WO2009134719A3 - Apparatus and method for cross axis parallel spectroscopy - Google Patents

Apparatus and method for cross axis parallel spectroscopy Download PDF

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Publication number
WO2009134719A3
WO2009134719A3 PCT/US2009/041827 US2009041827W WO2009134719A3 WO 2009134719 A3 WO2009134719 A3 WO 2009134719A3 US 2009041827 W US2009041827 W US 2009041827W WO 2009134719 A3 WO2009134719 A3 WO 2009134719A3
Authority
WO
WIPO (PCT)
Prior art keywords
electro
dispersive
magnetic radiation
spectrum
radiation
Prior art date
Application number
PCT/US2009/041827
Other languages
French (fr)
Other versions
WO2009134719A2 (en
Inventor
Seok-Hyun Yun
Giuliano Scarcelli
Original Assignee
The General Hospital Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The General Hospital Corporation filed Critical The General Hospital Corporation
Publication of WO2009134719A2 publication Critical patent/WO2009134719A2/en
Publication of WO2009134719A3 publication Critical patent/WO2009134719A3/en

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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01JMEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/12Generating the spectrum; Monochromators
    • G01J3/26Generating the spectrum; Monochromators using multiple reflection, e.g. Fabry-Perot interferometer, variable interference filters
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01JMEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/02Details
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01JMEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/02Details
    • G01J3/0205Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows
    • G01J3/0208Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows using focussing or collimating elements, e.g. lenses or mirrors; performing aberration correction
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01JMEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/02Details
    • G01J3/0205Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows
    • G01J3/0229Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows using masks, aperture plates, spatial light modulators or spatial filters, e.g. reflective filters
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01JMEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/12Generating the spectrum; Monochromators
    • G01J3/14Generating the spectrum; Monochromators using refracting elements, e.g. prisms
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01JMEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/12Generating the spectrum; Monochromators
    • G01J3/18Generating the spectrum; Monochromators using diffraction elements, e.g. grating

Abstract

An exemplary embodiment of apparatus and method to measure and filter the spectrum of electro-magnetic radiation using multiple dispersive elements, such as diffraction gratings or VIPA etalons, concatenated in a cross-axis orthogonal arrangement can be provided. For example, it is possible to receive at least one first electro-magnetic radiation and generate at least one second electro-magnetic radiation using at least one first spectral separating arrangement. A first spectrum of the second electro-magnetic radiation can be dispersed along at least one first dispersive axis with respect to a propagation direction of the second electro-magnetic radiation. In addition, it is possible to, using at least one second arrangement, receive the second electro-magnetic radiation and produce at least one third electromagnetic radiation having a second spectrum dispersed along at least one second dispersive axis with respect to a propagation direction of the third electromagnetic radiation. The orientations of the respective first and second dispersive axes can be different from one another. The first and/or second dispersive arrangements can be VIPA etalon arrangements
PCT/US2009/041827 2008-04-30 2009-04-27 Apparatus and method for cross axis parallel spectroscopy WO2009134719A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12/112,205 2008-04-30
US12/112,205 US7898656B2 (en) 2008-04-30 2008-04-30 Apparatus and method for cross axis parallel spectroscopy

Publications (2)

Publication Number Publication Date
WO2009134719A2 WO2009134719A2 (en) 2009-11-05
WO2009134719A3 true WO2009134719A3 (en) 2010-02-18

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2009/041827 WO2009134719A2 (en) 2008-04-30 2009-04-27 Apparatus and method for cross axis parallel spectroscopy

Country Status (2)

Country Link
US (1) US7898656B2 (en)
WO (1) WO2009134719A2 (en)

