WO2010061387A3 - Apparatus for transportation of oxygen to implanted cells - Google Patents

Apparatus for transportation of oxygen to implanted cells Download PDF

Info

Publication number
WO2010061387A3
WO2010061387A3 PCT/IL2009/001114 IL2009001114W WO2010061387A3 WO 2010061387 A3 WO2010061387 A3 WO 2010061387A3 IL 2009001114 W IL2009001114 W IL 2009001114W WO 2010061387 A3 WO2010061387 A3 WO 2010061387A3
Authority
WO
WIPO (PCT)
Prior art keywords
oxygen
transportation
housing
implanted cells
functional cells
Prior art date
Application number
PCT/IL2009/001114
Other languages
French (fr)
Other versions
WO2010061387A2 (en
Inventor
Yaki Stern
Uriel Barkai
Avi Rotem
Meir Reingewirtz
Yoram Rozy
Original Assignee
Beta O2 Technologies Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beta O2 Technologies Ltd. filed Critical Beta O2 Technologies Ltd.
Priority to CA2744643A priority Critical patent/CA2744643C/en
Priority to CN200980155498.6A priority patent/CN102292049B/en
Priority to EP09828728.7A priority patent/EP2370021B1/en
Priority to AU2009321193A priority patent/AU2009321193B2/en
Priority to ES09828728.7T priority patent/ES2650496T3/en
Priority to DK09828728.7T priority patent/DK2370021T3/en
Publication of WO2010061387A2 publication Critical patent/WO2010061387A2/en
Publication of WO2010061387A3 publication Critical patent/WO2010061387A3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M13/00Insufflators for therapeutic or disinfectant purposes, i.e. devices for blowing a gas, powder or vapour into the body
    • A61M13/003Blowing gases other than for carrying powders, e.g. for inflating, dilating or rinsing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/022Artificial gland structures using bioreactors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00Special media to be introduced, removed or treated
    • A61M2202/02Gases
    • A61M2202/0208Oxygen

Abstract

Apparatus is provided which includes a housing (24), configured for insertion into a body of a subject. The apparatus includes functional cells (32) coupled to the housing (24) and a source of oxygen configured to supply oxygen to the functional cells. The apparatus further includes an oxygen delivery interface (27) configured to receive oxygen from the source of oxygen, and to facilitate passage of the oxygen to the functional cells (32), while the housing (24) is disposed within the body of the subject. Other applications are also described.
PCT/IL2009/001114 2008-11-26 2009-11-25 Apparatus for transportation of oxygen to implanted cells WO2010061387A2 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
CA2744643A CA2744643C (en) 2008-11-26 2009-11-25 Apparatus for transportation of oxygen to implanted cells
CN200980155498.6A CN102292049B (en) 2008-11-26 2009-11-25 Apparatus for transportation of oxygen to implanted cells
EP09828728.7A EP2370021B1 (en) 2008-11-26 2009-11-25 Apparatus for transportation of oxygen to implanted cells
AU2009321193A AU2009321193B2 (en) 2008-11-26 2009-11-25 Apparatus for transportation of oxygen to implanted cells
ES09828728.7T ES2650496T3 (en) 2008-11-26 2009-11-25 Oxygen transport device to implanted cells
DK09828728.7T DK2370021T3 (en) 2008-11-26 2009-11-25 Device for transporting oxygen to implanted cells

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12/315,102 US8043271B2 (en) 2008-11-26 2008-11-26 Apparatus for transportation of oxygen to implanted cells
US12/315,102 2008-11-26

Publications (2)

Publication Number Publication Date
WO2010061387A2 WO2010061387A2 (en) 2010-06-03
WO2010061387A3 true WO2010061387A3 (en) 2010-08-12

Family

ID=42196972

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IL2009/001114 WO2010061387A2 (en) 2008-11-26 2009-11-25 Apparatus for transportation of oxygen to implanted cells

Country Status (8)

Country Link
US (1) US8043271B2 (en)
EP (1) EP2370021B1 (en)
CN (1) CN102292049B (en)
AU (1) AU2009321193B2 (en)
CA (1) CA2744643C (en)
DK (1) DK2370021T3 (en)
ES (1) ES2650496T3 (en)
WO (1) WO2010061387A2 (en)

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US9446168B2 (en) 2010-06-07 2016-09-20 Beta-O2 Technologies Ltd. Multiple-layer immune barrier for donor cells
US9540630B2 (en) * 2008-09-17 2017-01-10 Beta O2 Technologies Ltd. Optimization of alginate encapsulation of islets for transplantation
US10091985B2 (en) * 2009-06-18 2018-10-09 Giner, Inc. Perfusing an organ with an in situ generated gas
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US10231817B2 (en) 2013-09-24 2019-03-19 Giner Life Sciences, Inc. System for gas treatment of a cell implant
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US10871487B2 (en) 2016-04-20 2020-12-22 Glusense Ltd. FRET-based glucose-detection molecules
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AU2017396754B2 (en) * 2016-11-03 2021-08-05 Arizona Board Of Regents On Behalf Of The University Of Arizona Methods and systems for real-time assessment of cells in encapsulation devices pre-and post-transplantation
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AU2017361260B2 (en) * 2016-11-15 2023-06-08 Giner, Inc. Percutaneous gas diffusion device suitable for use with a subcutaneous implant
EP3541450B1 (en) 2016-11-15 2021-12-29 Giner Life Sciences, Inc. Self-regulating electrolytic gas generator and implant system comprising the same
US11642501B2 (en) 2017-05-04 2023-05-09 Giner, Inc. Robust, implantable gas delivery device and methods, systems and devices including same
WO2019222704A1 (en) * 2018-05-17 2019-11-21 Giner Life Sciences, Inc. Electrolytic gas generator with combined lead and gas port terminals
WO2020068852A1 (en) * 2018-09-24 2020-04-02 Procyon Technologies Llc Methods and systems for implantable medical devices and vascularization membranes
CN110548207B (en) * 2019-09-09 2021-04-09 吉林大学 Anesthetic direct injection device for painless childbirth
CA3196876A1 (en) * 2020-10-30 2022-05-05 Klearchos Papas Methods and systems for encapsulation devices for housing cells and agents
WO2022125795A1 (en) * 2020-12-09 2022-06-16 Cornell University Methods and devices for providing oxygen to encapsulated cells
EP4197491A1 (en) * 2021-12-20 2023-06-21 Technische Universität Dresden Modular implantable device for the macroencapsulation of cells

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Also Published As

Publication number Publication date
US8043271B2 (en) 2011-10-25
CA2744643A1 (en) 2010-06-03
DK2370021T3 (en) 2017-11-13
US20100130916A1 (en) 2010-05-27
AU2009321193A1 (en) 2011-07-21
CA2744643C (en) 2017-08-15
EP2370021B1 (en) 2017-09-06
CN102292049A (en) 2011-12-21
EP2370021A4 (en) 2014-05-21
CN102292049B (en) 2015-04-15
EP2370021A2 (en) 2011-10-05
ES2650496T3 (en) 2018-01-18
AU2009321193B2 (en) 2015-07-09
WO2010061387A2 (en) 2010-06-03

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