissible spongiform encephalopathies via electroretinogram Download PDF

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Publication number
WO2009128903A3
WO2009128903A3 PCT/US2009/002325 US2009002325W WO2009128903A3 WO 2009128903 A3 WO2009128903 A3 WO 2009128903A3 US 2009002325 W US2009002325 W US 2009002325W WO 2009128903 A3 WO2009128903 A3 WO 2009128903A3
Authority
WO
WIPO (PCT)
Prior art keywords
wave
electroretinogram
transmissible spongiform
livestock
waveform
Prior art date
Application number
PCT/US2009/002325
Other languages
French (fr)
Other versions
WO2009128903A2 (en
Inventor
Justin J. Greenlee
Mary Heather West Greenlee
Original Assignee
The United States Of America, As Represented By The Secretary Of Agriculture
Iowa State University Research Foundation Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The United States Of America, As Represented By The Secretary Of Agriculture, Iowa State University Research Foundation Inc. filed Critical The United States Of America, As Represented By The Secretary Of Agriculture
Publication of WO2009128903A2 publication Critical patent/WO2009128903A2/en
Publication of WO2009128903A3 publication Critical patent/WO2009128903A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316—Modalities, i.e. specific diagnostic methods
    • A61B5/398—Electrooculography [EOG], e.g. detecting nystagmus; Electroretinography [ERG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/40—Detecting, measuring or recording for evaluating the nervous system
    • A61B5/4076—Diagnosing or monitoring particular conditions of the nervous system
    • A61B5/4088—Diagnosing of monitoring cognitive diseases, e.g. Alzheimer, prion diseases or dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2503/00—Evaluating a particular growth phase or type of persons or animals
    • A61B2503/40—Animals

Abstract

Disclosed is a method for identifying transmissible spongiform encephalopathy in livestock via an electroretinogram, the method comprises producing a biphasic electroretinogram waveform having an a-wave and b-wave from livestock retina in response to photic stimulus, measuring the amplitude of the b-wave, wherein the amplitude is measured from the trough of the a-wave to the peak of the b-wave, measuring the implicit time of the b-wave, wherein the implicit time is measured from onset of photic stimulus to b-wave peak; and comparing said produced waveform to a comparative waveform of livestock known not to have transmissible spongiform encephalopathy, wherein the produced waveform having a decrease b-wave amplitude and increased b-wave implicit time being indicative of livestock having transmissible spongiform encephalopathy.
PCT/US2009/002325 2008-04-15 2009-04-14 Method to detect transmissible spongiform encephalopathies via electroretinogram WO2009128903A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4500008P 2008-04-15 2008-04-15
US61/045,000 2008-04-15

Publications (2)

Publication Number Publication Date
WO2009128903A2 WO2009128903A2 (en) 2009-10-22
WO2009128903A3 true WO2009128903A3 (en) 2010-02-18

Family

ID=41163713

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2009/002325 WO2009128903A2 (en) 2008-04-15 2009-04-14 Method to detect transmissible spongiform encephalopathies via electroretinogram

Country Status (2)

Country Link
US (1) US8128227B2 (en)
WO (1) WO2009128903A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9071834B2 (en) * 2009-04-25 2015-06-30 James Yett Array of individually angled mirrors reflecting disparate color sources toward one or more viewing positions to construct images and visual effects
CA2905202C (en) 2013-03-14 2019-12-31 Universite Laval Use of electroretinography (erg) for the assessment of psychiatric disorders
MX2022012017A (en) * 2020-03-26 2022-12-15 Diamentis Inc Systems and methods for processing retinal signal data and identifying conditions.

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070059297A1 (en) * 2005-08-04 2007-03-15 Nestec, S.A. Methods and compositions for improving visual acuity
US20070224694A1 (en) * 2006-02-10 2007-09-27 Puchalski Daniel M Method and system for hyperspectral detection of animal diseases
US20080058655A1 (en) * 2006-08-19 2008-03-06 Severns Matthew L Device to monitor retinal ischemia

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH633952A5 (en) 1980-03-14 1983-01-14 Grounauer Pierre Alain DEVICE FOR MEASURING THE ELECTRIC POTENTIALS OF THE EYE.
JPH02167133A (en) 1987-03-28 1990-06-27 Toyo Medical Kk Method for measuring waveform of cornea potential chart
US4874237A (en) 1987-05-07 1989-10-17 Lions Eye Inst. Of Western Australia Electroretinogram apparatus
US6198532B1 (en) 1991-02-22 2001-03-06 Applied Spectral Imaging Ltd. Spectral bio-imaging of the eye
US5539482A (en) 1992-02-28 1996-07-23 The Australian National University Glaucoma testing using non-linear systems identification techniques
US5382987A (en) 1992-05-22 1995-01-17 Board Of Regents, The University Of Texas System Device for ERG spectral perimetry

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070059297A1 (en) * 2005-08-04 2007-03-15 Nestec, S.A. Methods and compositions for improving visual acuity
US20070224694A1 (en) * 2006-02-10 2007-09-27 Puchalski Daniel M Method and system for hyperspectral detection of animal diseases
US20080058655A1 (en) * 2006-08-19 2008-03-06 Severns Matthew L Device to monitor retinal ischemia

Also Published As

Publication number Publication date
WO2009128903A2 (en) 2009-10-22
US20090257023A1 (en) 2009-10-15
US8128227B2 (en) 2012-03-06

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