Families Citing this family (103)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1434522B1 (en) 2000-10-30 2010-01-13 The General Hospital Corporation Optical systems for tissue analysis
US9295391B1 (en) 2000-11-10 2016-03-29 The General Hospital Corporation Spectrally encoded miniature endoscopic imaging probe
AT503309B1 (en) 2001-05-01 2011-08-15 Gen Hospital Corp DEVICE FOR DETERMINING ATHEROSCLEROTIC BEARING BY MEASURING OPTICAL TISSUE PROPERTIES
US7355716B2 (en) 2002-01-24 2008-04-08 The General Hospital Corporation Apparatus and method for ranging and noise reduction of low coherence interferometry LCI and optical coherence tomography OCT signals by parallel detection of spectral bands
CA2514189A1 (en) 2003-01-24 2004-08-12 The General Hospital Corporation System and method for identifying tissue using low-coherence interferometry
US7567349B2 (en) 2003-03-31 2009-07-28 The General Hospital Corporation Speckle reduction in optical coherence tomography by path length encoded angular compounding
US7643153B2 (en) 2003-01-24 2010-01-05 The General Hospital Corporation Apparatus and method for ranging and noise reduction of low coherence interferometry LCI and optical coherence tomography OCT signals by parallel detection of spectral bands
KR20130138867A (en) 2003-06-06 2013-12-19 더 제너럴 하스피탈 코포레이션 Process and apparatus for a wavelength tunning source
CN103181754A (en) 2003-10-27 2013-07-03 通用医疗公司 Method and apparatus for performing optical imaging using frequency-domain interferometry
WO2005117534A2 (en) 2004-05-29 2005-12-15 The General Hospital Corporation Process, system and software arrangement for a chromatic dispersion compensation using reflective layers in optical coherence tomography (oct) imaging
US7447408B2 (en) * 2004-07-02 2008-11-04 The General Hospital Corproation Imaging system and related techniques
US8081316B2 (en) 2004-08-06 2011-12-20 The General Hospital Corporation Process, system and software arrangement for determining at least one location in a sample using an optical coherence tomography
EP1793730B1 (en) 2004-08-24 2011-12-28 The General Hospital Corporation Process, system and software arrangement for determining elastic modulus
KR20120062944A (en) 2004-08-24 2012-06-14 더 제너럴 하스피탈 코포레이션 Method and apparatus for imaging of vessel segments
KR101269455B1 (en) 2004-09-10 2013-05-30 더 제너럴 하스피탈 코포레이션 System and method for optical coherence imaging
JP4997112B2 (en) 2004-09-29 2012-08-08 ザ ジェネラル ホスピタル コーポレイション Apparatus for transmitting at least one electromagnetic radiation and method of manufacturing the same
US7995210B2 (en) 2004-11-24 2011-08-09 The General Hospital Corporation Devices and arrangements for performing coherence range imaging using a common path interferometer
EP1816949A1 (en) 2004-11-29 2007-08-15 The General Hospital Corporation Arrangements, devices, endoscopes, catheters and methods for performing optical imaging by simultaneously illuminating and detecting multiple points on a sample
EP1875436B1 (en) 2005-04-28 2009-12-09 The General Hospital Corporation Evaluation of image features of an anatomical structure in optical coherence tomography images
JP5702049B2 (en) 2005-06-01 2015-04-15 ザ ジェネラル ホスピタル コーポレイション Apparatus, method and system for performing phase resolved optical frequency domain imaging
ES2354287T3 (en) 2005-08-09 2011-03-11 The General Hospital Corporation APPARATUS AND METHOD FOR PERFORMING A DEMODULATION IN QUADRATURE BY POLARIZATION IN OPTICAL COHERENCE TOMOGRAPHY.
JP6046325B2 (en) 2005-09-29 2016-12-14 ザ ジェネラル ホスピタル コーポレイション Method and apparatus for the observation and analysis of one or more biological samples with progressively increased resolution
US7889348B2 (en) 2005-10-14 2011-02-15 The General Hospital Corporation Arrangements and methods for facilitating photoluminescence imaging
WO2007082228A1 (en) 2006-01-10 2007-07-19 The General Hospital Corporation Systems and methods for generating data based on one or more spectrally-encoded endoscopy techniques
WO2007084903A2 (en) 2006-01-19 2007-07-26 The General Hospital Corporation Apparatus for obtaining information for a structure using spectrally-encoded endoscopy techniques and method for producing one or more optical arrangements
CN104257348A (en) 2006-01-19 2015-01-07 通用医疗公司 Methods And Systems For Optical Imaging Of Epithelial Luminal Organs By Beam Scanning Thereof
EP1986545A2 (en) 2006-02-01 2008-11-05 The General Hospital Corporation Apparatus for applying a plurality of electro-magnetic radiations to a sample
JP5524487B2 (en) 2006-02-01 2014-06-18 ザ ジェネラル ホスピタル コーポレイション A method and system for emitting electromagnetic radiation to at least a portion of a sample using a conformal laser treatment procedure.
EP1988825B1 (en) 2006-02-08 2016-12-21 The General Hospital Corporation Arrangements and systems for obtaining information associated with an anatomical sample using optical microscopy
WO2007101026A2 (en) 2006-02-24 2007-09-07 The General Hospital Corporation Methods and systems for performing angle-resolved fourier-domain optical coherence tomography
EP3150110B1 (en) 2006-05-10 2020-09-02 The General Hospital Corporation Processes, arrangements and systems for providing frequency domain imaging of a sample
JP2010501877A (en) 2006-08-25 2010-01-21 ザ ジェネラル ホスピタル コーポレイション Apparatus and method for improving optical coherence tomography imaging capabilities using volumetric filtering techniques
WO2008049118A2 (en) 2006-10-19 2008-04-24 The General Hospital Corporation Apparatus and method for obtaining and providing imaging information associated with at least one portion of a sample and effecting such portion(s)
EP2104968A1 (en) 2007-01-19 2009-09-30 The General Hospital Corporation Rotating disk reflection for fast wavelength scanning of dispersed broadband light
WO2008118781A2 (en) 2007-03-23 2008-10-02 The General Hospital Corporation Methods, arrangements and apparatus for utilizing a wavelength-swept laser using angular scanning and dispersion procedures
US10534129B2 (en) 2007-03-30 2020-01-14 The General Hospital Corporation System and method providing intracoronary laser speckle imaging for the detection of vulnerable plaque
WO2008131082A1 (en) 2007-04-17 2008-10-30 The General Hospital Corporation Apparatus and methods for measuring vibrations using spectrally-encoded endoscopy techniques
WO2009018456A2 (en) 2007-07-31 2009-02-05 The General Hospital Corporation Systems and methods for providing beam scan patterns for high speed doppler optical frequency domain imaging
JP5536650B2 (en) * 2007-08-31 2014-07-02 ザ ジェネラル ホスピタル コーポレイション System and method for self-interfering fluorescence microscopy and associated computer-accessible media
US7933021B2 (en) 2007-10-30 2011-04-26 The General Hospital Corporation System and method for cladding mode detection
US7898656B2 (en) * 2008-04-30 2011-03-01 The General Hospital Corporation Apparatus and method for cross axis parallel spectroscopy
EP2274572A4 (en) 2008-05-07 2013-08-28 Gen Hospital Corp System, method and computer-accessible medium for tracking vessel motion during three-dimensional coronary artery microscopy
JP5795531B2 (en) 2008-06-20 2015-10-14 ザ ジェネラル ホスピタル コーポレイション Fused fiber optic coupler structure and method of using the same
JP5667051B2 (en) 2008-07-14 2015-02-12 ザ ジェネラル ホスピタル コーポレイション Equipment for color endoscopy
US8440952B2 (en) * 2008-11-18 2013-05-14 The Regents Of The University Of California Methods for optical amplified imaging using a two-dimensional spectral brush
EP3330696B1 (en) 2008-12-10 2023-07-12 The General Hospital Corporation Systems, apparatus and methods for extending imaging depth range of optical coherence tomography through optical sub-sampling
WO2010090837A2 (en) 2009-01-20 2010-08-12 The General Hospital Corporation Endoscopic biopsy apparatus, system and method
JP2012515930A (en) 2009-01-26 2012-07-12 ザ ジェネラル ホスピタル コーポレーション System, method and computer-accessible medium for providing a wide-field super-resolution microscope
