WO2010068295A3 - Three-dimensionally shaped interpenetrating network hydrogels - Google Patents

Three-dimensionally shaped interpenetrating network hydrogels Download PDF

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Publication number
WO2010068295A3
WO2010068295A3 PCT/US2009/006525 US2009006525W WO2010068295A3 WO 2010068295 A3 WO2010068295 A3 WO 2010068295A3 US 2009006525 W US2009006525 W US 2009006525W WO 2010068295 A3 WO2010068295 A3 WO 2010068295A3
Authority
WO
WIPO (PCT)
Prior art keywords
network
shape
ipn
interpenetrating network
dimensionally shaped
Prior art date
Application number
PCT/US2009/006525
Other languages
French (fr)
Other versions
WO2010068295A2 (en
Inventor
Philip Huie
Dale Jon Waters
Curtis W. Frank
Christopher N. Ta
Ariane C. Tom
Original Assignee
The Board Of Trustees Of The Leland Stanford Junior University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Board Of Trustees Of The Leland Stanford Junior University filed Critical The Board Of Trustees Of The Leland Stanford Junior University
Publication of WO2010068295A2 publication Critical patent/WO2010068295A2/en
Publication of WO2010068295A3 publication Critical patent/WO2010068295A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/52—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/26—Mixtures of macromolecular compounds
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B1/00—Optical elements characterised by the material of which they are made; Optical coatings for optical elements
    • G02B1/04—Optical elements characterised by the material of which they are made; Optical coatings for optical elements made of organic materials, e.g. plastics
    • G02B1/041—Lenses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/16—Materials or treatment for tissue regeneration for reconstruction of eye parts, e.g. intraocular lens, cornea

Abstract

Three-dimensionally (3-D) shaped interpenetrating double network (IPN) hydrogel based on a first network and a second network are provided. The 3- D shape is characterized by a non-uniform distribution of the second network (e.g. carboxylic acid groups) when in hydrated state. The 3-D shape can further be characterized by changes in the radius of curvature of the shape. The 3-D IPN hydrogel is created by applying a non-uniform illumination pattern to polymerize the second network of monomers within a layer of a first network. In hydrated state, the second network causes a swelling force that is resisted by the first network. The non-uniformal distribution of the second network with the first network is responsible for the 3-D of the resulting IPN. The invention can find use in ophthalmic applications as well as non- ophthalmic applications.
PCT/US2009/006525 2008-12-11 2009-12-11 Three-dimensionally shaped interpenetrating network hydrogels WO2010068295A2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US20171108P 2008-12-11 2008-12-11
US61/201,711 2008-12-11
US27054609P 2009-07-08 2009-07-08
US61/270,546 2009-07-08

Publications (2)

Publication Number Publication Date
WO2010068295A2 WO2010068295A2 (en) 2010-06-17
WO2010068295A3 true WO2010068295A3 (en) 2010-10-21

Family

ID=42243264

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2009/006525 WO2010068295A2 (en) 2008-12-11 2009-12-11 Three-dimensionally shaped interpenetrating network hydrogels

Country Status (1)

Country Link
WO (1) WO2010068295A2 (en)

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5522888A (en) * 1986-10-16 1996-06-04 Cbs Lens, A California General Partnership Collagen-hydrogel for promoting epithelial cell growth and regeneration of the stroma
US5567435A (en) * 1992-02-28 1996-10-22 Board Of Regents, The University Of Texas System Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers
US5661218A (en) * 1994-07-22 1997-08-26 Staar Surgical Company, Inc. Biocompatible optically transparent polymeric material based upon collagen and method of making
US20060074182A1 (en) * 2004-09-30 2006-04-06 Depuy Products, Inc. Hydrogel composition and methods for making the same
US7192693B2 (en) * 2004-02-24 2007-03-20 University Of Washington Methods for photopatterning hydrogels
US20070116765A1 (en) * 2003-12-09 2007-05-24 Zhibing Hu Aqueous dispersion of hydrogel nanoparticles with inverse thermoreversible gelation
US20080241214A1 (en) * 2007-02-06 2008-10-02 David Myung Hydrogel-metal assembly

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5522888A (en) * 1986-10-16 1996-06-04 Cbs Lens, A California General Partnership Collagen-hydrogel for promoting epithelial cell growth and regeneration of the stroma
US5567435A (en) * 1992-02-28 1996-10-22 Board Of Regents, The University Of Texas System Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers
US5661218A (en) * 1994-07-22 1997-08-26 Staar Surgical Company, Inc. Biocompatible optically transparent polymeric material based upon collagen and method of making
US20070116765A1 (en) * 2003-12-09 2007-05-24 Zhibing Hu Aqueous dispersion of hydrogel nanoparticles with inverse thermoreversible gelation
US7192693B2 (en) * 2004-02-24 2007-03-20 University Of Washington Methods for photopatterning hydrogels
US20060074182A1 (en) * 2004-09-30 2006-04-06 Depuy Products, Inc. Hydrogel composition and methods for making the same
US20080241214A1 (en) * 2007-02-06 2008-10-02 David Myung Hydrogel-metal assembly

Also Published As

Publication number Publication date
WO2010068295A2 (en) 2010-06-17

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