WO2010091190A2 (en) 2009-02-04 2010-08-12 The General Hospital Corporation Apparatus and method for utilization of a high-speed optical wavelength tuning source
US11490826B2 (en) 2009-07-14 2022-11-08 The General Hospital Corporation Apparatus, systems and methods for measuring flow and pressure within a vessel
WO2011050164A1 (en) 2009-10-21 2011-04-28 Avedro, Inc. Eye therapy
US8804126B2 (en) 2010-03-05 2014-08-12 The General Hospital Corporation Systems, methods and computer-accessible medium which provide microscopic images of at least one anatomical structure at a particular resolution
EP2547298B1 (en) 2010-03-19 2019-05-08 Avedro, Inc. Systems for applying and monitoring eye therapy
US9069130B2 (en) 2010-05-03 2015-06-30 The General Hospital Corporation Apparatus, method and system for generating optical radiation from biological gain media
EP2575597B1 (en) 2010-05-25 2022-05-04 The General Hospital Corporation Apparatus for providing optical imaging of structures and compositions
EP2575598A2 (en) 2010-05-25 2013-04-10 The General Hospital Corporation Apparatus, systems, methods and computer-accessible medium for spectral analysis of optical coherence tomography images
US10285568B2 (en) 2010-06-03 2019-05-14 The General Hospital Corporation Apparatus and method for devices for imaging structures in or at one or more luminal organs
US9510758B2 (en) 2010-10-27 2016-12-06 The General Hospital Corporation Apparatus, systems and methods for measuring blood pressure within at least one vessel
WO2012162529A1 (en) 2011-05-24 2012-11-29 Avedro, Inc. Systems and methods for reshaping an eye feature
JP6122845B2 (en) 2011-06-02 2017-04-26 アヴェドロ・インコーポレーテッドAvedro,Inc. System and method for monitoring the delivery of time-based photoactive agents or the presence of photoactive markers
US9330092B2 (en) 2011-07-19 2016-05-03 The General Hospital Corporation Systems, methods, apparatus and computer-accessible-medium for providing polarization-mode dispersion compensation in optical coherence tomography
WO2013029047A1 (en) 2011-08-25 2013-02-28 The General Hospital Corporation Methods, systems, arrangements and computer-accessible medium for providing micro-optical coherence tomography procedures
EP2769491A4 (en) 2011-10-18 2015-07-22 Gen Hospital Corp Apparatus and methods for producing and/or providing recirculating optical delay(s)
US8873040B2 (en) * 2012-01-19 2014-10-28 Mustard Tree Instruments, Llc Raman apparatus and method for real time calibration thereof
US9629528B2 (en) 2012-03-30 2017-04-25 The General Hospital Corporation Imaging system, method and distal attachment for multidirectional field of view endoscopy
WO2013177154A1 (en) 2012-05-21 2013-11-28 The General Hospital Corporation Apparatus, device and method for capsule microscopy
EP2872081B1 (en) 2012-07-16 2022-06-08 Avedro, Inc. Systems for corneal cross-linking with pulsed light
JP6227652B2 (en) 2012-08-22 2017-11-08 ザ ジェネラル ホスピタル コーポレイション System, method, and computer-accessible medium for fabricating a miniature endoscope using soft lithography
US9968261B2 (en) 2013-01-28 2018-05-15 The General Hospital Corporation Apparatus and method for providing diffuse spectroscopy co-registered with optical frequency domain imaging
WO2014120791A1 (en) 2013-01-29 2014-08-07 The General Hospital Corporation Apparatus, systems and methods for providing information regarding the aortic valve
WO2014121082A1 (en) 2013-02-01 2014-08-07 The General Hospital Corporation Objective lens arrangement for confocal endomicroscopy
EP2967491B1 (en) 2013-03-15 2022-05-11 The General Hospital Corporation A transesophageal endoscopic system for determining a mixed venous oxygen saturation of a pulmonary artery
WO2014186353A1 (en) 2013-05-13 2014-11-20 The General Hospital Corporation Detecting self-interefering fluorescence phase and amplitude
US9498114B2 (en) 2013-06-18 2016-11-22 Avedro, Inc. Systems and methods for determining biomechanical properties of the eye for applying treatment
WO2014205145A1 (en) 2013-06-18 2014-12-24 Avedro, Inc. Systems and methods for determining biomechanical properties of the eye for applying treatment
WO2015009932A1 (en) 2013-07-19 2015-01-22 The General Hospital Corporation Imaging apparatus and method which utilizes multidirectional field of view endoscopy
EP3021735A4 (en) 2013-07-19 2017-04-19 The General Hospital Corporation Determining eye motion by imaging retina. with feedback
ES2893237T3 (en) 2013-07-26 2022-02-08 Massachusetts Gen Hospital Apparatus with a laser arrangement using optical scattering for applications in optical coherence tomography in the Fourier domain
US9733460B2 (en) 2014-01-08 2017-08-15 The General Hospital Corporation Method and apparatus for microscopic imaging
WO2015116986A2 (en) 2014-01-31 2015-08-06 The General Hospital Corporation System and method for facilitating manual and/or automatic volumetric imaging with real-time tension or force feedback using a tethered imaging device
WO2015153982A1 (en) 2014-04-04 2015-10-08 The General Hospital Corporation Apparatus and method for controlling propagation and/or transmission of electromagnetic radiation in flexible waveguide(s)
EP3171766B1 (en) 2014-07-25 2021-12-29 The General Hospital Corporation Apparatus for in vivo imaging and diagnosis
CN107205845B (en) 2014-10-27 2020-03-31 艾维德洛公司 Systems and methods for cross-linking treatment of the eye
WO2016077747A1 (en) 2014-11-13 2016-05-19 Avedro, Inc. Multipass virtually imaged phased array etalon
EP3827792A1 (en) 2015-04-24 2021-06-02 Avedro, Inc. Systems and methods for photoactivating a photosensitizer applied to an eye
EP3297589A4 (en) 2015-05-22 2019-03-06 Avedro Inc. Systems and methods for monitoring cross-linking activity for corneal treatments
EP3324973B1 (en) 2015-07-21 2020-06-03 Avedro, Inc. Treament of an eye with a photosensitizer
EP3414535A4 (en) * 2016-02-12 2019-10-23 The General Hospital Corporation A system for performing spectroscopy
DE102016120308A1 (en) * 2016-10-25 2018-04-26 Carl Zeiss Microscopy Gmbh Optical arrangement, multi-spot scanning microscope and method for operating a microscope
US10495513B2 (en) * 2017-01-17 2019-12-03 Lightmachinery Inc. Multi-resolution optical spectrometer
US11143555B2 (en) 2017-01-27 2021-10-12 University Of Maryland, College Park Methods and devices for reducing spectral noise and spectrometry systems employing such devices
US10337987B2 (en) 2017-06-16 2019-07-02 Canon U.S.A. , Inc. Radial-line scanning spectrometer with two-dimensional sensor
EP3668368A4 (en) 2017-08-18 2021-08-18 The General Hospital Corporation Systems and methods for brillouin spectroscopy and imaging of tissues
US10837902B2 (en) * 2017-08-21 2020-11-17 Tokyo Electron Limited Optical sensor for phase determination
IT201700109143A1 (en) * 2017-09-29 2019-03-29 Fondazione St Italiano Tecnologia Arrangement to increase the spectral contrast of a VIPA spectrometer.
EP3761928A1 (en) 2018-03-08 2021-01-13 Avedro, Inc. Micro-devices for treatment of an eye
JP2019174151A (en) * 2018-03-27 2019-10-10 株式会社島津製作所 Spectrometer
US11060912B2 (en) 2018-12-06 2021-07-13 University Of Maryland, College Park Multi-stage parallel spectroscopy systems and methods
US11698303B2 (en) * 2018-12-28 2023-07-11 Spectral Engines Oy Method and system for analysing a chemical composition of a target using a Fabry-Perot interferometer
EP3748317A1 (en) * 2019-06-05 2020-12-09 Karlsruher Institut für Technologie A method and a device for acquiring spatially-resolved spectral information
EP4009928A4 (en) 2019-08-06 2023-08-02 Avedro, Inc. Photoactivation systems and methods for corneal cross-linking treatments
US10996109B1 (en) 2019-10-17 2021-05-04 Lightmachinery Inc. Etalon based optical spectrometer
US11422029B1 (en) 2019-11-22 2022-08-23 Intelon Optics, Inc. Managing stability in spectroscopy measurement systems

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003046495A1 (en) * 2001-11-21 2003-06-05 Delta E Refractive-diffractive spectrometer
JP2007271761A (en) * 2006-03-30 2007-10-18 Fujitsu Ltd Spectrometer and wavelength dispersion controller
US7304798B2 (en) * 2003-09-03 2007-12-04 Fujitsu Limited Spectroscopic apparatus
US20080002197A1 (en) * 2006-06-19 2008-01-03 Ke-Xun Sun Grating angle magnification enhanced angular sensor and scanner
US20080049220A1 (en) * 2006-08-28 2008-02-28 Federico Izzia Spectroscopic microscopy with image-driven analysis

Family Cites Families (246)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3090753A (en) * 1960-08-02 1963-05-21 Exxon Research Engineering Co Ester oil compositions containing acid anhydride
US3872407A (en) * 1972-09-01 1975-03-18 Us Navy Rapidly tunable laser
JPS584481Y2 (en) * 1973-06-23 1983-01-26 オリンパス光学工業株式会社 Naishikiyoushiyahenkankogakkei
US4030831A (en) * 1976-03-22 1977-06-21 The United States Of America As Represented By The Secretary Of The Navy Phase detector for optical figure sensing
US4224929A (en) * 1977-11-08 1980-09-30 Olympus Optical Co., Ltd. Endoscope with expansible cuff member and operation section
US5302025A (en) 1982-08-06 1994-04-12 Kleinerman Marcos Y Optical systems for sensing temperature and other physical parameters
CH663466A5 (en) * 1983-09-12 1987-12-15 Battelle Memorial Institute METHOD AND DEVICE FOR DETERMINING THE POSITION OF AN OBJECT IN RELATION TO A REFERENCE.
US4639999A (en) 1984-11-02 1987-02-03 Xerox Corporation High resolution, high efficiency I.R. LED printing array fabrication method
US4763977A (en) 1985-01-09 1988-08-16 Canadian Patents And Development Limited-Societe Optical fiber coupler with tunable coupling ratio and method of making
US5318024A (en) * 1985-03-22 1994-06-07 Massachusetts Institute Of Technology Laser endoscope for spectroscopic imaging
US4734578A (en) 1985-03-27 1988-03-29 Olympus Optical Co., Ltd. Two-dimensional scanning photo-electric microscope
US4650327A (en) * 1985-10-28 1987-03-17 Oximetrix, Inc. Optical catheter calibrating assembly
JPH0824665B2 (en) * 1986-11-28 1996-03-13 オリンパス光学工業株式会社 Endoscope device
US4744656A (en) * 1986-12-08 1988-05-17 Spectramed, Inc. Disposable calibration boot for optical-type cardiovascular catheter
US4751706A (en) * 1986-12-31 1988-06-14 The United States Of America As Represented By The Secretary Of The Army Laser for providing rapid sequence of different wavelengths
US4834111A (en) * 1987-01-12 1989-05-30 The Trustees Of Columbia University In The City Of New York Heterodyne interferometer
US5202931A (en) 1987-10-06 1993-04-13 Cell Analysis Systems, Inc. Methods and apparatus for the quantitation of nuclear protein
US4909631A (en) * 1987-12-18 1990-03-20 Tan Raul Y Method for film thickness and refractive index determination
US4890901A (en) * 1987-12-22 1990-01-02 Hughes Aircraft Company Color corrector for embedded prisms
US5730731A (en) * 1988-04-28 1998-03-24 Thomas J. Fogarty Pressure-based irrigation accumulator
US4998972A (en) * 1988-04-28 1991-03-12 Thomas J. Fogarty Real time angioscopy imaging system
US4905169A (en) * 1988-06-02 1990-02-27 The United States Of America As Represented By The United States Department Of Energy Method and apparatus for simultaneously measuring a plurality of spectral wavelengths present in electromagnetic radiation
US5242437A (en) * 1988-06-10 1993-09-07 Trimedyne Laser Systems, Inc. Medical device applying localized high intensity light and heat, particularly for destruction of the endometrium
US5214538A (en) * 1988-07-25 1993-05-25 Keymed (Medical And Industrial Equipment) Limited Optical apparatus
US4940328A (en) 1988-11-04 1990-07-10 Georgia Tech Research Corporation Optical sensing apparatus and method
US4966589A (en) 1988-11-14 1990-10-30 Hemedix International, Inc. Intravenous catheter placement device
US5085496A (en) * 1989-03-31 1992-02-04 Sharp Kabushiki Kaisha Optical element and optical pickup device comprising it
US5317389A (en) * 1989-06-12 1994-05-31 California Institute Of Technology Method and apparatus for white-light dispersed-fringe interferometric measurement of corneal topography
US4984888A (en) * 1989-12-13 1991-01-15 Imo Industries, Inc. Two-dimensional spectrometer
KR930003307B1 (en) * 1989-12-14 1993-04-24 주식회사 금성사 Three dimensional projector
US5251009A (en) 1990-01-22 1993-10-05 Ciba-Geigy Corporation Interferometric measuring arrangement for refractive index measurements in capillary tubes
US5241364A (en) * 1990-10-19 1993-08-31 Fuji Photo Film Co., Ltd. Confocal scanning type of phase contrast microscope and scanning microscope
US5250186A (en) 1990-10-23 1993-10-05 Cetus Corporation HPLC light scattering detector for biopolymers
US5275594A (en) * 1990-11-09 1994-01-04 C. R. Bard, Inc. Angioplasty system having means for identification of atherosclerotic plaque
US5784162A (en) 1993-08-18 1998-07-21 Applied Spectral Imaging Ltd. Spectral bio-imaging methods for biological research, medical diagnostics and therapy
US6111645A (en) 1991-04-29 2000-08-29 Massachusetts Institute Of Technology Grating based phase control optical delay line
US6134003A (en) 1991-04-29 2000-10-17 Massachusetts Institute Of Technology Method and apparatus for performing optical measurements using a fiber optic imaging guidewire, catheter or endoscope
US6501551B1 (en) 1991-04-29 2002-12-31 Massachusetts Institute Of Technology Fiber optic imaging endoscope interferometer with at least one faraday rotator
US6485413B1 (en) 1991-04-29 2002-11-26 The General Hospital Corporation Methods and apparatus for forward-directed optical scanning instruments
US5281811A (en) 1991-06-17 1994-01-25 Litton Systems, Inc. Digital wavelength division multiplex optical transducer having an improved decoder
US5208651A (en) * 1991-07-16 1993-05-04 The Regents Of The University Of California Apparatus and method for measuring fluorescence intensities at a plurality of wavelengths and lifetimes
US5212667A (en) * 1992-02-03 1993-05-18 General Electric Company Light imaging in a scattering medium, using ultrasonic probing and speckle image differencing
US5217456A (en) 1992-02-24 1993-06-08 Pdt Cardiovascular, Inc. Device and method for intra-vascular optical radial imaging
US5283795A (en) 1992-04-21 1994-02-01 Hughes Aircraft Company Diffraction grating driven linear frequency chirped laser
US5716324A (en) * 1992-08-25 1998-02-10 Fuji Photo Film Co., Ltd. Endoscope with surface and deep portion imaging systems
US5348003A (en) * 1992-09-03 1994-09-20 Sirraya, Inc. Method and apparatus for chemical analysis
JPH06222242A (en) 1993-01-27 1994-08-12 Shin Etsu Chem Co Ltd Optical fiber coupler and its manufacture
JP3112595B2 (en) * 1993-03-17 2000-11-27 安藤電気株式会社 Optical fiber strain position measuring device using optical frequency shifter
FI93781C (en) 1993-03-18 1995-05-26 Wallac Oy Biospecific multiparametric assay method
US5485079A (en) * 1993-03-29 1996-01-16 Matsushita Electric Industrial Co., Ltd. Magneto-optical element and optical magnetic field sensor
US5424827A (en) * 1993-04-30 1995-06-13 Litton Systems, Inc. Optical system and method for eliminating overlap of diffraction spectra
SE501932C2 (en) 1993-04-30 1995-06-26 Ericsson Telefon Ab L M Apparatus and method for dispersion compensation in a fiber optic transmission system
JP3234353B2 (en) * 1993-06-15 2001-12-04 富士写真フイルム株式会社 Tomographic information reader
DE4411017C2 (en) 1994-03-30 1995-06-08 Alexander Dr Knuettel Optical stationary spectroscopic imaging in strongly scattering objects through special light focusing and signal detection of light of different wavelengths
US5817144A (en) 1994-10-25 1998-10-06 Latis, Inc. Method for contemporaneous application OF laser energy and localized pharmacologic therapy
US5566267A (en) 1994-12-15 1996-10-15 Ceram Optec Industries Inc. Flat surfaced optical fibers and diode laser medical delivery devices
US5648848A (en) 1995-02-01 1997-07-15 Nikon Precision, Inc. Beam delivery apparatus and method for interferometry using rotatable polarization chucks
DE19506484C2 (en) 1995-02-24 1999-09-16 Stiftung Fuer Lasertechnologie Method and device for selective non-invasive laser myography (LMG)
JP3945820B2 (en) * 1995-03-24 2007-07-18 オプティスキャン ピーティーワイ リミテッド Optical fiber confocal image forming apparatus with variable near-confocal control means
US5565983A (en) * 1995-05-26 1996-10-15 The Perkin-Elmer Corporation Optical spectrometer for detecting spectra in separate ranges
US5785651A (en) * 1995-06-07 1998-07-28 Keravision, Inc. Distance measuring confocal microscope
US6016197A (en) * 1995-08-25 2000-01-18 Ceramoptec Industries Inc. Compact, all-optical spectrum analyzer for chemical and biological fiber optic sensors
FR2738343B1 (en) 1995-08-30 1997-10-24 Cohen Sabban Joseph OPTICAL MICROSTRATIGRAPHY DEVICE
US6763261B2 (en) 1995-09-20 2004-07-13 Board Of Regents, The University Of Texas System Method and apparatus for detecting vulnerable atherosclerotic plaque
ATE221338T1 (en) 1995-09-20 2002-08-15 Texas Heart Inst YINDICATION OF THERMAL DISCONTINUITY ON VESSEL WALLS
JP3699761B2 (en) 1995-12-26 2005-09-28 オリンパス株式会社 Epifluorescence microscope
US5748318A (en) * 1996-01-23 1998-05-05 Brown University Research Foundation Optical stress generator and detector
US5642194A (en) * 1996-02-05 1997-06-24 The Regents Of The University Of California White light velocity interferometer
US6020963A (en) * 1996-06-04 2000-02-01 Northeastern University Optical quadrature Interferometer
US6245026B1 (en) * 1996-07-29 2001-06-12 Farallon Medsystems, Inc. Thermography catheter
US6396941B1 (en) * 1996-08-23 2002-05-28 Bacus Research Laboratories, Inc. Method and apparatus for internet, intranet, and local viewing of virtual microscope slides
US6544193B2 (en) 1996-09-04 2003-04-08 Marcio Marc Abreu Noninvasive measurement of chemical substances
JPH1090603A (en) * 1996-09-18 1998-04-10 Olympus Optical Co Ltd Endscopic optical system
US5801831A (en) * 1996-09-20 1998-09-01 Institute For Space And Terrestrial Science Fabry-Perot spectrometer for detecting a spatially varying spectral signature of an extended source
US5752518A (en) 1996-10-28 1998-05-19 Ep Technologies, Inc. Systems and methods for visualizing interior regions of the body
US6517532B1 (en) * 1997-05-15 2003-02-11 Palomar Medical Technologies, Inc. Light energy delivery head
US6437867B2 (en) 1996-12-04 2002-08-20 The Research Foundation Of The City University Of New York Performing selected optical measurements with optical coherence domain reflectometry
US6249630B1 (en) 1996-12-13 2001-06-19 Imra America, Inc. Apparatus and method for delivery of dispersion-compensated ultrashort optical pulses with high peak power
US5836877A (en) 1997-02-24 1998-11-17 Lucid Inc System for facilitating pathological examination of a lesion in tissue
US6010449A (en) 1997-02-28 2000-01-04 Lumend, Inc. Intravascular catheter system for treating a vascular occlusion
US6078047A (en) 1997-03-14 2000-06-20 Lucent Technologies Inc. Method and apparatus for terahertz tomographic imaging
US5994690A (en) 1997-03-17 1999-11-30 Kulkarni; Manish D. Image enhancement in optical coherence tomography using deconvolution
US6297018B1 (en) 1998-04-17 2001-10-02 Ljl Biosystems, Inc. Methods and apparatus for detecting nucleic acid polymorphisms
US5955737A (en) * 1997-10-27 1999-09-21 Systems & Processes Engineering Corporation Chemometric analysis for extraction of individual fluorescence spectrum and lifetimes from a target mixture
US6037579A (en) 1997-11-13 2000-03-14 Biophotonics Information Laboratories, Ltd. Optical interferometer employing multiple detectors to detect spatially distorted wavefront in imaging of scattering media
US6107048A (en) 1997-11-20 2000-08-22 Medical College Of Georgia Research Institute, Inc. Method of detecting and grading dysplasia in epithelial tissue
WO1999039317A1 (en) 1998-01-28 1999-08-05 Ht Medical Systems, Inc. Interface device and method for interfacing instruments to medical procedure simulation system
EP2267507A3 (en) * 1998-02-26 2011-08-17 The General Hospital Corporation Confocal microscopy with multi-spectral encoding
US6831781B2 (en) 1998-02-26 2004-12-14 The General Hospital Corporation Confocal microscopy with multi-spectral encoding and system and apparatus for spectroscopically encoded confocal microscopy
DE19814057B4 (en) * 1998-03-30 2009-01-02 Carl Zeiss Meditec Ag Arrangement for optical coherence tomography and coherence topography
US6996549B2 (en) 1998-05-01 2006-02-07 Health Discovery Corporation Computer-aided image analysis
JPH11326826A (en) * 1998-05-13 1999-11-26 Sony Corp Illuminating method and illuminator
US5995223A (en) 1998-06-01 1999-11-30 Power; Joan Fleurette Apparatus for rapid phase imaging interferometry and method therefor
JPH11352409A (en) 1998-06-05 1999-12-24 Olympus Optical Co Ltd Fluorescence detector
WO2000030225A1 (en) 1998-11-13 2000-05-25 Research And Development Institute, Inc. Programmable frequency reference for laser frequency stabilization, and arbitrary optical clock generator, using persistent spectral hole burning
EP1002497B1 (en) * 1998-11-20 2006-07-26 Fuji Photo Film Co., Ltd. Blood vessel imaging system
US5975697A (en) 1998-11-25 1999-11-02 Oti Ophthalmic Technologies, Inc. Optical mapping apparatus with adjustable depth resolution
US6352502B1 (en) 1998-12-03 2002-03-05 Lightouch Medical, Inc. Methods for obtaining enhanced spectroscopic information from living tissue, noninvasive assessment of skin condition and detection of skin abnormalities
DE19908883A1 (en) * 1999-03-02 2000-09-07 Rainer Heintzmann Process for increasing the resolution of optical imaging
US6859275B2 (en) 1999-04-09 2005-02-22 Plain Sight Systems, Inc. System and method for encoded spatio-spectral information processing
US6611833B1 (en) 1999-06-23 2003-08-26 Tissueinformatics, Inc. Methods for profiling and classifying tissue using a database that includes indices representative of a tissue population
US6993170B2 (en) 1999-06-23 2006-01-31 Icoria, Inc. Method for quantitative analysis of blood vessel structure
GB9915082D0 (en) * 1999-06-28 1999-08-25 Univ London Optical fibre probe
JP2001046321A (en) 1999-08-09 2001-02-20 Asahi Optical Co Ltd Endoscope device
US6445939B1 (en) 1999-08-09 2002-09-03 Lightlab Imaging, Llc Ultra-small optical probes, imaging optics, and methods for using same
JP3869589B2 (en) 1999-09-02 2007-01-17 ペンタックス株式会社 Fiber bundle and endoscope apparatus
US6538817B1 (en) * 1999-10-25 2003-03-25 Aculight Corporation Method and apparatus for optical coherence tomography with a multispectral laser source
JP2003515129A (en) * 1999-11-19 2003-04-22 ジョビン イヴォン、インコーポレーテッド Compact spectrofluorometer
US7236637B2 (en) * 1999-11-24 2007-06-26 Ge Medical Systems Information Technologies, Inc. Method and apparatus for transmission and display of a compressed digitized image
US6738144B1 (en) * 1999-12-17 2004-05-18 University Of Central Florida Non-invasive method and low-coherence apparatus system analysis and process control
US6445485B1 (en) * 2000-01-21 2002-09-03 At&T Corp. Micro-machine polarization-state controller
US6475210B1 (en) 2000-02-11 2002-11-05 Medventure Technology Corp Light treatment of vulnerable atherosclerosis plaque
US6751490B2 (en) 2000-03-01 2004-06-15 The Board Of Regents Of The University Of Texas System Continuous optoacoustic monitoring of hemoglobin concentration and hematocrit
AU2001251114A1 (en) 2000-03-28 2001-10-08 Board Of Regents, The University Of Texas System Enhancing contrast in biological imaging
US6687013B2 (en) * 2000-03-28 2004-02-03 Hitachi, Ltd. Laser interferometer displacement measuring system, exposure apparatus, and electron beam lithography apparatus
US6567585B2 (en) * 2000-04-04 2003-05-20 Optiscan Pty Ltd Z sharpening for fibre confocal microscopes
US6692430B2 (en) 2000-04-10 2004-02-17 C2Cure Inc. Intra vascular imaging apparatus
AU2001259188A1 (en) 2000-04-27 2001-11-07 Iridex Corporation Method and apparatus for real-time detection, control and recording of sub-clinical therapeutic laser lesions during ocular laser photocoagulation
US6441959B1 (en) * 2000-05-19 2002-08-27 Avanex Corporation Method and system for testing a tunable chromatic dispersion, dispersion slope, and polarization mode dispersion compensator utilizing a virtually imaged phased array
US6301048B1 (en) * 2000-05-19 2001-10-09 Avanex Corporation Tunable chromatic dispersion and dispersion slope compensator utilizing a virtually imaged phased array
US6757467B1 (en) * 2000-07-25 2004-06-29 Optical Air Data Systems, Lp Optical fiber system
US6441356B1 (en) 2000-07-28 2002-08-27 Optical Biopsy Technologies Fiber-coupled, high-speed, angled-dual-axis optical coherence scanning microscopes
US6882432B2 (en) * 2000-08-08 2005-04-19 Zygo Corporation Frequency transform phase shifting interferometry
DE10042840A1 (en) 2000-08-30 2002-03-14 Leica Microsystems Device and method for exciting fluorescence microscope markers in multiphoton scanning microscopy
JP3842101B2 (en) 2000-10-31 2006-11-08 富士写真フイルム株式会社 Endoscope device
EP1409721A2 (en) 2000-11-13 2004-04-21 Gnothis Holding SA Detection of nucleic acid polymorphisms
US7027633B2 (en) 2000-11-30 2006-04-11 Foran David J Collaborative diagnostic systems
JP4786027B2 (en) * 2000-12-08 2011-10-05 オリンパス株式会社 Optical system and optical apparatus
US7230708B2 (en) 2000-12-28 2007-06-12 Dmitri Olegovich Lapotko Method and device for photothermal examination of microinhomogeneities
EP1221581A1 (en) 2001-01-04 2002-07-10 Universität Stuttgart Interferometer
WO2002054948A1 (en) 2001-01-11 2002-07-18 The Johns Hopkins University Assessment of tooth structure using laser based ultrasonics
US7177491B2 (en) * 2001-01-12 2007-02-13 Board Of Regents The University Of Texas System Fiber-based optical low coherence tomography
US6697652B2 (en) 2001-01-19 2004-02-24 Massachusetts Institute Of Technology Fluorescence, reflectance and light scattering spectroscopy for measuring tissue
US20020140942A1 (en) 2001-02-17 2002-10-03 Fee Michale Sean Acousto-optic monitoring and imaging in a depth sensitive manner
US6654127B2 (en) 2001-03-01 2003-11-25 Carl Zeiss Ophthalmic Systems, Inc. Optical delay line
US6721094B1 (en) * 2001-03-05 2004-04-13 Sandia Corporation Long working distance interference microscope
IL142773A (en) 2001-03-08 2007-10-31 Xtellus Inc Fiber optical attenuator
US7139598B2 (en) 2002-04-04 2006-11-21 Veralight, Inc. Determination of a measure of a glycation end-product or disease state using tissue fluorescence
US20020158211A1 (en) 2001-04-16 2002-10-31 Dakota Technologies, Inc. Multi-dimensional fluorescence apparatus and method for rapid and highly sensitive quantitative analysis of mixtures
US7616986B2 (en) 2001-05-07 2009-11-10 University Of Washington Optical fiber scanner for performing multimodal optical imaging
US6701181B2 (en) * 2001-05-31 2004-03-02 Infraredx, Inc. Multi-path optical catheter
US6615062B2 (en) 2001-05-31 2003-09-02 Infraredx, Inc. Referencing optical catheters
DE60219627T2 (en) 2001-06-04 2008-02-07 The General Hospital Corp., Boston IDENTIFICATION AND THERAPY OF SENSITIVE PLAQUE WITH PHOTODYNAMIC COMPOUNDS
DE10129651B4 (en) 2001-06-15 2010-07-08 Carl Zeiss Jena Gmbh Method for compensation of the dispersion in signals of short-coherence and / or OCT interferometers
US6702744B2 (en) 2001-06-20 2004-03-09 Advanced Cardiovascular Systems, Inc. Agents that stimulate therapeutic angiogenesis and techniques and devices that enable their delivery
DE10137530A1 (en) * 2001-08-01 2003-02-13 Presens Prec Sensing Gmbh Arrangement and method for multiple fluorescence measurement
AU2002337666A1 (en) * 2001-08-03 2003-02-17 Joseph A. Izatt Aspects of basic oct engine technologies for high speed optical coherence tomography and light source and other improvements in oct
US20030030816A1 (en) 2001-08-11 2003-02-13 Eom Tae Bong Nonlinearity error correcting method and phase angle measuring method for displacement measurement in two-freqency laser interferometer and displacement measurement system using the same
US6900899B2 (en) 2001-08-20 2005-05-31 Agilent Technologies, Inc. Interferometers with coated polarizing beam splitters that are rotated to optimize extinction ratios
EP1293925A1 (en) 2001-09-18 2003-03-19 Agfa-Gevaert Radiographic scoring method
US6961123B1 (en) 2001-09-28 2005-11-01 The Texas A&M University System Method and apparatus for obtaining information from polarization-sensitive optical coherence tomography
DE10150934A1 (en) 2001-10-09 2003-04-10 Zeiss Carl Jena Gmbh Depth resolved measurement and imaging of biological samples using laser scanning microscopy, whereby heterodyne detection and optical modulation is used to allow imaging of deep sample regions
US6980299B1 (en) 2001-10-16 2005-12-27 General Hospital Corporation Systems and methods for imaging a sample
US6658278B2 (en) 2001-10-17 2003-12-02 Terumo Cardiovascular Systems Corporation Steerable infrared imaging catheter having steering fins
DE60220541T2 (en) 2001-12-14 2007-10-04 Agilent Technologies, Inc. (n.d.Ges.d. Staates Delaware), Santa Clara EXTERNAL RESONATOR WITH RETRO REFLECTING DEVICE, ESPECIALLY FOR TUNING LASERS
US7365858B2 (en) 2001-12-18 2008-04-29 Massachusetts Institute Of Technology Systems and methods for phase measurements
US6975891B2 (en) 2001-12-21 2005-12-13 Nir Diagnostics Inc. Raman spectroscopic system with integrating cavity
EP1324051A1 (en) 2001-12-26 2003-07-02 Kevin R. Forrester Motion measuring device
US20080154090A1 (en) 2005-01-04 2008-06-26 Dune Medical Devices Ltd. Endoscopic System for In-Vivo Procedures
US7355716B2 (en) * 2002-01-24 2008-04-08 The General Hospital Corporation Apparatus and method for ranging and noise reduction of low coherence interferometry LCI and optical coherence tomography OCT signals by parallel detection of spectral bands
WO2003069272A1 (en) * 2002-02-14 2003-08-21 Imalux Corporation Method for studying an object and an optical interferometer for carrying out said method
US20030165263A1 (en) 2002-02-19 2003-09-04 Hamer Michael J. Histological assessment
US7006232B2 (en) 2002-04-05 2006-02-28 Case Western Reserve University Phase-referenced doppler optical coherence tomography
US7016048B2 (en) 2002-04-09 2006-03-21 The Regents Of The University Of California Phase-resolved functional optical coherence tomography: simultaneous imaging of the stokes vectors, structure, blood flow velocity, standard deviation and birefringence in biological samples
JP3834789B2 (en) 2002-05-17 2006-10-18 独立行政法人科学技術振興機構 Autonomous ultra-short optical pulse compression, phase compensation, waveform shaping device
US7272252B2 (en) 2002-06-12 2007-09-18 Clarient, Inc. Automated system for combining bright field and fluorescent microscopy
AU2003261158A1 (en) 2002-07-12 2004-02-02 Joe Izatt Method and device for quantitative image correction for optical coherence tomography
WO2004029566A1 (en) 2002-09-26 2004-04-08 Bio Techplex Corporation Method and apparatus for screening using a waveform modulated led
US6842254B2 (en) * 2002-10-16 2005-01-11 Fiso Technologies Inc. System and method for measuring an optical path difference in a sensing interferometer
DE10260256B9 (en) 2002-12-20 2007-03-01 Carl Zeiss Interferometer system and measuring / machining tool
GB0229734D0 (en) 2002-12-23 2003-01-29 Qinetiq Ltd Grading oestrogen and progesterone receptors expression
US7123363B2 (en) * 2003-01-03 2006-10-17 Rose-Hulman Institute Of Technology Speckle pattern analysis method and system
US7075658B2 (en) 2003-01-24 2006-07-11 Duke University Method for optical coherence tomography imaging with molecular contrast
US7643153B2 (en) 2003-01-24 2010-01-05 The General Hospital Corporation Apparatus and method for ranging and noise reduction of low coherence interferometry LCI and optical coherence tomography OCT signals by parallel detection of spectral bands
US6943892B2 (en) * 2003-01-29 2005-09-13 Sarnoff Corporation Instrument having a multi-mode optical element and method
JP4338412B2 (en) * 2003-02-24 2009-10-07 Hoya株式会社 Confocal probe and confocal microscope
US7271918B2 (en) 2003-03-06 2007-09-18 Zygo Corporation Profiling complex surface structures using scanning interferometry
US7110109B2 (en) 2003-04-18 2006-09-19 Ahura Corporation Raman spectroscopy system and method and specimen holder therefor
WO2004098396A2 (en) * 2003-05-01 2004-11-18 The Cleveland Clinic Foundation Method and apparatus for measuring a retinal sublayer characteristic
US7355721B2 (en) * 2003-05-05 2008-04-08 D4D Technologies, Llc Optical coherence tomography imaging
CN100522043C (en) 2003-05-12 2009-08-05 富士能株式会社 Airbag type endoscope
WO2004111929A2 (en) 2003-05-28 2004-12-23 Duke University Improved system for fourier domain optical coherence tomography
EP1644697A4 (en) * 2003-05-30 2006-11-29 Univ Duke System and method for low coherence broadband quadrature interferometry
US6943881B2 (en) 2003-06-04 2005-09-13 Tomophase Corporation Measurements of optical inhomogeneity and other properties in substances using propagation modes of light
KR20130138867A (en) 2003-06-06 2013-12-19 더 제너럴 하스피탈 코포레이션 Process and apparatus for a wavelength tunning source
US7458683B2 (en) 2003-06-16 2008-12-02 Amo Manufacturing Usa, Llc Methods and devices for registering optical measurement datasets of an optical system
US7307734B2 (en) 2003-08-14 2007-12-11 University Of Central Florida Interferometric sensor for characterizing materials
US7539530B2 (en) 2003-08-22 2009-05-26 Infraredx, Inc. Method and system for spectral examination of vascular walls through blood during cardiac motion
US20050057680A1 (en) * 2003-09-16 2005-03-17 Agan Martin J. Method and apparatus for controlling integration time in imagers
US20050059894A1 (en) 2003-09-16 2005-03-17 Haishan Zeng Automated endoscopy device, diagnostic method, and uses
US7935055B2 (en) 2003-09-19 2011-05-03 Siemens Medical Solutions Usa, Inc. System and method of measuring disease severity of a patient before, during and after treatment
US6949072B2 (en) * 2003-09-22 2005-09-27 Infraredx, Inc. Devices for vulnerable plaque detection
US7142835B2 (en) 2003-09-29 2006-11-28 Silicon Laboratories, Inc. Apparatus and method for digital image correction in a receiver
CN103181754A (en) 2003-10-27 2013-07-03 通用医疗公司 Method and apparatus for performing optical imaging using frequency-domain interferometry
US7130320B2 (en) 2003-11-13 2006-10-31 Mitutoyo Corporation External cavity laser with rotary tuning element
WO2005054780A1 (en) 2003-11-28 2005-06-16 The General Hospital Corporation Method and apparatus for three-dimensional spectrally encoded imaging
US7359062B2 (en) * 2003-12-09 2008-04-15 The Regents Of The University Of California High speed spectral domain functional optical coherence tomography and optical doppler tomography for in vivo blood flow dynamics and tissue structure
DE10358735B4 (en) * 2003-12-15 2011-04-21 Siemens Ag Catheter device comprising a catheter, in particular an intravascular catheter
EP1722669A4 (en) 2004-02-27 2009-05-27 Optiscan Pty Ltd Optical element
US7190464B2 (en) * 2004-05-14 2007-03-13 Medeikon Corporation Low coherence interferometry for detecting and characterizing plaques
US7242480B2 (en) * 2004-05-14 2007-07-10 Medeikon Corporation Low coherence interferometry for detecting and characterizing plaques
WO2005117534A2 (en) 2004-05-29 2005-12-15 The General Hospital Corporation Process, system and software arrangement for a chromatic dispersion compensation using reflective layers in optical coherence tomography (oct) imaging
KR101269455B1 (en) 2004-09-10 2013-05-30 더 제너럴 하스피탈 코포레이션 System and method for optical coherence imaging
JP4997112B2 (en) * 2004-09-29 2012-08-08 ザ ジェネラル ホスピタル コーポレイション Apparatus for transmitting at least one electromagnetic radiation and method of manufacturing the same
US7113625B2 (en) 2004-10-01 2006-09-26 U.S. Pathology Labs, Inc. System and method for image analysis of slides
SE0402435L (en) 2004-10-08 2006-04-09 Trajan Badju Process and system for generating three-dimensional images
EP2272424A1 (en) 2004-10-29 2011-01-12 The General Hospital Corporation Polarisation-sensitive optical coherence tomography
JP5623692B2 (en) 2004-11-02 2014-11-12 ザ ジェネラル ホスピタル コーポレイション Optical fiber rotator, optical system and method for sample imaging
US7417740B2 (en) * 2004-11-12 2008-08-26 Medeikon Corporation Single trace multi-channel low coherence interferometric sensor
WO2006058187A2 (en) 2004-11-23 2006-06-01 Robert Eric Betzig Optical lattice microscopy
GB0426609D0 (en) 2004-12-03 2005-01-05 Ic Innovations Ltd Analysis
JP2006162366A (en) 2004-12-06 2006-06-22 Fujinon Corp Optical tomographic imaging system
US7450242B2 (en) * 2004-12-10 2008-11-11 Fujifilm Corporation Optical tomography apparatus
US7336366B2 (en) * 2005-01-20 2008-02-26 Duke University Methods and systems for reducing complex conjugate ambiguity in interferometric data
US7342659B2 (en) * 2005-01-21 2008-03-11 Carl Zeiss Meditec, Inc. Cross-dispersed spectrometer in a spectral domain optical coherence tomography system
US7330270B2 (en) 2005-01-21 2008-02-12 Carl Zeiss Meditec, Inc. Method to suppress artifacts in frequency-domain optical coherence tomography
HU227859B1 (en) 2005-01-27 2012-05-02 E Szilveszter Vizi Real-time 3d nonlinear microscope measuring system and its application
US7267494B2 (en) * 2005-02-01 2007-09-11 Finisar Corporation Fiber stub for cladding mode coupling reduction
US7664300B2 (en) 2005-02-03 2010-02-16 Sti Medical Systems, Llc Uterine cervical cancer computer-aided-diagnosis (CAD)
EP1910996A1 (en) 2005-02-23 2008-04-16 Lyncee Tec S.A. Wave front sensing method and apparatus
JP4628820B2 (en) 2005-02-25 2011-02-09 サンテック株式会社 Wavelength scanning fiber laser light source
US7530948B2 (en) 2005-02-28 2009-05-12 University Of Washington Tethered capsule endoscope for Barrett's Esophagus screening
JP2008538612A (en) 2005-04-22 2008-10-30 ザ ジェネラル ホスピタル コーポレイション Configuration, system, and method capable of providing spectral domain polarization sensitive optical coherence tomography
WO2006116362A2 (en) 2005-04-25 2006-11-02 The Trustees Of Boston University Structured substrates for optical surface profiling
WO2006124860A1 (en) 2005-05-13 2006-11-23 The General Hospital Corporation Arrangements, systems and methods capable of providing spectral-domain optical coherence reflectometry for a sensitive detection of chemical and biological sample
US7391520B2 (en) * 2005-07-01 2008-06-24 Carl Zeiss Meditec, Inc. Fourier domain optical coherence tomography employing a swept multi-wavelength laser and a multi-channel receiver
KR100743591B1 (en) 2005-09-23 2007-07-27 한국과학기술원 Confocal Self-Interference Microscopy Which Excluding Side Lobes
US7400410B2 (en) 2005-10-05 2008-07-15 Carl Zeiss Meditec, Inc. Optical coherence tomography for eye-length measurement
US7545504B2 (en) 2005-10-07 2009-06-09 Biotigen, Inc. Imaging systems using unpolarized light and related methods and controllers
WO2007044786A2 (en) * 2005-10-11 2007-04-19 Zygo Corporation Interferometry method and system including spectral decomposition
JP2009511909A (en) * 2005-10-11 2009-03-19 デユーク・ユニバーシテイ System and method for angle resolved low coherence interferometry with endoscope
US7408649B2 (en) 2005-10-26 2008-08-05 Kla-Tencor Technologies Corporation Method and apparatus for optically analyzing a surface
WO2007084945A1 (en) * 2006-01-19 2007-07-26 The General Hospital Corporation Systems and methods for performing rapid fluorescense lifetime, excitation and emission spectral measurements
WO2007084903A2 (en) 2006-01-19 2007-07-26 The General Hospital Corporation Apparatus for obtaining information for a structure using spectrally-encoded endoscopy techniques and method for producing one or more optical arrangements
GB0601183D0 (en) 2006-01-20 2006-03-01 Perkinelmer Ltd Improvements in and relating to imaging
CN101466298B (en) 2006-04-05 2011-08-31 通用医疗公司 Methods arrangements and systems for polarization-sensitive optical frequency domain imaging of a sample
WO2007127395A2 (en) 2006-04-28 2007-11-08 Bioptigen, Inc. Methods, systems and computer program products for optical coherence tomography (oct) using automatic dispersion compensation
WO2007133964A2 (en) 2006-05-12 2007-11-22 The General Hospital Corporation Processes, arrangements and systems for providing a fiber layer thickness map based on optical coherence tomography images
US20070291277A1 (en) 2006-06-20 2007-12-20 Everett Matthew J Spectral domain optical coherence tomography system
WO2008049118A2 (en) 2006-10-19 2008-04-24 The General Hospital Corporation Apparatus and method for obtaining and providing imaging information associated with at least one portion of a sample and effecting such portion(s)
EP2087400B1 (en) 2006-10-26 2019-10-16 Cornell Research Foundation, Inc. Production of optical pulses at a desired wavelength using soliton self-frequency shift in higher-order-mode fiber
US20080204762A1 (en) 2007-01-17 2008-08-28 Duke University Methods, systems, and computer program products for removing undesired artifacts in fourier domain optical coherence tomography (FDOCT) systems using integrating buckets
JP5192247B2 (en) 2008-01-29 2013-05-08 並木精密宝石株式会社 OCT probe
US7898656B2 (en) * 2008-04-30 2011-03-01 The General Hospital Corporation Apparatus and method for cross axis parallel spectroscopy
US8184298B2 (en) 2008-05-21 2012-05-22 The Board Of Trustees Of The University Of Illinois Spatial light interference microscopy and fourier transform light scattering for cell and tissue characterization
US8133127B1 (en) 2008-07-21 2012-03-13 Synder Terrance W Sports training device and methods of use

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003046495A1 (en) * 2001-11-21 2003-06-05 Delta E Refractive-diffractive spectrometer
US7304798B2 (en) * 2003-09-03 2007-12-04 Fujitsu Limited Spectroscopic apparatus
JP2007271761A (en) * 2006-03-30 2007-10-18 Fujitsu Ltd Spectrometer and wavelength dispersion controller
US20080002197A1 (en) * 2006-06-19 2008-01-03 Ke-Xun Sun Grating angle magnification enhanced angular sensor and scanner
US20080049220A1 (en) * 2006-08-28 2008-02-28 Federico Izzia Spectroscopic microscopy with image-driven analysis

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